sc-PDB

List of CHEMBLId :

This value allows a number of roughly comparable measures of half-maximal response concentration/potency/affinity to be compared on a negative logarithmic scale (e.g., an IC50 measurement of 1nM would have a pChEMBL value of 9).

Uniprot Annotation

Name:	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
ID:	PK3CG_PIG
AC:	O02697
Organism:	Sus scrofa
Reign:	Eukaryota
TaxID:	9823
EC Number:	2.7.1.153

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Chains:

Chain Name:	Percentage of Residues within binding site
A	100 %

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Ligand binding site composition:

B-Factor:	57.052
Number of residues:	28
Including
Standard Amino Acids:	27
Non Standard Amino Acids:	0
Water Molecules:	1
Cofactors:
Metals:

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Cavity properties

Ligandability	Volume (Å3)
1.032	624.375

% Hydrophobic	% Polar
56.22	43.78
According to VolSite

HET Code:	LY2
Formula:	C19H17NO3
Molecular weight:	307.343 g/mol
DrugBank ID:	DB02656
Buried Surface Area:	61.43 %
Polar Surface area:	38.77 Å2

Number of
H-Bond Acceptors:	4
H-Bond Donors:	0
Rings:	4
Aromatic rings:	2
Anionic atoms:	0
Cationic atoms:	0
Rule of Five Violation:	0
Rotatable Bonds:	2

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Mass center Coordinates

X	Y	Z
20.9517	62.3286	21.4085

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