sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1sqq | OST | Cytochrome b |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1sqq | OST | Cytochrome b | / | 1.000 | |
| 1sqp | MYX | Cytochrome b | / | 0.623 | |
| 1sqb | AZO | Cytochrome b | / | 0.621 | |
| 3tgu | WF3 | Cytochrome b | / | 0.583 | |
| 3l70 | JZV | Cytochrome b | / | 0.556 | |
| 3l71 | AZO | Cytochrome b | / | 0.538 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.523 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.515 | |
| 5bt4 | 2LO | Bromodomain-containing protein 4 | / | 0.514 | |
| 1buc | FAD | Acyl-CoA dehydrogenase, short-chain specific | 1.3.8.1 | 0.511 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.511 | |
| 3q0g | BCO | Probable enoyl-CoA hydratase echA8 | 4.2.1.17 | 0.511 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.509 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.507 | |
| 4iah | 1DX | Alr2278 protein | / | 0.507 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.507 | |
| 1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.506 | |
| 4tzt | 468 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.506 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.505 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.505 | |
| 4qpz | TPP | Benzaldehyde lyase | / | 0.504 | |
| 5dq8 | FLF | Transcriptional enhancer factor TEF-4 | / | 0.504 | |
| 1ia1 | TQ3 | Dihydrofolate reductase | 1.5.1.3 | 0.503 | |
| 3gie | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.503 | |
| 4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.503 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.502 | |
| 1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.501 | |
| 1fby | REA | Retinoic acid receptor RXR-alpha | / | 0.501 | |
| 2p15 | EZT | Estrogen receptor | / | 0.501 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.501 | |
| 3eon | 341 | Glutaryl-CoA dehydrogenase | / | 0.501 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.501 | |
| 1l2j | ETC | Estrogen receptor beta | / | 0.499 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.499 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.499 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.498 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.498 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.498 | |
| 4bfr | J82 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 2.7.1.153 | 0.498 | |
| 3fu8 | 3DM | Laccase-1 | 1.10.3.2 | 0.497 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.497 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.497 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.496 | |
| 2vcg | S17 | Histone deacetylase-like amidohydrolase | 3.5.1 | 0.496 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.496 | |
| 1fd0 | 254 | Retinoic acid receptor gamma | / | 0.495 | |
| 1fcx | 184 | Retinoic acid receptor gamma | / | 0.494 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.494 | |
| 3bjh | NBB | Odorant binding protein ASP1 | / | 0.494 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.494 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.493 | |
| 3qpp | PFW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.493 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.493 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.492 | |
| 1uhl | MEI | Retinoic acid receptor RXR-beta | / | 0.492 | |
| 2w3v | TOP | Dihydrofolate reductase | / | 0.492 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.492 | |
| 4h98 | 14Q | Uncharacterized protein | / | 0.492 | |
| 4j36 | 1HR | Kynurenine 3-monooxygenase | / | 0.492 | |
| 1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.491 | |
| 3cyz | 9OD | Pheromone-binding protein ASP1 | / | 0.491 | |
| 3cz0 | 9OD | Pheromone-binding protein ASP1 | / | 0.491 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.491 | |
| 5ab7 | MLC | Nonspecific lipid-transfer protein, putative | / | 0.491 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.491 | |
| 1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.490 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.490 | |
| 3qly | 55V | Uncharacterized protein | / | 0.490 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.490 | |
| 4dsb | A8S | Abscisic acid receptor PYL3 | / | 0.490 | |
| 2acw | UPG | Glycosyltransferase | / | 0.489 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.489 | |
| 3oap | REA | Retinoic acid receptor RXR-alpha | / | 0.489 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 1ly3 | COG | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.488 | |
| 3r3b | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.488 | |
| 3td8 | D2R | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.488 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.488 | |
| 1uml | FR4 | Adenosine deaminase | 3.5.4.4 | 0.487 | |
| 1xuo | LA1 | Integrin alpha-L | / | 0.487 | |
| 3fy9 | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.487 | |
| 4iae | 1DX | Alr2278 protein | / | 0.487 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.487 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.486 | |
| 1kb9 | SMA | Cytochrome b | / | 0.486 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.486 | |
| 3sl6 | JN8 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.486 | |
| 1fcy | 564 | Retinoic acid receptor gamma | / | 0.485 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.485 | |
| 2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.485 | |
| 2blc | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.485 | |
| 3htj | ET | EbrA repressor | / | 0.485 | |
| 3srw | Q27 | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
| 4gue | QCT | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.485 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.485 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.485 | |
| 1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.484 | |
| 2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.484 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.484 | |
| 3zec | ANP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.484 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.484 | |
| 4elb | 34R | Dihydrofolate reductase | / | 0.484 | |
| 4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.484 | |
| 1dg5 | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.483 | |
| 1e7a | PFL | Serum albumin | / | 0.483 | |
| 1ju6 | LYA | Thymidylate synthase | 2.1.1.45 | 0.483 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.483 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.483 | |
| 3new | 3NE | Mitogen-activated protein kinase 14 | / | 0.483 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.483 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.483 | |
| 4myq | 19T | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.483 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.482 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.482 | |
| 2g2h | P16 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.482 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.482 | |
| 3n8z | FLP | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.482 | |
| 3p9t | TCL | Repressor | / | 0.482 | |
| 3uwl | FOZ | Thymidylate synthase | / | 0.482 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.482 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.482 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.482 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.482 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.482 | |
| 5ab6 | CAA | Nonspecific lipid-transfer protein, putative | / | 0.482 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.481 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.481 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.481 | |
| 1xdk | REA | Retinoic acid receptor beta | / | 0.481 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.481 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.481 | |
| 2agv | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.481 | |
| 2h42 | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.481 | |
| 2x20 | PID | Peridinin-chlorophyll a-binding protein 1, chloroplastic | / | 0.481 | |
| 4a0s | CO8 | Octenoyl-CoA reductase/carboxylase | / | 0.481 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.481 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.481 | |
| 1jom | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 1m78 | CLZ | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.480 | |
| 2b01 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.480 | |
| 3dho | B2M | Streptogramin A acetyltransferase | 2.3.1 | 0.480 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.480 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.480 | |
| 3tky | N7I | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.480 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.480 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.480 | |
| 4equ | G6I | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.480 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.480 | |
| 4nx6 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.480 | |
| 1ia2 | TQ4 | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.479 | |
| 2lbd | REA | Retinoic acid receptor gamma | / | 0.479 | |
| 3oez | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.479 | |
| 3s41 | S41 | Glucokinase | 2.7.1.2 | 0.479 | |
| 3sl8 | JN7 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.479 | |
| 3v1m | HPK | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | 3.7.1.8 | 0.479 | |
| 4cav | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.479 | |
| 4ea1 | 3RX | Dehydrosqualene synthase | / | 0.479 | |
| 1chw | HXC | Chalcone synthase 2 | 2.3.1.74 | 0.478 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.478 | |
| 1xdu | SFG | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.478 | |
| 3eek | 53S | Uncharacterized protein | / | 0.478 | |
| 3eel | 53T | Uncharacterized protein | / | 0.478 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.478 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.478 | |
| 3pg3 | DG7 | Mitogen-activated protein kinase 14 | / | 0.478 | |
| 3t8x | T8X | T-cell surface glycoprotein CD1b | / | 0.478 | |
| 3t9i | 3T9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.478 | |
| 4dm6 | TTB | Retinoic acid receptor beta | / | 0.478 | |
| 4zhi | ADP | Kinesin-like protein KIF11 | / | 0.478 | |
| 1m7a | MQU | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 1olm | VTQ | SEC14-like protein 2 | / | 0.477 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.477 | |
| 2i9p | NAD | 3-hydroxyisobutyrate dehydrogenase, mitochondrial | 1.1.1.31 | 0.477 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.477 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.477 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.477 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.477 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.477 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.477 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.477 | |
| 3wiy | LC6 | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.477 | |
| 4fny | I3K | ALK tyrosine kinase receptor | 2.7.10.1 | 0.477 | |
| 4jaq | COA | Alpha-pyrone synthesis polyketide synthase-like Pks11 | 2.3.1 | 0.477 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.477 | |
| 5c8d | 5AD | Probable transcriptional regulator | / | 0.477 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.476 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.476 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.476 | |
| 1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.476 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.476 | |
| 2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.476 | |
| 2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.476 | |
| 2x21 | PID | Peridinin-chlorophyll a-binding protein 1, chloroplastic | / | 0.476 | |
| 2z7g | EH9 | Adenosine deaminase | 3.5.4.4 | 0.476 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.476 | |
| 3c96 | FAD | Flavin-containing monooxygenase | / | 0.476 | |
| 3cd2 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.476 | |
| 4hut | ATP | Cob(I)yrinic acid a,c-diamide adenosyltransferase | 2.5.1.17 | 0.476 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.476 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.476 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.476 | |
| 1lwl | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.475 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.475 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.475 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.475 | |
| 2b35 | TCL | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.475 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.475 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.475 | |
| 3ar7 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.475 | |
| 3dol | GWI | Pol protein | / | 0.475 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.475 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.475 | |
| 4ixc | 1JD | Glucokinase | 2.7.1.2 | 0.475 | |
| 1juj | LYA | Thymidylate synthase | 2.1.1.45 | 0.474 | |
| 1l0l | FMX | Cytochrome b | / | 0.474 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.474 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.474 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.474 | |
| 2ilt | NN1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.474 | |
| 2mm3 | CHO | Gastrotropin | / | 0.474 | |
| 2rht | C1E | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | 3.7.1.8 | 0.474 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.474 | |
| 3d0b | SNX | Heat shock protein HSP 90-alpha | / | 0.474 | |
| 3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.474 | |
| 3m7r | VDX | Vitamin D3 receptor | / | 0.474 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.474 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.474 | |
| 3up3 | XCA | aceDAF-12 | / | 0.474 | |
| 4k4j | 1O8 | Retinoic acid receptor RXR-alpha | / | 0.474 | |
| 4zas | TYD | CalS13 | / | 0.474 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.473 | |
| 1exa | 394 | Retinoic acid receptor gamma | / | 0.473 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.473 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.473 | |
| 1u0w | STL | Chalcone synthase 2 | 2.3.1.74 | 0.473 | |
| 1v7a | FRC | Adenosine deaminase | 3.5.4.4 | 0.473 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.473 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.473 | |
| 2y0j | AXC | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.473 | |
| 3d75 | NBB | Pheromone-binding protein ASP1 | / | 0.473 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.473 | |
| 3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.473 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.473 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.473 | |
| 4fox | D16 | Thymidylate synthase ThyA | / | 0.473 | |
| 4iwv | 1J9 | Glucokinase | 2.7.1.2 | 0.473 | |
| 4paa | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.473 | |
| 1ezf | IN0 | Squalene synthase | 2.5.1.21 | 0.472 | |
| 1fro | GSB | Lactoylglutathione lyase | 4.4.1.5 | 0.472 | |
| 1n71 | COA | Aac(6')-Ii protein | / | 0.472 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.472 | |
| 2d06 | EST | Sulfotransferase 1A1 | 2.8.2.1 | 0.472 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.472 | |
| 2r6j | NDP | Eugenol synthase 1 | 1.1.1.318 | 0.472 | |
| 3b9l | AZZ | Serum albumin | / | 0.472 | |
| 3djl | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.472 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.472 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.472 | |
| 3ldf | SAH | Uncharacterized protein | / | 0.472 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.472 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.472 | |
| 4fgh | 0U6 | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.472 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.472 | |
| 1err | RAL | Estrogen receptor | / | 0.471 | |
| 1mzn | BM6 | Retinoic acid receptor RXR-alpha | / | 0.471 | |
| 2b00 | GCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.471 | |
| 2fpc | SCG | Strictosidine synthase | 4.3.3.2 | 0.471 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.471 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.471 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.471 | |
| 3g4l | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.471 | |
| 3h1j | SMA | Cytochrome b | / | 0.471 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.471 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.471 | |
| 3qlr | QLR | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 3zrr | PXG | Serine-pyruvate aminotransferase (AgxT) | / | 0.471 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.471 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.471 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.471 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.471 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.470 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.470 | |
| 1xiu | REA | Retinoic acid receptor RXR | / | 0.470 | |
| 1xqc | AEJ | Estrogen receptor | / | 0.470 | |
| 2gh6 | CF3 | Histone deacetylase-like amidohydrolase | 3.5.1 | 0.470 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.470 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.470 | |
| 2w9g | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.470 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.470 | |
| 3hx3 | RET | Retinaldehyde-binding protein 1 | / | 0.470 | |
| 3irx | UDR | Gag-Pol polyprotein | 2.7.7.49 | 0.470 | |
| 3nta | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.470 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.470 | |
| 5i2h | AGI | O-methyltransferase family 2 | / | 0.470 | |
| 1a4i | NDP | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.469 | |
| 1kij | NOV | DNA gyrase subunit B | / | 0.469 | |
| 1osv | CHC | Bile acid receptor | / | 0.469 | |
| 2qd5 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.469 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.469 | |
| 2xvw | 9NR | Serum albumin | / | 0.469 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.469 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.469 | |
| 3cse | N22 | Uncharacterized protein | / | 0.469 | |
| 3fu9 | KIB | Laccase-1 | 1.10.3.2 | 0.469 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.469 | |
| 3ntd | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.469 | |
| 4jv8 | 1M1 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.469 | |
| 4ea3 | 0NN | Nociceptin receptor | / | 0.469 | |
| 1fp1 | HCC | Isoliquiritigenin 2'-O-methyltransferase | / | 0.468 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 1mc5 | AHE | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.468 | |
| 1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.468 | |
| 1r6g | 442 | Thyroid hormone receptor beta | / | 0.468 | |
| 1rdt | L79 | Retinoic acid receptor RXR-alpha | / | 0.468 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.468 | |
| 2ban | 357 | Gag-Pol polyprotein | 2.7.7.49 | 0.468 | |
| 2bxq | IMN | Serum albumin | / | 0.468 | |
| 2fhj | MFN | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.468 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.468 | |
| 3anl | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.468 | |
| 3dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.468 | |
| 3jwc | EKB | Dihydrofolate reductase | / | 0.468 | |
| 3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.468 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.468 | |
| 4l9q | 9TP | Serum albumin | / | 0.468 | |
| 1ezv | SMA | Cytochrome b | / | 0.467 | |
| 1fm6 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.467 | |
| 1s3w | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 2e9d | B76 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.467 | |
| 2puj | HPZ | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | 3.7.1.8 | 0.467 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.467 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.467 | |
| 3qls | 55V | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.467 | |
| 4do3 | 0LA | Fatty-acid amide hydrolase 1 | 3.5.1.99 | 0.467 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.467 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.467 | |
| 4k6i | 9RA | Retinoic acid receptor RXR-alpha | / | 0.467 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 4pkl | 1GH | Uncharacterized protein | / | 0.467 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.467 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.467 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.467 | |
| 1bzf | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.466 | |
| 1dlr | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.466 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.466 | |
| 1lri | CLR | Beta-elicitin cryptogein | / | 0.466 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.466 | |
| 2ay3 | MPP | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.466 | |
| 2e98 | B29 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.466 | |
| 2jj1 | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.466 | |
| 2jj1 | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.466 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.466 | |
| 2qjy | SMA | Cytochrome b | / | 0.466 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.466 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.466 | |
| 3cv9 | VDX | Vitamin D3 dihydroxylase | / | 0.466 | |
| 3dga | RJ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.466 | |
| 3ds6 | A17 | Mitogen-activated protein kinase 14 | / | 0.466 | |
| 3hbb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.466 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.466 | |
| 3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.466 | |
| 3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 3owu | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.466 | |
| 4b5o | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.466 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.466 | |
| 4l02 | 1V2 | Sphingosine kinase 1 | 2.7.1.91 | 0.466 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.466 | |
| 4wev | SUZ | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.466 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.466 | |
| 3rfm | CFF | Adenosine receptor A2a | / | 0.466 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.465 | |
| 1jut | LYD | Thymidylate synthase | / | 0.465 | |
| 1jx0 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.465 | |
| 1khr | VIR | Streptogramin A acetyltransferase | 2.3.1 | 0.465 | |
| 1mab | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.465 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.465 | |
| 2aib | ERG | Beta-elicitin cinnamomin | / | 0.465 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.465 | |
| 2igx | A1T | Plasmepsin 2 | / | 0.465 | |
| 2iwu | NP5 | ATP-dependent molecular chaperone HSP82 | / | 0.465 | |
| 2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 2x1z | PID | Peridinin-chlorophyll a-binding protein 1, chloroplastic | / | 0.465 | |
| 2xvv | 9DN | Serum albumin | / | 0.465 | |
| 3f0r | TSN | Histone deacetylase 8 | 3.5.1.98 | 0.465 | |
| 3fyv | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.465 | |
| 3qlw | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.465 | |
| 3zln | H0Y | Bcl-2-like protein 1 | / | 0.465 | |
| 4ddr | MMV | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.465 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.465 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.465 | |
| 4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 4l8u | 9AZ | Serum albumin | / | 0.465 | |
| 4o76 | 1M3 | Bromodomain-containing protein 4 | / | 0.465 | |
| 1q4x | G24 | Thyroid hormone receptor beta | / | 0.464 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.464 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.464 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.464 | |
| 2wpw | ACO | Orf14 | / | 0.464 | |
| 3ar5 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.464 | |
| 3bej | MUF | Bile acid receptor | / | 0.464 | |
| 3eej | 53R | Uncharacterized protein | / | 0.464 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.464 | |
| 3iqz | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.464 | |
| 3o57 | ZG2 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.464 | |
| 3qlx | QLR | Uncharacterized protein | / | 0.464 | |
| 3qlz | QLZ | Uncharacterized protein | / | 0.464 | |
| 4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.464 | |
| 4bfp | SWY | Tankyrase-2 | 2.4.2.30 | 0.464 | |
| 4ckr | DI1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.464 | |
| 4eil | UMP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.464 | |
| 4h6z | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.464 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.464 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.464 | |
| 4mle | VO1 | Glucokinase | 2.7.1.2 | 0.464 | |
| 4qii | 2NE | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.464 | |
| 4u95 | MIY | Multidrug efflux pump subunit AcrB | / | 0.464 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.463 | |
| 1m52 | P17 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.463 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.463 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.463 | |
| 2c9e | PID | Peridinin-chlorophyll a protein, high-salt form | / | 0.463 | |
| 2fmn | 4HF | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.463 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.463 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.463 | |
| 2imk | GTX | AGAP009194-PA | / | 0.463 | |
| 2jfz | 003 | Glutamate racemase | / | 0.463 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.463 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.463 | |
| 3d77 | NBB | Pheromone-binding protein ASP1 | / | 0.463 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.463 | |
| 3nwx | KVS | Gag-Pol polyprotein | 3.4.23.16 | 0.463 | |
| 3pm9 | FAD | Putative oxidoreductase | / | 0.463 | |
| 3tqb | FOL | Dihydrofolate reductase | / | 0.463 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.463 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.463 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.463 | |
| 4g8b | HL6 | Alpha/beta hydrolase fold protein | / | 0.463 | |
| 4ie0 | PD2 | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.463 | |
| 4mt9 | 2D6 | Tankyrase-1 | 2.4.2.30 | 0.463 | |
| 4rgs | V55 | Repressor protein | / | 0.463 | |
| 4ug2 | NGI | Adenosine receptor A2a | / | 0.463 | |
| 1bif | AGS | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | 2.7.1.105 | 0.462 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.462 | |
| 1gt5 | BZQ | Odorant-binding protein | / | 0.462 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.462 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.462 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.462 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.462 | |
| 2blb | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.462 | |
| 2ewa | SB2 | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.462 | |
| 2za0 | MGI | Lactoylglutathione lyase | 4.4.1.5 | 0.462 | |
| 3d5f | L41 | Peroxisome proliferator-activated receptor delta | / | 0.462 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.462 | |
| 3njo | P2M | Abscisic acid receptor PYR1 | / | 0.462 | |
| 3upy | FOM | Oxidoreductase, putative | / | 0.462 | |
| 3uvv | REA | Retinoic acid receptor RXR-alpha | / | 0.462 | |
| 3vjc | ZGA | Squalene synthase | 2.5.1.21 | 0.462 | |
| 3wd7 | COA | Acridone synthase | / | 0.462 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.462 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.462 | |
| 4e6a | 0O9 | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 4elg | 52J | Dihydrofolate reductase | / | 0.462 | |
| 4l4x | NDP | AmphI | / | 0.462 | |
| 5d7p | OCZ | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.462 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.461 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1owp | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.461 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.461 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.461 | |
| 2bxm | IMN | Serum albumin | / | 0.461 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.461 | |
| 3d74 | NBB | Pheromone-binding protein ASP1 | / | 0.461 | |
| 3d78 | NBB | Pheromone-binding protein ASP1 | / | 0.461 | |
| 3ict | ADP | Coenzyme A disulfide reductase | / | 0.461 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.461 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 3qaq | QAQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.461 | |
| 3tub | FPU | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.461 | |
| 4a99 | MIY | TetX family tetracycline inactivation enzyme | / | 0.461 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.461 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.461 | |
| 4n70 | 2HX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.461 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.461 | |
| 4phu | 2YB | Free fatty acid receptor 1 | / | 0.461 | |
| 1dg7 | WRB | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1k74 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.460 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.460 | |
| 1q4u | 4CA | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.460 | |
| 3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.460 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.460 | |
| 3qlh | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.460 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.460 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.460 | |
| 4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 0.460 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 4nmc | FAD | Bifunctional protein PutA | / | 0.460 | |
| 4nx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 4p6w | MOF | Glucocorticoid receptor | / | 0.460 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.460 | |
| 3pwh | ZMA | Adenosine receptor A2a | / | 0.460 | |
| 1eio | GCH | Gastrotropin | / | 0.459 | |
| 1ep4 | S11 | Gag-Pol polyprotein | 2.7.7.49 | 0.459 | |
| 1hpz | AAP | Gag-Pol polyprotein | 2.7.7.49 | 0.459 | |
| 1r0e | DFN | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.459 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.459 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.459 | |
| 2ay9 | 5PV | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.459 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 2qo4 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.459 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.459 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.459 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.459 | |
| 3hz1 | 42C | Heat shock protein HSP 90-alpha | / | 0.459 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.459 | |
| 3pgh | FLP | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.459 | |
| 3t37 | FAD | Pyridoxine 4-oxidase | / | 0.459 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.459 | |
| 4awo | 99B | Heat shock protein HSP 90-alpha | / | 0.459 | |
| 4eqx | FAD | Coenzyme A disulfide reductase | / | 0.459 | |
| 4f1s | F1S | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.459 | |
| 4g2i | 0VQ | Vitamin D3 receptor | / | 0.459 | |
| 4h38 | 0YX | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.459 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.459 | |
| 4ixd | 1HV | Integrin alpha-L | / | 0.459 | |
| 4ixe | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.459 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.459 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.459 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.459 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.459 | |
| 1av5 | AP2 | Histidine triad nucleotide-binding protein 1 | 3 | 0.458 | |
| 1eii | RTL | Retinol-binding protein 2 | / | 0.458 | |
| 1h9z | RWF | Serum albumin | / | 0.458 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.458 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.458 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.458 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.458 | |
| 1zz1 | SHH | Histone deacetylase-like amidohydrolase | 3.5.1 | 0.458 | |
| 2b0m | 201 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.458 | |
| 2lf1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 3fl8 | RAR | Dihydrofolate reductase | / | 0.458 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.458 | |
| 3oqu | A8S | Abscisic acid receptor PYL9 | / | 0.458 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.458 | |
| 3r35 | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.458 | |
| 3sh2 | 5DR | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 3srq | Q19 | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 4dm8 | REA | Retinoic acid receptor beta | / | 0.458 | |
| 4dph | P65 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.458 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.458 | |
| 4k4e | K4E | Tankyrase-1 | 2.4.2.30 | 0.458 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.458 | |
| 4okx | 198 | Androgen receptor | / | 0.458 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.458 | |
| 1bh5 | GTX | Lactoylglutathione lyase | 4.4.1.5 | 0.457 | |
| 1dib | L34 | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.457 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 1k8z | IAG | Tryptophan synthase alpha chain | / | 0.457 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1nde | MON | Estrogen receptor beta | / | 0.457 | |
| 1ne6 | SP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.457 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.457 | |
| 1s0x | C3S | Nuclear receptor ROR-alpha | / | 0.457 | |
| 1s9d | AFB | Cytohesin-2 | / | 0.457 | |
| 1s9d | AFB | ADP-ribosylation factor 1 | / | 0.457 | |
| 1sqv | UHD | Cytochrome b | / | 0.457 | |
| 2azy | CHD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.457 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.457 | |
| 2hm9 | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 3cx5 | SMA | Cytochrome b | / | 0.457 | |
| 3dr1 | C5D | Vitamin D3 receptor A | / | 0.457 | |
| 3fnh | JPJ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 3ldg | SAH | Uncharacterized protein | / | 0.457 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.457 | |
| 3o4r | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.457 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 3sgx | 0FW | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.457 | |
| 3vo2 | FAD | Ferredoxin--NADP reductase | / | 0.457 | |
| 4bgi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 4elb | 34S | Dihydrofolate reductase | / | 0.457 | |
| 4hee | 14R | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 4jda | A9S | Abscisic acid receptor PYL3 | / | 0.457 | |
| 4jvl | EST | Estrogen sulfotransferase | 2.8.2.4 | 0.457 | |
| 4o7u | THF | Thymidylate synthase | / | 0.457 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.457 | |
| 4trj | 665 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 4u0k | 744 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 4z44 | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.457 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.456 | |
| 1dia | L24 | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.456 | |
| 1f4g | TP4 | Thymidylate synthase | / | 0.456 | |
| 1jtu | LYB | Thymidylate synthase | / | 0.456 | |
| 1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.456 | |
| 1v79 | FR7 | Adenosine deaminase | 3.5.4.4 | 0.456 | |
| 1w83 | L11 | Mitogen-activated protein kinase 14 | / | 0.456 | |
| 2jfg | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.456 | |
| 2jg7 | NAD | Antiquitin | / | 0.456 | |
| 2oiq | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.456 | |
| 2qx7 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.456 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 2vdv | SAM | tRNA (guanine-N(7)-)-methyltransferase | / | 0.456 | |
| 2xk8 | 5R1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.456 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 3a7d | FBN | Catechol O-methyltransferase | 2.1.1.6 | 0.456 | |
| 3bzu | A21 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.456 | |
| 3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.456 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.456 | |
| 3dau | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.456 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.456 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.456 | |
| 3vuf | ADP | Granule-bound starch synthase 1, chloroplastic/amyloplastic | 2.4.1.242 | 0.456 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.456 | |
| 3wix | LC3 | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.456 | |
| 4a2j | AS0 | Progesterone receptor | / | 0.456 | |
| 4ag7 | COA | Glucosamine 6-phosphate N-acetyltransferase | / | 0.456 | |
| 4eh9 | IRG | Mitogen-activated protein kinase 14 | / | 0.456 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.456 | |
| 4iw8 | KN3 | Estrogen receptor | / | 0.456 | |
| 4pds | ANP | Serine/threonine-protein kinase RAD53 | 2.7.12.1 | 0.456 | |
| 5hi6 | MTX | Dihydrofolate reductase | / | 0.456 | |
| 1ci7 | CB3 | Thymidylate synthase | 2.1.1.45 | 0.455 | |
| 1eqg | IBP | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.455 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.455 | |
| 1lgt | BP3 | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.455 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.455 | |
| 1wrl | TFP | Troponin C, slow skeletal and cardiac muscles | / | 0.455 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.455 | |
| 1xls | REA | Retinoic acid receptor RXR-alpha | / | 0.455 | |
| 2cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 2e99 | B08 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.455 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.455 | |
| 2p4i | MR9 | Angiopoietin-1 receptor | 2.7.10.1 | 0.455 | |
| 2psj | CEI | Renilla-luciferin 2-monooxygenase | 1.13.12.5 | 0.455 | |
| 2vss | ACO | Hydroxycinnamoyl-CoA hydratase-lyase | 4.1.2.41 | 0.455 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.455 | |
| 3d80 | Q22 | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3ey4 | 352 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.455 | |
| 3fnf | JPM | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 3frf | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.455 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.455 | |
| 4c3y | FAD | 3-ketosteroid dehydrogenase | / | 0.455 | |
| 4cry | ACO | PanD regulatory factor | / | 0.455 | |
| 4el9 | AFE | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.455 | |
| 4fl0 | PLP | Aminotransferase ALD1, chloroplastic | 2.6.1 | 0.455 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.455 | |
| 4jv6 | 18F | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.455 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.455 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.455 | |
| 4yx6 | FMN | Omega-3 polyunsaturated fatty acid synthase subunit PfaD | / | 0.455 | |
| 4zqc | F6F | Tryptophan synthase alpha chain | / | 0.455 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.454 | |
| 1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.454 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.454 | |
| 1o6r | R19 | Squalene--hopene cyclase | 4.2.1.129 | 0.454 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 2cl5 | BIE | Catechol O-methyltransferase | 2.1.1.6 | 0.454 | |
| 2ops | HBQ | Gag-Pol polyprotein | 2.7.7.49 | 0.454 | |
| 2p1v | 5TN | Retinoic acid receptor RXR-alpha | / | 0.454 | |
| 3a8i | C2F | Aminomethyltransferase | 2.1.2.10 | 0.454 | |
| 3cr7 | PPS | Adenylyl-sulfate kinase | 2.7.1.25 | 0.454 | |
| 3ept | FDA | Putative FAD-monooxygenase | / | 0.454 | |
| 3ghw | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.454 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.454 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 3i1f | GCP | Translation initiation factor 2 subunit gamma | / | 0.454 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.454 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.454 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.454 | |
| 3reo | EUG | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.454 | |
| 3tq9 | MTX | Dihydrofolate reductase | / | 0.454 | |
| 3wsb | RWZ | Farnesyltransferase, putative | / | 0.454 | |
| 4b5n | FMN | NAD(P)H:flavin oxidoreductase Sye4 | / | 0.454 | |
| 4c2j | COA | 3-ketoacyl-CoA thiolase, mitochondrial | 2.3.1.16 | 0.454 | |
| 4elf | 35I | Dihydrofolate reductase | / | 0.454 | |
| 4fgg | 0U5 | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.454 | |
| 4gh3 | 0EV | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.454 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.454 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.454 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.454 | |
| 4xyb | NDP | Formate dehydrogenase | / | 0.454 | |
| 5iw5 | NMN | NADH pyrophosphatase | / | 0.454 | |
| 1jjt | BDS | Beta-lactamase | / | 0.453 | |
| 1m79 | MQ1 | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1nbm | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.453 | |
| 1ozq | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.453 | |
| 1rgs | CMP | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.453 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1th6 | OIN | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.453 | |
| 1tlc | F89 | Thymidylate synthase | / | 0.453 | |
| 1wxy | FRK | Adenosine deaminase | 3.5.4.4 | 0.453 | |
| 1zsn | TN2 | Enoyl-ACP reductase | / | 0.453 | |
| 2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.453 | |
| 2b5j | 3AC | Gag-Pol polyprotein | 2.7.7.49 | 0.453 | |
| 2e9c | B75 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.453 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.453 | |
| 2hzi | JIN | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.453 | |
| 2ji9 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.453 | |
| 2jj2 | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.453 | |
| 2jj2 | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.453 | |
| 2rab | NAD | Glutathione amide reductase | / | 0.453 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.453 | |
| 3i6r | J5Z | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.453 | |
| 3jrx | S1A | Acetyl-CoA carboxylase 2 | / | 0.453 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.453 | |
| 3q5k | D1U | Heat shock protein 83-1 | / | 0.453 | |
| 3qj5 | 022 | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.453 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.453 | |
| 3um8 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.453 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.453 | |
| 3wi2 | P98 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
| 4flh | 14K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 4i42 | 1HA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.453 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.453 | |
| 4klr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.453 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.453 | |
| 4oe4 | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.453 | |
| 5je2 | SAH | Methyl transferase | / | 0.453 | |
| 1fml | RTL | Retinol dehydratase | / | 0.452 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1kyo | SMA | Cytochrome b | / | 0.452 | |
| 1q4g | BFL | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.452 | |
| 1qzz | SAM | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.452 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1s5k | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.452 | |
| 1vru | AAP | Gag-Pol polyprotein | 2.7.7.49 | 0.452 | |
| 2bel | CBO | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.452 | |
| 2ehq | NAP | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.452 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.452 | |
| 2ibz | SMA | Cytochrome b | / | 0.452 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.452 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 2oye | IM8 | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.452 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.452 | |
| 2q5p | 241 | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 2uxu | NAR | HTH-type transcriptional regulator TtgR | / | 0.452 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.452 | |
| 2xk7 | 30E | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.452 | |
| 3aba | FLI | Cytochrome P450 | / | 0.452 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.452 | |
| 3d73 | NBB | Pheromone-binding protein ASP1 | / | 0.452 | |
| 3g1m | RF3 | HTH-type transcriptional regulator EthR | / | 0.452 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.452 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3o73 | O73 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.452 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.452 | |
| 3tfq | 07M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.452 | |
| 3ua5 | 06X | Cytochrome P450 2B6 | 1.14.13 | 0.452 | |
| 3zze | 6XP | Hepatocyte growth factor receptor | 2.7.10.1 | 0.452 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 4ezk | 0SD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.452 | |
| 4g1n | NZT | Pyruvate kinase PKM | 2.7.1.40 | 0.452 | |
| 4m52 | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.452 | |
| 4m8h | R4M | Retinoic acid receptor RXR-alpha | / | 0.452 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 4tzk | 641 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 5c4f | UPG | Histo-blood group ABO system transferase | / | 0.452 | |
| 5jad | FB2 | Platelet-activating factor acetylhydrolase | 3.1.1.47 | 0.452 | |
| 5jqb | IBP | Envelope glycoprotein | / | 0.452 | |
| 5kf2 | COA | Predicted acetyltransferase | / | 0.452 | |
| 1cjc | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.451 | |
| 1dig | L37 | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.451 | |
| 1e1n | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.451 | |
| 1e1q | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.451 | |
| 1f3e | DPZ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.451 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.451 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.451 | |
| 1mvc | BM6 | Retinoic acid receptor RXR-alpha | / | 0.451 | |
| 1ove | 358 | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 1ppj | ANY | Cytochrome b | / | 0.451 | |
| 1pz1 | NAP | General stress protein 69 | / | 0.451 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.451 | |
| 1s6q | TPB | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 1u3s | 797 | Estrogen receptor beta | / | 0.451 | |
| 1w2c | ANP | Inositol-trisphosphate 3-kinase A | 2.7.1.127 | 0.451 | |
| 1yin | CM3 | Estrogen receptor | / | 0.451 | |
| 1zga | HMK | Isoflavone 4'-O-methyltransferase | / | 0.451 | |
| 2a19 | ANP | Interferon-induced, double-stranded RNA-activated protein kinase | 2.7.11.1 | 0.451 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.451 | |
| 2e20 | B4P | Propionate kinase | / | 0.451 | |
| 2fdy | D4G | Cytochrome P450 2A6 | 1.14.13 | 0.451 | |
| 2g0b | NLT | Long-chain N-acyl amino acid synthase | / | 0.451 | |
| 2jbl | SMA | Reaction center protein L chain | / | 0.451 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.451 | |
| 3arv | SAU | Chitinase A | / | 0.451 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3eem | 53V | Uncharacterized protein | / | 0.451 | |
| 3f82 | 353 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.451 | |
| 3gob | HXX | DdmC | / | 0.451 | |
| 3hub | 469 | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.451 | |
| 3hz1 | 37D | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3lak | KR1 | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 3n33 | AES | Beta-peptidyl aminopeptidase BapA | / | 0.451 | |
| 3n8x | NIM | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.451 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.451 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.451 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.451 | |
| 3w0u | HPW | Lactoylglutathione lyase | 4.4.1.5 | 0.451 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.451 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.451 | |
| 4a9i | P9I | Bromodomain-containing protein 2 | / | 0.451 | |
| 4at4 | T6E | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.451 | |
| 4c2w | ANP | Aurora kinase B-A | 2.7.11.1 | 0.451 | |
| 4cax | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.451 | |
| 4ejh | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.451 | |
| 4h6r | FDA | Proline dehydrogenase | / | 0.451 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.451 | |
| 4mm9 | FVX | Na(+):neurotransmitter symporter (Snf family) | / | 0.451 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.451 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.451 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.451 | |
| 1bvr | THT | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 1e26 | GPB | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1efv | FAD | Electron transfer flavoprotein subunit alpha, mitochondrial | / | 0.450 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.450 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.450 | |
| 1odn | APV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1rek | B8L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.450 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 1zhz | ERG | Oxysterol-binding protein homolog 4 | / | 0.450 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.450 | |
| 2b37 | 8PS | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 2cle | F6F | Tryptophan synthase alpha chain | / | 0.450 | |
| 2dqs | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.450 | |
| 2h44 | 7CA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.450 | |
| 2j5s | KTA | Alr4455 protein | / | 0.450 | |
| 2qe4 | JJ3 | Estrogen receptor | / | 0.450 | |
| 2tsc | CB3 | Thymidylate synthase | / | 0.450 | |
| 3btj | DEQ | HTH-type transcriptional regulator QacR | / | 0.450 | |
| 3cth | 319 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.450 | |
| 3eta | 351 | Insulin receptor | 2.7.10.1 | 0.450 | |
| 3fy8 | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3h0a | 9RA | Retinoic acid receptor RXR-alpha | / | 0.450 | |
| 3kk6 | CEL | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.450 | |
| 3nx4 | NAP | Putative oxidoreductase | / | 0.450 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
| 3r3f | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.450 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.450 | |
| 3srr | Q20 | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3sru | Q26 | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3up0 | D7S | aceDAF-12 | / | 0.450 | |
| 3vev | 0H4 | Glucokinase | 2.7.1.2 | 0.450 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.450 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.450 | |
| 4gkt | 0O1 | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.450 | |
| 4ixf | IXF | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4jap | COA | Alpha-pyrone synthesis polyketide synthase-like Pks11 | 2.3.1 | 0.450 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.450 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.450 | |
| 4pd6 | URI | Nucleoside permease | / | 0.450 | |
| 4pv5 | CBW | Lactoylglutathione lyase | 4.4.1.5 | 0.450 | |
| 4rrx | LUR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.450 | |
| 5doz | NDP | JamJ | / | 0.450 | |
| 1fgi | SU1 | Fibroblast growth factor receptor 1 | / | 0.449 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1p7t | ACO | Malate synthase G | / | 0.449 | |
| 1pp9 | SMA | Cytochrome b | / | 0.449 | |
| 1ppj | SMA | Cytochrome b | / | 0.449 | |
| 1rg7 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1t0i | FMN | NAD(P)H-dependent FMN reductase LOT6 | / | 0.449 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.449 | |
| 1xp6 | AIU | Estrogen receptor | / | 0.449 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.449 | |
| 2ay8 | 4TB | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.449 | |
| 2b0q | ADP | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.449 | |
| 2onm | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.449 | |
| 2oyu | IMS | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.449 | |
| 2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.449 | |
| 2pup | ADP | Methylthioribose kinase | 2.7.1.100 | 0.449 | |
| 2qmz | LDP | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.449 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.449 | |
| 3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.449 | |
| 3gco | VAL_TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.449 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 3v1s | 0LH | Strictosidine synthase | 4.3.3.2 | 0.449 | |
| 3zsg | T75 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.449 | |
| 4boe | CLR | Japanin | / | 0.449 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.449 | |
| 4edz | 0O5 | Hematopoietic prostaglandin D synthase | / | 0.449 | |
| 4egn | TWO | Cytochrome P450 | / | 0.449 | |
| 4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.449 | |
| 4gev | CB3 | Thymidylate synthase | / | 0.449 | |
| 4lb2 | DM5 | Serum albumin | / | 0.449 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.449 | |
| 4m2x | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.449 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.449 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.449 | |
| 5bvw | 1N1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.449 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.449 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
| 1frb | ZST | Aldose reductase-related protein 2 | / | 0.448 | |
| 1iiu | RTL | Retinol-binding protein 4 | / | 0.448 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.448 | |
| 1r00 | SAH | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.448 | |
| 1r2j | FAD | FkbI | / | 0.448 | |
| 1rx3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.448 | |
| 1u70 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1uhh | CZP | Aequorin-2 | / | 0.448 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2a8x | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.448 | |
| 2c3q | GTX | Glutathione S-transferase theta-1 | 2.5.1.18 | 0.448 | |
| 2f98 | NGV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.448 | |
| 2gpv | OHT | Estrogen-related receptor gamma | / | 0.448 | |
| 2j4z | 626 | Aurora kinase A | 2.7.11.1 | 0.448 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.448 | |
| 2rku | R78 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.448 | |
| 2w98 | P1Z | Prostaglandin reductase 2 | 1.3.1.48 | 0.448 | |
| 2yiu | SMA | Cytochrome b | / | 0.448 | |
| 2zza | FOL | Dihydrofolate reductase | / | 0.448 | |
| 3f0a | ACO | Spermidine N(1)-acetyltransferase | / | 0.448 | |
| 3gyf | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3ngl | NAP | Bifunctional protein FolD | / | 0.448 | |
| 3o0i | P54 | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.448 | |
| 3r7c | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.448 | |
| 3tea | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.448 | |
| 3tm4 | SAM | Uncharacterized protein | / | 0.448 | |
| 3u2l | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.448 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.448 | |
| 4ea2 | RWZ | Dehydrosqualene synthase | / | 0.448 | |
| 4elh | 53I | Dihydrofolate reductase | / | 0.448 | |
| 4fic | 0UL | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.448 | |
| 4h1j | 0YH | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.448 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.448 | |
| 4htx | 19F | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.448 | |
| 4ixg | IXG | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4iyg | 1HU | Strictosidine synthase | 4.3.3.2 | 0.448 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.448 | |
| 4jva | 1OR | cAMP-dependent protein kinase type II-beta regulatory subunit | / | 0.448 | |
| 4okb | 198 | Androgen receptor | / | 0.448 | |
| 4pl9 | ADP | Ethylene receptor 1 | / | 0.448 | |
| 4qf7 | C0R | Phospholipase A2 VRV-PL-VIIIa | / | 0.448 | |
| 4qoe | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.448 | |
| 4rh1 | 0TT | Spore photoproduct lyase | / | 0.448 | |
| 4twp | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.448 | |
| 4tyj | 0LI | Fibroblast growth factor receptor 4 | 2.7.10.1 | 0.448 | |
| 5emh | NAP | Iridoid synthase | 1.3.1.99 | 0.448 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 1jxz | BCA | 4-chlorobenzoyl coenzyme A dehalogenase | 3.8.1.7 | 0.447 | |
| 1kt3 | RTL | Retinol-binding protein 4 | / | 0.447 | |
| 1m8h | 6NI | Nitric oxide synthase, inducible | 1.14.13.39 | 0.447 | |
| 1ne4 | RP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.447 | |
| 1pt8 | ACO | Formyl-CoA:oxalate CoA-transferase | / | 0.447 | |
| 1vkg | CRI | Histone deacetylase 8 | 3.5.1.98 | 0.447 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.447 | |
| 2gqg | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.447 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.447 | |
| 2npf | MOU | Elongation factor 2 | / | 0.447 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.447 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.447 | |
| 2vez | ACO | Glucosamine 6-phosphate acetyltransferase, putative | / | 0.447 | |
| 2zb1 | GK4 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.447 | |
| 3cxh | SMA | Cytochrome b | / | 0.447 | |
| 3nef | PYV | Abscisic acid receptor PYL1 | / | 0.447 | |
| 3o9l | LPN | Renin | 3.4.23.15 | 0.447 | |
| 3pm0 | BHF | Cytochrome P450 1B1 | / | 0.447 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3qtz | X42 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3t5i | SER_SER_CMT_FAR | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.447 | |
| 3tk0 | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.447 | |
| 3tlj | SAH | Uncharacterized protein | / | 0.447 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.447 | |
| 4a4x | JUP | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.447 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.447 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.447 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.447 | |
| 4knn | E1F | Carbonic anhydrase 13 | 4.2.1.1 | 0.447 | |
| 4mm7 | 29J | Na(+):neurotransmitter symporter (Snf family) | / | 0.447 | |
| 4n4t | 2GV | Tankyrase-1 | 2.4.2.30 | 0.447 | |
| 4o0m | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.447 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.447 | |
| 4qkn | JMS | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.447 | |
| 4uya | AGS | Mitogen-activated protein kinase kinase kinase 21 | 2.7.11.25 | 0.447 | |
| 5cp8 | TCU | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 1cq8 | PY6 | Aspartate aminotransferase | 2.6.1.1 | 0.446 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1ej3 | CZH | Aequorin-2 | / | 0.446 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.446 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1khr | COA | Streptogramin A acetyltransferase | 2.3.1 | 0.446 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.446 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1s9p | DES | Estrogen-related receptor gamma | / | 0.446 | |
| 1t13 | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | / | 0.446 | |
| 1tkz | H16 | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 1typ | NAP | Trypanothione reductase | 1.8.1.12 | 0.446 | |
| 1uio | HPR | Adenosine deaminase | 3.5.4.4 | 0.446 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 2gby | BRN | HTH-type transcriptional regulator QacR | / | 0.446 | |
| 2jiz | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.446 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.446 | |
| 2ph5 | NAD | Homospermidine synthase | / | 0.446 | |
| 2pjl | 047 | Steroid hormone receptor ERR1 | / | 0.446 | |
| 2q3e | UPG | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.446 | |
| 2r3y | VAL_TYR_TRP_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.446 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.446 | |
| 2wpx | ACO | Orf14 | / | 0.446 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.446 | |
| 3a0i | AJI | Glucokinase | 2.7.1.2 | 0.446 | |
| 3aw9 | GDU | NAD-dependent epimerase/dehydratase | / | 0.446 | |
| 3cqe | P91 | Wee1-like protein kinase | 2.7.10.2 | 0.446 | |
| 3d3e | D3E | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 3fl9 | TOP | Dihydrofolate reductase | / | 0.446 | |
| 3g6w | GTP | Uracil phosphoribosyltransferase | 2.4.2.9 | 0.446 | |
| 3iis | PID | Peridinin-chlorophyll a-binding protein 1, chloroplastic | / | 0.446 | |
| 3jw5 | TOP | Dihydrofolate reductase | / | 0.446 | |
| 3mcy | ZH1 | FimH | / | 0.446 | |
| 3r37 | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.446 | |
| 4aos | NAP | Steroid monooxygenase | / | 0.446 | |
| 4az0 | S61 | Lysosomal protective protein | 3.4.16.5 | 0.446 | |
| 4b2w | BZ0 | Glucose-1-phosphate thymidylyltransferase | / | 0.446 | |
| 4dbu | BT9 | Aldo-keto reductase family 1 member C3 | / | 0.446 | |
| 4e70 | N7I | Coniferyl alcohol 9-O-methyltransferase | / | 0.446 | |
| 4eji | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.446 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.446 | |
| 4i3v | NAD | Aldehyde dehydrogenase (NAD+) | / | 0.446 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4mxe | ACO | N-acetyltransferase ESCO1 | 2.3.1 | 0.446 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.446 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.446 | |
| 4uhr | NGI | Adenosine receptor A2a | / | 0.446 | |
| 1d6h | COA | Chalcone synthase 2 | 2.3.1.74 | 0.445 | |
| 1dna | CB3 | Thymidylate synthase | / | 0.445 | |
| 1gs3 | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.445 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.445 | |
| 1sr7 | MOF | Progesterone receptor | / | 0.445 | |
| 1uom | PTI | Estrogen receptor | / | 0.445 | |
| 1xng | DND | NH(3)-dependent NAD(+) synthetase | 6.3.1.5 | 0.445 | |
| 1xpc | AIT | Estrogen receptor | / | 0.445 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.445 | |
| 2cdc | NAP | Glucose 1-dehydrogenase | / | 0.445 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.445 | |
| 2hiw | 7MP | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.445 | |
| 2pnu | ENM | Androgen receptor | / | 0.445 | |
| 2pyw | ADP | Methylthioribose kinase | 2.7.1.100 | 0.445 | |
| 2r6h | FAD | Na(+)-translocating NADH-quinone reductase subunit F | / | 0.445 | |
| 2tsr | D16 | Thymidylate synthase | 2.1.1.45 | 0.445 | |
| 3bgq | VX2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.445 | |
| 3ix9 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3lm4 | HPX | Catechol 2,3-dioxygenase | / | 0.445 | |
| 3nxr | D2D | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3sgl | SAM | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.445 | |
| 3u3o | 3QV | Sulfotransferase 1A1 | 2.8.2.1 | 0.445 | |
| 3w2c | N15 | Aurora kinase A | 2.7.11.1 | 0.445 | |
| 3wxy | COA | Uncharacterized protein | / | 0.445 | |
| 3x04 | GNP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.445 | |
| 3zlm | ANP | Adenosine monophosphate-protein transferase NmFic | 2.7.7.n1 | 0.445 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 4c68 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 4eil | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.445 | |
| 4ezl | 0SE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.445 | |
| 4jd3 | COA | Alpha-pyrone synthesis polyketide synthase-like Pks11 | 2.3.1 | 0.445 | |
| 4l9y | 1VU | L-malyl-CoA/beta-methylmalyl-CoA lyase | 4.1.3.24 | 0.445 | |
| 4o4e | ATP | Kinase | / | 0.445 | |
| 4qi9 | MTX | Dihydrofolate reductase | / | 0.445 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.445 | |
| 5ahk | TPP | Acetolactate synthase II, large subunit | / | 0.445 | |
| 5cyq | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.445 | |
| 1d3g | BRE | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.444 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1fnd | A2P | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.444 | |
| 1kmv | LII | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1lb9 | DNQ | Glutamate receptor 2 | / | 0.444 | |
| 1mj3 | HXC | Enoyl-CoA hydratase, mitochondrial | 4.2.1.17 | 0.444 | |
| 1ndy | FR3 | Adenosine deaminase | 3.5.4.4 | 0.444 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.444 | |
| 1q6s | 214 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.444 | |
| 1qv0 | CZH | Obelin | / | 0.444 | |
| 1qzf | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.444 | |
| 1tll | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.444 | |
| 1w22 | NHB | Histone deacetylase 8 | 3.5.1.98 | 0.444 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 2a8s | GTP | U8 snoRNA-decapping enzyme | / | 0.444 | |
| 2b9w | FAD | Putative aminooxidase | / | 0.444 | |
| 2dr3 | ADP | UPF0273 protein PH0284 | / | 0.444 | |
| 2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.444 | |
| 2ofv | 242 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.444 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.444 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.444 | |
| 2uxh | QUE | HTH-type transcriptional regulator TtgR | / | 0.444 | |
| 2vqq | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.444 | |
| 2wge | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.444 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.444 | |
| 2yix | YIX | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 2zoz | ET | Transcriptional regulator | / | 0.444 | |
| 3c1o | NAP | Eugenol synthase | / | 0.444 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3fsu | C2F | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.444 | |
| 3gst | GPR | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.444 | |
| 3k45 | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 3sgy | 06W | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3vso | EK1 | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 3vw8 | DF6 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.444 | |
| 3w2o | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.444 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.444 | |
| 3wy0 | COA | Uncharacterized protein | / | 0.444 | |
| 4a4l | 939 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.444 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.444 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.444 | |
| 4gcx | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.444 | |
| 4kw5 | 1W6 | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.444 | |
| 4l98 | LRG | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 4nie | DMX | Nuclear receptor ROR-gamma | / | 0.444 | |
| 4okt | 198 | Androgen receptor | / | 0.444 | |
| 4tqq | UQ1 | Reaction center protein L chain | / | 0.444 | |
| 4x7y | SAH | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.444 | |
| 1ddu | CB3 | Thymidylate synthase | / | 0.443 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 1eqh | FLP | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.443 | |
| 1fm9 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.443 | |
| 1ht8 | 34C | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.443 | |
| 1kt6 | RTL | Retinol-binding protein 4 | / | 0.443 | |
| 1mjh | ATP | Universal stress protein MJ0577 | / | 0.443 | |
| 1nhz | 486 | Glucocorticoid receptor | / | 0.443 | |
| 1owo | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.443 | |
| 1pxx | DIF | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.443 | |
| 1rpw | DID | HTH-type transcriptional regulator QacR | / | 0.443 | |
| 1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 2ayl | FLP | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.443 | |
| 2ayr | L4G | Estrogen receptor | / | 0.443 | |
| 2gn9 | UPG | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.443 | |
| 2iog | IOG | Estrogen receptor | / | 0.443 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.443 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.443 | |
| 2trs | IPL | Tryptophan synthase alpha chain | / | 0.443 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.443 | |
| 2wqb | QQ1 | Angiopoietin-1 receptor | 2.7.10.1 | 0.443 | |
| 2x7g | PVB | SRSF protein kinase 2 | 2.7.11.1 | 0.443 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.443 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.443 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta | / | 0.443 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta' | / | 0.443 | |
| 3f5p | 741 | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.443 | |
| 4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.443 | |
| 4kao | KAO | Focal adhesion kinase 1 | 2.7.10.2 | 0.443 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.443 | |
| 4mrx | CZH | Obelin | / | 0.443 | |
| 4oma | LCS | Methionine gamma-lyase | / | 0.443 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.443 | |
| 4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.443 | |
| 4xr9 | TMP | CalS8 | / | 0.443 | |
| 5bsr | COA | 4-coumarate--CoA ligase 2 | 6.2.1.12 | 0.443 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.443 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 2fjm | 073 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.442 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.442 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.442 | |
| 2pir | DHT | Androgen receptor | / | 0.442 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2puu | G2G | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 2wet | FAD | Tryptophan 5-halogenase | / | 0.442 | |
| 2xk3 | XK3 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.442 | |
| 2yhu | WHF | Pteridine reductase | / | 0.442 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3hfb | ML4 | Tryptophan 5-hydroxylase 1 | 1.14.16.4 | 0.442 | |
| 3ia4 | MTX | Dihydrofolate reductase | / | 0.442 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.442 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.442 | |
| 3nn6 | HNK | 6-hydroxy-L-nicotine oxidase | / | 0.442 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.442 | |
| 3ntg | D72 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.442 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.442 | |
| 3p5k | P5K | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3p6n | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3q2m | CKI | Spectinomycin phosphotransferase | / | 0.442 | |
| 3q7d | NPX | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.442 | |
| 3r32 | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.442 | |
| 3sgt | P09 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | / | 0.442 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.442 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.442 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.442 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.442 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 4ez7 | 2AN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 4h2n | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.442 | |
| 4h4m | 494 | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4ih3 | PDC | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase | 4.1.1.45 | 0.442 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.442 | |
| 4n8i | COA | Putative 4-hydroxybutyrate coenzyme A transferase | / | 0.442 | |
| 4qjq | OTR | Lactoperoxidase | / | 0.442 | |
| 5cds | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.442 | |
| 5d7p | AR6 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.442 | |
| 1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1ee0 | CAA | 2-pyrone synthase | / | 0.441 | |
| 1kzi | THG | Thymidylate synthase | / | 0.441 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.441 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.441 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.441 | |
| 1qnf | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.441 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 1s36 | CEI | Obelin | / | 0.441 | |
| 1xu7 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 2ati | IHU | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.441 | |
| 2c7g | FAD | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.441 | |
| 2cy2 | ACO | Probable acetyltransferase | / | 0.441 | |
| 2fk8 | SAM | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.441 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.441 | |
| 2h12 | CMX | Citrate synthase | / | 0.441 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2vqo | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.441 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.441 | |
| 2yat | EEU | Estrogen receptor | / | 0.441 | |
| 2ydf | IO3 | Serum albumin | / | 0.441 | |
| 2z2w | 770 | Wee1-like protein kinase | 2.7.10.2 | 0.441 | |
| 3be2 | RAJ | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.441 | |
| 3blo | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.441 | |
| 3cx4 | ADP | Glycogen synthase | 2.4.1.21 | 0.441 | |
| 3fpk | FAD | Ferredoxin-NADP reductase | / | 0.441 | |
| 3gcn | TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.441 | |
| 3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3gph | OID | Cytochrome P450 2E1 | 1.14.13 | 0.441 | |
| 3id8 | MRK | Glucokinase | 2.7.1.2 | 0.441 | |
| 3ipu | O40 | Oxysterols receptor LXR-alpha | / | 0.441 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.441 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.441 | |
| 3nwl | NDP | Catalase | 1.11.1.6 | 0.441 | |
| 3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3sh0 | SAX | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.441 | |
| 3tmz | 06X | Cytochrome P450 2B4 | 1.14.14.1 | 0.441 | |
| 3w0t | HPU | Lactoylglutathione lyase | 4.4.1.5 | 0.441 | |
| 3zkp | ERB | Erythromycin C-12 hydroxylase | 1.14.13.154 | 0.441 | |
| 4a7c | E46 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 4b1f | KRH | Glutamate racemase | / | 0.441 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.441 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.441 | |
| 4li7 | 1XP | Tankyrase-1 | 2.4.2.30 | 0.441 | |
| 4mmd | 29E | Na(+):neurotransmitter symporter (Snf family) | / | 0.441 | |
| 4ojb | 198 | Androgen receptor | / | 0.441 | |
| 4phl | PIL | Phosphodiesterase | / | 0.441 | |
| 5bv3 | M7G | m7GpppX diphosphatase | 3.6.1.59 | 0.441 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.441 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.441 | |
| 1a27 | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1bve | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.440 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.440 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1lhw | ESM | Sex hormone-binding globulin | / | 0.440 | |
| 1nqm | BTN | Streptavidin | / | 0.440 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.440 | |
| 1s1v | TNK | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 1vrq | FON | Subunit alpha of sarocosine oxidase | / | 0.440 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
| 1ysx | 4EB | Serum albumin | / | 0.440 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2b36 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2hko | FAD | Lysine-specific histone demethylase 1A | 1 | 0.440 | |
| 2j0v | GDP | Rac-like GTP-binding protein ARAC7 | / | 0.440 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.440 | |
| 2kce | D16 | Thymidylate synthase | / | 0.440 | |
| 2q4w | FAD | Cytokinin dehydrogenase 7 | 1.5.99.12 | 0.440 | |
| 2vq5 | LDP | S-norcoclaurine synthase | / | 0.440 | |
| 2wks | CB6 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.440 | |
| 2xk4 | OL2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.440 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 2zd1 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 3dqw | AGS | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.440 | |
| 3drr | R8E | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 3dya | PZL | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3lan | KBT | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.440 | |
| 3q0g | COA | Probable enoyl-CoA hydratase echA8 | 4.2.1.17 | 0.440 | |
| 3t0k | DCQ | Sulfide-quinone reductase | / | 0.440 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.440 | |
| 3uic | 09T | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 | |
| 4b13 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4b5b | BBE | Glucose-1-phosphate thymidylyltransferase | / | 0.440 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4c2z | 646 | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.440 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.440 | |
| 4cx3 | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.440 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 4gkh | 0J9 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.440 | |
| 4hqv | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.440 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.440 | |
| 4ivy | 1GT | Estrogen receptor | / | 0.440 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.440 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.440 | |
| 4jvn | YUG | Estrogen sulfotransferase | 2.8.2.4 | 0.440 | |
| 4kd7 | 9DR | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4la0 | 198 | Serum albumin | / | 0.440 | |
| 4mlh | VO2 | Glucokinase | 2.7.1.2 | 0.440 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.440 | |
| 5c8a | 5AD | Probable transcriptional regulator | / | 0.440 | |
| 5d7q | AR6 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.440 | |
| 3p0g | P0G | Beta-2 adrenergic receptor | / | 0.440 |