sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4de1 | 0J6 | Beta-lactamase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4de1 | 0J6 | Beta-lactamase | / | 1.000 | |
| 4de2 | DN3 | Beta-lactamase | / | 0.690 | |
| 3hlw | CE3 | Beta-lactamase | / | 0.682 | |
| 4de0 | 0JB | Beta-lactamase | / | 0.660 | |
| 4ddy | DN6 | Beta-lactamase | / | 0.625 | |
| 4de3 | DN8 | Beta-lactamase | / | 0.616 | |
| 3q1f | YPP | Beta-lactamase | / | 0.561 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.518 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.511 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.511 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.507 | |
| 4b1e | 6T6 | Beta-secretase 1 | 3.4.23.46 | 0.505 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.504 | |
| 3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.501 | |
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 0.498 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.496 | |
| 4m5p | FMN | NADPH dehydrogenase | / | 0.496 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.495 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.495 | |
| 4e2d | FMN | Dehydrogenase | / | 0.495 | |
| 1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.494 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.494 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.493 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.492 | |
| 2ilv | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.492 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.492 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.491 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.491 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.491 | |
| 4tta | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.491 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.490 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.490 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.490 | |
| 3wyc | NAP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.490 | |
| 3a3g | DLZ | Lumazine protein | / | 0.489 | |
| 4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.489 | |
| 4fsl | 0VB | Beta-secretase 1 | 3.4.23.46 | 0.489 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.488 | |
| 1x27 | ASP_TYR_VAL_HIS_PTR | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.488 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.488 | |
| 3dzi | RGT | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.488 | |
| 4k9h | 1QU | Beta-secretase 1 | 3.4.23.46 | 0.488 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.487 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.487 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.487 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.487 | |
| 2abj | PLP | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.486 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.486 | |
| 2p9c | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.486 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.486 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.486 | |
| 1szf | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.485 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.485 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.485 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.485 | |
| 1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.484 | |
| 4u0m | ATP | Cyclic GMP-AMP synthase | / | 0.484 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.483 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.483 | |
| 2bsx | NOS | Purine nucleoside phosphorylase | / | 0.483 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.483 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.483 | |
| 3opx | U5P | Suppressor of disruption of TFIIS | / | 0.483 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.483 | |
| 1c9k | 5GP | Bifunctional adenosylcobalamin biosynthesis protein CobU | / | 0.482 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.482 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.482 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.482 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.482 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.482 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.482 | |
| 3n19 | FNR | Xenobiotic reductase | / | 0.482 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.482 | |
| 4fuj | 1U9 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.482 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.482 | |
| 4x5i | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.482 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.481 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.481 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.481 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.481 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.480 | |
| 2yd0 | BES | Endoplasmic reticulum aminopeptidase 1 | 3.4.11 | 0.480 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.480 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.480 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.480 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.480 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.480 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.479 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.479 | |
| 3d3x | ARG_ILE_MET_GLU_NH2 | Type E botulinum toxin | / | 0.479 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.479 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.479 | |
| 3zkb | ANP | DNA gyrase subunit B | / | 0.479 | |
| 4lxk | 1YT | Beta-secretase 1 | 3.4.23.46 | 0.479 | |
| 4rnv | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.479 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.478 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.478 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.478 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.478 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.478 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.478 | |
| 4dx7 | DM2 | Multidrug efflux pump subunit AcrB | / | 0.478 | |
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 0.477 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.477 | |
| 2oah | QIN | Beta-secretase 1 | 3.4.23.46 | 0.477 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.477 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.477 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.477 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.477 | |
| 3t64 | DU3 | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.477 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.477 | |
| 3vg1 | 0GT | Beta-secretase 1 | 3.4.23.46 | 0.477 | |
| 4ef4 | C2E | Stimulator of interferon genes protein | / | 0.477 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.477 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.477 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.476 | |
| 1uxy | EPU | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.476 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.476 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.476 | |
| 2djl | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.476 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.476 | |
| 2r8o | T5X | Transketolase 1 | / | 0.476 | |
| 2wez | ZYE | Beta-secretase 1 | 3.4.23.46 | 0.476 | |
| 3e32 | ED2 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.476 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.476 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.476 | |
| 1nuq | NXX | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.475 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.475 | |
| 1owe | 675 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.475 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.475 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.475 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.475 | |
| 3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.475 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.475 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.475 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.475 | |
| 1dp2 | LPB | Thiosulfate sulfurtransferase | / | 0.474 | |
| 1evj | NAD | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.474 | |
| 1h6a | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.474 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.474 | |
| 1jue | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.474 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.474 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.474 | |
| 2vij | C44 | Beta-secretase 1 | 3.4.23.46 | 0.474 | |
| 2ylr | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.474 | |
| 4aws | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.474 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.474 | |
| 1d0l | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.473 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.473 | |
| 2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.473 | |
| 2hpv | FMN | FMN-dependent NADH-azoreductase | 1.7 | 0.473 | |
| 2viy | VG3 | Beta-secretase 1 | 3.4.23.46 | 0.473 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.473 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.473 | |
| 3ccc | 7AC | Dipeptidyl peptidase 4 | / | 0.473 | |
| 3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.473 | |
| 3s2v | 3HU | Glutamate receptor ionotropic, kainate 1 | / | 0.473 | |
| 3zmg | 6Z0 | Beta-secretase 1 | 3.4.23.46 | 0.473 | |
| 4bah | MEL | Prothrombin | 3.4.21.5 | 0.473 | |
| 4j0t | 6T9 | Beta-secretase 1 | 3.4.23.46 | 0.473 | |
| 1il0 | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.472 | |
| 1k9s | FM1 | Purine nucleoside phosphorylase DeoD-type | / | 0.472 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.472 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.472 | |
| 1omo | NAD | Alanine dehydrogenase | / | 0.472 | |
| 1qzy | TDE | Methionine aminopeptidase 2 | / | 0.472 | |
| 1xz8 | 5GP | Bifunctional protein PyrR | 2.4.2.9 | 0.472 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.472 | |
| 2a5h | SAM | L-lysine 2,3-aminomutase | 5.4.3.2 | 0.472 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.472 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.472 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.472 | |
| 3eks | CY9 | Actin-5C | / | 0.472 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.472 | |
| 4b1h | AR6 | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.472 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.472 | |
| 4gid | 0GH | Beta-secretase 1 | 3.4.23.46 | 0.472 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.472 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.472 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.472 | |
| 1ld7 | U66 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.471 | |
| 1o6z | NAD | Malate dehydrogenase | / | 0.471 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.471 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.471 | |
| 2ome | NAD | C-terminal-binding protein 2 | / | 0.471 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.471 | |
| 2qzl | IXS | Beta-secretase 1 | 3.4.23.46 | 0.471 | |
| 2vj6 | VG5 | Beta-secretase 1 | 3.4.23.46 | 0.471 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.471 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.471 | |
| 3muo | ZPR | Prolyl endopeptidase | / | 0.471 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.471 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.470 | |
| 1iki | REY | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.470 | |
| 1wzi | NDP | Malate dehydrogenase | / | 0.470 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.470 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.470 | |
| 2ii6 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.470 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.470 | |
| 2ydb | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.470 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.470 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.470 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.470 | |
| 3lkh | LT6 | Genome polyprotein | 2.7.7.48 | 0.470 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.470 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.470 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.470 | |
| 4nd4 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.470 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.470 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.469 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.469 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.469 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.469 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.469 | |
| 2fxu | BID | Actin, alpha skeletal muscle | / | 0.469 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.469 | |
| 3skg | PB8 | Beta-secretase 1 | 3.4.23.46 | 0.469 | |
| 3toz | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.469 | |
| 4dd8 | BAT | Disintegrin and metalloproteinase domain-containing protein 8 | 3.4.24 | 0.469 | |
| 4ge9 | 0L0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.469 | |
| 1dli | UDX | UDP-glucose 6-dehydrogenase | / | 0.468 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.468 | |
| 1sa5 | BMV | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.468 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.468 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.468 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.468 | |
| 2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
| 2zgb | 21U | Prothrombin | 3.4.21.5 | 0.468 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.468 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.468 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.468 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.468 | |
| 3vf3 | 0GS | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
| 4f6w | 0SS | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.468 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.468 | |
| 1dyh | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.467 | |
| 1kbi | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.467 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.467 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.467 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.467 | |
| 1zp4 | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.467 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.467 | |
| 2djx | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.467 | |
| 2ejz | SAH | Diphthine synthase | / | 0.467 | |
| 2emr | SAH | Diphthine synthase | / | 0.467 | |
| 2iib | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.467 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 2r8p | T6F | Transketolase 1 | / | 0.467 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.467 | |
| 3fvl | BHK | Carboxypeptidase A1 | 3.4.17.1 | 0.467 | |
| 3inr | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.467 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.467 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.467 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 4fdu | IHS | Putative multiple inositol polyphosphate histidine phosphatase 1 | / | 0.467 | |
| 4i10 | 1BS | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.467 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.467 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.466 | |
| 1juv | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.466 | |
| 1z41 | FMN | NADPH dehydrogenase | / | 0.466 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.466 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.466 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.466 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.466 | |
| 2oeg | UPG | UDP-glucose pyrophosphorylase | / | 0.466 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.466 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.466 | |
| 2xq0 | BES | Leukotriene A-4 hydrolase homolog | 3.3.2.6 | 0.466 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.466 | |
| 2yph | QQY | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.466 | |
| 3nt2 | NAD | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.466 | |
| 3opm | LUI | Dipeptidyl peptidase 4 | / | 0.466 | |
| 3pi5 | 3P5 | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
| 4jic | FMN | GTN Reductase | / | 0.466 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.466 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.466 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.465 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.465 | |
| 1mzc | BNE | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.465 | |
| 1u3c | FAD | Cryptochrome-1 | / | 0.465 | |
| 2bri | ANP | Uridylate kinase | 2.7.4.22 | 0.465 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.465 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.465 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 0.465 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.465 | |
| 3h0b | B35 | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.465 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.465 | |
| 4emt | C2E | Stimulator of interferon genes protein | / | 0.465 | |
| 4xbj | IN5 | Alanine racemase, biosynthetic | / | 0.465 | |
| 4yj2 | GTP | Tubulin alpha-1B chain | / | 0.465 | |
| 1h65 | GDP | Translocase of chloroplast 34 | 3.6.5 | 0.464 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.464 | |
| 1t3z | CAO | Formyl-CoA:oxalate CoA-transferase | / | 0.464 | |
| 1v45 | 3DG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.464 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.464 | |
| 2wvm | GDD | Mannosyl-3-phosphogylcerate synthase | / | 0.464 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.464 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.464 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.464 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.464 | |
| 3isj | A8D | Pantothenate synthetase | 6.3.2.1 | 0.464 | |
| 3ivg | FG5 | Pantothenate synthetase | 6.3.2.1 | 0.464 | |
| 3ixk | 929 | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 3uxv | GUN | NADPH-dependent 7-cyano-7-deazaguanine reductase | / | 0.464 | |
| 3w2e | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.464 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.464 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.464 | |
| 4bao | MVF | Prothrombin | 3.4.21.5 | 0.464 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.464 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.464 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.464 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.464 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.464 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.464 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.464 | |
| 4kc4 | WS3 | Histo-blood group ABO system transferase | / | 0.464 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.463 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.463 | |
| 2cbr | A80 | Cellular retinoic acid-binding protein 1 | / | 0.463 | |
| 2flh | ZEA | Cytokinin-specific binding protein | / | 0.463 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.463 | |
| 3fpj | SAM | Uncharacterized protein | / | 0.463 | |
| 3fql | 79Z | Genome polyprotein | 2.7.7.48 | 0.463 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.463 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 3ohf | 3HF | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.463 | |
| 3v2b | AR6 | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.463 | |
| 4i0h | 1BL | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.463 | |
| 4la1 | FAD | Thioredoxin glutathione reductase | / | 0.463 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.463 | |
| 4pzs | ACO | Histone acetyltransferase p300 | / | 0.463 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.463 | |
| 1ni1 | 2C5 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.462 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.462 | |
| 1vji | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.462 | |
| 1zdw | FLV | Prenyltransferase | / | 0.462 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.462 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.462 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 2d4v | NAD | Isocitrate dehydrogenase [NADP] | / | 0.462 | |
| 2owf | SAH | Diphthine synthase | / | 0.462 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.462 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.462 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.462 | |
| 3bmo | NAP | Pteridine reductase | / | 0.462 | |
| 3g0b | T22 | Dipeptidyl peptidase 4 | / | 0.462 | |
| 3k5g | BJC | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.462 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.462 | |
| 3veu | 0GO | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 3zcb | ATP | Adenosine monophosphate-protein transferase VbhT | 2.7.7.n1 | 0.462 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.462 | |
| 4bqz | GNP | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.462 | |
| 4dpi | 0N1 | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 4ef9 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.462 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.462 | |
| 4f9g | C2E | Stimulator of interferon genes protein | / | 0.462 | |
| 4fm8 | 0UQ | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 4gcm | NAP | Thioredoxin reductase | 1.8.1.9 | 0.462 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.462 | |
| 4zwm | PLP | Ornithine aminotransferase, mitochondrial, putative | / | 0.462 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.461 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.461 | |
| 1ib6 | NAD | Malate dehydrogenase | / | 0.461 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.461 | |
| 1kvu | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.461 | |
| 1nqw | 5YL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.461 | |
| 1tys | DHF | Thymidylate synthase | / | 0.461 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.461 | |
| 2g94 | ZPQ | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 2wf1 | ZY1 | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.461 | |
| 3dm6 | 757 | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 3exo | 5MS | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 3jyq | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.461 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.461 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.461 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.461 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.461 | |
| 4e32 | DWN | Methyltransferase | / | 0.461 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.461 | |
| 4exg | 916 | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.461 | |
| 4rel | KMP | Glycosyltransferase | / | 0.461 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.460 | |
| 1j0x | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.460 | |
| 1je1 | GMP | Purine nucleoside phosphorylase | / | 0.460 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.460 | |
| 1tys | TMP | Thymidylate synthase | / | 0.460 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.460 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.460 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.460 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.460 | |
| 2f99 | AKV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.460 | |
| 2fdp | FRP | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 2fiw | ACO | GCN5-related N-acetyltransferase:Aminotransferase, class-II | / | 0.460 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.460 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.460 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 2wzw | NDP | Nitroreductase NfnB | / | 0.460 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.460 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.460 | |
| 3ksq | Z96 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.460 | |
| 3sxj | SAM | Putative methyltransferase | / | 0.460 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.460 | |
| 3tqx | PLP | 2-amino-3-ketobutyrate coenzyme A ligase | / | 0.460 | |
| 3udk | 095 | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 3vil | SA0 | Beta-glucosidase | / | 0.460 | |
| 3vjl | W94 | Dipeptidyl peptidase 4 | / | 0.460 | |
| 4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.460 | |
| 4ddh | MS0 | Pantothenate synthetase | 6.3.2.1 | 0.460 | |
| 4e2b | FMN | Dehydrogenase | / | 0.460 | |
| 4fri | DWA | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 4loi | 1YC | Stimulator of interferon genes protein | / | 0.460 | |
| 4rh1 | 0TT | Spore photoproduct lyase | / | 0.460 | |
| 4rvd | SAM | D-mycarose 3-C-methyltransferase | / | 0.460 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.460 | |
| 4xfj | ANP | Argininosuccinate synthase | / | 0.460 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.460 | |
| 4djh | JDC | Kappa-type opioid receptor | / | 0.460 | |
| 1lc3 | NAD | Biliverdin reductase A | 1.3.1.24 | 0.459 | |
| 1m8k | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.459 | |
| 1mbb | EEB | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.459 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.459 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 1wze | NAD | Malate dehydrogenase | / | 0.459 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.459 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.459 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.459 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.459 | |
| 2z3n | PHE_ARG_TYR_LEU_GLY | Leucyl/phenylalanyl-tRNA--protein transferase | 2.3.2.6 | 0.459 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.459 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 3e23 | SAM | Uncharacterized protein | / | 0.459 | |
| 3klb | FMN | Uncharacterized protein | / | 0.459 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.459 | |
| 4awt | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.459 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.459 | |
| 4ikz | AFS | Di-tripeptide ABC transporter (Permease) | / | 0.459 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.459 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.459 | |
| 4yqf | GDP | Septin-9 | / | 0.459 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.459 | |
| 1a8r | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.458 | |
| 1d4d | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.458 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.458 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.458 | |
| 1ri3 | SAH | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.458 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 1vhz | APR | ADP compounds hydrolase NudE | 3.6.1 | 0.458 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.458 | |
| 2b4r | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.458 | |
| 2fa3 | ACO | Hydroxymethylglutaryl-CoA synthase | / | 0.458 | |
| 2p9g | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.458 | |
| 2r5n | TPP | Transketolase 1 | / | 0.458 | |
| 3daa | PDD | D-alanine aminotransferase | 2.6.1.21 | 0.458 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.458 | |
| 3int | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.458 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.458 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.458 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 4blr | UTP | NTPase P4 | / | 0.458 | |
| 4y3j | HIC | Endothiapepsin | 3.4.23.22 | 0.458 | |
| 5dw5 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.458 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.458 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.457 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.457 | |
| 1h8h | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.457 | |
| 1h8h | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.457 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.457 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.457 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.457 | |
| 2gmv | PEP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.457 | |
| 2hu2 | NAD | C-terminal binding protein 1 | / | 0.457 | |
| 2p0r | LEU_LEU_ACE_AR7 | Calpain-9 | / | 0.457 | |
| 3duy | AFJ | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 3g0d | XIH | Dipeptidyl peptidase 4 | / | 0.457 | |
| 3g0g | RUM | Dipeptidyl peptidase 4 | / | 0.457 | |
| 3kkz | SAM | Uncharacterized protein | / | 0.457 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.457 | |
| 3r2f | PB0 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.457 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.457 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.457 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.456 | |
| 1jdv | ADN | Purine nucleoside phosphorylase | / | 0.456 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.456 | |
| 1w4x | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.456 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.456 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.456 | |
| 2hm1 | LIQ | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.456 | |
| 2jkv | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.456 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.456 | |
| 2pci | SAH | Diphthine synthase | / | 0.456 | |
| 2xb9 | XNW | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.456 | |
| 2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.456 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.456 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.456 | |
| 3tnl | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.456 | |
| 3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.456 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.456 | |
| 4da0 | GNG | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.456 | |
| 4dpf | 0LG | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 4img | NGF | N-acetylneuraminate lyase | / | 0.456 | |
| 4jiq | 1L5 | GTN Reductase | / | 0.456 | |
| 4jzr | 4JR | Egl nine homolog 1 | / | 0.456 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.456 | |
| 4m0c | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.456 | |
| 4tln | LNO | Thermolysin | 3.4.24.27 | 0.456 | |
| 4yfy | 0FX | VioF | / | 0.456 | |
| 4zu4 | 4TG | WxcM-like protein | / | 0.456 | |
| 5b0o | ADP | Flagellum-specific ATP synthase | 3.6.3.14 | 0.456 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.455 | |
| 1jdt | MTA | Purine nucleoside phosphorylase | / | 0.455 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.455 | |
| 1r6t | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.455 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.455 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.455 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 2g20 | L1A | Renin | 3.4.23.15 | 0.455 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.455 | |
| 2ntr | L00 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 2std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.455 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 2wya | HMG | Hydroxymethylglutaryl-CoA synthase, mitochondrial | 2.3.3.10 | 0.455 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.455 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.455 | |
| 3eku | CY9 | Actin-5C | / | 0.455 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.455 | |
| 3h2s | NDP | Putative NADH-flavin reductase | / | 0.455 | |
| 3o0q | ADN | Vitamin B12-dependent ribonucleotide reductase | / | 0.455 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.455 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.455 | |
| 4afg | QMR | Achbp | / | 0.455 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.455 | |
| 4fco | 0U4 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.455 | |
| 4hmx | FMN | Pyridoxamine 5'-phosphate oxidase | / | 0.455 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.455 | |
| 1get | FAD | Glutathione reductase | 1.8.1.7 | 0.454 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.454 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.454 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.454 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.454 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.454 | |
| 1xkv | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.454 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.454 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.454 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.454 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 2vou | FAD | 2,6-dihydroxypyridine 3-monooxygenase | 1.14.13.10 | 0.454 | |
| 2wp9 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.454 | |
| 2wp9 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.454 | |
| 2xvh | NAP | Putative flavin-containing monooxygenase | / | 0.454 | |
| 2zrx | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.454 | |
| 3kej | 3EJ | Collagenase 3 | 3.4.24 | 0.454 | |
| 3l5l | FMN | Xenobiotic reductase | / | 0.454 | |
| 3n14 | FMN | Xenobiotic reductase | / | 0.454 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4djx | 0KQ | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4hyv | PEP | Pyruvate kinase 1 | 2.7.1.40 | 0.454 | |
| 4j75 | TYM | Tryptophan--tRNA ligase | / | 0.454 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.454 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.454 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.454 | |
| 1daa | PLP | D-alanine aminotransferase | 2.6.1.21 | 0.453 | |
| 1h6c | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.453 | |
| 1qf4 | RPD | Adenylosuccinate synthetase | / | 0.453 | |
| 2ckm | AA7 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 2f3f | AXF | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 2tmn | 0FA | Thermolysin | 3.4.24.27 | 0.453 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.453 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.453 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.453 | |
| 3dme | FAD | Putative conserved exported protein | / | 0.453 | |
| 3e8x | NAP | BH1520 protein | / | 0.453 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.453 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 3qgi | 33F | Genome polyprotein | 2.7.7.48 | 0.453 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.453 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.453 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.453 | |
| 4da6 | GA2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.453 | |
| 4dro | 0MD | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.453 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 4i4b | 1CV | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.453 | |
| 4lnb | ED5 | CaaX farnesyltransferase beta subunit Ram1 | / | 0.453 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.453 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.453 | |
| 5c41 | ACP | Ribokinase | / | 0.453 | |
| 5e7o | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.453 | |
| 6tmn | 0PI | Thermolysin | 3.4.24.27 | 0.453 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.452 | |
| 1fcb | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.452 | |
| 1ghv | 120 | Prothrombin | 3.4.21.5 | 0.452 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.452 | |
| 2a2d | ANP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.452 | |
| 2anb | 5GP | Guanylate kinase | 2.7.4.8 | 0.452 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2daa | DCS | D-alanine aminotransferase | 2.6.1.21 | 0.452 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.452 | |
| 2ooy | ATP | 5'-AMP-activated protein kinase subunit gamma | / | 0.452 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.452 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.452 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 3bbd | SAH | Ribosomal RNA small subunit methyltransferase Nep1 | 2.1.1 | 0.452 | |
| 3beo | UD1 | UDP-N-acetylglucosamine 2-epimerase | / | 0.452 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.452 | |
| 3c3e | GDP | 2-phospho-L-lactate transferase | / | 0.452 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.452 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.452 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.452 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.452 | |
| 3hnz | PMN | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.452 | |
| 3ieu | GDP | GTPase Era | / | 0.452 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.452 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.452 | |
| 3ou2 | SAH | SAM-dependent methyltransferase | / | 0.452 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.452 | |
| 4du6 | GTP | GTP cyclohydrolase 1 | / | 0.452 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.452 | |
| 4f5y | C2E | Stimulator of interferon genes protein | / | 0.452 | |
| 4g67 | SAH | Uncharacterized ACR, COG1565 superfamily | / | 0.452 | |
| 4gdd | FAD | UDP-galactopyranose mutase | / | 0.452 | |
| 4j4n | D44 | Peptidylprolyl isomerase | / | 0.452 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.452 | |
| 4qxr | 1YE | Stimulator of interferon genes protein | / | 0.452 | |
| 5ch7 | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.452 | |
| 1d2h | SAH | Glycine N-methyltransferase | 2.1.1.20 | 0.451 | |
| 1ges | FAD | Glutathione reductase | 1.8.1.7 | 0.451 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.451 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.451 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.451 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.451 | |
| 2e9d | B76 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.451 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.451 | |
| 2f3e | AXQ | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.451 | |
| 2rdn | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.451 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.451 | |
| 2zhw | 12U | Prothrombin | 3.4.21.5 | 0.451 | |
| 2ztu | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.451 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.451 | |
| 3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.451 | |
| 3s87 | ADP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.451 | |
| 3wcz | NAP | Aldo-keto reductase AKR2E4 | / | 0.451 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.451 | |
| 4b65 | NDP | L-ornithine N(5)-monooxygenase | / | 0.451 | |
| 4jfi | 1KT | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.451 | |
| 4z0p | NDP | NAD-dependent dehydrogenase | / | 0.451 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.451 | |
| 3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.451 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.450 | |
| 1hi0 | GTP | RNA-directed RNA polymerase | 2.7.7.48 | 0.450 | |
| 1i5e | U5P | Uracil phosphoribosyltransferase | / | 0.450 | |
| 1j1z | ATP | Argininosuccinate synthase | / | 0.450 | |
| 1kr2 | TAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.450 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.450 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.450 | |
| 1qpl | 587 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.450 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.450 | |
| 1v0j | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.450 | |
| 1ypj | UIB | Prothrombin | 3.4.21.5 | 0.450 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.450 | |
| 2dsg | SAH | Diphthine synthase | / | 0.450 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.450 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.450 | |
| 2ph6 | 712 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.450 | |
| 2vkv | TDC | Tetracycline repressor protein class D | / | 0.450 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.450 | |
| 2xy3 | DUP | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.450 | |
| 2zr9 | DTP | Protein RecA | / | 0.450 | |
| 2zue | ANP | Arginine--tRNA ligase | 6.1.1.19 | 0.450 | |
| 2zz0 | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.450 | |
| 3e6e | DCS | Alanine racemase | / | 0.450 | |
| 3e6y | CW1 | 14-3-3-like protein C | / | 0.450 | |
| 3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.450 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.450 | |
| 3kmx | G00 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3lzs | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 3pka | Y02 | Methionine aminopeptidase 2 | / | 0.450 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.450 | |
| 4wrk | DUP | DUTPase | / | 0.450 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.450 | |
| 1aka | PLP | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.449 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.449 | |
| 1f0x | FAD | D-lactate dehydrogenase | 1.1.1.28 | 0.449 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.449 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 1k4m | NAD | Nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.449 | |
| 1ky2 | GNP | GTP-binding protein YPT7 | / | 0.449 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.449 | |
| 1nvm | NAD | Acetaldehyde dehydrogenase | 1.2.1.10 | 0.449 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1xnj | ADP | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | 2.7.1.25 | 0.449 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.449 | |
| 2ex1 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.449 | |
| 2fr1 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.449 | |
| 2gou | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.449 | |
| 2gyw | OBI | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 2wf4 | ZY4 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.449 | |
| 3eq0 | 2TS | Prothrombin | 3.4.21.5 | 0.449 | |
| 3hyg | 099 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.449 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.449 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3pkb | Y16 | Methionine aminopeptidase 2 | / | 0.449 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.449 | |
| 3u9e | COA | Lmo1369 protein | / | 0.449 | |
| 3vax | PLP | Uncharacterized protein | / | 0.449 | |
| 4clo | NAP | Pteridine reductase | / | 0.449 | |
| 4f6r | GDP | Tubulin beta chain | / | 0.449 | |
| 4fkz | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.449 | |
| 4flk | Y10 | Methionine aminopeptidase 1 | / | 0.449 | |
| 4h80 | 04T | Aldehyde dehydrogenase, dimeric NADP-preferring | / | 0.449 | |
| 4hmw | FMN | Pyridoxamine 5'-phosphate oxidase | / | 0.449 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.449 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.449 | |
| 4xr9 | NAD | CalS8 | / | 0.449 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.449 | |
| 1a5b | IGP | Tryptophan synthase alpha chain | / | 0.448 | |
| 1fdr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.448 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.448 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.448 | |
| 1hku | NAD | C-terminal-binding protein 1 | 1.1.1 | 0.448 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.448 | |
| 1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.448 | |
| 1nl4 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.448 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.448 | |
| 1x27 | ASP_ASP_TYR_VAL_PTR | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.448 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.448 | |
| 2emu | SAH | Diphthine synthase | / | 0.448 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.448 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.448 | |
| 2ok8 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.448 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.448 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.448 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.448 | |
| 2z3l | PHE_ARG_TYR_LEU_GLY | Leucyl/phenylalanyl-tRNA--protein transferase | 2.3.2.6 | 0.448 | |
| 3ai0 | PNW | Beta-glucosidase | / | 0.448 | |
| 3b9x | NOS | Pyrimidine-specific ribonucleoside hydrolase RihB | 3.2.2.8 | 0.448 | |
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 | / | 0.448 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.448 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3iqg | ASN_TRP_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.448 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.448 | |
| 3mj4 | URM | UDP-galactopyranose mutase | / | 0.448 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.448 | |
| 3o5r | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.448 | |
| 3r43 | ID8 | Aldo-keto reductase family 1 member C3 | / | 0.448 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.448 | |
| 4drn | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.448 | |
| 4k81 | GTP | GTPase HRas | / | 0.448 | |
| 4k8s | 1QT | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4l4x | NDP | AmphI | / | 0.448 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.448 | |
| 4xo7 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.448 | |
| 4yek | THM | Thymidine phosphorylase | / | 0.448 | |
| 1ahg | TYR_PLP | Aspartate aminotransferase | 2.6.1.1 | 0.447 | |
| 1b5e | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.447 | |
| 1bux | PPS | Nucleoside diphosphate kinase, cytosolic | 2.7.4.6 | 0.447 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.447 | |
| 1pw1 | HEL | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.447 | |
| 1sa4 | JAN | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.447 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.447 | |
| 2bkj | FMN | NADPH-flavin oxidoreductase | / | 0.447 | |
| 2c9b | PUG | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.447 | |
| 2e8r | SAH | Diphthine synthase | / | 0.447 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.447 | |
| 2eeq | SAH | Diphthine synthase | / | 0.447 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.447 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.447 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.447 | |
| 2i3g | NAP | N-acetyl-gamma-glutamyl-phosphate reductase | 1.2.1.38 | 0.447 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.447 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.447 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2p6k | SAH | Diphthine synthase | / | 0.447 | |
| 2q14 | ADP | Phosphohydrolase | / | 0.447 | |
| 2qc8 | ADP | Glutamine synthetase | 6.3.1.2 | 0.447 | |
| 2v2z | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.447 | |
| 2v7q | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.447 | |
| 2v7q | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.447 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.447 | |
| 3e33 | ED7 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.447 | |
| 3gwd | NAP | Cyclohexanone monooxygenase | / | 0.447 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.447 | |
| 3p80 | P80 | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 3qfa | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.447 | |
| 3r96 | ACO | MccE protein | / | 0.447 | |
| 3ske | 054 | Genome polyprotein | 2.7.7.48 | 0.447 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.447 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.447 | |
| 3zcn | ATP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.447 | |
| 3zid | GDP | Tubulin-like protein CetZ | / | 0.447 | |
| 4jwp | ACO | GCN5-related N-acetyltransferase | / | 0.447 | |
| 4lol | 1YE | Stimulator of interferon genes protein | / | 0.447 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.447 | |
| 5bqf | NAP | Probable hydroxyacid dehydrogenase protein | / | 0.447 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.447 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.446 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.446 | |
| 1bx1 | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.446 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.446 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1snf | UMP | Deoxyuridine 5'-triphosphate nucleotidohydrolase | 3.6.1.23 | 0.446 | |
| 1uay | ADN | Oxidoreductase | / | 0.446 | |
| 1wng | SAH | Diphthine synthase | / | 0.446 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.446 | |
| 2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.446 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.446 | |
| 2e4n | SAH | Diphthine synthase | / | 0.446 | |
| 2hp2 | KE4 | Glutamate-1-semialdehyde 2,1-aminomutase | 5.4.3.8 | 0.446 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.446 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.446 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.446 | |
| 2wat | COA | Fatty acid synthase subunit alpha | 2.3.1.86 | 0.446 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 3i25 | MV7 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.446 | |
| 3ihz | FK5 | Peptidylprolyl isomerase | / | 0.446 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.446 | |
| 3k5f | AYH | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3l5b | BDO | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3q70 | RIT | Candidapepsin-2 | 3.4.23.24 | 0.446 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.446 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.446 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.446 | |
| 4buu | F38 | Tankyrase-2 | 2.4.2.30 | 0.446 | |
| 4c0b | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.446 | |
| 4c13 | UML | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase | / | 0.446 | |
| 4fnc | HMU | G/T mismatch-specific thymine DNA glycosylase | 3.2.2.29 | 0.446 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.446 | |
| 4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.446 | |
| 4i9h | 1E4 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.446 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.446 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.446 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.446 | |
| 4tqg | NDP | Putative dTDP-d-glucose 4 6-dehydratase | / | 0.446 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.446 | |
| 4yp6 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.446 | |
| 5c2t | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.446 | |
| 5dbg | NAD | Iridoid synthase | 1.3.1.99 | 0.446 | |
| 1a59 | COA | 2-methylcitrate synthase | / | 0.445 | |
| 1a9c | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.445 | |
| 1eyy | NAP | NADP-dependent fatty aldehyde dehydrogenase | 1.2.1.4 | 0.445 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.445 | |
| 1i6k | TYM | Tryptophan--tRNA ligase | 6.1.1.2 | 0.445 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.445 | |
| 1mok | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.445 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.445 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.445 | |
| 1nfy | RTR | Coagulation factor X | 3.4.21.6 | 0.445 | |
| 1owd | 497 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.445 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.445 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.445 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.445 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.445 | |
| 2hux | SAH | Diphthine synthase | / | 0.445 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.445 | |
| 2r6g | ATP | Maltose/maltodextrin import ATP-binding protein MalK | / | 0.445 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.445 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.445 | |
| 3k5d | XLI | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.445 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.445 | |
| 3mje | NDP | AmphB | / | 0.445 | |
| 3pft | FMN | Flavin reductase | / | 0.445 | |
| 3tjl | FMN | NADPH dehydrogenase | / | 0.445 | |
| 3uyk | 0CX | Probable NDP-rhamnosyltransferase | / | 0.445 | |
| 3v2u | ATP | Protein GAL3 | / | 0.445 | |
| 3v4e | COA | Putative acetyltransferase SACOL2570 | 2.3.1 | 0.445 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.445 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.445 | |
| 4d04 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.445 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.445 | |
| 4isk | 1JY | Thymidylate synthase | / | 0.445 | |
| 4lut | DCS | Alanine racemase | / | 0.445 | |
| 4wso | NAD | Probable nicotinate-nucleotide adenylyltransferase | / | 0.445 | |
| 4yjd | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.445 | |
| 5a01 | 12V | O-glycosyltransferase | / | 0.445 | |
| 5di3 | GNP | ADP-ribosylation factor-like protein 3 | / | 0.445 | |
| 5la6 | GDP | Tubulin beta-2B chain | / | 0.445 | |
| 1cbq | RE9 | Cellular retinoic acid-binding protein 2 | / | 0.444 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.444 | |
| 1n95 | FTH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.444 | |
| 1o1s | 1NH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.444 | |
| 1oxo | IK2 | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.444 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.444 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.444 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.444 | |
| 1ta2 | 176 | Prothrombin | 3.4.21.5 | 0.444 | |
| 1yqd | NAP | Sinapyl alcohol dehydrogenase | / | 0.444 | |
| 2b3v | ACO | Diamine acetyltransferase 1 | / | 0.444 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.444 | |
| 2en5 | SAH | Diphthine synthase | / | 0.444 | |
| 2ge3 | ACO | Probable acetyltransferase | / | 0.444 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.444 | |
| 2vjm | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.444 | |
| 2wjo | QUD | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2zff | 53U | Prothrombin | 3.4.21.5 | 0.444 | |
| 3a37 | ADP | ATPase GET3 | / | 0.444 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.444 | |
| 3ccb | B2Y | Dipeptidyl peptidase 4 | / | 0.444 | |
| 3dk8 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.444 | |
| 3gwd | FAD | Cyclohexanone monooxygenase | / | 0.444 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.444 | |
| 3mkn | DNB | Pyrimidine-specific ribonucleoside hydrolase RihB | / | 0.444 | |
| 3p4t | FAO | Putative acyl-CoA dehydrogenase | / | 0.444 | |
| 3qto | 10P | Prothrombin | 3.4.21.5 | 0.444 | |
| 3w1q | YRO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.444 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 4djw | 0KP | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4drp | 0MD | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.444 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.444 | |
| 4ewo | 996 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4fl0 | PLP | Aminotransferase ALD1, chloroplastic | 2.6.1 | 0.444 | |
| 4h12 | SAH | Histone-lysine N-methyltransferase SETD2 | 2.1.1.43 | 0.444 | |
| 4i4z | 2NE | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.444 | |
| 4j7g | TRH | PCZA361.3 | / | 0.444 | |
| 4mkh | AP5 | Adenylate kinase | / | 0.444 | |
| 4na4 | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.444 | |
| 4rnw | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.444 | |
| 4tmb | FMN | Old yellow enzyme | / | 0.444 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.444 | |
| 5c4n | NAP | Precorrin-6A reductase | 1.3.1.54 | 0.444 | |
| 5e7o | MGD | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.444 | |
| 5itz | LOC | Tubulin beta-2B chain | / | 0.444 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.443 | |
| 1i9c | 5AD | Glutamate mutase epsilon subunit | / | 0.443 | |
| 1j0d | 5PA | 1-aminocyclopropane-1-carboxylate deaminase | 3.5.99.7 | 0.443 | |
| 1njf | ADP | DNA polymerase III subunit tau | 2.7.7.7 | 0.443 | |
| 1qcw | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.443 | |
| 1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.443 | |
| 1ra8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1vg8 | GNP | Ras-related protein Rab-7a | / | 0.443 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.443 | |
| 2b3d | FAD | Modulator of drug activity B | / | 0.443 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.443 | |
| 2ek4 | SAH | Diphthine synthase | / | 0.443 | |
| 2ob0 | ACO | N-alpha-acetyltransferase 50 | / | 0.443 | |
| 2p8h | MY9 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 2wf2 | ZY2 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.443 | |
| 2yj4 | ATP | Copper-transporting ATPase | / | 0.443 | |
| 2zhq | 27U | Prothrombin | 3.4.21.5 | 0.443 | |
| 2znk | 31U | Prothrombin | 3.4.21.5 | 0.443 | |
| 3cwq | ADP | ParA family chromosome partitioning protein | / | 0.443 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 3nh8 | DC2 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) | 3.5.1.114 | 0.443 | |
| 3o7b | SAH | Ribosomal RNA small subunit methyltransferase Nep1 | / | 0.443 | |
| 3uaw | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.443 | |
| 4ask | K0I | Lysine-specific demethylase 6B | 1.14.11 | 0.443 | |
| 4b05 | 32D | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.443 | |
| 4drk | I63 | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.443 | |
| 4e2w | JHZ | Methyltransferase | / | 0.443 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.443 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.443 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.443 | |
| 4mfe | BTN | Pyruvate carboxylase | / | 0.443 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.443 | |
| 4nxx | GDP | Mitochondrial dynamics protein MID51 | / | 0.443 | |
| 4q4k | FMN | Uncharacterized protein | / | 0.443 | |
| 4qi7 | FAD | Cellobiose dehydrogenase | / | 0.443 | |
| 4rv9 | SAH | D-mycarose 3-C-methyltransferase | / | 0.443 | |
| 4s1i | PLP | Pyridoxal kinase, putative | / | 0.443 | |
| 4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 4y9q | C2E | Uncharacterized protein | / | 0.443 | |
| 3uon | QNB | Muscarinic acetylcholine receptor M2 | / | 0.443 | |
| 1dfo | FFO | Serine hydroxymethyltransferase | 2.1.2.1 | 0.442 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.442 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1ha3 | MAU | Elongation factor Tu-A | / | 0.442 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1i5c | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.442 | |
| 1i6x | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.442 | |
| 1mmk | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.442 | |
| 1ny2 | ARG_PRO_PRO_GLY | Prothrombin | 3.4.21.5 | 0.442 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.442 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.442 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.442 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.442 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.442 | |
| 1vgq | CAO | Formyl-CoA:oxalate CoA-transferase | / | 0.442 | |
| 2d8a | NAD | L-threonine 3-dehydrogenase | / | 0.442 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.442 | |
| 2vq7 | NAP | Putative flavin-containing monooxygenase | / | 0.442 | |
| 2xfy | ACX | Beta-amylase | 3.2.1.2 | 0.442 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.442 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.442 | |
| 3enk | UPG | UDP-glucose 4-epimerase | / | 0.442 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.442 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.442 | |
| 3giy | FMN | (S)-mandelate dehydrogenase | 1.1.99.31 | 0.442 | |
| 3h86 | AP5 | Adenylate kinase | / | 0.442 | |
| 3ioe | A7D | Pantothenate synthetase | 6.3.2.1 | 0.442 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.442 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.442 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.442 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.442 | |
| 3qbj | NXZ | Dipeptidyl peptidase 4 | / | 0.442 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.442 | |
| 3tyc | XHP | Dihydropteroate synthase | / | 0.442 | |
| 3vye | VYE | Renin | 3.4.23.15 | 0.442 | |
| 3wqu | ATP | Cell division protein FtsA | / | 0.442 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.442 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.442 | |
| 4gtv | 7TR | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.442 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.442 | |
| 4i0b | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.442 | |
| 4ike | ADP | Adenylate kinase | / | 0.442 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 4xo7 | ASD | Aldo-keto reductase family 1 member C2 | / | 0.442 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.442 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.442 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.441 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1dyi | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.441 | |
| 1kw8 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.441 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.441 | |
| 1y56 | FAD | 382aa long hypothetical sarcosine oxidase | / | 0.441 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.441 | |
| 2d3a | ADP | Glutamine synthetase root isozyme 3 | 6.3.1.2 | 0.441 | |
| 2dgn | DOI | Adenylosuccinate synthetase isozyme 1 | / | 0.441 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.441 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.441 | |
| 2gna | GDU | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.441 | |
| 2ixk | TDO | dTDP-4-dehydrorhamnose 3,5-epimerase | 5.1.3.13 | 0.441 | |
| 2o3u | NGD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.441 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.441 | |
| 2viz | VG4 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.441 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2ylt | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.441 | |
| 2zsb | ADP | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
| 3koy | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.441 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.441 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.441 | |
| 3nut | SAH | Precorrin-3 methylase | / | 0.441 | |
| 3p17 | 99P | Prothrombin | 3.4.21.5 | 0.441 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 3pmy | 41L | Endothiapepsin | 3.4.23.22 | 0.441 | |
| 3ppr | 4CS | Glycine betaine/carnitine/choline-binding protein OpuCC | / | 0.441 | |
| 3px3 | T3Q | dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase | 2.1.1.235 | 0.441 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3t4h | MD5 | Alpha-ketoglutarate-dependent dioxygenase AlkB | 1.14.11.33 | 0.441 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.441 | |
| 4bf9 | FMN | tRNA-dihydrouridine(16) synthase | / | 0.441 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.441 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.441 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4k36 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.441 | |
| 4qbg | AP5 | Adenylate kinase | / | 0.441 | |
| 4uoc | NCN | CinA-like protein | / | 0.441 | |
| 5k7w | SAH | N6-adenosine-methyltransferase 70 kDa subunit | / | 0.441 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.440 | |
| 1gtr | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.440 | |
| 1kbj | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.440 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.440 | |
| 1ld8 | U49 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.440 | |
| 1n2h | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.440 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 1x2e | ATX | Proline iminopeptidase | 3.4.11.5 | 0.440 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.440 | |
| 2cda | NAP | Glucose 1-dehydrogenase | / | 0.440 | |
| 2cmo | M1L | Glutamate receptor 2 | / | 0.440 | |
| 2e1z | B4P | Propionate kinase | / | 0.440 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.440 | |
| 2g76 | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.440 | |
| 2gs9 | SAH | Uncharacterized protein | / | 0.440 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.440 | |
| 2r2n | KYN | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.440 | |
| 2uuj | 896 | Prothrombin | 3.4.21.5 | 0.440 | |
| 2v8p | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.440 | |
| 2wb2 | FAD | RE11660p | / | 0.440 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 | |
| 2ywl | FAD | Thioredoxin reductase related protein | / | 0.440 | |
| 2zu8 | GDD | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.440 | |
| 3ag6 | PAJ | Pantothenate synthetase | / | 0.440 | |
| 3axk | NDP | Ribulose bisphosphate carboxylase large chain | 4.1.1.39 | 0.440 | |
| 3b28 | B2X | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.440 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.440 | |
| 3bnk | FMN | Flavoredoxin | / | 0.440 | |
| 3bur | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 3clr | FAD | Electron transfer flavoprotein subunit alpha | / | 0.440 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 3ho9 | N3A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.440 | |
| 3kb6 | NAD | D-lactate dehydrogenase | / | 0.440 | |
| 3m4p | 4AD | Asparaginyl-tRNA synthetase, putative | / | 0.440 | |
| 3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.440 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 4a31 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4bk2 | FAD | Probable salicylate monooxygenase | / | 0.440 | |
| 4brd | ANP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.440 | |
| 4c1e | MCO | Beta-lactamase class B VIM-2 | / | 0.440 | |
| 4dzz | ADP | Plasmid partitioning protein ParF | / | 0.440 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4h57 | 0PJ | Thermolysin | 3.4.24.27 | 0.440 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.440 | |
| 4z26 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.440 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.440 | |
| 5itz | GTP | Tubulin alpha-1B chain | / | 0.440 | |
| 7kme | ACE_0BN_CHG_PRR | Prothrombin | 3.4.21.5 | 0.440 |