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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4dus0MPBeta-secretase 13.4.23.46

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
4dus0MPBeta-secretase 13.4.23.461.000
4ke11R6Beta-secretase 13.4.23.460.735
3qi1C6ABeta-secretase 13.4.23.460.643
4lxm1YUBeta-secretase 13.4.23.460.624
2f3eAXQBeta-secretase 13.4.23.460.623
4exg916Beta-secretase 13.4.23.460.623
2g94ZPQBeta-secretase 13.4.23.460.620
2hm1LIQBeta-secretase 13.4.23.460.620
3duyAFJBeta-secretase 13.4.23.460.616
3k5gBJCBeta-secretase 13.4.23.460.616
4ewo996Beta-secretase 13.4.23.460.614
4i0h1BLBeta-secretase 13.4.23.460.613
3k5c0BIBeta-secretase 13.4.23.460.612
3vf30GSBeta-secretase 13.4.23.460.607
3n4l842Beta-secretase 13.4.23.460.598
3dv5BAVBeta-secretase 13.4.23.460.597
4lxk1YTBeta-secretase 13.4.23.460.592
2p4j23IBeta-secretase 13.4.23.460.590
3dv1AR9Beta-secretase 13.4.23.460.589
4dpf0LGBeta-secretase 13.4.23.460.579
2fdpFRPBeta-secretase 13.4.23.460.576
3kmxG00Beta-secretase 13.4.23.460.576
3pi53P5Beta-secretase 13.4.23.460.571
3vg10GTBeta-secretase 13.4.23.460.571
4ke01R8Beta-secretase 13.4.23.460.567
2p83MR0Beta-secretase 13.4.23.460.565
2g1n1IGRenin3.4.23.150.563
3fktSIIBeta-secretase 13.4.23.460.562
2f3fAXFBeta-secretase 13.4.23.460.560
2vieVG0Beta-secretase 13.4.23.460.560
4djy0KRBeta-secretase 13.4.23.460.558
4i0j842Beta-secretase 13.4.23.460.558
4frkDWDBeta-secretase 13.4.23.460.557
4h3f10OBeta-secretase 13.4.23.460.557
3pwwROCEndothiapepsin3.4.23.220.555
3udn09BBeta-secretase 13.4.23.460.553
4dju0KKBeta-secretase 13.4.23.460.552
3ixk929Beta-secretase 13.4.23.460.547
3udk095Beta-secretase 13.4.23.460.547
4j1k1HGBeta-secretase 13.4.23.460.547
4l7g1W0Beta-secretase 13.4.23.460.547
1w6hTITPlasmepsin-23.4.23.390.545
4ha513WBeta-secretase 13.4.23.460.545
1lf2R37Plasmepsin-23.4.23.390.542
4i0f1BFBeta-secretase 13.4.23.460.542
4b1c1B1Beta-secretase 13.4.23.460.540
4h3j10WBeta-secretase 13.4.23.460.540
3ixj586Beta-secretase 13.4.23.460.539
4y35F90Endothiapepsin3.4.23.220.538
2g1s4IGRenin3.4.23.150.537
3l5dBDVBeta-secretase 13.4.23.460.536
3pmy41LEndothiapepsin3.4.23.220.536
4fs4H24Beta-secretase 13.4.23.460.536
3kmyD8YBeta-secretase 13.4.23.460.535
3pmuF7LEndothiapepsin3.4.23.220.535
4j0v1H7Beta-secretase 13.4.23.460.534
4fse0VABeta-secretase 13.4.23.460.533
4l7j1W2Beta-secretase 13.4.23.460.532
2vnmCM8Beta-secretase 13.4.23.460.531
2wf2ZY2Beta-secretase 13.4.23.460.528
3d91REMRenin3.4.23.150.528
3pldF90Endothiapepsin3.4.23.220.527
4h3i10VBeta-secretase 13.4.23.460.527
4i1c1BEBeta-secretase 13.4.23.460.527
3p62FMNPentaerythritol tetranitrate reductase/0.524
3t7x4SHEndothiapepsin3.4.23.220.524
4h1e10JBeta-secretase 13.4.23.460.524
4j0y1H6Beta-secretase 13.4.23.460.523
3t7qRB4Endothiapepsin3.4.23.220.522
3h3r14HCollagen type IV alpha-3-binding protein/0.520
4y3qF02Endothiapepsin3.4.23.220.520
4j1c1HOBeta-secretase 13.4.23.460.518
1e800GQEndothiapepsin3.4.23.220.517
1f20FADNitric oxide synthase, brain1.14.13.390.517
3udj092Beta-secretase 13.4.23.460.516
2of0CMZBeta-secretase 13.4.23.460.515
1vi2NADQuinate/shikimate dehydrogenase/0.513
1e81M91Endothiapepsin3.4.23.220.512
2v00V15Endothiapepsin3.4.23.220.512
3r2fPB0Beta-secretase 13.4.23.460.512
4bekXK0Beta-secretase 13.4.23.460.512
4y380A9Endothiapepsin3.4.23.220.512
1gvw0EMEndothiapepsin3.4.23.220.511
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.511
3psyRB9Endothiapepsin3.4.23.220.511
3qbhQBHBeta-secretase 13.4.23.460.511
3vyfVYFRenin3.4.23.150.509
1lf3EH5Plasmepsin-23.4.23.390.506
4azy7F3Beta-secretase 13.4.23.460.506
2dsgSAHDiphthine synthase/0.505
3own3OXRenin3.4.23.150.505
4b78KGGBeta-secretase 13.4.23.460.505
4y4jLNREndothiapepsin3.4.23.220.505
1zapA70Candidapepsin-23.4.23.240.504
4zeaIMIEndothiapepsin3.4.23.220.504
1g63FMNEpidermin decarboxylase4.1.10.503
2qzlIXSBeta-secretase 13.4.23.460.503
3s87ADPRibonucleoside-diphosphate reductase large chain 11.17.4.10.503
4b4vL34Bifunctional protein FolD/0.503
2il2LIXRenin3.4.23.150.502
3vucHHERenin3.4.23.150.501
1fw0KAIGlutamate receptor 2/0.499
1rszDIHPurine nucleoside phosphorylase2.4.2.10.498
3t4eNADQuinate/shikimate dehydrogenase/0.498
4dptAGSMevalonate diphosphate decarboxylase/0.498
4ejmNAPPutative zinc-binding dehydrogenase/0.498
1psa0ZLPepsin A3.4.23.10.497
3h0bB35Beta-secretase 13.4.23.460.497
3zovWZVBeta-secretase 13.4.23.460.497
4fm80UQBeta-secretase 13.4.23.460.497
1xe65FPPlasmepsin-23.4.23.390.496
3pbzF02Endothiapepsin3.4.23.220.496
4a862ANMajor pollen allergen Bet v 1-A/0.496
2dgnDOIAdenylosuccinate synthetase isozyme 1/0.495
3f03FMNPentaerythritol tetranitrate reductase/0.495
1cs4FOKAdenylate cyclase type 2/0.494
1cs4FOKAdenylate cyclase type 5/0.494
2owuSAHDiphthine synthase/0.494
2q153MRBeta-secretase 13.4.23.460.494
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.494
4b00I6XBeta-secretase 13.4.23.460.494
4i0z1BBBeta-secretase 13.4.23.460.494
3vswR31Renin3.4.23.150.493
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.493
2ed3SAHDiphthine synthase/0.492
2g20L1ARenin3.4.23.150.492
2p8hMY9Beta-secretase 13.4.23.460.492
3c15FOKAdenylate cyclase type 2/0.492
3c15FOKAdenylate cyclase type 5/0.492
3h3t16HCollagen type IV alpha-3-binding protein/0.492
2rlcCHDCholoylglycine hydrolase3.5.1.240.491
4djw0KPBeta-secretase 13.4.23.460.491
1me6IVSPlasmepsin-23.4.23.390.490
2b8l5HABeta-secretase 13.4.23.460.490
3qemQEMGlutamate receptor ionotropic, NMDA 2B/0.490
3qemQEMNMDA glutamate receptor subunit/0.490
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.489
2a5kAZPReplicase polyprotein 1ab3.4.220.489
3a0tADPSensor histidine kinase/0.489
3h3sH15Collagen type IV alpha-3-binding protein/0.489
3q70RITCandidapepsin-23.4.23.240.489
3zknWZVBeta-secretase 23.4.23.450.489
5c1d12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.489
1eagA70Candidapepsin-23.4.23.240.488
3prsRITEndothiapepsin3.4.23.220.488
4djv0KMBeta-secretase 13.4.23.460.488
1ppkIVVPenicillopepsin-13.4.23.200.487
2dxvSAHDiphthine synthase/0.487
4bf9FMNtRNA-dihydrouridine(16) synthase/0.487
5einNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.487
5fwnNAPPutative dehydrogenase/0.487
1dg7WRBDihydrofolate reductase1.5.1.30.486
2g247IGRenin3.4.23.150.486
3bugAEHBeta-secretase 13.4.23.460.486
3qwpSAMHistone-lysine N-methyltransferase SMYD32.1.1.430.486
3rviRVIBeta-secretase 13.4.23.460.486
2pksG44Prothrombin3.4.21.50.485
3rsv3RSBeta-secretase 13.4.23.460.485
4a86H35Major pollen allergen Bet v 1-A/0.485
4a8v2ANMajor pollen allergen Bet v 1-J/0.485
4j0p1H8Beta-secretase 13.4.23.460.485
2gnaGDUUDP-N-acetylglucosamine 4,6-dehydratase (inverting)4.2.1.1150.484
3n0hTOPDihydrofolate reductase1.5.1.30.484
3pchCHBProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.484
4k6fNAPPutative Acetoacetyl-CoA reductase/0.484
1culFOKAdenylate cyclase type 2/0.483
1culFOKAdenylate cyclase type 5/0.483
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.483
2e8qSAHDiphthine synthase/0.483
3kdb006Gag-Pol polyprotein3.4.23.160.483
1xddAAYIntegrin alpha-L/0.482
2q46NAPUncharacterized protein At5g02240/0.482
2webPP4Penicillopepsin-13.4.23.200.482
4kugNAD3-hydroxybutyryl-CoA dehydrogenase/0.482
2bb3SAHCobalamin biosynthesis precorrin-6Y methylase (CbiE)/0.481
2e8hSAHDiphthine synthase/0.481
3rthRTHBeta-secretase 13.4.23.460.481
3tqxPLP2-amino-3-ketobutyrate coenzyme A ligase/0.481
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.481
1cjkFOKAdenylate cyclase type 2/0.480
1cjkFOKAdenylate cyclase type 5/0.480
1drhNAPDihydrofolate reductase1.5.1.30.480
1gvt2ZSEndothiapepsin3.4.23.220.480
1ppl1Z7Penicillopepsin-13.4.23.200.480
1xs4DCPdCTP deaminase/0.480
2eh5SAHDiphthine synthase/0.480
2va6H24Beta-secretase 13.4.23.460.480
3fp0FP015-O-acetyltransferase/0.480
3orfNADDihydropteridine reductase1.5.1.340.480
3wb40B3Beta-secretase 13.4.23.460.480
4i101BSBeta-secretase 13.4.23.460.480
1od10QSEndothiapepsin3.4.23.220.479
2g1o2IGRenin3.4.23.150.479
2i4qUA4Renin3.4.23.150.479
1a9yUPGUDP-glucose 4-epimerase5.1.3.20.478
1jg0DDTThymidylate synthase/0.478
1umkFADNADH-cytochrome b5 reductase 31.6.2.20.478
1xe55FEPlasmepsin-23.4.23.390.478
2egbSAHDiphthine synthase/0.478
3awhFMNFMN-binding protein/0.478
3h3qH13Collagen type IV alpha-3-binding protein/0.478
3pllF06Endothiapepsin3.4.23.220.478
3s3vTOPDihydrofolate reductase1.5.1.30.478
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.478
2ed5SAHDiphthine synthase/0.477
2fy4COACholine O-acetyltransferase2.3.1.60.477
2pcaSAHDiphthine synthase/0.477
3t64DU3Deoxyuridine 5'-triphosphate nucleotidohydrolase/0.477
4fsl0VBBeta-secretase 13.4.23.460.477
1gvv0GMEndothiapepsin3.4.23.220.476
1toiHCIAspartate aminotransferase2.6.1.10.476
1ykdCMPAdenylate cyclase/0.476
2dxwSAHDiphthine synthase/0.476
3t6iNC9Endothiapepsin3.4.23.220.476
3vqsJT1Genome polyprotein/0.476
4a83DXCMajor pollen allergen Bet v 1-A/0.476
4frs0V6Beta-secretase 13.4.23.460.476
1bil0IURenin3.4.23.150.475
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.475
1cjuFOKAdenylate cyclase type 2/0.475
1cjuFOKAdenylate cyclase type 5/0.475
1h63FMNPentaerythritol tetranitrate reductase/0.475
2hr8SAHDiphthine synthase/0.475
3i6qNDPPutative leucoanthocyanidin reductase 1/0.475
3lnc5GPGuanylate kinase/0.475
3rbaCODPhosphopantetheine adenylyltransferase/0.475
4tkg09LTankyrase-22.4.2.300.475
4yd7F5NEndothiapepsin3.4.23.220.475
5dmhADP3-oxo-tetronate kinase/0.475
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.474
1tj0FADBifunctional protein PutA1.5.5.20.474
1x27ASP_TYR_VAL_HIS_PTRTyrosine-protein kinase Lck2.7.10.20.474
2ohm8APBeta-secretase 13.4.23.460.474
3ekuCY9Actin-5C/0.474
4m83ERYOleandomycin glycosyltransferase2.4.10.474
4q0kGA3Phytohormone-binding protein/0.474
4yp5NAPNicotinamide-nucleotide adenylyltransferase2.7.7.10.474
1mvtDTMDihydrofolate reductase1.5.1.30.473
1o9bNAIQuinate/shikimate dehydrogenase/0.473
1rfuADPPyridoxal kinase2.7.1.350.473
1rzuADPGlycogen synthase 12.4.1.210.473
1s3uTQDDihydrofolate reductase1.5.1.30.473
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.473
1tojHCIAspartate aminotransferase2.6.1.10.473
2dv7SAHDiphthine synthase/0.473
3zeiAWHO-acetylserine sulfhydrylase/0.473
4xbfFADLysine-specific histone demethylase 1A10.473
4yfy1YJVioF/0.473
1hdgNADGlyceraldehyde-3-phosphate dehydrogenase/0.472
1vzeCB3Thymidylate synthase/0.472
2g226IGRenin3.4.23.150.472
2os1BB2Peptide deformylase/0.472
4lol1YEStimulator of interferon genes protein/0.472
5kf1COAPredicted acetyltransferase/0.472
1ndhFADNADH-cytochrome b5 reductase 31.6.2.20.471
1qy5NECEndoplasmin/0.471
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.471
2jjj0QSEndothiapepsin3.4.23.220.471
2rqfJH3Hemolymph juvenile hormone binding protein/0.471
2vwqNAPGlucose 1-dehydrogenase/0.471
2xupTZ5Acetylcholinesterase3.1.1.70.471
3a6rFMNFMN-binding protein/0.471
3elbC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.471
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.471
3p67FMNPentaerythritol tetranitrate reductase/0.471
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.470
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.470
1rneC60Renin3.4.23.150.470
1v5z2HCMajor NAD(P)H-flavin oxidoreductase1.6.990.470
2hfuMEVMevalonate kinase/0.470
3gfbNADL-threonine 3-dehydrogenase/0.470
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.470
3o7bSAHRibosomal RNA small subunit methyltransferase Nep1/0.470
3pb5F63Endothiapepsin3.4.23.220.470
4b4w9L9Bifunctional protein FolD/0.470
4bj9UHBTankyrase-22.4.2.300.470
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.470
1a9zUPGUDP-glucose 4-epimerase5.1.3.20.469
1b2lNDCAlcohol dehydrogenase1.1.1.10.469
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.469
1p5rCOAFormyl-CoA:oxalate CoA-transferase/0.469
2ol0DUDDUTP pyrophosphatase/0.469
3u8l09QAcetylcholine-binding protein/0.469
3vy2FMNFMN-binding protein/0.469
4dreNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.469
4g95OAGDihydrofolate reductase1.5.1.30.469
4j0z1H5Beta-secretase 13.4.23.460.469
4n5nNAPAcetoacetyl-CoA reductase1.1.1.360.469
4r1fADPDNA topoisomerase 2-alpha5.99.1.30.469
1e82M90Endothiapepsin3.4.23.220.468
1j78VDYVitamin D-binding protein/0.468
2abbFMNPentaerythritol tetranitrate reductase/0.468
2b37NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.468
2p9dSAHDiphthine synthase/0.468
2y99NADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase1.3.1.560.468
3kn03TOBeta-secretase 13.4.23.460.468
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.467
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.467
1u0hFOKAdenylate cyclase type 2/0.467
1u0hFOKAdenylate cyclase type 5/0.467
2a9y26AAdenosine kinase2.7.1.200.467
2h4nAZMCarbonic anhydrase 24.2.1.10.467
2irzI02Beta-secretase 13.4.23.460.467
2iyfERYOleandomycin glycosyltransferase2.4.10.467
2pcmSAHDiphthine synthase/0.467
3ndcSAHPrecorrin-4 C(11)-methyltransferase2.1.1.1330.467
4a99FADTetX family tetracycline inactivation enzyme/0.467
1y7lASN_LEU_ASN_ILECysteine synthase2.5.1.470.466
2bgiFADNADPH:ferredoxin reductase/0.466
2el0SAHDiphthine synthase/0.466
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.466
2v7qATPATP synthase subunit alpha, mitochondrial/0.466
2v7qATPATP synthase subunit beta, mitochondrial3.6.3.140.466
3adaNADSubunit alpha of sarocosine oxidase/0.466
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.466
4f1yCNIGlutamate receptor 3/0.466
4hdbG52Gag-Pol polyprotein3.4.23.160.466
1p0ySAHRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic2.1.1.1270.465
1tl7FOKAdenylate cyclase type 2/0.465
1tl7FOKAdenylate cyclase type 5/0.465
1w51L01Beta-secretase 13.4.23.460.465
2pchSAHDiphthine synthase/0.465
2zbaZBATrichothecene 3-O-acetyltransferase/0.465
2ztsADPUncharacterized protein/0.465
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.465
3friSAH16S rRNA methylase/0.465
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.465
4d89BXDBeta-secretase 13.4.23.460.465
1bmfANPATP synthase subunit alpha, mitochondrial/0.464
1bmfANPATP synthase subunit beta, mitochondrial3.6.3.140.464
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.464
1vf2GTXGlutathione S-transferase 32.5.1.180.464
2dv5SAHDiphthine synthase/0.464
3eheNADUDP-glucose 4-epimerase (GalE-1)/0.464
3hziATPSerine/threonine-protein kinase toxin HipA/0.464
3juqAJDPhenazine biosynthesis protein A/B/0.464
3rtnRTNBeta-secretase 13.4.23.460.464
4a87NARMajor pollen allergen Bet v 1-A/0.464
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.464
4pleCPSNuclear receptor subfamily 5 group A member 2/0.464
5a88ADPRiboflavin biosynthesis protein RibF2.7.1.260.464
1i7pFADNADH-cytochrome b5 reductase 31.6.2.20.463
1pd9CO4Dihydrofolate reductase1.5.1.30.463
1zxnADPDNA topoisomerase 2-alpha5.99.1.30.463
2af3COAPhosphate acetyltransferase2.3.1.80.463
2dekSAHDiphthine synthase/0.463
2dv4SAHDiphthine synthase/0.463
2fn7NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.463
2gvdFKPAdenylate cyclase type 2/0.463
2gvdFKPAdenylate cyclase type 5/0.463
2lfoGCHFatty acid-binding protein, liver/0.463
3d84NDPDihydrofolate reductase1.5.1.30.463
3hucG97Mitogen-activated protein kinase 14/0.463
3ld6BCDLanosterol 14-alpha demethylase1.14.13.700.463
3tozNADShikimate dehydrogenase (NADP(+))/0.463
4a61ANPPlasmid segregation protein ParM/0.463
4f31KAIGlutamate receptor 3/0.463
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.463
4hzt0ZABeta-secretase 13.4.23.460.463
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.463
5bu2ADPUncharacterized protein/0.463
1cnfFADNitrate reductase [NADH]1.7.1.10.462
1lceTMFThymidylate synthase/0.462
2aq7TL53-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.462
2cndFADNitrate reductase [NADH]1.7.1.10.462
2g1y5IGRenin3.4.23.150.462
2hk9NAPShikimate dehydrogenase (NADP(+))/0.462
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.462
3a20FMNFMN-binding protein/0.462
3e3uNVCPeptide deformylase3.5.1.880.462
3fr5I4AFatty acid-binding protein, adipocyte/0.462
3gy9COAGCN5-related N-acetyltransferase/0.462
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.462
3r5yF42Uncharacterized protein/0.462
4ek1CAMCamphor 5-monooxygenase1.14.15.10.462
4lopSB4Mitogen-activated protein kinase 14/0.462
4xq6FMNDihydroorotate dehydrogenase (quinone)/0.462
1mewXMPInosine-5'-monophosphate dehydrogenase/0.461
1py5PY1TGF-beta receptor type-12.7.11.300.461
1xz85GPBifunctional protein PyrR2.4.2.90.461
2e17SAHDiphthine synthase/0.461
2hutSAHDiphthine synthase/0.461
2wedPP6Penicillopepsin-13.4.23.200.461
3ibqATPPyridoxal kinase/0.461
3maaFKPAdenylate cyclase type 2/0.461
3maaFKPAdenylate cyclase type 5/0.461
3oqfS51Renin3.4.23.150.461
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.461
4m4922YL-lactate dehydrogenase A chain1.1.1.270.461
4y3zF41Endothiapepsin3.4.23.220.461
1e79ATPATP synthase subunit alpha, mitochondrial/0.460
1e79ATPATP synthase subunit beta, mitochondrial3.6.3.140.460
1j9zFADNADPH--cytochrome P450 reductase/0.460
1kvsUPGUDP-glucose 4-epimerase5.1.3.20.460
1rc4DDFDihydrofolate reductase1.5.1.30.460
1youPFDCollagenase 33.4.240.460
2ahvCOAAcetate CoA-transferase YdiF2.8.3.80.460
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.460
2egsSAHDiphthine synthase/0.460
2emrSAHDiphthine synthase/0.460
2ptfFMNUncharacterized protein MTH_863/0.460
2vttLZDCyclin-dependent kinase 22.7.11.220.460
3c14FOKAdenylate cyclase type 2/0.460
3c14FOKAdenylate cyclase type 5/0.460
3g2lLEWGlycogen phosphorylase, muscle form2.4.1.10.460
3ho2N323-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.460
3nn6HNK6-hydroxy-L-nicotine oxidase/0.460
3p0hFSEPutative tyrosyl-tRNA synthetase/0.460
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.460
4g8jTHMUridine phosphorylase/0.460
4j49NAIUncharacterized protein/0.460
4jlm1NNDeoxycytidine kinase2.7.1.740.460
4q71FADBifunctional protein PutA/0.460
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.460
3vw7VPXProteinase-activated receptor 1/0.460
1mvsDTMDihydrofolate reductase1.5.1.30.459
1x1cSAHC-20 methyltransferase/0.459
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.459
2cftPLPPyridoxal phosphate phosphatase/0.459
2emuSAHDiphthine synthase/0.459
2flhZEACytokinin-specific binding protein/0.459
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.459
2g263LGRenin3.4.23.150.459
2g274LGRenin3.4.23.150.459
2hg1N5OEndoplasmin/0.459
2rhgIGPTryptophan synthase alpha chain/0.459
2zjnF1NBeta-secretase 13.4.23.460.459
3eksCY9Actin-5C/0.459
3i12ADPD-alanine--D-alanine ligase A6.3.2.40.459
3livE16Protease/0.459
3mt817TGlycogen phosphorylase, muscle form2.4.1.10.459
4f9gC2EStimulator of interferon genes protein/0.459
4fco0U4Beta-secretase 13.4.23.460.459
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.459
4loi1YCStimulator of interferon genes protein/0.459
1bwlFMNNADPH dehydrogenase 11.6.99.10.458
1ju9NADAlcohol dehydrogenase E chain1.1.1.10.458
2ab8MTPAdenosine kinase2.7.1.200.458
2bjuIH4Plasmepsin-23.4.23.390.458
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.458
2ejzSAHDiphthine synthase/0.458
2fy5SOPCholine O-acetyltransferase2.3.1.60.458
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.458
2huvSAHDiphthine synthase/0.458
2poqISDTrans-1,2-dihydrobenzene-1,2-diol dehydrogenase1.3.1.200.458
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.458
3a3yOBNSodium/potassium-transporting ATPase subunit alpha/0.458
3imgBZ3Pantothenate synthetase6.3.2.10.458
3mjrAC2Deoxycytidine kinase2.7.1.740.458
3otfCMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4/0.458
3t7p7SPEndothiapepsin3.4.23.220.458
3w8dNAD3-hydroxybutyrate dehydrogenase/0.458
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.458
4fdaNAP3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.458
4i1nFOLDihydrofolate reductase1.5.1.30.458
1hdrNADDihydropteridine reductase1.5.1.340.457
1l5oNCNNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.457
2c29NAPDihydroflavonol 4-reductase/0.457
2ea2F77Methionine aminopeptidase 2/0.457
2gjlFMNNitronate monooxygenase1.13.12.160.457
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.457
3a6qFMNFMN-binding protein/0.457
3cppCAMCamphor 5-monooxygenase1.14.15.10.457
3p84FMNPentaerythritol tetranitrate reductase/0.457
3phiNDPShikimate dehydrogenase (NADP(+))/0.457
3wv9FEGHmd co-occurring protein HcgE/0.457
3zlq6T9Beta-secretase 23.4.23.450.457
4cr8NADN-acylmannosamine 1-dehydrogenase1.1.1.2330.457
4dbzNDPPutative ketoacyl reductase1.3.10.457
4i8x6P3L-lactate dehydrogenase A chain1.1.1.270.457
4m52FADDihydrolipoyl dehydrogenase1.8.1.40.457
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.457
4nd4NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.457
1cjvFOKAdenylate cyclase type 2/0.456
1cjvFOKAdenylate cyclase type 5/0.456
1kvuUPGUDP-glucose 4-epimerase5.1.3.20.456
1m4dCOAAminoglycoside 2'-N-acetyltransferase2.3.10.456
1mb4NDPAspartate-semialdehyde dehydrogenase 1/0.456
1pvgANPDNA topoisomerase 25.99.1.30.456
1ra3MTXDihydrofolate reductase1.5.1.30.456
2ylzFADPhenylacetone monooxygenase1.14.13.920.456
2zjuIM4Acetylcholine-binding protein/0.456
3atzFMNProstaglandin F2a synthase/0.456
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.456
3gwfNAPCyclohexanone monooxygenase/0.456
3ii43IIDihydrolipoyl dehydrogenase1.8.1.40.456
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.456
3o0oGDPVitamin B12-dependent ribonucleotide reductase/0.456
3ojiPYVAbscisic acid receptor PYL3/0.456
3p8jFMNPentaerythritol tetranitrate reductase/0.456
3t6iNC8Endothiapepsin3.4.23.220.456
4b1rITCTetracycline repressor protein class D/0.456
4isg1FYGlucokinase2.7.1.20.456
4jlk1NODeoxycytidine kinase2.7.1.740.456
4k28NADShikimate dehydrogenase family protein/0.456
5bnw12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.456
1c4vIH2Prothrombin3.4.21.50.455
1cbfSAHCobalt-precorrin-4 C(11)-methyltransferase2.1.1.2710.455
1cjtFOKAdenylate cyclase type 2/0.455
1cjtFOKAdenylate cyclase type 5/0.455
1cjwCOTSerotonin N-acetyltransferase/0.455
1g54FFBCarbonic anhydrase 24.2.1.10.455
1ia1NDPDihydrofolate reductase1.5.1.30.455
1jdzFMBPurine nucleoside phosphorylase/0.455
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.455
1t7o152Carnitine O-acetyltransferase2.3.1.70.455
1udaUFGUDP-glucose 4-epimerase5.1.3.20.455
1xvaSAMGlycine N-methyltransferase2.1.1.200.455
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.455
2b8v3BNBeta-secretase 13.4.23.460.455
2cy0NAPShikimate dehydrogenase (NADP(+))/0.455
2wi6ZZ6Heat shock protein HSP 90-alpha/0.455
2xncFADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.455
3aivHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic3.2.1.1820.455
3c16FOKAdenylate cyclase type 2/0.455
3c16FOKAdenylate cyclase type 5/0.455
3c6n2S8Protein TRANSPORT INHIBITOR RESPONSE 1/0.455
3g0yP9A3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.455
3kqjUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.455
3m6pBB2Peptide deformylase 1B, chloroplastic/mitochondrial3.5.1.880.455
3oeyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
3otwCOAPhosphopantetheine adenylyltransferase/0.455
3pgiF41Endothiapepsin3.4.23.220.455
3ssmSAHMycinamicin VI 2''-O-methyltransferase/0.455
4f3gKAIGlutamate receptor 3/0.455
4pnrG18Tankyrase-22.4.2.300.455
5cp4CAMCamphor 5-monooxygenase1.14.15.10.455
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.454
1c70L75Protease/0.454
1ci7UMPThymidylate synthase2.1.1.450.454
1dhfFOLDihydrofolate reductase1.5.1.30.454
1h50FMNPentaerythritol tetranitrate reductase/0.454
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.454
1s20NAD2,3-diketo-L-gulonate reductase1.1.1.1300.454
1t4cCOAFormyl-CoA:oxalate CoA-transferase/0.454
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
1ykfNAPNADP-dependent isopropanol dehydrogenase1.1.1.800.454
1zdwFLVPrenyltransferase/0.454
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
2h21SAMRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic2.1.1.1270.454
2huxSAHDiphthine synthase/0.454
2ovhAS0Progesterone receptor/0.454
3h8bNSYCathepsin L13.4.22.150.454
3i8p8403-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.454
3l5bBDOBeta-secretase 13.4.23.460.454
3nutSAHPrecorrin-3 methylase/0.454
3oafOAGDihydrofolate reductase1.5.1.30.454
3rh7FMNUncharacterized protein/0.454
3t2vKKJPeptidoglycan recognition protein 1/0.454
3zksWZVBeta-secretase 23.4.23.450.454
4a7b3W5Collagenase 33.4.240.454
4lxa1YSBeta-secretase 13.4.23.460.454
4nmbFADBifunctional protein PutA/0.454
4nv1TYDFormyl transferase/0.454
4psbGA3Cytokinin-specific binding protein/0.454
5esdTDP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.454
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.454
1hfqMOTDihydrofolate reductase1.5.1.30.453
1kw9BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.453
1sbrVIBPutative HMP/thiamine-binding protein YkoF/0.453
2aaxPDNMineralocorticoid receptor/0.453
2hekGDPUncharacterized protein/0.453
2p6lSAHDiphthine synthase/0.453
2uxoTACHTH-type transcriptional regulator TtgR/0.453
3drcMTXDihydrofolate reductase1.5.1.30.453
3ig6438Urokinase-type plasminogen activator3.4.21.730.453
3junAKDPhenazine biosynthesis protein A/B/0.453
3jyqNADQuinate/shikimate dehydrogenase (NAD(+))/0.453
3ox34X4Ribosyldihydronicotinamide dehydrogenase [quinone]/0.453
4b67FADL-ornithine N(5)-monooxygenase/0.453
4dd8BATDisintegrin and metalloproteinase domain-containing protein 83.4.240.453
4e2wJHZMethyltransferase/0.453
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.453
4rtbSAMPutative thiazole biosynthesis protein ThiH/0.453
4y45F91Endothiapepsin3.4.23.220.453
7stdCRPScytalone dehydratase4.2.1.940.453
1b5eDCMDeoxycytidylate 5-hydroxymethyltransferase2.1.2.80.452
1dirNADDihydropteridine reductase1.5.1.340.452
1m78NDPDihydrofolate reductase1.5.1.30.452
1npdNADQuinate/shikimate dehydrogenase/0.452
1pjcNADAlanine dehydrogenase/0.452
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.452
2dg4RAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.452
2v16C47Renin3.4.23.150.452
2y1tDUDSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.452
3dm6757Beta-secretase 13.4.23.460.452
3fwiCAMCamphor 5-monooxygenase1.14.15.10.452
3kjm245Cytokinin dehydrogenase 11.5.99.120.452
3oiaA31Camphor 5-monooxygenase1.14.15.10.452
3q8uADPNucleoside diphosphate kinase/0.452
3rk1ATPN-type ATP pyrophosphatase superfamily/0.452
4dymIYZActivin receptor type-12.7.11.300.452
4fk8FADFerredoxin--NADP reductase/0.452
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.452
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.452
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.452
4tqgNDPPutative dTDP-d-glucose 4 6-dehydratase/0.452
4yfy0FXVioF/0.452
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.452
1a7xFKAPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.451
1dyiFOLDihydrofolate reductase1.5.1.30.451
1ee9NADMethylenetetrahydrofolate dehydrogenase [NAD(+)]1.5.1.150.451
1f8fNADBenzyl alcohol dehydrogenase/0.451
1fm4DXCMajor pollen allergen Bet v 1-L/0.451
1hquHBYGag-Pol polyprotein2.7.7.490.451
1ikiREYD-alanyl-D-alanine carboxypeptidase3.4.16.40.451
1ix1BB2Peptide deformylase/0.451
1lvu9PPPurine nucleoside phosphorylase2.4.2.10.451
1vceSAHDiphthine synthase/0.451
2ag1TPPBenzaldehyde lyase/0.451
2eleSAHDiphthine synthase/0.451
2ie0ZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
2owvSAHDiphthine synthase/0.451
2rh9IGPTryptophan synthase alpha chain/0.451
3a3bRBFLumazine protein/0.451
3axkNDPRibulose bisphosphate carboxylase large chain4.1.1.390.451
3lqsPSZD-alanine aminotransferase2.6.1.210.451
3pl8FADPyranose 2-oxidase/0.451
3q9bB3NAcetylpolyamine amidohydrolase/0.451
3w77FMNFMN-dependent NADH-azoreductase/0.451
4a84DXCMajor pollen allergen Bet v 1-A/0.451
4d9t0JGRibosomal protein S6 kinase alpha-32.7.11.10.451
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.451
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
4kbyC2EStimulator of interferon genes protein/0.451
4m6jNDPDihydrofolate reductase1.5.1.30.451
4nd2A3DLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.451
4wdfA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.451
4yp6NAPNicotinamide-nucleotide adenylyltransferase2.7.7.10.451
5czySAMEukaryotic huntingtin interacting protein B/0.451
1bxqPP8Penicillopepsin-13.4.23.200.450
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.450
1j4hSUBPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.450
1jhaAAMNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.450
1l4eRBZNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.450
1q6yCOAFormyl-CoA:oxalate CoA-transferase/0.450
1snfUMPDeoxyuridine 5'-triphosphate nucleotidohydrolase3.6.1.230.450
1vbiNADMalate/L-lactate dehydrogenase family protein/0.450
1xelUPGUDP-glucose 4-epimerase5.1.3.20.450
2b4rNADGlyceraldehyde-3-phosphate dehydrogenase/0.450
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.450
2ehlSAHDiphthine synthase/0.450
2eldSAHDiphthine synthase/0.450
2ewvADPTwitching motility protein PilT/0.450
2fde385Gag-Pol polyprotein3.4.23.160.450
2fieA74Fructose-1,6-bisphosphatase 13.1.3.110.450
2fs4PZ1Renin3.4.23.150.450
2ga2A19Methionine aminopeptidase 2/0.450
2ofiADK3-methyladenine DNA glycosylase I/0.450
2ohuIP7Beta-secretase 13.4.23.460.450
2q1tNADPutative nucleotide sugar epimerase/ dehydratase/0.450
2qblCAMCamphor 5-monooxygenase1.14.15.10.450
3c1kT15Prothrombin3.4.21.50.450
3eluSAMMethyltransferase/0.450
3gbuATPUncharacterized sugar kinase PH14592.7.10.450
3gvhNADMalate dehydrogenase/0.450
3ixp834Ecdysone receptor/0.450
3lqfNADGalactitol dehydrogenase/0.450
3so9017Pol protein/0.450
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.450
3vv8B02Beta-secretase 13.4.23.460.450
3zgl10E4-hydroxy-3-methylbut-2-enyl diphosphate reductase/0.450
4b0532DBeta-secretase 13.4.23.460.450
4ef4C2EStimulator of interferon genes protein/0.450
4mleVO1Glucokinase2.7.1.20.450
4msg2C6Tankyrase-12.4.2.300.450
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.450
4obuPLPPyridoxal-dependent decarboxylase domain protein/0.450
5a1tNAIL-lactate dehydrogenase/0.450
5ex0SAHHistone-lysine N-methyltransferase SMYD32.1.1.430.450
4zj8SUVOrexin receptor type 1/0.450
1a4lDCFAdenosine deaminase3.5.4.40.449
1d0lBLGMembrane-bound lytic murein transglycosylase B4.2.2.n10.449
1foaUD1Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase2.4.1.1010.449
1mlvSAHRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic2.1.1.1270.449
1phePIYCamphor 5-monooxygenase1.14.15.10.449
1pkvRBFRiboflavin synthase2.5.1.90.449
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.449
1rkwPNTHTH-type transcriptional regulator QacR/0.449
1ulbGUNPurine nucleoside phosphorylase2.4.2.10.449
1ywgNADGlyceraldehyde-3-phosphate dehydrogenase/0.449
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.449
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.449
2b4rAESGlyceraldehyde-3-phosphate dehydrogenase/0.449
2ev9NAPShikimate dehydrogenase (NADP(+))/0.449
2j2pSC2Ficolin-2/0.449
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.449
2xhtC0YHeat shock protein HSP 90-alpha/0.449
2zsiGA4Gibberellin receptor GID1A30.449
3co93MSGenome polyprotein2.7.7.480.449
3dgaUMPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.449
3gqvNAPEnoyl reductase LovC10.449
3lfm3DTAlpha-ketoglutarate-dependent dioxygenase FTO/0.449
3mneDEXGlucocorticoid receptor/0.449
3pn4BB2Peptide deformylase 1B, chloroplastic/mitochondrial3.5.1.880.449
3qj0QI3Botulinum neurotoxin type A3.4.24.690.449
3r9uFADThioredoxin reductase/0.449
3ziuLSSLeucyl-tRNA synthetase/0.449
3zraORBProgesterone receptor/0.449
4c1fX8ZMetallo-beta-lactamase type 2/0.449
4i13FOLDihydrofolate reductase1.5.1.30.449
4j491J1Uncharacterized protein/0.449
4jbtASDCytochrome P450 monooxygenase/0.449
4wfr2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.449
4xymCOAAcyl-CoA synthetase (NDP forming)/0.449
4ypeSAMHistone-lysine N-methyltransferase ASH1L2.1.1.430.449
4z0g5GPInosine-5'-monophosphate dehydrogenase/0.449
4z4pSAHHistone-lysine N-methyltransferase 2D2.1.1.430.449
1cqp803Integrin alpha-L/0.448
1fkbRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.448
1k7fIAVTryptophan synthase alpha chain/0.448
1mu8CDBProthrombin3.4.21.50.448
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.448
1sezOMNProtoporphyrinogen oxidase, mitochondrial1.3.3.40.448
1t87CAMCamphor 5-monooxygenase1.14.15.10.448
1yqzCOACoenzyme A disulfide reductase/0.448
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.448
2e07SAHDiphthine synthase/0.448
2eglSAHDiphthine synthase/0.448
2ek2SAHDiphthine synthase/0.448
2h2eSA8Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic2.1.1.1270.448
2h9iEADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
2i51FMNPyridoxamine 5'-phosphate oxidase-related, FMN-binding/0.448
2nr4FMNConserved protein/0.448
2ph6712Beta-secretase 13.4.23.460.448
2w3bNDPDihydrofolate reductase1.5.1.30.448
2ydbNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.448
2z54AB1Gag-Pol polyprotein3.4.23.160.448
2z6rSAHDiphthine synthase/0.448
2zcvNDPQuinone oxidoreductase 21.6.5.20.448
3c35KAIGlutamate receptor ionotropic, kainate 1/0.448
3flsFLSMitogen-activated protein kinase 14/0.448
3gyaCOAGCN5-related N-acetyltransferase/0.448
3lcjCOAPhosphopantetheine adenylyltransferase/0.448
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
3pi0F91Endothiapepsin3.4.23.220.448
3qge26FGenome polyprotein2.7.7.480.448
3vf60H6Glucokinase2.7.1.20.448
3vydVYDRenin3.4.23.150.448
4fhd0TTSpore photoproduct lyase/0.448
4k6i9RARetinoic acid receptor RXR-alpha/0.448
4k9oTPPBenzoylformate decarboxylase4.1.1.70.448
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.448
4qxp1YEStimulator of interferon genes protein/0.448
4u0oMTALipoyl synthase 2/0.448
3sn6P0GBeta-2 adrenergic receptor/0.448
1adfTADAlcohol dehydrogenase E chain1.1.1.10.447
1bl4AP1Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.447
1drfFOLDihydrofolate reductase1.5.1.30.447
1e1mNAPNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.447
1e1qANPATP synthase subunit alpha, mitochondrial/0.447
1e1qANPATP synthase subunit beta, mitochondrial3.6.3.140.447
1fwkADPHomoserine kinase2.7.1.390.447
1kbiFMNCytochrome b2, mitochondrial1.1.2.30.447
1khrVIRStreptogramin A acetyltransferase2.3.10.447
1kvkATPMevalonate kinase2.7.1.360.447
1p4aPCPPur operon repressor/0.447
1pn9GTXGlutathione S-transferase 1, isoform D2.5.1.180.447
1pqc444Oxysterols receptor LXR-beta/0.447
1pwyAC2Purine nucleoside phosphorylase2.4.2.10.447
1ra8FOLDihydrofolate reductase1.5.1.30.447
1txtCAAHMG-CoA synthase/0.447
1yqsBSAD-alanyl-D-alanine carboxypeptidase3.4.16.40.447
2fr1NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.447
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.447
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.447
2vyqFADFerredoxin--NADP reductase1.18.1.20.447
2ztmNADD(-)-3-hydroxybutyrate dehydrogenase/0.447
3a3gDLZLumazine protein/0.447
3cgtBCDCyclomaltodextrin glucanotransferase2.4.1.190.447
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.447
3qvrFADGlucose oxidase1.1.3.40.447
3wrlCAMCamphor 5-monooxygenase1.14.15.10.447
4a81DXCMajor pollen allergen Bet v 1-A/0.447
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4bfzZVZPantothenate kinase2.7.1.330.447
4bqh9VUUDP-N-acetylglucosamine pyrophosphorylase, putative/0.447
4cf6CBDNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
4dh60KNBeta-secretase 13.4.23.460.447
4du82P0Mevalonate diphosphate decarboxylase/0.447
4f5yC2EStimulator of interferon genes protein/0.447
4g3jVNTLanosterol 14-alpha-demethylase/0.447
4o63NADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.447
4qtnNNRNicotinamide riboside transporter PnuC/0.447
4rcvNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.447
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA23.6.30.447
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA1/0.447
5jsfNAD17-beta-hydroxysteroid dehydrogenase 141.1.10.447
1lv89PPPurine nucleoside phosphorylase2.4.2.10.446
1ozpACOMycothiol acetyltransferase2.3.1.1890.446
1u71MXADihydrofolate reductase1.5.1.30.446
1v453DGPurine nucleoside phosphorylase2.4.2.10.446
1vyrFMNPentaerythritol tetranitrate reductase/0.446
2e7rSAHDiphthine synthase/0.446
2eh4SAHDiphthine synthase/0.446
2ekaSAHDiphthine synthase/0.446
2huqSAHDiphthine synthase/0.446
2ntrL00Beta-secretase 13.4.23.460.446
2pkmADNAdenosine kinase2.7.1.200.446
2r8vACOAmino-acid acetyltransferase/0.446
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
2vkeTACTetracycline repressor protein class D/0.446
2wf0ZY0Beta-secretase 13.4.23.460.446
2z3lPHE_ARG_TYR_LEU_GLYLeucyl/phenylalanyl-tRNA--protein transferase2.3.2.60.446
2z4sADPChromosomal replication initiator protein DnaA/0.446
3arnMSJDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial3.6.1.230.446
3flzFLZMitogen-activated protein kinase 14/0.446
3g70A5TRenin3.4.23.150.446
3n4kSAHtRNA (cytidine(34)-2'-O)-methyltransferase/0.446
3p74FMNPentaerythritol tetranitrate reductase/0.446
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.446
4i6h1C8Serine/threonine-protein kinase PLK22.7.11.210.446
4iqqD16Thymidylate synthase/0.446
5a9sNAPPutative dehydrogenase/0.446
1aj8COACitrate synthase/0.445
1bifAGS6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 42.7.1.1050.445
1cbqRE9Cellular retinoic acid-binding protein 2/0.445
1fwmCB3Thymidylate synthase/0.445
1ig0VIBThiamine pyrophosphokinase2.7.6.20.445
1omoNADAlanine dehydrogenase/0.445
1t2cNAIL-lactate dehydrogenase1.1.1.270.445
1t86CAMCamphor 5-monooxygenase1.14.15.10.445
1tehNADAlcohol dehydrogenase class-31.1.1.10.445
1xrpPRO_LEU_GLY_GLYProline iminopeptidase3.4.11.50.445
2b3vACODiamine acetyltransferase 1/0.445
2dwbANPAurora kinase A2.7.11.10.445
2ek4SAHDiphthine synthase/0.445
2fznFADBifunctional protein PutA1.5.5.20.445
2g1r3IGRenin3.4.23.150.445
2okeDUPDUTP pyrophosphatase/0.445
2ovmAS0Progesterone receptor/0.445
2uxhQUEHTH-type transcriptional regulator TtgR/0.445
2x86ADPADP-L-glycero-D-manno-heptose-6-epimerase/0.445
2xtnGTPGTPase IMAP family member 2/0.445
3b04OOPIsopentenyl-diphosphate delta-isomerase/0.445
3cz7ACOHistone acetyltransferase RTT1092.3.1.480.445
3d90NOGProgesterone receptor/0.445
3eldSFGMethyltransferase/0.445
3ih0ANPUncharacterized sugar kinase PH14592.7.10.445
3junAJDPhenazine biosynthesis protein A/B/0.445
3nxvD2FDihydrofolate reductase1.5.1.30.445
3pdqKC6Lysine-specific demethylase 4A1.14.110.445
3vkjFNRIsopentenyl-diphosphate delta-isomerase/0.445
4a6nFADTetX family tetracycline inactivation enzyme/0.445
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.445
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
4emdC5P4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.445
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.445
4kw51W6Decaprenylphosphoryl-beta-D-ribose oxidase/0.445
4o8aFADBifunctional protein PutA1.2.1.880.445
4qxr1YEStimulator of interferon genes protein/0.445
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.445
5kbwRBFRiboflavin transporter RibU/0.445
1a4iNDPC-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.444
1hb3SCVIsopenicillin N synthase1.21.3.10.444
1jlrGTPUracil phosphoribosyltransferase/0.444
1m8kNADNicotinamide-nucleotide adenylyltransferase2.7.7.10.444
1n2jPAFPantothenate synthetase6.3.2.10.444
1o76CAMCamphor 5-monooxygenase1.14.15.10.444
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.444
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1touB1VFatty acid-binding protein, adipocyte/0.444
1yrcCAMCamphor 5-monooxygenase1.14.15.10.444
1zrqFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.444
2fzmFADBifunctional protein PutA1.5.5.20.444
2g21L1BRenin3.4.23.150.444
2he5NDPAldo-keto reductase family 1 member C211.1.10.444
2j62GSZO-GlcNAcase NagJ/0.444
2r6gATPMaltose/maltodextrin import ATP-binding protein MalK/0.444
2uxpCLMHTH-type transcriptional regulator TtgR/0.444
2wo7ASVIsopenicillin N synthase1.21.3.10.444
2xviFADPutative flavin-containing monooxygenase/0.444
2ylrNAPPhenylacetone monooxygenase1.14.13.920.444
3bva2NCGag-Pol polyprotein3.4.23.160.444
3ce0P34Poly [ADP-ribose] polymerase 32.4.2.300.444
3ctyFADProbable thioredoxin reductase/0.444
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3ihzFK5Peptidylprolyl isomerase/0.444
3k8q22APurine nucleoside phosphorylase2.4.2.10.444
3lthUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.444
3n39FMNProtein NrdI/0.444
3q0gBCOProbable enoyl-CoA hydratase echA84.2.1.170.444
3tn8F18Cyclin-dependent kinase 92.7.11.220.444
3uhl2NCGag-Pol polyprotein3.4.23.160.444
3veu0GOBeta-secretase 13.4.23.460.444
3vy5FMNFMN-binding protein/0.444
4cdmFO1Deoxyribodipyrimidine photolyase/0.444
4dpuAGSMevalonate diphosphate decarboxylase/0.444
4ead0NPThymidine phosphorylase2.4.2.40.444
4eox0S5Peptide deformylase/0.444
4hmxFMNPyridoxamine 5'-phosphate oxidase/0.444
4ktkKTKCytochrome P450/0.444
4panGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.444
4qedNAPElxO/0.444
4qxq1YEStimulator of interferon genes protein/0.444
4rp8ASCAscorbate-specific PTS system EIIC component/0.444
4x7uZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.444
1b5dDCMDeoxycytidylate 5-hydroxymethyltransferase2.1.2.80.443
1fdoMGDFormate dehydrogenase H1.1.99.330.443
1g28FMNPHY3/0.443
1iayAVG1-aminocyclopropane-1-carboxylate synthase 24.4.1.140.443
1p0pBCHCholinesterase3.1.1.80.443
1p44NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
1qoqIGPTryptophan synthase alpha chain/0.443
1t6yADPRiboflavin biosynthesis protein/0.443
1yw8A75Methionine aminopeptidase 2/0.443
2b58COADiamine acetyltransferase 1/0.443
2cjfRP43-dehydroquinate dehydratase4.2.1.100.443
2e4nSAHDiphthine synthase/0.443
2freFMNNAD(P)H-flavin oxidoreductase/0.443
2fxeDR7Gag-Pol polyprotein3.4.23.160.443
2iviACWIsopenicillin N synthase1.21.3.10.443
2kmnBB2Peptide deformylase3.5.1.880.443
2p5cSAHDiphthine synthase/0.443
2zs9ADPPantothenate kinase2.7.1.330.443
3ai3NDPNADPH-sorbose reductase/0.443
3b2sB2STrichothecene 3-O-acetyltransferase/0.443
3e5hGNPRas-related protein Rab-28/0.443
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
3iqiASN_GLU_ASN_ILECysteine synthase2.5.1.470.443
3isjA8DPantothenate synthetase6.3.2.10.443
3pce3HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.443
3pce3HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.443
3u9eCOALmo1369 protein/0.443
3u9y09LTankyrase-22.4.2.300.443
3vsxR32Renin3.4.23.150.443
4b65FADL-ornithine N(5)-monooxygenase/0.443
4bfd8T3Beta-secretase 13.4.23.460.443
4eb4UMPThymidylate synthase2.1.1.450.443
4eh70OOMitogen-activated protein kinase 14/0.443
4h6pFMNChromate reductase/0.443
4i8zG08Gag-Pol polyprotein3.4.23.160.443
4js1CTNBeta-galactoside alpha-2,6-sialyltransferase 12.4.99.10.443
4qzuRTLRetinol-binding protein 2/0.443
4rvdSAMD-mycarose 3-C-methyltransferase/0.443
5dv2C5PCCR4-NOT transcription complex subunit 6-like3.1.13.40.443
5kgjACOPredicted acetyltransferase/0.443
6cp4CAMCamphor 5-monooxygenase1.14.15.10.443
5k2dZMAAdenosine receptor A2a/0.443
1bim0QBRenin3.4.23.150.442
1cneFADNitrate reductase [NADH]1.7.1.10.442
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.442
1f0yNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.442
1h51FMNPentaerythritol tetranitrate reductase/0.442
1hk2T44Serum albumin/0.442
1i0sFMNFerric-chelate reductase (NAD(P)H)/0.442
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.442
1nooCAHCamphor 5-monooxygenase1.14.15.10.442
1og4NAIT-cell ecto-ADP-ribosyltransferase 2/0.442
1owe675Urokinase-type plasminogen activator3.4.21.730.442
1pq944BOxysterols receptor LXR-beta/0.442
1pt8ACOFormyl-CoA:oxalate CoA-transferase/0.442
1ptjNAPNAD(P) transhydrogenase subunit beta1.6.1.20.442
1rctNOSPurine nucleoside phosphorylase2.4.2.10.442
1t8xPEP2-dehydro-3-deoxyphosphooctonate aldolase2.5.1.550.442
1tqf32PBeta-secretase 13.4.23.460.442
1v2hGUNPurine nucleoside phosphorylase2.4.2.10.442
1yw7A41Methionine aminopeptidase 2/0.442
1zgi382Prothrombin3.4.21.50.442
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
2aqiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.442
2dwpACP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 32.7.1.1050.442
2e0nSAHPrecorrin-2 C20-methyltransferase/0.442
2ejkSAHDiphthine synthase/0.442
2os3BB2Peptide deformylase/0.442
2owkSAHDiphthine synthase/0.442
2v2zCDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.442
2vxoXMPGMP synthase [glutamine-hydrolyzing]6.3.5.20.442
2wi1ZZ2Heat shock protein HSP 90-alpha/0.442
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.442
2yjwYJWHeat shock protein HSP 90-alpha/0.442
2zshGA3Gibberellin receptor GID1A30.442
3bbpGTPRas-related protein Rab-6A/0.442
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3ex8AIFRiboflavin biosynthesis protein RibD1.1.1.1930.442
3fpjSAMUncharacterized protein/0.442
3ft5MO8Heat shock protein HSP 90-alpha/0.442
3h2sNDPPutative NADH-flavin reductase/0.442
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.442
3jv7NADSecondary alcohol dehydrogenase/0.442
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.442
3kr6UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.442
3mdzEZLCarbonic anhydrase 74.2.1.10.442
3ooiSAMHistone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific2.1.1.430.442
3r83Z14Cyclin-dependent kinase 22.7.11.220.442
3rpeFADPutative modulator of drug activity/0.442
3smkCW714-3-3 protein sigma/0.442
3tnlNADShikimate dehydrogenase (NADP(+))/0.442
3toxNAPPutative oxidoreductase/0.442
3vyeVYERenin3.4.23.150.442
3zkyWT4Isopenicillin N synthase1.21.3.10.442
4afhL0BAchbp/0.442
4ai8DZAHypoxia-inducible factor 1-alpha inhibitor1.14.11.300.442
4ddrMMVDihydrofolate reductase1.5.1.30.442
4dpy2P0Mevalonate diphosphate decarboxylase/0.442
4fqsLYAThymidylate synthase ThyA/0.442
4l4aCAMCamphor 5-monooxygenase1.14.15.10.442
4nbh9CATerminal oxygenase component of carbazole/0.442
1i59ANPChemotaxis protein CheA2.7.13.30.441
1nceCB3Thymidylate synthase/0.441
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.441
1q45FMN12-oxophytodienoate reductase 31.3.1.420.441
1udbUFGUDP-glucose 4-epimerase5.1.3.20.441
1wm1PTBProline iminopeptidase3.4.11.50.441
1wngSAHDiphthine synthase/0.441
1xqp8HGN-glycosylase/DNA lyase/0.441
2a1oCAMCamphor 5-monooxygenase1.14.15.10.441
2dhfDZFDihydrofolate reductase1.5.1.30.441
2e83FMNFMN-binding protein/0.441
2h94FADLysine-specific histone demethylase 1A10.441
2hkoFADLysine-specific histone demethylase 1A10.441
2j7pGNPSignal recognition particle protein/0.441
2j7pGNPSignal recognition particle receptor FtsY/0.441
2oc9IMHPurine nucleoside phosphorylase2.4.2.10.441
2ohvNHLGlutamate racemase/0.441
2p6dSAHDiphthine synthase/0.441
2pfgDDDCarbonyl reductase [NADPH] 11.1.1.1840.441
2v9xDUTdCTP deaminase/0.441
2xvhFADPutative flavin-containing monooxygenase/0.441
3b9xNOSPyrimidine-specific ribonucleoside hydrolase RihB3.2.2.80.441
3fznD7KBenzoylformate decarboxylase4.1.1.70.441
3gi4K60Gag-Pol polyprotein/0.441
3h2cB58Dihydropteroate synthase/0.441
3kigDA4Carbonic anhydrase 24.2.1.10.441
3o5rFK5Peptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.441
3qgf46FGenome polyprotein2.7.7.480.441
3tpr5HABeta-secretase 13.4.23.460.441
3u7lUDBPeptide deformylase/0.441
3v0p4GWHisto-blood group ABO system transferase/0.441
3wrhCAMCamphor 5-monooxygenase1.14.15.10.441
3zbsOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.441
4c02TAKActivin receptor type-12.7.11.300.441
4d0l093Phosphatidylinositol 4-kinase beta2.7.1.670.441
4jwfSAHtRNA (guanine(9)-N1)-methyltransferase/0.441
4kgkGTPUncharacterized protein/0.441
4krs1SXTankyrase-12.4.2.300.441
4nm9FADBifunctional protein PutA/0.441
4py6R78Bromodomain protein, putative/0.441
4yp7NAPNicotinamide-nucleotide adenylyltransferase2.7.7.10.441
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.441
5cyoGDPSeptin-9/0.441
5fsi8DG7,8-dihydro-8-oxoguanine triphosphatase3.6.1.550.441
1a9sNOSPurine nucleoside phosphorylase2.4.2.10.440
1bk0ACVIsopenicillin N synthase1.21.3.10.440
1byqADPHeat shock protein HSP 90-alpha/0.440
1krv147Galactoside O-acetyltransferase2.3.1.180.440
1lruBB2Peptide deformylase3.5.1.880.440
1rb3MTXDihydrofolate reductase1.5.1.30.440
1sbgIM1Gag-Pol polyprotein/0.440
1tilATPAnti-sigma F factor/0.440
1zhaPEP2-dehydro-3-deoxyphosphooctonate aldolase2.5.1.550.440
2a2xNA9Prothrombin3.4.21.50.440
2hxzH7JCathepsin S3.4.22.270.440
2ien017Gag-Pol polyprotein3.4.23.160.440
2iw5FADLysine-specific histone demethylase 1A10.440
2jji0QSEndothiapepsin3.4.23.220.440
2y5kYCUFructose-1,6-bisphosphatase 13.1.3.110.440
3e2sFADBifunctional protein PutA1.5.5.20.440
3hyz42CHeat shock protein HSP 90-alpha/0.440
3iahNAPPutative oxoacyl-(Acyl carrier protein) reductase/0.440
3nxoD2BDihydrofolate reductase1.5.1.30.440
3p2eSAH16S rRNA (adenine(1408)-N(1))-methyltransferase2.1.1.1800.440
3qykIE2Carbonic anhydrase 24.2.1.10.440
3r7wGNPGTP-binding protein GTR2/0.440
4bqzGNPEctonucleoside triphosphate diphosphohydrolase 2/0.440
4c72TLG3-oxoacyl-ACP synthase/0.440
4c9oCAMCytochrome P450/0.440
4ew2DXYTrifunctional purine biosynthetic protein adenosine-32.1.2.20.440
4g9lNGHStromelysin-13.4.24.170.440
4jnkNAIL-lactate dehydrogenase A chain1.1.1.270.440
4wsoNADProbable nicotinate-nucleotide adenylyltransferase/0.440
4xboSAHtRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ2.1.1.2000.440
5bt9NAP3-oxoacyl-(Acyl-carrier-protein) reductase/0.440
5f2kSAHUncharacterized protein/0.440