Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1sl3 | 170 | Prothrombin | 3.4.21.5 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1sl3 | 170 | Prothrombin | 3.4.21.5 | 1.000 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.679 | |
| 1zrb | 062 | Prothrombin | 3.4.21.5 | 0.674 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.660 | |
| 4bam | MM9 | Prothrombin | 3.4.21.5 | 0.654 | |
| 2zdv | 37U | Prothrombin | 3.4.21.5 | 0.636 | |
| 2zgx | 29U | Prothrombin | 3.4.21.5 | 0.622 | |
| 3eq0 | 2TS | Prothrombin | 3.4.21.5 | 0.620 | |
| 1ypj | UIB | Prothrombin | 3.4.21.5 | 0.618 | |
| 2zff | 53U | Prothrombin | 3.4.21.5 | 0.618 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.618 | |
| 2znk | 31U | Prothrombin | 3.4.21.5 | 0.611 | |
| 3egk | M18 | Prothrombin | 3.4.21.5 | 0.610 | |
| 1o0d | 163 | Prothrombin | 3.4.21.5 | 0.608 | |
| 1xm1 | GAH | Prothrombin | 3.4.21.5 | 0.605 | |
| 1c5n | ESI | Prothrombin | 3.4.21.5 | 0.604 | |
| 4bah | MEL | Prothrombin | 3.4.21.5 | 0.603 | |
| 2zfp | 19U | Prothrombin | 3.4.21.5 | 0.602 | |
| 2ziq | 26U | Prothrombin | 3.4.21.5 | 0.601 | |
| 4bak | M67 | Prothrombin | 3.4.21.5 | 0.592 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.591 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.589 | |
| 1kts | C24 | Prothrombin | 3.4.21.5 | 0.586 | |
| 2a2x | NA9 | Prothrombin | 3.4.21.5 | 0.581 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.576 | |
| 1ae8 | AZL | Prothrombin | 3.4.21.5 | 0.575 | |
| 3biu | 10U | Prothrombin | 3.4.21.5 | 0.574 | |
| 3dhk | 23U | Prothrombin | 3.4.21.5 | 0.571 | |
| 3f68 | 91U | Prothrombin | 3.4.21.5 | 0.570 | |
| 1ta2 | 176 | Prothrombin | 3.4.21.5 | 0.565 | |
| 2zg0 | 50U | Prothrombin | 3.4.21.5 | 0.565 | |
| 1ghv | 120 | Prothrombin | 3.4.21.5 | 0.564 | |
| 1ypm | RA4 | Prothrombin | 3.4.21.5 | 0.562 | |
| 1vzq | SHY | Prothrombin | 3.4.21.5 | 0.560 | |
| 3biv | 11U | Prothrombin | 3.4.21.5 | 0.559 | |
| 1mu8 | CDB | Prothrombin | 3.4.21.5 | 0.558 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.558 | |
| 2zhq | 27U | Prothrombin | 3.4.21.5 | 0.553 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.551 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.550 | |
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 0.547 | |
| 1afe | ALZ | Prothrombin | 3.4.21.5 | 0.543 | |
| 1c4v | IH2 | Prothrombin | 3.4.21.5 | 0.542 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.541 | |
| 3dux | 64U | Prothrombin | 3.4.21.5 | 0.541 | |
| 1iqg | XME | Coagulation factor X | 3.4.21.6 | 0.536 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.535 | |
| 2uuj | 896 | Prothrombin | 3.4.21.5 | 0.534 | |
| 2vh0 | GSI | Coagulation factor X | 3.4.21.6 | 0.534 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.530 | |
| 4e2w | JHZ | Methyltransferase | / | 0.530 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.527 | |
| 1nfy | RTR | Coagulation factor X | 3.4.21.6 | 0.526 | |
| 2cn0 | F25 | Prothrombin | 3.4.21.5 | 0.526 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.525 | |
| 1w7g | MIU | Prothrombin | 3.4.21.5 | 0.524 | |
| 4fui | UI3 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.524 | |
| 1iqh | XMF | Coagulation factor X | 3.4.21.6 | 0.523 | |
| 1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.522 | |
| 2cji | GSK | Coagulation factor X | 3.4.21.6 | 0.522 | |
| 4ban | M6S | Prothrombin | 3.4.21.5 | 0.522 | |
| 4e2x | TYD | Methyltransferase | / | 0.520 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.511 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.509 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.509 | |
| 2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.509 | |
| 4hfp | 15U | Prothrombin | 3.4.21.5 | 0.509 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.509 | |
| 4i13 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.508 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.507 | |
| 4e31 | JHZ | Methyltransferase | / | 0.507 | |
| 4e32 | DWN | Methyltransferase | / | 0.507 | |
| 4ho6 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.506 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.505 | |
| 3v0x | ANH | Cationic trypsin | 3.4.21.4 | 0.505 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.504 | |
| 1ypk | CCR | Prothrombin | 3.4.21.5 | 0.504 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.504 | |
| 1nt1 | T76 | Prothrombin | 3.4.21.5 | 0.503 | |
| 1uvs | I11 | Prothrombin | 3.4.21.5 | 0.503 | |
| 3sor | O58 | Coagulation factor XI | 3.4.21.27 | 0.502 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.501 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.500 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.500 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.500 | |
| 4baq | M4Z | Prothrombin | 3.4.21.5 | 0.500 | |
| 1vgq | CAO | Formyl-CoA:oxalate CoA-transferase | / | 0.499 | |
| 3uku | C69 | Actin-related protein 3 | / | 0.498 | |
| 4fuf | 8UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.497 | |
| 5e7o | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.497 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.495 | |
| 3a6q | FMN | FMN-binding protein | / | 0.495 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.495 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.494 | |
| 1ny2 | ARG_PRO_PRO_GLY | Prothrombin | 3.4.21.5 | 0.494 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.494 | |
| 3v2u | ATP | Protein GAL3 | / | 0.494 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.493 | |
| 4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.493 | |
| 4x5h | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.493 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.492 | |
| 1nfx | RDR | Coagulation factor X | 3.4.21.6 | 0.491 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.491 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.491 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.491 | |
| 3kqe | LGM | Coagulation factor X | 3.4.21.6 | 0.491 | |
| 4de2 | DN3 | Beta-lactamase | / | 0.491 | |
| 4j1e | 1HM | Beta-secretase 1 | 3.4.23.46 | 0.491 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.491 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.490 | |
| 3ndj | JHZ | Methyltransferase | / | 0.490 | |
| 4qt3 | RAP | Peptidylprolyl isomerase | / | 0.490 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.489 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.489 | |
| 2qiq | CYV | Replicase polyprotein 1ab | / | 0.489 | |
| 4fub | 4UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.489 | |
| 4fuj | 1U9 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.489 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.489 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.489 | |
| 1j78 | VDY | Vitamin D-binding protein | / | 0.488 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.488 | |
| 2g20 | L1A | Renin | 3.4.23.15 | 0.488 | |
| 2gfx | PMN | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.488 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.488 | |
| 1p0y | SAH | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.487 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.487 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.487 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.487 | |
| 4cgh | LOZ | Integrase | / | 0.487 | |
| 4z4p | SAH | Histone-lysine N-methyltransferase 2D | 2.1.1.43 | 0.487 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.486 | |
| 4btu | 6XS | Coagulation factor X | 3.4.21.6 | 0.486 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.486 | |
| 1bl4 | AP1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.485 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
| 1mq6 | XLD | Coagulation factor X | 3.4.21.6 | 0.485 | |
| 1yqs | BSA | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.485 | |
| 2pgt | GPR | Glutathione S-transferase P | 2.5.1.18 | 0.485 | |
| 4fm8 | 0UQ | Beta-secretase 1 | 3.4.23.46 | 0.485 | |
| 1gpe | FAD | Glucose oxidase | 1.1.3.4 | 0.484 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.484 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.484 | |
| 3e6e | DCS | Alanine racemase | / | 0.484 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.484 | |
| 3qtv | 06P | Prothrombin | 3.4.21.5 | 0.484 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.484 | |
| 4e2z | JHZ | Methyltransferase | / | 0.484 | |
| 4f9g | C2E | Stimulator of interferon genes protein | / | 0.484 | |
| 4loy | 6XS | Prothrombin | 3.4.21.5 | 0.484 | |
| 4x7v | MIV | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.484 | |
| 1h62 | ANB | Pentaerythritol tetranitrate reductase | / | 0.483 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.483 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.483 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.483 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.483 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.483 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.482 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.482 | |
| 2bxt | C2D | Prothrombin | 3.4.21.5 | 0.482 | |
| 2gtb | AZP | Orf1ab polyprotein | / | 0.482 | |
| 2p3u | 663 | Coagulation factor X | 3.4.21.6 | 0.482 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.482 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.482 | |
| 1iki | REY | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.481 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.481 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.481 | |
| 4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.481 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.481 | |
| 1f92 | UKP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.480 | |
| 1ra3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.480 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.480 | |
| 1qpf | 858 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.479 | |
| 1v45 | 3DG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.479 | |
| 2cv1 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.479 | |
| 4bao | MVF | Prothrombin | 3.4.21.5 | 0.479 | |
| 4cfa | WOP | Integrase | / | 0.479 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.479 | |
| 1lqd | CMI | Coagulation factor X | 3.4.21.6 | 0.478 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.478 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.478 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.478 | |
| 2ohv | NHL | Glutamate racemase | / | 0.478 | |
| 3hlw | CE3 | Beta-lactamase | / | 0.478 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.478 | |
| 3jyq | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.478 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.478 | |
| 4dz2 | FK5 | Peptidyl-prolyl cis-trans isomerase | / | 0.478 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.478 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.477 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.477 | |
| 2v8p | CDP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.477 | |
| 2y5h | Y5H | Coagulation factor X | 3.4.21.6 | 0.477 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.477 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.477 | |
| 1fkb | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.476 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.476 | |
| 1h65 | GDP | Translocase of chloroplast 34 | 3.6.5 | 0.476 | |
| 2e07 | SAH | Diphthine synthase | / | 0.476 | |
| 2h2j | SFG | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.476 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.476 | |
| 2ofi | ADK | 3-methyladenine DNA glycosylase I | / | 0.476 | |
| 2pja | 33Z | Carboxypeptidase B | / | 0.476 | |
| 2z95 | NDP | GDP-mannose 4,6-dehydratase | / | 0.476 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.476 | |
| 3w3n | RX8 | Toll-like receptor 8 | / | 0.476 | |
| 4bek | XK0 | Beta-secretase 1 | 3.4.23.46 | 0.476 | |
| 4btt | VYR | Coagulation factor X | 3.4.21.6 | 0.476 | |
| 4de3 | DN8 | Beta-lactamase | / | 0.476 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.476 | |
| 4fud | 6UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.476 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.476 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.476 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.475 | |
| 2dg3 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.475 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.475 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.475 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.475 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.475 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.475 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.475 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.475 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.475 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.475 | |
| 4ddy | DN6 | Beta-lactamase | / | 0.475 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.474 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.474 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.474 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.474 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.474 | |
| 3lzx | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.474 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.474 | |
| 4ira | FAD | 4-hydroxyphenylacetate 3-monooxygenase | / | 0.474 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.474 | |
| 4rn6 | 15U | Prothrombin | 3.4.21.5 | 0.474 | |
| 4yfy | 0FX | VioF | / | 0.474 | |
| 5bnw | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.474 | |
| 1a4w | QWE | Prothrombin | 3.4.21.5 | 0.473 | |
| 1gw2 | FER | Peroxidase C1A | 1.11.1.7 | 0.473 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.473 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.473 | |
| 3eku | CY9 | Actin-5C | / | 0.473 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.473 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.473 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.473 | |
| 4e7r | 0NW | Prothrombin | 3.4.21.5 | 0.473 | |
| 4i0j | 842 | Beta-secretase 1 | 3.4.23.46 | 0.473 | |
| 4lay | I63 | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.473 | |
| 4wxg | 2BO | Serine hydroxymethyltransferase | / | 0.473 | |
| 1rx6 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.472 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.472 | |
| 2p8h | MY9 | Beta-secretase 1 | 3.4.23.46 | 0.472 | |
| 2y82 | 930 | Coagulation factor X | 3.4.21.6 | 0.472 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.472 | |
| 3o7b | SAH | Ribosomal RNA small subunit methyltransferase Nep1 | / | 0.472 | |
| 4az2 | 9MU | Prothrombin | 3.4.21.5 | 0.472 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.472 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.472 | |
| 5cyo | GDP | Septin-9 | / | 0.472 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.471 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 1i24 | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.471 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.471 | |
| 1rx5 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 1vji | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.471 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.471 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.471 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.471 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 3e39 | FMN | Nitroreductase | / | 0.471 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.471 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 4drm | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.471 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.471 | |
| 1ozv | SAH | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.470 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.470 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.470 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.470 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.470 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.470 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.470 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.470 | |
| 3gy9 | COA | GCN5-related N-acetyltransferase | / | 0.470 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.470 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.470 | |
| 3qgi | 33F | Genome polyprotein | 2.7.7.48 | 0.470 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.470 | |
| 4azy | 7F3 | Beta-secretase 1 | 3.4.23.46 | 0.470 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.470 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.470 | |
| 4de1 | 0J6 | Beta-lactamase | / | 0.470 | |
| 4ej1 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 1fxu | GU7 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.469 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.469 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.469 | |
| 1wn3 | HXC | Phenylacetic acid degradation protein PaaI | / | 0.469 | |
| 2dxi | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.469 | |
| 2viy | VG3 | Beta-secretase 1 | 3.4.23.46 | 0.469 | |
| 2x6o | 2TC | Tetracycline repressor protein class D | / | 0.469 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 3sxj | SAM | Putative methyltransferase | / | 0.469 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.469 | |
| 4mwh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.469 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.469 | |
| 1b5e | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.468 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.468 | |
| 1qpl | 587 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.468 | |
| 2cnd | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.468 | |
| 2d1o | FA4 | Stromelysin-1 | 3.4.24.17 | 0.468 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.468 | |
| 3ebl | GA4 | Gibberellin receptor GID1 | / | 0.468 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.468 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.468 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.468 | |
| 3wqu | ATP | Cell division protein FtsA | / | 0.468 | |
| 4b1e | 6T6 | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.468 | |
| 4bti | 7R9 | Coagulation factor X | 3.4.21.6 | 0.468 | |
| 4dkv | 0KW | Envelope glycoprotein gp160 | / | 0.468 | |
| 4fi1 | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.468 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.468 | |
| 1ege | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.467 | |
| 1mew | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.467 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.467 | |
| 1rkw | PNT | HTH-type transcriptional regulator QacR | / | 0.467 | |
| 2a5h | SAM | L-lysine 2,3-aminomutase | 5.4.3.2 | 0.467 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 2ol0 | DUD | DUTP pyrophosphatase | / | 0.467 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.467 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.467 | |
| 4hs4 | FMN | Chromate reductase | / | 0.467 | |
| 4i1c | 1BE | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 4jiq | 1L5 | GTN Reductase | / | 0.467 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.466 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.466 | |
| 1vyq | DUX | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.466 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.466 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.466 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.466 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.466 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.466 | |
| 3a20 | FMN | FMN-binding protein | / | 0.466 | |
| 3a6r | FMN | FMN-binding protein | / | 0.466 | |
| 3g0c | RUF | Dipeptidyl peptidase 4 | / | 0.466 | |
| 3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.466 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.466 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 4hn1 | TYD | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.466 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.465 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.465 | |
| 2ewv | ADP | Twitching motility protein PilT | / | 0.465 | |
| 2vjm | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.465 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.465 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.465 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.465 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.465 | |
| 3w77 | FMN | FMN-dependent NADH-azoreductase | / | 0.465 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.465 | |
| 4i10 | 1BS | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 4jfi | 1KT | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.465 | |
| 4qx5 | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.465 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.464 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.464 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.464 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.464 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.464 | |
| 3gwd | NAP | Cyclohexanone monooxygenase | / | 0.464 | |
| 3mt8 | 17T | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.464 | |
| 3oia | A31 | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.464 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 4i0f | 1BF | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 4l7v | SAH | Protein-L-isoaspartate O-methyltransferase | / | 0.464 | |
| 4zwm | PLP | Ornithine aminotransferase, mitochondrial, putative | / | 0.464 | |
| 1kw0 | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.463 | |
| 1lpk | CBB | Coagulation factor X | 3.4.21.6 | 0.463 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.463 | |
| 1wli | FMN | FMN-binding protein | / | 0.463 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.463 | |
| 2d0k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.463 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.463 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.463 | |
| 2ptf | FMN | Uncharacterized protein MTH_863 | / | 0.463 | |
| 2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 2ylr | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.463 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.463 | |
| 3esy | FMN | Flavodoxin | / | 0.463 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.463 | |
| 3p17 | 99P | Prothrombin | 3.4.21.5 | 0.463 | |
| 3plp | BBA | Cationic trypsin | 3.4.21.4 | 0.463 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.463 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.463 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.463 | |
| 4lv5 | ADP | Rhoptry protein 5B | / | 0.463 | |
| 4nhm | UN9 | Prolyl 3,4-dihydroxylase TPA1 | 1.14.11 | 0.463 | |
| 1bzf | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.462 | |
| 1j4h | SUB | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.462 | |
| 1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.462 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.462 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.462 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.462 | |
| 2iby | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.462 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.462 | |
| 3bnk | FMN | Flavoredoxin | / | 0.462 | |
| 3cos | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.462 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.462 | |
| 3dzi | RGT | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.462 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 3jv7 | NAD | Secondary alcohol dehydrogenase | / | 0.462 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.462 | |
| 3vy2 | FMN | FMN-binding protein | / | 0.462 | |
| 4b1j | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.462 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1fkl | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.461 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.461 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.461 | |
| 2e08 | SAH | Diphthine synthase | / | 0.461 | |
| 2fk8 | SAM | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.461 | |
| 2g00 | 4QC | Coagulation factor X | 3.4.21.6 | 0.461 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.461 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.461 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.461 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.461 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.461 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.461 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.461 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.460 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.460 | |
| 1riw | OSC | Prothrombin | 3.4.21.5 | 0.460 | |
| 1u71 | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 2b8v | 3BN | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.460 | |
| 2j34 | GS6 | Coagulation factor X | 3.4.21.6 | 0.460 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.460 | |
| 3fpj | SAM | Uncharacterized protein | / | 0.460 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.460 | |
| 3n14 | FMN | Xenobiotic reductase | / | 0.460 | |
| 3qto | 10P | Prothrombin | 3.4.21.5 | 0.460 | |
| 3qwp | SAM | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.460 | |
| 3vsx | R32 | Renin | 3.4.23.15 | 0.460 | |
| 3wt0 | ATP | Cell division protein FtsA | / | 0.460 | |
| 3zhr | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.460 | |
| 4h0v | NAD | Iota toxin component Ia | / | 0.460 | |
| 5czy | SAM | Eukaryotic huntingtin interacting protein B | / | 0.460 | |
| 1a8r | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.459 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.459 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.459 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.459 | |
| 2owf | SAH | Diphthine synthase | / | 0.459 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.459 | |
| 3g11 | P9C | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.459 | |
| 3g2l | LEW | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.459 | |
| 3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.459 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.459 | |
| 3t0i | SAH | Putative methyltransferase | / | 0.459 | |
| 3w5h | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.459 | |
| 3zks | WZV | Beta-secretase 2 | 3.4.23.45 | 0.459 | |
| 3zov | WZV | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 4c4o | NAD | SADH | / | 0.459 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.459 | |
| 4eu8 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.459 | |
| 4hmx | FMN | Pyridoxamine 5'-phosphate oxidase | / | 0.459 | |
| 4wxf | PLG | Serine hydroxymethyltransferase | / | 0.459 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.458 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.458 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.458 | |
| 1p5r | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.458 | |
| 1q6i | FK5 | FKBP-type peptidyl-prolyl cis-trans isomerase FkpA | 5.2.1.8 | 0.458 | |
| 1v2h | GUN | Purine nucleoside phosphorylase | 2.4.2.1 | 0.458 | |
| 1vja | 7IN | Urokinase-type plasminogen activator | 3.4.21.73 | 0.458 | |
| 1w13 | SM1 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.458 | |
| 1ywg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.458 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.458 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 2fs4 | PZ1 | Renin | 3.4.23.15 | 0.458 | |
| 2fzm | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.458 | |
| 2h2e | SA8 | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.458 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.458 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.458 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.458 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.458 | |
| 4bmp | FMN | Protein NrdI | / | 0.458 | |
| 4brg | GNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.458 | |
| 4drk | I63 | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.458 | |
| 4eu4 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.458 | |
| 4j4n | D44 | Peptidylprolyl isomerase | / | 0.458 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.458 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.458 | |
| 8dfr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1jdv | ADN | Purine nucleoside phosphorylase | / | 0.457 | |
| 1lc3 | NAD | Biliverdin reductase A | 1.3.1.24 | 0.457 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.457 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.457 | |
| 2dg4 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.457 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 3ex8 | AIF | Riboflavin biosynthesis protein RibD | 1.1.1.193 | 0.457 | |
| 3mkn | DNB | Pyrimidine-specific ribonucleoside hydrolase RihB | / | 0.457 | |
| 4gcm | NAP | Thioredoxin reductase | 1.8.1.9 | 0.457 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.457 | |
| 4h4e | 10G | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | / | 0.457 | |
| 4l7h | 1W1 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4utl | FNR | Xenobiotic reductase | / | 0.457 | |
| 4xyb | NDP | Formate dehydrogenase | / | 0.457 | |
| 5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1bkf | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.456 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.456 | |
| 1xh7 | R96 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.456 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.456 | |
| 2g0b | NLT | Long-chain N-acyl amino acid synthase | / | 0.456 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.456 | |
| 3b9x | NOS | Pyrimidine-specific ribonucleoside hydrolase RihB | 3.2.2.8 | 0.456 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.456 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.456 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.456 | |
| 3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.456 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.456 | |
| 4img | NGF | N-acetylneuraminate lyase | / | 0.456 | |
| 4j1k | 1HG | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 4pgh | SAM | Caffeic acid O-methyltransferase | / | 0.456 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.456 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.455 | |
| 1m4i | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.455 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.455 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.455 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.455 | |
| 2gz8 | F3F | Orf1a polyprotein | / | 0.455 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.455 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.455 | |
| 2rfi | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.455 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.455 | |
| 3ag6 | PAJ | Pantothenate synthetase | / | 0.455 | |
| 3c8b | ARG_ARG_GLY_ILE_NH2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.455 | |
| 3i25 | MV7 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 3n4l | 842 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 3o5r | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.455 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.455 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.455 | |
| 3rdq | DTB | Streptavidin | / | 0.455 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.455 | |
| 3tqa | NDP | Dihydrofolate reductase | / | 0.455 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.455 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.455 | |
| 4h4c | 10D | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | / | 0.455 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.455 | |
| 5c4c | UPG | Histo-blood group ABO system transferase | / | 0.455 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.454 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1n3s | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.454 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.454 | |
| 1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.454 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.454 | |
| 1z6l | FAD | Polyamine oxidase FMS1 | / | 0.454 | |
| 2a8h | 4NH | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.454 | |
| 2a8y | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.454 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.454 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.454 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.454 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.454 | |
| 3bw2 | FMN | Putative 2-nitropropane dioxygenase | / | 0.454 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.454 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3eks | CY9 | Actin-5C | / | 0.454 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.454 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 3t64 | DU3 | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.454 | |
| 3t70 | DU4 | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.454 | |
| 3u78 | E67 | Lysine-specific demethylase 7A | 1.14.11 | 0.454 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.454 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.454 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.454 | |
| 4i0z | 1BB | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4la7 | A1O | Abscisic acid receptor PYL2 | / | 0.454 | |
| 5c4f | UPG | Histo-blood group ABO system transferase | / | 0.454 | |
| 1lvu | 9PP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.453 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.453 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.453 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.453 | |
| 2j2p | SC2 | Ficolin-2 | / | 0.453 | |
| 2wqp | WQP | Polysialic acid capsule biosynthesis protein SiaC | / | 0.453 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.453 | |
| 2xfj | VG5 | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.453 | |
| 3ea5 | GDP | GTP-binding nuclear protein Ran | / | 0.453 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.453 | |
| 3ho2 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.453 | |
| 3n19 | FNR | Xenobiotic reductase | / | 0.453 | |
| 3o76 | GTB | Glutathione S-transferase P 1 | 2.5.1.18 | 0.453 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.453 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.453 | |
| 4c13 | UML | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase | / | 0.453 | |
| 4s1h | ADP | Pyridoxal kinase, putative | / | 0.453 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.453 | |
| 5ex0 | SAH | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.453 | |
| 1dgm | ADN | Adenosine kinase | 2.7.1.20 | 0.452 | |
| 1f0y | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.452 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.452 | |
| 1n77 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.452 | |
| 1owi | 426 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.452 | |
| 1yry | MSG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.452 | |
| 2oeg | UPG | UDP-glucose pyrophosphorylase | / | 0.452 | |
| 2pam | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.452 | |
| 2pcg | SAH | Diphthine synthase | / | 0.452 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.452 | |
| 2w2v | GTP | Ras-related C3 botulinum toxin substrate 2 | / | 0.452 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.452 | |
| 3rdo | BTN | Streptavidin | / | 0.452 | |
| 3toz | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.452 | |
| 4b67 | NAP | L-ornithine N(5)-monooxygenase | / | 0.452 | |
| 4bfd | 8T3 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.452 | |
| 4ewo | 996 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.452 | |
| 4wrk | DUP | DUTPase | / | 0.452 | |
| 5fwn | NAP | Putative dehydrogenase | / | 0.452 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.451 | |
| 1h2b | NAJ | NAD-dependent alcohol dehydrogenase | / | 0.451 | |
| 1jdt | MTA | Purine nucleoside phosphorylase | / | 0.451 | |
| 1lrj | UD1 | UDP-glucose 4-epimerase | 5.1.3.2 | 0.451 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.451 | |
| 2bbw | GP5 | Adenylate kinase 4, mitochondrial | / | 0.451 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.451 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.451 | |
| 2jsd | NGH | Matrix metalloproteinase-20 | 3.4.24 | 0.451 | |
| 2std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.451 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.451 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.451 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.451 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.451 | |
| 3juq | AJD | Phenazine biosynthesis protein A/B | / | 0.451 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.451 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.451 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.451 | |
| 3myt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.451 | |
| 3rzp | PRF | NADPH-dependent 7-cyano-7-deazaguanine reductase | / | 0.451 | |
| 3t3i | GPW | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.451 | |
| 4b78 | KGG | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4chy | C5Q | Integrase | / | 0.451 | |
| 4cjs | L0Y | Integrase | / | 0.451 | |
| 4cnf | MTA | SpoU rRNA methylase | / | 0.451 | |
| 4f7i | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.451 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.451 | |
| 4kl1 | PCG | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.451 | |
| 4uth | FMN | Xenobiotic reductase | / | 0.451 | |
| 4x5i | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4yj2 | GTP | Tubulin alpha-1B chain | / | 0.451 | |
| 5jhn | SAM | Histone-lysine N-methyltransferase EHMT2 | / | 0.451 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1dyh | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1eir | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.450 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.450 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.450 | |
| 1owe | 675 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.450 | |
| 1rc4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1u2y | GOX | Pancreatic alpha-amylase | / | 0.450 | |
| 1x27 | ASP_ASP_TYR_VAL_PTR | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.450 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.450 | |
| 2dg9 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.450 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.450 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.450 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2j4k | U5P | Uridylate kinase | 2.7.4.22 | 0.450 | |
| 2oaz | I96 | Methionine aminopeptidase 2 | / | 0.450 | |
| 2p4s | DIH | AGAP005945-PA | / | 0.450 | |
| 2q96 | A18 | Methionine aminopeptidase | / | 0.450 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.450 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.450 | |
| 2tct | CTC | Tetracycline repressor protein class D | / | 0.450 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 3amt | ATP | tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS | 6.3.4.22 | 0.450 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3e8x | NAP | BH1520 protein | / | 0.450 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.450 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.450 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.450 | |
| 4dh0 | MR8 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.450 | |
| 4e2d | FMN | Dehydrogenase | / | 0.450 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.450 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.450 | |
| 4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.450 | |
| 4xrb | NDP | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.450 | |
| 1bwk | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.449 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.449 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.449 | |
| 1fkg | SB3 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.449 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.449 | |
| 1lv8 | 9PP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.449 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.449 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.449 | |
| 2dek | SAH | Diphthine synthase | / | 0.449 | |
| 2ejk | SAH | Diphthine synthase | / | 0.449 | |
| 2q28 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.449 | |
| 2r8o | T5X | Transketolase 1 | / | 0.449 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.449 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2xpw | OTC | Tetracycline repressor protein class D | / | 0.449 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.449 | |
| 3s87 | ADP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.449 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.449 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.449 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.449 | |
| 3zgl | 10E | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | / | 0.449 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.449 | |
| 4f31 | KAI | Glutamate receptor 3 | / | 0.449 | |
| 4fse | 0VA | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.449 | |
| 4rww | 2BA | Lmo2692 protein | / | 0.449 | |
| 4y17 | LAE | Transcriptional regulator of ftsQAZ gene cluster | / | 0.449 | |
| 1a7x | FKA | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.448 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1icu | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.448 | |
| 1juv | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1q6y | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.448 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1t4c | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.448 | |
| 1ulb | GUN | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 1ykg | FMN | Sulfite reductase [NADPH] flavoprotein alpha-component | / | 0.448 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.448 | |
| 2dsg | SAH | Diphthine synthase | / | 0.448 | |
| 2e8h | SAH | Diphthine synthase | / | 0.448 | |
| 2fr1 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.448 | |
| 2gna | GDU | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.448 | |
| 2hl2 | SSA | Threonine--tRNA ligase | 6.1.1.3 | 0.448 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.448 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.448 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.448 | |
| 2zrx | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.448 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.448 | |
| 3kqb | LGJ | Coagulation factor X | 3.4.21.6 | 0.448 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.448 | |
| 3nks | ACJ | Protoporphyrinogen oxidase | 1.3.3.4 | 0.448 | |
| 3pft | FMN | Flavin reductase | / | 0.448 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.448 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.448 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 4d03 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.448 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4djw | 0KP | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4hyi | 1AO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.448 | |
| 4r1f | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.448 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.448 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.448 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.448 | |
| 4daj | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.448 | |
| 1ao8 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1e3l | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.447 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.447 | |
| 1je1 | GMP | Purine nucleoside phosphorylase | / | 0.447 | |
| 1k9s | FM1 | Purine nucleoside phosphorylase DeoD-type | / | 0.447 | |
| 1kfc | IPL | Tryptophan synthase alpha chain | / | 0.447 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.447 | |
| 1ri1 | GTG | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.447 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.447 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 2ibu | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.447 | |
| 2pch | SAH | Diphthine synthase | / | 0.447 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.447 | |
| 2uuo | LK3 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.447 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.447 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2y5g | FJD | Coagulation factor X | 3.4.21.6 | 0.447 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3hwx | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.447 | |
| 3hyg | 099 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.447 | |
| 3nd6 | ATP | Phosphopantetheine adenylyltransferase | / | 0.447 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.447 | |
| 3tb9 | CDP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.447 | |
| 3vjl | W94 | Dipeptidyl peptidase 4 | / | 0.447 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 4b05 | 32D | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.447 | |
| 4bqz | GNP | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.447 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.447 | |
| 4j0t | 6T9 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4na4 | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.447 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.447 | |
| 4um1 | 09P | Acetylcholine-binding protein | / | 0.447 | |
| 4ype | SAM | Histone-lysine N-methyltransferase ASH1L | 2.1.1.43 | 0.447 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.447 | |
| 3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.447 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.446 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.446 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.446 | |
| 1kbi | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.446 | |
| 1l2t | ATP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.446 | |
| 1lkd | BP6 | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.446 | |
| 1mmk | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.446 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.446 | |
| 1ws1 | BB2 | Peptide deformylase 1 | / | 0.446 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.446 | |
| 2d09 | FLV | Biflaviolin synthase CYP158A2 | / | 0.446 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.446 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.446 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.446 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.446 | |
| 2wf1 | ZY1 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 2ylx | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.446 | |
| 2zsi | GA4 | Gibberellin receptor GID1A | 3 | 0.446 | |
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 | / | 0.446 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.446 | |
| 3exo | 5MS | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.446 | |
| 3hbb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.446 | |
| 3kjm | 245 | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.446 | |
| 3lzx | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.446 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.446 | |
| 3pmu | F7L | Endothiapepsin | 3.4.23.22 | 0.446 | |
| 3uxv | GUN | NADPH-dependent 7-cyano-7-deazaguanine reductase | / | 0.446 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.446 | |
| 4a0r | DTB | Bifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial | 6.3.3.3 | 0.446 | |
| 4c0b | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.446 | |
| 4ef4 | C2E | Stimulator of interferon genes protein | / | 0.446 | |
| 4ehv | 0SJ | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 4jv3 | N32 | Beta-ketoacyl synthase | / | 0.446 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.446 | |
| 4l4x | NDP | AmphI | / | 0.446 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.446 | |
| 1a59 | COA | 2-methylcitrate synthase | / | 0.445 | |
| 1fkh | SBX | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.445 | |
| 1gtr | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.445 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.445 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 1ra8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1rd7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1t32 | OHH | Cathepsin G | 3.4.21.20 | 0.445 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.445 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.445 | |
| 2hp2 | KE4 | Glutamate-1-semialdehyde 2,1-aminomutase | 5.4.3.8 | 0.445 | |
| 2o7o | DXT | Tetracycline repressor protein class D | / | 0.445 | |
| 2xby | 63C | Coagulation factor X | 3.4.21.6 | 0.445 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2zrz | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.445 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.445 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.445 | |
| 3dt2 | GTP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.445 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.445 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.445 | |
| 3t6i | NC9 | Endothiapepsin | 3.4.23.22 | 0.445 | |
| 3u2m | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.445 | |
| 3udn | 09B | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4j0y | 1H6 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4j7g | TRH | PCZA361.3 | / | 0.445 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.445 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.444 | |
| 1f0x | FAD | D-lactate dehydrogenase | 1.1.1.28 | 0.444 | |
| 1jum | BER | HTH-type transcriptional regulator QacR | / | 0.444 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.444 | |
| 1pu9 | COA | HAT A1 | / | 0.444 | |
| 1q83 | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 1qvu | PRL | HTH-type transcriptional regulator QacR | / | 0.444 | |
| 1t3z | CAO | Formyl-CoA:oxalate CoA-transferase | / | 0.444 | |
| 2e83 | FMN | FMN-binding protein | / | 0.444 | |
| 2f99 | AKV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.444 | |
| 2fbw | CBE | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | 1.3.5.1 | 0.444 | |
| 2fbw | CBE | Succinate dehydrogenase cytochrome b, large subunit | / | 0.444 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.444 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.444 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.444 | |
| 2xj2 | 985 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
| 2yim | MC4 | Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase ) | / | 0.444 | |
| 3dsz | LIZ | Neutrophil gelatinase-associated lipocalin | / | 0.444 | |
| 3fpz | AHZ | Thiamine thiazole synthase | / | 0.444 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.444 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 3pd3 | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.444 | |
| 3t2v | KKJ | Peptidoglycan recognition protein 1 | / | 0.444 | |
| 3thy | ADP | DNA mismatch repair protein Msh2 | / | 0.444 | |
| 4a61 | ANP | Plasmid segregation protein ParM | / | 0.444 | |
| 4e2b | FMN | Dehydrogenase | / | 0.444 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.444 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.444 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.444 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.444 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.444 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.444 | |
| 1csc | CMC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.443 | |
| 1gvr | TNL | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 1ja0 | FAD | NADPH--cytochrome P450 reductase | / | 0.443 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.443 | |
| 1jom | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1lcz | BH7 | Streptavidin | / | 0.443 | |
| 1pwu | GM6 | Lethal factor | 3.4.24.83 | 0.443 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1vg8 | GNP | Ras-related protein Rab-7a | / | 0.443 | |
| 2b3d | FAD | Modulator of drug activity B | / | 0.443 | |
| 2hux | SAH | Diphthine synthase | / | 0.443 | |
| 2ibz | UQ6 | Cytochrome b | / | 0.443 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.443 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.443 | |
| 2vq7 | NAP | Putative flavin-containing monooxygenase | / | 0.443 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2xw1 | 9NV | Serum albumin | / | 0.443 | |
| 3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.443 | |
| 3ccb | B2Y | Dipeptidyl peptidase 4 | / | 0.443 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.443 | |
| 3iqg | ASN_TRP_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.443 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.443 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.443 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.443 | |
| 3ms5 | REE | Gamma-butyrobetaine dioxygenase | 1.14.11.1 | 0.443 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.443 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.443 | |
| 3r1r | ATP | Ribonucleoside-diphosphate reductase 1 subunit alpha | 1.17.4.1 | 0.443 | |
| 3vuc | HHE | Renin | 3.4.23.15 | 0.443 | |
| 3vye | VYE | Renin | 3.4.23.15 | 0.443 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 4b1h | AR6 | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.443 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4ise | 1FW | Glucokinase | 2.7.1.2 | 0.443 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.443 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.443 | |
| 4rel | KMP | Glycosyltransferase | / | 0.443 | |
| 4xqc | NAD | Homospermidine synthase | 2.5.1.44 | 0.443 | |
| 4yqf | GDP | Septin-9 | / | 0.443 | |
| 5fsi | 8DG | 7,8-dihydro-8-oxoguanine triphosphatase | 3.6.1.55 | 0.443 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.443 | |
| 5hg0 | SAM | Pantothenate synthetase | / | 0.443 | |
| 1cq7 | PY5 | Aspartate aminotransferase | 2.6.1.1 | 0.442 | |
| 1fls | WAY | Collagenase 3 | 3.4.24 | 0.442 | |
| 1ftl | DNQ | Glutamate receptor 2 | / | 0.442 | |
| 1gve | NAP | Aflatoxin B1 aldehyde reductase member 3 | 1 | 0.442 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1rfu | PLP | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
| 1x27 | ASP_TYR_VAL_HIS_PTR | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.442 | |
| 1zny | GDP | Guanylate kinase | 2.7.4.8 | 0.442 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.442 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.442 | |
| 2bri | ANP | Uridylate kinase | 2.7.4.22 | 0.442 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.442 | |
| 2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.442 | |
| 2dxx | SAH | Diphthine synthase | / | 0.442 | |
| 2e8r | SAH | Diphthine synthase | / | 0.442 | |
| 2ibw | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.442 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.442 | |
| 2wat | COA | Fatty acid synthase subunit alpha | 2.3.1.86 | 0.442 | |
| 2x2r | X2O | Kinesin-like protein KIF11 | / | 0.442 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.442 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.442 | |
| 3ens | ENS | Coagulation factor X | 3.4.21.6 | 0.442 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.442 | |
| 3f8s | PF2 | Dipeptidyl peptidase 4 | / | 0.442 | |
| 3fpk | FAD | Ferredoxin-NADP reductase | / | 0.442 | |
| 3k5f | AYH | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.442 | |
| 3u9y | 09L | Tankyrase-2 | 2.4.2.30 | 0.442 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.442 | |
| 4b1c | 1B1 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4bqh | 9VU | UDP-N-acetylglucosamine pyrophosphorylase, putative | / | 0.442 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.442 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.442 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.442 | |
| 4drn | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.442 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.442 | |
| 4qnw | FMN | Chanoclavine-I aldehyde reductase easA | / | 0.442 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.442 | |
| 4yfy | 1YJ | VioF | / | 0.442 | |
| 1bof | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.441 | |
| 1dyi | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1fdr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.441 | |
| 1fkj | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.441 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.441 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1umc | TDP | 2-oxoisovalerate dehydrogenase subunit alpha | 1.2.4.4 | 0.441 | |
| 1umc | TDP | 2-oxoisovalerate dehydrogenase subunit beta | 1.2.4.4 | 0.441 | |
| 2a2d | ANP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.441 | |
| 2ag1 | TPP | Benzaldehyde lyase | / | 0.441 | |
| 2bi4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.441 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.441 | |
| 2iml | FMN | Uncharacterized protein | / | 0.441 | |
| 2q7l | TES | Androgen receptor | / | 0.441 | |
| 2vd4 | P21 | Bifunctional protein GlmU | / | 0.441 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.441 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 3cxw | 7CP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 3f10 | 8HG | 8-oxoguanine-DNA-glycosylase | / | 0.441 | |
| 3fvq | ATP | Fe(3+) ions import ATP-binding protein FbpC | / | 0.441 | |
| 3hgr | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.441 | |
| 3hl4 | CDC | Choline-phosphate cytidylyltransferase A | / | 0.441 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.441 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.441 | |
| 3wb4 | 0B3 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4cjr | FYM | Integrase | / | 0.441 | |
| 4dro | 0MD | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.441 | |
| 4flj | Y08 | Methionine aminopeptidase 1 | / | 0.441 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.441 | |
| 4hr2 | ADP | Nucleoside diphosphate kinase | / | 0.441 | |
| 4j75 | TYM | Tryptophan--tRNA ligase | / | 0.441 | |
| 4jt9 | 1NS | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.441 | |
| 4k6m | SAH | Genome polyprotein | / | 0.441 | |
| 4koa | NDP | 1,5-anhydro-D-fructose reductase | 1.1.1.292 | 0.441 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.441 | |
| 4kx6 | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.441 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.441 | |
| 4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.441 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.441 | |
| 1f5n | GNP | Guanylate-binding protein 1 | / | 0.440 | |
| 1fkf | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.440 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.440 | |
| 1j37 | X8Z | Angiotensin-converting enzyme | 3.4.15.1 | 0.440 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.440 | |
| 1s20 | NAD | 2,3-diketo-L-gulonate reductase | 1.1.1.130 | 0.440 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.440 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.440 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.440 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.440 | |
| 2f6r | ACO | Bifunctional coenzyme A synthase | / | 0.440 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.440 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 2tys | PLT | Tryptophan synthase beta chain | 4.2.1.20 | 0.440 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.440 | |
| 3dgq | EAA | Glutathione S-transferase P | 2.5.1.18 | 0.440 | |
| 3h0w | N8M | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.440 | |
| 3hnz | PMN | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.440 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.440 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.440 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.440 | |
| 4du6 | GTP | GTP cyclohydrolase 1 | / | 0.440 | |
| 4eox | 0S5 | Peptide deformylase | / | 0.440 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 4m2b | UPG | UDP-glucose pyrophosphorylase | / | 0.440 | |
| 4o25 | GTP | GTP-binding protein Rheb | / | 0.440 | |
| 4plp | NAD | Homospermidine synthase | 2.5.1.44 | 0.440 | |
| 4rrg | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.440 | |
| 4u15 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.440 |