sc-PDB

List of CHEMBLId :

This value allows a number of roughly comparable measures of half-maximal response concentration/potency/affinity to be compared on a negative logarithmic scale (e.g., an IC50 measurement of 1nM would have a pChEMBL value of 9).

Uniprot Annotation

Name:	Cystathionine gamma-synthase
ID:	METB_HELPY
AC:	P56069
Organism:	Helicobacter pylori
Reign:	Bacteria
TaxID:	85962
EC Number:	2.5.1.48

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Chains:

Chain Name:	Percentage of Residues within binding site
E	7 %
H	93 %

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Ligand binding site composition:

B-Factor:	39.253
Number of residues:	29
Including
Standard Amino Acids:	29
Non Standard Amino Acids:	0
Water Molecules:	0
Cofactors:
Metals:

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Cavity properties

Ligandability	Volume (Å3)
0.073	705.375

% Hydrophobic	% Polar
39.71	60.29
According to VolSite

HET Code:	PLP
Formula:	C8H8NO6P
Molecular weight:	245.126 g/mol
DrugBank ID:	DB00114
Buried Surface Area:	68.25 %
Polar Surface area:	132.42 Å2

Number of
H-Bond Acceptors:	7
H-Bond Donors:	1
Rings:	1
Aromatic rings:	1
Anionic atoms:	2
Cationic atoms:	0
Rule of Five Violation:	0
Rotatable Bonds:	4

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Mass center Coordinates

X	Y	Z
53.8862	-1.481	-30.8351

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