sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5fa5 | MTA | Protein arginine N-methyltransferase 5 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 5fa5 | MTA | Protein arginine N-methyltransferase 5 | / | 1.000 | |
| 4g56 | SAH | Protein arginine N-methyltransferase 5 | / | 0.570 | |
| 3ua3 | SAH | Protein arginine N-methyltransferase 5 | / | 0.536 | |
| 4gqb | 0XU | Protein arginine N-methyltransferase 5 | / | 0.502 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.458 | |
| 3fri | SAH | 16S rRNA methylase | / | 0.457 | |
| 3zdu | 38R | Cyclin-dependent kinase-like 3 | 2.7.11.22 | 0.453 | |
| 3wv7 | ADP | Hmd co-occurring protein HcgE | / | 0.450 | |
| 3l9l | L9L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 4cjs | L0Y | Integrase | / | 0.448 | |
| 3l9m | L9M | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 4pyo | SAH | Catechol O-methyltransferase | 2.1.1.6 | 0.447 | |
| 2qf2 | GDP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.446 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.446 | |
| 1nw5 | SAM | Modification methylase RsrI | 2.1.1.72 | 0.445 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.445 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 4ftc | H6K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2qta | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.443 | |
| 1xzq | FON | tRNA modification GTPase MnmE | 3.6.5 | 0.442 | |
| 2p2q | PRX | Acetyl-coenzyme A synthetase | / | 0.442 | |
| 2xvu | 9DN | Serum albumin | / | 0.442 | |
| 4c05 | SAH | Protein arginine N-methyltransferase 6 | / | 0.442 | |
| 4kdr | SAH | Ubiquinone biosynthesis O-methyltransferase | / | 0.441 | |
| 1nv9 | SAH | Release factor glutamine methyltransferase | 2.1.1.297 | 0.440 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.440 | |
| 4yuz | S4M | Spermidine synthase, putative | / | 0.440 |