sc-PDB

List of CHEMBLId :

This value allows a number of roughly comparable measures of half-maximal response concentration/potency/affinity to be compared on a negative logarithmic scale (e.g., an IC50 measurement of 1nM would have a pChEMBL value of 9).

Uniprot Annotation

Name:	Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase
ID:	MCE_VACCW
AC:	P07617
Organism:	Vaccinia virus )
Reign:	Viruses
TaxID:	10254
EC Number:	2.1.1.57

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Chains:

Chain Name:	Percentage of Residues within binding site
A	100 %

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Ligand binding site composition:

B-Factor:	23.553
Number of residues:	18
Including
Standard Amino Acids:	17
Non Standard Amino Acids:	0
Water Molecules:	1
Cofactors:
Metals:

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Cavity properties

Ligandability	Volume (Å3)
0.835	320.625

% Hydrophobic	% Polar
60.00	40.00
According to VolSite

HET Code:	MG7
Formula:	C11H16N5O5
Molecular weight:	298.275 g/mol
DrugBank ID:	DB03493
Buried Surface Area:	37.51 %
Polar Surface area:	146.21 Å2

Number of
H-Bond Acceptors:	7
H-Bond Donors:	5
Rings:	3
Aromatic rings:	1
Anionic atoms:	0
Cationic atoms:	1
Rule of Five Violation:	0
Rotatable Bonds:	2

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Mass center Coordinates

X	Y	Z
16.5256	11.9971	22.8379

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