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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4ixgIXGDihydrofolate reductase1.5.1.3

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4ixgIXGDihydrofolate reductase1.5.1.31.000
4ixfIXFDihydrofolate reductase1.5.1.30.723
1dajMOTDihydrofolate reductase1.5.1.30.671
2cd2FOLDihydrofolate reductase1.5.1.30.667
2fziDH3Dihydrofolate reductase1.5.1.30.621
3eej53RUncharacterized protein/0.611
1j3iWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.607
2zzaFOLDihydrofolate reductase/0.605
3dgaRJ1Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.604
1e26GPBDihydrofolate reductase1.5.1.30.603
1cd2FOLDihydrofolate reductase1.5.1.30.602
3eem53VUncharacterized protein/0.602
3qly55VUncharacterized protein/0.602
3td8D2RDihydrofolate reductase1.5.1.30.600
1hfqMOTDihydrofolate reductase1.5.1.30.599
3cseN22Uncharacterized protein/0.596
3invC50Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.593
4h9814QUncharacterized protein/0.592
2fzjDH3Dihydrofolate reductase1.5.1.30.590
4g8zTOPDihydrofolate reductase1.5.1.30.590
3eek53SUncharacterized protein/0.589
1dg7WRBDihydrofolate reductase1.5.1.30.588
3qlxQLRUncharacterized protein/0.588
1j3kWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.587
2w3wVG9Dihydrofolate reductase/0.586
3eel53TUncharacterized protein/0.585
3qlrQLRDihydrofolate reductase1.5.1.30.584
3qlzQLZUncharacterized protein/0.579
4nx7FOLDihydrofolate reductase1.5.1.30.579
3kjsDQ1Bifunctional dihydrofolate reductase-thymidylate synthase/0.573
1klkPMDDihydrofolate reductase1.5.1.30.572
1ly3COGDihydrofolate reductase1.5.1.30.571
4dphP65Bifunctional dihydrofolate reductase-thymidylate synthase/0.569
3um61CYBifunctional dihydrofolate reductase-thymidylate synthase/0.566
1aoeGW3Dihydrofolate reductase1.5.1.30.565
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.565
4m6l21VDihydrofolate reductase1.5.1.30.563
3cd2MTXDihydrofolate reductase1.5.1.30.561
3ia4MTXDihydrofolate reductase/0.561
3tq9MTXDihydrofolate reductase/0.560
3qg2CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.559
1rx3MTXDihydrofolate reductase1.5.1.30.557
3srrQ20Dihydrofolate reductase1.5.1.30.557
4ky404JBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.557
1kmsLIHDihydrofolate reductase1.5.1.30.556
3dfrMTXDihydrofolate reductase1.5.1.30.556
3um5CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.556
1vj3TABDihydrofolate reductase1.5.1.30.554
3qls55VDihydrofolate reductase1.5.1.30.554
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.553
4kjjFOLDihydrofolate reductase1.5.1.30.552
1hfpMOTDihydrofolate reductase1.5.1.30.551
3frfXCFDihydrofolate reductase1.5.1.30.551
4h9506UDihydrofolate reductase1.5.1.30.550
2w3vTOPDihydrofolate reductase/0.549
3frdDHFDihydrofolate reductase1.5.1.30.549
1dg5TOPDihydrofolate reductase1.5.1.30.546
3iro2CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.545
3ntz3TZDihydrofolate reductase1.5.1.30.545
1ia1TQ3Dihydrofolate reductase1.5.1.30.544
1qzfFOLBifunctional dihydrofolate reductase-thymidylate synthase/0.544
3fy9XCFDihydrofolate reductase1.5.1.30.544
3qfxCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.544
4h9614QDihydrofolate reductase1.5.1.30.543
3jw5TOPDihydrofolate reductase/0.541
4m2xTMQDihydrofolate reductase1.5.1.30.541
4xe606UDihydrofolate reductase1.5.1.30.541
2fzhDH1Dihydrofolate reductase1.5.1.30.539
4h9753SDihydrofolate reductase1.5.1.30.539
4x5gFOLDihydrofolate reductase1.5.1.30.538
4nx6FOLDihydrofolate reductase1.5.1.30.536
1m78CLZDihydrofolate reductase1.5.1.30.535
3srwQ27Dihydrofolate reductase1.5.1.30.535
1df7MTXDihydrofolate reductase1.5.1.30.534
3dauMTXDihydrofolate reductase1.5.1.30.534
3tqbFOLDihydrofolate reductase/0.534
7dfrFOLDihydrofolate reductase1.5.1.30.534
3l3rOAGDihydrofolate reductase1.5.1.30.533
3datMTXDihydrofolate reductase/0.532
3freTOPDihydrofolate reductase1.5.1.30.531
3srqQ19Dihydrofolate reductase1.5.1.30.530
1j3jCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.527
3jsuKA5Bifunctional dihydrofolate reductase-thymidylate synthase/0.527
3hz137DHeat shock protein HSP 90-alpha/0.526
3ix9MTXDihydrofolate reductase1.5.1.30.526
3qlwN22Dihydrofolate reductase1.5.1.30.526
2blbCP7Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.524
1s3yTQTDihydrofolate reductase1.5.1.30.521
3jwm5WBDihydrofolate reductase/0.521
1rx2FOLDihydrofolate reductase1.5.1.30.520
3k47D09Dihydrofolate reductase1.5.1.30.519
3sa16DRDihydrofolate reductase/0.519
4kd79DRDihydrofolate reductase1.5.1.30.519
1kmvLIIDihydrofolate reductase1.5.1.30.518
4ixeIXEDihydrofolate reductase1.5.1.30.518
4kfj1R0Dihydrofolate reductase1.5.1.30.518
3ql3FOLDihydrofolate reductase1.5.1.30.516
1m7aMQUDihydrofolate reductase1.5.1.30.515
4eilFOLBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.515
1ohjCOPDihydrofolate reductase1.5.1.30.514
1rx8FOLDihydrofolate reductase1.5.1.30.514
3mnrSD1Heat shock protein HSP 90-alpha/0.514
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.514
4kak06UDihydrofolate reductase1.5.1.30.514
3fywXCFDihydrofolate reductase1.5.1.30.513
3fyvXCFDihydrofolate reductase1.5.1.30.512
1dyrTOPDihydrofolate reductase1.5.1.30.511
2w9gTOPDihydrofolate reductase1.5.1.30.511
3jwcEKBDihydrofolate reductase/0.511
3fy8XCFDihydrofolate reductase1.5.1.30.510
3qgtCP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.509
3sgy06WDihydrofolate reductase1.5.1.30.509
4fgh0U6Dihydrofolate reductase1.5.1.30.509
3ghwGHWDihydrofolate reductase1.5.1.30.508
1s3uTQDDihydrofolate reductase1.5.1.30.507
3nxvD2FDihydrofolate reductase1.5.1.30.507
3sa27DRDihydrofolate reductase/0.507
4m7vRARDihydrofolate reductase/0.507
3clbTMQBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.506
3sai9DRDihydrofolate reductase/0.506
4hni16WCasein kinase I isoform epsilon2.7.11.10.506
1bozPRDDihydrofolate reductase1.5.1.30.505
3sh25DRDihydrofolate reductase1.5.1.30.505
1ddsMTXDihydrofolate reductase1.5.1.30.504
3d80Q22Dihydrofolate reductase1.5.1.30.503
3oafOAGDihydrofolate reductase1.5.1.30.503
4p66MTXDihydrofolate reductase/0.503
3dg8RJ6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.502
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.502
4dp3MMVBifunctional dihydrofolate reductase-thymidylate synthase/0.502
4o701QKBromodomain-containing protein 4/0.502
3gyf51PDihydrofolate reductase1.5.1.30.501
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.501
2ykcYKCHeat shock protein HSP 90-alpha/0.500
3drcMTXDihydrofolate reductase1.5.1.30.500
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.499
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.499
1hfrMOTDihydrofolate reductase1.5.1.30.498
1u72MTXDihydrofolate reductase1.5.1.30.498
3srsM23Dihydrofolate reductase1.5.1.30.498
4iui1GQEstrogen receptor/0.498
4kebFOLDihydrofolate reductase1.5.1.30.498
1pd9CO4Dihydrofolate reductase1.5.1.30.497
1rb3MTXDihydrofolate reductase1.5.1.30.497
1uy8PU5Heat shock protein HSP 90-alpha/0.497
2w3mFOLDihydrofolate reductase1.5.1.30.497
1sejF89Bifunctional dihydrofolate reductase-thymidylate synthase/0.496
2g2hP16Tyrosine-protein kinase ABL12.7.10.20.496
3eigMTXDihydrofolate reductase1.5.1.30.496
3m08RARDihydrofolate reductase1.5.1.30.496
1dreMTXDihydrofolate reductase1.5.1.30.495
4hy6FJ1Heat shock protein HSP 90-alpha/0.495
4kbn25UDihydrofolate reductase1.5.1.30.495
2h55DZ8Heat shock protein HSP 90-alpha/0.494
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.494
1pd8CO4Dihydrofolate reductase1.5.1.30.493
3lu8IQXSerum albumin/0.493
3sqyQ11Dihydrofolate reductase1.5.1.30.493
4geb0LDKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.493
1mvsDTMDihydrofolate reductase1.5.1.30.492
1ohkCOPDihydrofolate reductase1.5.1.30.492
1uykPUXHeat shock protein HSP 90-alpha/0.492
2blcCP7Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.492
4fgg0U5Dihydrofolate reductase1.5.1.30.492
4qa0SHHHistone deacetylase 83.5.1.980.492
2ykjYKJHeat shock protein HSP 90-alpha/0.491
1jolFFODihydrofolate reductase1.5.1.30.490
1rg7MTXDihydrofolate reductase1.5.1.30.490
2zb45OPProstaglandin reductase 21.3.1.480.490
3gi2GHWDihydrofolate reductase1.5.1.30.490
3k4551PDihydrofolate reductase1.5.1.30.490
3nr4PYVAbscisic acid receptor PYL2/0.490
3tq8TOPDihydrofolate reductase/0.490
4iv21GREstrogen receptor/0.489
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.489
1zdwFLVPrenyltransferase/0.488
3fl8RARDihydrofolate reductase/0.488
3kpzZNEVitamin D3 receptor/0.488
4bb3KKAIsopenicillin N synthase1.21.3.10.488
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.488
2x9dITCTetracycline repressor protein class D/0.487
3lnbCOAN-acetyltransferase family protein/0.487
3vt8YI3Vitamin D3 receptor/0.487
4fqsLYAThymidylate synthase ThyA/0.487
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.487
4x5fFOLDihydrofolate reductase1.5.1.30.487
1diuBDMDihydrofolate reductase1.5.1.30.486
1ly4COQDihydrofolate reductase1.5.1.30.486
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.486
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.486
2hm9TRRDihydrofolate reductase1.5.1.30.486
3fraI2HDihydrofolate reductase1.5.1.30.486
3ghvGHCDihydrofolate reductase1.5.1.30.486
3i8aN22Dihydrofolate reductase1.5.1.30.486
4cd2FOLDihydrofolate reductase1.5.1.30.486
4elf35IDihydrofolate reductase/0.486
4gg70J8Hepatocyte growth factor receptor2.7.10.10.486
1e7qNAPGDP-L-fucose synthase/0.485
4egnTWOCytochrome P450/0.485
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.485
4v12POGMaoC like domain protein/0.485
1ia2TQ4Dihydrofolate reductase1.5.1.30.484
1s3vTQDDihydrofolate reductase1.5.1.30.484
1uyePU9Heat shock protein HSP 90-alpha/0.484
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.484
2nq8ZIDEnoyl-ACP reductase/0.484
2vn0TDZCytochrome P450 2C8/0.484
2ykbYKBHeat shock protein HSP 90-alpha/0.484
3s7a684Dihydrofolate reductase1.5.1.30.484
4ele31IDihydrofolate reductase/0.484
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.484
4qa1B3NHistone deacetylase 83.5.1.980.484
4wa9AXITyrosine-protein kinase ABL12.7.10.20.484
5dc5B3NHistone deacetylase 83.5.1.980.484
1bwsNDPGDP-L-fucose synthase/0.483
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.483
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.483
3dd125DGlycogen phosphorylase, liver form2.4.1.10.483
3um81CYBifunctional dihydrofolate reductase-thymidylate synthase/0.483
4elb34SDihydrofolate reductase/0.483
4qa2SHHHistone deacetylase 83.5.1.980.483
1g6cTZPThiamine-phosphate synthase/0.482
1zzlTZYMitogen-activated protein kinase 14/0.482
2jedLG8Protein kinase C theta type2.7.11.130.482
3a1l2CCCytochrome P450/0.482
3hz5Z64Heat shock protein HSP 90-alpha/0.482
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.482
3uvvREARetinoic acid receptor RXR-alpha/0.482
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.482
4j7xSASSepiapterin reductase1.1.1.1530.482
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.482
4nh82LCHeat shock protein HSP 90-alpha/0.482
5iua6DXAdenosine receptor A2a/0.482
1bk0ACVIsopenicillin N synthase1.21.3.10.481
1blzACVIsopenicillin N synthase1.21.3.10.481
1m79MQ1Dihydrofolate reductase1.5.1.30.481
1rx6DDFDihydrofolate reductase1.5.1.30.481
2ph5NADHomospermidine synthase/0.481
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.481
3nu03TUDihydrofolate reductase1.5.1.30.481
4at3LTIBDNF/NT-3 growth factors receptor2.7.10.10.481
4elg52JDihydrofolate reductase/0.481
4jq7KJQEpidermal growth factor receptor2.7.10.10.481
1db1VDXVitamin D3 receptor/0.480
1disBDMDihydrofolate reductase1.5.1.30.480
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.480
3iw4LW4Protein kinase C alpha type2.7.11.130.480
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.480
1lhwESMSex hormone-binding globulin/0.479
2blaCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.479
2ftoCB3Thymidylate synthase/0.479
3el8PD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.479
3q5kD1UHeat shock protein 83-1/0.479
3vt9YI4Vitamin D3 receptor/0.479
3zkyWT4Isopenicillin N synthase1.21.3.10.479
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.479
4ryvZEAProtein LlR18A/0.479
1jxzBCA4-chlorobenzoyl coenzyme A dehalogenase3.8.1.70.478
1uy6PU3Heat shock protein HSP 90-alpha/0.478
1w1rZEACytokinin dehydrogenase 11.5.99.120.478
2fai459Estrogen receptor/0.478
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.478
3bgxMEFThymidylate synthase/0.478
3gmd2M3Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.478
3och2MXDihydrofolate reductase1.5.1.30.478
4a9mP9MBromodomain-containing protein 2/0.478
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.478
4j6bPLOCytochrome P450 monooxygenase/0.478
1kt3RTLRetinol-binding protein 4/0.477
1q5dEPBEpothilone C/D epoxidase1.140.477
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.477
3bgrT27Gag-Pol polyprotein2.7.7.490.477
3gc9B45Mitogen-activated protein kinase 112.7.11.240.477
3rg9WRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.477
4j7uYTZSepiapterin reductase1.1.1.1530.477
4l9kEHFSerum albumin/0.477
4m6kFOLDihydrofolate reductase1.5.1.30.477
5jtbZMAAdenosine receptor A2a/0.477
1tsdF89Thymidylate synthase/0.476
1uydPU8Heat shock protein HSP 90-alpha/0.476
2bbqPFGThymidylate synthase/0.476
2hamC33Vitamin D3 receptor/0.476
2z3uCRRCytochrome P450/0.476
3jw3TOPDihydrofolate reductase/0.476
3w5p4OAVitamin D3 receptor/0.476
4ix6ADPUncharacterized protein/0.476
4jq8KJ8Epidermal growth factor receptor2.7.10.10.476
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.476
1jtqLY3Thymidylate synthase/0.475
1u70MTXDihydrofolate reductase1.5.1.30.475
1uy9PU6Heat shock protein HSP 90-alpha/0.475
1zg32HIIsoflavone 4'-O-methyltransferase/0.475
2hb8MVDVitamin D3 receptor/0.475
2pwsIBPBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.475
3sr5Q12Dihydrofolate reductase1.5.1.30.475
4a7cE46Serine/threonine-protein kinase pim-12.7.11.10.475
5cccDDFDihydrofolate reductase1.5.1.30.475
1e7aPFLSerum albumin/0.474
1kl2FONSerine hydroxymethyltransferase/0.474
2chw039Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.474
3hu2AGSTransitional endoplasmic reticulum ATPase3.6.4.60.474
3sruQ26Dihydrofolate reductase1.5.1.30.474
3tdaPN0Cytochrome P450 2D6/0.474
4l8u9AZSerum albumin/0.474
4uyf73BBromodomain-containing protein 2/0.474
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.473
3hu1AGSTransitional endoplasmic reticulum ATPase3.6.4.60.473
3kk6CELProstaglandin G/H synthase 11.14.99.10.473
3qtsX46Cyclin-dependent kinase 22.7.11.220.473
3qyoQ24Dihydrofolate reductase1.5.1.30.473
3vt7VDXVitamin D3 receptor/0.473
4elh53IDihydrofolate reductase/0.473
4nb6444Nuclear receptor ROR-gamma/0.473
4twpAXITyrosine-protein kinase ABL12.7.10.20.473
5g53NECAdenosine receptor A2a/0.473
5uviZMAAdenosine receptor A2a/0.473
1bsvNDPGDP-L-fucose synthase/0.472
1ddrMTXDihydrofolate reductase1.5.1.30.472
1re7FOLDihydrofolate reductase1.5.1.30.472
1s6qTPBGag-Pol polyprotein2.7.7.490.472
2q7gCCLPyrrolysine--tRNA ligase/0.472
2x7hPFNProstaglandin reductase 310.472
3gwfFADCyclohexanone monooxygenase/0.472
3ielU5PRibonuclease TTHA02523.10.472
3nxyD2HDihydrofolate reductase1.5.1.30.472
3v94WYQPhosphodiesterase/0.472
4cax646Glycylpeptide N-tetradecanoyltransferase2.3.1.970.472
4rupH97Vitamin D3 receptor A/0.472
1fmjRTLRetinol dehydratase/0.471
1lcoPPYCytochrome b2, mitochondrial1.1.2.30.471
2ban357Gag-Pol polyprotein2.7.7.490.471
2wo7ASVIsopenicillin N synthase1.21.3.10.471
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.471
3w5rLOAVitamin D3 receptor/0.471
4ivy1GTEstrogen receptor/0.471
5k2aZMAAdenosine receptor A2a/0.471
1dhfFOLDihydrofolate reductase1.5.1.30.470
1fmlRTLRetinol dehydratase/0.470
1fvpFMANon-fluorescent flavoprotein/0.470
1gwrESTEstrogen receptor/0.470
1ot7CHCBile acid receptor/0.470
1tduCB3Thymidylate synthase/0.470
2bxmIMNSerum albumin/0.470
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.470
2w03ADNAcsD/0.470
2wugHPK4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.470
2y6fM9FIsopenicillin N synthase1.21.3.10.470
4awo99BHeat shock protein HSP 90-alpha/0.470
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.470
4i8vBHFCytochrome P450 1A11.14.14.10.470
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.469
1ek2CDUBifunctional epoxide hydrolase 2/0.469
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.469
1kzjCB3Thymidylate synthase/0.469
1pkfEPDEpothilone C/D epoxidase1.140.469
1uy7PU4Heat shock protein HSP 90-alpha/0.469
1zgaHMKIsoflavone 4'-O-methyltransferase/0.469
2be2R22Gag-Pol polyprotein2.7.7.490.469
2yk2YJXHeat shock protein HSP 90-alpha/0.469
3a783EVVitamin D3 receptor/0.469
3vrwYS5Vitamin D3 receptor/0.469
4az3S35Lysosomal protective protein3.4.16.50.469
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.469
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.469
4elb34RDihydrofolate reductase/0.469
4enhFVXCholesterol 24-hydroxylase/0.469
4fhbFOLDihydrofolate reductase1.5.1.30.469
4ia7BIVVitamin D3 receptor A/0.469
4j6cSTRCytochrome P450 monooxygenase/0.469
4knzCB3Thymidylate synthase/0.469
1dnaCB3Thymidylate synthase/0.468
1g4sTPSThiamine-phosphate synthase/0.468
1ie9VDXVitamin D3 receptor/0.468
1sr7MOFProgesterone receptor/0.468
1uycPU7Heat shock protein HSP 90-alpha/0.468
1zw9H64ATP-dependent molecular chaperone HSP82/0.468
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.468
2hcdBIVVitamin D3 receptor A/0.468
2vbdV10Isopenicillin N synthase1.21.3.10.468
2yeiXQIHeat shock protein HSP 90-alpha/0.468
3ar4TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.468
3inwJZBHeat shock protein HSP 90-alpha/0.468
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.468
3qdd94MHeat shock protein HSP 90-alpha/0.468
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.468
4dgo0JWCasein kinase II subunit alpha2.7.11.10.468
4g2yNI5cGMP-specific 3',5'-cyclic phosphodiesterase/0.468
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.468
4zasTYDCalS13/0.468
5ikqJMSProstaglandin G/H synthase 21.14.99.10.468
1s19MC9Vitamin D3 receptor/0.467
1zprCB3Thymidylate synthase/0.467
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.467
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.467
3fsuC2F5,10-methylenetetrahydrofolate reductase1.5.1.200.467
3gc8B45Mitogen-activated protein kinase 112.7.11.240.467
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.467
3meeT27Gag-Pol polyprotein2.7.7.490.467
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.467
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.467
4c9pCAMCytochrome P450/0.467
4feu537Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.467
5k2cZMAAdenosine receptor A2a/0.467
1a27ESTEstradiol 17-beta-dehydrogenase 11.1.1.620.466
1rt5UC2Gag-Pol polyprotein2.7.7.490.466
1uyhPU0Heat shock protein HSP 90-alpha/0.466
3dolGWIPol protein/0.466
3h3r14HCollagen type IV alpha-3-binding protein/0.466
3nxtD2EDihydrofolate reductase1.5.1.30.466
3pre3REPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
3uwlFOZThymidylate synthase/0.466
4g1qT27Gag-Pol polyprotein2.7.7.490.466
4gevCB3Thymidylate synthase/0.466
4gkh0J9Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.466
4iw8KN3Estrogen receptor/0.466
4p6xHCYGlucocorticoid receptor/0.466
1draMTXDihydrofolate reductase1.5.1.30.465
1m52P17Tyrosine-protein kinase ABL12.7.10.20.465
1oc1ASVIsopenicillin N synthase1.21.3.10.465
1rc4DDFDihydrofolate reductase1.5.1.30.465
1rt4UC1Gag-Pol polyprotein2.7.7.490.465
1uzwCDHIsopenicillin N synthase1.21.3.10.465
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.465
2i0ePDSProtein kinase C beta type2.7.11.130.465
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.465
2xlsFADPutative flavin-containing monooxygenase/0.465
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.465
3dcv55ESerine/threonine-protein kinase pim-12.7.11.10.465
3e5aVX6Aurora kinase A2.7.11.10.465
3fznD7KBenzoylformate decarboxylase4.1.1.70.465
3hz142CHeat shock protein HSP 90-alpha/0.465
3ibqATPPyridoxal kinase/0.465
3mqe416Prostaglandin G/H synthase 21.14.99.10.465
3nxrD2DDihydrofolate reductase1.5.1.30.465
3pe2E1BCasein kinase II subunit alpha2.7.11.10.465
3t3q9PLCytochrome P450 2A61.14.130.465
4b1fKRHGlutamate racemase/0.465
4jlj1NMDeoxycytidine kinase2.7.1.740.465
4lsjLSJGlucocorticoid receptor/0.465
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.465
5cvhADPCasein kinase II subunit alpha2.7.11.10.465
1hb3SCVIsopenicillin N synthase1.21.3.10.464
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.464
1n4hREANuclear receptor ROR-beta/0.464
1nceCB3Thymidylate synthase/0.464
1qiqACCIsopenicillin N synthase1.21.3.10.464
1zeoC01Peroxisome proliferator-activated receptor gamma/0.464
2fwzH71Heat shock protein HSP 90-alpha/0.464
2giuFBREstrogen receptor beta/0.464
2jj2ANPATP synthase subunit beta, mitochondrial3.6.3.140.464
2yncYNCGlycylpeptide N-tetradecanoyltransferase/0.464
3g4kROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.464
3is9AC7Gag-Pol polyprotein2.7.7.490.464
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.464
3new3NEMitogen-activated protein kinase 14/0.464
3nga3NGCasein kinase II subunit alpha2.7.11.10.464
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.464
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.464
4bbhNHWGlycylpeptide N-tetradecanoyltransferase/0.464
4eiyZMAAdenosine receptor A2a/0.464
4oal245Cytokinin dehydrogenase 4/0.464
5d7q4I5NAD-dependent protein deacetylase sirtuin-23.5.10.464
5iu4ZMAAdenosine receptor A2a/0.464
1synF89Thymidylate synthase/0.463
1t1rIMB1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.463
1w78PD8Dihydrofolate synthase/folylpolyglutamate synthase6.3.2.120.463
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.463
2ewaSB2Mitogen-activated protein kinase 14/0.463
2ji9ADPOxalyl-CoA decarboxylase4.1.1.80.463
2vbpVB1Isopenicillin N synthase1.21.3.10.463
2ykeYKEHeat shock protein HSP 90-alpha/0.463
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.463
2zb8IMNProstaglandin reductase 21.3.1.480.463
2zbaZBATrichothecene 3-O-acetyltransferase/0.463
2zd1T27Gag-Pol polyprotein2.7.7.490.463
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.463
3koo24DBifunctional epoxide hydrolase 23.3.2.100.463
3o6o94MHeat shock protein 83/0.463
3vjhJ35Peroxisome proliferator-activated receptor gamma/0.463
3vt5YI2Vitamin D3 receptor/0.463
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
4ddrMMVDihydrofolate reductase1.5.1.30.463
4dquNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.463
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.463
4mfb29TGag-Pol polyprotein2.7.7.490.463
4oew5IOcGMP-specific 3',5'-cyclic phosphodiesterase/0.463
4tuvCPZCytochrome P450 1191.140.463
4yswNAIXanthine dehydrogenase/oxidase/0.463
5hwoHMGHydroxymethylglutaryl-CoA synthase/0.463
3reyXACAdenosine receptor A2a/0.463
3emlZMAAdenosine receptor A2a/0.463
1fxsNAPGDP-L-fucose synthase/0.462
1s9qOHTEstrogen-related receptor gamma/0.462
1xoqROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.462
2a8sGTPU8 snoRNA-decapping enzyme/0.462
2ehlSAHDiphthine synthase/0.462
2iviACWIsopenicillin N synthase1.21.3.10.462
2m56CAMCamphor 5-monooxygenase1.14.15.10.462
2npnSAMPutative cobalamin synthesis related protein/0.462
2qg2A91Heat shock protein HSP 90-alpha/0.462
2y98MIVMycinamicin IV hydroxylase/epoxidase/0.462
2z97CAMCamphor 5-monooxygenase1.14.15.10.462
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.462
3hu3AGSTransitional endoplasmic reticulum ATPase3.6.4.60.462
3hxeBD8Geranylgeranyl transferase type-2 subunit beta2.5.1.600.462
3negPYVAbscisic acid receptor PYL1/0.462
3pm0BHFCytochrome P450 1B1/0.462
3r336MEDihydrofolate reductase1.5.1.30.462
3vtbTKAVitamin D3 receptor/0.462
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.462
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
4eh9IRGMitogen-activated protein kinase 14/0.462
4g1z0VPVitamin D3 receptor A/0.462
4pxmESTEstrogen receptor/0.462
4z1fH71Heat shock protein 75 kDa, mitochondrial/0.462
1jomFFODihydrofolate reductase1.5.1.30.461
1kceCB3Thymidylate synthase/0.461
1tl3H20Gag-Pol polyprotein2.7.7.490.461
1x7b041Estrogen receptor beta/0.461
1x7e244Estrogen receptor/0.461
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.461
2bilBI1Serine/threonine-protein kinase pim-12.7.11.10.461
2fm0M98cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.461
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.461
2zl9VDAVitamin D3 receptor/0.461
3g72A6TRenin3.4.23.150.461
3l034OHEstrogen receptor/0.461
3lanKBTGag-Pol polyprotein2.7.7.490.461
3oom507Activin receptor type-12.7.11.300.461
3u8hBHPPhospholipase A2, membrane associated/0.461
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4f1sF1SPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4fhh0U3Vitamin D3 receptor A/0.461
4ho4THMGlucose-1-phosphate thymidylyltransferase/0.461
1djqFMNTrimethylamine dehydrogenase1.5.8.20.460
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.460
1qjfACSIsopenicillin N synthase1.21.3.10.460
1rt1MKCGag-Pol polyprotein2.7.7.490.460
1rx5DDFDihydrofolate reductase1.5.1.30.460
1t87CAMCamphor 5-monooxygenase1.14.15.10.460
1uyfPU1Heat shock protein HSP 90-alpha/0.460
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.460
2ow3BIMGlycogen synthase kinase-3 beta2.7.11.260.460
2vagV25Dual specificity protein kinase CLK12.7.12.10.460
2vg7NNIGag-Pol polyprotein2.7.7.490.460
3adaNADSubunit alpha of sarocosine oxidase/0.460
3ar7TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.460
3czr3CZCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.460
3drrR8EGag-Pol polyprotein2.7.7.490.460
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.460
3fl9TOPDihydrofolate reductase/0.460
3g0fB49Mast/stem cell growth factor receptor Kit2.7.10.10.460
3h3sH15Collagen type IV alpha-3-binding protein/0.460
3jziJZLBiotin carboxylase6.3.4.140.460
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
3nhrRZWRibosyldihydronicotinamide dehydrogenase [quinone]/0.460
3vruYS3Vitamin D3 receptor/0.460
3vt65YIVitamin D3 receptor/0.460
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.460
4j24ESTEstrogen receptor beta/0.460
4jnm1LJNicotinamide phosphoribosyltransferase2.4.2.120.460
4mr61K0Bromodomain-containing protein 2/0.460
4myq19TcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.460
4o95245Cytokinin dehydrogenase 4/0.460
4okx198Androgen receptor/0.460
1c1bGCAGag-Pol polyprotein2.7.7.490.459
1dkfBMSRetinoic acid receptor alpha/0.459
1fxoTMPGlucose-1-phosphate thymidylyltransferase/0.459
1mc5AHEAlcohol dehydrogenase class-31.1.1.10.459
1pxxDIFProstaglandin G/H synthase 21.14.99.10.459
1rk3VDXVitamin D3 receptor/0.459
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.459
1yinCM3Estrogen receptor/0.459
2dhfDZFDihydrofolate reductase1.5.1.30.459
2hl0A3SThreonine--tRNA ligase6.1.1.30.459
2jj3JJ3Estrogen receptor beta/0.459
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.459
2ocfESTEstrogen receptor/0.459
2q70DC8Estrogen receptor/0.459
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.459
2yjxYJXHeat shock protein HSP 90-alpha/0.459
3c6uM22Gag-Pol polyprotein2.7.7.490.459
3k9uACOSpermidine N(1)-acetyltransferase/0.459
3lfeZ84Mitogen-activated protein kinase 14/0.459
3o73O73Ribosyldihydronicotinamide dehydrogenase [quinone]/0.459
3p3zP3ZPutative cytochrome P450/0.459
3qm4PN0Cytochrome P450 2D6/0.459
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.459
3v49PK0Androgen receptor/0.459
3w5tLHPVitamin D3 receptor/0.459
3wd9QPCcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.459
3wsbRWZFarnesyltransferase, putative/0.459
3zoiM2WIsopenicillin N synthase1.21.3.10.459
4eos1ROCyclin-dependent kinase 22.7.11.220.459
4ig3T27Gag-Pol polyprotein2.7.7.490.459
4iteTEYVitamin D3 receptor/0.459
4j6dTESCytochrome P450 monooxygenase/0.459
4la0198Serum albumin/0.459
4ly91YYGlucokinase regulatory protein/0.459
4mv1ADPBiotin carboxylase6.3.4.140.459
4r21STRCytochrome P450 family 17 polypeptide 2/0.459
5aluHD2Bifunctional epoxide hydrolase 23.1.3.760.459
1bxdANPOsmolarity sensor protein EnvZ2.7.13.30.458
1cdeGARPhosphoribosylglycinamide formyltransferase/0.458
1cjkFOKAdenylate cyclase type 2/0.458
1cjkFOKAdenylate cyclase type 5/0.458
1dyjDDFDihydrofolate reductase1.5.1.30.458
1jtuLYBThymidylate synthase/0.458
1lsoNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.458
1o5rFR9Adenosine deaminase3.5.4.40.458
1olmVTQSEC14-like protein 2/0.458
1tl1H18Gag-Pol polyprotein2.7.7.490.458
1w06W05Isopenicillin N synthase1.21.3.10.458
2bu9HFVIsopenicillin N synthase1.21.3.10.458
2c3u2TPPyruvate synthase/0.458
2hasC3OVitamin D3 receptor/0.458
2hb7O1CVitamin D3 receptor/0.458
2zjwREFCasein kinase II subunit alpha2.7.11.10.458
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.458
3clrFADElectron transfer flavoprotein subunit alpha/0.458
3cv9VDXVitamin D3 dihydroxylase/0.458
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.458
4eilCB3Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.458
4h6pFMNChromate reductase/0.458
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.458
4i0t1B6Tyrosine-protein kinase SYK2.7.10.20.458
4pdaCTNNucleoside permease/0.458
4r20AERCytochrome P450 family 17 polypeptide 2/0.458
1aiqCB3Thymidylate synthase/0.457
1al8DHPPeroxisomal (S)-2-hydroxy-acid oxidase1.1.3.150.457
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.457
1hb1OCVIsopenicillin N synthase1.21.3.10.457
1hvyD16Thymidylate synthase2.1.1.450.457
1ikwEFZGag-Pol polyprotein2.7.7.490.457
1ju6LYAThymidylate synthase2.1.1.450.457
1l2iETCEstrogen receptor/0.457
1rfvADPPyridoxal kinase2.7.1.350.457
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.457
1txiTX5Vitamin D3 receptor/0.457
1vrwNAIEnoyl-ACP reductase/0.457
2fpcSCGStrictosidine synthase4.3.3.20.457
2pogWSTEstrogen receptor/0.457
2qk8MTXDihydrofolate reductase/0.457
2tscCB3Thymidylate synthase/0.457
2vx17X8Ephrin type-B receptor 42.7.10.10.457
2ydwWSHBromodomain-containing protein 2/0.457
2ywvADPPhosphoribosylaminoimidazole-succinocarboxamide synthase/0.457
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.457
3dmjGWEPol protein/0.457
3gobHXXDdmC/0.457
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.457
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.457
3unj0BXCyclin-dependent kinase 22.7.11.220.457
3vt45YIVitamin D3 receptor/0.457
3w0gW07Vitamin D3 receptor/0.457
3zze6XPHepatocyte growth factor receptor2.7.10.10.457
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.457
4fa60TAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4ia1BIVVitamin D3 receptor A/0.457
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.457
4l4aCAMCamphor 5-monooxygenase1.14.15.10.457
4lfiGNPCasein kinase II subunit alpha2.7.11.10.457
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.457
4rr6A3SProbable threonine--tRNA ligase 26.1.1.30.457
5k2dZMAAdenosine receptor A2a/0.457
1dyiFOLDihydrofolate reductase1.5.1.30.456
1ppjANYCytochrome b/0.456
1v0oINRCell division control protein 2 homolog2.7.11.220.456
1xalNAD3-dehydroquinate synthase/0.456
1xp9AIJEstrogen receptor/0.456
1ysx4EBSerum albumin/0.456
2gpvOHTEstrogen-related receptor gamma/0.456
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.456
2vcmM11Isopenicillin N synthase1.21.3.10.456
3fu83DMLaccase-11.10.3.20.456
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.456
3k1wBFXRenin3.4.23.150.456
3ns2PYVAbscisic acid receptor PYL2/0.456
3pd3A3TThreonine--tRNA ligase6.1.1.30.456
3rpr25ZCyclin-dependent kinase 22.7.11.220.456
3w0jT08Vitamin D3 receptor/0.456
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.456
4jqeANPCasein kinase II subunit alpha2.7.11.10.456
4okt198Androgen receptor/0.456
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.456
1e1nFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.455
1jlqSBNGag-Pol polyprotein2.7.7.490.455
1nq7ARLNuclear receptor ROR-beta/0.455
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.455
1qzfCB3Bifunctional dihydrofolate reductase-thymidylate synthase/0.455
1ro98BRcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.455
1rp4FADEndoplasmic oxidoreductin-11.8.40.455
1v7aFRCAdenosine deaminase3.5.4.40.455
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.455
2jb4A14Isopenicillin N synthase1.21.3.10.455
2o12FMNChorismate synthase/0.455
2qgtEEDEstrogen receptor/0.455
3c72CX1Geranylgeranyl transferase type-2 subunit beta2.5.1.600.455
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.455
3d7kD7KBenzaldehyde lyase/0.455
3dds26BGlycogen phosphorylase, liver form2.4.1.10.455
3dpd41APhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
3irn1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.455
3pl8FADPyranose 2-oxidase/0.455
3q2mCKISpectinomycin phosphotransferase/0.455
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.455
3w0aDS5Vitamin D3 receptor/0.455
3w0yDS4Vitamin D3 receptor/0.455
4boeCLRJapanin/0.455
4deg0JJHepatocyte growth factor receptor2.7.10.10.455
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
4jr3KJREpidermal growth factor receptor2.7.10.10.455
4pl9ADPEthylene receptor 1/0.455
4q0a4OAVitamin D3 receptor A/0.455
5iubCLRAdenosine receptor A2a/0.455
5kghACOPredicted acetyltransferase/0.455
1bygSTUTyrosine-protein kinase CSK/0.454
1ezfIN0Squalene synthase2.5.1.210.454
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.454
2dr3ADPUPF0273 protein PH0284/0.454
2vww7X2Ephrin type-B receptor 42.7.10.10.454
2zlcVDXVitamin D3 receptor/0.454
3ansS38Bifunctional epoxide hydrolase 23.3.2.100.454
3inxJZCHeat shock protein HSP 90-alpha/0.454
3m09RARDihydrofolate reductase1.5.1.30.454
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.454
4ajwVWNPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform2.7.1.1530.454
4dru0LNGenome polyprotein2.7.7.480.454
4g210VPVitamin D3 receptor A/0.454
4g2h0VQVitamin D3 receptor A/0.454
4gfg0XFTyrosine-protein kinase SYK2.7.10.20.454
4gk2L66Ephrin type-A receptor 32.7.10.10.454
4grb0XGCasein kinase II subunit alpha2.7.11.10.454
4hnc0UTMandelate racemase/0.454
4j26ESTEstrogen receptor beta/0.454
4kne1CYDihydrofolate reductase1.5.1.30.454
4mm729JNa(+):neurotransmitter symporter (Snf family)/0.454
4mv8ACPBiotin carboxylase6.3.4.140.454
4o71CPBBromodomain-containing protein 4/0.454
4otyLURProstaglandin G/H synthase 21.14.99.10.454
4rriA3TProbable threonine--tRNA ligase 26.1.1.30.454
4ure1PSCyclohexanol dehydrogenase/0.454
1g4tFTPThiamine-phosphate synthase/0.453
1iidNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.453
1k749CRRetinoic acid receptor RXR-alpha/0.453
1pjkANPCasein kinase II subunit alpha2.7.11.10.453
1u3r338Estrogen receptor beta/0.453
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.453
2fszOHTEstrogen receptor beta/0.453
2p1u4TNRetinoic acid receptor RXR-alpha/0.453
2ykiYKIHeat shock protein HSP 90-alpha/0.453
3dr1C5DVitamin D3 receptor A/0.453
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.453
3iqfE4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.453
3lalKRVGag-Pol polyprotein2.7.7.490.453
3m7rVDXVitamin D3 receptor/0.453
3owk18ECasein kinase II subunit alpha2.7.11.10.453
3q95ESLEstrogen receptor/0.453
3vtdTKDVitamin D3 receptor/0.453
4awq592Heat shock protein HSP 90-alpha/0.453
4bb5HD2Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.453
4g090VDHistidinol dehydrogenase/0.453
4iyg1HUStrictosidine synthase4.3.3.20.453
4j1p1K0Bromodomain-containing protein 2/0.453
4kfjFOLDihydrofolate reductase1.5.1.30.453
4yauFADNADPH--cytochrome P450 reductase/0.453
1bq1CB3Thymidylate synthase/0.452
1r0eDFNGlycogen synthase kinase-3 beta2.7.11.260.452
1rkgVD1Vitamin D3 receptor/0.452
1thnADPAnti-sigma F factor/0.452
1x78244Estrogen receptor beta/0.452
2b1z17MEstrogen receptor/0.452
2e08SAHDiphthine synthase/0.452
2ea1GPGRibonuclease I3.1.27.60.452
2eh5SAHDiphthine synthase/0.452
2gfdRDAEndoplasmin/0.452
2w0bCMWLanosterol 14-alpha demethylase1.14.13.700.452
2w6oOA3Biotin carboxylase6.3.4.140.452
2wgjVGHHepatocyte growth factor receptor2.7.10.10.452
2xizXIZSerine/threonine-protein kinase pim-12.7.11.10.452
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.452
3cr3ADPPTS-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL2.70.452
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.452
3ezpB3NHistone deacetylase 83.5.1.980.452
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
3nn6HNK6-hydroxy-L-nicotine oxidase/0.452
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
3s3vTOPDihydrofolate reductase1.5.1.30.452
3w0hW12Vitamin D3 receptor/0.452
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.452
4b4w9L9Bifunctional protein FolD/0.452
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.452
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
4h1j0YHProtein-tyrosine kinase 2-beta2.7.10.20.452
4i9z5BAcGMP-specific 3',5'-cyclic phosphodiesterase/0.452
4k9yK9YFocal adhesion kinase 12.7.10.20.452
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.452
4pkl1GHUncharacterized protein/0.452
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.452
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
1fwmCB3Thymidylate synthase/0.451
1kquBR4Phospholipase A2, membrane associated/0.451
1o6qR17Squalene--hopene cyclase4.2.1.1290.451
1og5SWFCytochrome P450 2C9/0.451
1opbRETRetinol-binding protein 2/0.451
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.451
1r6g442Thyroid hormone receptor beta/0.451
1rdt570Peroxisome proliferator-activated receptor gamma/0.451
1rh3MTXDihydrofolate reductase1.5.1.30.451
1s9pDESEstrogen-related receptor gamma/0.451
1ywrLI9Mitogen-activated protein kinase 14/0.451
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.451
2ovyPFJcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.451
2qboCAMCamphor 5-monooxygenase1.14.15.10.451
2ydvNECAdenosine receptor A2a/0.451
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3htjETEbrA repressor/0.451
3qlhT27Gag-Pol polyprotein2.7.7.490.451
3qpnPFKcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.451
3rinI2OMitogen-activated protein kinase 14/0.451
3w6hAZMCarbonic anhydrase 14.2.1.10.451
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.451
4fcd0T6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.451
4ib4ERM5-hydroxytryptamine receptor 2B/0.451
4l4dCAMCamphor 5-monooxygenase1.14.15.10.451
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.451
4lt63ATPoly(A) polymerase gamma2.7.7.190.451
4othDRNSerine/threonine-protein kinase N1/0.451
4rbs0RVMetallo-beta-lactamase type 2/0.451
4rrfA3SThreonine--tRNA ligase6.1.1.30.451
4ruoBIVVitamin D3 receptor A/0.451
1a80NDP2,5-diketo-D-gluconic acid reductase A1.1.1.3460.450
1dgbNDPCatalase1.11.1.60.450
1di8DTQCyclin-dependent kinase 22.7.11.220.450
1drfFOLDihydrofolate reductase1.5.1.30.450
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.450
1q9mROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.450
1s0zEB1Vitamin D3 receptor/0.450
1tilATPAnti-sigma F factor/0.450
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.450
1x8lOXRRetinol dehydratase/0.450
1yimCM4Estrogen receptor/0.450
2bx8AZQSerum albumin/0.450
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.450
2oscMUHAngiopoietin-1 receptor2.7.10.10.450
2qbnCAMCamphor 5-monooxygenase1.14.15.10.450
2rl52RLVascular endothelial growth factor receptor 22.7.10.10.450
2x4f16XMyosin light chain kinase family member 42.7.11.10.450
2y6o1N1Ephrin type-A receptor 42.7.10.10.450
2yee2ECHeat shock protein HSP 90-alpha/0.450
2znq401Peroxisome proliferator-activated receptor delta/0.450
3b8q900Vascular endothelial growth factor receptor 22.7.10.10.450
3blrCPBCyclin-dependent kinase 92.7.11.220.450
3cehAVEGlycogen phosphorylase, liver form2.4.1.10.450
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.450
3irxUDRGag-Pol polyprotein2.7.7.490.450
3mb601ICasein kinase II subunit alpha2.7.11.10.450
3njoPYVAbscisic acid receptor PYR1/0.450
3seqNXXGlutamine-dependent NAD(+) synthetase6.3.5.10.450
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.450
4alhA9PBromodomain-containing protein 2/0.450
4e37NDPCatalase1.11.1.60.450
4ez8DHFThymidylate synthase2.1.1.450.450
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4gkt0O1Queuine tRNA-ribosyltransferase2.4.2.290.450
4gw83RASerine/threonine-protein kinase pim-12.7.11.10.450
4ivw1GJEstrogen receptor/0.450
4kko1REGag-Pol polyprotein2.7.7.490.450
4l23X6KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.450
4o78SAVBromodomain-containing protein 4/0.450
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.450
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.450
4udcDEXGlucocorticoid receptor/0.450
4ypuSAMHistone-lysine N-methyltransferase ASH1L2.1.1.430.450
4zgsNADPutative D-lactate dehydrogenase/0.450
5a3cNADSIR2 family protein/0.450
5iu86DZAdenosine receptor A2a/0.450
1ia3TQ5Dihydrofolate reductase1.5.1.30.449
1jpaANPEphrin type-B receptor 22.7.10.10.449
1jutLYDThymidylate synthase/0.449
1mczRMNBenzoylformate decarboxylase4.1.1.70.449
1qknRALEstrogen receptor beta/0.449
1rf9DBRCamphor 5-monooxygenase1.14.15.10.449
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.449
1rx7FOLDihydrofolate reductase1.5.1.30.449
2bf7HBIPteridine reductase 11.5.1.330.449
2c31ADPOxalyl-CoA decarboxylase4.1.1.80.449
2cdaNAPGlucose 1-dehydrogenase/0.449
2itqITQEpidermal growth factor receptor2.7.10.10.449
2of4979Tyrosine-protein kinase Lck2.7.10.20.449
2oyuIMSProstaglandin G/H synthase 11.14.99.10.449
2w71L23Biotin carboxylase6.3.4.140.449
3a60STURibosomal protein S6 kinase beta-12.7.11.10.449
3c16FOKAdenylate cyclase type 2/0.449
3c16FOKAdenylate cyclase type 5/0.449
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.449
3c3dFO12-phospho-L-lactate transferase/0.449
3d90NOGProgesterone receptor/0.449
3dlgGWEGag-Pol polyprotein2.7.7.490.449
3gbk2PQPeroxisome proliferator-activated receptor gamma/0.449
3h4vDVPPteridine reductase 11.5.1.330.449
3hv3R49Mitogen-activated protein kinase 14/0.449
3iodA6DPantothenate synthetase6.3.2.10.449
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.449
3l0lHC3Nuclear receptor ROR-gamma/0.449
3l8sBFFMitogen-activated protein kinase 14/0.449
3mdvCL6Cholesterol 24-hydroxylase/0.449
3ox34X4Ribosyldihydronicotinamide dehydrogenase [quinone]/0.449
3pllF06Endothiapepsin3.4.23.220.449
3slkNDPPolyketide synthase extender module 2/0.449
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.449
3vf80JETyrosine-protein kinase SYK2.7.10.20.449
3vtcTK3Vitamin D3 receptor/0.449
4af3VX6Aurora kinase B2.7.11.10.449
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.449
4gk3L87Ephrin type-A receptor 32.7.10.10.449
4jbtASDCytochrome P450 monooxygenase/0.449
4jubTPPBenzoylformate decarboxylase4.1.1.70.449
5cshATPCasein kinase II subunit alpha2.7.11.10.449
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.449
5il2SAHN6-adenosine-methyltransferase 70 kDa subunit/0.449
5je2SAHMethyl transferase/0.449
1brpRTLRetinol-binding protein 4/0.448
1ndzFR5Adenosine deaminase3.5.4.40.448
1oynROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.448
1p93DEXGlucocorticoid receptor/0.448
1psdNADD-3-phosphoglycerate dehydrogenase1.1.1.950.448
1s3wTQTDihydrofolate reductase1.5.1.30.448
1s4dSAHUroporphyrinogen-III C-methyltransferase2.1.1.1070.448
1s9eADBGag-Pol polyprotein2.7.7.490.448
1trgCB3Thymidylate synthase/0.448
1tvrTB9Gag-Pol polyprotein2.7.7.490.448
1upw444Oxysterols receptor LXR-beta/0.448
1uyiPUZHeat shock protein HSP 90-alpha/0.448
1vrqFONSubunit alpha of sarocosine oxidase/0.448
1x7jGENEstrogen receptor beta/0.448
2bj4OHTEstrogen receptor/0.448
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
2ejzSAHDiphthine synthase/0.448
2g44T3OEstrogen receptor/0.448
2j0k4STFocal adhesion kinase 12.7.10.20.448
2mm3CHOGastrotropin/0.448
2obyNAPQuinone oxidoreductase PIG310.448
2q61SF1Peroxisome proliferator-activated receptor gamma/0.448
2q66ATPPoly(A) polymerase2.7.7.190.448
2vmyFFOSerine hydroxymethyltransferase/0.448
2vwv7X3Ephrin type-B receptor 42.7.10.10.448
2wonZZEGag-Pol polyprotein2.7.7.490.448
2zafFADNitroalkane oxidase1.7.3.10.448
3dyaPZLGag-Pol polyprotein2.7.7.490.448
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.448
3ln1CELProstaglandin G/H synthase 21.14.99.10.448
3mdmFJZCholesterol 24-hydroxylase/0.448
3t2zFADSulfide-quinone reductase/0.448
4at4T6EBDNF/NT-3 growth factors receptor2.7.10.10.448
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.448
4e730NRMitogen-activated protein kinase 82.7.11.240.448
4fewPP2Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.448
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4g95OAGDihydrofolate reductase1.5.1.30.448
4i41MIXSerine/threonine-protein kinase pim-12.7.11.10.448
4ia2BIVVitamin D3 receptor A/0.448
4kxl6C62'-deoxynucleoside 5'-phosphate N-hydrolase 1/0.448
7catNDPCatalase1.11.1.60.448
1c1c612Gag-Pol polyprotein2.7.7.490.447
1cjtFOKAdenylate cyclase type 2/0.447
1cjtFOKAdenylate cyclase type 5/0.447
1f4gTP4Thymidylate synthase/0.447
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.447
1rf7DHFDihydrofolate reductase1.5.1.30.447
1t88CAMCamphor 5-monooxygenase1.14.15.10.447
1x8vESLLanosterol 14-alpha demethylase1.14.13.700.447
2atiIHUGlycogen phosphorylase, liver form2.4.1.10.447
2bheBRYCyclin-dependent kinase 22.7.11.220.447
2gtk208Peroxisome proliferator-activated receptor gamma/0.447
2hw2RFPRifampin ADP-ribosyl transferase/0.447
2p20PRXAcetyl-coenzyme A synthetase/0.447
2rehFADNitroalkane oxidase1.7.3.10.447
2uzeC95Cyclin-dependent kinase 22.7.11.220.447
2wkmPFYHepatocyte growth factor receptor2.7.10.10.447
3bhlTHGThymidylate synthase/0.447
3dtcVINMitogen-activated protein kinase kinase kinase 92.7.11.250.447
3fkoFKOMitogen-activated protein kinase 14/0.447
3ft8MOJHeat shock protein HSP 90-alpha/0.447
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.447
3lakKR1Gag-Pol polyprotein2.7.7.490.447
3mg3ECHOrange carotenoid-binding protein/0.447
3nj0PYVAbscisic acid receptor PYL2/0.447
3p99LNPLanosterol 14-alpha-demethylase/0.447
3phiNDPShikimate dehydrogenase (NADP(+))/0.447
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.447
3rr3FLRProstaglandin G/H synthase 21.14.99.10.447
3t2yFADSulfide-quinone reductase/0.447
3vrvYSDVitamin D3 receptor/0.447
3vw8DF6Hepatocyte growth factor receptor2.7.10.10.447
3wavDWVEctonucleotide pyrophosphatase/phosphodiesterase family member 23.1.4.390.447
4fex0TOAminoglycoside 3'-phosphotransferase AphA1-IAB/0.447
4fhi0S4Vitamin D3 receptor A/0.447
4gk4L90Ephrin type-A receptor 32.7.10.10.447
4h1e10JBeta-secretase 13.4.23.460.447
4h4m494Gag-Pol polyprotein2.7.7.490.447
4i6gFADCryptochrome-2/0.447
4p6wMOFGlucocorticoid receptor/0.447
4ubsDIFPentalenic acid synthase1.14.15.110.447
5hyrESTEstrogen receptor/0.447
6coxS58Prostaglandin G/H synthase 21.14.99.10.447
1axwMTXThymidylate synthase/0.446
1f4fTP3Thymidylate synthase/0.446
1kziTHGThymidylate synthase/0.446
1lhvNOGSex hormone-binding globulin/0.446
1phhFADp-hydroxybenzoate hydroxylase/0.446
1r2jFADFkbI/0.446
1rdtL79Retinoic acid receptor RXR-alpha/0.446
1tkzH16Gag-Pol polyprotein2.7.7.490.446
1x7rGENEstrogen receptor/0.446
1yc2NADNAD-dependent protein deacylase 2/0.446
2a5yATPCell death protein 4/0.446
2fzwNADAlcohol dehydrogenase class-31.1.1.10.446
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.446
2harOCCVitamin D3 receptor/0.446
2hc4VDXVitamin D3 receptor A/0.446
2hziJINTyrosine-protein kinase ABL12.7.10.20.446
2pg0FADAcyl-CoA dehydrogenase/0.446
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.446
2qimZEAClass 10 plant pathogenesis-related protein/0.446
2vf0F89Thymidylate synthase/0.446
2y60M8FIsopenicillin N synthase1.21.3.10.446
2yemWSHBromodomain-containing protein 4/0.446
2z02ATPPhosphoribosylaminoimidazole-succinocarboxamide synthase6.3.2.60.446
3a4pDFQHepatocyte growth factor receptor2.7.10.10.446
3akzGSUGlutamate--tRNA ligase 2/0.446
3antS82Bifunctional epoxide hydrolase 23.3.2.100.446
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.446
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
3mec65BGag-Pol polyprotein2.7.7.490.446
3o57ZG2cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.446
3owj1ELCasein kinase II subunit alpha2.7.11.10.446
3p6oETGCamphor 5-monooxygenase1.14.15.10.446
3pce3HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.446
3pce3HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.446
3up3XCAaceDAF-12/0.446
3vgnFNNSteroid Delta-isomerase5.3.3.10.446
3zc3NAPFerredoxin--NADP reductase1.18.1.20.446
3zkuHCVIsopenicillin N synthase1.21.3.10.446
4ap7F47Hepatocyte growth factor receptor2.7.10.10.446
4at0FADPossible succinate dehydrogenase/0.446
4dpy2P0Mevalonate diphosphate decarboxylase/0.446
4e5yNDPGDP-L-fucose synthase1.1.1.2710.446
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
4f9aADPCell division cycle 7-related protein kinase2.7.11.10.446
4fcb0T7cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.446
4gg50J3Hepatocyte growth factor receptor2.7.10.10.446
4hgs15GCasein kinase I isoform gamma-32.7.11.10.446
4nc3ERM5-hydroxytryptamine receptor 2B/0.446
4oex5EOcGMP-specific 3',5'-cyclic phosphodiesterase/0.446
4rraA3TProbable threonine--tRNA ligase 26.1.1.30.446
5dgzL20Serine/threonine-protein kinase pim-12.7.11.10.446
5eypLOCTubulin beta chain/0.446
5iqiGNPBifunctional AAC/APH2.3.10.446
1ao8MTXDihydrofolate reductase1.5.1.30.445
1iyzNDPProbable quinone oxidoreductase/0.445
1l0lFMXCytochrome b/0.445
1m17AQ4Epidermal growth factor receptor2.7.10.10.445
1mvcBM6Retinoic acid receptor RXR-alpha/0.445
1nhz486Glucocorticoid receptor/0.445
1t13INI6,7-dimethyl-8-ribityllumazine synthase 2/0.445
1tg56454-hydroxyphenylpyruvate dioxygenase1.13.11.270.445
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.445
2aazCB3Thymidylate synthase2.1.1.450.445
2bfpH4BPteridine reductase 11.5.1.330.445
2bunFADAppA protein/0.445
2ds11CDCyclin-dependent kinase 22.7.11.220.445
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.445
2f4jVX6Tyrosine-protein kinase ABL12.7.10.20.445
2gs9SAHUncharacterized protein/0.445
2hwrDRDPeroxisome proliferator-activated receptor gamma/0.445
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.445
2izuP01Casein kinase I isoform gamma-32.7.11.10.445
2pulACPMethylthioribose kinase2.7.1.1000.445
2qw8NAPEugenol synthase 11.1.1.3180.445
2x9fX9FEphrin type-B receptor 42.7.10.10.445
2y37A54Nitric oxide synthase, inducible1.14.13.390.445
2yejXQKHeat shock protein HSP 90-alpha/0.445
2yjaESTEstrogen receptor/0.445
2zaxCAMCamphor 5-monooxygenase1.14.15.10.445
3bejMUFBile acid receptor/0.445
3bfb9ODPheromone-binding protein ASP1/0.445
3c14FOKAdenylate cyclase type 2/0.445
3c14FOKAdenylate cyclase type 5/0.445
3c7qXINVascular endothelial growth factor receptor 22.7.10.10.445
3fbuCOAAcetyltransferase, GNAT family/0.445
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.445
3ijdC2FMethylenetetrahydrofolate reductase/0.445
3iqzH4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.445
3lfcZ86Mitogen-activated protein kinase 14/0.445
3lpbNVBTyrosine-protein kinase JAK2/0.445
3rl35GPMetallophosphoesterase MPPED23.10.445
3s1cZIRCytokinin dehydrogenase 11.5.99.120.445
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.445
3t14FADSulfide-quinone reductase/0.445
3zy6GFBGDP-fucose protein O-fucosyltransferase 12.4.1.2210.445
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.445
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
4gub0Y4Casein kinase II subunit alpha2.7.11.10.445
4h6rFDAProline dehydrogenase/0.445
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.445
4ifvT27Gag-Pol polyprotein2.7.7.490.445
4lsl1YQGag-Pol polyprotein2.7.7.490.445
4p68MTXDihydrofolate reductase/0.445
4qjcIXEDihydrofolate reductase1.5.1.30.445
4rrxLURProstaglandin G/H synthase 21.14.99.10.445
4twnB96Ephrin type-A receptor 32.7.10.10.445
4zp1TPPPyruvate decarboxylase4.1.1.10.445
5d1bTSNHistone deacetylase 83.5.1.980.445
5irnADPNucleotide binding oligomerization domain containing 2/0.445
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.444
1equEQIEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1fm69CRRetinoic acid receptor RXR-alpha/0.444
1jujLYAThymidylate synthase2.1.1.450.444
1revTB9Gag-Pol polyprotein2.7.7.490.444
1rgsCMPcAMP-dependent protein kinase type I-alpha regulatory subunit/0.444
1rjkVDZVitamin D3 receptor/0.444
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.444
1ungALHCyclin-dependent-like kinase 52.7.11.10.444
1vkgCRIHistone deacetylase 83.5.1.980.444
2a1nCAMCamphor 5-monooxygenase1.14.15.10.444
2b01TUDPhospholipase A2, major isoenzyme3.1.1.40.444
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
2bifANP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 42.7.1.1050.444
2cx8SAHRibosomal RNA small subunit methyltransferase E/0.444
2ihuTP9N(2)-(2-carboxyethyl)arginine synthase/0.444
2kceD16Thymidylate synthase/0.444
2pvlP55Casein kinase II subunit alpha2.7.11.10.444
2qo9ANPEphrin type-A receptor 32.7.10.10.444
2uxoTACHTH-type transcriptional regulator TtgR/0.444
2vn1FK5Peptidylprolyl isomerase/0.444
2vqoTFGHistone deacetylase 43.5.1.980.444
2y30SM8Putative repressor SimReg2/0.444
3ar5TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.444
3b5iSAHIndole-3-acetate O-methyltransferase 1/0.444
3b9lAZZSerum albumin/0.444
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.444
3d3p20AcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.444
3d574HYThyroid hormone receptor beta/0.444
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.444
3exfTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.444
3exfTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.444
3hf6LX0Tryptophan 5-hydroxylase 11.14.16.40.444
3qh23NMThiazole tautomerase/0.444
3thrC2FGlycine N-methyltransferase2.1.1.200.444
3wiyLC6Induced myeloid leukemia cell differentiation protein Mcl-1/0.444
3zsh469Mitogen-activated protein kinase 14/0.444
4a8v2ANMajor pollen allergen Bet v 1-J/0.444
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
4hxs1A3Bromodomain-containing protein 4/0.444
4iaq2GM5-hydroxytryptamine receptor 1B/0.444
4iwv1J9Glucokinase2.7.1.20.444
4k7aDHTAndrogen receptor/0.444
4ko8AGSTransitional endoplasmic reticulum ATPase3.6.4.60.444
4lb2DM5Serum albumin/0.444
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.444
4rrdA3TProbable threonine--tRNA ligase 26.1.1.30.444
1bwlFMNNADPH dehydrogenase 11.6.99.10.443
1dhiMTXDihydrofolate reductase1.5.1.30.443
1eetBFUGag-Pol polyprotein2.7.7.490.443
1efvFADElectron transfer flavoprotein subunit alpha, mitochondrial/0.443
1h35R01Squalene--hopene cyclase4.2.1.1290.443
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.443
1n71COAAac(6')-Ii protein/0.443
1rd4L08Integrin alpha-L/0.443
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
1u0hFOKAdenylate cyclase type 2/0.443
1u0hFOKAdenylate cyclase type 5/0.443
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.443
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
2j14GNIPeroxisome proliferator-activated receptor delta/0.443
2oxtSAMGenome polyprotein/0.443
2pmdGNPTranslation initiation factor 2 subunit gamma/0.443
2qe4JJ3Estrogen receptor/0.443
2w6nOA2Biotin carboxylase6.3.4.140.443
2w98P1ZProstaglandin reductase 21.3.1.480.443
3cinNADMyo-inositol-1-phosphate synthase-related protein/0.443
3gxoMQAMitomycin biosynthesis 6-O-methyltransferase/0.443
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.443
3k2hLYABifunctional dihydrofolate reductase-thymidylate synthase/0.443
3r0tFU9Casein kinase II subunit alpha2.7.11.10.443
4a0sCO8Octenoyl-CoA reductase/carboxylase/0.443
4ap1NAPSteroid monooxygenase/0.443
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.443
4i1nFOLDihydrofolate reductase1.5.1.30.443
4nkvAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.443
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.443
4o7uTHFThymidylate synthase/0.443
4xivACPChemotaxis protein CheA2.7.13.30.443
4y12AGSSerine/threonine-protein kinase PknG2.7.11.10.443
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.443
5cyqT27Gag-Pol polyprotein2.7.7.490.443
5ej5TD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.443
5jr34MUCarminomycin 4-O-methyltransferase DnrK2.1.1.2920.443
1ay0TPPTransketolase 12.2.1.10.442
1bzfTMQDihydrofolate reductase1.5.1.30.442
1cjuFOKAdenylate cyclase type 2/0.442
1cjuFOKAdenylate cyclase type 5/0.442
1db56INPhospholipase A2, membrane associated/0.442
1dz6CAMCamphor 5-monooxygenase1.14.15.10.442
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.442
1jlcFTCGag-Pol polyprotein2.7.7.490.442
1phgMYTCamphor 5-monooxygenase1.14.15.10.442
1u9e397Estrogen receptor beta/0.442
1vceSAHDiphthine synthase/0.442
1w22NHBHistone deacetylase 83.5.1.980.442
1y0s331Peroxisome proliferator-activated receptor delta/0.442
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
2aclREARetinoic acid receptor RXR-alpha/0.442
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
2ay3MPPAromatic-amino-acid aminotransferase2.6.1.570.442
2huqSAHDiphthine synthase/0.442
2i40BLZCyclin-dependent kinase 22.7.11.220.442
2o4jVD4Vitamin D3 receptor/0.442
2of2547Tyrosine-protein kinase Lck2.7.10.20.442
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
2pvmP29Casein kinase II subunit alpha2.7.11.10.442
2v2zCDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.442
2vg5NNCGag-Pol polyprotein2.7.7.490.442
2vx07X7Ephrin type-B receptor 42.7.10.10.442
2vxoXMPGMP synthase [glutamine-hydrolyzing]6.3.5.20.442
3bjcWANcGMP-specific 3',5'-cyclic phosphodiesterase/0.442
3bzuA21Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.442
3g58988cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
3itzP66Mitogen-activated protein kinase 14/0.442
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.442
3jzfJZKBiotin carboxylase6.3.4.140.442
3of1CMPcAMP-dependent protein kinase regulatory subunit/0.442
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.442
3ollESTEstrogen receptor beta/0.442
3opdHIEHeat shock protein 83/0.442
3rf7NADIron-containing alcohol dehydrogenase/0.442
3sgtP09Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)/0.442
3uimANPBRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 12.7.10.10.442
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.442
3vrtYS2Vitamin D3 receptor/0.442
3zecANPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.442
3zvuA8SAbscisic acid receptor PYR1/0.442
4a4l939Serine/threonine-protein kinase PLK12.7.11.210.442
4awp99AHeat shock protein HSP 90-alpha/0.442
4e4m0NHTyrosine-protein kinase JAK2/0.442
4eb4D16Thymidylate synthase2.1.1.450.442
4ejh0QACytochrome P450 2A131.14.14.10.442
4g34924Eukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.442
4h380YXDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.442
4ia3BIVVitamin D3 receptor A/0.442
4l2xYL2Farnesyl pyrophosphate synthase2.5.1.100.442
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.442
4uyg73BBromodomain-containing protein 2/0.442
5cp4CAMCamphor 5-monooxygenase1.14.15.10.442
1cs4FOKAdenylate cyclase type 2/0.441
1cs4FOKAdenylate cyclase type 5/0.441
1d3gBREDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.441
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.441
1f20FADNitric oxide synthase, brain1.14.13.390.441
1f28F89Thymidylate synthase2.1.1.450.441
1hpzAAPGag-Pol polyprotein2.7.7.490.441
1i44ACPInsulin receptor2.7.10.10.441
1i5cADPChemotaxis protein CheA2.7.13.30.441
1owmFADDeoxyribodipyrimidine photo-lyase4.1.99.30.441
1qk35GPHypoxanthine-guanine-xanthine phosphoribosyltransferase2.4.2.220.441
1ro6ROLcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.441
1rvvINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.441
1s1wUC1Gag-Pol polyprotein2.7.7.490.441
1tf7ATPCircadian clock protein kinase KaiC2.7.11.10.441
1vruAAPGag-Pol polyprotein2.7.7.490.441
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
1y5xE89Queuine tRNA-ribosyltransferase2.4.2.290.441
1yrdCAMCamphor 5-monooxygenase1.14.15.10.441
1yye196Estrogen receptor beta/0.441
1zky689Estrogen receptor/0.441
2a4zBYMPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
2braFAD[F-actin]-methionine sulfoxide oxidase MICAL11.14.130.441
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.441
2ev9NAPShikimate dehydrogenase (NADP(+))/0.441
2f2cAP9Cyclin-dependent kinase 62.7.11.220.441
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.441
2iypNAP6-phosphogluconate dehydrogenase, decarboxylating1.1.1.440.441
2izrBRKCasein kinase I isoform gamma-32.7.11.10.441
2om9AJAPeroxisome proliferator-activated receptor gamma/0.441
2ovmAS0Progesterone receptor/0.441
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.441
2pixDHTAndrogen receptor/0.441
2puiADPMethylthioribose kinase2.7.1.1000.441
2r2nKYNKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.441
2uxpCLMHTH-type transcriptional regulator TtgR/0.441
2wsiFADFAD synthase2.7.7.20.441
3ad6KSCTyrosine-protein kinase Lck2.7.10.20.441
3c1xCKKHepatocyte growth factor receptor2.7.10.10.441
3kpkFADSulfide-quinone reductase/0.441
3megT27Gag-Pol polyprotein2.7.7.490.441
3o9lLPNRenin3.4.23.150.441
3oct1N1Tyrosine-protein kinase BTK2.7.10.20.441
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
3uli1N3Cyclin-dependent kinase 22.7.11.220.441
3x03ANPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1490.441
3zqtTESAndrogen receptor/0.441
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4b8mVX6Aurora kinase B-A2.7.11.10.441
4bqpVMYEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
4dma0L8Estrogen receptor/0.441
4ffrATPUncharacterized protein/0.441
4g1d0VKVitamin D3 receptor A/0.441
4g2fC07Ephrin type-A receptor 32.7.10.10.441
4ict1EDMycocyclosin synthase1.14.21.90.441
4n1gCEIObelin/0.441
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.441
4ocvANPAminoglycoside phosphotransferase/0.441
4qoeFADRibosyldihydronicotinamide dehydrogenase [quinone]/0.441
4tjy3GNTankyrase-22.4.2.300.441
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.441
4z44FADFlavin-dependent tryptophan halogenase PrnA1.14.19.90.441
5bp9SAHPutative methyltransferase protein/0.441
5hwpCOAHydroxymethylglutaryl-CoA synthase/0.441
5koiNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.441
5l7dCLRSmoothened homolog/0.441
1culFOKAdenylate cyclase type 2/0.440
1culFOKAdenylate cyclase type 5/0.440
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.440
1hnvTBOGag-Pol polyprotein2.7.7.490.440
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.440
1rkpIBMcGMP-specific 3',5'-cyclic phosphodiesterase/0.440
1suoCPZCytochrome P450 2B41.14.14.10.440
1tktH12Gag-Pol polyprotein2.7.7.490.440
1uymPU3Heat shock protein HSP 90-beta/0.440
1xjdSTUProtein kinase C theta type2.7.11.130.440
1zidZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.440
1zx1CB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.440
2b5j3ACGag-Pol polyprotein2.7.7.490.440
2cvzNDP3-hydroxyisobutyrate dehydrogenase/0.440
2ek7SAHDiphthine synthase/0.440
2hbhXE4Vitamin D3 receptor A/0.440
2itnANPEpidermal growth factor receptor2.7.10.10.440
2j7yE3OEstrogen receptor beta/0.440
2r0pK2CPutative FAD-monooxygenase/0.440
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.440
3afhGSUGlutamate--tRNA ligase 2/0.440
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
3cjtSAHRibosomal protein L11 methyltransferase2.1.10.440
3cquCQURAC-alpha serine/threonine-protein kinase2.7.11.10.440
3hy310F5-formyltetrahydrofolate cyclo-ligase6.3.3.20.440
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
3igoANPCalmodulin-domain protein kinase 1, putative/0.440
3k3kA8SAbscisic acid receptor PYR1/0.440
3lz6A0DCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
3oqkS52Renin3.4.23.150.440
3qfvNM7Serine/threonine-protein kinase MRCK beta2.7.11.10.440
3qppPFWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
3th8TH9Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.440
3uleC69Actin-related protein 3/0.440
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.440
4appN53Serine/threonine-protein kinase PAK 42.7.11.10.440
4efuEFUHeat shock protein HSP 90-alpha/0.440
4fnyI3KALK tyrosine kinase receptor2.7.10.10.440
4g310WHEukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.440
4id5T27Gag-Pol polyprotein2.7.7.490.440
4jia1K3Tyrosine-protein kinase JAK2/0.440
4jlk1NODeoxycytidine kinase2.7.1.740.440
4l49CAMCamphor 5-monooxygenase1.14.15.10.440
4lgaA2OAbscisic acid receptor PYL2/0.440
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.440
4o2bLOCTubulin beta-2B chain/0.440
4qknJMSAlpha-ketoglutarate-dependent dioxygenase FTO/0.440
4rrgA3TThreonine--tRNA ligase6.1.1.30.440
5d7pOCZNAD-dependent protein deacetylase sirtuin-23.5.10.440
5e92ANPTGF-beta receptor type-22.7.11.300.440
3qakUKAAdenosine receptor A2a/0.440