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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2trsIPLTryptophan synthase alpha chain

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2trsIPLTryptophan synthase alpha chain/1.000
1a50FIPTryptophan synthase alpha chain/0.743
1a5sFIPTryptophan synthase alpha chain/0.689
2clhF19Tryptophan synthase alpha chain/0.685
1k8zIAGTryptophan synthase alpha chain/0.621
2rh9IGPTryptophan synthase alpha chain/0.617
4xugF9FTryptophan synthase alpha chain/0.611
1fuyFIPTryptophan synthase alpha chain/0.608
2cleF6FTryptophan synthase alpha chain/0.564
2clfF6FTryptophan synthase alpha chain/0.557
1beuIPLTryptophan synthase alpha chain/0.541
4y6gF6FTryptophan synthase alpha chain/0.535
2vqoTFGHistone deacetylase 43.5.1.980.524
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.522
3zecANPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.521
3zrrPXGSerine-pyruvate aminotransferase (AgxT)/0.520
4x7zZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.520
4rh10TTSpore photoproduct lyase/0.519
2wksCB63-dehydroquinate dehydratase4.2.1.100.518
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.517
3sl2ATPSensor histidine kinase WalK/0.517
1ro6ROLcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.515
1u0wSTLChalcone synthase 22.3.1.740.514
4fhf0TTSpore photoproduct lyase/0.513
3jziJZLBiotin carboxylase6.3.4.140.510
4x81MVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.510
4zqcF6FTryptophan synthase alpha chain/0.508
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.506
4dvi2IWTankyrase-12.4.2.300.506
3k1wBFXRenin3.4.23.150.504
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.503
3wqmB29Diterpene synthase3.1.7.80.503
1zdwFLVPrenyltransferase/0.502
2kceD16Thymidylate synthase/0.501
2y05RALProstaglandin reductase 1/0.500
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.500
4bvaT3Ketimine reductase mu-crystallin1.5.1.250.500
2xlsFADPutative flavin-containing monooxygenase/0.499
3jwm5WBDihydrofolate reductase/0.498
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.498
2znnS44Peroxisome proliferator-activated receptor alpha/0.497
3r7mSUZAldo-keto reductase family 1 member C3/0.497
4x7uZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.497
2c9bPUG6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.496
4e32DWNMethyltransferase/0.496
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.494
2cbrA80Cellular retinoic acid-binding protein 1/0.494
2jj2ANPATP synthase subunit beta, mitochondrial3.6.3.140.494
3n33AESBeta-peptidyl aminopeptidase BapA/0.494
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.494
4x7wMVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.494
1zz1SHHHistone deacetylase-like amidohydrolase3.5.10.493
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.493
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.493
4eqwCOACoenzyme A disulfide reductase/0.493
5epvACPBlue-light-activated histidine kinase2.7.13.30.493
1kfbIGPTryptophan synthase alpha chain/0.492
1rsgFADPolyamine oxidase FMS1/0.492
2ovyPFJcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.492
2rhgIGPTryptophan synthase alpha chain/0.492
2uxoTACHTH-type transcriptional regulator TtgR/0.492
2ydoADNAdenosine receptor A2a/0.492
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.492
3pm1ETHTH-type transcriptional regulator QacR/0.492
4wx2F6FTryptophan synthase alpha chain/0.492
4wx2F6FTryptophan synthase beta chain4.2.1.200.492
1kqgMGDFormate dehydrogenase, nitrate-inducible, major subunit1.1.5.60.491
1w22NHBHistone deacetylase 83.5.1.980.491
3br3ETHTH-type transcriptional regulator QacR/0.490
3p9tTCLRepressor/0.490
1zg32HIIsoflavone 4'-O-methyltransferase/0.489
4xoqF42Coenzyme F420:L-glutamate ligase/0.489
2jizANPATP synthase subunit beta, mitochondrial3.6.3.140.488
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.488
3t8xT8XT-cell surface glycoprotein CD1b/0.488
4qe6JN3Bile acid receptor/0.488
1upw444Oxysterols receptor LXR-beta/0.487
1xoqROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.487
2pobGW4Peroxisome proliferator-activated receptor gamma/0.487
2z7gEH9Adenosine deaminase3.5.4.40.487
3d74NBBPheromone-binding protein ASP1/0.487
3h3t16HCollagen type IV alpha-3-binding protein/0.487
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.487
4bufF36Tankyrase-22.4.2.300.487
5kjePFBAlcohol dehydrogenase E chain1.1.1.10.487
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.486
3kk6CELProstaglandin G/H synthase 11.14.99.10.486
3tg4SAMN-lysine methyltransferase SMYD2/0.486
1pwyAC2Purine nucleoside phosphorylase2.4.2.10.485
2po7CHDFerrochelatase, mitochondrial4.99.1.10.485
2vbpVB1Isopenicillin N synthase1.21.3.10.485
2wo7ASVIsopenicillin N synthase1.21.3.10.485
2zevB71Geranylgeranyl pyrophosphate synthase/0.485
3eon341Glutaryl-CoA dehydrogenase/0.485
3l6jZ90Alr2278 protein/0.485
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.485
4jv41ORcAMP-dependent protein kinase type I-alpha regulatory subunit/0.485
5dc5B3NHistone deacetylase 83.5.1.980.485
5kjcPFBAlcohol dehydrogenase E chain1.1.1.10.485
1ndzFR5Adenosine deaminase3.5.4.40.484
1yqzCOACoenzyme A disulfide reductase/0.484
2vcmM11Isopenicillin N synthase1.21.3.10.484
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.484
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.484
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.484
3ruhNADUDP-N-acetylglucosamine 4-epimerase/0.484
4az3S35Lysosomal protective protein3.4.16.50.484
4g8bHL6Alpha/beta hydrolase fold protein/0.484
4la7A1OAbscisic acid receptor PYL2/0.484
1olmVTQSEC14-like protein 2/0.483
2w4qCBWProstaglandin reductase 21.3.1.480.483
3occDIHPurine nucleoside phosphorylase DeoD-type/0.483
3w5tLHPVitamin D3 receptor/0.483
4bb3KKAIsopenicillin N synthase1.21.3.10.483
4eqrCOACoenzyme A disulfide reductase/0.483
1c7oPPGHemolysin/0.482
1el4CTZObelin/0.482
1mvsDTMDihydrofolate reductase1.5.1.30.482
2hpsCTZCa2+-triggered coelenterazine-binding protein 1/0.482
2r6jNDPEugenol synthase 11.1.1.3180.482
3v9y24LPeroxisome proliferator-activated receptor gamma/0.482
3uzaT4GAdenosine receptor A2a/0.482
1bifAGS6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 42.7.1.1050.481
1jx0DFVChalcone--flavonone isomerase 15.5.1.60.481
1zgaHMKIsoflavone 4'-O-methyltransferase/0.481
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.481
3gncQQQGlutaryl-CoA dehydrogenase/0.481
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.481
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.481
4h9tHL4Phosphotriesterase/0.481
5cdgPFBAlcohol dehydrogenase E chain1.1.1.10.481
1ej3CZHAequorin-2/0.480
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.480
1qoqIGPTryptophan synthase alpha chain/0.480
2vqqTFGHistone deacetylase 43.5.1.980.480
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.480
3otqMZLBifunctional epoxide hydrolase 23.3.2.100.480
3zkyWT4Isopenicillin N synthase1.21.3.10.480
4ea13RXDehydrosqualene synthase/0.480
4eqsCOACoenzyme A disulfide reductase/0.480
4hlf15ZTankyrase-22.4.2.300.480
4jlj1NMDeoxycytidine kinase2.7.1.740.480
1fvpFMANon-fluorescent flavoprotein/0.479
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.479
1stdBFSScytalone dehydratase4.2.1.940.479
2ay3MPPAromatic-amino-acid aminotransferase2.6.1.570.479
2fzhDH1Dihydrofolate reductase1.5.1.30.479
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.479
3g58988cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.479
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.479
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.479
3zoiM2WIsopenicillin N synthase1.21.3.10.479
4f9aADPCell division cycle 7-related protein kinase2.7.11.10.479
4nieNBHNuclear receptor ROR-gamma/0.479
4r21STRCytochrome P450 family 17 polypeptide 2/0.479
5bp9SAHPutative methyltransferase protein/0.479
1fmlRTLRetinol dehydratase/0.478
1pz1NAPGeneral stress protein 69/0.478
2mm3CHOGastrotropin/0.478
2zb8IMNProstaglandin reductase 21.3.1.480.478
3uayADNPurine nucleoside phosphorylase DeoD-type/0.478
3vf60H6Glucokinase2.7.1.20.478
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.478
4dk70KSOxysterols receptor LXR-beta/0.478
4iae1DXAlr2278 protein/0.478
1blzACVIsopenicillin N synthase1.21.3.10.477
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.477
2gtbAZPOrf1ab polyprotein/0.477
3acy702Dehydrosqualene synthase/0.477
4do30LAFatty-acid amide hydrolase 13.5.1.990.477
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.477
4geb0LDKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.477
4tyj0LIFibroblast growth factor receptor 42.7.10.10.477
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.477
1bk0ACVIsopenicillin N synthase1.21.3.10.476
3g4lROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.476
4bfpSWYTankyrase-22.4.2.300.476
4fhh0U3Vitamin D3 receptor A/0.476
4rr7A3SProbable threonine--tRNA ligase 26.1.1.30.476
1ppjANYCytochrome b/0.475
1w6jR71Lanosterol synthase5.4.99.70.475
2iviACWIsopenicillin N synthase1.21.3.10.475
3aezGDPPantothenate kinase2.7.1.330.475
3oq6PFBAlcohol dehydrogenase E chain1.1.1.10.475
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.475
4klaCHDFerrochelatase, mitochondrial4.99.1.10.475
4y1bNAPAntE/0.475
5c1mCLRMu-type opioid receptor/0.475
1e1qADPATP synthase subunit beta, mitochondrial3.6.3.140.474
2fziDH3Dihydrofolate reductase1.5.1.30.474
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.474
2m56CAMCamphor 5-monooxygenase1.14.15.10.474
2y60M8FIsopenicillin N synthase1.21.3.10.474
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.474
3gwfNAPCyclohexanone monooxygenase/0.474
3k47D09Dihydrofolate reductase1.5.1.30.474
3of3DIHPurine nucleoside phosphorylase DeoD-type 1/0.474
3qlzQLZUncharacterized protein/0.474
4b4w9L9Bifunctional protein FolD/0.474
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.474
1a8t061Metallo-beta-lactamase type 2/0.473
1k7fIAVTryptophan synthase alpha chain/0.473
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.473
1obnASVIsopenicillin N synthase1.21.3.10.473
2g274LGRenin3.4.23.150.473
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.473
3g5hYTTMycocyclosin synthase1.14.21.90.473
3h3qH13Collagen type IV alpha-3-binding protein/0.473
4a83DXCMajor pollen allergen Bet v 1-A/0.473
4bfuZVUPantothenate kinase2.7.1.330.473
4biwANPSensor histidine kinase CpxA/0.473
4g7gVFVLanosterol 14-alpha-demethylase/0.473
4h9753SDihydrofolate reductase1.5.1.30.473
4k9yK9YFocal adhesion kinase 12.7.10.20.473
4p5fAR6Inosine-uridine nucleoside N-ribohydrolase/0.473
4rraA3TProbable threonine--tRNA ligase 26.1.1.30.473
1a5bIGPTryptophan synthase alpha chain/0.472
1dlrMXADihydrofolate reductase1.5.1.30.472
1oynROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.472
1uzwCDHIsopenicillin N synthase1.21.3.10.472
2bu9HFVIsopenicillin N synthase1.21.3.10.472
2i4tUA2Purine nucleoside phosphorylase, putative/0.472
3h3sH15Collagen type IV alpha-3-binding protein/0.472
3l8sBFFMitogen-activated protein kinase 14/0.472
3oagLPQRenin3.4.23.150.472
3sl8JN7cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.472
4ky404JBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.472
4pl9ADPEthylene receptor 1/0.472
5hwoHMGHydroxymethylglutaryl-CoA synthase/0.472
5kcpPFBAlcohol dehydrogenase E chain1.1.1.10.472
1re0AFBADP-ribosylation factor 1/0.471
1re0AFBARF guanine-nucleotide exchange factor 1/0.471
1s5kCOAAminoglycoside N(6')-acetyltransferase type 1/0.471
1wp4NDP3-hydroxyisobutyrate dehydrogenase/0.471
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.471
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.471
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.471
3nxtD2EDihydrofolate reductase1.5.1.30.471
4h380YXDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.471
4j6cSTRCytochrome P450 monooxygenase/0.471
4oex5EOcGMP-specific 3',5'-cyclic phosphodiesterase/0.471
4psbGA3Cytokinin-specific binding protein/0.471
4ruoBIVVitamin D3 receptor A/0.471
5k2aZMAAdenosine receptor A2a/0.471
1dghNDPCatalase1.11.1.60.470
1g63FMNEpidermin decarboxylase4.1.10.470
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.470
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.470
3a1l2CCCytochrome P450/0.470
3b9lAZZSerum albumin/0.470
3iktNADRedox-sensing transcriptional repressor Rex/0.470
4hkkAGITankyrase-22.4.2.300.470
4jbtASDCytochrome P450 monooxygenase/0.470
4l98LRGPeroxisome proliferator-activated receptor gamma/0.470
4qa0SHHHistone deacetylase 83.5.1.980.470
1a80NDP2,5-diketo-D-gluconic acid reductase A1.1.1.3460.469
1s36CEIObelin/0.469
1zgv501Prothrombin3.4.21.50.469
2cjfRP43-dehydroquinate dehydratase4.2.1.100.469
2j5sKTAAlr4455 protein/0.469
3arvSAUChitinase A/0.469
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.469
3p0eBAUUridine phosphorylase 22.4.2.30.469
3ptzUDXUDP-glucose 6-dehydrogenase1.1.1.220.469
3tfn2CJDehydrosqualene synthase/0.469
4azwATPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.469
4h9506UDihydrofolate reductase1.5.1.30.469
4hxyNDPPlm1/0.469
4ipw1G7Mycocyclosin synthase1.14.21.90.469
4l321VFTankyrase-22.4.2.300.469
4l5b1UXDeoxycytidine kinase2.7.1.740.469
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.469
4ng5PFBAlcohol dehydrogenase E chain1.1.1.10.469
4oew5IOcGMP-specific 3',5'-cyclic phosphodiesterase/0.469
1p8dCO1Oxysterols receptor LXR-beta/0.468
1pkfEPDEpothilone C/D epoxidase1.140.468
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.468
1rvvINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.468
1w06W05Isopenicillin N synthase1.21.3.10.468
2bgsNDPAldose reductase1.1.1.210.468
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.468
3jpuTY4Transcriptional activator protein LasR/0.468
3kytHC2Nuclear receptor ROR-gamma/0.468
3o9lLPNRenin3.4.23.150.468
3qj5022Alcohol dehydrogenase class-31.1.1.10.468
3x0a5GPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1490.468
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.468
4k4fK4FTankyrase-12.4.2.300.468
4l8u9AZSerum albumin/0.468
4rrhA3SProbable threonine--tRNA ligase 26.1.1.30.468
1crbRTLRetinol-binding protein 1/0.467
1dhfFOLDihydrofolate reductase1.5.1.30.467
1drbMTXDihydrofolate reductase1.5.1.30.467
1hb1OCVIsopenicillin N synthase1.21.3.10.467
1pke2FDPurine nucleoside phosphorylase DeoD-type/0.467
1pqc444Oxysterols receptor LXR-beta/0.467
1rx7FOLDihydrofolate reductase1.5.1.30.467
1w83L11Mitogen-activated protein kinase 14/0.467
2az3CDPNucleoside diphosphate kinase/0.467
2jc6QPPCalcium/calmodulin-dependent protein kinase type 1D2.7.11.170.467
2qw034Z4-chlorobenzoyl CoA ligase/0.467
3g70A5TRenin3.4.23.150.467
3zcnATPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.467
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.467
4bj9UHBTankyrase-22.4.2.300.467
4kzl20DTankyrase-22.4.2.300.467
4mwzSAMPhosphoethanolamine N-methyltransferase, putative/0.467
1fm6BRLPeroxisome proliferator-activated receptor gamma/0.466
1qzfCB3Bifunctional dihydrofolate reductase-thymidylate synthase/0.466
2bktRPFRenin3.4.23.150.466
2isc223Purine nucleoside phosphorylase, putative/0.466
2y30SM8Putative repressor SimReg2/0.466
3fhxPLPPyridoxal kinase2.7.1.350.466
3vri1KXHLA class I histocompatibility antigen, B-57 alpha chain/0.466
4jauADPSensor histidine kinase/0.466
4kak06UDihydrofolate reductase1.5.1.30.466
4n3r2GUTankyrase-12.4.2.300.466
5d7pOCZNAD-dependent protein deacetylase sirtuin-23.5.10.466
2a4nCOAAac(6')-Ii protein/0.465
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.465
2y6fM9FIsopenicillin N synthase1.21.3.10.465
3a1cACPProbable copper-exporting P-type ATPase A3.6.3.540.465
3adaNADSubunit alpha of sarocosine oxidase/0.465
3g4kROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.465
3gwfFADCyclohexanone monooxygenase/0.465
3oafOAGDihydrofolate reductase1.5.1.30.465
3sp6IL2Peroxisome proliferator-activated receptor alpha/0.465
3ziaADPATP synthase subunit beta, mitochondrial3.6.3.140.465
3zlnH0YBcl-2-like protein 1/0.465
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.465
4g2wNI0cGMP-specific 3',5'-cyclic phosphodiesterase/0.465
4ge90L0Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.465
4iarERM5-hydroxytryptamine receptor 1B/0.465
4jqh1MFAlr2278 protein/0.465
4o8fBRLPeroxisome proliferator-activated receptor gamma/0.465
4qi9MTXDihydrofolate reductase/0.465
4uugPXGBranched-chain amino acid aminotransferase, putative/0.465
4zgsNADPutative D-lactate dehydrogenase/0.465
5kj1PFBAlcohol dehydrogenase E chain1.1.1.10.465
1aoeGW3Dihydrofolate reductase1.5.1.30.464
1k4gAIQQueuine tRNA-ribosyltransferase2.4.2.290.464
1yhjR6CPyridoxal kinase2.7.1.350.464
2fzjDH3Dihydrofolate reductase1.5.1.30.464
2hk9NAPShikimate dehydrogenase (NADP(+))/0.464
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.464
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.464
2pauD5M5'-deoxynucleotidase YfbR/0.464
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.464
3cotSTR3-oxo-5-beta-steroid 4-dehydrogenase/0.464
3eej53RUncharacterized protein/0.464
3n2eOSAShikimate kinase2.7.1.710.464
3ruaNADUDP-N-acetylglucosamine 4-epimerase/0.464
3sp9IL2Peroxisome proliferator-activated receptor delta/0.464
3up3XCAaceDAF-12/0.464
3w0aDS5Vitamin D3 receptor/0.464
4bu908CTankyrase-22.4.2.300.464
4emaBRLPeroxisome proliferator-activated receptor gamma/0.464
4g2yNI5cGMP-specific 3',5'-cyclic phosphodiesterase/0.464
4hlm16STankyrase-22.4.2.300.464
4jlm1NNDeoxycytidine kinase2.7.1.740.464
4ktl1CQCytochrome P450/0.464
5cdtPFBAlcohol dehydrogenase E chain1.1.1.10.464
5g53NECAdenosine receptor A2a/0.464
3sn6P0GBeta-2 adrenergic receptor/0.464
1hb3SCVIsopenicillin N synthase1.21.3.10.463
1ia4TQ6Dihydrofolate reductase1.5.1.30.463
1jqiFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial/0.463
1kt3RTLRetinol-binding protein 4/0.463
2getCOKPantothenate kinase2.7.1.330.463
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.463
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.463
2v95HCYCorticosteroid-binding globulin/0.463
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.463
2zsaADPPantothenate kinase2.7.1.330.463
3cseN22Uncharacterized protein/0.463
3uzzTES3-oxo-5-beta-steroid 4-dehydrogenase/0.463
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.463
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.463
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.463
4l0v1V1Tankyrase-22.4.2.300.463
4l17DNQGlutamate receptor 2/0.463
4qii2NE1,4-dihydroxy-2-naphthoyl-CoA synthase/0.463
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.463
1f3bGBXGlutathione S-transferase A12.5.1.180.462
1muuGDXGDP-mannose 6-dehydrogenase1.1.1.1320.462
1ove358Mitogen-activated protein kinase 14/0.462
1qv1CZHObelin/0.462
1rp4FADEndoplasmic oxidoreductin-11.8.40.462
1w0kADPATP synthase subunit alpha, mitochondrial/0.462
1w0kADPATP synthase subunit beta, mitochondrial3.6.3.140.462
1xwfADNAdenosylhomocysteinase3.3.1.10.462
2e20B4PPropionate kinase/0.462
2fs4PZ1Renin3.4.23.150.462
2gtk208Peroxisome proliferator-activated receptor gamma/0.462
2q3eUPGUDP-glucose 6-dehydrogenase1.1.1.220.462
2q7hYLYPyrrolysine--tRNA ligase/0.462
3ar5TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.462
3o57ZG2cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.462
3uic09TEnoyl-[acyl-carrier-protein] reductase [NADH]/0.462
3vt7VDXVitamin D3 receptor/0.462
3w0iO11Vitamin D3 receptor/0.462
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.462
1kqwRTLCellular retinol-binding protein type II/0.461
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.461
1w29TS06,7-dimethyl-8-ribityllumazine synthase2.5.1.780.461
1yw9A84Methionine aminopeptidase 2/0.461
1zeoC01Peroxisome proliferator-activated receptor gamma/0.461
2a3bCFFEndochitinase B13.2.1.140.461
2c1zKMPAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.461
2jfz003Glutamate racemase/0.461
2pg0FADAcyl-CoA dehydrogenase/0.461
2w9hTOPDihydrofolate reductase1.5.1.30.461
2z9dFMNFMN-dependent NADH-azoreductase/0.461
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.461
3ndvAICBeta-peptidyl aminopeptidase BapA/0.461
3u8hBHPPhospholipase A2, membrane associated/0.461
3vev0H4Glucokinase2.7.1.20.461
4jva1ORcAMP-dependent protein kinase type II-beta regulatory subunit/0.461
4jwr1MYE3 ubiquitin-protein ligase Mdm26.3.20.461
4pnrG18Tankyrase-22.4.2.300.461
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.461
5dozNDPJamJ/0.461
1i5cADPChemotaxis protein CheA2.7.13.30.460
1nceCB3Thymidylate synthase/0.460
1pr6XYAPurine nucleoside phosphorylase DeoD-type/0.460
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.460
1rx4DDFDihydrofolate reductase1.5.1.30.460
1xu7CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.460
2e0nSAHPrecorrin-2 C20-methyltransferase/0.460
2fm0M98cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.460
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.460
3akn11DFatty acid-binding protein, intestinal/0.460
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.460
3f3y4OABile salt sulfotransferase2.8.2.140.460
3g6zA7TRenin3.4.23.150.460
3h3r14HCollagen type IV alpha-3-binding protein/0.460
3oct1N1Tyrosine-protein kinase BTK2.7.10.20.460
3p0fBAUUridine phosphorylase 22.4.2.30.460
3p6nDSOCamphor 5-monooxygenase1.14.15.10.460
3s1aATPCircadian clock protein kinase KaiC2.7.11.10.460
4dbw511Aldo-keto reductase family 1 member C3/0.460
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.460
4g95OAGDihydrofolate reductase1.5.1.30.460
4i9i1DYTankyrase-12.4.2.300.460
4ng2OHNTranscriptional activator protein LasR/0.460
4qppSAHProtein arginine N-methyltransferase 6/0.460
4rr8A3SProbable threonine--tRNA ligase 26.1.1.30.460
5kj6PFBAlcohol dehydrogenase E chain1.1.1.10.460
13gsSASGlutathione S-transferase P2.5.1.180.459
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.459
1fmjRTLRetinol dehydratase/0.459
1kkq471Peroxisome proliferator-activated receptor alpha/0.459
1qjfACSIsopenicillin N synthase1.21.3.10.459
1rkhVD2Vitamin D3 receptor/0.459
2abi1CAMineralocorticoid receptor/0.459
2c92TP66,7-dimethyl-8-ribityllumazine synthase2.5.1.780.459
2e1zB4PPropionate kinase/0.459
2vteIK4UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.459
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.459
3c3xNAPEugenol synthase 11.1.1.3180.459
3hxeBD8Geranylgeranyl transferase type-2 subunit beta2.5.1.600.459
3ln1CELProstaglandin G/H synthase 21.14.99.10.459
3n0hTOPDihydrofolate reductase1.5.1.30.459
3njoP2MAbscisic acid receptor PYR1/0.459
3qpnPFKcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.459
3vn2TLSPeroxisome proliferator-activated receptor gamma/0.459
3zlmANPAdenosine monophosphate-protein transferase NmFic2.7.7.n10.459
4bb5HD2Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.459
4eilFOLBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.459
4y9xUPGGlucosyl-3-phosphoglycerate synthase2.4.1.2660.459
1al8DHPPeroxisomal (S)-2-hydroxy-acid oxidase1.1.3.150.458
1e79ADPATP synthase subunit alpha, mitochondrial/0.458
1e79ADPATP synthase subunit beta, mitochondrial3.6.3.140.458
1fgiSU1Fibroblast growth factor receptor 1/0.458
1itzTPPTransketolase, chloroplastic2.2.1.10.458
1kfcIPLTryptophan synthase alpha chain/0.458
1kwcBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.458
1o9bNAIQuinate/shikimate dehydrogenase/0.458
1p0hACOMycothiol acetyltransferase2.3.1.1890.458
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.458
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.458
1ygkRRCPyridoxal kinase2.7.1.350.458
1ykdCMPAdenylate cyclase/0.458
2c27ACOMycothiol acetyltransferase2.3.1.1890.458
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.458
2ph5NADHomospermidine synthase/0.458
3dgeADPSensor histidine kinase/0.458
3g72A6TRenin3.4.23.150.458
3gxoMQAMitomycin biosynthesis 6-O-methyltransferase/0.458
3o3nIRC(R)-2-hydroxyisocaproyl-CoA dehydratase alpha subunit/0.458
3vt5YI2Vitamin D3 receptor/0.458
4a86H35Major pollen allergen Bet v 1-A/0.458
4b10NHWGlycylpeptide N-tetradecanoyltransferase/0.458
4cdmFO1Deoxyribodipyrimidine photolyase/0.458
4ek1CAMCamphor 5-monooxygenase1.14.15.10.458
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.458
4isk1JYThymidylate synthase/0.458
4j3mAJ8Tankyrase-22.4.2.300.458
4jq4IMNAldo-keto reductase family 1 member C2/0.458
1dhjMTXDihydrofolate reductase1.5.1.30.457
1ek2CDUBifunctional epoxide hydrolase 2/0.457
1juvNDPDihydrofolate reductase1.5.1.30.457
1k9sFM2Purine nucleoside phosphorylase DeoD-type/0.457
1q9mROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.457
1t3zCAOFormyl-CoA:oxalate CoA-transferase/0.457
1xu9CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.457
1zgyBRLPeroxisome proliferator-activated receptor gamma/0.457
2b01TUDPhospholipase A2, major isoenzyme3.1.1.40.457
2bjfDXCCholoylglycine hydrolase3.5.1.240.457
2ftoCB3Thymidylate synthase/0.457
2ghtSER_PRO_THR_PRO_SEPCarboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 13.1.3.160.457
2jb4A14Isopenicillin N synthase1.21.3.10.457
2qd3CHDFerrochelatase, mitochondrial4.99.1.10.457
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.457
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.457
3rueNADUDP-N-acetylglucosamine 4-epimerase/0.457
3v94WYQPhosphodiesterase/0.457
4da7AC2Purine nucleoside phosphorylase DeoD-type2.4.2.10.457
4dwvPFBAlcohol dehydrogenase E chain1.1.1.10.457
4e0iFADMitochondrial FAD-linked sulfhydryl oxidase ERV11.8.3.20.457
4fgh0U6Dihydrofolate reductase1.5.1.30.457
4gkh0J9Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.457
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.457
4i6h1C8Serine/threonine-protein kinase PLK22.7.11.210.457
4l0t1V0Tankyrase-22.4.2.300.457
4p6wMOFGlucocorticoid receptor/0.457
4ugaQ05Nitric oxide synthase oxygenase1.14.13.1650.457
4x7vMIVMycinamicin III 3''-O-methyltransferase2.1.1.2370.457
1ddsMTXDihydrofolate reductase1.5.1.30.456
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.456
1m9k7NINitric oxide synthase, endothelial1.14.13.390.456
1pr0NOSPurine nucleoside phosphorylase DeoD-type/0.456
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.456
1q5dEPBEpothilone C/D epoxidase1.140.456
1rf7DHFDihydrofolate reductase1.5.1.30.456
1z4uPH9Polyprotein/0.456
2bifANP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 42.7.1.1050.456
2g8yNADHydroxycarboxylate dehydrogenase B/0.456
2gpvOHTEstrogen-related receptor gamma/0.456
2oz57XYUncharacterized protein/0.456
2vezACOGlucosamine 6-phosphate acetyltransferase, putative/0.456
2vrbNAPTriphenylmethane reductase/0.456
2xvv9DNSerum albumin/0.456
3aivHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic3.2.1.1820.456
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.456
3hf6LX0Tryptophan 5-hydroxylase 11.14.16.40.456
3n39FMNProtein NrdI/0.456
3ol5SAWCamphor 5-monooxygenase1.14.15.10.456
3qgzADNHistidine triad nucleotide-binding protein 130.456
3sgv2BJDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.456
3t1a5MAGag-Pol polyprotein2.7.7.490.456
3tdaPN0Cytochrome P450 2D6/0.456
3vt9YI4Vitamin D3 receptor/0.456
4bfxZVXPantothenate kinase2.7.1.330.456
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.456
4dreNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.456
4equG6ISerine/threonine-protein kinase 102.7.11.10.456
4hw219HInduced myeloid leukemia cell differentiation protein Mcl-1/0.456
4ia2BIVVitamin D3 receptor A/0.456
4jq3NAPAldo-keto reductase family 1 member C2/0.456
4krs1SXTankyrase-12.4.2.300.456
4li71XPTankyrase-12.4.2.300.456
4n1gCEIObelin/0.456
4nbjD3YD-tyrosyl-tRNA(Tyr) deacylase/0.456
4u07ATPAdenosine monophosphate-protein transferase FICD2.7.7.n10.456
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.456
5c93ACPTwo-component system histidine protein kinase/0.456
5cdsPFBAlcohol dehydrogenase E chain1.1.1.10.456
5epoTUD7-alpha-hydroxysteroid deydrogenase/0.456
1fm4DXCMajor pollen allergen Bet v 1-L/0.455
1kyzFERCaffeic acid 3-O-methyltransferase2.1.1.680.455
1rzuADPGlycogen synthase 12.4.1.210.455
1u1d181Uridine phosphorylase2.4.2.30.455
1w7kADPDihydrofolate synthase/folylpolyglutamate synthase6.3.2.120.455
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.455
1zknIBMcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.455
1zq5E04Aldo-keto reductase family 1 member C3/0.455
2cvzNDP3-hydroxyisobutyrate dehydrogenase/0.455
2dhfDZFDihydrofolate reductase1.5.1.30.455
2feuCAMCamphor 5-monooxygenase1.14.15.10.455
2hcdBIVVitamin D3 receptor A/0.455
2o8h227cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.455
2w6pOA4Biotin carboxylase6.3.4.140.455
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.455
2y035FWBeta-1 adrenergic receptor/0.455
3a7dFBNCatechol O-methyltransferase2.1.1.60.455
3bxxQUEDihydroflavonol 4-reductase1.1.1.2190.455
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.455
3dhcCYKN-acyl homoserine lactonase AiiA3.1.1.810.455
3hbfMYCFlavonoid 3-O-glucosyltransferase2.4.10.455
3mwuBK3Calmodulin-domain protein kinase 1, putative/0.455
3siiA1RUncharacterized protein/0.455
4bueJQFTankyrase-22.4.2.300.455
4c0bATPmRNA cleavage and polyadenylation factor CLP1/0.455
4da6GA2Purine nucleoside phosphorylase DeoD-type2.4.2.10.455
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.455
4fgcPQ0NADPH-dependent 7-cyano-7-deazaguanine reductase1.7.1.130.455
4l341VGTankyrase-22.4.2.300.455
4phlPILPhosphodiesterase/0.455
4v010LIFibroblast growth factor receptor 1 (Fms-related tyrosine kinase 2, Pfeiffer syndrome), isoform CRA_b/0.455
4yp6NAPNicotinamide-nucleotide adenylyltransferase2.7.7.10.455
1jdzFMBPurine nucleoside phosphorylase/0.454
1kzjCB3Thymidylate synthase/0.454
1oc1ASVIsopenicillin N synthase1.21.3.10.454
1rdt570Peroxisome proliferator-activated receptor gamma/0.454
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.454
2ath3EAPeroxisome proliferator-activated receptor gamma/0.454
2clmF6FTryptophan synthase alpha chain/0.454
2f0y3MNProtein farnesyltransferase subunit beta2.5.1.580.454
2geuCOKPantothenate kinase2.7.1.330.454
2harOCCVitamin D3 receptor/0.454
2q8sL92Peroxisome proliferator-activated receptor gamma/0.454
2w98P1ZProstaglandin reductase 21.3.1.480.454
2xweAMFGlucosylceramidase3.2.1.450.454
2yhuWHFPteridine reductase/0.454
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.454
3b9oFMNAlkane monoxygenase/0.454
3bgxMEFThymidylate synthase/0.454
3vjcZGASqualene synthase2.5.1.210.454
3wixLC3Induced myeloid leukemia cell differentiation protein Mcl-1/0.454
4bus32FTankyrase-22.4.2.300.454
4c2z646Glycylpeptide N-tetradecanoyltransferase 1/0.454
4erf0R3E3 ubiquitin-protein ligase Mdm26.3.20.454
4fam0SZAldo-keto reductase family 1 member C3/0.454
4h6rFDAProline dehydrogenase/0.454
4irnFADAnaB/0.454
4rriA3TProbable threonine--tRNA ligase 26.1.1.30.454
4twnB96Ephrin type-A receptor 32.7.10.10.454
4x28FDAAcyl-CoA dehydrogenase FadE26/0.454
4x28FDAAcyl-CoA dehydrogenase FadE27/0.454
5jtbZMAAdenosine receptor A2a/0.454
1dnpMHFDeoxyribodipyrimidine photo-lyase4.1.99.30.453
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.453
1gs4ZK5Androgen receptor/0.453
1k9sFM1Purine nucleoside phosphorylase DeoD-type/0.453
1kmsLIHDihydrofolate reductase1.5.1.30.453
1nueGDPNucleoside diphosphate kinase B2.7.4.60.453
1rc4DDFDihydrofolate reductase1.5.1.30.453
1rt1MKCGag-Pol polyprotein2.7.7.490.453
1rx5DDFDihydrofolate reductase1.5.1.30.453
1s3wTQTDihydrofolate reductase1.5.1.30.453
1tkaN3TTransketolase 12.2.1.10.453
1towCRZFatty acid-binding protein, adipocyte/0.453
1xddAAYIntegrin alpha-L/0.453
2a9z26AAdenosine kinase2.7.1.200.453
2aclREARetinoic acid receptor RXR-alpha/0.453
2amb17HAndrogen receptor/0.453
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.453
2hw2RFPRifampin ADP-ribosyl transferase/0.453
2vbdV10Isopenicillin N synthase1.21.3.10.453
2xdaJPS3-dehydroquinate dehydratase4.2.1.100.453
2z3uCRRCytochrome P450/0.453
2zbaZBATrichothecene 3-O-acetyltransferase/0.453
3gkiCLRNiemann-Pick C1 protein/0.453
3ielU5PRibonuclease TTHA02523.10.453
3lfcZ86Mitogen-activated protein kinase 14/0.453
3s3vTOPDihydrofolate reductase1.5.1.30.453
3sgtP09Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)/0.453
4e2bFMNDehydrogenase/0.453
4fqsLYAThymidylate synthase ThyA/0.453
4g210VPVitamin D3 receptor A/0.453
4i9z5BAcGMP-specific 3',5'-cyclic phosphodiesterase/0.453
4iah1DXAlr2278 protein/0.453
4kdrSAHUbiquinone biosynthesis O-methyltransferase/0.453
4oplFDAConserved Archaeal protein/0.453
4pl0ANPMicrocin-J25 export ATP-binding/permease protein McjD/0.453
4q71FADBifunctional protein PutA/0.453
4qa2SHHHistone deacetylase 83.5.1.980.453
5d7q4I5NAD-dependent protein deacetylase sirtuin-23.5.10.453
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.453
5k2cZMAAdenosine receptor A2a/0.453
3emlZMAAdenosine receptor A2a/0.453
1c1c612Gag-Pol polyprotein2.7.7.490.452
1vrqFONSubunit alpha of sarocosine oxidase/0.452
2f3815MAldo-keto reductase family 1 member C3/0.452
2h447CAcGMP-specific 3',5'-cyclic phosphodiesterase/0.452
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.452
2pb6SAHDiphthine synthase/0.452
2q59240Peroxisome proliferator-activated receptor gamma/0.452
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1840.452
3d3p20AcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.452
3dfrMTXDihydrofolate reductase1.5.1.30.452
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.452
3id8MRKGlucokinase2.7.1.20.452
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
3phcIM5Purine nucleoside phosphorylase/0.452
3qls55VDihydrofolate reductase1.5.1.30.452
3r6c17NAnthranilate phosphoribosyltransferase/0.452
3sh25DRDihydrofolate reductase1.5.1.30.452
3tm5SFGUncharacterized protein/0.452
3vey0H5Glucokinase2.7.1.20.452
4a0sCO8Octenoyl-CoA reductase/carboxylase/0.452
4bfvZVVPantothenate kinase2.7.1.330.452
4hlh20DTankyrase-22.4.2.300.452
4q0kGA3Phytohormone-binding protein/0.452
4tmcFMNOld yellow enzyme/0.452
3d4sTIMBeta-2 adrenergic receptor/0.452
1ezfIN0Squalene synthase2.5.1.210.451
1fxuGU7Purine nucleoside phosphorylase2.4.2.10.451
1qv0CZHObelin/0.451
1txtCAAHMG-CoA synthase/0.451
1udtVIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.451
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.451
2c9dPHR6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.451
2cy0NAPShikimate dehydrogenase (NADP(+))/0.451
2hvcLGDAndrogen receptor/0.451
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.451
2ij7TPFMycocyclosin synthase1.14.21.90.451
2iltNN1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.451
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.451
2j3qTFLAcetylcholinesterase3.1.1.70.451
2obxINI6,7-dimethyl-8-ribityllumazine synthase 22.5.1.780.451
2ovvPFHcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.451
2pdlTOLAldose reductase1.1.1.210.451
2qimZEAClass 10 plant pathogenesis-related protein/0.451
2rgxAP5Adenylate kinase/0.451
2wd4TBVAscorbate peroxidase/0.451
2xb8XNW3-dehydroquinate dehydratase4.2.1.100.451
2znoS44Peroxisome proliferator-activated receptor gamma/0.451
3c35KAIGlutamate receptor ionotropic, kainate 1/0.451
3ctj320Hepatocyte growth factor receptor2.7.10.10.451
3cv9VDXVitamin D3 dihydroxylase/0.451
3eksCY9Actin-5C/0.451
3inwJZBHeat shock protein HSP 90-alpha/0.451
3p6oETGCamphor 5-monooxygenase1.14.15.10.451
3ssmSAHMycinamicin VI 2''-O-methyltransferase/0.451
3wd9QPCcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.451
4buuF38Tankyrase-22.4.2.300.451
4c1fX8ZMetallo-beta-lactamase type 2/0.451
4hknLU2Tankyrase-22.4.2.300.451
4imuH4BNitric oxide synthase, brain1.14.13.390.451
4jln18VDeoxycytidine kinase2.7.1.740.451
4l2f1V3Tankyrase-22.4.2.300.451
4oznATPAmmonium transporter/0.451
4qa1B3NHistone deacetylase 83.5.1.980.451
4tnxDGTDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.451
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.451
5k2bZMAAdenosine receptor A2a/0.451
1i7gAZ2Peroxisome proliferator-activated receptor alpha/0.450
1ngsTPPTransketolase 12.2.1.10.450
1pf7IMHPurine nucleoside phosphorylase2.4.2.10.450
1rd4L08Integrin alpha-L/0.450
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
1vf2GTXGlutathione S-transferase 32.5.1.180.450
1ygjRMCPyridoxal kinase2.7.1.350.450
1zgbA1EAcetylcholinesterase3.1.1.70.450
2aclL05Oxysterols receptor LXR-alpha/0.450
2dw4FADLysine-specific histone demethylase 1A10.450
2ed3SAHDiphthine synthase/0.450
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
2g263LGRenin3.4.23.150.450
2jlcTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.450
2psjCEIRenilla-luciferin 2-monooxygenase1.13.12.50.450
2vssACOHydroxycinnamoyl-CoA hydratase-lyase4.1.2.410.450
2x2rADPKinesin-like protein KIF11/0.450
2ywlFADThioredoxin reductase related protein/0.450
2znq401Peroxisome proliferator-activated receptor delta/0.450
3fowIMHPurine nucleoside phosphorylase/0.450
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.450
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.450
3nwlNDPCatalase1.11.1.60.450
3qm4PN0Cytochrome P450 2D6/0.450
3vrvYSDVitamin D3 receptor/0.450
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.450
3zkuHCVIsopenicillin N synthase1.21.3.10.450
4b5oACOAlpha-tubulin N-acetyltransferase 1/0.450
4g34924Eukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.450
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.450
4ips1G4Mycocyclosin synthase1.14.21.90.450
4m8e29VRetinoic acid receptor RXR-alpha/0.450
4n4v2GYTankyrase-12.4.2.300.450
4zqmXMPInosine-5'-monophosphate dehydrogenase/0.450
5e8jSAHmRNA cap guanine-N7 methyltransferase2.1.1.560.450
1cbqRE9Cellular retinoic acid-binding protein 2/0.449
1dgbNDPCatalase1.11.1.60.449
1i59ADPChemotaxis protein CheA2.7.13.30.449
1nbmADPATP synthase subunit beta, mitochondrial3.6.3.140.449
1osvCHCBile acid receptor/0.449
1ra3NAPDihydrofolate reductase1.5.1.30.449
2bbqPFGThymidylate synthase/0.449
2bdyUNBProthrombin3.4.21.50.449
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.449
2bzsCB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.449
2gs9SAHUncharacterized protein/0.449
2hamC33Vitamin D3 receptor/0.449
2p1u4TNRetinoic acid receptor RXR-alpha/0.449
2rcyNAPPyrroline-5-carboxylate reductase/0.449
2vn0TDZCytochrome P450 2C8/0.449
3csdEMOPutative ketoacyl reductase1.3.10.449
3f47I2C5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.449
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
3fkoFKOMitogen-activated protein kinase 14/0.449
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.449
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.449
3tubFPUTyrosine-protein kinase SYK2.7.10.20.449
3x065GPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1490.449
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.449
4boeCLRJapanin/0.449
4brdANPEctonucleoside triphosphate diphosphohydrolase I/0.449
4c49HCYCorticosteroid-binding globulin/0.449
4d0l093Phosphatidylinositol 4-kinase beta2.7.1.670.449
4g1d0VKVitamin D3 receptor A/0.449
4htx19FcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.449
4ict1EDMycocyclosin synthase1.14.21.90.449
4jtqFLPAldo-keto reductase family 1 member C2/0.449
4pnmNU1Tankyrase-22.4.2.300.449
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.449
4z44FADFlavin-dependent tryptophan halogenase PrnA1.14.19.90.449
5iu4ZMAAdenosine receptor A2a/0.449
1cjvFOKAdenylate cyclase type 2/0.448
1cjvFOKAdenylate cyclase type 5/0.448
1j3kWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.448
1kt6RTLRetinol-binding protein 4/0.448
1mznBM6Retinoic acid receptor RXR-alpha/0.448
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.448
1w19T1P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.448
1x1aSAMC-20 methyltransferase/0.448
1y0s331Peroxisome proliferator-activated receptor delta/0.448
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.448
2ahrNAPPyrroline-5-carboxylate reductase/0.448
2e8sSAHDiphthine synthase/0.448
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.448
2hxzH7JCathepsin S3.4.22.270.448
2oiqSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.448
2qc8ADPGlutamine synthetase6.3.1.20.448
2qw8NAPEugenol synthase 11.1.1.3180.448
2tplHPPTyrosine phenol-lyase4.1.99.20.448
2v58LZJBiotin carboxylase6.3.4.140.448
2x9dITCTetracycline repressor protein class D/0.448
2zynBCDPeriplasmic binding protein/0.448
3eg5GNPCell division control protein 42 homolog/0.448
3ekuCY9Actin-5C/0.448
3fr4F8AFatty acid-binding protein, adipocyte/0.448
3gi2GHWDihydrofolate reductase1.5.1.30.448
3ndjJHZMethyltransferase/0.448
3nmpPYVAbscisic acid receptor PYL2/0.448
3nw9637Catechol O-methyltransferase2.1.1.60.448
3o4rNAPDehydrogenase/reductase SDR family member 41.1.1.1840.448
3ou6SAMSAM-dependent methyltransferase/0.448
3p0pNNFTankyrase-22.4.2.300.448
3ssoSAHMycinamicin VI 2''-O-methyltransferase/0.448
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.448
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.448
4a87NARMajor pollen allergen Bet v 1-A/0.448
4as94QSATP-dependent molecular chaperone HSP82/0.448
4b2gV1NUncharacterized protein/0.448
4bc7FADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.448
4bfrJ82Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform2.7.1.1530.448
4ey20RMMetallo-beta-lactamase type 2/0.448
4ia1BIVVitamin D3 receptor A/0.448
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.448
4l10A63Tankyrase-22.4.2.300.448
4l33F70Tankyrase-22.4.2.300.448
4myq19TcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.448
4tkg09LTankyrase-22.4.2.300.448
4x5iFOLDihydrofolate reductase1.5.1.30.448
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA23.6.30.448
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA1/0.448
5aku29FTankyrase-22.4.2.300.448
5d1bTSNHistone deacetylase 83.5.1.980.448
1dg5TOPDihydrofolate reductase1.5.1.30.447
1fx9MJIPhospholipase A2, major isoenzyme3.1.1.40.447
1odcA8BAcetylcholinesterase3.1.1.70.447
1p33MTXPteridine reductase 11.5.1.330.447
2ejzSAHDiphthine synthase/0.447
2fmn4HF5,10-methylenetetrahydrofolate reductase1.5.1.200.447
2gilGTPRas-related protein Rab-6A/0.447
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
3fktSIIBeta-secretase 13.4.23.460.447
3fwiCAMCamphor 5-monooxygenase1.14.15.10.447
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.447
3i68J4ZDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.447
3ihgVAKAklavinone 12-hydroxylase RdmE/0.447
3jwcEKBDihydrofolate reductase/0.447
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
3pgtGBXGlutathione S-transferase P2.5.1.180.447
3phiNDPShikimate dehydrogenase (NADP(+))/0.447
3u9eCOALmo1369 protein/0.447
3w5rLOAVitamin D3 receptor/0.447
3wv9FEGHmd co-occurring protein HcgE/0.447
4a31MYAGlycylpeptide N-tetradecanoyltransferase/0.447
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.447
4blcNDPCatalase1.11.1.60.447
4cax646Glycylpeptide N-tetradecanoyltransferase2.3.1.970.447
4e37NDPCatalase1.11.1.60.447
4f0rMTA5-methylthioadenosine/S-adenosylhomocysteine deaminase/0.447
4g3jVNTLanosterol 14-alpha-demethylase/0.447
4g47TZFMycocyclosin synthase1.14.21.90.447
4kc1WS1Histo-blood group ABO system transferase/0.447
4nfhPFBAlcohol dehydrogenase E chain1.1.1.10.447
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.447
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.447
1aquESTEstrogen sulfotransferase, testis isoform2.8.2.40.446
1b2lNDCAlcohol dehydrogenase1.1.1.10.446
1bnnAL1Carbonic anhydrase 24.2.1.10.446
1cqp803Integrin alpha-L/0.446
1rf9DBRCamphor 5-monooxygenase1.14.15.10.446
1rkpIBMcGMP-specific 3',5'-cyclic phosphodiesterase/0.446
1rzy5ASHistidine triad nucleotide-binding protein 130.446
1tdrMTXDihydrofolate reductase1.5.1.30.446
1xngDNDNH(3)-dependent NAD(+) synthetase6.3.1.50.446
2du8FADD-amino-acid oxidase1.4.3.30.446
2e9dB76Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.446
2j9lATPH(+)/Cl(-) exchange transporter 5/0.446
2ojg19AMitogen-activated protein kinase 12.7.11.240.446
2rewREWPeroxisome proliferator-activated receptor alpha/0.446
2zb45OPProstaglandin reductase 21.3.1.480.446
2zsdCOAPantothenate kinase2.7.1.330.446
3ar6TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.446
3bqdDAYGlucocorticoid receptor/0.446
3c72CX1Geranylgeranyl transferase type-2 subunit beta2.5.1.600.446
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3e92G6AMitogen-activated protein kinase 14/0.446
3gf4U5PUDP-galactopyranose mutase5.4.99.90.446
3i0pNADMalate dehydrogenase, putative/0.446
3i6rJ5ZDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.446
3oquA8SAbscisic acid receptor PYL9/0.446
3qp8HL0Transcriptional activator, LuxR/UhpA family of regulators/0.446
3qpoPFRcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.446
3u9y09LTankyrase-22.4.2.300.446
3ukoNADAlcohol dehydrogenase class-3/0.446
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.446
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.446
4avwG18Tankyrase-22.4.2.300.446
4fhi0S4Vitamin D3 receptor A/0.446
4g2rH1LProbable propionyl-CoA carboxylase beta chain 66.4.1.30.446
4g8zTOPDihydrofolate reductase1.5.1.30.446
4gi2NAPCrotonyl-CoA carboxylase/reductase/0.446
4jlk1NODeoxycytidine kinase2.7.1.740.446
4kwhNAPReductase homolog/0.446
4mlp2CXCryptochrome-2/0.446
4rrbA3TProbable threonine--tRNA ligase 26.1.1.30.446
4x5jFOLDihydrofolate reductase1.5.1.30.446
4xiwAZMCarbonic anhydrase, alpha type/0.446
4zowCLMMultidrug transporter MdfA/0.446
5ag5MYAGlycylpeptide N-tetradecanoyltransferase/0.446
5bsfNADPyrroline-5-carboxylate reductase/0.446
5iua6DXAdenosine receptor A2a/0.446
1ah3TOLAldose reductase1.1.1.210.445
1dd6MCIMetallo-beta-lactamase type 2/0.445
1disBDMDihydrofolate reductase1.5.1.30.445
1frbZSTAldose reductase-related protein 2/0.445
1krrACOGalactoside O-acetyltransferase2.3.1.180.445
1m9hNAD2,5-diketo-D-gluconic acid reductase A1.1.1.3460.445
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.445
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.445
1rxjBNIStreptavidin/0.445
1tg56454-hydroxyphenylpyruvate dioxygenase1.13.11.270.445
1u1f183Uridine phosphorylase2.4.2.30.445
1xuzMMNCapsule biosynthesis protein/0.445
1yzqGNPRas-related protein Rab-6A/0.445
2a9y26AAdenosine kinase2.7.1.200.445
2anb5GPGuanylate kinase2.7.4.80.445
2eeqSAHDiphthine synthase/0.445
2x06NADL-sulfolactate dehydrogenase/0.445
2yatEEUEstrogen receptor/0.445
2yvwEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.445
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.445
3gobHXXDdmC/0.445
3h86AP5Adenylate kinase/0.445
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.445
3nx4NAPPutative oxidoreductase/0.445
3nz2ACOHexapeptide-repeat containing-acetyltransferase/0.445
3oqkS52Renin3.4.23.150.445
3qlxQLRUncharacterized protein/0.445
3t0kDCQSulfide-quinone reductase/0.445
3tfjTHGDimethylsulfonioproprionate demethylase DmdA2.1.1.2690.445
3w6hAZMCarbonic anhydrase 14.2.1.10.445
4at0FADPossible succinate dehydrogenase/0.445
4feu537Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.445
4h4m494Gag-Pol polyprotein2.7.7.490.445
4h9814QUncharacterized protein/0.445
4isg1FYGlucokinase2.7.1.20.445
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.445
4xe606UDihydrofolate reductase1.5.1.30.445
5ej8TD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.445
5hwpCOAHydroxymethylglutaryl-CoA synthase/0.445
5iubCLRAdenosine receptor A2a/0.445
5d5bCAUBeta-2 adrenergic receptor/0.445
1bx9GLY_GGL_FOEGlutathione S-transferase F22.5.1.180.444
1cbrREACellular retinoic acid-binding protein 1/0.444
1db1VDXVitamin D3 receptor/0.444
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1h74ADPHomoserine kinase2.7.1.390.444
1hk3T44Serum albumin/0.444
1nw4IMHPurine nucleoside phosphorylase/0.444
1ot7CHCBile acid receptor/0.444
1s0zEB1Vitamin D3 receptor/0.444
1t4cCOAFormyl-CoA:oxalate CoA-transferase/0.444
1u1jC2F5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 12.1.1.140.444
1zw9H64ATP-dependent molecular chaperone HSP82/0.444
2bf4NAPNADPH--cytochrome P450 reductase/0.444
2e98B29Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.444
2igxA1TPlasmepsin 2/0.444
2in6839Wee1-like protein kinase2.7.10.20.444
2jj2ADPATP synthase subunit alpha, mitochondrial/0.444
2jj2ADPATP synthase subunit beta, mitochondrial3.6.3.140.444
2oyuIMSProstaglandin G/H synthase 11.14.99.10.444
2rkuR78Serine/threonine-protein kinase PLK12.7.11.210.444
2xlpFADPutative flavin-containing monooxygenase/0.444
3ey4352Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
3f82353Hepatocyte growth factor receptor2.7.10.10.444
3g5qFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.444
3gb4D3MDdmC/0.444
3gmd2M3Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
3h1vTK1Glucokinase2.7.1.20.444
3hf8ML0Tryptophan 5-hydroxylase 11.14.16.40.444
3nxyD2HDihydrofolate reductase1.5.1.30.444
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
3p3c3P3UDP-3-O-acyl-N-acetylglucosamine deacetylase/0.444
3r6pA8SAbscisic acid receptor PYL10/0.444
3thrC2FGlycine N-methyltransferase2.1.1.200.444
3wavDWVEctonucleotide pyrophosphatase/phosphodiesterase family member 23.1.4.390.444
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.444
4bftZVTPantothenate kinase2.7.1.330.444
4bfwZVWPantothenate kinase2.7.1.330.444
4f650S9Fibroblast growth factor receptor 1/0.444
4g48PZBMycocyclosin synthase1.14.21.90.444
4giu636Anthranilate phosphoribosyltransferase/0.444
4hfr14MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
4j6bPLOCytochrome P450 monooxygenase/0.444
4jvr1MTE3 ubiquitin-protein ligase Mdm26.3.20.444
4l0i1UWTankyrase-22.4.2.300.444
4m6l21VDihydrofolate reductase1.5.1.30.444
4n4t2GVTankyrase-12.4.2.300.444
4rrlA3SProbable threonine--tRNA ligase 26.1.1.30.444
4stdBFSScytalone dehydratase4.2.1.940.444
4tl7ATPCircadian clock protein kinase KaiC2.7.11.10.444
5dcyNAPIridoid synthase1.3.1.990.444
5iu86DZAdenosine receptor A2a/0.444
1cjcFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.443
1gpdNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.443
1icpFMN12-oxophytodienoate reductase 11.3.1.420.443
1ja0FMNNADPH--cytochrome P450 reductase/0.443
1kqoDNDNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.443
1kt7RTLRetinol-binding protein 4/0.443
1kvrNADUDP-glucose 4-epimerase5.1.3.20.443
1mvtDTMDihydrofolate reductase1.5.1.30.443
1s64778Geranylgeranyl transferase type-1 subunit beta2.5.1.590.443
1trgCB3Thymidylate synthase/0.443
1yvfPH7Polyprotein/0.443
1yw1FMNPutative monooxygenase MoxC1.140.443
2bfrADP[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.443
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.443
2c7gFADNADPH-ferredoxin reductase FprA1.18.1.20.443
2cbqTH2Neocarzinostatin/0.443
2cl5BIECatechol O-methyltransferase2.1.1.60.443
2fxuBIDActin, alpha skeletal muscle/0.443
2hbhXE4Vitamin D3 receptor A/0.443
2hl2SSAThreonine--tRNA ligase6.1.1.30.443
2vd0D27Hematopoietic prostaglandin D synthase/0.443
2xb9XNW3-dehydroquinate dehydratase4.2.1.100.443
2yj5ATPCopper-transporting ATPase/0.443
2znpK55Peroxisome proliferator-activated receptor delta/0.443
3dauMTXDihydrofolate reductase1.5.1.30.443
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3fy8XCFDihydrofolate reductase1.5.1.30.443
3fznD7KBenzoylformate decarboxylase4.1.1.70.443
3gc8B45Mitogen-activated protein kinase 112.7.11.240.443
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.443
3lm4HPXCatechol 2,3-dioxygenase/0.443
3ncrADPNitrogen regulatory protein P-II (GlnB-2)/0.443
3p6pA6BCamphor 5-monooxygenase1.14.15.10.443
3pz23PZGeranylgeranyl transferase type-2 subunit beta2.5.1.600.443
3qgf46FGenome polyprotein2.7.7.480.443
3uawADNPurine nucleoside phosphorylase DeoD-type/0.443
3uk6ADPRuvB-like 23.6.4.120.443
3vhmNPKAvidin/0.443
3vt8YI3Vitamin D3 receptor/0.443
3w5p4OAVitamin D3 receptor/0.443
4ao4PLKBeta-transaminase/0.443
4bb2STRCorticosteroid-binding globulin/0.443
4cgpMYAGlycylpeptide N-tetradecanoyltransferase/0.443
4dijBLFE3 ubiquitin-protein ligase Mdm26.3.20.443
4dpuAGSMevalonate diphosphate decarboxylase/0.443
4fcb0T7cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
4h4o506Gag-Pol polyprotein2.7.7.490.443
4h8004TAldehyde dehydrogenase, dimeric NADP-preferring/0.443
4j491J1Uncharacterized protein/0.443
4kwcSAHMethyltransferase domain family/0.443
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
4lrrCF9Thymidylate synthase/0.443
4ttjFMCPurine nucleoside phosphorylase DeoD-type/0.443
1aqxGTDGlutathione S-transferase P2.5.1.180.442
1be4PCGNucleoside diphosphate kinase A 22.7.4.60.442
1df7MTXDihydrofolate reductase1.5.1.30.442
1pq944BOxysterols receptor LXR-beta/0.442
1qorNDPQuinone oxidoreductase 1/0.442
1rjkVDZVitamin D3 receptor/0.442
1t87CAMCamphor 5-monooxygenase1.14.15.10.442
1uyhPU0Heat shock protein HSP 90-alpha/0.442
1uykPUXHeat shock protein HSP 90-alpha/0.442
1w19T5P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.442
1z7yAA5Cysteine synthase 12.5.1.470.442
2b0qADPAminoglycoside 3'-phosphotransferase2.7.1.950.442
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.442
2cy2ACOProbable acetyltransferase/0.442
2fhjMFNFormylmethanofuran--tetrahydromethanopterin formyltransferase2.3.1.1010.442
2fjm073Tyrosine-protein phosphatase non-receptor type 13.1.3.480.442
2h42VIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.442
2jdcCAOProbable acetyltransferase/0.442
2jl1NAPTriphenylmethane reductase/0.442
2nn7M29Carbonic anhydrase 14.2.1.10.442
2oaxSNLMineralocorticoid receptor/0.442
2og81N8Tyrosine-protein kinase Lck2.7.10.20.442
2oh4GIGVascular endothelial growth factor receptor 22.7.10.10.442
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
3af1GDPPantothenate kinase2.7.1.330.442
3dyaPZLGag-Pol polyprotein2.7.7.490.442
3fzwEQUSteroid Delta-isomerase5.3.3.10.442
3gw9VNILanosterol 14-alpha-demethylase/0.442
3htjETEbrA repressor/0.442
3ixp834Ecdysone receptor/0.442
3jqpA2PFerredoxin--NADP reductase, apicoplast/0.442
3mbgFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.442
3mg3ECHOrange carotenoid-binding protein/0.442
3n87N873-dehydroquinate dehydratase4.2.1.100.442
3oadLPORenin3.4.23.150.442
3vruYS3Vitamin D3 receptor/0.442
3zuyTCHTransporter/0.442
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
4awo99BHeat shock protein HSP 90-alpha/0.442
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.442
4fk8FADFerredoxin--NADP reductase/0.442
4fnyI3KALK tyrosine kinase receptor2.7.10.10.442
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
4h9614QDihydrofolate reductase1.5.1.30.442
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.442
4jq3ZOMAldo-keto reductase family 1 member C2/0.442
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.442
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.442
4o281QSNicotinamide phosphoribosyltransferase2.4.2.120.442
4o71CPBBromodomain-containing protein 4/0.442
4rnvFMNNADPH dehydrogenase 11.6.99.10.442
4xba5GPAprataxin-like protein30.442
5bn3ADPV-type ATP synthase alpha chain/0.442
5bn3ADPNEQ263/0.442
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.442
1dgfNDPCatalase1.11.1.60.441
1dr4HBIDihydrofolate reductase1.5.1.30.441
1gqyACPUDP-N-acetylmuramate--L-alanine ligase6.3.2.80.441
1ia3TQ5Dihydrofolate reductase1.5.1.30.441
1jqiCAAShort-chain specific acyl-CoA dehydrogenase, mitochondrial/0.441
1knuYPAPeroxisome proliferator-activated receptor gamma/0.441
1nsgRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.441
1nsgRADSerine/threonine-protein kinase mTOR2.7.11.10.441
1re7FOLDihydrofolate reductase1.5.1.30.441
1rk3VDXVitamin D3 receptor/0.441
1rpwDIDHTH-type transcriptional regulator QacR/0.441
1s9dAFBCytohesin-2/0.441
1s9dAFBADP-ribosylation factor 1/0.441
1sweBTNStreptavidin/0.441
1synF89Thymidylate synthase/0.441
1thz326Bifunctional purine biosynthesis protein PURH2.1.2.30.441
1x8lOXRRetinol dehydratase/0.441
2bf7HBIPteridine reductase 11.5.1.330.441
2d0kFOLDihydrofolate reductase1.5.1.30.441
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.441
2ejjSAHDiphthine synthase/0.441
2ekpNAD2-deoxy-D-gluconate 3-dehydrogenase/0.441
2f99AKVAklanonic acid methyl ester cyclase AcmA5.5.1.230.441
2igyA2TPlasmepsin 2/0.441
2npxNADNADH peroxidase1.11.1.10.441
2om9AJAPeroxisome proliferator-activated receptor gamma/0.441
2oyeIM8Prostaglandin G/H synthase 11.14.99.10.441
2q66ATPPoly(A) polymerase2.7.7.190.441
2vz0D64Pteridine reductase/0.441
2w9gTOPDihydrofolate reductase1.5.1.30.441
2wdzNADGalactitol dehydrogenase/0.441
2xkdT3MSerine/threonine-protein kinase Nek22.7.11.10.441
2zi53L1Deoxycytidine kinase2.7.1.740.441
3aw9NADNAD-dependent epimerase/dehydratase/0.441
3frfXCFDihydrofolate reductase1.5.1.30.441
3gl2D3MDdmC/0.441
3hgsFMN12-oxophytodienoate reductase 31.3.1.420.441
3isjA8DPantothenate synthetase6.3.2.10.441
3ivgFG5Pantothenate synthetase6.3.2.10.441
3l0lHC3Nuclear receptor ROR-gamma/0.441
3mcyZH1FimH/0.441
3nguADPNucleoside diphosphate kinase/0.441
3ox4NADAlcohol dehydrogenase 21.1.1.10.441
3u5sFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.441
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.441
3vrwYS5Vitamin D3 receptor/0.441
3vsoEK1Peroxisome proliferator-activated receptor gamma/0.441
3vvpBNUUncharacterized protein/0.441
4a95NHWGlycylpeptide N-tetradecanoyltransferase/0.441
4dan2FAPurine nucleoside phosphorylase DeoD-type2.4.2.10.441
4hlg20BTankyrase-22.4.2.300.441
4i02CMPcAMP-activated global transcriptional regulator CRP/0.441
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.441
4lsjLSJGlucocorticoid receptor/0.441
4n1fCZHObelin/0.441
4n9qFMNFMN-dependent NADH-azoreductase 1/0.441
4tlbAGSCircadian clock protein kinase KaiC2.7.11.10.441
4ubvCOASteroid 3-ketoacyl-CoA thiolase/0.441
5bt42LOBromodomain-containing protein 4/0.441
5kwvANPPantothenate synthetase/0.441
6stdMS2Scytalone dehydratase4.2.1.940.441
1ahiCHO7-alpha-hydroxysteroid dehydrogenase1.1.1.1590.440
1dg7WRBDihydrofolate reductase1.5.1.30.440
1e1nFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.440
1f5fDHTSex hormone-binding globulin/0.440
1h73ANPHomoserine kinase2.7.1.390.440
1hfrMOTDihydrofolate reductase1.5.1.30.440
1i7iAZ2Peroxisome proliferator-activated receptor gamma/0.440
1jjeBYSBeta-lactamase/0.440
1kquBR4Phospholipase A2, membrane associated/0.440
1m13HYFNuclear receptor subfamily 1 group I member 2/0.440
1m8jNADNicotinamide-nucleotide adenylyltransferase2.7.7.10.440
1o1vTCHGastrotropin/0.440
1o6qR17Squalene--hopene cyclase4.2.1.1290.440
1ohkCOPDihydrofolate reductase1.5.1.30.440
1qiqACCIsopenicillin N synthase1.21.3.10.440
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.440
1rj6AZMCarbonic anhydrase 144.2.1.10.440
1s19MC9Vitamin D3 receptor/0.440
1svmATPLarge T antigen3.6.40.440
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
1ychFMNNitric oxide reductase10.440
2an9GDPGuanylate kinase2.7.4.80.440
2eldSAHDiphthine synthase/0.440
2fonFADAcyl-coenzyme A oxidase/0.440
2g78REACellular retinoic acid-binding protein 2/0.440
2gesCOKPantothenate kinase2.7.1.330.440
2hvdADPNucleoside diphosphate kinase A2.7.4.60.440
2npaMMBPeroxisome proliferator-activated receptor alpha/0.440
2p1t3TNRetinoic acid receptor RXR-alpha/0.440
2pb4SAHDiphthine synthase/0.440
2r5nTPPTransketolase 1/0.440
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.440
2wetFADTryptophan 5-halogenase/0.440
2wqoVGKSerine/threonine-protein kinase Nek22.7.11.10.440
2z4jDHTAndrogen receptor/0.440
3chr4BSLeukotriene A-4 hydrolase3.3.2.60.440
3ckqUPGGlucosyl-3-phosphoglycerate synthase2.4.1.2660.440
3d0bSNXHeat shock protein HSP 90-alpha/0.440
3fraI2HDihydrofolate reductase1.5.1.30.440
3is9AC7Gag-Pol polyprotein2.7.7.490.440
3lfeZ84Mitogen-activated protein kinase 14/0.440
3ntz3TZDihydrofolate reductase1.5.1.30.440
3o3pGDDGlycosyl transferase, family 2/0.440
3qlwN22Dihydrofolate reductase1.5.1.30.440
3r6tLU1Catechol O-methyltransferase2.1.1.60.440
3rucNADUDP-N-acetylglucosamine 4-epimerase/0.440
3sxjSAMPutative methyltransferase/0.440
3vt45YIVitamin D3 receptor/0.440
3zeiAWHO-acetylserine sulfhydrylase/0.440
4a2zMYAGlycylpeptide N-tetradecanoyltransferase/0.440
4awmKDHPolymerase acidic protein/0.440
4bfzZVZPantothenate kinase2.7.1.330.440
4hkiFLNTankyrase-22.4.2.300.440
4if5ACOAlpha-tubulin N-acetyltransferase 1/0.440
4ixd1HVIntegrin alpha-L/0.440
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.440
4l091URTankyrase-22.4.2.300.440
4lb2DM5Serum albumin/0.440
4ma628EAra h 8 allergen/0.440
4qtuSAM18S rRNA (guanine(1575)-N(7))-methyltransferase/0.440
4rr9A3SProbable threonine--tRNA ligase 26.1.1.30.440
4yaw2AMNADPH--cytochrome P450 reductase/0.440
4yerADPAntibiotic ABC transporter, ATP-binding protein, putative/0.440
5a2yUTPMitochondrial poly(A) polymerase/0.440
5stdUNNScytalone dehydratase4.2.1.940.440