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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
5fa5MTAProtein arginine N-methyltransferase 5

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
5fa5MTAProtein arginine N-methyltransferase 5/1.000
4g56SAHProtein arginine N-methyltransferase 5/0.519
3ua3SAHProtein arginine N-methyltransferase 5/0.502
4gqb0XUProtein arginine N-methyltransferase 5/0.470
3zdu38RCyclin-dependent kinase-like 32.7.11.220.459
1xzqFONtRNA modification GTPase MnmE3.6.50.446
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
1p0pBCHCholinesterase3.1.1.80.440