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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2dxeGDPNucleoside diphosphate kinase2.7.4.6

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
2dxeGDPNucleoside diphosphate kinase2.7.4.61.000
2dy9ADPNucleoside diphosphate kinase2.7.4.60.627
2dxfGNPNucleoside diphosphate kinase2.7.4.60.592
4uofDATNucleoside diphosphate kinase/0.571
2dxdANPNucleoside diphosphate kinase2.7.4.60.566
3q8uADPNucleoside diphosphate kinase/0.552
1wklATPNucleoside diphosphate kinase/0.549
3bbfGDPNucleoside diphosphate kinase B2.7.4.60.538
4uohADPNucleoside diphosphate kinase/0.531
1nhkCMPNucleoside diphosphate kinase2.7.4.60.522
1nueGDPNucleoside diphosphate kinase B2.7.4.60.522
2hveADPNucleoside diphosphate kinase A2.7.4.60.520
2nnqT4BFatty acid-binding protein, adipocyte/0.520
3elbC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.516
1lwxAZDNucleoside diphosphate kinase, cytosolic2.7.4.60.514
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.514
3pce3HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.514
3pce3HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.514
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.513
1ndcTYDNucleoside diphosphate kinase, cytosolic2.7.4.60.512
4cmfPXGUncharacterized protein/0.505
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.505
1p8dCO1Oxysterols receptor LXR-beta/0.503
1u1gBBBUridine phosphorylase2.4.2.30.503
3lfzADPUncharacterized protein MJ1225/0.503
3hk1B64Fatty acid-binding protein, adipocyte/0.500
4cdmFO1Deoxyribodipyrimidine photolyase/0.500
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.499
3hmvHBTcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.499
4dpy2P0Mevalonate diphosphate decarboxylase/0.499
1fwmCB3Thymidylate synthase/0.498
2od7A1RNAD-dependent protein deacetylase HST23.5.10.498
4fkxCDPNucleoside diphosphate kinase/0.498
4awtFMNNADH:flavin oxidoreductase Sye1/0.497
5h8tRTLRetinol-binding protein 1/0.497
2o8h227cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.496
1sze173Cytochrome b2, mitochondrial1.1.2.30.495
2f3mGTDGlutathione S-transferase Mu 12.5.1.180.495
2oegUPGUDP-glucose pyrophosphorylase/0.495
3kai4FIPeptidyl-prolyl cis-trans isomerase NIMA-interacting 15.2.1.80.494
1mdtAPUDiphtheria toxin/0.492
3up0D7SaceDAF-12/0.492
4hfr14MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.491
1pq944BOxysterols receptor LXR-beta/0.490
1towCRZFatty acid-binding protein, adipocyte/0.490
1z6tADPApoptotic protease-activating factor 1/0.490
2bf7HBIPteridine reductase 11.5.1.330.489
2gjlFMNNitronate monooxygenase1.13.12.160.489
2xvw9NRSerum albumin/0.489
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.489
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.489
4m2bUPGUDP-glucose pyrophosphorylase/0.489
4oew5IOcGMP-specific 3',5'-cyclic phosphodiesterase/0.488
1iayAVG1-aminocyclopropane-1-carboxylate synthase 24.4.1.140.487
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.487
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.487
2xdaJPS3-dehydroquinate dehydratase4.2.1.100.487
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.487
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.487
1kt8ILPBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.486
1touB1VFatty acid-binding protein, adipocyte/0.486
2aj8SC3Dipeptidyl peptidase 4/0.486
2e0nSAHPrecorrin-2 C20-methyltransferase/0.486
2yp0OVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.486
4y9lFADAcyl-CoA dehydrogenase family member 11/0.486
2ix5FADAcyl-coenzyme A oxidase 4, peroxisomal1.3.3.60.485
3qpoPFRcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.485
4fqsLYAThymidylate synthase ThyA/0.485
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.484
2idkC2FGlycine N-methyltransferase2.1.1.200.484
4bfyZVYPantothenate kinase2.7.1.330.484
4kc1WS1Histo-blood group ABO system transferase/0.484
5agyGTBTau class glutathione S-transferase/0.484
5iqgGDPBifunctional AAC/APH2.3.10.484
1i59ANPChemotaxis protein CheA2.7.13.30.483
2v2zADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.483
3juoAJDPhenazine biosynthesis protein A/B/0.483
4b66NAPL-ornithine N(5)-monooxygenase/0.483
4iaq2GM5-hydroxytryptamine receptor 1B/0.483
4u0sADPAdenosine monophosphate-protein transferase FICD2.7.7.n10.483
4yekTHMThymidine phosphorylase/0.483
2vd0D27Hematopoietic prostaglandin D synthase/0.482
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.482
3fr5I4AFatty acid-binding protein, adipocyte/0.482
3hnzPMN3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.482
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.482
1cw3NADAldehyde dehydrogenase, mitochondrial1.2.1.30.481
3pd2A3SThreonine--tRNA ligase6.1.1.30.481
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.481
4kc4WS3Histo-blood group ABO system transferase/0.481
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.480
1yciNDFHypoxia-inducible factor 1-alpha inhibitor1.14.11.300.480
1zdwFLVPrenyltransferase/0.480
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.480
2zshGA3Gibberellin receptor GID1A30.480
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.480
5cpmFNRNADH:flavin oxidoreductase/0.480
5iqbGNPBifunctional AAC/APH2.3.10.480
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.479
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.479
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.479
3bgxTMPThymidylate synthase/0.479
1wxjIPLTryptophan synthase alpha chain/0.478
4jva1ORcAMP-dependent protein kinase type II-beta regulatory subunit/0.478
4l1xSTRAldo-keto reductase family 1 member C2/0.478
4qzuRTLRetinol-binding protein 2/0.478
4rrrA3TThreonine--tRNA ligase6.1.1.30.478
1a4zNADAldehyde dehydrogenase, mitochondrial1.2.1.30.477
1n3sGTPGTP cyclohydrolase 13.5.4.160.477
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.477
2ydbNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.477
3eksCY9Actin-5C/0.477
3p0fBAUUridine phosphorylase 22.4.2.30.477
3sfh1DIHistone deacetylase 83.5.1.980.477
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.477
4tlaADPCircadian clock protein kinase KaiC2.7.11.10.477
5gcnCOAHAT A1/0.477
1dhfFOLDihydrofolate reductase1.5.1.30.476
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.476
1pqc444Oxysterols receptor LXR-beta/0.476
1t7o152Carnitine O-acetyltransferase2.3.1.70.476
1zknIBMcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.476
2b56UTPRNA editing complex protein MP57/0.476
2isjFMN5,6-dimethylbenzimidazole synthase1.13.11.790.476
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.476
4b6r3DQ3-dehydroquinate dehydratase4.2.1.100.476
4g2yNI5cGMP-specific 3',5'-cyclic phosphodiesterase/0.476
4g8cC6LAlpha/beta hydrolase fold protein/0.476
4h1e10JBeta-secretase 13.4.23.460.476
1mrqSTRAldo-keto reductase family 1 member C1/0.475
2fm0M98cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.475
2xb8XNW3-dehydroquinate dehydratase4.2.1.100.475
2yphQQY2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.475
3v2uATPProtein GAL3/0.475
4g2wNI0cGMP-specific 3',5'-cyclic phosphodiesterase/0.475
4ho4THMGlucose-1-phosphate thymidylyltransferase/0.475
1o04NADAldehyde dehydrogenase, mitochondrial1.2.1.30.474
1q9mROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.474
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.474
2yeiXQIHeat shock protein HSP 90-alpha/0.474
2yozOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.474
3d9zD9ZCarbonic anhydrase 24.2.1.10.474
3dazMZMCarbonic anhydrase 24.2.1.10.474
3eblGA4Gibberellin receptor GID1/0.474
3i0aDBHNeutrophil gelatinase-associated lipocalin/0.474
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.474
3pchCHBProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.474
3zbrNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.474
4dlcUMPDeoxyuridine triphosphatase, putative/0.474
1xoqROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.473
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.473
2fbwCBESuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial1.3.5.10.473
2fbwCBESuccinate dehydrogenase cytochrome b, large subunit/0.473
3t4hMD5Alpha-ketoglutarate-dependent dioxygenase AlkB1.14.11.330.473
4bb2STRCorticosteroid-binding globulin/0.473
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.473
4iarERM5-hydroxytryptamine receptor 1B/0.473
4mv4ACPBiotin carboxylase6.3.4.140.473
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.473
4xw5ATPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.473
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.472
1ro98BRcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.472
1v93FADMethylenetetrahydrofolate reductase/0.472
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.472
3n0nP9BCarbonic anhydrase 24.2.1.10.472
3w6uNAP6-phosphogluconate dehydrogenase, NAD-binding protein/0.472
3zoiM2WIsopenicillin N synthase1.21.3.10.472
4b1d6TGBeta-secretase 13.4.23.460.472
4ytnFD8Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial/0.472
4ytnFD8Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial/0.472
4ytnFD8Succinate dehydrogenase cytochrome b560/0.472
1ngsTPPTransketolase 12.2.1.10.471
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.471
1rx1NAPDihydrofolate reductase1.5.1.30.471
1t8xPEP2-dehydro-3-deoxyphosphooctonate aldolase2.5.1.550.471
2aclL05Oxysterols receptor LXR-alpha/0.471
2az3CDPNucleoside diphosphate kinase/0.471
2cftPLPPyridoxal phosphate phosphatase/0.471
2iviACWIsopenicillin N synthase1.21.3.10.471
2w3bNDPDihydrofolate reductase1.5.1.30.471
2wzwFMNNitroreductase NfnB/0.471
2zsiGA4Gibberellin receptor GID1A30.471
4dptAGSMevalonate diphosphate decarboxylase/0.471
4njoNADD-3-phosphoglycerate dehydrogenase, putative/0.471
4prxADPDNA gyrase subunit B/0.471
4uy6SAHHistidine N-alpha-methyltransferase/0.471
1dr4HBIDihydrofolate reductase1.5.1.30.470
1psdNADD-3-phosphoglycerate dehydrogenase1.1.1.950.470
1reqDCAMethylmalonyl-CoA mutase large subunit5.4.99.20.470
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.470
1ykdCMPAdenylate cyclase/0.470
3ddw055Glycogen phosphorylase, liver form2.4.1.10.470
3fgoACPSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.470
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.470
4jzr4JREgl nine homolog 1/0.470
5dp2NAPCurF/0.470
1bn1AL5Carbonic anhydrase 24.2.1.10.469
1dghNDPCatalase1.11.1.60.469
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.469
1sa4JANProtein farnesyltransferase subunit beta2.5.1.580.469
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.469
2an9GDPGuanylate kinase2.7.4.80.469
2c4jGSOGlutathione S-transferase Mu 22.5.1.180.469
2hl2SSAThreonine--tRNA ligase6.1.1.30.469
2yoj8Y6Genome polyprotein2.7.7.480.469
3wv7ADPHmd co-occurring protein HcgE/0.469
4dk70KSOxysterols receptor LXR-beta/0.469
4fcd0T6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.469
4lzwTHMUridine phosphorylase/0.469
4rrgA3TThreonine--tRNA ligase6.1.1.30.469
5hgcHCYUncharacterized protein/0.469
1h8hADPATP synthase subunit alpha, mitochondrial/0.468
1h8hADPATP synthase subunit beta, mitochondrial3.6.3.140.468
1jqiFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial/0.468
1lnmDTXBilin-binding protein/0.468
1o5iNAD3-oxoacyl-(Acyl carrier protein) reductase/0.468
1ttm667Carbonic anhydrase 24.2.1.10.468
1u1f183Uridine phosphorylase2.4.2.30.468
1yobFMNFlavodoxin 2/0.468
2eiiNAD1-pyrroline-5-carboxylate dehydrogenase/0.468
3fazNOSPurine nucleoside phosphorylase/0.468
3n76CA23-dehydroquinate dehydratase4.2.1.100.468
3tfuPL8Adenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.468
3up5NAP2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.468
3v0o4GWHisto-blood group ABO system transferase/0.468
3zbsOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.468
4c72TLG3-oxoacyl-ACP synthase/0.468
4cf7ADPAdenylate kinase/0.468
4eilUMPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.468
4rrkA3TProbable threonine--tRNA ligase 26.1.1.30.468
5dw60T1Succinyl-CoA:acetate CoA-transferase/0.468
5iqeGNPBifunctional AAC/APH2.3.10.468
5iqiGNPBifunctional AAC/APH2.3.10.468
1a9cGTPGTP cyclohydrolase 13.5.4.160.467
1eqbFFOSerine hydroxymethyltransferase2.1.2.10.467
1p4mADPRiboflavin kinase2.7.1.260.467
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.467
2j9lATPH(+)/Cl(-) exchange transporter 5/0.467
2rlcCHDCholoylglycine hydrolase3.5.1.240.467
3aivHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic3.2.1.1820.467
3cr0809Wee1-like protein kinase2.7.10.20.467
4acuQN7Beta-secretase 13.4.23.460.467
4rr6A3SProbable threonine--tRNA ligase 26.1.1.30.467
1bnnAL1Carbonic anhydrase 24.2.1.10.466
1o6qR17Squalene--hopene cyclase4.2.1.1290.466
1oc1ASVIsopenicillin N synthase1.21.3.10.466
2jb4A14Isopenicillin N synthase1.21.3.10.466
2xb9XNW3-dehydroquinate dehydratase4.2.1.100.466
3dcsMZMCarbonic anhydrase 24.2.1.10.466
3djfBC3Purine nucleoside phosphorylase/0.466
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.466
4psbGA3Cytokinin-specific binding protein/0.466
4wfr2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.466
5a3cNADSIR2 family protein/0.466
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.465
1upw444Oxysterols receptor LXR-beta/0.465
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.465
2vteIK4UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.465
3b9lAZZSerum albumin/0.465
3dcwEZLCarbonic anhydrase 24.2.1.10.465
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.465
3k8q22APurine nucleoside phosphorylase2.4.2.10.465
3k8yGNPGTPase HRas/0.465
4dc0NDPPutative ketoacyl reductase1.3.10.465
5c80URIUridine phosphorylase/0.465
1k9sFM2Purine nucleoside phosphorylase DeoD-type/0.464
1nenDNTSuccinate dehydrogenase iron-sulfur subunit1.3.5.10.464
1nenDNTSuccinate dehydrogenase cytochrome b556 subunit/0.464
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.464
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.464
2cjfRP43-dehydroquinate dehydratase4.2.1.100.464
3c35KAIGlutamate receptor ionotropic, kainate 1/0.464
3ed1GA3Gibberellin receptor GID1/0.464
3fhxPLPPyridoxal kinase2.7.1.350.464
3pcnDHYProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.464
3pcnDHYProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.464
3v0m5GWHisto-blood group ABO system transferase/0.464
4b63NAPL-ornithine N(5)-monooxygenase/0.464
1gky5GPGuanylate kinase2.7.4.80.463
1hb1OCVIsopenicillin N synthase1.21.3.10.463
1itzTPPTransketolase, chloroplastic2.2.1.10.463
1kmyBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.463
2dvlFADAcyl-CoA dehydrogenase/0.463
2fr1NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.463
2p4sDIHAGAP005945-PA/0.463
2qo7ANPEphrin type-A receptor 32.7.10.10.463
2ydd2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.463
3k2fNKXCarbonic anhydrase 24.2.1.10.463
3nbrASDSteroid Delta-isomerase5.3.3.10.463
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.463
3p8iFMNPentaerythritol tetranitrate reductase/0.463
4fcb0T7cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.463
5iqaGNPBifunctional AAC/APH2.3.10.463
1buxPPSNucleoside diphosphate kinase, cytosolic2.7.4.60.462
1dr3HBIDihydrofolate reductase1.5.1.30.462
1i24UPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.462
1nzdUPGDNA beta-glucosyltransferase/0.462
1s19MC9Vitamin D3 receptor/0.462
1tkaN3TTransketolase 12.2.1.10.462
2bjsACVIsopenicillin N synthase1.21.3.10.462
2qzsADPGlycogen synthase2.4.1.210.462
2v1aFMNNPH1-1/0.462
2yxuATPPyridoxal kinase2.7.1.350.462
3biz61EWee1-like protein kinase2.7.10.20.462
3dhbC6LN-acyl homoserine lactonase AiiA3.1.1.810.462
3fpkFADFerredoxin-NADP reductase/0.462
3n4bWWZCarbonic anhydrase 24.2.1.10.462
3oimVZ5Carbonic anhydrase 24.2.1.10.462
3oy0OY0Carbonic anhydrase 24.2.1.10.462
3tvxPNXcAMP-specific 3',5'-cyclic phosphodiesterase 4A3.1.4.530.462
3vi7CBDHematopoietic prostaglandin D synthase/0.462
4a83DXCMajor pollen allergen Bet v 1-A/0.462
4df2FMNNADPH dehydrogenase/0.462
4g95OAGDihydrofolate reductase1.5.1.30.462
4gz612VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.462
4rrhA3SProbable threonine--tRNA ligase 26.1.1.30.462
4rupH97Vitamin D3 receptor A/0.462
4tyqAP5Adenylate kinase/0.462
5cc9DDFDihydrofolate reductase1.5.1.30.462
1o6rR19Squalene--hopene cyclase4.2.1.1290.461
1udtVIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.461
1ve3SAMUncharacterized protein/0.461
1zxnADPDNA topoisomerase 2-alpha5.99.1.30.461
2izhBTNStreptavidin/0.461
2xfsJ01Uncharacterized protein/0.461
2xtnGTPGTPase IMAP family member 2/0.461
3csoXNIGenome polyprotein2.7.7.480.461
3djlFADPutative acyl-CoA dehydrogenase AidB1.3.990.461
3o7lANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
3pd4A3GThreonine--tRNA ligase6.1.1.30.461
3sbhE65Carbonic anhydrase 24.2.1.10.461
3sqwANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.461
4fhd0TTSpore photoproduct lyase/0.461
4n5nNAPAcetoacetyl-CoA reductase1.1.1.360.461
4ttaFMCPurine nucleoside phosphorylase DeoD-type/0.461
5c3aURMHisto-blood group ABO system transferase/0.461
5fm6ADPRuvB-like helicase/0.461
5iqhGNPBifunctional AAC/APH2.3.10.461
1be4PCGNucleoside diphosphate kinase A 22.7.4.60.460
1kt7RTLRetinol-binding protein 4/0.460
1kzjCB3Thymidylate synthase/0.460
2a9y26AAdenosine kinase2.7.1.200.460
2bfaCB3Pteridine reductase 11.5.1.330.460
2h4nAZMCarbonic anhydrase 24.2.1.10.460
2iypNAP6-phosphogluconate dehydrogenase, decarboxylating1.1.1.440.460
2wdqCBESuccinate dehydrogenase iron-sulfur subunit1.3.5.10.460
2wdqCBESuccinate dehydrogenase cytochrome b556 subunit/0.460
2y60M8FIsopenicillin N synthase1.21.3.10.460
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.460
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.460
4bfzZVZPantothenate kinase2.7.1.330.460
4hr2ADPNucleoside diphosphate kinase/0.460
4o2rGDPGTP-binding protein Rheb/0.460
4rrlA3SProbable threonine--tRNA ligase 26.1.1.30.460
4u7wNDPMxaA/0.460
5cuqNSCGenome polyprotein/0.460
1ie8KH1Vitamin D3 receptor/0.459
1kt6RTLRetinol-binding protein 4/0.459
1lvu9PPPurine nucleoside phosphorylase2.4.2.10.459
1qd1FONFormimidoyltransferase-cyclodeaminase2.1.2.50.459
1qk35GPHypoxanthine-guanine-xanthine phosphoribosyltransferase2.4.2.220.459
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.459
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.459
1txtCAAHMG-CoA synthase/0.459
1xp8AGSProtein RecA/0.459
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
2f3rG5PGuanylate kinase2.7.4.80.459
2gfxPMN3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.459
2izfBTNStreptavidin/0.459
2wejFB2Carbonic anhydrase 24.2.1.10.459
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
3ekuCY9Actin-5C/0.459
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.459
3q7fED2Uncharacterized protein/0.459
3w0gW07Vitamin D3 receptor/0.459
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
4ho9UTPGlucose-1-phosphate thymidylyltransferase/0.459
4rr8A3SProbable threonine--tRNA ligase 26.1.1.30.459
4wxg2BOSerine hydroxymethyltransferase/0.459
1hb3SCVIsopenicillin N synthase1.21.3.10.458
1nqw5YL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.458
1rfuADPPyridoxal kinase2.7.1.350.458
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.458
1y7lASN_LEU_ASN_ILECysteine synthase2.5.1.470.458
1z7yAA5Cysteine synthase 12.5.1.470.458
1zoyUQ1Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial1.3.5.10.458
1zoyUQ1Succinate dehydrogenase cytochrome b560 subunit, mitochondrial/0.458
2ejzSAHDiphthine synthase/0.458
3pn1IVHDNA ligase/0.458
4b5oACOAlpha-tubulin N-acetyltransferase 1/0.458
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
4ffrATPUncharacterized protein/0.458
4imfSI3N-acetylneuraminate lyase/0.458
4u07ATPAdenosine monophosphate-protein transferase FICD2.7.7.n10.458
5fm7ADPRuvB-like helicase/0.458
8catNDPCatalase1.11.1.60.458
1bzmMZMCarbonic anhydrase 14.2.1.10.457
1pke2FDPurine nucleoside phosphorylase DeoD-type/0.457
1rx5DDFDihydrofolate reductase1.5.1.30.457
1rx8FOLDihydrofolate reductase1.5.1.30.457
1tduCB3Thymidylate synthase/0.457
2b58COADiamine acetyltransferase 1/0.457
2c7qSAHModification methylase HhaI2.1.1.370.457
2dzbHH2Dihydropteroate synthase/0.457
2fznFADBifunctional protein PutA1.5.5.20.457
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.457
2ovyPFJcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.457
2w9hTOPDihydrofolate reductase1.5.1.30.457
2xpc051UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.457
2xvv9DNSerum albumin/0.457
3aosJH2Hemolymph juvenile hormone binding protein/0.457
4fdnFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.457
4iafADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
4ilx1EZCarbonic anhydrase 24.2.1.10.457
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.457
4rrqA3SThreonine--tRNA ligase6.1.1.30.457
5ig2NADShort-chain dehydrogenase/reductase SDR/0.457
1cbsREACellular retinoic acid-binding protein 2/0.456
1nzfUPGDNA beta-glucosyltransferase/0.456
1p0pBCHCholinesterase3.1.1.80.456
1rd4L08Integrin alpha-L/0.456
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.456
2qo9ANPEphrin type-A receptor 32.7.10.10.456
2v2zCDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.456
2wo7ASVIsopenicillin N synthase1.21.3.10.456
2xviFADPutative flavin-containing monooxygenase/0.456
2ykeYKEHeat shock protein HSP 90-alpha/0.456
3b04OOPIsopentenyl-diphosphate delta-isomerase/0.456
3bjcWANcGMP-specific 3',5'-cyclic phosphodiesterase/0.456
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.456
3qge26FGenome polyprotein2.7.7.480.456
3zbzOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.456
4avlTMPPolymerase acidic protein/0.456
4cukNAID-lactate dehydrogenase/0.456
4ia7BIVVitamin D3 receptor A/0.456
4lm4JPZcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.456
4xrbNDPPossible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc/0.456
1gj5130Prothrombin3.4.21.50.455
1if7SBRCarbonic anhydrase 24.2.1.10.455
1szcCNANAD-dependent protein deacetylase HST23.5.10.455
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.455
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.455
2pgtGPRGlutathione S-transferase P2.5.1.180.455
3c8bARG_ARG_GLY_ILE_NH2Botulinum neurotoxin type A3.4.24.690.455
3exnACOProbable acetyltransferase/0.455
3lq2TDPPyruvate dehydrogenase E1 component1.2.4.10.455
3tr05GPGuanylate kinase/0.455
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.455
4c77N01Phenylacetone monooxygenase1.14.13.920.455
4dieC5PCytidylate kinase/0.455
4kc2WS2Histo-blood group ABO system transferase/0.455
4kw51W6Decaprenylphosphoryl-beta-D-ribose oxidase/0.455
4uogYYYNucleoside diphosphate kinase/0.455
4x5iFOLDihydrofolate reductase1.5.1.30.455
1b8oIMHPurine nucleoside phosphorylase2.4.2.10.454
1dljUGAUDP-glucose 6-dehydrogenase/0.454
1dr3TAPDihydrofolate reductase1.5.1.30.454
1q13TESProstaglandin-E(2) 9-reductase1.1.1.1890.454
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.454
1u1cBAUUridine phosphorylase2.4.2.30.454
1u71MXADihydrofolate reductase1.5.1.30.454
1x8b824Wee1-like protein kinase2.7.10.20.454
2bxqIMNSerum albumin/0.454
2fk8SAMHydroxymycolate synthase MmaA42.1.10.454
2hfuMEVMevalonate kinase/0.454
2xupTZ5Acetylcholinesterase3.1.1.70.454
3juqAJDPhenazine biosynthesis protein A/B/0.454
3juqAKDPhenazine biosynthesis protein A/B/0.454
3kigDA4Carbonic anhydrase 24.2.1.10.454
3nguADPNucleoside diphosphate kinase/0.454
3nmpPYVAbscisic acid receptor PYL2/0.454
3nx2FERFerulic acid decarboxylase/0.454
3qpnPFKcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.454
3uhmRFNUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.454
3vv8B02Beta-secretase 13.4.23.460.454
4bewACPSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.454
4h0vNADIota toxin component Ia/0.454
4jauADPSensor histidine kinase/0.454
4muw2F4cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.454
4pt3NDPAldehyde dehydrogenase/0.454
5c4fUPGHisto-blood group ABO system transferase/0.454
1luqBTNStreptavidin/0.453
1oynROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.453
1pd9CO4Dihydrofolate reductase1.5.1.30.453
1q4l679Glycogen synthase kinase-3 beta2.7.11.260.453
1thnADPAnti-sigma F factor/0.453
1wwkNAD307aa long hypothetical phosphoglycerate dehydrogenase/0.453
2g0lFLNNeocarzinostatin/0.453
2nx3PEP2-dehydro-3-deoxyphosphooctonate aldolase2.5.1.550.453
2poqISDTrans-1,2-dihydrobenzene-1,2-diol dehydrogenase1.3.1.200.453
2x0eTYDWsaF/0.453
3betCTFCarbonic anhydrase 24.2.1.10.453
3dd0EZLCarbonic anhydrase 24.2.1.10.453
3eheNADUDP-glucose 4-epimerase (GalE-1)/0.453
3f0aACOSpermidine N(1)-acetyltransferase/0.453
3fr4F8AFatty acid-binding protein, adipocyte/0.453
3g0cRUFDipeptidyl peptidase 4/0.453
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.453
3nwlNDPCatalase1.11.1.60.453
4b4w9L9Bifunctional protein FolD/0.453
4bb5HD2Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.453
4bf19FKCarbonic anhydrase 24.2.1.10.453
4d965PAD-cysteine desulfhydrase/0.453
4gdaBTNStreptavidin/0.453
4h4o506Gag-Pol polyprotein2.7.7.490.453
4ixd1HVIntegrin alpha-L/0.453
4j7xNAPSepiapterin reductase1.1.1.1530.453
4n82FMNRibonucleotide reductase (NrdI family protein), putative/0.453
4nceMGTPolymerase basic protein 2/0.453
4wdfA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.453
4wxfPLGSerine hydroxymethyltransferase/0.453
5dn1AMZPhosphoribosyl isomerase A5.3.1.160.453
1fw0KAIGlutamate receptor 2/0.452
1rfvADPPyridoxal kinase2.7.1.350.452
1tllNAPNitric oxide synthase, brain1.14.13.390.452
1w19T2P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.452
1xagNAD3-dehydroquinate synthase/0.452
2gouFMNNADH:flavin oxidoreductase Sye1/0.452
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.452
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.452
2qbr910Tyrosine-protein phosphatase non-receptor type 13.1.3.480.452
2wyaHMGHydroxymethylglutaryl-CoA synthase, mitochondrial2.3.3.100.452
3g4kROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.452
3vruYS3Vitamin D3 receptor/0.452
3vrvYSDVitamin D3 receptor/0.452
4dz7D02Carbonic anhydrase 24.2.1.10.452
4gts7TPGeranylgeranyl transferase type-2 subunit beta2.5.1.600.452
4xz3COAAcyl-CoA synthetase (NDP forming)/0.452
5e5h0T1Succinyl-CoA:acetate CoA-transferase/0.452
1foaUD1Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase2.4.1.1010.451
1gpeFADGlucose oxidase1.1.3.40.451
1h50FMNPentaerythritol tetranitrate reductase/0.451
1mjaCOAHistone acetyltransferase ESA1/0.451
1n0uSO1Elongation factor 2/0.451
1nd52BFProstatic acid phosphatase3.1.3.20.451
1s3uTQDDihydrofolate reductase1.5.1.30.451
2bxmIMNSerum albumin/0.451
2g1r3IGRenin3.4.23.150.451
2o4jVD4Vitamin D3 receptor/0.451
2x7uWZACarbonic anhydrase 24.2.1.10.451
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.451
3akn11DFatty acid-binding protein, intestinal/0.451
3dbuD8WCarbonic anhydrase 24.2.1.10.451
3fun798Leukotriene A-4 hydrolase3.3.2.60.451
4b67NAPL-ornithine N(5)-monooxygenase/0.451
4eb5PLPCysteine desulfurase IscS 2/0.451
4friDWABeta-secretase 13.4.23.460.451
4gyzD5MTyrosyl-DNA phosphodiesterase 23.1.40.451
4jazSTLPeroxisome proliferator-activated receptor gamma/0.451
4kap1QVCarbonic anhydrase 24.2.1.10.451
4ure1PSCyclohexanol dehydrogenase/0.451
5cfn2BAStimulator of interferon genes protein/0.451
1blzACVIsopenicillin N synthase1.21.3.10.450
1dggNDPCatalase1.11.1.60.450
1hfqMOTDihydrofolate reductase1.5.1.30.450
1kt3RTLRetinol-binding protein 4/0.450
1ro6ROLcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.450
1rp4FADEndoplasmic oxidoreductin-11.8.40.450
1rx4DDFDihydrofolate reductase1.5.1.30.450
1v48HA1Purine nucleoside phosphorylase2.4.2.10.450
1x1cSAHC-20 methyltransferase/0.450
2a2cADPN-acetylgalactosamine kinase2.7.1.1570.450
2abjCBCBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.450
2bfmTOPPteridine reductase 11.5.1.330.450
2c20NADUDP-glucose 4-epimerase/0.450
2f2uM77Rho-associated protein kinase 22.7.11.10.450
2fb35ADGTP 3',8-cyclase4.1.99.180.450
2ftoCB3Thymidylate synthase/0.450
2fzbTOLAldose reductase1.1.1.210.450
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.450
2ylrNAPPhenylacetone monooxygenase1.14.13.920.450
3dccD9ZCarbonic anhydrase 24.2.1.10.450
3fhiANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
3gi2GHWDihydrofolate reductase1.5.1.30.450
3m2vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.450
3t3iGPWGlycogen phosphorylase, muscle form2.4.1.10.450
4e2wJHZMethyltransferase/0.450
4rrmA3TProbable threonine--tRNA ligase 26.1.1.30.450
4ttiFMCPurine nucleoside phosphorylase DeoD-type/0.450
4y17LAETranscriptional regulator of ftsQAZ gene cluster/0.450
5iotUMPFlavin-dependent thymidylate synthase2.1.1.1480.450
1b5eDCMDeoxycytidylate 5-hydroxymethyltransferase2.1.2.80.449
1bntAL2Carbonic anhydrase 24.2.1.10.449
1hquHBYGag-Pol polyprotein2.7.7.490.449
1i2lDCSAminodeoxychorismate lyase4.1.3.380.449
1in5ADPHolliday junction ATP-dependent DNA helicase RuvB/0.449
1jnrFADAdenylylsulfate reductase, subunit A (AprA)/0.449
1kvkATPMevalonate kinase2.7.1.360.449
1ot7CHCBile acid receptor/0.449
1p0ePRFQueuine tRNA-ribosyltransferase2.4.2.290.449
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.449
1r2jFADFkbI/0.449
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.449
1rctNOSPurine nucleoside phosphorylase2.4.2.10.449
1tvrTB9Gag-Pol polyprotein2.7.7.490.449
1y1rANUUridine phosphorylase2.4.2.30.449
2h447CAcGMP-specific 3',5'-cyclic phosphodiesterase/0.449
2j40NAD1-pyrroline-5-carboxylate dehydrogenase/0.449
2r8oT5XTransketolase 1/0.449
2rdn1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.449
2vetUMPThymidylate synthase/0.449
2vhxNADAlanine dehydrogenase1.4.1.10.449
2xvhNAPPutative flavin-containing monooxygenase/0.449
2y6fM9FIsopenicillin N synthase1.21.3.10.449
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
3g5qFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.449
3idcANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
3tdtCOA2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase2.3.1.1170.449
3zpoK0IHistone demethylase UTY1.14.110.449
4ajgF07cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.449
4bv9NDPKetimine reductase mu-crystallin1.5.1.250.449
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.449
4fr8NADAldehyde dehydrogenase, mitochondrial1.2.1.30.449
4h3j10WBeta-secretase 13.4.23.460.449
4rnwFMNNADPH dehydrogenase 11.6.99.10.449
1ddtAPUDiphtheria toxin/0.448
1dfoPLGSerine hydroxymethyltransferase2.1.2.10.448
1wur8DGGTP cyclohydrolase 1/0.448
2bu9HFVIsopenicillin N synthase1.21.3.10.448
2djlFMNDihydroorotate dehydrogenase (fumarate)1.3.98.10.448
2fjdSFDAdenylylsulfate reductase, subunit A (AprA)/0.448
2j5sKTAAlr4455 protein/0.448
2qc8ADPGlutamine synthetase6.3.1.20.448
2wehFB1Carbonic anhydrase 24.2.1.10.448
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
3fbeGDPNucleoside diphosphate kinase2.7.4.60.448
3fktSIIBeta-secretase 13.4.23.460.448
3hxcBD6Geranylgeranyl transferase type-2 subunit beta2.5.1.600.448
3jq3ADPLombricine kinase/0.448
3jszUPGUncharacterized protein/0.448
3lbhGNPGTPase HRas/0.448
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
3ndjJHZMethyltransferase/0.448
3tlc7MDMicrocin C7 self-immunity protein MccF/0.448
3v0p4GWHisto-blood group ABO system transferase/0.448
3zlmANPAdenosine monophosphate-protein transferase NmFic2.7.7.n10.448
4a5lNDPThioredoxin reductase/0.448
4eqrFADCoenzyme A disulfide reductase/0.448
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4g2i0VQVitamin D3 receptor/0.448
4hkfACOAlpha-tubulin N-acetyltransferase 1/0.448
4hu1V13Carbonic anhydrase 134.2.1.10.448
4iteTEYVitamin D3 receptor/0.448
4m6jNDPDihydrofolate reductase1.5.1.30.448
4rriA3TProbable threonine--tRNA ligase 26.1.1.30.448
4xfjANPArgininosuccinate synthase/0.448
4zzjCNANAD-dependent protein deacetylase sirtuin-13.5.10.448
1e1cDCAMethylmalonyl-CoA mutase large subunit5.4.99.20.447
1euyQSIGlutamine--tRNA ligase6.1.1.180.447
1jcm137Tryptophan biosynthesis protein TrpCF4.1.1.480.447
1kwrSG2Carbonic anhydrase 24.2.1.10.447
1vf3GDNGlutathione S-transferase 32.5.1.180.447
2aqbTL63-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.447
2he5NDPAldo-keto reductase family 1 member C211.1.10.447
2oc4IMHPurine nucleoside phosphorylase2.4.2.10.447
2rqfJH3Hemolymph juvenile hormone binding protein/0.447
3bi6396Wee1-like protein kinase2.7.10.20.447
3dmhSAMProbable ribosomal RNA small subunit methyltransferase/0.447
3g1oRF1HTH-type transcriptional regulator EthR/0.447
3mauPLRPutative sphingosine-1-phosphate lyase/0.447
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.447
3nj0PYVAbscisic acid receptor PYL2/0.447
4c3yANB3-ketosteroid dehydrogenase/0.447
4e32DWNMethyltransferase/0.447
4itoMPXCarbonic anhydrase 24.2.1.10.447
4ldjGDPGTPase KRas/0.447
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
4nhyPD2Prolyl 3-hydroxylase OGFOD11.14.110.447
4obuPLPPyridoxal-dependent decarboxylase domain protein/0.447
4qx5CMPcGMP-dependent protein kinase 12.7.11.120.447
4u9yCOAAlpha-tubulin N-acetyltransferase 1/0.447
4yx6FMNOmega-3 polyunsaturated fatty acid synthase subunit PfaD/0.447
5bp9SAHPutative methyltransferase protein/0.447
1d5cGDPGTPase (Rab6)/0.446
1el4CTZObelin/0.446
1i59ADPChemotaxis protein CheA2.7.13.30.446
1jdzFMBPurine nucleoside phosphorylase/0.446
1kw6BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.446
1l0oADPAnti-sigma F factor/0.446
1obnASVIsopenicillin N synthase1.21.3.10.446
1osvCHCBile acid receptor/0.446
1paxDHQPoly [ADP-ribose] polymerase 12.4.2.300.446
1rkpIBMcGMP-specific 3',5'-cyclic phosphodiesterase/0.446
1vyrFMNPentaerythritol tetranitrate reductase/0.446
1xvaSAMGlycine N-methyltransferase2.1.1.200.446
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.446
2d3aADPGlutamine synthetase root isozyme 36.3.1.20.446
2fjeFADAdenylylsulfate reductase, subunit A (AprA)/0.446
2h15B19Carbonic anhydrase 24.2.1.10.446
2jizADPATP synthase subunit beta, mitochondrial3.6.3.140.446
2pbzATPUncharacterized protein/0.446
2prh238Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.446
2qcsANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
2wi72KLHeat shock protein HSP 90-alpha/0.446
3akm11DFatty acid-binding protein, intestinal/0.446
3bl1BL1Carbonic anhydrase 24.2.1.10.446
3d7zGK5Mitogen-activated protein kinase 14/0.446
3dc3AZMCarbonic anhydrase 24.2.1.10.446
3fr28CAFatty acid-binding protein, adipocyte/0.446
3g11P9C3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.446
3gbuATPUncharacterized sugar kinase PH14592.7.10.446
3i8p8403-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.446
3imgBZ2Pantothenate synthetase6.3.2.10.446
3mp3HGGHydroxymethylglutaryl-CoA lyase, mitochondrial4.1.3.40.446
4briUNPEctonucleoside triphosphate diphosphohydrolase I/0.446
4d03NAPPhenylacetone monooxygenase1.14.13.920.446
4da7AC2Purine nucleoside phosphorylase DeoD-type2.4.2.10.446
4g20484Vitamin D3 receptor A/0.446
4igfCHVEnoyl-acyl carrier reductase/0.446
4kniE1ECarbonic anhydrase 24.2.1.10.446
4qbiAP5Adenylate kinase/0.446
4rraA3TProbable threonine--tRNA ligase 26.1.1.30.446
4v0s2HN3-dehydroquinate dehydratase4.2.1.100.446
5kgjACOPredicted acetyltransferase/0.446
4ug2NGIAdenosine receptor A2a/0.446
1dgbNDPCatalase1.11.1.60.445
1gveNAPAflatoxin B1 aldehyde reductase member 310.445
1h36R88Squalene--hopene cyclase4.2.1.1290.445
1h66RH1NAD(P)H dehydrogenase [quinone] 11.6.5.20.445
1i5aACPChemotaxis protein CheA2.7.13.30.445
1lhuESTSex hormone-binding globulin/0.445
1ni12C5Protein farnesyltransferase subunit beta2.5.1.580.445
1p5rCOAFormyl-CoA:oxalate CoA-transferase/0.445
1q6yCOAFormyl-CoA:oxalate CoA-transferase/0.445
1u0hFOKAdenylate cyclase type 2/0.445
1u0hFOKAdenylate cyclase type 5/0.445
2ea2F77Methionine aminopeptidase 2/0.445
2iqgF2IBeta-secretase 13.4.23.460.445
2pmlANPUncharacterized protein/0.445
2vcmM11Isopenicillin N synthase1.21.3.10.445
3c8aARG_ARG_GLY_LEU_NH2Botulinum neurotoxin type A3.4.24.690.445
3dd82C7Carbonic anhydrase 24.2.1.10.445
3e39FMNNitroreductase/0.445
3hivTXNrRNA N-glycosidase/0.445
3qt62P0Mevalonate diphosphate decarboxylase/0.445
3sff0DIHistone deacetylase 83.5.1.980.445
3sl8JN7cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.445
3vrwYS5Vitamin D3 receptor/0.445
3w0hW12Vitamin D3 receptor/0.445
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.445
4bmpFMNProtein NrdI/0.445
4dh5ADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
4du6GTPGTP cyclohydrolase 1/0.445
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.445
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.445
4jhz1KVBeta-glucuronidase3.2.1.310.445
4jin1L7RIO-type serine/threonine-protein kinase Rio12.7.11.10.445
4nhkPD2Prolyl 3,4-dihydroxylase TPA11.14.110.445
4rh10TTSpore photoproduct lyase/0.445
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.445
5cyqT27Gag-Pol polyprotein2.7.7.490.445
5stdUNNScytalone dehydratase4.2.1.940.445
1bn3AL6Carbonic anhydrase 24.2.1.10.444
1ex75GPGuanylate kinase2.7.4.80.444
1g63FMNEpidermin decarboxylase4.1.10.444
1kw8BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.444
1pu9COAHAT A1/0.444
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1x2hLPALipoate-protein ligase A6.3.1.200.444
1zky689Estrogen receptor/0.444
2aiaSB8Peptide deformylase/0.444
2bp1NDPAflatoxin B1 aldehyde reductase member 2/0.444
2c5lGTPGTPase HRas/0.444
2cjeDUNDUTPase/0.444
2gvdFKPAdenylate cyclase type 2/0.444
2gvdFKPAdenylate cyclase type 5/0.444
2hb7O1CVitamin D3 receptor/0.444
2rfiSAHHistone-lysine N-methyltransferase EHMT1/0.444
2vfzUPFN-acetyllactosaminide alpha-1,3-galactosyltransferase/0.444
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.444
3be2RAJVascular endothelial growth factor receptor 22.7.10.10.444
3drcMTXDihydrofolate reductase1.5.1.30.444
3gurBYGGlutathione S-transferase Mu 22.5.1.180.444
3iktNADRedox-sensing transcriptional repressor Rex/0.444
3kmyD8YBeta-secretase 13.4.23.460.444
3ml2SU0Carbonic anhydrase 24.2.1.10.444
3odkODKPeptidyl-prolyl cis-trans isomerase NIMA-interacting 15.2.1.80.444
3of3DIHPurine nucleoside phosphorylase DeoD-type 1/0.444
3pcg4HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.444
3pcg4HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.444
3rs4GNPGTPase HRas/0.444
3w0iO11Vitamin D3 receptor/0.444
3zp4TSAChorismate mutase AroH5.4.99.50.444
4a8v2ANMajor pollen allergen Bet v 1-J/0.444
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.444
4dpi0N1Beta-secretase 13.4.23.460.444
4k7yFMNNADPH dehydrogenase 11.6.99.10.444
4rr7A3SProbable threonine--tRNA ligase 26.1.1.30.444
4tlcAGSCircadian clock protein kinase KaiC2.7.11.10.444
4x5sAZMCarbonic anhydrase (Carbonate dehydratase)/0.444
5c1d12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.444
1cbqRE9Cellular retinoic acid-binding protein 2/0.443
1efaNPFLactose operon repressor/0.443
1lhwESMSex hormone-binding globulin/0.443
1piwNAPNADP-dependent alcohol dehydrogenase 61.1.1.20.443
1qv0CZHObelin/0.443
1swtBTNStreptavidin/0.443
1umaIN2Prothrombin3.4.21.50.443
1vfsDCSAlanine racemase/0.443
1vjtNADAlpha-glucosidase, putative/0.443
1xdpATPPolyphosphate kinase/0.443
1xq04TRCarbonic anhydrase 24.2.1.10.443
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.443
2g1s4IGRenin3.4.23.150.443
2oa7GTXGlutathione S-transferase P 12.5.1.180.443
2w3mFOLDihydrofolate reductase1.5.1.30.443
2y71CB63-dehydroquinate dehydratase4.2.1.100.443
2zvbSAHPrecorrin-3 C17-methyltransferase/0.443
3af1GDPPantothenate kinase2.7.1.330.443
3c89ARG_ARG_GLY_MET_NH2Botulinum neurotoxin type A3.4.24.690.443
3cib314Beta-secretase 13.4.23.460.443
3dyaPZLGag-Pol polyprotein2.7.7.490.443
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3fp0FP015-O-acetyltransferase/0.443
3fpdSAHHistone-lysine N-methyltransferase EHMT1/0.443
3ha5SFGHydroxymycolate synthase MmaA42.1.10.443
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.443
3phjDHKShikimate dehydrogenase (NADP(+))/0.443
3qppPFWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
3sl6JN8cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
3v0n4GWHisto-blood group ABO system transferase/0.443
3zeiAWHO-acetylserine sulfhydrylase/0.443
4a802ANMajor pollen allergen Bet v 1-A/0.443
4dltGNPGTPase HRas/0.443
4gt8ADPSensor protein VraS2.7.13.30.443
4heu15JcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
4kwhNAPReductase homolog/0.443
4nvk2NYPeroxidase/0.443
4z28BTNHoefavidin/0.443
4zqcF6FTryptophan synthase alpha chain/0.443
5esoTDP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.443
5iqdGNPBifunctional AAC/APH2.3.10.443
7catNDPCatalase1.11.1.60.443
1ao8MTXDihydrofolate reductase1.5.1.30.442
1bim0QBRenin3.4.23.150.442
1bn4AL9Carbonic anhydrase 24.2.1.10.442
1fmjRTLRetinol dehydratase/0.442
1gpuTHDTransketolase 12.2.1.10.442
1gtrATPGlutamine--tRNA ligase6.1.1.180.442
1gvrTNLPentaerythritol tetranitrate reductase/0.442
1hrvSDZGenome polyprotein/0.442
1jtqLY3Thymidylate synthase/0.442
1pr0NOSPurine nucleoside phosphorylase DeoD-type/0.442
1qs2NADVip2Ac/0.442
1rkhVD2Vitamin D3 receptor/0.442
1vf2GTXGlutathione S-transferase 32.5.1.180.442
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
2ftoTMPThymidylate synthase/0.442
2wzgUPGUncharacterized protein/0.442
2y67N21UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.442
3o9pMHIPeriplasmic murein peptide-binding protein/0.442
3p84FMNPentaerythritol tetranitrate reductase/0.442
3p97SAMGenome polyprotein2.1.1.560.442
3pd5TSBThreonine--tRNA ligase6.1.1.30.442
3pfdFDAAcyl-CoA dehydrogenase FadE25/0.442
3tifADPUncharacterized ABC transporter ATP-binding protein MJ0796/0.442
4bb3KKAIsopenicillin N synthase1.21.3.10.442
4bfwZVWPantothenate kinase2.7.1.330.442
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
4eu4COASuccinyl-CoA:acetate CoA-transferase/0.442
4gh10WXQueuine tRNA-ribosyltransferase2.4.2.290.442
4jp91M5Beta-secretase 13.4.23.460.442
4ol0GTPGTP-binding nuclear protein Ran/0.442
4qtnNNRNicotinamide riboside transporter PnuC/0.442
4yaf2AMNADPH--cytochrome P450 reductase/0.442
5bnw12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.442
5il1SAMN6-adenosine-methyltransferase 70 kDa subunit/0.442
1cnyEG3Carbonic anhydrase 24.2.1.10.441
1drfFOLDihydrofolate reductase1.5.1.30.441
1ej2NADNicotinamide-nucleotide adenylyltransferase2.7.7.10.441
1h60STRPentaerythritol tetranitrate reductase/0.441
1ie9VDXVitamin D3 receptor/0.441
1kqwRTLCellular retinol-binding protein type II/0.441
1o00NADAldehyde dehydrogenase, mitochondrial1.2.1.30.441
1qtqQSIGlutamine--tRNA ligase6.1.1.180.441
1t31OHHChymase3.4.21.390.441
1t32OHHCathepsin G3.4.21.200.441
1tj0FADBifunctional protein PutA1.5.5.20.441
1uydPU8Heat shock protein HSP 90-alpha/0.441
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.441
2ab8MTPAdenosine kinase2.7.1.200.441
2anb5GPGuanylate kinase2.7.4.80.441
2j9gADPBiotin carboxylase6.3.4.140.441
2pauD5M5'-deoxynucleotidase YfbR/0.441
2rtiGLLStreptavidin/0.441
2vcwZZAHematopoietic prostaglandin D synthase/0.441
2vdgNDPAldose reductase1.1.1.210.441
2wqpWQPPolysialic acid capsule biosynthesis protein SiaC/0.441
2zrvFNRIsopentenyl-diphosphate delta-isomerase/0.441
3c14FOKAdenylate cyclase type 2/0.441
3c14FOKAdenylate cyclase type 5/0.441
3dh7FMNIsopentenyl-diphosphate delta-isomerase/0.441
3dleGFAGag-Pol polyprotein2.7.7.490.441
3eft3BSCarbonic anhydrase 24.2.1.10.441
3ehjACPSensor histidine kinase DesK2.7.13.30.441
3ewkFADSensory box histidine kinase/response regulator/0.441
3gc4AAQQueuine tRNA-ribosyltransferase2.4.2.290.441
3kkoGNPRas-related protein M-Ras/0.441
3oafOAGDihydrofolate reductase1.5.1.30.441
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.441
3sl2ATPSensor histidine kinase WalK/0.441
3uaxNOSPurine nucleoside phosphorylase DeoD-type/0.441
3vf60H6Glucokinase2.7.1.20.441
3vt7VDXVitamin D3 receptor/0.441
3wv9FEGHmd co-occurring protein HcgE/0.441
4b5nFMNNAD(P)H:flavin oxidoreductase Sye4/0.441
4bfuZVUPantothenate kinase2.7.1.330.441
4brdANPEctonucleoside triphosphate diphosphohydrolase I/0.441
4da6GA2Purine nucleoside phosphorylase DeoD-type2.4.2.10.441
4dsnGCPGTPase KRas/0.441
4ht2V50Carbonic anhydrase 124.2.1.10.441
4ia1BIVVitamin D3 receptor A/0.441
4j75TYMTryptophan--tRNA ligase/0.441
4x5gFOLDihydrofolate reductase1.5.1.30.441
1a4iNDPC-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.440
1b2rFADFerredoxin--NADP reductase1.18.1.20.440
1bmfADPATP synthase subunit alpha, mitochondrial/0.440
1bmfADPATP synthase subunit beta, mitochondrial3.6.3.140.440
1e79ADPATP synthase subunit alpha, mitochondrial/0.440
1e79ADPATP synthase subunit beta, mitochondrial3.6.3.140.440
1fdkGLEPhospholipase A23.1.1.40.440
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.440
1i5bANPChemotaxis protein CheA2.7.13.30.440
1i9qIOFCarbonic anhydrase 24.2.1.10.440
1kgqSCO2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase2.3.1.1170.440
1kp2ATPArgininosuccinate synthase6.3.4.50.440
1olsTDP2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.440
1opbRETRetinol-binding protein 2/0.440
1ra8FOLDihydrofolate reductase1.5.1.30.440
1w7h3IPMitogen-activated protein kinase 14/0.440
2ban357Gag-Pol polyprotein2.7.7.490.440
2bnsMSTReaction center protein L chain/0.440
2bzsCB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.440
2npfMOUElongation factor 2/0.440
2oadGTBGlutathione S-transferase P 12.5.1.180.440
2ociTYCValacyclovir hydrolase3.10.440
2rc4ACOHistone acetyltransferase KAT6A/0.440
2v2qNVG4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.440
2zruFMNIsopentenyl-diphosphate delta-isomerase/0.440
2zytPPSSulfotransferase 1 family member D1/0.440
3fpjSAMUncharacterized protein/0.440
3nl6TPSUncharacterized protein/0.440
3nu03TUDihydrofolate reductase1.5.1.30.440
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.440
4b6s2HN3-dehydroquinate dehydratase4.2.1.100.440
4br0AU1Ectonucleoside triphosphate diphosphohydrolase 2/0.440
4bz8J38Histone deacetylase/0.440
4ge5A89Tyrosine-protein phosphatase non-receptor type 93.1.3.480.440
4gevCB3Thymidylate synthase/0.440
4gi2NAPCrotonyl-CoA carboxylase/reductase/0.440
4gn8ASORegucalcin3.1.1.170.440
4i4b1CV3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.440
4q0kGA3Phytohormone-binding protein/0.440
4qfxDGTDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.440
4r1lADPPhenylacetate-coenzyme A ligase/0.440
4ts3FMCPurine nucleoside phosphorylase DeoD-type/0.440
4yddMD1DMSO reductase family type II enzyme, molybdopterin subunit/0.440
5c1gGDUHisto-blood group ABO system transferase/0.440
9mhtSAHModification methylase HhaI2.1.1.370.440