sc-PDB

List of CHEMBLId :

This value allows a number of roughly comparable measures of half-maximal response concentration/potency/affinity to be compared on a negative logarithmic scale (e.g., an IC50 measurement of 1nM would have a pChEMBL value of 9).

Uniprot Annotation

Name:	Bromodomain-containing protein 2
ID:	BRD2_HUMAN
AC:	P25440
Organism:	Homo sapiens
Reign:	Eukaryota
TaxID:	9606
EC Number:	/

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Chains:

Chain Name:	Percentage of Residues within binding site
A	11 %
C	89 %

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Ligand binding site composition:

B-Factor:	39.468
Number of residues:	19
Including
Standard Amino Acids:	18
Non Standard Amino Acids:	0
Water Molecules:	1
Cofactors:
Metals:

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Cavity properties

Ligandability	Volume (Å3)
1.385	712.125

% Hydrophobic	% Polar
59.24	40.76
According to VolSite

HET Code:	A9P
Formula:	C11H11NO
Molecular weight:	173.211 g/mol
DrugBank ID:	-
Buried Surface Area:	53.2 %
Polar Surface area:	26.03 Å2

Number of
H-Bond Acceptors:	1
H-Bond Donors:	0
Rings:	2
Aromatic rings:	2
Anionic atoms:	0
Cationic atoms:	0
Rule of Five Violation:	0
Rotatable Bonds:	1

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Mass center Coordinates

X	Y	Z
0.522	7.80769	21.6128

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