sc-PDB

List of CHEMBLId :

This value allows a number of roughly comparable measures of half-maximal response concentration/potency/affinity to be compared on a negative logarithmic scale (e.g., an IC50 measurement of 1nM would have a pChEMBL value of 9).

Uniprot Annotation

Name:	Protein farnesyltransferase subunit beta
ID:	FNTB_RAT
AC:	Q02293
Organism:	Rattus norvegicus
Reign:	Eukaryota
TaxID:	10116
EC Number:	2.5.1.58

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Chains:

Chain Name:	Percentage of Residues within binding site
A	6 %
B	94 %

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Ligand binding site composition:

B-Factor:	35.694
Number of residues:	31
Including
Standard Amino Acids:	29
Non Standard Amino Acids:	1
Water Molecules:	1
Cofactors:
Metals:	ZN

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Cavity properties

Ligandability	Volume (Å3)
0.563	681.750

% Hydrophobic	% Polar
43.56	56.44
According to VolSite

HET Code:	7TP
Formula:	C33H32N4O6S
Molecular weight:	612.695 g/mol
DrugBank ID:	-
Buried Surface Area:	47.52 %
Polar Surface area:	126.49 Å2

Number of
H-Bond Acceptors:	7
H-Bond Donors:	1
Rings:	6
Aromatic rings:	5
Anionic atoms:	0
Cationic atoms:	0
Rule of Five Violation:	1
Rotatable Bonds:	9

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Mass center Coordinates

X	Y	Z
51.3104	51.7714	-4.18725

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