sc-PDB

List of CHEMBLId :

This value allows a number of roughly comparable measures of half-maximal response concentration/potency/affinity to be compared on a negative logarithmic scale (e.g., an IC50 measurement of 1nM would have a pChEMBL value of 9).

Uniprot Annotation

Name:	Biotin carboxylase
ID:	ACCC_ECOLI
AC:	P24182
Organism:	Escherichia coli
Reign:	Bacteria
TaxID:	83333
EC Number:	6.3.4.14

---

Chains:

Chain Name:	Percentage of Residues within binding site
A	100 %

---

Ligand binding site composition:

B-Factor:	21.114
Number of residues:	35
Including
Standard Amino Acids:	31
Non Standard Amino Acids:	0
Water Molecules:	4
Cofactors:
Metals:

---

Cavity properties

Ligandability	Volume (Å3)
1.017	1211.625

% Hydrophobic	% Polar
39.55	60.45
According to VolSite

HET Code:	OA2
Formula:	C18H17N3O2
Molecular weight:	307.346 g/mol
DrugBank ID:	DB08315
Buried Surface Area:	62.44 %
Polar Surface area:	72.36 Å2

Number of
H-Bond Acceptors:	3
H-Bond Donors:	1
Rings:	3
Aromatic rings:	3
Anionic atoms:	0
Cationic atoms:	0
Rule of Five Violation:	0
Rotatable Bonds:	5

---

Mass center Coordinates

X	Y	Z
3.39096	-22.1291	23.9202

• 2D View
• 3D View