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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3pz43PZProtein farnesyltransferase subunit beta2.5.1.58

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3pz43PZProtein farnesyltransferase subunit beta2.5.1.581.000
1s63778Protein farnesyltransferase subunit beta2.5.1.580.590
1sa5BMVProtein farnesyltransferase subunit beta2.5.1.580.577
1mzcBNEProtein farnesyltransferase subunit beta2.5.1.580.570
1jcq739Protein farnesyltransferase subunit beta2.5.1.580.568
3e33ED7Protein farnesyltransferase subunit beta2.5.1.580.568
1o1s1NHProtein farnesyltransferase subunit beta2.5.1.580.562
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.557
1sa4JANProtein farnesyltransferase subunit beta2.5.1.580.553
3e30ED4Protein farnesyltransferase subunit beta2.5.1.580.553
1ld8U49Protein farnesyltransferase subunit beta2.5.1.580.548
4gto7TOProtein farnesyltransferase subunit beta2.5.1.580.537
2h6iCYS_VAL_LEU_SER_GERProtein farnesyltransferase subunit beta2.5.1.580.531
3ksqZ96Protein farnesyltransferase subunit beta2.5.1.580.530
1ld7U66Protein farnesyltransferase subunit beta2.5.1.580.526
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.518
2r2lPB9Protein farnesyltransferase subunit beta2.5.1.580.506
4gtr7TRProtein farnesyltransferase subunit beta2.5.1.580.498
1nl4HFPProtein farnesyltransferase subunit beta2.5.1.580.488
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.484
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.484
3sfy3FYUncharacterized protein/0.460
3q7fED2Uncharacterized protein/0.459
4gtm7TMProtein farnesyltransferase subunit beta2.5.1.580.459
4gtp7TPProtein farnesyltransferase subunit beta2.5.1.580.449
2f0y3MNProtein farnesyltransferase subunit beta2.5.1.580.444
3hxfBD9Geranylgeranyl transferase type-2 subunit beta2.5.1.600.441