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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4ek9 EP4 Histone-lysine N-methyltransferase, H3 lysine-79 specific 2.1.1.43

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4ek9 EP4Histone-lysine N-methyltransferase, H3 lysine-79 specific 2.1.1.43 0.747
13gs SASGlutathione S-transferase P 2.5.1.18 0.744
1a27 ESTEstradiol 17-beta-dehydrogenase 1 1.1.1.62 0.744
1agw SU2Fibroblast growth factor receptor 1 / 0.744
1b8y IN7Stromelysin-1 3.4.24.17 0.744
1c23 MPHMethionine aminopeptidase / 0.744
1cqp 803Integrin alpha-L / 0.744
1d7o TCLEnoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic 1.3.1.9 0.744
1dcy I3NPhospholipase A2, membrane associated / 0.744
1dia L24C-1-tetrahydrofolate synthase, cytoplasmic 1.5.1.5 0.744
1dpm EBPParathion hydrolase 3.1.8.1 0.744
1dz4 CAMCamphor 5-monooxygenase 1.14.15.1 0.744
1dz8 CAMCamphor 5-monooxygenase 1.14.15.1 0.744
1e2j THMThymidine kinase / 0.744
1e6v COMMethyl-coenzyme M reductase I subunit alpha / 0.744
1e6v COMMethyl coenzyme M reductase, beta subunit / 0.744
1e7v LY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 2.7.1.153 0.744
1e8z STUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 2.7.1.153 0.744
1eii RTLRetinol-binding protein 2 / 0.744
1eko I84Aldose reductase 1.1.1.21 0.744
1eqa MG7Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2.1.1.57 0.744
1equ EQIEstradiol 17-beta-dehydrogenase 1 1.1.1.62 0.744
1eup ASD6-deoxyerythronolide B hydroxylase / 0.744
1ezv UQ6Cytochrome b / 0.744
1fcy 564Retinoic acid receptor gamma / 0.744
1fdw ESTEstradiol 17-beta-dehydrogenase 1 1.1.1.62 0.744
1fls WAYCollagenase 3 3.4.24 0.744
1fm1 WAYCollagenase 3 3.4.24 0.744
1fx9 MJIPhospholipase A2, major isoenzyme 3.1.1.4 0.744
1fxf MJIPhospholipase A2, major isoenzyme 3.1.1.4 0.744
1fxv PNNPenicillin G acylase 3.5.1.11 0.744
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
1geb CAMCamphor 5-monooxygenase 1.14.15.1 0.744
1gm8 SOXPenicillin G acylase 3.5.1.11 0.744
1gs3 EQUSteroid Delta-isomerase 5.3.3.1 0.744
1gsf EAAGlutathione S-transferase A1 2.5.1.18 0.744
1gt5 BZQOdorant-binding protein / 0.744
1h66 RH1NAD(P)H dehydrogenase [quinone] 1 1.6.5.2 0.744
1h9z RWFSerum albumin / 0.744
1hdc CBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase 1.1.1.53 0.744
1hpz AAPGag-Pol polyprotein 2.7.7.49 0.744
1i00 D16Thymidylate synthase 2.1.1.45 0.744
1iiu RTLRetinol-binding protein 4 / 0.744
1iqh XMFCoagulation factor X 3.4.21.6 0.744
1iwi CAMCamphor 5-monooxygenase 1.14.15.1 0.744
1iwj CAMCamphor 5-monooxygenase 1.14.15.1 0.744
1j91 TBSCasein kinase II subunit alpha 2.7.11.1 0.744
1jg0 DDTThymidylate synthase / 0.744
1kt4 RTLRetinol-binding protein 4 / 0.744
1kt5 RTLRetinol-binding protein 4 / 0.744
1kt6 RTLRetinol-binding protein 4 / 0.744
1kt7 RTLRetinol-binding protein 4 / 0.744
1kw9 BPYBiphenyl-2,3-diol 1,2-dioxygenase 1.13.11.39 0.744
1kwc BPYBiphenyl-2,3-diol 1,2-dioxygenase 1.13.11.39 0.744
1kyz FERCaffeic acid 3-O-methyltransferase 2.1.1.68 0.744
1l0l FMXCytochrome b / 0.744
1ld7 U66Protein farnesyltransferase subunit beta 2.5.1.58 0.744
1ld8 U49Protein farnesyltransferase subunit beta 2.5.1.58 0.744
1lnm DTXBilin-binding protein / 0.744
1lri CLRBeta-elicitin cryptogein / 0.744
1m17 AQ4Epidermal growth factor receptor 2.7.10.1 0.744
1m67 BOAGlycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal 1.1.1.8 0.744
1mdl RMNMandelate racemase / 0.744
1mr9 ACOStreptogramin A acetyltransferase 2.3.1 0.744
1mzc BNEProtein farnesyltransferase subunit beta 2.5.1.58 0.744
1n5q TNCActVA 6 protein / 0.744
1n95 FTHProtein farnesyltransferase subunit beta 2.5.1.58 0.744
1ni1 2C5Protein farnesyltransferase subunit beta 2.5.1.58 0.744
1noo CAHCamphor 5-monooxygenase 1.14.15.1 0.744
1nvs UCMSerine/threonine-protein kinase Chk1 2.7.11.1 0.744
1o1v TCHGastrotropin / 0.744
1o76 CAMCamphor 5-monooxygenase 1.14.15.1 0.744
1ogx EQUSteroid Delta-isomerase 5.3.3.1 0.744
1oho EQUSteroid Delta-isomerase 5.3.3.1 0.744
1phg MYTCamphor 5-monooxygenase 1.14.15.1 0.744
1pmn 984Mitogen-activated protein kinase 10 2.7.11.24 0.744
1pp9 SMACytochrome b / 0.744
1pr1 FMBPurine nucleoside phosphorylase DeoD-type / 0.744
1pxk CK3Cyclin-dependent kinase 2 2.7.11.22 0.744
1pye PM1Cyclin-dependent kinase 2 2.7.11.22 0.744
1q13 TESProstaglandin-E(2) 9-reductase 1.1.1.189 0.744
1q8u H52cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.744
1qy2 IPZMajor urinary protein 1 / 0.744
1qyw 5SDEstradiol 17-beta-dehydrogenase 1 1.1.1.62 0.744
1qyx ASDEstradiol 17-beta-dehydrogenase 1 1.1.1.62 0.744
1rd4 L08Integrin alpha-L / 0.744
1re9 DSOCamphor 5-monooxygenase 1.14.15.1 0.744
1rf9 DBRCamphor 5-monooxygenase 1.14.15.1 0.744
1rw8 580TGF-beta receptor type-1 2.7.11.30 0.744
1sa5 BMVProtein farnesyltransferase subunit beta 2.5.1.58 0.744
1sjw NGVNogalonic acid methyl ester cyclase / 0.744
1sn0 T44Transthyretin / 0.744
1sqi 8694-hydroxyphenylpyruvate dioxygenase / 0.744
1sqn NDRProgesterone receptor / 0.744
1sqq OSTCytochrome b / 0.744
1sqv UHDCytochrome b / 0.744
1t48 BB3Tyrosine-protein phosphatase non-receptor type 1 3.1.3.48 0.744
1t4e DIZE3 ubiquitin-protein ligase Mdm2 6.3.2 0.744
1t85 CAMCamphor 5-monooxygenase 1.14.15.1 0.744
1t86 CAMCamphor 5-monooxygenase 1.14.15.1 0.744
1t87 CAMCamphor 5-monooxygenase 1.14.15.1 0.744
1t88 CAMCamphor 5-monooxygenase 1.14.15.1 0.744
1tbb ROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D 3.1.4.53 0.744
1tsl A15Thymidylate synthase / 0.744
1ttm 667Carbonic anhydrase 2 4.2.1.1 0.744
1u1j C2F5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 1 2.1.1.14 0.744
1u3w FXYAlcohol dehydrogenase 1C 1.1.1.1 0.744
1uk0 FRMPoly [ADP-ribose] polymerase 1 2.4.2.30 0.744
1upj U01Gag-Pol polyprotein / 0.744
1vkg CRIHistone deacetylase 8 3.5.1.98 0.744
1wma AB3Carbonyl reductase [NADPH] 1 1.1.1.184 0.744
1wpg ADPSarcoplasmic/endoplasmic reticulum calcium ATPase 1 3.6.3.8 0.744
1wuw TSUBeta-hordothionin / 0.744
1x2h LPALipoate-protein ligase A 6.3.1.20 0.744
1xdd AAYIntegrin alpha-L / 0.744
1xds DRAAclacinomycin 10-hydroxylase RdmB 4.1.1 0.744
1xf0 ASDAldo-keto reductase family 1 member C3 / 0.744
1xkk FMMEpidermal growth factor receptor 2.7.10.1 0.744
1xnz FCDMethionine aminopeptidase / 0.744
1y2b DEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D 3.1.4.53 0.744
1y2d 4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D 3.1.4.53 0.744
1y2k 7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D 3.1.4.53 0.744
1ya8 MVBLiver carboxylesterase 1 / 0.744
1ydr IQPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.744
1yrc CAMCamphor 5-monooxygenase 1.14.15.1 0.744
1yrd CAMCamphor 5-monooxygenase 1.14.15.1 0.744
1ysx 4EBSerum albumin / 0.744
1yw7 A41Methionine aminopeptidase 2 / 0.744
1zkn IBMcAMP-specific 3',5'-cyclic phosphodiesterase 4D 3.1.4.53 0.744
1zsn TN2Enoyl-ACP reductase / 0.744
1zx1 CB1Ribosyldihydronicotinamide dehydrogenase [quinone] / 0.744
2a1n CAMCamphor 5-monooxygenase 1.14.15.1 0.744
2a1o CAMCamphor 5-monooxygenase 1.14.15.1 0.744
2a3b CFFEndochitinase B1 3.2.1.14 0.744
2a5u QYTPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 2.7.1.153 0.744
2ab2 SNLMineralocorticoid receptor / 0.744
2agv TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 3.6.3.8 0.744
2aib ERGBeta-elicitin cinnamomin / 0.744
2aou CQAHistamine N-methyltransferase 2.1.1.8 0.744
2aq7 TL53-oxoacyl-[acyl-carrier-protein] synthase 1 2.3.1.41 0.744
2b35 TCLEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.744
2brb PFQSerine/threonine-protein kinase Chk1 2.7.11.1 0.744
2brg DFYSerine/threonine-protein kinase Chk1 2.7.11.1 0.744
2bu7 TF3[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial 2.7.11.2 0.744
2bx8 AZQSerum albumin / 0.744
2bxe 1FLSerum albumin / 0.744
2bxf DZPSerum albumin / 0.744
2bxi AZQSerum albumin / 0.744
2bxm IMNSerum albumin / 0.744
2bxq IMNSerum albumin / 0.744
2c3i IYZSerine/threonine-protein kinase pim-1 2.7.11.1 0.744
2cbo TH2Neocarzinostatin / 0.744
2cbq TH2Neocarzinostatin / 0.744
2chw 039Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 2.7.1.153 0.744
2chx 090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 2.7.1.153 0.744
2cji GSKCoagulation factor X 3.4.21.6 0.744
2cke IQUDeath-associated protein kinase 2 / 0.744
2cpp CAMCamphor 5-monooxygenase 1.14.15.1 0.744
2csn CKICasein kinase I homolog 1 2.7.11.1 0.744
2d06 ESTSulfotransferase 1A1 2.8.2.1 0.744
2d2g DZZPhosphotriesterase / 0.744
2dqs TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 3.6.3.8 0.744
2ea2 F77Methionine aminopeptidase 2 / 0.744
2eg2 ATPNitrogen regulatory protein P-II / 0.744
2etm 7PYFocal adhesion kinase 1 2.7.10.2 0.744
2f2u M77Rho-associated protein kinase 2 2.7.11.1 0.744
2f98 NGVAklanonic acid methyl ester cyclase AcmA 5.5.1.23 0.744
2fdu D1GCytochrome P450 2A6 1.14.13 0.744
2fdv D2GCytochrome P450 2A6 1.14.13 0.744
2fdy D4GCytochrome P450 2A6 1.14.13 0.744
2feu CAMCamphor 5-monooxygenase 1.14.15.1 0.744
2fvc 888Polyprotein / 0.744
2fyu FDNCytochrome b / 0.744
2g0l FLNNeocarzinostatin / 0.744
2g97 DGBNicotinamide phosphoribosyltransferase 2.4.2.12 0.744
2ga2 A19Methionine aminopeptidase 2 / 0.744
2gh6 CF3Histone deacetylase-like amidohydrolase 3.5.1 0.744
2giq NN2Genome polyprotein 2.7.7.48 0.744
2gnl H52cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.744
2gz7 D3FOrf1a polyprotein / 0.744
2h6i CYS_VAL_LEU_SER_GERProtein farnesyltransferase subunit beta 2.5.1.58 0.744
2h8h H8HProto-oncogene tyrosine-protein kinase Src 2.7.10.2 0.744
2h96 893Mitogen-activated protein kinase 8 2.7.11.24 0.744
2hrc CHDFerrochelatase, mitochondrial 4.99.1.1 0.744
2i4j DRJPeroxisome proliferator-activated receptor gamma / 0.744
2ij7 TPFMycocyclosin synthase 1.14.21.9 0.744
2ilt NN1Corticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.744
2itu ITQEpidermal growth factor receptor 2.7.10.1 0.744
2itw ITQEpidermal growth factor receptor 2.7.10.1 0.744
2ivu ZD6Proto-oncogene tyrosine-protein kinase receptor Ret 2.7.10.1 0.744
2j0d ERYCytochrome P450 3A4 / 0.744
2j34 GS6Coagulation factor X 3.4.21.6 0.744
2j3j HC4NADPH-dependent oxidoreductase 2-alkenal reductase 1.3.1.74 0.744
2j3q TFLAcetylcholinesterase 3.1.1.7 0.744
2j5s KTAAlr4455 protein / 0.744
2jiz STLATP synthase subunit alpha, mitochondrial / 0.744
2jiz STLATP synthase subunit gamma, mitochondrial / 0.744
2jn3 JN3Fatty acid-binding protein, liver / 0.744
2l98 STLTroponin C, slow skeletal and cardiac muscles / 0.744
2lbv EB4Extracellular fatty acid-binding protein / 0.744
2m56 CAMCamphor 5-monooxygenase 1.14.15.1 0.744
2mji KTRFatty acid-binding protein, intestinal / 0.744
2o0u C0MMitogen-activated protein kinase 10 2.7.11.24 0.744
2o2s TCLEnoyl-acyl carrier reductase / 0.744
2o2u 738Mitogen-activated protein kinase 10 2.7.11.24 0.744
2o2y TCLEnoyl-ACP reductase / 0.744
2o3z AI7UDP-3-O-acyl-N-acetylglucosamine deacetylase / 0.744
2oax SNLMineralocorticoid receptor / 0.744
2oaz I96Methionine aminopeptidase 2 / 0.744
2of2 547Tyrosine-protein kinase Lck 2.7.10.2 0.744
2oli IOPBasic phospholipase A2 VRV-PL-VIIIa 3.1.1.4 0.744
2om9 AJAPeroxisome proliferator-activated receptor gamma / 0.744
2op1 8PCEnoyl-ACP reductase / 0.744
2p4y C03Peroxisome proliferator-activated receptor gamma / 0.744
2pnj CHDFerrochelatase, mitochondrial 4.99.1.1 0.744
2po7 CHDFerrochelatase, mitochondrial 4.99.1.1 0.744
2pws IBPBasic phospholipase A2 VRV-PL-VIIIa 3.1.1.4 0.744
2q7g CCLPyrrolysine--tRNA ligase / 0.744
2q85 973UDP-N-acetylenolpyruvoylglucosamine reductase 1.3.1.98 0.744
2qbo CAMCamphor 5-monooxygenase 1.14.15.1 0.744
2qd4 CHDFerrochelatase, mitochondrial 4.99.1.1 0.744
2qvy 34Z4-chlorobenzoyl CoA ligase / 0.744
2qvz 3BZ4-chlorobenzoyl CoA ligase / 0.744
2qw0 34Z4-chlorobenzoyl CoA ligase / 0.744
2r2g EMFEugenol synthase 1 1.1.1.318 0.744
2r2l PB9Protein farnesyltransferase subunit beta 2.5.1.58 0.744
2rki TT1Gag-Pol polyprotein 2.7.7.49 0.744
2rqf JH3Hemolymph juvenile hormone binding protein / 0.744
2rr1 W8RGenome polyprotein / 0.744
2rs1 W84Genome polyprotein / 0.744
2uxu NARHTH-type transcriptional regulator TtgR / 0.744
2v0m KLNCytochrome P450 3A4 / 0.744
2vcq D25Hematopoietic prostaglandin D synthase / 0.744
2vcw ZZAHematopoietic prostaglandin D synthase / 0.744
2vd0 D27Hematopoietic prostaglandin D synthase / 0.744
2w8y NDRProgesterone receptor / 0.744
2w98 P1ZProstaglandin reductase 2 1.3.1.48 0.744
2x1z PIDPeridinin-chlorophyll a-binding protein 1, chloroplastic / 0.744
2x20 PIDPeridinin-chlorophyll a-binding protein 1, chloroplastic / 0.744
2x21 PIDPeridinin-chlorophyll a-binding protein 1, chloroplastic / 0.744
2x23 TCUEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.744
2x7h PFNProstaglandin reductase 3 1 0.744
2x7u WZACarbonic anhydrase 2 4.2.1.1 0.744
2xf0 4UBSerine/threonine-protein kinase Chk1 2.7.11.1 0.744
2xhx T5MHeat shock protein HSP 90-alpha / 0.744
2xvw 9NRSerum albumin / 0.744
2xx9 1NFGlutamate receptor 2 / 0.744
2y02 Y01Beta-1 adrenergic receptor / 0.744
2y03 Y01Beta-1 adrenergic receptor / 0.744
2y0j AXCcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 3.1.4.17 0.744
2y5h Y5HCoagulation factor X 3.4.21.6 0.744
2y82 930Coagulation factor X 3.4.21.6 0.744
2yxj N3CBcl-2-like protein 1 / 0.744
2zaw CAMCamphor 5-monooxygenase 1.14.15.1 0.744
2zax CAMCamphor 5-monooxygenase 1.14.15.1 0.744
2zb4 5OPProstaglandin reductase 2 1.3.1.48 0.744
2zba ZBATrichothecene 3-O-acetyltransferase / 0.744
2zju IM4Acetylcholine-binding protein / 0.744
2zui CAMCamphor 5-monooxygenase 1.14.15.1 0.744
3acj KSSTyrosine-protein kinase Lck 2.7.10.2 0.744
3am3 TCLEnoyl-ACP reductase / 0.744
3am4 FT1Enoyl-ACP reductase / 0.744
3am5 TCLEnoyl-ACP reductase / 0.744
3aos JH2Hemolymph juvenile hormone binding protein / 0.744
3aox EMHALK tyrosine kinase receptor 2.7.10.1 0.744
3ar7 TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 3.6.3.8 0.744
3arv SAUChitinase A / 0.744
3arz I5IChitinase A / 0.744
3av7 KYAUncharacterized protein / 0.744
3bfb 9ODPheromone-binding protein ASP1 / 0.744
3bhm AB3Carbonyl reductase [NADPH] 1 1.1.1.184 0.744
3bsc 2PDGenome polyprotein 2.7.7.48 0.744
3bto SSBAlcohol dehydrogenase E chain 1.1.1.1 0.744
3cav CI23-oxo-5-beta-steroid 4-dehydrogenase / 0.744
3cmf PDN3-oxo-5-beta-steroid 4-dehydrogenase / 0.744
3cot STR3-oxo-5-beta-steroid 4-dehydrogenase / 0.744
3cpp CAMCamphor 5-monooxygenase 1.14.15.1 0.744
3cwk REACellular retinoic acid-binding protein 2 / 0.744
3cyz 9ODPheromone-binding protein ASP1 / 0.744
3czr 3CZCorticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.744
3d3e D3ECorticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.744
3d77 NBBPheromone-binding protein ASP1 / 0.744
3d90 NOGProgesterone receptor / 0.744
3dei RXBCaspase-3 3.4.22.56 0.744
3dej RXCCaspase-3 3.4.22.56 0.744
3dho B2MStreptogramin A acetyltransferase 2.3.1 0.744
3dle GFAGag-Pol polyprotein 2.7.7.49 0.744
3dpd 41APhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 2.7.1.153 0.744
3dxj NE6DNA-directed RNA polymerase subunit beta / 0.744
3dxj NE6DNA-directed RNA polymerase subunit beta' / 0.744
3dxm N24Actin-related protein 3 / 0.744
3dy7 1CXDual specificity mitogen-activated protein kinase kinase 1 2.7.12.2 0.744
3dyl IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A / 0.744
3dys IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A / 0.744
3e32 ED2Protein farnesyltransferase subunit beta 2.5.1.58 0.744
3egk M18Prothrombin 3.4.21.5 0.744
3etg GWDGlutamate dehydrogenase 1, mitochondrial 1.4.1.3 0.744
3f8c HT1Transcriptional regulator, PadR-like family / 0.744
3fco IIGCorticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.744
3fnu 006HAP protein / 0.744
3for ZNPThermolysin 3.4.24.27 0.744
3fsf FSSMitogen-activated protein kinase 14 / 0.744
3fu9 KIBLaccase-1 1.10.3.2 0.744
3fwf CAMCamphor 5-monooxygenase 1.14.15.1 0.744
3fwg CAMCamphor 5-monooxygenase 1.14.15.1 0.744
3fwi CAMCamphor 5-monooxygenase 1.14.15.1 0.744
3fwj CAMCamphor 5-monooxygenase 1.14.15.1 0.744
3g1r FIT3-oxo-5-beta-steroid 4-dehydrogenase / 0.744
3g58 988cAMP-specific 3',5'-cyclic phosphodiesterase 4D 3.1.4.53 0.744
3gam MXXRibosyldihydronicotinamide dehydrogenase [quinone] / 0.744
3gus N11Glutathione S-transferase P 2.5.1.18 0.744
3h0a 9RARetinoic acid receptor RXR-alpha / 0.744
3h18 PMSEsterase/lipase / 0.744
3h6k 33TCorticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.744
3ha8 5JZMitogen-activated protein kinase 14 / 0.744
3hxb BD5Geranylgeranyl transferase type-2 subunit beta 2.5.1.60 0.744
3hy4 N5G5-formyltetrahydrofolate cyclo-ligase 6.3.3.2 0.744
3hyw DCQSulfide-quinone reductase / 0.744
3iak EV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D 3.1.4.53 0.744
3ii4 3IIDihydrolipoyl dehydrogenase 1.8.1.4 0.744
3iiu PIDPeridinin-chlorophyll a-binding protein 1, chloroplastic / 0.744
3il5 B823-oxoacyl-[acyl-carrier-protein] synthase 3 / 0.744
3img BZ3Pantothenate synthetase 6.3.2.1 0.744
3ipu O40Oxysterols receptor LXR-alpha / 0.744
3irx UDRGag-Pol polyprotein 2.7.7.49 0.744
3is9 AC7Gag-Pol polyprotein 2.7.7.49 0.744
3iw1 ASDSteroid C26-monooxygenase 1.14.13.141 0.744
3js2 VM1Fibroblast growth factor receptor 1 / 0.744
3jun AKDPhenazine biosynthesis protein A/B / 0.744
3jwe F4PMonoglyceride lipase / 0.744
3kk6 CELProstaglandin G/H synthase 1 1.14.99.1 0.744
3kro IPEGeranyl diphosphate synthase large subunit / 0.744
3kvx FMYMitogen-activated protein kinase 10 2.7.11.24 0.744
3kxo KXOHematopoietic prostaglandin D synthase / 0.744
3l08 ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 2.7.1.153 0.744
3l63 CAMCamphor 5-monooxygenase 1.14.15.1 0.744
3l70 JZVCytochrome b / 0.744
3l71 AZOCytochrome b / 0.744
3l9h EMQKinesin-like protein KIF11 / 0.744
3lg5 BTMEpi-isozizaene synthase 4.2.3.37 0.744
3lm4 HPXCatechol 2,3-dioxygenase / 0.744
3lp2 LP9Gag-Pol polyprotein 2.7.7.49 0.744
3lt0 FT1Enoyl-ACP reductase / 0.744
3lt1 FT2Enoyl-ACP reductase / 0.744
3lu8 IQXSerum albumin / 0.744
3lxi CAMCytochrome P450 / 0.744
3lz6 A0DCorticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.744
3mb7 14ICasein kinase II subunit alpha 2.7.11.1 0.744
3mdv CL6Cholesterol 24-hydroxylase / 0.744
3mfl DHYProtocatechuate 3,4-dioxygenase alpha chain 1.13.11.3 0.744
3mfl DHYProtocatechuate 3,4-dioxygenase beta chain 1.13.11.3 0.744
3mpa SB2Mitogen-activated protein kinase 14 / 0.744
3n3z IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A / 0.744
3n9j EAAGlutathione S-transferase P 2.5.1.18 0.744
3nal DBKCalcium-transporting ATPase / 0.744
3ndv NDVBeta-peptidyl aminopeptidase BapA / 0.744
3new 3NEMitogen-activated protein kinase 14 / 0.744
3nf7 CIWGag-Pol polyprotein / 0.744
3nfa CBJGag-Pol polyprotein / 0.744
3nfr EWQRibosyldihydronicotinamide dehydrogenase [quinone] / 0.744
3nhf VVVRibosyldihydronicotinamide dehydrogenase [quinone] / 0.744
3nhj A2ZRibosyldihydronicotinamide dehydrogenase [quinone] / 0.744
3nhl YTRRibosyldihydronicotinamide dehydrogenase [quinone] / 0.744
3nhr RZWRibosyldihydronicotinamide dehydrogenase [quinone] / 0.744
3nhx ASDSteroid Delta-isomerase 5.3.3.1 0.744
3nhy A7BRibosyldihydronicotinamide dehydrogenase [quinone] / 0.744
3nuv ASDSteroid Delta-isomerase 5.3.3.1 0.744
3o3n IRC(R)-2-hydroxyisocaproyl-CoA dehydratase alpha subunit / 0.744
3o8g O8GHTH-type transcriptional regulator EthR / 0.744
3obg SB2Mitogen-activated protein kinase 14 / 0.744
3ogw IMNLactoperoxidase 1.11.1.7 0.744
3oia A31Camphor 5-monooxygenase 1.14.15.1 0.744
3oji PYVAbscisic acid receptor PYL3 / 0.744
3oog YTPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.744
3oq1 3OQCorticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.744
3owx XRARibosyldihydronicotinamide dehydrogenase [quinone] / 0.744
3ox3 4X4Ribosyldihydronicotinamide dehydrogenase [quinone] / 0.744
3p5l IT5Carbonic anhydrase 2 4.2.1.1 0.744
3p6m DSOCamphor 5-monooxygenase 1.14.15.1 0.744
3p6n DSOCamphor 5-monooxygenase 1.14.15.1 0.744
3p6o ETGCamphor 5-monooxygenase 1.14.15.1 0.744
3p6p A6BCamphor 5-monooxygenase 1.14.15.1 0.744
3p9t TCLRepressor / 0.744
3pce 3HPProtocatechuate 3,4-dioxygenase alpha chain 1.13.11.3 0.744
3pce 3HPProtocatechuate 3,4-dioxygenase beta chain 1.13.11.3 0.744
3pcg 4HPProtocatechuate 3,4-dioxygenase alpha chain 1.13.11.3 0.744
3pcg 4HPProtocatechuate 3,4-dioxygenase beta chain 1.13.11.3 0.744
3py4 TYLLactoperoxidase 1.11.1.7 0.744
3q0v LL4HTH-type transcriptional regulator EthR / 0.744
3q5p TACMultidrug-efflux transporter 1 regulator / 0.744
3qsa TA7Anthranilate phosphoribosyltransferase / 0.744
3qwh KMP17beta-hydroxysteroid dehydrogenase / 0.744
3r6p A8SAbscisic acid receptor PYL10 / 0.744
3r7m SUZAldo-keto reductase family 1 member C3 / 0.744
3reo EUG(Iso)eugenol O-methyltransferase 2.1.1.146 0.744
3rgz BLDProtein BRASSINOSTEROID INSENSITIVE 1 2.7.10.1 0.744
3rj0 BLDProtein BRASSINOSTEROID INSENSITIVE 1 2.7.10.1 0.744
3rps 4B0Casein kinase II subunit alpha 2.7.11.1 0.744
3rqw ACHGamma-aminobutyric-acid receptor subunit beta-1 / 0.744
3sfi 3SFHTH-type transcriptional regulator EthR / 0.744
3sfy 3FYUncharacterized protein / 0.744
3sl8 JN7cAMP-specific 3',5'-cyclic phosphodiesterase 4D 3.1.4.53 0.744
3stw 2TDMethylketone synthase I / 0.744
3stx BKAMethylketone synthase I / 0.744
3svg ODRBromodomain-containing protein 4 / 0.744
3t2v KKJPeptidoglycan recognition protein 1 / 0.744
3t3q 9PLCytochrome P450 2A6 1.14.13 0.744
3t3r 9PLCytochrome P450 2A6 1.14.13 0.744
3tgy ASCLactoperoxidase 1.11.1.7 0.744
3tjs D0RCytochrome P450 3A4 / 0.744
3tp0 FO5HTH-type transcriptional regulator EthR / 0.744
3tvu B37Acetyl-CoA carboxylase / 0.744
3tvx PNXcAMP-specific 3',5'-cyclic phosphodiesterase 4A 3.1.4.53 0.744
3uba HC4Lactoperoxidase 1.11.1.7 0.744
3ue4 DB8Tyrosine-protein kinase ABL1 2.7.10.2 0.744
3ugr IMNAldo-keto reductase family 1 member C3 / 0.744
3uib SB2Putative mitogen-activated protein kinase / 0.744
3ujl A8SAbscisic acid receptor PYL2 / 0.744
3uku C69Actin-related protein 3 / 0.744
3ule C69Actin-related protein 3 / 0.744
3ut5 LOCTubulin beta chain / 0.744
3uu1 14BAnthranilate phosphoribosyltransferase / 0.744
3v35 NTIAldose reductase 1.1.1.21 0.744
3v4a PK1Androgen receptor / 0.744
3v94 WYQPhosphodiesterase / 0.744
3vhk BPKVascular endothelial growth factor receptor 2 2.7.10.1 0.744
3vn2 TLSPeroxisome proliferator-activated receptor gamma / 0.744
3vqd MOKPOL polyprotein / 0.744
3vw9 HPJLactoylglutathione lyase 4.4.1.5 0.744
3w1w CHDFerrochelatase, mitochondrial 4.99.1.1 0.744
3w2o 03PEpidermal growth factor receptor 2.7.10.1 0.744
3w5r LOAVitamin D3 receptor / 0.744
3w8z HTKPutative FAD-dependent oxygenase EncM / 0.744
3we4 5FIRibosomal protein S6 kinase beta-1 2.7.11.1 0.744
3wec AUICytochrome P450 / 0.744
3wip ACHAcetylcholine-binding protein / 0.744
3wqm B29Diterpene synthase 3.1.7.8 0.744
3wrh CAMCamphor 5-monooxygenase 1.14.15.1 0.744
3wrj CAMCamphor 5-monooxygenase 1.14.15.1 0.744
3wth IM4Acetylcholine-binding protein / 0.744
3wtj TH4Acetylcholine-binding protein / 0.744
3wtk TH4Acetylcholine-binding protein / 0.744
3zcw 4A2Kinesin-like protein KIF11 / 0.744
3zlw MT8Dual specificity mitogen-activated protein kinase kinase 1 2.7.12.2 0.744
3znq SS8D-amino-acid oxidase 1.4.3.3 0.744
3zv6 4HBCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase 1.3.1.56 0.744
3zyu 1GHBromodomain-containing protein 4 / 0.744
4a86 H35Major pollen allergen Bet v 1-A / 0.744
4a87 NARMajor pollen allergen Bet v 1-A / 0.744
4a9e 3PFBromodomain-containing protein 2 / 0.744
4a9h TVPBromodomain-containing protein 2 / 0.744
4a9l P9LBromodomain-containing protein 4 / 0.744
4a9n A9NBromodomain-containing protein 2 / 0.744
4a9o A9OBromodomain-containing protein 2 / 0.744
4ajm 3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 3.1.4.17 0.744
4alg 1GHBromodomain-containing protein 2 / 0.744
4asf 62UATP-dependent molecular chaperone HSP82 / 0.744
4b1f KRHGlutamate racemase / 0.744
4bb2 STRCorticosteroid-binding globulin / 0.744
4bbx LKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 3.1.4.17 0.744
4bc6 XZNSerine/threonine-protein kinase 10 2.7.11.1 0.744
4bcm T7ZCyclin-dependent kinase 2 2.7.11.22 0.744
4bdb ODOSerine/threonine-protein kinase Chk2 2.7.11.1 0.744
4bdd Z0OSerine/threonine-protein kinase Chk2 2.7.11.1 0.744
4bgg 844Activin receptor type-1 2.7.11.30 0.744
4bhz Z0BDual specificity protein kinase TTK 2.7.12.1 0.744
4bi1 ZO6Dual specificity protein kinase TTK 2.7.12.1 0.744
4bjx 73BBromodomain-containing protein 4 / 0.744
4bw1 S5BBromodomain-containing protein 4 / 0.744
4bw2 UTHBromodomain-containing protein 4 / 0.744
4bw3 9BMBromodomain-containing protein 4 / 0.744
4c1h X8ZMetallo-beta-lactamase type 2 / 0.744
4c66 H4CBromodomain-containing protein 4 / 0.744
4c67 L5SBromodomain-containing protein 4 / 0.744
4ce3 L4VATP-dependent molecular chaperone HSP82 / 0.744
4cf6 CBDNAD(P)H dehydrogenase [quinone] 1 1.6.5.2 0.744
4cfk LY2Bromodomain-containing protein 4 / 0.744
4cfl 8DQBromodomain-containing protein 4 / 0.744
4chz H75Integrase / 0.744
4cox IMNProstaglandin G/H synthase 2 1.14.99.1 0.744
4cp4 CAMCamphor 5-monooxygenase 1.14.15.1 0.744
4d0l 093Phosphatidylinositol 4-kinase beta 2.7.1.67 0.744
4da7 AC2Purine nucleoside phosphorylase DeoD-type 2.4.2.1 0.744
4dym IYZActivin receptor type-1 2.7.11.30 0.744
4dyp 0MSNucleoprotein / 0.744
4e4q RRHPeroxisome proliferator-activated receptor gamma / 0.744
4e5i 0N9Polymerase acidic protein / 0.744
4e5j 581Polymerase acidic protein / 0.744
4e73 0NRMitogen-activated protein kinase 8 2.7.11.24 0.744
4edz 0O5Hematopoietic prostaglandin D synthase / 0.744
4eh5 0OMMitogen-activated protein kinase 14 / 0.744
4eix NIMPhospholipase A2 VRV-PL-VIIIa / 0.744
4ejg NCTCytochrome P450 2A13 1.14.14.1 0.744
4ejh 0QACytochrome P450 2A13 1.14.14.1 0.744
4ek1 CAMCamphor 5-monooxygenase 1.14.15.1 0.744
4es5 MGTPolymerase basic protein 2 / 0.744
4exs X8ZMetallo-beta-lactamase type 2 / 0.744
4eyw L0RCarnitine O-palmitoyltransferase 2, mitochondrial 2.3.1.21 0.744
4ez7 2ANCyclin-dependent kinase 2 2.7.11.22 0.744
4f1t H52Probable serine/threonine-protein kinase roco4 2.7.11.1 0.744
4f3i 0S6Bromodomain-containing protein 4 / 0.744
4f6v ZYMDehydrosqualene synthase / 0.744
4fex 0TOAminoglycoside 3'-phosphotransferase AphA1-IAB / 0.744
4fiz CUE17beta-hydroxysteroid dehydrogenase / 0.744
4fj2 QSO17beta-hydroxysteroid dehydrogenase / 0.744
4fjy FJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 2.7.1.153 0.744
4flp JQ1Bromodomain testis-specific protein / 0.744
4foc 0UUALK tyrosine kinase receptor 2.7.10.1 0.744
4fv0 EK3Mitogen-activated protein kinase 1 2.7.11.24 0.744
4g2g TDHMycocyclosin synthase 1.14.21.9 0.744
4g3r CAMCamphor 5-monooxygenase 1.14.15.1 0.744
4gpj 0Q1Bromodomain-containing protein 4 / 0.744
4gr9 372Ribosyldihydronicotinamide dehydrogenase [quinone] / 0.744
4gtm 7TMProtein farnesyltransferase subunit beta 2.5.1.58 0.744
4gtr 7TRProtein farnesyltransferase subunit beta 2.5.1.58 0.744
4gtt 7TQGeranylgeranyl transferase type-2 subunit beta 2.5.1.60 0.744
4gtv 7TRGeranylgeranyl transferase type-2 subunit beta 2.5.1.60 0.744
4h38 0YXDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) 2.5.1.31 0.744
4h7c 10HAldo-keto reductase family 1 member C3 / 0.744
4hai I23Bifunctional epoxide hydrolase 2 3.1.3.76 0.744
4hee 14RPeroxisome proliferator-activated receptor gamma / 0.744
4hg7 NUTE3 ubiquitin-protein ligase Mdm2 6.3.2 0.744
4hge 15VTyrosine-protein kinase JAK2 / 0.744
4hkk AGITankyrase-2 2.4.2.30 0.744
4hus VIRVirginiamycin A acetyltransferase 2.3.1 0.744
4hxn 1A7Bromodomain-containing protein 4 / 0.744
4hxr 1A4Bromodomain-containing protein 4 / 0.744
4hxs 1A3Bromodomain-containing protein 4 / 0.744
4i22 IREEpidermal growth factor receptor 2.7.10.1 0.744
4i23 1C9Epidermal growth factor receptor 2.7.10.1 0.744
4i6f 1C7Serine/threonine-protein kinase PLK2 2.7.11.21 0.744
4i6h 1C8Serine/threonine-protein kinase PLK2 2.7.11.21 0.744
4i8v BHFCytochrome P450 1A1 1.14.14.1 0.744
4ict 1EDMycocyclosin synthase 1.14.21.9 0.744
4ifv FMQGag-Pol polyprotein 2.7.7.49 0.744
4ige CHJEnoyl-acyl carrier reductase / 0.744
4iks TFDMethionine aminopeptidase 1 / 0.744
4im2 BX7Serine/threonine-protein kinase TBK1 2.7.11.1 0.744
4ips 1G4Mycocyclosin synthase 1.14.21.9 0.744
4iw8 KN3Estrogen receptor / 0.744
4iz0 2BIGenome polyprotein 2.7.7.48 0.744
4j03 FVSBifunctional epoxide hydrolase 2 3.1.3.76 0.744
4j6b PLOCytochrome P450 monooxygenase / 0.744
4j6c STRCytochrome P450 monooxygenase / 0.744
4jbt ASDCytochrome P450 monooxygenase / 0.744
4jjk FOLFormate--tetrahydrofolate ligase / 0.744
4jpg 1OXPyruvate kinase PKM 2.7.1.40 0.744
4jq2 SUZAldo-keto reductase family 1 member C2 / 0.744
4jq4 IMNAldo-keto reductase family 1 member C2 / 0.744
4jwr 1MYE3 ubiquitin-protein ligase Mdm2 6.3.2 0.744
4jx1 CAMCamphor 5-monooxygenase 1.14.15.1 0.744
4jzr 4JREgl nine homolog 1 / 0.744
4k0y 1OASerine/threonine-protein kinase pim-1 2.7.11.1 0.744
4k18 1OBSerine/threonine-protein kinase pim-1 2.7.11.1 0.744
4k8a K8AFocal adhesion kinase 1 2.7.10.2 0.744
4k9u 5AWCytochrome P450 3A4 / 0.744
4kbk 1QGCasein kinase I isoform delta 2.7.11.1 0.744
4kfb 1QPGag-Pol polyprotein 2.7.7.49 0.744
4kko 1REGag-Pol polyprotein 2.7.7.49 0.744
4kky CAMCamphor 5-monooxygenase 1.14.15.1 0.744
4knj E1FCarbonic anhydrase 2 4.2.1.1 0.744
4l1x STRAldo-keto reductase family 1 member C2 / 0.744
4l42 5FIRibosomal protein S6 kinase beta-1 2.7.11.1 0.744
4l49 CAMCamphor 5-monooxygenase 1.14.15.1 0.744
4l4a CAMCamphor 5-monooxygenase 1.14.15.1 0.744
4l4c CAMCamphor 5-monooxygenase 1.14.15.1 0.744
4l4d CAMCamphor 5-monooxygenase 1.14.15.1 0.744
4l4e CAMCamphor 5-monooxygenase 1.14.15.1 0.744
4l4f CAMCamphor 5-monooxygenase 1.14.15.1 0.744
4la0 198Serum albumin / 0.744
4lb2 DM5Serum albumin / 0.744
4lga A2OAbscisic acid receptor PYL2 / 0.744
4llk MEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 3.1.4.17 0.744
4lsl 1YQGag-Pol polyprotein 2.7.7.49 0.744
4lvt 1XJApoptosis regulator Bcl-2 / 0.744
4m11 MXMProstaglandin G/H synthase 2 1.14.99.1 0.744
4men 25KBromodomain-containing protein 4 / 0.744
4mm7 29JNa(+):neurotransmitter symporter (Snf family) / 0.744
4mp2 PV1[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial 2.7.11.2 0.744
4mqy 2CWUDP-3-O-acyl-N-acetylglucosamine deacetylase / 0.744
4muw 2F4cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 3.1.4.17 0.744
4mxo DB8Proto-oncogene tyrosine-protein kinase Src 2.7.10.2 0.744
4mxy DB8Proto-oncogene tyrosine-protein kinase Src 2.7.10.2 0.744
4mxz DB8Proto-oncogene tyrosine-protein kinase Src 2.7.10.2 0.744
4n16 CHDCarbonic anhydrase 2 4.2.1.1 0.744
4nak PBQ2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic 2.7.7.60 0.744
4nb6 444Nuclear receptor ROR-gamma / 0.744
4nky 3QZSteroid 17-alpha-hydroxylase/17,20 lyase / 0.744
4npt 017Protease / 0.744
4nqm Y1ZBromodomain-containing protein 4 / 0.744
4nra 2LWBromodomain adjacent to zinc finger domain protein 2B / 0.744
4nt3 ZAWLactoperoxidase 1.11.1.7 0.744
4oj4 DIFPeroxisome proliferator-activated receptor gamma / 0.744
4otw DB8Receptor tyrosine-protein kinase erbB-3 2.7.10.1 0.744
4py6 R78Bromodomain protein, putative / 0.744
4qmn DB8Serine/threonine-protein kinase 24 2.7.11.1 0.744
4qmx H8HSerine/threonine-protein kinase 24 2.7.11.1 0.744
4qzs JQ1Bromodomain-containing protein 4 / 0.744
4qzu RTLRetinol-binding protein 2 / 0.744
4r21 STRCytochrome P450 family 17 polypeptide 2 / 0.744
4ra3 TFXBeta-2-microglobulin / 0.744
4rrx LURProstaglandin G/H synthase 2 1.14.99.1 0.744
4rw4 494Gag-Pol polyprotein 2.7.7.49 0.744
4rw6 494Gag-Pol polyprotein 2.7.7.49 0.744
4std BFSScytalone dehydratase 4.2.1.94 0.744
4tln LNOThermolysin 3.4.24.27 0.744
4tqq UQ1Reaction center protein L chain / 0.744
4uyg 73BBromodomain-containing protein 2 / 0.744
4v26 TF3[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial 2.7.11.2 0.744
4wfr 2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase 3.1.4.37 0.744
4xo7 ASDAldo-keto reductase family 1 member C2 / 0.744
4xqg 1PSHomospermidine synthase 2.5.1.44 0.744
4ytn FD8Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial / 0.744
4ytn FD8Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial / 0.744
4ytn FD8Succinate dehydrogenase cytochrome b560 / 0.744
5c8d 5ADProbable transcriptional regulator / 0.744
5cp4 CAMCamphor 5-monooxygenase 1.14.15.1 0.744
5d8u 0N8Polymerase acidic protein / 0.744
5eq1 BEAPeregrin / 0.744
5hs1 VORLanosterol 14-alpha demethylase / 0.744
5ikr ID8Prostaglandin G/H synthase 2 1.14.99.1 0.744
5it1 2OHPutative cytochrome P450 / 0.744
5itz LOCTubulin beta-2B chain / 0.744
5iw5 NMNNADH pyrophosphatase / 0.744
5liu 388Aldo-keto reductase family 1 member B10 1.1.1 0.744
5pah LDPPhenylalanine-4-hydroxylase 1.14.16.1 0.744
6cp4 CAMCamphor 5-monooxygenase 1.14.15.1 0.744
5l7i VISSmoothened homolog / 0.744
4k5y 1Q5Corticotropin-releasing factor receptor 1 / 0.744
4s0v SUVOrexin receptor type 2 / 0.744
4ntj AZJP2Y purinoceptor 12 / 0.744
4u16 3C0Muscarinic acetylcholine receptor M3 / 0.744
3rey XACAdenosine receptor A2a / 0.744
3rfm CFFAdenosine receptor A2a / 0.744
3uza T4GAdenosine receptor A2a / 0.744
2w03 ADNAcsD / 0.715
3sr4 TT8Histone-lysine N-methyltransferase, H3 lysine-79 specific 2.1.1.43 0.707
3qow SAMHistone-lysine N-methyltransferase, H3 lysine-79 specific 2.1.1.43 0.706
2nq7 HM5Methionine aminopeptidase 1 / 0.691
2vcx D26Hematopoietic prostaglandin D synthase / 0.691
2wey EV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 3.1.4.17 0.691
3wi2 P98cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 3.1.4.17 0.691
4hxx 1AYMethionine aminopeptidase 1 / 0.691
4ikr PVPMethionine aminopeptidase 1 / 0.691
4ikt TFVMethionine aminopeptidase 1 / 0.691
4iku SHXMethionine aminopeptidase 1 / 0.691
1nbi SAMGlycine N-methyltransferase 2.1.1.20 0.685
3g1o RF1HTH-type transcriptional regulator EthR / 0.681
1nw3 SAMHistone-lysine N-methyltransferase, H3 lysine-79 specific 2.1.1.43 0.679
2eg5 SAH7-methylxanthosine synthase 1 / 0.679
5ccx SAHtRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A 2.1.1.220 0.677
4uy6 SAHHistidine N-alpha-methyltransferase / 0.676
5fa5 MTAProtein arginine N-methyltransferase 5 / 0.675
2i9k SAHModification methylase HhaI 2.1.1.37 0.674
3mht SAHModification methylase HhaI 2.1.1.37 0.672
4poo SAMPutative RNA methylase / 0.672
7mht SAHModification methylase HhaI 2.1.1.37 0.672
3dlc SAMSAM (And some other nucleotide) binding motif:Generic methyltransferase / 0.671
1rjg SAHLeucine carboxyl methyltransferase 1 2.1.1.233 0.669
2np6 NEAModification methylase TaqI 2.1.1.72 0.669
3g07 SAM7SK snRNA methylphosphate capping enzyme 2.1.1 0.669
4u7t SAHDNA (cytosine-5)-methyltransferase 3A 2.1.1.37 0.669
4yac NAIC alpha-dehydrogenase / 0.669
1kia SAMGlycine N-methyltransferase 2.1.1.20 0.668
3ru9 NADUDP-N-acetylglucosamine 4-epimerase / 0.668
3lcc SAHThiocyanate methyltransferase 1 / 0.667
4nbu NAI3-oxoacyl-(Acyl-carrier-protein) reductase / 0.667
1skm SAHModification methylase HhaI 2.1.1.37 0.666
1uay ADNOxidoreductase / 0.666
3o15 IFPThiamine-phosphate synthase / 0.666
3ou6 SAMSAM-dependent methyltransferase / 0.666
1gad NADGlyceraldehyde-3-phosphate dehydrogenase A / 0.665
3eey SAMrRNA methylase / 0.665
1g6c IFPThiamine-phosphate synthase / 0.664
1i3l NADUDP-glucose 4-epimerase / 0.664
1lkd BP6Biphenyl-2,3-diol 1,2-dioxygenase 1.13.11.39 0.664
1y8q ATPSUMO-activating enzyme subunit 2 6.3.2 0.664
2p35 SAHTrans-aconitate 2-methyltransferase / 0.664
1iy8 NADLevodione reductase / 0.663
1kmy BPYBiphenyl-2,3-diol 1,2-dioxygenase 1.13.11.39 0.663
1lgt BP3Biphenyl-2,3-diol 1,2-dioxygenase 1.13.11.39 0.663
2c7q SAHModification methylase HhaI 2.1.1.37 0.663
2ibt NEAModification methylase TaqI 2.1.1.72 0.663
3go4 SAHUncharacterized protein / 0.663
1d2h SAHGlycine N-methyltransferase 2.1.1.20 0.662
2ih2 NEAModification methylase TaqI 2.1.1.72 0.662
3ruf NADUDP-N-acetylglucosamine 4-epimerase / 0.662
2bgm NAJSecoisolariciresinol dehydrogenase 1.1.1.331 0.661
4nbw NADShort-chain dehydrogenase/reductase SDR / 0.661
4wec NADShort chain dehydrogenase / 0.661
1afs TES3-alpha-hydroxysteroid dehydrogenase 1.1.1.50 0.660
1bzs BSINeutrophil collagenase 3.4.24.34 0.660
1e3v DXCSteroid Delta-isomerase 5.3.3.1 0.660
1fml RTLRetinol dehydratase / 0.660
1g3m PCQEstrogen sulfotransferase 2.8.2.4 0.660
1gm7 PNNPenicillin G acylase 3.5.1.11 0.660
1gw2 FERPeroxidase C1A 1.11.1.7 0.660
1h60 STRPentaerythritol tetranitrate reductase / 0.660
1h62 ANBPentaerythritol tetranitrate reductase / 0.660
1hy7 MBSStromelysin-1 3.4.24.17 0.660
1nen DNTSuccinate dehydrogenase iron-sulfur subunit 1.3.5.1 0.660
1nen DNTSuccinate dehydrogenase cytochrome b556 subunit / 0.660
1ove 358Mitogen-activated protein kinase 14 / 0.660
1phq FPE2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.660
1tou B1VFatty acid-binding protein, adipocyte / 0.660
1uyr D1LAcetyl-CoA carboxylase / 0.660
1uys H1LAcetyl-CoA carboxylase / 0.660
1xom CIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D 3.1.4.53 0.660
1ya3 STRMineralocorticoid receptor / 0.660
1yb1 AOIEstradiol 17-beta-dehydrogenase 11 1.1.1.62 0.660
1you PFDCollagenase 3 3.4.24 0.660
1zem NADXylitol dehydrogenase / 0.660
2a1h GBNBranched-chain-amino-acid aminotransferase, mitochondrial 2.6.1.42 0.660
2aa5 STRMineralocorticoid receptor / 0.660
2aie SB9Peptide deformylase / 0.660
2brl POOGenome polyprotein 2.7.7.48 0.660
2bzs CB1Ribosyldihydronicotinamide dehydrogenase [quinone] / 0.660
2evc FC3Methionine aminopeptidase / 0.660
2evm FC2Methionine aminopeptidase / 0.660
2f2k TGGAldose reductase 1.1.1.21 0.660
2f4b EHAPeroxisome proliferator-activated receptor gamma / 0.660
2fhy A37Fructose-1,6-bisphosphatase 1 3.1.3.11 0.660
2flh ZEACytokinin-specific binding protein / 0.660
2fm0 M98cAMP-specific 3',5'-cyclic phosphodiesterase 4D 3.1.4.53 0.660
2gfk VIIMetallo-beta-lactamase L1 type 3 / 0.660
2j2p SC2Ficolin-2 / 0.660
2lba CHOFatty acid binding protein 6 / 0.660
2nsd 4PIEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.660
2ow2 8MRMatrix metalloproteinase-9 3.4.24.35 0.660
2oyf IACBasic phospholipase A2 VRV-PL-VIIIa 3.1.1.4 0.660
2p2f COAAcetyl-coenzyme A synthetase / 0.660
2q5p 241Peroxisome proliferator-activated receptor gamma / 0.660
2q92 B23Methionine aminopeptidase / 0.660
2q93 B21Methionine aminopeptidase / 0.660
2q94 A04Methionine aminopeptidase / 0.660
2qds MCOMetallo-beta-lactamase type 2 / 0.660
2qfo A51Heat shock protein HSP 90-alpha / 0.660
2qo4 CHDFatty acid-binding protein 10-A, liver basic / 0.660
2qo6 CHDFatty acid-binding protein 10-A, liver basic / 0.660
2r3g SC9Cyclin-dependent kinase 2 2.7.11.22 0.660
2rlc CHDCholoylglycine hydrolase 3.5.1.24 0.660
2rm2 W43Genome polyprotein / 0.660
2uzf CAA1,4-dihydroxy-2-naphthoyl-CoA synthase / 0.660
2vb8 TLM3-oxoacyl-[acyl-carrier-protein] synthase 1 2.3.1.41 0.660
2w8y 486Progesterone receptor / 0.660
2wdq CBESuccinate dehydrogenase iron-sulfur subunit 1.3.5.1 0.660
2wdq CBESuccinate dehydrogenase cytochrome b556 subunit / 0.660
2wgg TLM3-oxoacyl-[acyl-carrier-protein] synthase 1 2.3.1.41 0.660
2wp9 CBESuccinate dehydrogenase iron-sulfur subunit 1.3.5.1 0.660
2wp9 CBESuccinate dehydrogenase cytochrome b556 subunit / 0.660
2wu2 CBESuccinate dehydrogenase iron-sulfur subunit 1.3.5.1 0.660
2wu2 CBESuccinate dehydrogenase cytochrome b556 subunit / 0.660
2xwy IB8Genome polyprotein 2.7.7.48 0.660
2yog 74XThymidylate kinase / 0.660
2yoh WMJThymidylate kinase / 0.660
2z2d HSIMacrophage metalloelastase 3.4.24.65 0.660
2zb8 IMNProstaglandin reductase 2 1.3.1.48 0.660
3a25 SAMtRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase / 0.660
3ae4 N1MSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial 1.3.5.1 0.660
3ae4 N1MSuccinate dehydrogenase cytochrome b560 subunit, mitochondrial / 0.660
3b99 U51Prostacyclin synthase / 0.660
3c10 TSNHistone deacetylase 7 3.5.1.98 0.660
3gc9 B45Mitogen-activated protein kinase 11 2.7.11.24 0.660
3gnc QQQGlutaryl-CoA dehydrogenase / 0.660
3h1j SMACytochrome b / 0.660
3h6v NS6Glutamate receptor 2 / 0.660
3hll I45Mitogen-activated protein kinase 14 / 0.660
3hp2 P36Mitogen-activated protein kinase 14 / 0.660
3hp5 52PMitogen-activated protein kinase 14 / 0.660
3hub 469Mitogen-activated protein kinase 14 / 0.660
3hx3 RETRetinaldehyde-binding protein 1 / 0.660
3i58 7NA2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase / 0.660
3i97 8DRNeuropilin-1 / 0.660
3ime BZ2Pantothenate synthetase 6.3.2.1 0.660
3iu7 FCDMethionine aminopeptidase 2 / 0.660
3iw5 DF3Mitogen-activated protein kinase 14 / 0.660
3iw6 PP0Mitogen-activated protein kinase 14 / 0.660
3iw7 IPKMitogen-activated protein kinase 14 / 0.660
3juq AKDPhenazine biosynthesis protein A/B / 0.660
3jxw LXGSerine/threonine-protein kinase pim-1 2.7.11.1 0.660
3k3k A8SAbscisic acid receptor PYR1 / 0.660
3k4s 0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D 3.1.4.53 0.660
3kb0 A8SAbscisic acid receptor PYL2 / 0.660
3mg3 ECHOrange carotenoid-binding protein / 0.660
3myt EQUSteroid Delta-isomerase 5.3.3.1 0.660
3n8x NIMProstaglandin G/H synthase 1 1.14.99.1 0.660
3nbr ASDSteroid Delta-isomerase 5.3.3.1 0.660
3nmv PYVAbscisic acid receptor PYL2 / 0.660
3nr4 PYVAbscisic acid receptor PYL2 / 0.660
3nx2 FERFerulic acid decarboxylase / 0.660
3ofm 4B0Casein kinase II subunit alpha' 2.7.11.1 0.660
3p2h NOOAcyl-homoserine-lactone synthase / 0.660
3p3z P3ZPutative cytochrome P450 / 0.660
3pe6 ZYHMonoglyceride lipase / 0.660
3pm0 BHFCytochrome P450 1B1 / 0.660
3qci NX3Receptor-type tyrosine-protein phosphatase gamma 3.1.3.48 0.660
3ql6 NIMLactoperoxidase 1.11.1.7 0.660
3qs8 17DAnthranilate phosphoribosyltransferase / 0.660
3r58 NPSAldo-keto reductase family 1 member C3 / 0.660
3r8g IZPAldo-keto reductase family 1 member C3 / 0.660
3r8h ZOMAldo-keto reductase family 1 member C3 / 0.660
3r94 FLRAldo-keto reductase family 1 member C3 / 0.660
3roc 29AMitogen-activated protein kinase 14 / 0.660
3sh0 SAXDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) 2.5.1.31 0.660
3stu DK3Methylketone synthase I / 0.660
3th8 TH9Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) 2.5.1.31 0.660
3tz3 B36Acetyl-CoA carboxylase / 0.660
3ufy NPXAldo-keto reductase family 1 member C3 / 0.660
3ug8 IMNAldo-keto reductase family 1 member C3 / 0.660
3uzz ASD3-oxo-5-beta-steroid 4-dehydrogenase / 0.660
3vrb FTNSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial / 0.660
3vrb FTNCytochrome b-large subunit / 0.660
3vsp EK8Peroxisome proliferator-activated receptor gamma / 0.660
3wiy LC6Induced myeloid leukemia cell differentiation protein Mcl-1 / 0.660
3zsh 469Mitogen-activated protein kinase 14 / 0.660
4a4v YFDPeroxisome proliferator-activated receptor gamma / 0.660
4a4w YFBPeroxisome proliferator-activated receptor gamma / 0.660
4a9m P9MBromodomain-containing protein 2 / 0.660
4alh A9PBromodomain-containing protein 2 / 0.660
4bft ZVTPantothenate kinase 2.7.1.33 0.660
4bfx ZVXPantothenate kinase 2.7.1.33 0.660
4bs4 A64Tankyrase-2 2.4.2.30 0.660
4c3y ANB3-ketosteroid dehydrogenase / 0.660
4c6u TLG3-oxoacyl-ACP synthase / 0.660
4c6z TLE3-oxoacyl-ACP synthase / 0.660
4dsc A8SAbscisic acid receptor PYL3 / 0.660
4e5f 0N7Polymerase acidic protein / 0.660
4e5h 0N8Polymerase acidic protein / 0.660
4eji 0QACytochrome P450 2A13 1.14.14.1 0.660
4er7 AW3Histone-lysine N-methyltransferase, H3 lysine-79 specific 2.1.1.43 0.660
4f1l 0RYPoly [ADP-ribose] polymerase 14 2.4.2.30 0.660
4fal 0T0Aldo-keto reductase family 1 member C3 / 0.660
4hki FLNTankyrase-2 2.4.2.30 0.660
4hl5 15WTankyrase-2 2.4.2.30 0.660
4hlh 20DTankyrase-2 2.4.2.30 0.660
4hlk 431Tankyrase-2 2.4.2.30 0.660
4hlm 16STankyrase-2 2.4.2.30 0.660
4hmn 16JAldo-keto reductase family 1 member C3 / 0.660
4hmv WUBPhenazine biosynthesis protein PhzG 1.4 0.660
4hxo 1A6Bromodomain-containing protein 4 / 0.660
4i7f NVEGag-Pol polyprotein 2.7.7.49 0.660
4imo PWZProstaglandin-H2 D-isomerase 5.3.99.2 0.660
4iv8 SAMPhosphoethanolamine N-methyltransferase,putative / 0.660
4jda A9SAbscisic acid receptor PYL3 / 0.660
4jq1 NPSAldo-keto reductase family 1 member C2 / 0.660
4jq3 ZOMAldo-keto reductase family 1 member C2 / 0.660
4jtq FLPAldo-keto reductase family 1 member C2 / 0.660
4jtr IBPAldo-keto reductase family 1 member C2 / 0.660
4jv6 18FRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta / 0.660
4jvm XDIEstrogen sulfotransferase 2.8.2.4 0.660
4jvn YUGEstrogen sulfotransferase 2.8.2.4 0.660
4l0i 1UWTankyrase-2 2.4.2.30 0.660
4l0s 1UZTankyrase-2 2.4.2.30 0.660
4l0t 1V0Tankyrase-2 2.4.2.30 0.660
4l0v 1V1Tankyrase-2 2.4.2.30 0.660
4l10 A63Tankyrase-2 2.4.2.30 0.660
4l2f 1V3Tankyrase-2 2.4.2.30 0.660
4l31 F08Tankyrase-2 2.4.2.30 0.660
4l32 1VFTankyrase-2 2.4.2.30 0.660
4l34 1VGTankyrase-2 2.4.2.30 0.660
4lrg 1XBBromodomain-containing protein 4 / 0.660
4m83 ERYOleandomycin glycosyltransferase 2.4.1 0.660
4nhk PD2Prolyl 3,4-dihydroxylase TPA1 1.14.11 0.660
4nr5 2LLCREB-binding protein / 0.660
4ot2 NPSSerum albumin / 0.660
4oty LURProstaglandin G/H synthase 2 1.14.99.1 0.660
4psb GA3Cytokinin-specific binding protein / 0.660
4pv5 CBWLactoylglutathione lyase 4.4.1.5 0.660
4q0a 4OAVitamin D3 receptor A / 0.660
4trj 665Enoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.660
4tzk 641Enoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.660
4tzt 468Enoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.660
4u0j 566Enoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.660
4wev SUZAldo-keto reductase family 1 member B10 1.1.1 0.660
4xuh SFIPeroxisome proliferator-activated receptor gamma / 0.660
4xum IMNPeroxisome proliferator-activated receptor gamma / 0.660
4zbr NPSSerum albumin / 0.660
5dfc EAMBromodomain-containing protein 2 / 0.660
5fdg 0N8Polymerase acidic protein / 0.660
5fkk TDCTetracycline repressor protein class D / 0.660
5je2 SAHMethyl transferase / 0.660
1ek5 NADUDP-glucose 4-epimerase / 0.659
1orr NADCDP-paratose 2-epimerase / 0.659
3a27 SAMtRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase / 0.659
3fri SAH16S rRNA methylase / 0.659
3rua NADUDP-N-acetylglucosamine 4-epimerase / 0.659
3uj7 SAMPhosphoethanolamine N-methyltransferase / 0.659
4c1i EH9cGMP-dependent 3',5'-cyclic phosphodiesterase 3.1.4.17 0.659
4jhi EMUNodulin-13 / 0.659
5je4 SAHMethyl transferase / 0.659
1wy7 SAHUncharacterized protein / 0.658
3q87 SAMN6 ADENINE SPECIFIC DNA METHYLASE (METHYLTRANSFERASE SUPERFAMILY) / 0.658
3sx2 NADUncharacterized protein / 0.658
4yai NAIC alpha-dehydrogenase / 0.658
2bh2 SAH23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD / 0.657
2p5u NADUDP-glucose 4-epimerase / 0.657
3nug NADPyridoxal 4-dehydrogenase 1.1.1.107 0.657
4ajg F07cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 3.1.4.17 0.657
5bp9 SAHPutative methyltransferase protein / 0.657
5jdz SAHMethyl transferase / 0.657
2bns MSTReaction center protein L chain / 0.656
2gdz NAD15-hydroxyprostaglandin dehydrogenase [NAD(+)] 1.1.1.141 0.656
3epp SFGmRNA cap guanine-N7 methyltransferase 2.1.1.56 0.656
4fgz SAHPhosphoethanolamine N-methyltransferase / 0.656
1hwl ADP3-hydroxy-3-methylglutaryl-coenzyme A reductase 1.1.1.34 0.655
2b69 NADUDP-glucuronic acid decarboxylase 1 4.1.1.35 0.655
2bnp MSTReaction center protein L chain / 0.655
2hmv ADPKtr system potassium uptake protein A / 0.655
2o07 MTASpermidine synthase 2.5.1.16 0.655
4ekg 0QJHistone-lysine N-methyltransferase, H3 lysine-79 specific 2.1.1.43 0.655
4gh5 NADShort-chain dehydrogenase/reductase SDR / 0.655
5je3 SAHMethyl transferase / 0.655
1bdb NADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase / 0.654
3pgx NADUncharacterized NAD-dependent oxidoreductase MAP_4146 / 0.654
3wv8 ATPHmd co-occurring protein HcgE / 0.654
4eki 0QKHistone-lysine N-methyltransferase, H3 lysine-79 specific 2.1.1.43 0.654
4qnu GEKtRNA U34 carboxymethyltransferase / 0.654
4yag NAIC alpha-dehydrogenase / 0.654
2q1w NADPutative nucleotide sugar epimerase/ dehydratase / 0.653
3iv6 SAMUncharacterized protein / 0.653
3tm4 SAMUncharacterized protein / 0.653
4g47 TZFMycocyclosin synthase 1.14.21.9 0.653
4hh4 SAHCcbJ / 0.653
1nbh SAMGlycine N-methyltransferase 2.1.1.20 0.652
2ag5 NAD3-hydroxybutyrate dehydrogenase type 2 / 0.652
2okc SAMProbable type I restriction enzyme BthVORF4518P M protein 2.1.1.72 0.652
2p5y NADUDP-glucose 4-epimerase / 0.652
3grr SAHProbable ribosomal RNA small subunit methyltransferase A / 0.652
3sso SAHMycinamicin VI 2''-O-methyltransferase / 0.652
1e3s NAD3-hydroxyacyl-CoA dehydrogenase type-2 1.1.1.35 0.651
1kvr NADUDP-glucose 4-epimerase 5.1.3.2 0.651
1wg8 SAMRibosomal RNA small subunit methyltransferase H / 0.651
3ko8 NADNAD-dependent epimerase/dehydratase / 0.651
3uj8 SFGPhosphoethanolamine N-methyltransferase / 0.651
4rtj SFGDNA adenine methylase 2.1.1.72 0.651
5jr3 SAHCarminomycin 4-O-methyltransferase DnrK 2.1.1.292 0.651
1geg NADDiacetyl reductase [(S)-acetoin forming] 1.1.1.304 0.650
2zzm SAMtRNA (guanine(37)-N1)-methyltransferase Trm5b 2.1.1.228 0.650
4qnv GEKtRNA U34 carboxymethyltransferase / 0.650
5ig2 NADShort-chain dehydrogenase/reductase SDR / 0.650