sc-PDB

List of CHEMBLId :

This value allows a number of roughly comparable measures of half-maximal response concentration/potency/affinity to be compared on a negative logarithmic scale (e.g., an IC50 measurement of 1nM would have a pChEMBL value of 9).

Uniprot Annotation

Name:	Protein farnesyltransferase subunit beta
ID:	FNTB_RAT
AC:	Q02293
Organism:	Rattus norvegicus
Reign:	Eukaryota
TaxID:	10116
EC Number:	2.5.1.58

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Chains:

Chain Name:	Percentage of Residues within binding site
A	12 %
B	88 %

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Ligand binding site composition:

B-Factor:	23.832
Number of residues:	25
Including
Standard Amino Acids:	23
Non Standard Amino Acids:	1
Water Molecules:	1
Cofactors:
Metals:	ZN

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Cavity properties

Ligandability	Volume (Å3)
0.834	1326.375

% Hydrophobic	% Polar
39.69	60.31
According to VolSite

HET Code:	3PZ
Formula:	C29H29N5O3S
Molecular weight:	527.637 g/mol
DrugBank ID:	-
Buried Surface Area:	47.41 %
Polar Surface area:	99.83 Å2

Number of
H-Bond Acceptors:	6
H-Bond Donors:	0
Rings:	5
Aromatic rings:	4
Anionic atoms:	0
Cationic atoms:	0
Rule of Five Violation:	1
Rotatable Bonds:	7

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Mass center Coordinates

X	Y	Z
51.0665	-50.9943	4.20639

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