sc-PDB

List of CHEMBLId :

This value allows a number of roughly comparable measures of half-maximal response concentration/potency/affinity to be compared on a negative logarithmic scale (e.g., an IC50 measurement of 1nM would have a pChEMBL value of 9).

Uniprot Annotation

Name:	S-adenosylmethionine decarboxylase proenzyme
ID:	DCAM_HUMAN
AC:	P17707
Organism:	Homo sapiens
Reign:	Eukaryota
TaxID:	9606
EC Number:	4.1.1.50

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Chains:

Chain Name:	Percentage of Residues within binding site
B	29 %
A	71 %

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Ligand binding site composition:

B-Factor:	23.196
Number of residues:	23
Including
Standard Amino Acids:	23
Non Standard Amino Acids:	0
Water Molecules:	0
Cofactors:
Metals:

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Cavity properties

Ligandability	Volume (Å3)
0.315	425.250

% Hydrophobic	% Polar
39.68	60.32
According to VolSite

HET Code:	MGB
Formula:	C5H14N8
Molecular weight:	186.218 g/mol
DrugBank ID:	-
Buried Surface Area:	63.6 %
Polar Surface area:	152 Å2

Number of
H-Bond Acceptors:	6
H-Bond Donors:	6
Rings:	0
Aromatic rings:	0
Anionic atoms:	0
Cationic atoms:	2
Rule of Five Violation:	1
Rotatable Bonds:	5

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Mass center Coordinates

X	Y	Z
-17.0312	-6.00215	7.03015

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