sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 1.000 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.703 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.634 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.630 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.611 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.610 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.610 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.599 | |
| 2on6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.581 | |
| 1a9p | 9DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.575 | |
| 2oc4 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.572 | |
| 1fxu | GU7 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.567 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.558 | |
| 1yry | MSG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.553 | |
| 1b8n | IMG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.546 | |
| 1rct | NOS | Purine nucleoside phosphorylase | 2.4.2.1 | 0.537 | |
| 1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.535 | |
| 3k8o | 229 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.530 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.528 | |
| 1a9s | NOS | Purine nucleoside phosphorylase | 2.4.2.1 | 0.522 | |
| 1b8o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.521 | |
| 3f8w | ADN | Purine nucleoside phosphorylase | / | 0.518 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.515 | |
| 1pf7 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.513 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.513 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.510 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.509 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.509 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.505 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.505 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.504 | |
| 4jic | FMN | GTN Reductase | / | 0.504 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.500 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.499 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.499 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.496 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.496 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.495 | |
| 1mmk | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.494 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.493 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.493 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.492 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.492 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.492 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.492 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.492 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.491 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.490 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.490 | |
| 2p4s | DIH | AGAP005945-PA | / | 0.490 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.490 | |
| 2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.490 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.490 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.489 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.489 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.489 | |
| 1v2h | GUN | Purine nucleoside phosphorylase | 2.4.2.1 | 0.489 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.489 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.489 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.489 | |
| 4ear | IM5 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.489 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.488 | |
| 2ejz | SAH | Diphthine synthase | / | 0.488 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.488 | |
| 5dp2 | NAP | CurF | / | 0.488 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.487 | |
| 4j7h | TRH | PCZA361.3 | / | 0.487 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.486 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.485 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.485 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.484 | |
| 4e2b | FMN | Dehydrogenase | / | 0.484 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.484 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.483 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.483 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.483 | |
| 1y9d | TPP | Pyruvate oxidase | 1.2.3.3 | 0.482 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.482 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.482 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.482 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.482 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.482 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.482 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.482 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.481 | |
| 1v48 | HA1 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.481 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.481 | |
| 3uko | NAD | Alcohol dehydrogenase class-3 | / | 0.481 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.480 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.480 | |
| 3ebl | GA4 | Gibberellin receptor GID1 | / | 0.480 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.480 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.480 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.480 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.480 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.479 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.479 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.479 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.478 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.478 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.478 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.478 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.477 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.477 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.477 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.477 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.477 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.477 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 2o8j | SAH | Histone-lysine N-methyltransferase EHMT2 | / | 0.476 | |
| 2xnv | VU3 | Soluble acetylcholine receptor | / | 0.476 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.476 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.476 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.476 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.476 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.475 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.475 | |
| 1ni1 | 2C5 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.475 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.475 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.475 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.475 | |
| 4knz | CB3 | Thymidylate synthase | / | 0.475 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.474 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.474 | |
| 1ni1 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.473 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.473 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.473 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.473 | |
| 3w2f | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.473 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.473 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.473 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.473 | |
| 5jhn | SAM | Histone-lysine N-methyltransferase EHMT2 | / | 0.473 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.472 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.472 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.472 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.472 | |
| 4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.472 | |
| 1r6t | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.471 | |
| 2v8p | CDP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.471 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.471 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.471 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.471 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.471 | |
| 3qls | 55V | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 4c49 | HCY | Corticosteroid-binding globulin | / | 0.471 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.471 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.471 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.471 | |
| 5czy | SAM | Eukaryotic huntingtin interacting protein B | / | 0.471 | |
| 3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.471 | |
| 1l7x | 700 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.470 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.470 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.470 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.470 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.470 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.470 | |
| 3h59 | H59 | Genome polyprotein | 2.7.7.48 | 0.470 | |
| 3ihg | VAK | Aklavinone 12-hydroxylase RdmE | / | 0.470 | |
| 3wid | NAP | Glucose 1-dehydrogenase | / | 0.470 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.470 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.470 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.469 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.469 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.469 | |
| 1lvu | 9PP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.469 | |
| 1oj4 | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.469 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.469 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.469 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.469 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.469 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.469 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.469 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.469 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.469 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.469 | |
| 4e2d | FMN | Dehydrogenase | / | 0.469 | |
| 4y1b | NAP | AntE | / | 0.469 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.469 | |
| 1h62 | ANB | Pentaerythritol tetranitrate reductase | / | 0.468 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.468 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.468 | |
| 4h6p | FMN | Chromate reductase | / | 0.468 | |
| 5a01 | 12V | O-glycosyltransferase | / | 0.468 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.467 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.467 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.467 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.467 | |
| 4e32 | DWN | Methyltransferase | / | 0.467 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.466 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.466 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.466 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.466 | |
| 2pch | SAH | Diphthine synthase | / | 0.466 | |
| 3af3 | GCP | Pantothenate kinase | 2.7.1.33 | 0.466 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.466 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.466 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.466 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.466 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.466 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.466 | |
| 4du6 | GTP | GTP cyclohydrolase 1 | / | 0.466 | |
| 4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.466 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.465 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 1fml | RTL | Retinol dehydratase | / | 0.465 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.465 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.465 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.465 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.465 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.465 | |
| 2hux | SAH | Diphthine synthase | / | 0.465 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.465 | |
| 3koy | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.465 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.465 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.465 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.465 | |
| 4j49 | 1J1 | Uncharacterized protein | / | 0.465 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.465 | |
| 1a9c | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.464 | |
| 1cbq | RE9 | Cellular retinoic acid-binding protein 2 | / | 0.464 | |
| 1nl4 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.464 | |
| 1owe | 675 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.464 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.464 | |
| 2dvo | ITT | dITP/XTP pyrophosphatase | 3.6.1.19 | 0.464 | |
| 2o4c | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.464 | |
| 3hii | PNT | Amiloride-sensitive amine oxidase [copper-containing] | / | 0.464 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.464 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.464 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.464 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.464 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.463 | |
| 1m9a | GTX | Glutathione S-transferase class-mu 26 kDa isozyme | 2.5.1.18 | 0.463 | |
| 1nuq | NXX | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.463 | |
| 1xds | DRA | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.463 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.463 | |
| 2ek7 | SAH | Diphthine synthase | / | 0.463 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.463 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.463 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.463 | |
| 3b9l | AZZ | Serum albumin | / | 0.463 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.463 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.463 | |
| 3ndj | JHZ | Methyltransferase | / | 0.463 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.463 | |
| 3udn | 09B | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 3vg1 | 0GT | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.463 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.463 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.463 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.462 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.462 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.462 | |
| 1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.462 | |
| 1tys | DHF | Thymidylate synthase | / | 0.462 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.462 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.462 | |
| 3hdy | GDU | UDP-galactopyranose mutase | / | 0.462 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.462 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.462 | |
| 3tg4 | SAM | N-lysine methyltransferase SMYD2 | / | 0.462 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.462 | |
| 4dxl | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.462 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 4x5f | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 4xr9 | NAD | CalS8 | / | 0.462 | |
| 1lv8 | 9PP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.461 | |
| 1nah | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.461 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.461 | |
| 1u71 | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.461 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.461 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.461 | |
| 3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.461 | |
| 4f3x | NAD | Putative aldehyde dehydrogenase | / | 0.461 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.461 | |
| 1cdo | NAD | Alcohol dehydrogenase 1 | 1.1.1.1 | 0.460 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.460 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.460 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.460 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.460 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.460 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 2x90 | EAL | Angiotensin-converting enzyme | 3.4.15.1 | 0.460 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.460 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.460 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.460 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.460 | |
| 4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.460 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.459 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.459 | |
| 1kfc | IPL | Tryptophan synthase alpha chain | / | 0.459 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.459 | |
| 1sdw | IYT | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.459 | |
| 2fr1 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.459 | |
| 2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.459 | |
| 2xaa | NAD | Secondary alcohol dehydrogenase | / | 0.459 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.459 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.459 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.459 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.459 | |
| 3t94 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.459 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.459 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.459 | |
| 1ikg | REX | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.458 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.458 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.458 | |
| 2bkt | RPF | Renin | 3.4.23.15 | 0.458 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.458 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.458 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.458 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.458 | |
| 2zsi | GA4 | Gibberellin receptor GID1A | 3 | 0.458 | |
| 3bgx | TMP | Thymidylate synthase | / | 0.458 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.458 | |
| 3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.458 | |
| 4f7i | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.458 | |
| 4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.457 | |
| 1q23 | FUA | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.457 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.457 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.457 | |
| 1umk | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.457 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.457 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 0.457 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.457 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3jzi | JZL | Biotin carboxylase | 6.3.4.14 | 0.457 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.457 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.457 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 4acx | S8Z | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.457 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.457 | |
| 4dd8 | BAT | Disintegrin and metalloproteinase domain-containing protein 8 | 3.4.24 | 0.457 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.457 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.457 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.457 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.457 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.456 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.456 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1n2h | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.456 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
| 2ii6 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.456 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.456 | |
| 2qn3 | F55 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.456 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 3bw4 | FMN | Putative 2-nitropropane dioxygenase | / | 0.456 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.456 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.456 | |
| 3zhu | TD8 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.456 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.456 | |
| 4dri | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.456 | |
| 4dri | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.456 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.456 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.456 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.456 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.456 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.455 | |
| 1zxn | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.455 | |
| 2gs9 | SAH | Uncharacterized protein | / | 0.455 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.455 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.455 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.455 | |
| 2r0c | FAD | Putative FAD-monooxygenase | / | 0.455 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.455 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.455 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.455 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.455 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.455 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.455 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.455 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.454 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.454 | |
| 1vza | UMP | Thymidylate synthase | / | 0.454 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.454 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.454 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.454 | |
| 3clx | X22 | E3 ubiquitin-protein ligase XIAP | 6.3.2 | 0.454 | |
| 3faz | NOS | Purine nucleoside phosphorylase | / | 0.454 | |
| 3g72 | A6T | Renin | 3.4.23.15 | 0.454 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.454 | |
| 3iex | GMP | Purine nucleoside phosphorylase | / | 0.454 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3u8l | 09Q | Acetylcholine-binding protein | / | 0.454 | |
| 3udj | 092 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.454 | |
| 4a3u | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.454 | |
| 4b67 | NAP | L-ornithine N(5)-monooxygenase | / | 0.454 | |
| 4drh | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.454 | |
| 4drh | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.454 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.454 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1o1s | 1NH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.453 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.453 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.453 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.453 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.453 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.453 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.453 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.453 | |
| 2x93 | X93 | Angiotensin-converting enzyme | 3.4.15.1 | 0.453 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.453 | |
| 3lnc | 5GP | Guanylate kinase | / | 0.453 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.453 | |
| 4die | C5P | Cytidylate kinase | / | 0.453 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.453 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 4lxk | 1YT | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4n82 | FMN | Ribonucleotide reductase (NrdI family protein), putative | / | 0.453 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.453 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.453 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.452 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1eii | RTL | Retinol-binding protein 2 | / | 0.452 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.452 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.452 | |
| 1wkl | ATP | Nucleoside diphosphate kinase | / | 0.452 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.452 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.452 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.452 | |
| 2g0b | NLT | Long-chain N-acyl amino acid synthase | / | 0.452 | |
| 2v2q | NVG | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.452 | |
| 2vqb | FAD | Putative flavin-containing monooxygenase | / | 0.452 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.452 | |
| 3b9x | NOS | Pyrimidine-specific ribonucleoside hydrolase RihB | 3.2.2.8 | 0.452 | |
| 3e32 | ED2 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.452 | |
| 3ens | ENS | Coagulation factor X | 3.4.21.6 | 0.452 | |
| 3fnl | SHA | Lactoperoxidase | / | 0.452 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.452 | |
| 3gki | CLR | Niemann-Pick C1 protein | / | 0.452 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.452 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.452 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.452 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.452 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.452 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.452 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.452 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.452 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.452 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.452 | |
| 4n3r | 2GU | Tankyrase-1 | 2.4.2.30 | 0.452 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.452 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.452 | |
| 4r1f | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.452 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.452 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.452 | |
| 5a3c | NAD | SIR2 family protein | / | 0.452 | |
| 5bnw | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.452 | |
| 4s0v | SUV | Orexin receptor type 2 | / | 0.452 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.451 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.451 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 2fxu | BID | Actin, alpha skeletal muscle | / | 0.451 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.451 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 2h2a | DND | Probable nicotinate-nucleotide adenylyltransferase | / | 0.451 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.451 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.451 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 2viy | VG3 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 2w4q | CBW | Prostaglandin reductase 2 | 1.3.1.48 | 0.451 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 2zrx | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.451 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.451 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.451 | |
| 3hdq | GDU | UDP-galactopyranose mutase | / | 0.451 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.451 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.451 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.451 | |
| 3zia | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.451 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.451 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.451 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.451 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4kc2 | WS2 | Histo-blood group ABO system transferase | / | 0.451 | |
| 4y0k | NAP | AntE | / | 0.451 | |
| 4mqt | 2CU | Muscarinic acetylcholine receptor M2 | / | 0.451 | |
| 1cbr | REA | Cellular retinoic acid-binding protein 1 | / | 0.450 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 1k7f | IAV | Tryptophan synthase alpha chain | / | 0.450 | |
| 1n4q | LYS_CYS_VAL_ILE_LEU | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.450 | |
| 1til | ATP | Anti-sigma F factor | / | 0.450 | |
| 1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.450 | |
| 1wwz | ACO | Uncharacterized protein | / | 0.450 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.450 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.450 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.450 | |
| 2aa3 | AP0 | L-lactate dehydrogenase | / | 0.450 | |
| 2djx | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.450 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.450 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.450 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.450 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.450 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.450 | |
| 2wwj | Y28 | Lysine-specific demethylase 4A | / | 0.450 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.450 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 3fpd | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.450 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.450 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.450 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.450 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3qbj | NXZ | Dipeptidyl peptidase 4 | / | 0.450 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.450 | |
| 3up0 | D7S | aceDAF-12 | / | 0.450 | |
| 3vwd | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.450 | |
| 3vye | VYE | Renin | 3.4.23.15 | 0.450 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 4e2y | JHZ | Methyltransferase | / | 0.450 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.450 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.450 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.450 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.450 | |
| 4u9v | ACO | N-alpha-acetyltransferase 40 | 2.3.1 | 0.450 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.450 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.450 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.450 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1i0s | FMN | Ferric-chelate reductase (NAD(P)H) | / | 0.449 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.449 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.449 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.449 | |
| 1v45 | 3DG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.449 | |
| 2dsg | SAH | Diphthine synthase | / | 0.449 | |
| 2e4n | SAH | Diphthine synthase | / | 0.449 | |
| 2iib | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.449 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.449 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 2xvq | 9DS | Serum albumin | / | 0.449 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.449 | |
| 3cgb | COA | Coenzyme A disulfide reductase | / | 0.449 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.449 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.449 | |
| 3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.449 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.449 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.449 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.449 | |
| 4fm8 | 0UQ | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4irn | FAD | AnaB | / | 0.449 | |
| 4l5a | TBN | S-methyl-5'-thioadenosine phosphorylase | / | 0.449 | |
| 4oqy | NDP | (S)-imine reductase | / | 0.449 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.449 | |
| 5cfl | C2E | Stimulator of interferon genes protein | / | 0.449 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.448 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.448 | |
| 1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.448 | |
| 1kw0 | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.448 | |
| 1pvg | ANP | DNA topoisomerase 2 | 5.99.1.3 | 0.448 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.448 | |
| 1xdu | SFG | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.448 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.448 | |
| 2bla | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.448 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.448 | |
| 2fs4 | PZ1 | Renin | 3.4.23.15 | 0.448 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.448 | |
| 2v5a | LZL | Biotin carboxylase | 6.3.4.14 | 0.448 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.448 | |
| 2wnb | C5P | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 | 2.4.99.4 | 0.448 | |
| 2zwa | SAH | tRNA wybutosine-synthesizing protein 4 | 2.1.1.290 | 0.448 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.448 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.448 | |
| 3c36 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.448 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3fpa | DTB | ATP-dependent dethiobiotin synthetase BioD | / | 0.448 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.448 | |
| 3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.448 | |
| 3u9e | COA | Lmo1369 protein | / | 0.448 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.448 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 4dk7 | 0KS | Oxysterols receptor LXR-beta | / | 0.448 | |
| 4eqs | COA | Coenzyme A disulfide reductase | / | 0.448 | |
| 4h1q | 0XX | Matrix metalloproteinase-9 | 3.4.24.35 | 0.448 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.448 | |
| 4loi | 1YC | Stimulator of interferon genes protein | / | 0.448 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.448 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.448 | |
| 4to5 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.448 | |
| 5jin | SAM | Histone-lysine N-methyltransferase EHMT2 | / | 0.448 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1e2n | RCA | Thymidine kinase | / | 0.447 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.447 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.447 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.447 | |
| 1uu9 | BI3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
| 1v5z | 2HC | Major NAD(P)H-flavin oxidoreductase | 1.6.99 | 0.447 | |
| 1w76 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.447 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.447 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.447 | |
| 2qen | ADP | Walker-Type ATPase | / | 0.447 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.447 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.447 | |
| 3f0a | ACO | Spermidine N(1)-acetyltransferase | / | 0.447 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.447 | |
| 3lpg | Z78 | Beta-glucuronidase | 3.2.1.31 | 0.447 | |
| 3mo0 | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.447 | |
| 3n4l | 842 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.447 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.447 | |
| 3r95 | ACO | MccE protein | / | 0.447 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.447 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.447 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.447 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.447 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.447 | |
| 4dja | FAD | (6-4) photolyase | / | 0.447 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.447 | |
| 4h6k | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.447 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.447 | |
| 1bzf | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1ezv | UQ6 | Cytochrome b | / | 0.446 | |
| 1tys | TMP | Thymidylate synthase | / | 0.446 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.446 | |
| 1xzq | FON | tRNA modification GTPase MnmE | 3.6.5 | 0.446 | |
| 2anb | 5GP | Guanylate kinase | 2.7.4.8 | 0.446 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.446 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.446 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.446 | |
| 2ou5 | FMN | Pyridoxamine 5'-phosphate oxidase-related FMN-binding protein | / | 0.446 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.446 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.446 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.446 | |
| 3beo | UD1 | UDP-N-acetylglucosamine 2-epimerase | / | 0.446 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.446 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.446 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.446 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.446 | |
| 3pd2 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.446 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.446 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.446 | |
| 3wyc | NAP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.446 | |
| 4ba5 | PXG | Probable aminotransferase | / | 0.446 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.446 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.446 | |
| 4i0h | 1BL | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.446 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.446 | |
| 4ubv | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.446 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.446 | |
| 5ftf | ADP | TPR domain protein | / | 0.446 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.445 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.445 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.445 | |
| 1tdu | DUR | Thymidylate synthase | / | 0.445 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.445 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.445 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.445 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2ohv | NHL | Glutamate racemase | / | 0.445 | |
| 2v1a | FMN | NPH1-1 | / | 0.445 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.445 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.445 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.445 | |
| 3gb4 | D3M | DdmC | / | 0.445 | |
| 3haz | FAD | Bifunctional protein PutA | / | 0.445 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.445 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.445 | |
| 3zcn | ATP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.445 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.445 | |
| 4avl | TMP | Polymerase acidic protein | / | 0.445 | |
| 4b3a | TAC | Tetracycline repressor protein class D | / | 0.445 | |
| 4blc | NDP | Catalase | 1.11.1.6 | 0.445 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.445 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.445 | |
| 4la7 | A1O | Abscisic acid receptor PYL2 | / | 0.445 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.445 | |
| 4rel | KMP | Glycosyltransferase | / | 0.445 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.445 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.445 | |
| 1f4g | TP4 | Thymidylate synthase | / | 0.444 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.444 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.444 | |
| 1wxj | IPL | Tryptophan synthase alpha chain | / | 0.444 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 2a7r | 5GP | GMP reductase 2 | / | 0.444 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.444 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.444 | |
| 2hpv | FMN | FMN-dependent NADH-azoreductase | 1.7 | 0.444 | |
| 2i3g | NAP | N-acetyl-gamma-glutamyl-phosphate reductase | 1.2.1.38 | 0.444 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.444 | |
| 2xys | SY9 | Soluble acetylcholine receptor | / | 0.444 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.444 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.444 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.444 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.444 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.444 | |
| 3ksq | Z96 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.444 | |
| 3p80 | P80 | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 3wag | TYD | Glycosyltransferase | / | 0.444 | |
| 4c3y | FAD | 3-ketosteroid dehydrogenase | / | 0.444 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 4cr8 | NAD | N-acylmannosamine 1-dehydrogenase | 1.1.1.233 | 0.444 | |
| 4n3c | UD1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.444 | |
| 4v0s | 2HN | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.444 | |
| 4v12 | POG | MaoC like domain protein | / | 0.444 | |
| 4y9l | FAD | Acyl-CoA dehydrogenase family member 11 | / | 0.444 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.444 | |
| 4yqf | GDP | Septin-9 | / | 0.444 | |
| 5hq8 | SAH | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.444 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.444 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.443 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.443 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1kr2 | TAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.443 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.443 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.443 | |
| 1upc | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.443 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.443 | |
| 2cwf | NDP | Delta(1)-pyrroline-2-carboxylate/Delta(1)-piperideine-2-carboxylate reductase | / | 0.443 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.443 | |
| 2hl2 | SSA | Threonine--tRNA ligase | 6.1.1.3 | 0.443 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.443 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.443 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.443 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.443 | |
| 2vat | COA | Acetyl-CoA--deacetylcephalosporin C acetyltransferase | 2.3.1.175 | 0.443 | |
| 3c49 | KU8 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.443 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.443 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.443 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.443 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.443 | |
| 3rba | COD | Phosphopantetheine adenylyltransferase | / | 0.443 | |
| 3rvh | HQ2 | Lysine-specific demethylase 4A | 1.14.11 | 0.443 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.443 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4bf9 | FMN | tRNA-dihydrouridine(16) synthase | / | 0.443 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.443 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.443 | |
| 4rr6 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.443 | |
| 4u0m | GTP | Cyclic GMP-AMP synthase | / | 0.443 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.443 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.443 | |
| 4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 4zla | BES | Cytosol aminopeptidase | 3.4.11.1 | 0.443 | |
| 5eio | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.443 | |
| 1b8v | NAD | Malate dehydrogenase | / | 0.442 | |
| 1g28 | FMN | PHY3 | / | 0.442 | |
| 1hdo | NAP | Flavin reductase (NADPH) | / | 0.442 | |
| 1jqi | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | / | 0.442 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.442 | |
| 1p52 | ADP | Arginine kinase | 2.7.3.3 | 0.442 | |
| 1w19 | T1P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.442 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.442 | |
| 2a8y | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.442 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.442 | |
| 2d3a | ADP | Glutamine synthetase root isozyme 3 | 6.3.1.2 | 0.442 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.442 | |
| 2eeq | SAH | Diphthine synthase | / | 0.442 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.442 | |
| 2emu | SAH | Diphthine synthase | / | 0.442 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.442 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.442 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.442 | |
| 2vte | IK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.442 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.442 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.442 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.442 | |
| 3bkk | KAF | Angiotensin-converting enzyme | 3.2.1 | 0.442 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.442 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3h2s | NDP | Putative NADH-flavin reductase | / | 0.442 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.442 | |
| 3nyt | ULP | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.442 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.442 | |
| 3vf3 | 0GS | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3wb2 | YGP | Uncharacterized protein MJ0488 | / | 0.442 | |
| 3x2f | NAI | Adenosylhomocysteinase | / | 0.442 | |
| 3zht | TD9 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.442 | |
| 4b05 | 32D | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.442 | |
| 4b72 | 2FB | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4bv9 | NDP | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.442 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.442 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.442 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.442 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
| 4kxj | P34 | Nucleoprotein | / | 0.442 | |
| 4n1g | CEI | Obelin | / | 0.442 | |
| 4o7u | THF | Thymidylate synthase | / | 0.442 | |
| 4s1i | PLP | Pyridoxal kinase, putative | / | 0.442 | |
| 5a1t | NAI | L-lactate dehydrogenase | / | 0.442 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.442 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.441 | |
| 1dlj | UGA | UDP-glucose 6-dehydrogenase | / | 0.441 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.441 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.441 | |
| 1g6o | ADP | Cag alpha | / | 0.441 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1oyc | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.441 | |
| 1pax | DHQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.441 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.441 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.441 | |
| 1xh7 | R96 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 1y56 | FAD | 382aa long hypothetical sarcosine oxidase | / | 0.441 | |
| 1yre | COA | Uncharacterized protein | / | 0.441 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.441 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.441 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.441 | |
| 2ji6 | TPW | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.441 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.441 | |
| 2rfi | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.441 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.441 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2zrf | DTP | Protein RecA | / | 0.441 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.441 | |
| 3c34 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.441 | |
| 3clu | FAD | Electron transfer flavoprotein subunit alpha | / | 0.441 | |
| 3dme | FAD | Putative conserved exported protein | / | 0.441 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.441 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.441 | |
| 3isj | A8D | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 3ld6 | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.441 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.441 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.441 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.441 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.441 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.441 | |
| 4kw5 | 1W6 | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.441 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.441 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.441 | |
| 1cjv | FOK | Adenylate cyclase type 2 | / | 0.440 | |
| 1cjv | FOK | Adenylate cyclase type 5 | / | 0.440 | |
| 1ddu | DDU | Thymidylate synthase | / | 0.440 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.440 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.440 | |
| 1ld8 | U49 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 1n3s | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.440 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.440 | |
| 1tsx | UMP | Thymidylate synthase | / | 0.440 | |
| 2b8j | ADN | Class B acid phosphatase | 3.1.3.2 | 0.440 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.440 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.440 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.440 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.440 | |
| 2qmy | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.440 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.440 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.440 | |
| 2xfy | ACX | Beta-amylase | 3.2.1.2 | 0.440 | |
| 3co9 | 3MS | Genome polyprotein | 2.7.7.48 | 0.440 | |
| 3f6s | FMN | Flavodoxin | / | 0.440 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.440 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.440 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.440 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.440 | |
| 3jv7 | NAD | Secondary alcohol dehydrogenase | / | 0.440 | |
| 3kjg | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.440 | |
| 3mkn | DNB | Pyrimidine-specific ribonucleoside hydrolase RihB | / | 0.440 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.440 | |
| 3veu | 0GO | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 | |
| 4m5p | FMN | NADPH dehydrogenase | / | 0.440 | |
| 4qof | FMN | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.440 |