sc-PDB

List of CHEMBLId :

This value allows a number of roughly comparable measures of half-maximal response concentration/potency/affinity to be compared on a negative logarithmic scale (e.g., an IC50 measurement of 1nM would have a pChEMBL value of 9).

Uniprot Annotation

Name:	Protein arginine N-methyltransferase 5
ID:	ANM5_HUMAN
AC:	O14744
Organism:	Homo sapiens
Reign:	Eukaryota
TaxID:	9606
EC Number:	/

---

Chains:

Chain Name:	Percentage of Residues within binding site
A	100 %
C	0 %

---

Ligand binding site composition:

B-Factor:	51.098
Number of residues:	30
Including
Standard Amino Acids:	28
Non Standard Amino Acids:	0
Water Molecules:	2
Cofactors:
Metals:

---

Cavity properties

Ligandability	Volume (Å3)
0.690	340.875

% Hydrophobic	% Polar
59.41	40.59
According to VolSite

HET Code:	MTA
Formula:	C11H15N5O3S
Molecular weight:	297.333 g/mol
DrugBank ID:	DB02282
Buried Surface Area:	77.92 %
Polar Surface area:	144.61 Å2

Number of
H-Bond Acceptors:	8
H-Bond Donors:	3
Rings:	3
Aromatic rings:	2
Anionic atoms:	0
Cationic atoms:	0
Rule of Five Violation:	0
Rotatable Bonds:	3

---

Mass center Coordinates

X	Y	Z
-16.5497	-101.011	-3.908

• 2D View
• 3D View