sc-PDB

List of CHEMBLId :

This value allows a number of roughly comparable measures of half-maximal response concentration/potency/affinity to be compared on a negative logarithmic scale (e.g., an IC50 measurement of 1nM would have a pChEMBL value of 9).

Uniprot Annotation

Name:	Serine hydroxymethyltransferase, cytosolic
ID:	GLYC_MOUSE
AC:	P50431
Organism:	Mus musculus
Reign:	Eukaryota
TaxID:	10090
EC Number:	/

---

Chains:

Chain Name:	Percentage of Residues within binding site
A	68 %
B	32 %

---

Ligand binding site composition:

B-Factor:	81.026
Number of residues:	38
Including
Standard Amino Acids:	37
Non Standard Amino Acids:	1
Water Molecules:	0
Cofactors:
Metals:

---

Cavity properties

Ligandability	Volume (Å3)
0.898	496.125

% Hydrophobic	% Polar
52.38	47.62
According to VolSite

HET Code:	THF
Formula:	C20H21N7O7
Molecular weight:	471.423 g/mol
DrugBank ID:	DB02800
Buried Surface Area:	58.43 %
Polar Surface area:	224.7 Å2

Number of
H-Bond Acceptors:	13
H-Bond Donors:	5
Rings:	3
Aromatic rings:	1
Anionic atoms:	2
Cationic atoms:	0
Rule of Five Violation:	1
Rotatable Bonds:	10

---

Mass center Coordinates

X	Y	Z
109.434	71.3457	92.1381

• 2D View
• 3D View