sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1px0 | RPN | Halohydrin dehalogenase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1px0 | RPN | Halohydrin dehalogenase | / | 1.000 | |
| 1zmt | RNO | Halohydrin dehalogenase | / | 0.642 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.539 | |
| 4bjb | P34 | Tankyrase-2 | 2.4.2.30 | 0.536 | |
| 1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.527 | |
| 4jqa | ID8 | Aldo-keto reductase family 1 member C2 | / | 0.526 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.524 | |
| 4m48 | 21B | Sodium-dependent dopamine transporter | / | 0.523 | |
| 2rds | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.521 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.520 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.519 | |
| 4gab | FID | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.516 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.513 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.512 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.511 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.511 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.509 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.509 | |
| 3bur | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.509 | |
| 4li6 | 1XO | Tankyrase-1 | 2.4.2.30 | 0.509 | |
| 2a3b | CFF | Endochitinase B1 | 3.2.1.14 | 0.508 | |
| 3l3l | L3L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.504 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.503 | |
| 4jtq | FLP | Aldo-keto reductase family 1 member C2 | / | 0.502 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.501 | |
| 1pj6 | FOL | Dimethylglycine oxidase | 1.5.3.10 | 0.501 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.501 | |
| 2wgs | 1AZ | Glutamine synthetase | 6.3.1.2 | 0.501 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.500 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.500 | |
| 1rvv | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.499 | |
| 3c72 | CX1 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.499 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.499 | |
| 2pnu | ENM | Androgen receptor | / | 0.497 | |
| 4hcy | 0YN | Transketolase | / | 0.497 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.496 | |
| 1s36 | CEI | Obelin | / | 0.496 | |
| 5ab6 | CAA | Nonspecific lipid-transfer protein, putative | / | 0.496 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.496 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.495 | |
| 2f0y | 3MN | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.495 | |
| 3dz6 | M8E | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.495 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.495 | |
| 4ixt | 1H1 | Halohydrin dehalogenase | / | 0.495 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.495 | |
| 1g3m | PCQ | Estrogen sulfotransferase | 2.8.2.4 | 0.494 | |
| 3hxc | BD6 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.494 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.494 | |
| 3rvi | RVI | Beta-secretase 1 | 3.4.23.46 | 0.494 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.493 | |
| 3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.493 | |
| 4tjy | 3GN | Tankyrase-2 | 2.4.2.30 | 0.493 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.492 | |
| 1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.492 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.492 | |
| 2ok7 | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.492 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.492 | |
| 4jq1 | NPS | Aldo-keto reductase family 1 member C2 | / | 0.492 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.491 | |
| 1z4i | UMP | 5'(3')-deoxyribonucleotidase, mitochondrial | 3.1.3 | 0.491 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.491 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.491 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.491 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.490 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.490 | |
| 1kf6 | HQO | Fumarate reductase iron-sulfur subunit | 1.3.5.1 | 0.489 | |
| 1kf6 | HQO | Fumarate reductase subunit C | / | 0.489 | |
| 1kf6 | HQO | Fumarate reductase subunit D | / | 0.489 | |
| 1kmv | LII | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
| 2j7c | IDE | Beta-glucosidase A | 3.2.1.21 | 0.489 | |
| 3gyf | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.489 | |
| 4e2y | JHZ | Methyltransferase | / | 0.489 | |
| 4jtr | IZP | Aldo-keto reductase family 1 member C2 | / | 0.489 | |
| 4u15 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.489 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.488 | |
| 1rkw | PNT | HTH-type transcriptional regulator QacR | / | 0.488 | |
| 3cas | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.488 | |
| 3tfj | THG | Dimethylsulfonioproprionate demethylase DmdA | 2.1.1.269 | 0.488 | |
| 4b68 | FAD | L-ornithine N(5)-monooxygenase | / | 0.488 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.487 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.487 | |
| 2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.487 | |
| 3iu9 | T07 | Methionine aminopeptidase 2 | / | 0.487 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.486 | |
| 3ksl | SZH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.486 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.486 | |
| 4cth | RDF | Neprilysin | / | 0.486 | |
| 1iei | ZES | Aldose reductase | 1.1.1.21 | 0.485 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.485 | |
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.485 | |
| 3nhp | HGZ | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.485 | |
| 3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.485 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.485 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.485 | |
| 4l32 | 1VF | Tankyrase-2 | 2.4.2.30 | 0.485 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.484 | |
| 1zua | TOL | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.484 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.484 | |
| 3pz2 | 3PZ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.484 | |
| 3pz4 | 3PZ | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.484 | |
| 4wcx | SAM | Biotin and thiamin synthesis associated | / | 0.484 | |
| 4gbr | CAU | Beta-2 adrenergic receptor | / | 0.484 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.483 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.483 | |
| 3ghw | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.483 | |
| 3p0e | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.483 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.483 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.483 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.483 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.482 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.482 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.482 | |
| 4gtt | 7TQ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.482 | |
| 4kn0 | MTX | Folate receptor beta | / | 0.482 | |
| 4nv1 | 4TG | Formyl transferase | / | 0.482 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.481 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.481 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.481 | |
| 2qcx | PF1 | Aminopyrimidine aminohydrolase | / | 0.481 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.481 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.481 | |
| 4gi4 | 0EX | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.481 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.481 | |
| 1v08 | NTZ | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.480 | |
| 2zsd | COA | Pantothenate kinase | 2.7.1.33 | 0.480 | |
| 3gki | CLR | Niemann-Pick C1 protein | / | 0.480 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.480 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.480 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.480 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.480 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.480 | |
| 1aiq | CB3 | Thymidylate synthase | / | 0.479 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.479 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.479 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.479 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.479 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.479 | |
| 2vt4 | P32 | Beta-1 adrenergic receptor | / | 0.479 | |
| 3ghs | LDT | Aldose reductase | 1.1.1.21 | 0.479 | |
| 3r8h | ZOM | Aldo-keto reductase family 1 member C3 | / | 0.479 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.479 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.478 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.478 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.478 | |
| 3bjc | WAN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.478 | |
| 3l9m | L9M | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.478 | |
| 3lm4 | HPX | Catechol 2,3-dioxygenase | / | 0.478 | |
| 3p2v | DOY | Aldose reductase | 1.1.1.21 | 0.478 | |
| 4e2z | JHZ | Methyltransferase | / | 0.478 | |
| 4g8b | HL6 | Alpha/beta hydrolase fold protein | / | 0.478 | |
| 4gtv | 7TR | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.478 | |
| 4h6z | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.478 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.477 | |
| 1sre | HAB | Streptavidin | / | 0.477 | |
| 1swn | BTN | Streptavidin | / | 0.477 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.477 | |
| 2brt | NAR | Leucoanthocyanidin dioxygenase | 1.14.11.19 | 0.477 | |
| 2cbq | TH2 | Neocarzinostatin | / | 0.477 | |
| 2d06 | EST | Sulfotransferase 1A1 | 2.8.2.1 | 0.477 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.477 | |
| 2uuj | 896 | Prothrombin | 3.4.21.5 | 0.477 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.477 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.477 | |
| 3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.477 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.477 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.477 | |
| 4hkn | LU2 | Tankyrase-2 | 2.4.2.30 | 0.477 | |
| 4jq3 | ZOM | Aldo-keto reductase family 1 member C2 | / | 0.477 | |
| 1i7c | MGB | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.476 | |
| 1ni1 | 2C5 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.476 | |
| 2ejz | SAH | Diphthine synthase | / | 0.476 | |
| 2vdm | AGG | Integrin alpha-IIb | / | 0.476 | |
| 2vdm | AGG | Integrin beta-3 | / | 0.476 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.476 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.476 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.476 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.476 | |
| 5agy | GTB | Tau class glutathione S-transferase | / | 0.476 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.475 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.475 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.475 | |
| 3zno | SE5 | D-amino-acid oxidase | 1.4.3.3 | 0.475 | |
| 4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.475 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.474 | |
| 1pj7 | FFO | Dimethylglycine oxidase | 1.5.3.10 | 0.474 | |
| 1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.474 | |
| 2cul | FAD | GidA-related protein | / | 0.474 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.474 | |
| 2rd6 | 78P | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.474 | |
| 2vqo | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.474 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.474 | |
| 3arv | SAU | Chitinase A | / | 0.474 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.474 | |
| 3gsi | THG | Dimethylglycine oxidase | 1.5.3.10 | 0.474 | |
| 3hxf | BD9 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.474 | |
| 3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.474 | |
| 3p9t | TCL | Repressor | / | 0.474 | |
| 4kxj | P34 | Nucleoprotein | / | 0.474 | |
| 4x9d | U5P | Uncharacterized protein MJ1435 | / | 0.474 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 1u70 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.473 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 3c1o | NAP | Eugenol synthase | / | 0.473 | |
| 4b66 | FAD | L-ornithine N(5)-monooxygenase | / | 0.473 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.473 | |
| 3uon | QNB | Muscarinic acetylcholine receptor M2 | / | 0.473 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.472 | |
| 1hp0 | AD3 | IAG-nucleoside hydrolase | / | 0.472 | |
| 1lke | DOG | Bilin-binding protein | / | 0.472 | |
| 1ohj | COP | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.472 | |
| 2aj4 | ANP | Galactokinase | 2.7.1.6 | 0.472 | |
| 2dv0 | ZST | Aldose reductase | 1.1.1.21 | 0.472 | |
| 2fz8 | ZST | Aldose reductase | 1.1.1.21 | 0.472 | |
| 3b82 | NAD | Exotoxin A | 2.4.2.36 | 0.472 | |
| 3cui | X4S | Exoglucanase/xylanase | 3.2.1.91 | 0.472 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.472 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.472 | |
| 4fev | PP1 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.472 | |
| 1lce | TMF | Thymidylate synthase | / | 0.471 | |
| 1ni1 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.471 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.471 | |
| 2vqj | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.471 | |
| 2vqq | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.471 | |
| 2xnv | VU3 | Soluble acetylcholine receptor | / | 0.471 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.471 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.471 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.471 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.471 | |
| 3uyk | 0CX | Probable NDP-rhamnosyltransferase | / | 0.471 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.471 | |
| 4jq2 | SUZ | Aldo-keto reductase family 1 member C2 | / | 0.471 | |
| 4kn1 | 04J | Folate receptor beta | / | 0.471 | |
| 1ah3 | TOL | Aldose reductase | 1.1.1.21 | 0.470 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.470 | |
| 1z89 | 62P | Aldose reductase | 1.1.1.21 | 0.470 | |
| 1zos | MTM | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | / | 0.470 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.470 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.470 | |
| 2fzd | TOL | Aldose reductase | 1.1.1.21 | 0.470 | |
| 2xej | OKD | Glutamate carboxypeptidase 2 | 3.4.17.21 | 0.470 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.470 | |
| 3nyt | ULP | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.470 | |
| 3pz3 | PZ3 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.470 | |
| 3rqm | X2E | Nitric oxide synthase, brain | 1.14.13.39 | 0.470 | |
| 4a4x | JUP | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.470 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.470 | |
| 4dbu | BT9 | Aldo-keto reductase family 1 member C3 | / | 0.470 | |
| 1dls | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.469 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.469 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.469 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.469 | |
| 2pd9 | FID | Aldose reductase | 1.1.1.21 | 0.469 | |
| 2q3e | UPG | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.469 | |
| 3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.469 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.469 | |
| 4a16 | H34 | Acetylcholinesterase | 3.1.1.7 | 0.469 | |
| 4g34 | 924 | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.469 | |
| 4hmn | 16J | Aldo-keto reductase family 1 member C3 | / | 0.469 | |
| 4ia0 | 5BB | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.469 | |
| 1eko | I84 | Aldose reductase | 1.1.1.21 | 0.468 | |
| 1o6r | R19 | Squalene--hopene cyclase | 4.2.1.129 | 0.468 | |
| 1w19 | T4P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.468 | |
| 2psj | CEI | Renilla-luciferin 2-monooxygenase | 1.13.12.5 | 0.468 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.468 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.468 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.468 | |
| 4a39 | GEM | Uncharacterized protein | / | 0.468 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 4k37 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.468 | |
| 4lut | DCS | Alanine racemase | / | 0.468 | |
| 4xt8 | TMQ | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.468 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.468 | |
| 1ef3 | FID | Aldose reductase | 1.1.1.21 | 0.467 | |
| 1nc1 | MTH | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | 3.2.2.9 | 0.467 | |
| 2g7y | MO9 | Cathepsin S | 3.4.22.27 | 0.467 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 2pdn | 47D | Aldose reductase | 1.1.1.21 | 0.467 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.467 | |
| 3hxb | BD5 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.467 | |
| 3ntz | 3TZ | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.467 | |
| 3t0k | DCQ | Sulfide-quinone reductase | / | 0.467 | |
| 4iae | 1DX | Alr2278 protein | / | 0.467 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.467 | |
| 1e1f | PSG | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.466 | |
| 1nen | DNT | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.466 | |
| 1nen | DNT | Succinate dehydrogenase cytochrome b556 subunit | / | 0.466 | |
| 1pd8 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.466 | |
| 1srf | MTB | Streptavidin | / | 0.466 | |
| 1uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.466 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.466 | |
| 2pdx | ZST | Aldose reductase | 1.1.1.21 | 0.466 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.466 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.466 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.466 | |
| 3ghr | LDT | Aldose reductase | 1.1.1.21 | 0.466 | |
| 3ntq | NAD | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.466 | |
| 3o73 | O73 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.466 | |
| 4bfs | ZVS | Pantothenate kinase | 2.7.1.33 | 0.466 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.466 | |
| 4e32 | DWN | Methyltransferase | / | 0.466 | |
| 4m6k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.465 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.465 | |
| 2aou | CQA | Histamine N-methyltransferase | 2.1.1.8 | 0.465 | |
| 2q94 | A04 | Methionine aminopeptidase | / | 0.465 | |
| 3zpq | XF5 | Beta-1 adrenergic receptor | / | 0.465 | |
| 4kmz | FOL | Folate receptor beta | / | 0.465 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.465 | |
| 5ab7 | MLC | Nonspecific lipid-transfer protein, putative | / | 0.465 | |
| 1hfr | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1lel | BH7 | Avidin | / | 0.464 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.464 | |
| 1srj | NAB | Streptavidin | / | 0.464 | |
| 1wop | FFO | Aminomethyltransferase | / | 0.464 | |
| 1zdw | FLV | Prenyltransferase | / | 0.464 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.464 | |
| 2xq0 | BES | Leukotriene A-4 hydrolase homolog | 3.3.2.6 | 0.464 | |
| 2xys | SY9 | Soluble acetylcholine receptor | / | 0.464 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.464 | |
| 2zsc | BTN | Tamavidin2 | / | 0.464 | |
| 3c36 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.464 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.464 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 3h0v | M2T | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.464 | |
| 3pah | XDE | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.464 | |
| 3t42 | 3T4 | Aldose reductase | 1.1.1.21 | 0.464 | |
| 3uwe | VJJ | Aldo-keto reductase family 1 member C3 | / | 0.464 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.464 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.464 | |
| 4bus | 32F | Tankyrase-2 | 2.4.2.30 | 0.464 | |
| 4bvn | P32 | Beta-1 adrenergic receptor | / | 0.464 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.464 | |
| 4hlm | 16S | Tankyrase-2 | 2.4.2.30 | 0.464 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.464 | |
| 4mry | CEI | Obelin | / | 0.464 | |
| 4phl | PIL | Phosphodiesterase | / | 0.464 | |
| 4xp4 | COC | Sodium-dependent dopamine transporter | / | 0.464 | |
| 5cxv | 0HK | Muscarinic acetylcholine receptor M1 | / | 0.464 | |
| 1cbr | REA | Cellular retinoic acid-binding protein 1 | / | 0.463 | |
| 1ddt | APU | Diphtheria toxin | / | 0.463 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.463 | |
| 1oz0 | MS1 | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.463 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.463 | |
| 1x8b | 824 | Wee1-like protein kinase | 2.7.10.2 | 0.463 | |
| 1y52 | BTN | Avidin-related protein 4/5 | / | 0.463 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.463 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.463 | |
| 2uup | LK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.463 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.463 | |
| 2zgx | 29U | Prothrombin | 3.4.21.5 | 0.463 | |
| 3ndj | JHZ | Methyltransferase | / | 0.463 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.463 | |
| 3wtk | TH4 | Acetylcholine-binding protein | / | 0.463 | |
| 4cx5 | HW8 | Nitric oxide synthase, brain | 1.14.13.39 | 0.463 | |
| 4gtm | 7TM | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.463 | |
| 4n1g | CEI | Obelin | / | 0.463 | |
| 4pnr | G18 | Tankyrase-2 | 2.4.2.30 | 0.463 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.463 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.463 | |
| 2y04 | 68H | Beta-1 adrenergic receptor | / | 0.463 | |
| 1c4y | IH3 | Prothrombin | 3.4.21.5 | 0.462 | |
| 1g8o | U5P | N-acetyllactosaminide alpha-1,3-galactosyltransferase | / | 0.462 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.462 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 1qip | GNB | Lactoylglutathione lyase | 4.4.1.5 | 0.462 | |
| 1re0 | AFB | ADP-ribosylation factor 1 | / | 0.462 | |
| 1re0 | AFB | ARF guanine-nucleotide exchange factor 1 | / | 0.462 | |
| 1rxh | BNI | Streptavidin | / | 0.462 | |
| 1s63 | 778 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.462 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 2aot | 2PM | Histamine N-methyltransferase | 2.1.1.8 | 0.462 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.462 | |
| 2pdl | TOL | Aldose reductase | 1.1.1.21 | 0.462 | |
| 2v9c | MRE | FMN-dependent NADH-azoreductase 1 | / | 0.462 | |
| 2wjo | QUD | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 2y6d | TQJ | Matrilysin | 3.4.24.23 | 0.462 | |
| 2zg0 | 50U | Prothrombin | 3.4.21.5 | 0.462 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.462 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.462 | |
| 3u5y | SCG | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.462 | |
| 3zec | ANP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.462 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.462 | |
| 4bup | SAM | Histone-lysine N-methyltransferase KMT5B | 2.1.1.43 | 0.462 | |
| 4itx | IN5 | Cystathionine beta-lyase MetC | 4.4.1.8 | 0.462 | |
| 4jhi | EMU | Nodulin-13 | / | 0.462 | |
| 5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.462 | |
| 3ny8 | JRZ | Beta-2 adrenergic receptor | / | 0.462 | |
| 3ny9 | JSZ | Beta-2 adrenergic receptor | / | 0.462 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.461 | |
| 1odn | APV | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 1rxj | BNI | Streptavidin | / | 0.461 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.461 | |
| 1yho | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.461 | |
| 2bn4 | FAD | NADPH--cytochrome P450 reductase | / | 0.461 | |
| 2pdu | 393 | Aldose reductase | 1.1.1.21 | 0.461 | |
| 2vrj | NCW | Beta-glucosidase A | 3.2.1.21 | 0.461 | |
| 3b8x | G4M | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.461 | |
| 3pg3 | DG7 | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 3rth | RTH | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.461 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.461 | |
| 4g8c | C6L | Alpha/beta hydrolase fold protein | / | 0.461 | |
| 4glx | 0XS | DNA ligase | 6.5.1.2 | 0.461 | |
| 1jf2 | CZH | Obelin | / | 0.460 | |
| 1r8q | AFB | Cytohesin-2 | / | 0.460 | |
| 1r8q | AFB | ADP-ribosylation factor 1 | / | 0.460 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.460 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.460 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.460 | |
| 2ipi | AKY | Aclacinomycin-N/aclacinomycin-A oxidase | / | 0.460 | |
| 2oli | IOP | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.460 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.460 | |
| 3d4b | DZD | NAD-dependent protein deacetylase | / | 0.460 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.460 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 3rl4 | 5GP | Metallophosphoesterase MPPED2 | 3.1 | 0.460 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.460 | |
| 3w4k | 3LD | D-amino-acid oxidase | 1.4.3.3 | 0.460 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.460 | |
| 4b67 | NAP | L-ornithine N(5)-monooxygenase | / | 0.460 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.460 | |
| 4lcn | GNG | Cytidine and deoxycytidylate deaminase zinc-binding region | / | 0.460 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.460 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1uhj | CZB | Aequorin-2 | / | 0.459 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.459 | |
| 1z3n | 3NA | Aldose reductase | 1.1.1.21 | 0.459 | |
| 2aov | C2M | Histamine N-methyltransferase | 2.1.1.8 | 0.459 | |
| 2cf9 | 348 | Prothrombin | 3.4.21.5 | 0.459 | |
| 2ckm | AA7 | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 2fzb | TOL | Aldose reductase | 1.1.1.21 | 0.459 | |
| 2q93 | B21 | Methionine aminopeptidase | / | 0.459 | |
| 2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.459 | |
| 2yhu | WHF | Pteridine reductase | / | 0.459 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.459 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.459 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.459 | |
| 3gn7 | 3GN | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.459 | |
| 3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.459 | |
| 3r6i | JMS | Aldo-keto reductase family 1 member C3 | / | 0.459 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.459 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.459 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.459 | |
| 4j22 | AJ7 | Tankyrase-2 | 2.4.2.30 | 0.459 | |
| 4l4v | 1VY | Major histocompatibility complex class I-related gene protein | / | 0.459 | |
| 4lb2 | DM5 | Serum albumin | / | 0.459 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.458 | |
| 1dpm | EBP | Parathion hydrolase | 3.1.8.1 | 0.458 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.458 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.458 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.458 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.458 | |
| 1ycf | FMN | Nitric oxide reductase | 1 | 0.458 | |
| 2fz9 | ZST | Aldose reductase | 1.1.1.21 | 0.458 | |
| 2iki | 388 | Aldose reductase | 1.1.1.21 | 0.458 | |
| 2p98 | YE7 | Methionine aminopeptidase | / | 0.458 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.458 | |
| 2xlp | NAP | Putative flavin-containing monooxygenase | / | 0.458 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.458 | |
| 3e4a | QIX | Insulin-degrading enzyme | 3.4.24.56 | 0.458 | |
| 3fu8 | 3DM | Laccase-1 | 1.10.3.2 | 0.458 | |
| 3lfz | ADP | Uncharacterized protein MJ1225 | / | 0.458 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.458 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.458 | |
| 3w6u | NAP | 6-phosphogluconate dehydrogenase, NAD-binding protein | / | 0.458 | |
| 3wi2 | P98 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.458 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 4d03 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.458 | |
| 4ggz | BTN | Bll1558 protein | / | 0.458 | |
| 4gkh | 0J9 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.458 | |
| 4jt9 | 1NS | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.458 | |
| 4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.458 | |
| 4m0c | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.458 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.458 | |
| 4rxr | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.458 | |
| 5ark | UMP | Ribonuclease 4 | 3.1.27 | 0.458 | |
| 2ycx | P32 | Beta-1 adrenergic receptor | / | 0.458 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 1kwc | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.457 | |
| 1ndy | FR3 | Adenosine deaminase | 3.5.4.4 | 0.457 | |
| 1vrq | FON | Subunit alpha of sarocosine oxidase | / | 0.457 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.457 | |
| 1xnz | FCD | Methionine aminopeptidase | / | 0.457 | |
| 1xzq | FON | tRNA modification GTPase MnmE | 3.6.5 | 0.457 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
| 2cn0 | F25 | Prothrombin | 3.4.21.5 | 0.457 | |
| 2iej | S48 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.457 | |
| 2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.457 | |
| 2pdw | FID | Aldose reductase | 1.1.1.21 | 0.457 | |
| 2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 2zdv | 37U | Prothrombin | 3.4.21.5 | 0.457 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.457 | |
| 3f6r | FMN | Flavodoxin | / | 0.457 | |
| 3ry2 | BTN | Streptavidin | / | 0.457 | |
| 3v35 | NTI | Aldose reductase | 1.1.1.21 | 0.457 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.457 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 4drh | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.457 | |
| 4drh | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.457 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.457 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.457 | |
| 4l0t | 1V0 | Tankyrase-2 | 2.4.2.30 | 0.457 | |
| 4wbd | ADP | Putative cysteine ligase BshC | / | 0.457 | |
| 4xo7 | ASD | Aldo-keto reductase family 1 member C2 | / | 0.457 | |
| 4y1b | NAP | AntE | / | 0.457 | |
| 5ees | NAP | 4-hydroxy-tetrahydrodipicolinate reductase | / | 0.457 | |
| 1jf0 | CZH | Obelin | / | 0.456 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.456 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.456 | |
| 1vzq | SHY | Prothrombin | 3.4.21.5 | 0.456 | |
| 1y6r | MTM | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | 3.2.2.9 | 0.456 | |
| 2cmf | F11 | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 2iu8 | UD1 | UDP-3-O-acylglucosamine N-acyltransferase | 2.3.1 | 0.456 | |
| 2j83 | BAT | Ulilysin | 3.4.24 | 0.456 | |
| 2q15 | 3MR | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 2zu9 | GDP | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.456 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.456 | |
| 3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.456 | |
| 3klb | FMN | Uncharacterized protein | / | 0.456 | |
| 3pn1 | IVH | DNA ligase | / | 0.456 | |
| 3ug8 | IMN | Aldo-keto reductase family 1 member C3 | / | 0.456 | |
| 4ddr | MMV | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 4n82 | FMN | Ribonucleotide reductase (NrdI family protein), putative | / | 0.456 | |
| 4pab | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.456 | |
| 4yfy | 0FX | VioF | / | 0.456 | |
| 5a4v | QUE | Glutathione S-transferase F2 | 2.5.1.18 | 0.456 | |
| 5ds3 | 09L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.456 | |
| 5a8e | XTK | Beta-1 adrenergic receptor | / | 0.456 | |
| 1pax | DHQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.455 | |
| 1pwl | BFI | Aldose reductase | 1.1.1.21 | 0.455 | |
| 1w76 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 1yci | NDF | Hypoxia-inducible factor 1-alpha inhibitor | 1.14.11.30 | 0.455 | |
| 2fl2 | ADP | Kinesin-like protein KIF11 | / | 0.455 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 2hz4 | 4ST | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.455 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.455 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 3l3m | A92 | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.455 | |
| 3rl3 | 5GP | Metallophosphoesterase MPPED2 | 3.1 | 0.455 | |
| 4c2z | 646 | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.455 | |
| 4ixc | 1JD | Glucokinase | 2.7.1.2 | 0.455 | |
| 2ycz | I32 | Beta-1 adrenergic receptor | / | 0.455 | |
| 1axw | MTX | Thymidylate synthase | / | 0.454 | |
| 1gp6 | QUE | Leucoanthocyanidin dioxygenase | 1.14.11.19 | 0.454 | |
| 1isg | AGS | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 | 3.2.2.6 | 0.454 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.454 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.454 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.454 | |
| 1s64 | 778 | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.454 | |
| 1sjw | NGV | Nogalonic acid methyl ester cyclase | / | 0.454 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.454 | |
| 1xng | DND | NH(3)-dependent NAD(+) synthetase | 6.3.1.5 | 0.454 | |
| 1ypm | RA4 | Prothrombin | 3.4.21.5 | 0.454 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 2dux | ZST | Aldose reductase | 1.1.1.21 | 0.454 | |
| 2w4q | CBW | Prostaglandin reductase 2 | 1.3.1.48 | 0.454 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3hv3 | R49 | Mitogen-activated protein kinase 14 | / | 0.454 | |
| 3n19 | FNR | Xenobiotic reductase | / | 0.454 | |
| 3nxr | D2D | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3ptz | UDX | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.454 | |
| 3qvi | K95 | HAP protein | / | 0.454 | |
| 3sl8 | JN7 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 3x02 | 5GP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.454 | |
| 4at4 | T6E | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.454 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.454 | |
| 4jpg | 1OX | Pyruvate kinase PKM | 2.7.1.40 | 0.454 | |
| 4l2g | 1V4 | Tankyrase-2 | 2.4.2.30 | 0.454 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.454 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.454 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.454 | |
| 8cat | NDP | Catalase | 1.11.1.6 | 0.454 | |
| 1n9m | BTN | Streptavidin | / | 0.453 | |
| 1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.453 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.453 | |
| 2a2d | ANP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.453 | |
| 2a4x | BLM | Mitomycin-binding protein | / | 0.453 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.453 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3ftx | RE2 | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.453 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 3sfh | 1DI | Histone deacetylase 8 | 3.5.1.98 | 0.453 | |
| 3zj7 | C1K | Strictosidine-O-beta-D-glucosidase | 3.2.1.105 | 0.453 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 4bx7 | B4F | Streptavidin | / | 0.453 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
| 4kw5 | 1W6 | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.453 | |
| 4nqg | CZH | Mitrocomin | / | 0.453 | |
| 2ycy | P32 | Beta-1 adrenergic receptor | / | 0.453 | |
| 1afe | ALZ | Prothrombin | 3.4.21.5 | 0.452 | |
| 1al7 | HST | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.452 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 1ddu | DDU | Thymidylate synthase | / | 0.452 | |
| 1r5h | AO2 | Methionine aminopeptidase 2 | / | 0.452 | |
| 1w29 | TS1 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.452 | |
| 2b8j | ADN | Class B acid phosphatase | 3.1.3.2 | 0.452 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 2gpj | FAD | Siderophore-interacting protein | / | 0.452 | |
| 2iqd | LPA | Aldose reductase | 1.1.1.21 | 0.452 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.452 | |
| 2r86 | ATP | 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase | / | 0.452 | |
| 2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.452 | |
| 2vq7 | NAP | Putative flavin-containing monooxygenase | / | 0.452 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.452 | |
| 2ycw | CAU | Beta-1 adrenergic receptor | / | 0.452 | |
| 2z2w | 770 | Wee1-like protein kinase | 2.7.10.2 | 0.452 | |
| 3gg2 | UGA | Sugar dehydrogenase, UDP-glucose/GDP-mannose dehydrogenase family | / | 0.452 | |
| 3ix4 | TX1 | Transcriptional activator protein LasR | / | 0.452 | |
| 3kkz | SAM | Uncharacterized protein | / | 0.452 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 4hyf | 1AK | Tankyrase-2 | 2.4.2.30 | 0.452 | |
| 4kzu | A73 | Tankyrase-2 | 2.4.2.30 | 0.452 | |
| 4l34 | 1VG | Tankyrase-2 | 2.4.2.30 | 0.452 | |
| 4lsa | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.452 | |
| 4mle | VO1 | Glucokinase | 2.7.1.2 | 0.452 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.452 | |
| 5bt4 | 2LO | Bromodomain-containing protein 4 | / | 0.452 | |
| 5jhn | SAM | Histone-lysine N-methyltransferase EHMT2 | / | 0.452 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.452 | |
| 5jqh | CAU | Beta-2 adrenergic receptor | / | 0.452 | |
| 1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1el4 | CTZ | Obelin | / | 0.451 | |
| 1fml | RTL | Retinol dehydratase | / | 0.451 | |
| 1kw8 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.451 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.451 | |
| 1sg0 | STL | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.451 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.451 | |
| 1w1v | ALJ | Chitinase | / | 0.451 | |
| 2am2 | 2LG | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.451 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.451 | |
| 2hq9 | FAD | Mll6688 protein | / | 0.451 | |
| 2hv5 | ZST | Aldose reductase | 1.1.1.21 | 0.451 | |
| 2q92 | B23 | Methionine aminopeptidase | / | 0.451 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 3dej | RXC | Caspase-3 | 3.4.22.56 | 0.451 | |
| 3gey | P34 | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.451 | |
| 3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.451 | |
| 3qdz | PRO_ALA_PRO_ARG | Prothrombin | 3.4.21.5 | 0.451 | |
| 3r7m | SUZ | Aldo-keto reductase family 1 member C3 | / | 0.451 | |
| 3w3z | GTP | GTP-binding nuclear protein Ran | / | 0.451 | |
| 3wth | IM4 | Acetylcholine-binding protein | / | 0.451 | |
| 4bcs | BTN | Avidin-related protein 4/5 | / | 0.451 | |
| 4g1n | NZT | Pyruvate kinase PKM | 2.7.1.40 | 0.451 | |
| 4mz7 | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.451 | |
| 4n3r | 2GU | Tankyrase-1 | 2.4.2.30 | 0.451 | |
| 4nv1 | 0FX | Formyl transferase | / | 0.451 | |
| 4tvj | 09L | Poly [ADP-ribose] polymerase 2 | 2.4.2.30 | 0.451 | |
| 4wev | SUZ | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.451 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.451 | |
| 1frb | ZST | Aldose reductase-related protein 2 | / | 0.450 | |
| 1rkp | IBM | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.450 | |
| 1uhh | CZP | Aequorin-2 | / | 0.450 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.450 | |
| 1y6q | TDI | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | 3.2.2.9 | 0.450 | |
| 2in6 | 839 | Wee1-like protein kinase | 2.7.10.2 | 0.450 | |
| 2pdm | ZST | Aldose reductase | 1.1.1.21 | 0.450 | |
| 2rtf | BTN | Streptavidin | / | 0.450 | |
| 2wn6 | NDP | ADP-ribosyltransferase enzymatic component | / | 0.450 | |
| 2zoz | ET | Transcriptional regulator | / | 0.450 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 3dlc | SAM | SAM (And some other nucleotide) binding motif:Generic methyltransferase | / | 0.450 | |
| 3gam | MXX | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.450 | |
| 3h0w | N8M | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.450 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 3ld5 | LDT | Aldose reductase | 1.1.1.21 | 0.450 | |
| 3lm1 | LEC | Agglutinin alpha chain | / | 0.450 | |
| 3nhu | M42 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.450 | |
| 3p8h | P8H | Lethal(3)malignant brain tumor-like protein 1 | / | 0.450 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.450 | |
| 4bjc | RPB | Tankyrase-2 | 2.4.2.30 | 0.450 | |
| 4bmz | MTA | Aminodeoxyfutalosine nucleosidase | / | 0.450 | |
| 4bvh | OCZ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.450 | |
| 4c3y | ANB | 3-ketosteroid dehydrogenase | / | 0.450 | |
| 4c49 | HCY | Corticosteroid-binding globulin | / | 0.450 | |
| 4dm6 | TTB | Retinoic acid receptor beta | / | 0.450 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.450 | |
| 4gd9 | BTN | Streptavidin | / | 0.450 | |
| 4gtp | 7TP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.450 | |
| 4i10 | 1BS | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4kfj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4zvn | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.450 | |
| 1gm8 | SOX | Penicillin G acylase | 3.5.1.11 | 0.449 | |
| 1gp6 | DH2 | Leucoanthocyanidin dioxygenase | 1.14.11.19 | 0.449 | |
| 1o1t | 2NH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.449 | |
| 1pke | 2FD | Purine nucleoside phosphorylase DeoD-type | / | 0.449 | |
| 1v5y | 4HC | Major NAD(P)H-flavin oxidoreductase | 1.6.99 | 0.449 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 1ycg | FMN | Nitric oxide reductase | 1 | 0.449 | |
| 2bu5 | TF1 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.449 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2evm | FC2 | Methionine aminopeptidase | / | 0.449 | |
| 2ggb | U17 | Methionine aminopeptidase | / | 0.449 | |
| 2gl0 | ADN | Uncharacterized protein | / | 0.449 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.449 | |
| 2vuu | NAP | Nitrogen metabolite repression protein nmrA | / | 0.449 | |
| 2y02 | WHJ | Beta-1 adrenergic receptor | / | 0.449 | |
| 2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.449 | |
| 3fsj | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.449 | |
| 3fu9 | KIB | Laccase-1 | 1.10.3.2 | 0.449 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.449 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.449 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 3znq | SS8 | D-amino-acid oxidase | 1.4.3.3 | 0.449 | |
| 4dch | 4DC | Glucokinase | 2.7.1.2 | 0.449 | |
| 4dk7 | 0KS | Oxysterols receptor LXR-beta | / | 0.449 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.449 | |
| 4dri | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.449 | |
| 4dri | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.449 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 4j7h | TRH | PCZA361.3 | / | 0.449 | |
| 4lng | JAN | CaaX farnesyltransferase beta subunit Ram1 | / | 0.449 | |
| 4lrr | CF9 | Thymidylate synthase | / | 0.449 | |
| 5p2p | DHG | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.449 | |
| 1ae8 | AZL | Prothrombin | 3.4.21.5 | 0.448 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.448 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.448 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 1h69 | ARH | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1lkd | BP6 | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.448 | |
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.448 | |
| 1qsn | COA | HAT A1 | / | 0.448 | |
| 1sqi | 869 | 4-hydroxyphenylpyruvate dioxygenase | / | 0.448 | |
| 1t40 | ID5 | Aldose reductase | 1.1.1.21 | 0.448 | |
| 1ypg | UIR | Prothrombin | 3.4.21.5 | 0.448 | |
| 2qe2 | 452 | Polyprotein | / | 0.448 | |
| 2xkc | 4VQ | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.448 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.448 | |
| 3cgy | RDC | Virulence sensor histidine kinase PhoQ | 2.7.13.3 | 0.448 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 3e32 | ED2 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.448 | |
| 3hu2 | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.448 | |
| 3i7v | B4P | AP4A hydrolase | / | 0.448 | |
| 3k45 | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.448 | |
| 3l9l | L9L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 3s5w | FAD | L-ornithine N(5)-monooxygenase | / | 0.448 | |
| 4b05 | 32D | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4b2g | V1N | Uncharacterized protein | / | 0.448 | |
| 4b5n | FMN | NAD(P)H:flavin oxidoreductase Sye4 | / | 0.448 | |
| 4d6q | PD2 | Lysine-specific demethylase 4D | 1.14.11 | 0.448 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 4hb9 | FAD | Uncharacterized protein | / | 0.448 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.448 | |
| 4o9c | COA | Acetyl-CoA acetyltransferase | 2.3.1.9 | 0.448 | |
| 1ddu | CB3 | Thymidylate synthase | / | 0.447 | |
| 1dtp | APU | Diphtheria toxin | / | 0.447 | |
| 1eir | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.447 | |
| 1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.447 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.447 | |
| 1q23 | FUA | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.447 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1typ | NAP | Trypanothione reductase | 1.8.1.12 | 0.447 | |
| 1uk0 | FRM | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.447 | |
| 2i16 | LDT | Aldose reductase | 1.1.1.21 | 0.447 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.447 | |
| 2wmd | ZZ0 | NmrA-like family domain-containing protein 1 | / | 0.447 | |
| 3ai0 | PNW | Beta-glucosidase | / | 0.447 | |
| 3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.447 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.447 | |
| 3ce0 | P34 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.447 | |
| 3nhr | RZW | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.447 | |
| 3px2 | T3Q | dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase | 2.1.1.235 | 0.447 | |
| 3r8g | IZP | Aldo-keto reductase family 1 member C3 | / | 0.447 | |
| 4c77 | N01 | Phenylacetone monooxygenase | 1.14.13.92 | 0.447 | |
| 4dvq | 1CA | Cytochrome P450 11B2, mitochondrial | 1.14.15.4 | 0.447 | |
| 4eux | HW1 | Nitric oxide synthase, brain | 1.14.13.39 | 0.447 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.447 | |
| 4i5x | FLF | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.447 | |
| 4j1k | 1HG | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4l31 | F08 | Tankyrase-2 | 2.4.2.30 | 0.447 | |
| 5d6l | CAU | Beta-2 adrenergic receptor | / | 0.447 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.446 | |
| 1db5 | 6IN | Phospholipase A2, membrane associated | / | 0.446 | |
| 1gt5 | BZQ | Odorant-binding protein | / | 0.446 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.446 | |
| 1luq | BTN | Streptavidin | / | 0.446 | |
| 1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.446 | |
| 1qk3 | 5GP | Hypoxanthine-guanine-xanthine phosphoribosyltransferase | 2.4.2.22 | 0.446 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.446 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.446 | |
| 2oal | FAD | Flavin-dependent tryptophan halogenase RebH | 1.14.19.9 | 0.446 | |
| 2on6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 2ozr | GG1 | Collagenase 3 | 3.4.24 | 0.446 | |
| 2v34 | CTN | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.446 | |
| 2wea | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.446 | |
| 2zhw | 12U | Prothrombin | 3.4.21.5 | 0.446 | |
| 3akl | ADP | Serine/threonine-protein kinase CtkA | 2.7.11.1 | 0.446 | |
| 3dz7 | O8M | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.446 | |
| 3h4g | FID | Alcohol dehydrogenase [NADP(+)] | 1.1.1.2 | 0.446 | |
| 3irh | DTP | HD domain protein | / | 0.446 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.446 | |
| 4frj | DWB | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4h3i | 10V | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4j7x | SAS | Sepiapterin reductase | 1.1.1.153 | 0.446 | |
| 4msg | 2C6 | Tankyrase-1 | 2.4.2.30 | 0.446 | |
| 4ami | G90 | Beta-1 adrenergic receptor | / | 0.446 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1ij8 | BNI | Avidin | / | 0.445 | |
| 1ja1 | FMN | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 1kyy | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.445 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 1rpw | DID | HTH-type transcriptional regulator QacR | / | 0.445 | |
| 1sa5 | BMV | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.445 | |
| 2duz | ZST | Aldose reductase | 1.1.1.21 | 0.445 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.445 | |
| 2fap | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.445 | |
| 2fap | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.445 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 2v57 | PRL | TetR family transcriptional regulator | / | 0.445 | |
| 2wvl | GDD | Mannosyl-3-phosphogylcerate synthase | / | 0.445 | |
| 2xlt | NA0 | Putative flavin-containing monooxygenase | / | 0.445 | |
| 2y03 | 5FW | Beta-1 adrenergic receptor | / | 0.445 | |
| 2znk | 31U | Prothrombin | 3.4.21.5 | 0.445 | |
| 2zsb | ADP | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 2zse | ACP | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3eon | 341 | Glutaryl-CoA dehydrogenase | / | 0.445 | |
| 3ews | ADP | ATP-dependent RNA helicase DDX19B | 3.6.4.13 | 0.445 | |
| 3f90 | FMN | Flavodoxin | / | 0.445 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.445 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.445 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.445 | |
| 3x04 | GNP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.445 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.445 | |
| 4amj | CVD | Beta-1 adrenergic receptor | / | 0.445 | |
| 4b65 | FAD | L-ornithine N(5)-monooxygenase | / | 0.445 | |
| 4ckr | DI1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.445 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 4fj0 | HHF | 17beta-hydroxysteroid dehydrogenase | / | 0.445 | |
| 4gtr | 7TR | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.445 | |
| 4j1e | 1HM | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.445 | |
| 4kn2 | LYA | Folate receptor beta | / | 0.445 | |
| 1ah0 | SBI | Aldose reductase | 1.1.1.21 | 0.444 | |
| 1clq | GDP | DNA-directed DNA polymerase | / | 0.444 | |
| 1eqb | FFO | Serine hydroxymethyltransferase | 2.1.2.1 | 0.444 | |
| 1m67 | BOA | Glycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal | 1.1.1.8 | 0.444 | |
| 1n4q | LYS_CYS_VAL_ILE_LEU | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.444 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.444 | |
| 1q83 | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.444 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.444 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.444 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 2hvo | ZST | Aldose reductase | 1.1.1.21 | 0.444 | |
| 2hzq | STR | Apolipoprotein D | / | 0.444 | |
| 2pdf | ZST | Aldose reductase | 1.1.1.21 | 0.444 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.444 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.444 | |
| 2v3h | I25 | Prothrombin | 3.4.21.5 | 0.444 | |
| 2wnb | C5P | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 | 2.4.99.4 | 0.444 | |
| 2y67 | N21 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.444 | |
| 3arz | I5I | Chitinase A | / | 0.444 | |
| 3bj7 | COA | Diamine acetyltransferase 1 | / | 0.444 | |
| 3djl | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.444 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3ght | LDT | Aldose reductase | 1.1.1.21 | 0.444 | |
| 3gi2 | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3h0b | B35 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3nlj | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.444 | |
| 3ojg | HL4 | Phosphotriesterase | / | 0.444 | |
| 3qpg | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.444 | |
| 3sfx | JAN | Uncharacterized protein | / | 0.444 | |
| 3zm6 | 2GN | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.444 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.444 | |
| 4buf | F36 | Tankyrase-2 | 2.4.2.30 | 0.444 | |
| 3nya | JTZ | Beta-2 adrenergic receptor | / | 0.444 | |
| 1by5 | GLY_GLY_GLY_AHO_AHO_AHO_FE | Ferrichrome-iron receptor | / | 0.443 | |
| 1df8 | BTN | Streptavidin | / | 0.443 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1lgt | BP3 | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.443 | |
| 1m9k | 7NI | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.443 | |
| 1n43 | BTN | Streptavidin | / | 0.443 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.443 | |
| 1oj4 | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.443 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 1xb1 | ALA_VAL_PRO_ILE_ALA | Baculoviral IAP repeat-containing protein 8 | / | 0.443 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.443 | |
| 2a5c | 8DA | Avidin | / | 0.443 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.443 | |
| 2fa3 | ACO | Hydroxymethylglutaryl-CoA synthase | / | 0.443 | |
| 2iya | ZIO | Oleandomycin glycosyltransferase | / | 0.443 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 2pzn | 393 | Aldose reductase | 1.1.1.21 | 0.443 | |
| 2r0p | K2C | Putative FAD-monooxygenase | / | 0.443 | |
| 2rcw | AAI | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.443 | |
| 2zwa | SAH | tRNA wybutosine-synthesizing protein 4 | 2.1.1.290 | 0.443 | |
| 3c15 | FOK | Adenylate cyclase type 2 | / | 0.443 | |
| 3c15 | FOK | Adenylate cyclase type 5 | / | 0.443 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3euf | BAU | Uridine phosphorylase 1 | / | 0.443 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.443 | |
| 3jqg | AX6 | Pteridine reductase, putative | / | 0.443 | |
| 3pnf | 8BX | Nitric oxide synthase, brain | 1.14.13.39 | 0.443 | |
| 3rga | ILD | Epoxide hydrolase LasB | 5.5.1 | 0.443 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 3szf | DCQ | Sulfide-quinone reductase | / | 0.443 | |
| 4af7 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.443 | |
| 4ajg | F07 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 4bfq | 083 | Soluble acetylcholine receptor | / | 0.443 | |
| 4gdp | FAD | Polyamine oxidase FMS1 | / | 0.443 | |
| 4gr9 | 372 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.443 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4pzs | ACO | Histone acetyltransferase p300 | / | 0.443 | |
| 4xnh | ACO | N-terminal acetyltransferase A complex subunit NAT5 | 2.3.1 | 0.443 | |
| 1buc | FAD | Acyl-CoA dehydrogenase, short-chain specific | 1.3.8.1 | 0.442 | |
| 1fxu | GU7 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.442 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 1sri | DMB | Streptavidin | / | 0.442 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.442 | |
| 2b04 | CHO | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.442 | |
| 2eju | SAH | tRNA (guanine(26)-N(2))-dimethyltransferase | / | 0.442 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.442 | |
| 2g27 | 4LG | Renin | 3.4.23.15 | 0.442 | |
| 2qxw | LDT | Aldose reductase | 1.1.1.21 | 0.442 | |
| 2rku | R78 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.442 | |
| 2rto | IMI | Streptavidin | / | 0.442 | |
| 2vqb | FAD | Putative flavin-containing monooxygenase | / | 0.442 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.442 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.442 | |
| 3e30 | ED4 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.442 | |
| 3ele | PLP | Aminotransferase | / | 0.442 | |
| 3o9l | LPN | Renin | 3.4.23.15 | 0.442 | |
| 3rql | X2D | Nitric oxide synthase, brain | 1.14.13.39 | 0.442 | |
| 4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.442 | |
| 4bz8 | J38 | Histone deacetylase | / | 0.442 | |
| 4h7c | 10H | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 4hej | 14D | Thymidylate kinase | / | 0.442 | |
| 4i9z | 5BA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.442 | |
| 4iil | RBF | Membrane lipoprotein TpN38(b) | / | 0.442 | |
| 4iwv | 1J9 | Glucokinase | 2.7.1.2 | 0.442 | |
| 4k39 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.442 | |
| 4lrh | FOL | Folate receptor alpha | / | 0.442 | |
| 4nbi | D3Y | D-tyrosyl-tRNA(Tyr) deacylase | / | 0.442 | |
| 4tlx | FDA | KtzI | / | 0.442 | |
| 3pbl | ETQ | D(3) dopamine receptor | / | 0.442 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1e2l | TMC | Thymidine kinase | / | 0.441 | |
| 1esm | COA | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 1map | KET | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.441 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 1t41 | ID5 | Aldose reductase | 1.1.1.21 | 0.441 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.441 | |
| 1x2b | STX | Proline iminopeptidase | 3.4.11.5 | 0.441 | |
| 2bak | AQZ | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.441 | |
| 2gyw | OBI | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2idv | M7G | Eukaryotic translation initiation factor 4E-1 | / | 0.441 | |
| 2oz5 | 7XY | Uncharacterized protein | / | 0.441 | |
| 2pd5 | ZST | Aldose reductase | 1.1.1.21 | 0.441 | |
| 2qx7 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.441 | |
| 2r0c | FAD | Putative FAD-monooxygenase | / | 0.441 | |
| 2re8 | GSU | Glutamine--tRNA ligase | 6.1.1.18 | 0.441 | |
| 2v5u | FMN | Flavodoxin | / | 0.441 | |
| 2wuu | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 2xnp | WCX | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.441 | |
| 3c4h | DRL | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.441 | |
| 3clx | X22 | E3 ubiquitin-protein ligase XIAP | 6.3.2 | 0.441 | |
| 3dzj | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.441 | |
| 3gx9 | TXD | Morphinone reductase | / | 0.441 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 3r94 | FLR | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 3ugr | IMN | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 3zhv | TDW | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.441 | |
| 4a33 | PS8 | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.441 | |
| 4a9y | AQZ | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 4bud | 29F | Tankyrase-2 | 2.4.2.30 | 0.441 | |
| 4bux | F35 | Tankyrase-2 | 2.4.2.30 | 0.441 | |
| 4cb5 | 93G | Polymerase basic protein 2 | / | 0.441 | |
| 4epq | 0RR | Poly(ADP-ribose) glycohydrolase | / | 0.441 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.441 | |
| 4jt8 | 1NR | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.441 | |
| 4l33 | F70 | Tankyrase-2 | 2.4.2.30 | 0.441 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 4xba | GMP | Aprataxin-like protein | 3 | 0.441 | |
| 4ybn | FAD | Flavin-nucleotide-binding protein | / | 0.441 | |
| 4z87 | GDP | Inosine-5'-monophosphate dehydrogenase | / | 0.441 | |
| 5ah5 | LSS | Leucine--tRNA ligase | / | 0.441 | |
| 5c93 | ACP | Two-component system histidine protein kinase | / | 0.441 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.440 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.440 | |
| 1qv1 | CZH | Obelin | / | 0.440 | |
| 1srg | MHB | Streptavidin | / | 0.440 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.440 | |
| 1w22 | NHB | Histone deacetylase 8 | 3.5.1.98 | 0.440 | |
| 1xi2 | CB1 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.440 | |
| 1xmm | M7G | m7GpppX diphosphatase | 3.6.1.59 | 0.440 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 2bfa | CB3 | Pteridine reductase 1 | 1.5.1.33 | 0.440 | |
| 2f8p | CEI | Obelin | / | 0.440 | |
| 2fb3 | 5AD | GTP 3',8-cyclase | 4.1.99.18 | 0.440 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.440 | |
| 2h2e | SA8 | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.440 | |
| 2i17 | LDT | Aldose reductase | 1.1.1.21 | 0.440 | |
| 2o6h | INI | 6,7-dimethyl-8-ribityllumazine synthase 1 | 2.5.1.78 | 0.440 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 2rtg | BTN | Streptavidin | / | 0.440 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.440 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.440 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.440 | |
| 3fui | 812 | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.440 | |
| 3g5e | Q74 | Aldose reductase | 1.1.1.21 | 0.440 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.440 | |
| 3jq8 | DX3 | Pteridine reductase, putative | / | 0.440 | |
| 3l06 | SN0 | N-acetylornithine carbamoyltransferase | 2.1.3.9 | 0.440 | |
| 3lnb | COA | N-acetyltransferase family protein | / | 0.440 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3up3 | XCA | aceDAF-12 | / | 0.440 | |
| 4b52 | RDF | Bacillolysin | / | 0.440 | |
| 4br3 | U85 | Choline kinase alpha | 2.7.1.32 | 0.440 | |
| 4dkb | DUN | Deoxyuridine triphosphatase, putative | / | 0.440 | |
| 4fx2 | FMN | Flavodoxin | / | 0.440 | |
| 4h12 | SAH | Histone-lysine N-methyltransferase SETD2 | 2.1.1.43 | 0.440 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 4ise | 1FW | Glucokinase | 2.7.1.2 | 0.440 | |
| 4mmd | 29E | Na(+):neurotransmitter symporter (Snf family) | / | 0.440 | |
| 4wkb | TDI | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | / | 0.440 | |
| 5a01 | 12V | O-glycosyltransferase | / | 0.440 |