Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4hxx1AYMethionine aminopeptidase 1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4hxx1AYMethionine aminopeptidase 1/1.000
4iktTFVMethionine aminopeptidase 1/0.741
4fliY16Methionine aminopeptidase 1/0.707
4ikrPVPMethionine aminopeptidase 1/0.669
3pkeY10Methionine aminopeptidase 2/0.646
4ikuSHXMethionine aminopeptidase 1/0.639
3iu7FCDMethionine aminopeptidase 2/0.631
3pkdY10Methionine aminopeptidase 2/0.622
2nq7HM5Methionine aminopeptidase 1/0.621
4fllYZ6Methionine aminopeptidase 1/0.621
2evcFC3Methionine aminopeptidase/0.618
2gg8U15Methionine aminopeptidase/0.616
3iu8T03Methionine aminopeptidase 2/0.615
4flkY10Methionine aminopeptidase 1/0.614
2q94A04Methionine aminopeptidase/0.610
3pkaY02Methionine aminopeptidase 2/0.607
2evmFC2Methionine aminopeptidase/0.605
2ggbU17Methionine aminopeptidase/0.605
2q92B23Methionine aminopeptidase/0.603
3pkbY16Methionine aminopeptidase 2/0.598
4iksTFDMethionine aminopeptidase 1/0.598
2g6pHM2Methionine aminopeptidase 1/0.597
2gg0U11Methionine aminopeptidase/0.594
3d27W29Methionine aminopeptidase/0.592
1c23MPHMethionine aminopeptidase/0.585
2p98YE7Methionine aminopeptidase/0.584
4fljY08Methionine aminopeptidase 1/0.578
2q93B21Methionine aminopeptidase/0.574
2p99YE6Methionine aminopeptidase/0.568
2q96A18Methionine aminopeptidase/0.559
2gg3U13Methionine aminopeptidase/0.556
2gg2U12Methionine aminopeptidase/0.553
2gg9U16Methionine aminopeptidase/0.553
3pkcY08Methionine aminopeptidase 2/0.552
1xnzFCDMethionine aminopeptidase/0.551
1odcA8BAcetylcholinesterase3.1.1.70.538
3iu9T07Methionine aminopeptidase 2/0.530
1r5gAO1Methionine aminopeptidase 2/0.528
1votHUPAcetylcholinesterase3.1.1.70.522
1qzyTDEMethionine aminopeptidase 2/0.518
2j3qTFLAcetylcholinesterase3.1.1.70.518
1w6rGNTAcetylcholinesterase3.1.1.70.517
2oazI96Methionine aminopeptidase 2/0.514
1zgbA1EAcetylcholinesterase3.1.1.70.511
2w6cBM4Acetylcholinesterase3.1.1.70.509
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.505
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.505
1r5hAO2Methionine aminopeptidase 2/0.499
1yw9A84Methionine aminopeptidase 2/0.499
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.499
1gaxVAAValine--tRNA ligase6.1.1.90.498
4b7zQ4QAcetylcholinesterase3.1.1.70.498
1e66HUXAcetylcholinesterase3.1.1.70.497
1q84TZ4Acetylcholinesterase3.1.1.70.497
1r58AO5Methionine aminopeptidase 2/0.497
4ey7E20Acetylcholinesterase3.1.1.70.497
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.497
3dvaTPWPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.495
3dvaTPWPyruvate dehydrogenase E1 component subunit beta1.2.4.10.495
4awsFMNNADH:flavin oxidoreductase Sye1/0.495
1h22E10Acetylcholinesterase3.1.1.70.494
2ea4F79Methionine aminopeptidase 2/0.494
2ea2F77Methionine aminopeptidase 2/0.493
2jf0HBPAcetylcholinesterase3.1.1.70.493
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.493
4araC56Acetylcholinesterase3.1.1.70.493
4drn0MCPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.493
1dx6GNTAcetylcholinesterase3.1.1.70.492
1zgcA2EAcetylcholinesterase3.1.1.70.492
2gmuPDGPutative pyridoxamine 5-phosphate-dependent dehydrase/0.492
3h7rNAPAldo-keto reductase family 4 member C8/0.492
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.490
2xuhTZ4Acetylcholinesterase3.1.1.70.490
3uzzTES3-oxo-5-beta-steroid 4-dehydrogenase/0.490
2xupTZ5Acetylcholinesterase3.1.1.70.489
4gg1TZDBenzoylformate decarboxylase4.1.1.70.489
1yw8A75Methionine aminopeptidase 2/0.488
2xuiTZ5Acetylcholinesterase3.1.1.70.488
1jf0CZHObelin/0.487
2cdaNAPGlucose 1-dehydrogenase/0.487
1yw7A41Methionine aminopeptidase 2/0.486
3qpoPFRcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.486
4rxrDCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.486
2xufTZ4Acetylcholinesterase3.1.1.70.485
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.485
2ga2A19Methionine aminopeptidase 2/0.484
1qtiGNTAcetylcholinesterase3.1.1.70.483
3wqmB29Diterpene synthase3.1.7.80.483
1eveE20Acetylcholinesterase3.1.1.70.482
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.482
2xukTZ5Acetylcholinesterase3.1.1.70.482
3zv7NHGAcetylcholinesterase3.1.1.70.482
2xuqTZ4Acetylcholinesterase3.1.1.70.481
4ey6GNTAcetylcholinesterase3.1.1.70.481
2xugTZ4Acetylcholinesterase3.1.1.70.480
2xujTZ5Acetylcholinesterase3.1.1.70.480
4m0f1YKAcetylcholinesterase3.1.1.70.480
4tnzTTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.480
2jl1NAPTriphenylmethane reductase/0.479
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.479
4u163C0Muscarinic acetylcholine receptor M3/0.478
2pb1NFGGlucan 1,3-beta-glucosidase/0.477
4lm4JPZcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.477
2ct8MSPMethionine--tRNA ligase6.1.1.100.476
2xuoTZ4Acetylcholinesterase3.1.1.70.476
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.476
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.476
1e6zNGOChitinase/0.475
2ha6SCKAcetylcholinesterase3.1.1.70.475
2iyaZIOOleandomycin glycosyltransferase/0.475
3uzxAOX3-oxo-5-beta-steroid 4-dehydrogenase/0.475
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.475
1gpnHUBAcetylcholinesterase3.1.1.70.474
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.474
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.474
4arbC57Acetylcholinesterase3.1.1.70.474
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.473
1u65CP0Acetylcholinesterase3.1.1.70.473
2hxzH7JCathepsin S3.4.22.270.473
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.473
4zwpM44Xaa-Pro dipeptidase3.4.13.90.473
1ry0PG2Aldo-keto reductase family 1 member C3/0.472
2wm3NFLNmrA-like family domain-containing protein 1/0.472
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.472
1fkgSB3Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.471
1vkgCRIHistone deacetylase 83.5.1.980.471
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.471
4to6TTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.471
1h60STRPentaerythritol tetranitrate reductase/0.470
3i0oSMISpectinomycin phosphotransferase/0.470
5cxv0HKMuscarinic acetylcholine receptor M1/0.470
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.469
1paxDHQPoly [ADP-ribose] polymerase 12.4.2.300.469
2ckmAA7Acetylcholinesterase3.1.1.70.469
2gyuHI6Acetylcholinesterase3.1.1.70.469
2oz57XYUncharacterized protein/0.469
3qdzPRO_ALA_PRO_ARGProthrombin3.4.21.50.469
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.469
4isg1FYGlucokinase2.7.1.20.469
1qpf858Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.468
2y0jAXCcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.468
4r5wXAVPoly [ADP-ribose] polymerase 12.4.2.300.468
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.467
3gjwGJWPoly [ADP-ribose] polymerase 12.4.2.300.467
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.466
3egkM18Prothrombin3.4.21.50.466
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.466
4dh0MR8Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.466
4kc1WS1Histo-blood group ABO system transferase/0.466
2xi4AFTAcetylcholinesterase3.1.1.70.465
2zevIPEGeranylgeranyl pyrophosphate synthase/0.465
3aivHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic3.2.1.1820.465
1oynROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.464
2vqbNAPPutative flavin-containing monooxygenase/0.464
2xiq5ADMethylmalonyl-CoA mutase, mitochondrial/0.464
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.464
4gm4TZDBenzoylformate decarboxylase4.1.1.70.464
1fkbRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.463
1k4mNADNicotinate-nucleotide adenylyltransferase2.7.7.180.463
1v08NTZ4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic3.2.1.1820.463
1w4lGL8Acetylcholinesterase3.1.1.70.463
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.463
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.463
3lzwNAPFerredoxin--NADP reductase 21.18.1.20.463
3uzzASD3-oxo-5-beta-steroid 4-dehydrogenase/0.463
4bqzGNPEctonucleoside triphosphate diphosphohydrolase 2/0.463
4to0DCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.463
4u140HKMuscarinic acetylcholine receptor M3/0.463
1ut6A8NAcetylcholinesterase3.1.1.70.462
1zisINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.462
2a4xBLMMitomycin-binding protein/0.462
2ovyPFJcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.462
2wcaNP6O-GlcNAcase BT_4395/0.462
2whqHI6Acetylcholinesterase3.1.1.70.462
4br0AU1Ectonucleoside triphosphate diphosphohydrolase 2/0.462
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.462
1ndiCOACarnitine O-acetyltransferase2.3.1.70.461
1q83TZ5Acetylcholinesterase3.1.1.70.461
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.461
2g1n1IGRenin3.4.23.150.461
3f8sPF2Dipeptidyl peptidase 4/0.461
3fsjD7KBenzoylformate decarboxylase4.1.1.70.461
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
3mjrAC2Deoxycytidine kinase2.7.1.740.461
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.461
2e8uIPEGeranylgeranyl pyrophosphate synthase/0.460
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.460
2vq7NAPPutative flavin-containing monooxygenase/0.460
3cotSTR3-oxo-5-beta-steroid 4-dehydrogenase/0.460
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.460
1kruIPTGalactoside O-acetyltransferase2.3.1.180.459
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.459
2cekN8TAcetylcholinesterase3.1.1.70.459
2g1s4IGRenin3.4.23.150.459
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
3m2uCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.459
3mauPLRPutative sphingosine-1-phosphate lyase/0.459
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.459
5a4vQUEGlutathione S-transferase F22.5.1.180.459
1el4CTZObelin/0.458
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.458
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.458
2fznFADBifunctional protein PutA1.5.5.20.458
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.458
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.458
3pm1ETHTH-type transcriptional regulator QacR/0.458
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.458
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.458
4jq4IMNAldo-keto reductase family 1 member C2/0.458
1ro6ROLcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.457
2cbqTH2Neocarzinostatin/0.457
2wcgMT5Glucosylceramidase3.2.1.450.457
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.457
3c1oNAPEugenol synthase/0.457
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
3e6eDCSAlanine racemase/0.457
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.457
3nubUD0UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.457
3t0iSAHPutative methyltransferase/0.457
3zpqXF5Beta-1 adrenergic receptor/0.457
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
4l0oPLPCystathionine gamma-synthase2.5.1.480.457
4mprTPPBenzoylformate decarboxylase4.1.1.70.457
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.457
3d4sTIMBeta-2 adrenergic receptor/0.457
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.456
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.456
3ny8JRZBeta-2 adrenergic receptor/0.456
1rkwPNTHTH-type transcriptional regulator QacR/0.455
2aotSAHHistamine N-methyltransferase2.1.1.80.455
2gywOBIAcetylcholinesterase3.1.1.70.455
3h0bB35Beta-secretase 13.4.23.460.455
3u5ySCGRaucaffricine-O-beta-D-glucosidase3.2.1.1250.455
4bb2STRCorticosteroid-binding globulin/0.455
5iefNBVNeutral alpha-glucosidase AB3.2.1.840.455
2ycxP32Beta-1 adrenergic receptor/0.455
1eirBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.454
1gr1FADFerredoxin--NADP reductase1.18.1.20.454
1qs2NADVip2Ac/0.454
2a3bCFFEndochitinase B13.2.1.140.454
2g1o2IGRenin3.4.23.150.454
2ovvPFHcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.454
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.454
2wzySQXSoluble acetylcholine receptor/0.454
2z4w749Geranylgeranyl pyrophosphate synthase/0.454
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.454
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.454
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.454
3l3mA92Poly [ADP-ribose] polymerase 12.4.2.300.454
4psbGA3Cytokinin-specific binding protein/0.454
1bx1FADFerredoxin--NADP reductase, chloroplastic1.18.1.20.453
1z41FMNNADPH dehydrogenase/0.453
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.453
2z4y252Geranylgeranyl pyrophosphate synthase/0.453
3e4vFMNUncharacterized protein/0.453
3nx2FERFerulic acid decarboxylase/0.453
3zj6VM2Raucaffricine-O-beta-D-glucosidase3.2.1.1250.453
1bl4AP1Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.452
1esmCOAPantothenate kinase2.7.1.330.452
1rp7TZDPyruvate dehydrogenase E1 component1.2.4.10.452
1x1bSAHC-20 methyltransferase/0.452
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.452
2fahGDPPhosphoenolpyruvate carboxykinase [GTP], mitochondrial4.1.1.320.452
3ab1FADFerredoxin--NADP reductase1.18.1.20.452
3af1GDPPantothenate kinase2.7.1.330.452
3rqwACHGamma-aminobutyric-acid receptor subunit beta-1/0.452
3ufl508Beta-secretase 13.4.23.460.452
4gv7MEWPoly [ADP-ribose] polymerase 12.4.2.300.452
4jtqNAPAldo-keto reductase family 1 member C2/0.452
4necSAHPutative SAM-dependent methyltransferase/0.452
4to2DGTDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.452
5cmx0G6Prothrombin3.4.21.50.452
1gj4132Prothrombin3.4.21.50.451
3gxfIFMGlucosylceramidase3.2.1.450.451
3lzzGDPUncharacterized protein/0.451
3v0o4GWHisto-blood group ABO system transferase/0.451
3vyeVYERenin3.4.23.150.451
4lcnGNGCytidine and deoxycytidylate deaminase zinc-binding region/0.451
1b8oIMHPurine nucleoside phosphorylase2.4.2.10.450
1wopFFOAminomethyltransferase/0.450
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.450
3b6pTMPThree-prime repair exonuclease 13.1.11.20.450
3bxoUPPdTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose/0.450
3g1rNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.450
3kkzSAMUncharacterized protein/0.450
3pftFMNFlavin reductase/0.450
3qj0QI3Botulinum neurotoxin type A3.4.24.690.450
3rtnRTNBeta-secretase 13.4.23.460.450
3rupADPBiotin carboxylase6.3.4.140.450
3sxjSAMPutative methyltransferase/0.450
4relKMPGlycosyltransferase/0.450
1a26CNAPoly [ADP-ribose] polymerase 12.4.2.300.449
1p0pBCHCholinesterase3.1.1.80.449
1z6tADPApoptotic protease-activating factor 1/0.449
2rqfJH3Hemolymph juvenile hormone binding protein/0.449
2v19FMNDodecin/0.449
3n87N873-dehydroquinate dehydratase4.2.1.100.449
4bftZVTPantothenate kinase2.7.1.330.449
4eph0RKCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.449
4fpy0V8Sialidase B3.2.1.180.449
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
1opmIYGPeptidyl-glycine alpha-amidating monooxygenase1.14.17.30.448
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.448
2futH1SHeparin and heparin-sulfate lyase/0.448
2gouFMNNADH:flavin oxidoreductase Sye1/0.448
3caqNDP3-oxo-5-beta-steroid 4-dehydrogenase/0.448
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
3juoAJDPhenazine biosynthesis protein A/B/0.448
3mauEXTPutative sphingosine-1-phosphate lyase/0.448
3r43ID8Aldo-keto reductase family 1 member C3/0.448
3r8hZOMAldo-keto reductase family 1 member C3/0.448
3rykTYDdTDP-4-dehydrorhamnose 3,5-epimerase/0.448
4bfsZVSPantothenate kinase2.7.1.330.448
4fam0SZAldo-keto reductase family 1 member C3/0.448
4kxjP34Nucleoprotein/0.448
4nv10FXFormyl transferase/0.448
4x7zZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.448
4xbjIN5Alanine racemase, biosynthetic/0.448
4u150HKMuscarinic acetylcholine receptor M3/0.448
1w6jR71Lanosterol synthase5.4.99.70.447
1yumNCNProbable nicotinate-nucleotide adenylyltransferase2.7.7.180.447
2g263LGRenin3.4.23.150.447
2xjeU5PCytosolic purine 5'-nucleotidase3.1.3.50.447
3cavCI23-oxo-5-beta-steroid 4-dehydrogenase/0.447
3s8pSAMHistone-lysine N-methyltransferase KMT5B2.1.1.430.447
3t8vBTJM1 family aminopeptidase3.4.110.447
3w3lRX8Toll-like receptor 8/0.447
4fhd0TTSpore photoproduct lyase/0.447
4gddNAIUDP-galactopyranose mutase/0.447
5c3rHMUThymine dioxygenase/0.447
3ny9JSZBeta-2 adrenergic receptor/0.447
1e1fPSG4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic3.2.1.1820.446
1gw2FERPeroxidase C1A1.11.1.70.446
1tkbN1TTransketolase 12.2.1.10.446
2v58LZJBiotin carboxylase6.3.4.140.446
2vqzMGTPolymerase basic protein 2/0.446
2xlpFADPutative flavin-containing monooxygenase/0.446
3b8xG4MPutative pyridoxamine 5-phosphate-dependent dehydrase/0.446
3ccc7ACDipeptidyl peptidase 4/0.446
3dr7GPDGDP-perosamine synthase/0.446
3g58988cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.446
3juqAJDPhenazine biosynthesis protein A/B/0.446
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3ntqNADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.446
3v0p4GWHisto-blood group ABO system transferase/0.446
4b66NAPL-ornithine N(5)-monooxygenase/0.446
4f0rMTA5-methylthioadenosine/S-adenosylhomocysteine deaminase/0.446
4g2yNI5cGMP-specific 3',5'-cyclic phosphodiesterase/0.446
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
4iarERM5-hydroxytryptamine receptor 1B/0.446
4mr92BXGamma-aminobutyric acid type B receptor subunit 1/0.446
5ao1DG3Deoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.446
1fklRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.445
1gj5130Prothrombin3.4.21.50.445
1gvrTNLPentaerythritol tetranitrate reductase/0.445
1jwtBLIProthrombin3.4.21.50.445
2aovC2MHistamine N-methyltransferase2.1.1.80.445
2ejzSAHDiphthine synthase/0.445
2g1y5IGRenin3.4.23.150.445
2gs9SAHUncharacterized protein/0.445
3burTES3-oxo-5-beta-steroid 4-dehydrogenase/0.445
3nwlNDPCatalase1.11.1.60.445
3pzcGAPAmino acid--[acyl-carrier-protein] ligase 16.2.1.n20.445
4g8jTHMUridine phosphorylase/0.445
4q0kGA3Phytohormone-binding protein/0.445
4xo7NAPAldo-keto reductase family 1 member C2/0.445
1aquESTEstrogen sulfotransferase, testis isoform2.8.2.40.444
1c9hRAPPeptidyl-prolyl cis-trans isomerase FKBP1B5.2.1.80.444
1i9c5ADGlutamate mutase epsilon subunit/0.444
1k02FMNNADPH dehydrogenase 11.6.99.10.444
1pj6FOLDimethylglycine oxidase1.5.3.100.444
2fkeFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.444
2ipiAKYAclacinomycin-N/aclacinomycin-A oxidase/0.444
2jgbMGTEukaryotic translation initiation factor 4E type 2/0.444
2pucGUNHTH-type transcriptional repressor PurR/0.444
2vf3GVS4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.444
2yp0OVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.444
3fazNOSPurine nucleoside phosphorylase/0.444
3rthRTHBeta-secretase 13.4.23.460.444
3ugrIMNAldo-keto reductase family 1 member C3/0.444
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.444
4fcd0T6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
4m0cFMNFMN-dependent NADH-azoreductase 1/0.444
4qfzTTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.444
4y17LAETranscriptional regulator of ftsQAZ gene cluster/0.444
4yp6NAPNicotinamide-nucleotide adenylyltransferase2.7.7.10.444
5ah5LSSLeucine--tRNA ligase/0.444
1lgtBP3Biphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.443
1o2g696Prothrombin3.4.21.50.443
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.443
2dxdANPNucleoside diphosphate kinase2.7.4.60.443
2wd8VGFPteridine reductase/0.443
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.443
3ix8TX3Transcriptional activator protein LasR/0.443
3k7mFAD6-hydroxy-L-nicotine oxidase/0.443
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.443
3uxvGUNNADPH-dependent 7-cyano-7-deazaguanine reductase/0.443
3v0m5GWHisto-blood group ABO system transferase/0.443
4dbw511Aldo-keto reductase family 1 member C3/0.443
4drm0MCPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.443
4es5MGTPolymerase basic protein 2/0.443
4jt81NRNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.443
4qzuRTLRetinol-binding protein 2/0.443
1akaPLPAspartate aminotransferase, mitochondrial2.6.1.10.442
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.442
1queFADFerredoxin--NADP reductase1.18.1.20.442
1rfuPLPPyridoxal kinase2.7.1.350.442
1waj5GPDNA-directed DNA polymerase/0.442
1x1aSAMC-20 methyltransferase/0.442
2b58COADiamine acetyltransferase 1/0.442
2cmfF11Acetylcholinesterase3.1.1.70.442
2getCOKPantothenate kinase2.7.1.330.442
2nm2NEUDihydroneopterin aldolase/0.442
2yd0BESEndoplasmic reticulum aminopeptidase 13.4.110.442
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3hl0NADMaleylacetate reductase/0.442
3hmvHBTcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.442
3nh8DC2N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming)3.5.1.1140.442
3o57ZG2cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.442
4a7zAY9Aldos-2-ulose dehydratase/0.442
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.442
4e32DWNMethyltransferase/0.442
4uugPXGBranched-chain amino acid aminotransferase, putative/0.442
4wdgA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.442
5c1mCLRMu-type opioid receptor/0.442
1vfsDCSAlanine racemase/0.441
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
2aot2PMHistamine N-methyltransferase2.1.1.80.441
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
2o4gTMPThree-prime repair exonuclease 13.1.11.20.441
2o8h227cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.441
2vt4P32Beta-1 adrenergic receptor/0.441
3akn11DFatty acid-binding protein, intestinal/0.441
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3fktSIIBeta-secretase 13.4.23.460.441
3gx9TXDMorphinone reductase/0.441
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3n71SFGHistone-lysine N-methyltransferase Smyd1/0.441
3sqwANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.441
3uzxAOM3-oxo-5-beta-steroid 4-dehydrogenase/0.441
4b66FADL-ornithine N(5)-monooxygenase/0.441
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.441
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
4n3r2GUTankyrase-12.4.2.300.441
4pneSAHMethyltransferase-like protein/0.441
1ascNPLAspartate aminotransferase2.6.1.10.440
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.440
1fkiSB1Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.440
1hqtNAPAlcohol dehydrogenase [NADP(+)]1.1.1.20.440
1lkdBP6Biphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.440
1s7gNADNAD-dependent protein deacylase 2/0.440
2gqaFMNNADH:flavin oxidoreductase Sye1/0.440
2i65NADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.440
2o6hINI6,7-dimethyl-8-ribityllumazine synthase 12.5.1.780.440
2v57PRLTetR family transcriptional regulator/0.440
3exfTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.440
3exfTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.440
3k8q22APurine nucleoside phosphorylase2.4.2.10.440
3nytULPUDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.440
3o5rFK5Peptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.440
3rsv3RSBeta-secretase 13.4.23.460.440
3v2uATPProtein GAL3/0.440
4dz5NAPAldo-keto reductase family 1 member C3/0.440
4fl0PLPAminotransferase ALD1, chloroplastic2.6.10.440
4js1CTNBeta-galactoside alpha-2,6-sialyltransferase 12.4.99.10.440
4n1gCEIObelin/0.440
5dp2NAPCurF/0.440
5stdUNNScytalone dehydratase4.2.1.940.440
7stdCRPScytalone dehydratase4.2.1.940.440