2.450 Å
X-ray
2008-08-06
Name: | Protein farnesyltransferase subunit beta |
---|---|
ID: | FNTB_RAT |
AC: | Q02293 |
Organism: | Rattus norvegicus |
Reign: | Eukaryota |
TaxID: | 10116 |
EC Number: | 2.5.1.58 |
Chain Name: | Percentage of Residues within binding site |
---|---|
A | 8 % |
B | 92 % |
B-Factor: | 21.694 |
---|---|
Number of residues: | 23 |
Including | |
Standard Amino Acids: | 22 |
Non Standard Amino Acids: | 1 |
Water Molecules: | 0 |
Cofactors: | |
Metals: | ZN |
Ligandability | Volume (Å3) |
---|---|
0.408 | 705.375 |
% Hydrophobic | % Polar |
---|---|
37.80 | 62.20 |
According to VolSite |
HET Code: | ED2 |
---|---|
Formula: | C25H27N7O2S |
Molecular weight: | 489.593 g/mol |
DrugBank ID: | - |
Buried Surface Area: | 55.38 % |
Polar Surface area: | 108.42 Å2 |
Number of | |
---|---|
H-Bond Acceptors: | 6 |
H-Bond Donors: | 0 |
Rings: | 4 |
Aromatic rings: | 4 |
Anionic atoms: | 0 |
Cationic atoms: | 0 |
Rule of Five Violation: | 0 |
Rotatable Bonds: | 10 |
X | Y | Z |
---|---|---|
52.9037 | -50.5254 | 3.63986 |
Represent the protein/ligand binding mode, centered on the ligand
Dashed lines represents hydrogen bonds and metal interactions
Green residue labels for amino acids with hydrophobic contacts (green lines) to the ligand
Ligand | Protein | Interaction | |||
---|---|---|---|---|---|
Atom | Atom | Residue | Distance (Å) | Angle (°) | Type |
CAI | CD2 | LEU- 96 | 4.04 | 0 | Hydrophobic |
CAL | CD1 | LEU- 96 | 4.27 | 0 | Hydrophobic |
CAG | CB | SER- 99 | 4.37 | 0 | Hydrophobic |
OAD | OH | TYR- 361 | 3.42 | 129.43 | H-Bond (Protein Donor) |
CAZ | CB | TYR- 361 | 3.33 | 0 | Hydrophobic |
NAX | ZN | ZN- 1001 | 2.08 | 0 | Metal Acceptor |
DuAr | ZN | ZN- 1001 | 3.17 | 94.76 | Pi/Cation |