sc-PDB

List of CHEMBLId :

This value allows a number of roughly comparable measures of half-maximal response concentration/potency/affinity to be compared on a negative logarithmic scale (e.g., an IC50 measurement of 1nM would have a pChEMBL value of 9).

Uniprot Annotation

Name:	Methionine aminopeptidase 1
ID:	MAP11_HUMAN
AC:	P53582
Organism:	Homo sapiens
Reign:	Eukaryota
TaxID:	9606
EC Number:	/

---

Chains:

Chain Name:	Percentage of Residues within binding site
A	100 %

---

Ligand binding site composition:

B-Factor:	40.586
Number of residues:	32
Including
Standard Amino Acids:	32
Non Standard Amino Acids:	0
Water Molecules:	0
Cofactors:
Metals:

---

Cavity properties

Ligandability	Volume (Å3)
0.539	297.000

% Hydrophobic	% Polar
55.68	44.32
According to VolSite

HET Code:	1AY
Formula:	C28H30Cl2N5
Molecular weight:	507.477 g/mol
DrugBank ID:	-
Buried Surface Area:	42.4 %
Polar Surface area:	67.31 Å2

Number of
H-Bond Acceptors:	4
H-Bond Donors:	2
Rings:	4
Aromatic rings:	4
Anionic atoms:	0
Cationic atoms:	1
Rule of Five Violation:	2
Rotatable Bonds:	11

---

Mass center Coordinates

X	Y	Z
20.8104	19.3374	18.5115

• 2D View
• 3D View