sc-PDB

List of CHEMBLId :

This value allows a number of roughly comparable measures of half-maximal response concentration/potency/affinity to be compared on a negative logarithmic scale (e.g., an IC50 measurement of 1nM would have a pChEMBL value of 9).

Uniprot Annotation

Name:	Geranylgeranyl transferase type-2 subunit beta
ID:	PGTB2_RAT
AC:	Q08603
Organism:	Rattus norvegicus
Reign:	Eukaryota
TaxID:	10116
EC Number:	2.5.1.60

---

Chains:

Chain Name:	Percentage of Residues within binding site
A	13 %
B	87 %

---

Ligand binding site composition:

B-Factor:	40.107
Number of residues:	32
Including
Standard Amino Acids:	30
Non Standard Amino Acids:	1
Water Molecules:	1
Cofactors:
Metals:	ZN

---

Cavity properties

Ligandability	Volume (Å3)
1.026	536.625

% Hydrophobic	% Polar
52.83	47.17
According to VolSite

HET Code:	7TP
Formula:	C33H32N4O6S
Molecular weight:	612.695 g/mol
DrugBank ID:	-
Buried Surface Area:	36.96 %
Polar Surface area:	126.49 Å2

Number of
H-Bond Acceptors:	7
H-Bond Donors:	1
Rings:	6
Aromatic rings:	5
Anionic atoms:	0
Cationic atoms:	0
Rule of Five Violation:	1
Rotatable Bonds:	9

---

Mass center Coordinates

X	Y	Z
3.76541	20.7385	27.7996

• 2D View
• 3D View