sc-PDB

List of CHEMBLId :

This value allows a number of roughly comparable measures of half-maximal response concentration/potency/affinity to be compared on a negative logarithmic scale (e.g., an IC50 measurement of 1nM would have a pChEMBL value of 9).

Uniprot Annotation

Name:	Three-prime repair exonuclease 1
ID:	TREX1_MOUSE
AC:	Q91XB0
Organism:	Mus musculus
Reign:	Eukaryota
TaxID:	10090
EC Number:	3.1.11.2

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Chains:

Chain Name:	Percentage of Residues within binding site
C	100 %

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Ligand binding site composition:

B-Factor:	28.547
Number of residues:	28
Including
Standard Amino Acids:	22
Non Standard Amino Acids:	2
Water Molecules:	4
Cofactors:
Metals:	ZN NA

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Cavity properties

Ligandability	Volume (Å3)
0.540	465.750

% Hydrophobic	% Polar
44.20	55.80
According to VolSite

HET Code:	TMP
Formula:	C10H13N2O8P
Molecular weight:	320.193 g/mol
DrugBank ID:	-
Buried Surface Area:	54.1 %
Polar Surface area:	161.1 Å2

Number of
H-Bond Acceptors:	8
H-Bond Donors:	2
Rings:	2
Aromatic rings:	0
Anionic atoms:	2
Cationic atoms:	0
Rule of Five Violation:	0
Rotatable Bonds:	4

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Mass center Coordinates

X	Y	Z
58.8011	-3.89533	-6.05586

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