sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4f1t | H52 | Probable serine/threonine-protein kinase roco4 | 2.7.11.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4f1t | H52 | Probable serine/threonine-protein kinase roco4 | 2.7.11.1 | 1.000 | |
| 4f1m | ACP | Probable serine/threonine-protein kinase roco4 | 2.7.11.1 | 0.568 | |
| 2rku | R78 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.548 | |
| 4f1o | ACP | Probable serine/threonine-protein kinase roco4 | 2.7.11.1 | 0.546 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.539 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.537 | |
| 2ewa | SB2 | Mitogen-activated protein kinase 14 | / | 0.526 | |
| 2vz0 | D64 | Pteridine reductase | / | 0.526 | |
| 3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.526 | |
| 4f0f | ACP | Probable serine/threonine-protein kinase roco4 | 2.7.11.1 | 0.526 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.524 | |
| 4at4 | T6E | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.520 | |
| 4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.520 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.519 | |
| 3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.518 | |
| 3jq8 | DX3 | Pteridine reductase, putative | / | 0.516 | |
| 1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.515 | |
| 4a4o | 664 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.514 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.512 | |
| 2fjm | 073 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.511 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.509 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.508 | |
| 4ckr | DI1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.508 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.507 | |
| 2og8 | 1N8 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.507 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.506 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.505 | |
| 3jq7 | DX2 | Pteridine reductase, putative | / | 0.505 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.505 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.505 | |
| 1kmv | LII | Dihydrofolate reductase | 1.5.1.3 | 0.504 | |
| 1rgs | CMP | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.504 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.504 | |
| 2cl5 | BIE | Catechol O-methyltransferase | 2.1.1.6 | 0.504 | |
| 3bur | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.504 | |
| 2xk4 | OL2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.503 | |
| 4fex | 0TO | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.503 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.503 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.502 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.502 | |
| 3p9t | TCL | Repressor | / | 0.502 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.502 | |
| 1p33 | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.501 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.501 | |
| 2w5b | AGS | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.501 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.501 | |
| 4kd7 | 9DR | Dihydrofolate reductase | 1.5.1.3 | 0.501 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.500 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.500 | |
| 3k45 | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.500 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.500 | |
| 1kij | NOV | DNA gyrase subunit B | / | 0.499 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.499 | |
| 2x9v | TMQ | Pteridine reductase | / | 0.499 | |
| 3hv3 | R49 | Mitogen-activated protein kinase 14 | / | 0.499 | |
| 4j52 | 1J3 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.499 | |
| 4a4x | JUP | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.498 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.498 | |
| 1fgi | SU1 | Fibroblast growth factor receptor 1 | / | 0.497 | |
| 1hfr | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.497 | |
| 1uwh | BAX | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.497 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.497 | |
| 3hyw | DCQ | Sulfide-quinone reductase | / | 0.497 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.497 | |
| 1s3y | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.496 | |
| 1xng | DND | NH(3)-dependent NAD(+) synthetase | 6.3.1.5 | 0.496 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.496 | |
| 2osc | MUH | Angiopoietin-1 receptor | 2.7.10.1 | 0.496 | |
| 2q2y | ADP | Kinesin-like protein KIF11 | / | 0.496 | |
| 2xk7 | 30E | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.496 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.496 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.496 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.495 | |
| 1u72 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.495 | |
| 1zyd | ATP | eIF-2-alpha kinase GCN2 | / | 0.495 | |
| 2xnp | WCX | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.495 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.495 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.495 | |
| 3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.494 | |
| 3gyf | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.494 | |
| 4few | PP2 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.494 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.493 | |
| 1syn | F89 | Thymidylate synthase | / | 0.493 | |
| 4afe | GGY | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.493 | |
| 4kyk | IMN | Lactoylglutathione lyase | 4.4.1.5 | 0.493 | |
| 4zhi | ADP | Kinesin-like protein KIF11 | / | 0.493 | |
| 2owb | 626 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.492 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.492 | |
| 3jqg | AX6 | Pteridine reductase, putative | / | 0.492 | |
| 3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.492 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.492 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.492 | |
| 1e1n | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.491 | |
| 1lwl | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.491 | |
| 1r8q | AFB | Cytohesin-2 | / | 0.491 | |
| 1r8q | AFB | ADP-ribosylation factor 1 | / | 0.491 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.491 | |
| 1s9d | AFB | Cytohesin-2 | / | 0.491 | |
| 1s9d | AFB | ADP-ribosylation factor 1 | / | 0.491 | |
| 2pl0 | STI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.491 | |
| 2wd8 | VGF | Pteridine reductase | / | 0.491 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.491 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.491 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.491 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.490 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.490 | |
| 1tg5 | 645 | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.490 | |
| 1zy5 | ANP | eIF-2-alpha kinase GCN2 | / | 0.490 | |
| 4lsj | LSJ | Glucocorticoid receptor | / | 0.490 | |
| 1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.489 | |
| 2r6j | NDP | Eugenol synthase 1 | 1.1.1.318 | 0.489 | |
| 3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.489 | |
| 3nn6 | HNK | 6-hydroxy-L-nicotine oxidase | / | 0.489 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.489 | |
| 4n4t | 2GV | Tankyrase-1 | 2.4.2.30 | 0.489 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.489 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 1rc4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 3gn2 | AX8 | Pteridine reductase | / | 0.488 | |
| 3jqb | DX6 | Pteridine reductase, putative | / | 0.488 | |
| 3n39 | FMN | Protein NrdI | / | 0.488 | |
| 4gki | 0JN | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.488 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.488 | |
| 4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.488 | |
| 3rfm | CFF | Adenosine receptor A2a | / | 0.488 | |
| 2fmn | 4HF | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.487 | |
| 3sl6 | JN8 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.487 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.487 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.486 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.486 | |
| 2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.486 | |
| 3tgu | WF3 | Cytochrome b | / | 0.486 | |
| 4bkj | STI | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.486 | |
| 4fev | PP1 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.486 | |
| 5bvw | 1N1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.486 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.486 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.485 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.485 | |
| 3up0 | D7S | aceDAF-12 | / | 0.485 | |
| 4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.485 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.485 | |
| 1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.484 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.484 | |
| 3d80 | Q22 | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 3e5a | VX6 | Aurora kinase A | 2.7.11.1 | 0.484 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.484 | |
| 4c2j | COA | 3-ketoacyl-CoA thiolase, mitochondrial | 2.3.1.16 | 0.484 | |
| 4equ | G6I | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.484 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.484 | |
| 4x5j | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 1djq | FMN | Trimethylamine dehydrogenase | 1.5.8.2 | 0.483 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.483 | |
| 2hzq | STR | Apolipoprotein D | / | 0.483 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.483 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.483 | |
| 3uq6 | ADN | Putative adenosine kinase | / | 0.483 | |
| 4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.483 | |
| 1e7w | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.482 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.482 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.482 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.482 | |
| 2gm1 | ADP | Kinesin-like protein KIF11 | / | 0.482 | |
| 2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.482 | |
| 2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.482 | |
| 2yhu | WHF | Pteridine reductase | / | 0.482 | |
| 2zu9 | GDP | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.482 | |
| 1nd5 | 2BF | Prostatic acid phosphatase | 3.1.3.2 | 0.481 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.481 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.481 | |
| 3zo7 | K6H | Muconolactone Delta-isomerase | / | 0.481 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.481 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.480 | |
| 3gi2 | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.480 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.480 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.480 | |
| 4ej1 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.480 | |
| 4jq3 | ZOM | Aldo-keto reductase family 1 member C2 | / | 0.480 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.480 | |
| 4n82 | FMN | Ribonucleotide reductase (NrdI family protein), putative | / | 0.480 | |
| 5epe | SAH | Uncharacterized protein | / | 0.480 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.480 | |
| 1ne6 | SP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.479 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.479 | |
| 2bxo | OPB | Serum albumin | / | 0.479 | |
| 2f98 | NGV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.479 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.479 | |
| 3cqe | P91 | Wee1-like protein kinase | 2.7.10.2 | 0.479 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.479 | |
| 4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.479 | |
| 4utl | FNR | Xenobiotic reductase | / | 0.479 | |
| 4z87 | GDP | Inosine-5'-monophosphate dehydrogenase | / | 0.479 | |
| 5ab6 | CAA | Nonspecific lipid-transfer protein, putative | / | 0.479 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.479 | |
| 1fcx | 184 | Retinoic acid receptor gamma | / | 0.478 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.478 | |
| 2in6 | 839 | Wee1-like protein kinase | 2.7.10.2 | 0.478 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 3cas | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.478 | |
| 3htj | ET | EbrA repressor | / | 0.478 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.478 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.478 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.477 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.477 | |
| 2b01 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.477 | |
| 3eta | 351 | Insulin receptor | 2.7.10.1 | 0.477 | |
| 3g4l | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.477 | |
| 4bfr | J82 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 2.7.1.153 | 0.477 | |
| 4jqa | ID8 | Aldo-keto reductase family 1 member C2 | / | 0.477 | |
| 4m6k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.477 | |
| 1fd0 | 254 | Retinoic acid receptor gamma | / | 0.476 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.476 | |
| 1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.476 | |
| 1tsd | F89 | Thymidylate synthase | / | 0.476 | |
| 1w2c | ANP | Inositol-trisphosphate 3-kinase A | 2.7.1.127 | 0.476 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.476 | |
| 2io6 | 330 | Wee1-like protein kinase | 2.7.10.2 | 0.476 | |
| 3lm4 | HPX | Catechol 2,3-dioxygenase | / | 0.476 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.476 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.476 | |
| 4kfj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 4li6 | 1XO | Tankyrase-1 | 2.4.2.30 | 0.476 | |
| 4m48 | 21B | Sodium-dependent dopamine transporter | / | 0.476 | |
| 4pl9 | ADP | Ethylene receptor 1 | / | 0.476 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.476 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 1ly3 | COG | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 1pd8 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 2e99 | B08 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.475 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.475 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.475 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.475 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.475 | |
| 3l70 | JZV | Cytochrome b | / | 0.475 | |
| 3v0m | 5GW | Histo-blood group ABO system transferase | / | 0.475 | |
| 4jln | 18V | Deoxycytidine kinase | 2.7.1.74 | 0.475 | |
| 4k6i | 9RA | Retinoic acid receptor RXR-alpha | / | 0.475 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.475 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.474 | |
| 1m7a | MQU | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 1u0w | STL | Chalcone synthase 2 | 2.3.1.74 | 0.474 | |
| 2c42 | TPP | Pyruvate synthase | / | 0.474 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.474 | |
| 2ph5 | NAD | Homospermidine synthase | / | 0.474 | |
| 2xnm | WGZ | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.474 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.474 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.474 | |
| 4i5x | FLF | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.474 | |
| 4daj | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.474 | |
| 1bvr | THT | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.473 | |
| 1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 2a19 | ANP | Interferon-induced, double-stranded RNA-activated protein kinase | 2.7.11.1 | 0.473 | |
| 2jh0 | 701 | Prothrombin | 3.4.21.5 | 0.473 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.473 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.473 | |
| 3cth | 319 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.473 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.473 | |
| 3p6n | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.473 | |
| 4ddr | MMV | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 4gh3 | 0EV | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.473 | |
| 5bp7 | SAH | SAM-dependent methyltransferase | / | 0.473 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.472 | |
| 1o6r | R19 | Squalene--hopene cyclase | 4.2.1.129 | 0.472 | |
| 1rdt | L79 | Retinoic acid receptor RXR-alpha | / | 0.472 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.472 | |
| 3o73 | O73 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.472 | |
| 3oez | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.472 | |
| 3sgy | 06W | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 3thr | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.472 | |
| 3upy | FOM | Oxidoreductase, putative | / | 0.472 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.472 | |
| 4h6z | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.472 | |
| 4hsh | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.472 | |
| 5ab7 | MLC | Nonspecific lipid-transfer protein, putative | / | 0.472 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.471 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.471 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.471 | |
| 1s6q | TPB | Gag-Pol polyprotein | 2.7.7.49 | 0.471 | |
| 1yrs | ADP | Kinesin-like protein KIF11 | / | 0.471 | |
| 2ban | 357 | Gag-Pol polyprotein | 2.7.7.49 | 0.471 | |
| 2g2h | P16 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.471 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.471 | |
| 2x20 | PID | Peridinin-chlorophyll a-binding protein 1, chloroplastic | / | 0.471 | |
| 2xae | ADP | Kinesin-like protein KIF11 | / | 0.471 | |
| 2xkd | T3M | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.471 | |
| 3be2 | RAJ | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.471 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.471 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.471 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.471 | |
| 3dau | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 3eon | 341 | Glutaryl-CoA dehydrogenase | / | 0.471 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.471 | |
| 3nxt | D2E | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 4a4l | 939 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.471 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.471 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.471 | |
| 1buc | FAD | Acyl-CoA dehydrogenase, short-chain specific | 1.3.8.1 | 0.470 | |
| 1fml | RTL | Retinol dehydratase | / | 0.470 | |
| 1s3w | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 1x8b | 824 | Wee1-like protein kinase | 2.7.10.2 | 0.470 | |
| 2blb | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.470 | |
| 2c3o | TPP | Pyruvate synthase | / | 0.470 | |
| 2clf | F6F | Tryptophan synthase alpha chain | / | 0.470 | |
| 2d06 | EST | Sulfotransferase 1A1 | 2.8.2.1 | 0.470 | |
| 2x2r | ADP | Kinesin-like protein KIF11 | / | 0.470 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.470 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.470 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.470 | |
| 4gh1 | 0WX | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.470 | |
| 4hni | 16W | Casein kinase I isoform epsilon | 2.7.11.1 | 0.470 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.470 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.470 | |
| 1maq | PGU | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.469 | |
| 1mzn | BM6 | Retinoic acid receptor RXR-alpha | / | 0.469 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 1sqq | OST | Cytochrome b | / | 0.469 | |
| 1t13 | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | / | 0.469 | |
| 1yho | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 2l98 | STL | Troponin C, slow skeletal and cardiac muscles | / | 0.469 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.469 | |
| 3d73 | NBB | Pheromone-binding protein ASP1 | / | 0.469 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.469 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.469 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.469 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.469 | |
| 4fny | I3K | ALK tyrosine kinase receptor | 2.7.10.1 | 0.469 | |
| 4qij | 1HA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.469 | |
| 1lud | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 1ot3 | THM | Deoxynucleoside kinase | / | 0.468 | |
| 2bak | AQZ | Mitogen-activated protein kinase 14 | / | 0.468 | |
| 2clh | F19 | Tryptophan synthase alpha chain | / | 0.468 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.468 | |
| 3ba6 | AN2 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.468 | |
| 3bmq | AX5 | Pteridine reductase | / | 0.468 | |
| 3d74 | NBB | Pheromone-binding protein ASP1 | / | 0.468 | |
| 3fu8 | 3DM | Laccase-1 | 1.10.3.2 | 0.468 | |
| 3jq6 | DX1 | Pteridine reductase, putative | / | 0.468 | |
| 3qls | 55V | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.468 | |
| 4a9y | AQZ | Mitogen-activated protein kinase 14 | / | 0.468 | |
| 4af7 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.468 | |
| 4dlc | UMP | Deoxyuridine triphosphatase, putative | / | 0.468 | |
| 4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.468 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.468 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.468 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.468 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 1rp4 | FAD | Endoplasmic oxidoreductin-1 | 1.8.4 | 0.467 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.467 | |
| 1ybg | TAV | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.467 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.467 | |
| 2agv | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.467 | |
| 2c9e | PID | Peridinin-chlorophyll a protein, high-salt form | / | 0.467 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 3oap | REA | Retinoic acid receptor RXR-alpha | / | 0.467 | |
| 3pz3 | PZ3 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.467 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.467 | |
| 3t8x | T8X | T-cell surface glycoprotein CD1b | / | 0.467 | |
| 3up3 | XCA | aceDAF-12 | / | 0.467 | |
| 4da0 | GNG | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.467 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.467 | |
| 4fc0 | 0T2 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.467 | |
| 4g2y | NI5 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.467 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.467 | |
| 5d0r | B1T | Adenylate cyclase type 10 | / | 0.467 | |
| 1bzf | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1k4g | AIQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.466 | |
| 1rx4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 2dqs | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.466 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.466 | |
| 2xf3 | J01 | Uncharacterized protein | / | 0.466 | |
| 2yac | 937 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.466 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.466 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 3ghw | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 3hu2 | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.466 | |
| 3hxf | BD9 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.466 | |
| 3o9l | LPN | Renin | 3.4.23.15 | 0.466 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.466 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.466 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.466 | |
| 3rgz | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.466 | |
| 4c3y | ANB | 3-ketosteroid dehydrogenase | / | 0.466 | |
| 4h7z | GUN | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.466 | |
| 4ivy | 1GT | Estrogen receptor | / | 0.466 | |
| 4tyj | 0LI | Fibroblast growth factor receptor 4 | 2.7.10.1 | 0.466 | |
| 5hbs | RTL | Retinol-binding protein 1 | / | 0.466 | |
| 3pbl | ETQ | D(3) dopamine receptor | / | 0.466 | |
| 1fm6 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.465 | |
| 1juj | LYA | Thymidylate synthase | 2.1.1.45 | 0.465 | |
| 1k74 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.465 | |
| 1m7b | GTP | Rho-related GTP-binding protein RhoE | / | 0.465 | |
| 1mtc | GPR | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.465 | |
| 1sjw | NGV | Nogalonic acid methyl ester cyclase | / | 0.465 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.465 | |
| 2jav | 5Z5 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.465 | |
| 2jdc | CAO | Probable acetyltransferase | / | 0.465 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.465 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.465 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.465 | |
| 2psj | CEI | Renilla-luciferin 2-monooxygenase | 1.13.12.5 | 0.465 | |
| 2pul | ACP | Methylthioribose kinase | 2.7.1.100 | 0.465 | |
| 2z1w | BDI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.465 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.465 | |
| 3blo | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.465 | |
| 3dg8 | RJ6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.465 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.465 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.465 | |
| 3huc | G97 | Mitogen-activated protein kinase 14 | / | 0.465 | |
| 3iiu | PID | Peridinin-chlorophyll a-binding protein 1, chloroplastic | / | 0.465 | |
| 3l71 | AZO | Cytochrome b | / | 0.465 | |
| 3ntz | 3TZ | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 3nxo | D2B | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.465 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.465 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.465 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.465 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.465 | |
| 4feu | 537 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.465 | |
| 4ixd | 1HV | Integrin alpha-L | / | 0.465 | |
| 4lrr | CF9 | Thymidylate synthase | / | 0.465 | |
| 4lux | QJ8 | Nitric oxide synthase, brain | 1.14.13.39 | 0.465 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.464 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.464 | |
| 1u70 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 2fs4 | PZ1 | Renin | 3.4.23.15 | 0.464 | |
| 2rab | NAD | Glutathione amide reductase | / | 0.464 | |
| 2rbe | ZMG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.464 | |
| 2vez | ACO | Glucosamine 6-phosphate acetyltransferase, putative | / | 0.464 | |
| 2w3w | VG9 | Dihydrofolate reductase | / | 0.464 | |
| 2xkc | 4VQ | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.464 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.464 | |
| 3ol5 | SAW | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.464 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.464 | |
| 4g8c | C6L | Alpha/beta hydrolase fold protein | / | 0.464 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 4iae | 1DX | Alr2278 protein | / | 0.464 | |
| 4ixg | IXG | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 4m2x | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.464 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.464 | |
| 2ycz | I32 | Beta-1 adrenergic receptor | / | 0.464 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.463 | |
| 1xiu | REA | Retinoic acid receptor RXR | / | 0.463 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.463 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.463 | |
| 2b8j | ADN | Class B acid phosphatase | 3.1.3.2 | 0.463 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 2g27 | 4LG | Renin | 3.4.23.15 | 0.463 | |
| 2h44 | 7CA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.463 | |
| 2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.463 | |
| 3bbf | GDP | Nucleoside diphosphate kinase B | 2.7.4.6 | 0.463 | |
| 3c72 | CX1 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.463 | |
| 3fl4 | FL4 | Mitogen-activated protein kinase 14 | / | 0.463 | |
| 3o57 | ZG2 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.463 | |
| 4bwa | N0B | Pyrrolysine--tRNA ligase | / | 0.463 | |
| 4cby | KEE | Histone deacetylase 4 | 3.5.1.98 | 0.463 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.463 | |
| 4nh9 | 2LC | Endoplasmin | / | 0.463 | |
| 4oex | 5EO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.463 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.463 | |
| 1cxz | GSP | Transforming protein RhoA | / | 0.462 | |
| 1dls | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1el4 | CTZ | Obelin | / | 0.462 | |
| 1ivr | CBA | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.462 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.462 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.462 | |
| 2fhj | H4Z | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.462 | |
| 2h42 | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.462 | |
| 2pda | TPP | Pyruvate synthase | / | 0.462 | |
| 2pjl | 047 | Steroid hormone receptor ERR1 | / | 0.462 | |
| 3ar7 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.462 | |
| 3f82 | 353 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.462 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.462 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.462 | |
| 3gie | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.462 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.462 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.462 | |
| 3n0y | APC | Adenylate cyclase 2 | / | 0.462 | |
| 4a51 | DQ8 | Kinesin-like protein KIF11 | / | 0.462 | |
| 4cx3 | HW8 | Nitric oxide synthase, brain | 1.14.13.39 | 0.462 | |
| 4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.462 | |
| 4kao | KAO | Focal adhesion kinase 1 | 2.7.10.2 | 0.462 | |
| 4l17 | DNQ | Glutamate receptor 2 | / | 0.462 | |
| 4nbj | D3Y | D-tyrosyl-tRNA(Tyr) deacylase | / | 0.462 | |
| 4tzt | 468 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.462 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.461 | |
| 1dlr | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1ezf | IN0 | Squalene synthase | 2.5.1.21 | 0.461 | |
| 1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.461 | |
| 1jom | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1n71 | COA | Aac(6')-Ii protein | / | 0.461 | |
| 1q6n | P90 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.461 | |
| 1wpg | ADP | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.461 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.461 | |
| 1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.461 | |
| 2b37 | 8PS | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 2gqf | FAD | Uncharacterized protein HI_0933 | / | 0.461 | |
| 2lbd | REA | Retinoic acid receptor gamma | / | 0.461 | |
| 2oh4 | GIG | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.461 | |
| 2puf | GUN | HTH-type transcriptional repressor PurR | / | 0.461 | |
| 2w0h | NDP | Trypanothione reductase | / | 0.461 | |
| 2zb1 | GK4 | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.461 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.461 | |
| 3of3 | DIH | Purine nucleoside phosphorylase DeoD-type 1 | / | 0.461 | |
| 3wi2 | P98 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.461 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.461 | |
| 4ap0 | ADP | Kinesin-like protein KIF11 | / | 0.461 | |
| 4g1n | NZT | Pyruvate kinase PKM | 2.7.1.40 | 0.461 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 4gtv | 7TR | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.461 | |
| 4jse | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.461 | |
| 4jtr | IZP | Aldo-keto reductase family 1 member C2 | / | 0.461 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.461 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.461 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 1map | KET | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.460 | |
| 1olm | VTQ | SEC14-like protein 2 | / | 0.460 | |
| 1re0 | AFB | ADP-ribosylation factor 1 | / | 0.460 | |
| 1re0 | AFB | ARF guanine-nucleotide exchange factor 1 | / | 0.460 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.460 | |
| 1s2g | 3D1 | Nucleoside 2-deoxyribosyltransferase | / | 0.460 | |
| 1sqb | AZO | Cytochrome b | / | 0.460 | |
| 1w22 | NHB | Histone deacetylase 8 | 3.5.1.98 | 0.460 | |
| 2ewn | BTX | Bifunctional ligase/repressor BirA | / | 0.460 | |
| 2p4i | MR9 | Angiopoietin-1 receptor | 2.7.10.1 | 0.460 | |
| 2pdy | FID | Aldose reductase | 1.1.1.21 | 0.460 | |
| 2xk3 | XK3 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.460 | |
| 2zi5 | 3L1 | Deoxycytidine kinase | 2.7.1.74 | 0.460 | |
| 3cse | N22 | Uncharacterized protein | / | 0.460 | |
| 3drr | R8E | Gag-Pol polyprotein | 2.7.7.49 | 0.460 | |
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.460 | |
| 3lla | ACP | Myosin heavy chain kinase A | 2.7.11.7 | 0.460 | |
| 3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.460 | |
| 3sa1 | 6DR | Dihydrofolate reductase | / | 0.460 | |
| 4aql | TXC | Guanine deaminase | 3.5.4.3 | 0.460 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.460 | |
| 4c6z | TLE | 3-oxoacyl-ACP synthase | / | 0.460 | |
| 4ea1 | 3RX | Dehydrosqualene synthase | / | 0.460 | |
| 4ea2 | RWZ | Dehydrosqualene synthase | / | 0.460 | |
| 4gvq | N4M | Methenyltetrahydromethanopterin cyclohydrolase | 3.5.4.27 | 0.460 | |
| 4gvs | F4M | Methenyltetrahydromethanopterin cyclohydrolase | 3.5.4.27 | 0.460 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.460 | |
| 4k9y | K9Y | Focal adhesion kinase 1 | 2.7.10.2 | 0.460 | |
| 4phl | PIL | Phosphodiesterase | / | 0.460 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.459 | |
| 1q66 | KMB | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.459 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.459 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.459 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.459 | |
| 1zp4 | C2F | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.459 | |
| 2jbl | SMA | Reaction center protein L chain | / | 0.459 | |
| 2oth | NIM | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.459 | |
| 2pg2 | ADP | Kinesin-like protein KIF11 | / | 0.459 | |
| 2vi5 | Y19 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.459 | |
| 2wpw | ACO | Orf14 | / | 0.459 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.459 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 3fnf | JPM | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.459 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 3sl8 | JN7 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.459 | |
| 3tfj | THG | Dimethylsulfonioproprionate demethylase DmdA | 2.1.1.269 | 0.459 | |
| 3v4e | COA | Putative acetyltransferase SACOL2570 | 2.3.1 | 0.459 | |
| 3wiy | LC6 | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.459 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.459 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.459 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 4i9z | 5BA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.459 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.459 | |
| 4uoh | ADP | Nucleoside diphosphate kinase | / | 0.459 | |
| 5bt4 | 2LO | Bromodomain-containing protein 4 | / | 0.459 | |
| 4ami | G90 | Beta-1 adrenergic receptor | / | 0.459 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.458 | |
| 1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.458 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.458 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.458 | |
| 1xu7 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.458 | |
| 1xuo | LA1 | Integrin alpha-L | / | 0.458 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
| 1z4i | UMP | 5'(3')-deoxyribonucleotidase, mitochondrial | 3.1.3 | 0.458 | |
| 2b04 | CHO | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.458 | |
| 2f99 | AKV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.458 | |
| 2mm3 | CHO | Gastrotropin | / | 0.458 | |
| 2trs | IPL | Tryptophan synthase alpha chain | / | 0.458 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.458 | |
| 3c6o | 2S2 | Protein TRANSPORT INHIBITOR RESPONSE 1 | / | 0.458 | |
| 3cr7 | PPS | Adenylyl-sulfate kinase | 2.7.1.25 | 0.458 | |
| 3neg | PYV | Abscisic acid receptor PYL1 | / | 0.458 | |
| 3nxu | RIT | Cytochrome P450 3A4 | / | 0.458 | |
| 3roe | THM | NAD(P)H-hydrate epimerase | 5.1.99.6 | 0.458 | |
| 3s41 | S41 | Glucokinase | 2.7.1.2 | 0.458 | |
| 3v0n | 4GW | Histo-blood group ABO system transferase | / | 0.458 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.458 | |
| 3vw8 | DF6 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.458 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.458 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.458 | |
| 1jtu | LYB | Thymidylate synthase | / | 0.457 | |
| 1knp | FAD | L-aspartate oxidase | 1.4.3.16 | 0.457 | |
| 1kyz | FER | Caffeic acid 3-O-methyltransferase | 2.1.1.68 | 0.457 | |
| 1mab | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.457 | |
| 1n1e | NDE | Glycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal | 1.1.1.8 | 0.457 | |
| 1ndy | FR3 | Adenosine deaminase | 3.5.4.4 | 0.457 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.457 | |
| 1zga | HMK | Isoflavone 4'-O-methyltransferase | / | 0.457 | |
| 2azy | CHD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.457 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.457 | |
| 2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.457 | |
| 2cle | F6F | Tryptophan synthase alpha chain | / | 0.457 | |
| 2pdm | ZST | Aldose reductase | 1.1.1.21 | 0.457 | |
| 2pnu | ENM | Androgen receptor | / | 0.457 | |
| 2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.457 | |
| 2xno | ED8 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.457 | |
| 2zoz | ET | Transcriptional regulator | / | 0.457 | |
| 3cv9 | VDX | Vitamin D3 dihydroxylase | / | 0.457 | |
| 3dl9 | V2H | Vitamin D 25-hydroxylase | / | 0.457 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3nhf | VVV | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.457 | |
| 3nta | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.457 | |
| 3r33 | 6ME | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 3tub | FPU | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.457 | |
| 3um8 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.457 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 4f0e | 0RU | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.457 | |
| 4g1c | CNA | NAD-dependent protein deacylase sirtuin-5, mitochondrial | / | 0.457 | |
| 4jtq | FLP | Aldo-keto reductase family 1 member C2 | / | 0.457 | |
| 4kf1 | HT5 | Aryldialkylphosphatase | 3.1.8.1 | 0.457 | |
| 4qii | 2NE | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.457 | |
| 4y6g | F6F | Tryptophan synthase alpha chain | / | 0.457 | |
| 5bsr | COA | 4-coumarate--CoA ligase 2 | 6.2.1.12 | 0.457 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1fcy | 564 | Retinoic acid receptor gamma | / | 0.456 | |
| 1hnv | TBO | Gag-Pol polyprotein | 2.7.7.49 | 0.456 | |
| 1ohj | COP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
| 1p91 | SAM | 23S rRNA (guanine(745)-N(1))-methyltransferase | / | 0.456 | |
| 1pr4 | MTP | Purine nucleoside phosphorylase DeoD-type | / | 0.456 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.456 | |
| 1sqp | MYX | Cytochrome b | / | 0.456 | |
| 1vrq | FON | Subunit alpha of sarocosine oxidase | / | 0.456 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.456 | |
| 2g7y | MO9 | Cathepsin S | 3.4.22.27 | 0.456 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.456 | |
| 2obx | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | 2.5.1.78 | 0.456 | |
| 2q6h | CXX | Na(+):neurotransmitter symporter (Snf family) | / | 0.456 | |
| 2qx7 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.456 | |
| 2vcz | VC3 | Hematopoietic prostaglandin D synthase | / | 0.456 | |
| 2vq3 | NAP | Metalloreductase STEAP3 | / | 0.456 | |
| 2w03 | ADN | AcsD | / | 0.456 | |
| 2wjo | QUD | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 2wqo | VGK | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.456 | |
| 3bqd | DAY | Glucocorticoid receptor | / | 0.456 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.456 | |
| 3oll | EST | Estrogen receptor beta | / | 0.456 | |
| 3pn1 | IVH | DNA ligase | / | 0.456 | |
| 3tpt | ADP | Serine/threonine-protein kinase toxin HipA | / | 0.456 | |
| 3uft | HW7 | Nitric oxide synthase, brain | 1.14.13.39 | 0.456 | |
| 3ug8 | IMN | Aldo-keto reductase family 1 member C3 | / | 0.456 | |
| 3vg9 | ZMA | Adenosine receptor A2a | / | 0.456 | |
| 3zia | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.456 | |
| 4ag7 | COA | Glucosamine 6-phosphate N-acetyltransferase | / | 0.456 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.456 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.456 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.456 | |
| 4da6 | GA2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.456 | |
| 4dm8 | REA | Retinoic acid receptor beta | / | 0.456 | |
| 4e6a | 0O9 | Mitogen-activated protein kinase 14 | / | 0.456 | |
| 4fog | C2F | Thymidylate synthase ThyA | / | 0.456 | |
| 4h4m | 494 | Gag-Pol polyprotein | 2.7.7.49 | 0.456 | |
| 4iw8 | KN3 | Estrogen receptor | / | 0.456 | |
| 4iwv | 1J9 | Glucokinase | 2.7.1.2 | 0.456 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.456 | |
| 4jse | QJ2 | Nitric oxide synthase, brain | 1.14.13.39 | 0.456 | |
| 4jvn | YUG | Estrogen sulfotransferase | 2.8.2.4 | 0.456 | |
| 4y1b | NAP | AntE | / | 0.456 | |
| 5bn4 | ANP | V-type ATP synthase alpha chain | / | 0.456 | |
| 1bx9 | GLY_GGL_FOE | Glutathione S-transferase F2 | 2.5.1.18 | 0.455 | |
| 1ej3 | CZH | Aequorin-2 | / | 0.455 | |
| 1fp1 | HCC | Isoliquiritigenin 2'-O-methyltransferase | / | 0.455 | |
| 1gt5 | BZQ | Odorant-binding protein | / | 0.455 | |
| 1k9s | FM1 | Purine nucleoside phosphorylase DeoD-type | / | 0.455 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.455 | |
| 1qv0 | CZH | Obelin | / | 0.455 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.455 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.455 | |
| 1uhl | MEI | Retinoic acid receptor RXR-beta | / | 0.455 | |
| 2cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.455 | |
| 2jl1 | NAP | Triphenylmethane reductase | / | 0.455 | |
| 2q7g | CCL | Pyrrolysine--tRNA ligase | / | 0.455 | |
| 2vcw | ZZA | Hematopoietic prostaglandin D synthase | / | 0.455 | |
| 3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.455 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3of1 | CMP | cAMP-dependent protein kinase regulatory subunit | / | 0.455 | |
| 4gg7 | 0J8 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.455 | |
| 4hqv | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.455 | |
| 4k5e | 1Q7 | Nitric oxide synthase, brain | 1.14.13.39 | 0.455 | |
| 4wct | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.455 | |
| 4zzj | CNA | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.455 | |
| 5eq1 | BEA | Peregrin | / | 0.455 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.455 | |
| 5d6l | CAU | Beta-2 adrenergic receptor | / | 0.455 | |
| 1e1q | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.454 | |
| 1kl2 | FON | Serine hydroxymethyltransferase | / | 0.454 | |
| 1mvc | BM6 | Retinoic acid receptor RXR-alpha | / | 0.454 | |
| 1t48 | BB3 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.454 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.454 | |
| 2aaz | CB3 | Thymidylate synthase | 2.1.1.45 | 0.454 | |
| 2blc | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.454 | |
| 2dy9 | ADP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.454 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.454 | |
| 2pd9 | FID | Aldose reductase | 1.1.1.21 | 0.454 | |
| 2r04 | W71 | Genome polyprotein | / | 0.454 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.454 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.454 | |
| 3ey4 | 352 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.454 | |
| 3fzs | B96 | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.454 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 3n61 | XFJ | Nitric oxide synthase, brain | 1.14.13.39 | 0.454 | |
| 3qv1 | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic | 1.2.1.13 | 0.454 | |
| 3ufw | HW0 | Nitric oxide synthase, brain | 1.14.13.39 | 0.454 | |
| 3uic | 09T | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.454 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.454 | |
| 4cid | ANP | EH domain-containing protein 2 | / | 0.454 | |
| 4fal | 0T0 | Aldo-keto reductase family 1 member C3 | / | 0.454 | |
| 4g2w | NI0 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.454 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.454 | |
| 4iwy | ADP | Ribosomal protein S6--L-glutamate ligase | / | 0.454 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.454 | |
| 5kf2 | COA | Predicted acetyltransferase | / | 0.454 | |
| 1ao8 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1hfp | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1je1 | GMP | Purine nucleoside phosphorylase | / | 0.453 | |
| 1pr6 | XYA | Purine nucleoside phosphorylase DeoD-type | / | 0.453 | |
| 1pwm | FID | Aldose reductase | 1.1.1.21 | 0.453 | |
| 1rx5 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1t4c | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.453 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.453 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 2b1z | 17M | Estrogen receptor | / | 0.453 | |
| 2bel | CBO | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.453 | |
| 2g1a | 5HG | Class B acid phosphatase | 3.1.3.2 | 0.453 | |
| 2j7c | IDE | Beta-glucosidase A | 3.2.1.21 | 0.453 | |
| 2ofv | 242 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.453 | |
| 2vf0 | F89 | Thymidylate synthase | / | 0.453 | |
| 3c1x | CKK | Hepatocyte growth factor receptor | 2.7.10.1 | 0.453 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.453 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.453 | |
| 3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.453 | |
| 3ntg | D72 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.453 | |
| 3o76 | GTB | Glutathione S-transferase P 1 | 2.5.1.18 | 0.453 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 3qly | 55V | Uncharacterized protein | / | 0.453 | |
| 4djx | 0KQ | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4elf | 35I | Dihydrofolate reductase | / | 0.453 | |
| 4lsa | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.453 | |
| 4lwx | MU2 | Ribosome inactivating protein | / | 0.453 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.453 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.452 | |
| 1ju6 | LYA | Thymidylate synthase | 2.1.1.45 | 0.452 | |
| 1ove | 358 | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 1qy2 | IPZ | Major urinary protein 1 | / | 0.452 | |
| 1rfq | LAR | Actin, alpha skeletal muscle | / | 0.452 | |
| 1sui | SAH | Caffeoyl-CoA O-methyltransferase | 2.1.1.104 | 0.452 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.452 | |
| 1v79 | FR7 | Adenosine deaminase | 3.5.4.4 | 0.452 | |
| 1vhn | FMN | tRNA-dihydrouridine synthase | / | 0.452 | |
| 1xi2 | CB1 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.452 | |
| 2ati | IHU | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.452 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.452 | |
| 2e98 | B29 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.452 | |
| 2r7n | ADP | 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase | / | 0.452 | |
| 3bjc | WAN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.452 | |
| 3clb | TMQ | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.452 | |
| 3d4b | DZD | NAD-dependent protein deacetylase | / | 0.452 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.452 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.452 | |
| 3gwn | FAD | Probable FAD-linked sulfhydryl oxidase R596 | 1.8.3.2 | 0.452 | |
| 3gwu | SRE | Na(+):neurotransmitter symporter (Snf family) | / | 0.452 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.452 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.452 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.452 | |
| 3n10 | CMP | Adenylate cyclase 2 | / | 0.452 | |
| 3n5v | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.452 | |
| 3oia | A31 | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.452 | |
| 3q2m | CKI | Spectinomycin phosphotransferase | / | 0.452 | |
| 3qzy | FAD | FAD-linked sulfhydryl oxidase | / | 0.452 | |
| 3rj0 | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.452 | |
| 3tqb | FOL | Dihydrofolate reductase | / | 0.452 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.452 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.452 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.452 | |
| 3zhq | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.452 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.452 | |
| 4dkb | DUN | Deoxyuridine triphosphatase, putative | / | 0.452 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.452 | |
| 4i42 | 1HA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.452 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.452 | |
| 4j26 | EST | Estrogen receptor beta | / | 0.452 | |
| 4jq1 | NPS | Aldo-keto reductase family 1 member C2 | / | 0.452 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.452 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.451 | |
| 1cqs | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.451 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1e7a | PFL | Serum albumin | / | 0.451 | |
| 1exa | 394 | Retinoic acid receptor gamma | / | 0.451 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.451 | |
| 1m79 | MQ1 | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.451 | |
| 1rvv | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.451 | |
| 1u3s | 797 | Estrogen receptor beta | / | 0.451 | |
| 2ay9 | 5PV | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.451 | |
| 2d0k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.451 | |
| 2j7y | E3O | Estrogen receptor beta | / | 0.451 | |
| 2p15 | EZT | Estrogen receptor | / | 0.451 | |
| 2xnn | 430 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.451 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.451 | |
| 3a25 | SAM | tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase | / | 0.451 | |
| 3bmn | AX3 | Pteridine reductase | / | 0.451 | |
| 3c4a | FAD | Protodeoxyviolaceinate monooxygenase | 1 | 0.451 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.451 | |
| 3fzt | 4JZ | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.451 | |
| 3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.451 | |
| 3jwc | EKB | Dihydrofolate reductase | / | 0.451 | |
| 3u3o | 3QV | Sulfotransferase 1A1 | 2.8.2.1 | 0.451 | |
| 3w0t | HPU | Lactoylglutathione lyase | 4.4.1.5 | 0.451 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.451 | |
| 3zrr | PXG | Serine-pyruvate aminotransferase (AgxT) | / | 0.451 | |
| 4au7 | SAH | Histone-lysine N-methyltransferase KMT5C | 2.1.1.43 | 0.451 | |
| 4fgj | 1PQ | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.451 | |
| 4g8z | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4gtt | 7TQ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.451 | |
| 4h1j | 0YH | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.451 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 5agy | GTB | Tau class glutathione S-transferase | / | 0.451 | |
| 2ycy | P32 | Beta-1 adrenergic receptor | / | 0.451 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.450 | |
| 1fr8 | GDU | Beta-1,4-galactosyltransferase 1 | / | 0.450 | |
| 1jx0 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.450 | |
| 1rxj | BNI | Streptavidin | / | 0.450 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.450 | |
| 1typ | NAP | Trypanothione reductase | 1.8.1.12 | 0.450 | |
| 1ux0 | THU | Cytidine deaminase | 3.5.4.5 | 0.450 | |
| 1zky | 689 | Estrogen receptor | / | 0.450 | |
| 2d3a | ADP | Glutamine synthetase root isozyme 3 | 6.3.1.2 | 0.450 | |
| 2e48 | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.450 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2jdv | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
| 2pdl | TOL | Aldose reductase | 1.1.1.21 | 0.450 | |
| 2v3h | I25 | Prothrombin | 3.4.21.5 | 0.450 | |
| 2vdy | HCY | Corticosteroid-binding globulin | / | 0.450 | |
| 2xke | WI2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.450 | |
| 2xlr | NAP | Putative flavin-containing monooxygenase | / | 0.450 | |
| 3ar5 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.450 | |
| 3c3b | CDP | Phosphoglycerate kinase 1 | 2.7.2.3 | 0.450 | |
| 3cxh | SMA | Cytochrome b | / | 0.450 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.450 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.450 | |
| 3new | 3NE | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.450 | |
| 3szf | DCQ | Sulfide-quinone reductase | / | 0.450 | |
| 4ixc | 1JD | Glucokinase | 2.7.1.2 | 0.450 | |
| 4ixe | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4jq2 | SUZ | Aldo-keto reductase family 1 member C2 | / | 0.450 | |
| 4p5f | AR6 | Inosine-uridine nucleoside N-ribohydrolase | / | 0.450 | |
| 4rbs | 0RV | Metallo-beta-lactamase type 2 | / | 0.450 | |
| 4ug7 | 1EV | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.450 | |
| 4xoq | F42 | Coenzyme F420:L-glutamate ligase | / | 0.450 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.450 | |
| 1al7 | HST | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.449 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1pua | COA | HAT A1 | / | 0.449 | |
| 1q6s | 214 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.449 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.449 | |
| 1uhh | CZP | Aequorin-2 | / | 0.449 | |
| 1xpc | AIT | Estrogen receptor | / | 0.449 | |
| 1ycg | FMN | Nitric oxide reductase | 1 | 0.449 | |
| 2c3u | 2TP | Pyruvate synthase | / | 0.449 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.449 | |
| 3c10 | TSN | Histone deacetylase 7 | 3.5.1.98 | 0.449 | |
| 3g6z | A7T | Renin | 3.4.23.15 | 0.449 | |
| 3gc4 | AAQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.449 | |
| 3hxb | BD5 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.449 | |
| 3lal | KRV | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 3p6p | A6B | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 3pah | XDE | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.449 | |
| 3qlr | QLR | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.449 | |
| 3zec | ANP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.449 | |
| 4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.449 | |
| 4bfp | SWY | Tankyrase-2 | 2.4.2.30 | 0.449 | |
| 4gkh | 0J9 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.449 | |
| 4gr9 | 372 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.449 | |
| 4htx | 19F | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.449 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.449 | |
| 4k4e | K4E | Tankyrase-1 | 2.4.2.30 | 0.449 | |
| 4kg1 | PCG | Diguanylate cyclase | / | 0.449 | |
| 4m8e | 29V | Retinoic acid receptor RXR-alpha | / | 0.449 | |
| 4qa1 | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.449 | |
| 4tzk | 641 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 5dq8 | FLF | Transcriptional enhancer factor TEF-4 | / | 0.449 | |
| 5ej6 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.449 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.449 | |
| 1k8z | IAG | Tryptophan synthase alpha chain | / | 0.448 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.448 | |
| 1s36 | CEI | Obelin | / | 0.448 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.448 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.448 | |
| 1uxu | NAP | NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase | / | 0.448 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 2bla | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.448 | |
| 2bn4 | FAD | NADPH--cytochrome P450 reductase | / | 0.448 | |
| 2e95 | B75 | Geranylgeranyl pyrophosphate synthase | / | 0.448 | |
| 2hm9 | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 2i4t | UA2 | Purine nucleoside phosphorylase, putative | / | 0.448 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 2q3e | UPG | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.448 | |
| 2toh | HBI | Tyrosine 3-monooxygenase | 1.14.16.2 | 0.448 | |
| 2w3v | TOP | Dihydrofolate reductase | / | 0.448 | |
| 2xlt | NA0 | Putative flavin-containing monooxygenase | / | 0.448 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.448 | |
| 3d77 | NBB | Pheromone-binding protein ASP1 | / | 0.448 | |
| 3da2 | 4MD | Carbonic anhydrase 13 | 4.2.1.1 | 0.448 | |
| 3ews | ADP | ATP-dependent RNA helicase DDX19B | 3.6.4.13 | 0.448 | |
| 3jt8 | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.448 | |
| 3lq2 | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.448 | |
| 3occ | DIH | Purine nucleoside phosphorylase DeoD-type | / | 0.448 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 3sso | SAH | Mycinamicin VI 2''-O-methyltransferase | / | 0.448 | |
| 3x2f | NAI | Adenosylhomocysteinase | / | 0.448 | |
| 4boe | CLR | Japanin | / | 0.448 | |
| 4cjw | CBJ | Integrase | / | 0.448 | |
| 4g31 | 0WH | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.448 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4gsy | 0Y5 | Thymidylate kinase | / | 0.448 | |
| 4iah | 1DX | Alr2278 protein | / | 0.448 | |
| 4imu | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.448 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.448 | |
| 4klr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.448 | |
| 4l7j | 1W2 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4nx6 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.448 | |
| 5d1b | TSN | Histone deacetylase 8 | 3.5.1.98 | 0.448 | |
| 5ej4 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.448 | |
| 5kf2 | ACO | Predicted acetyltransferase | / | 0.448 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.448 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.447 | |
| 1d7o | TCL | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.447 | |
| 1dxr | MST | Reaction center protein L chain | / | 0.447 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.447 | |
| 1l0l | FMX | Cytochrome b | / | 0.447 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.447 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.447 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1tkz | H16 | Gag-Pol polyprotein | 2.7.7.49 | 0.447 | |
| 1u1c | BAU | Uridine phosphorylase | 2.4.2.3 | 0.447 | |
| 1xls | REA | Retinoic acid receptor RXR-alpha | / | 0.447 | |
| 1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.447 | |
| 1zz1 | SHH | Histone deacetylase-like amidohydrolase | 3.5.1 | 0.447 | |
| 2g44 | T3O | Estrogen receptor | / | 0.447 | |
| 2giu | FBR | Estrogen receptor beta | / | 0.447 | |
| 2i0v | 6C3 | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.447 | |
| 2q15 | 3MR | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 2v95 | HCY | Corticosteroid-binding globulin | / | 0.447 | |
| 2ylo | TES | Androgen receptor | / | 0.447 | |
| 2z7g | EH9 | Adenosine deaminase | 3.5.4.4 | 0.447 | |
| 3arv | SAU | Chitinase A | / | 0.447 | |
| 3b7d | CNI | Glutamate receptor 2 | / | 0.447 | |
| 3b9o | FMN | Alkane monoxygenase | / | 0.447 | |
| 3bsy | ACO | UDP-N-acetylbacillosamine N-acetyltransferase | 2.3.1.203 | 0.447 | |
| 3c34 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.447 | |
| 3cgy | RDC | Virulence sensor histidine kinase PhoQ | 2.7.13.3 | 0.447 | |
| 3n33 | AES | Beta-peptidyl aminopeptidase BapA | / | 0.447 | |
| 3n3a | FMN | Protein NrdI | / | 0.447 | |
| 3n87 | N87 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.447 | |
| 3nhk | VAP | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.447 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.447 | |
| 3qlw | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3qpp | PFW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 3t0k | DCQ | Sulfide-quinone reductase | / | 0.447 | |
| 3tdk | UPG | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.447 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 4b8m | VX6 | Aurora kinase B-A | 2.7.11.1 | 0.447 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 4cx4 | HW9 | Nitric oxide synthase, brain | 1.14.13.39 | 0.447 | |
| 4elb | 34S | Dihydrofolate reductase | / | 0.447 | |
| 4h38 | 0YX | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.447 | |
| 4jtr | IBP | Aldo-keto reductase family 1 member C2 | / | 0.447 | |
| 4jvl | EST | Estrogen sulfotransferase | 2.8.2.4 | 0.447 | |
| 4k5g | Q13 | Nitric oxide synthase, brain | 1.14.13.39 | 0.447 | |
| 4m8h | R4M | Retinoic acid receptor RXR-alpha | / | 0.447 | |
| 4mm9 | FVX | Na(+):neurotransmitter symporter (Snf family) | / | 0.447 | |
| 4mrx | CZH | Obelin | / | 0.447 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.447 | |
| 4ttj | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.447 | |
| 4ubv | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.447 | |
| 4yao | 2AM | NADPH--cytochrome P450 reductase | / | 0.447 | |
| 4uhr | NGI | Adenosine receptor A2a | / | 0.447 | |
| 1fm9 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.446 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.446 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.446 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.446 | |
| 1sj0 | E4D | Estrogen receptor | / | 0.446 | |
| 1std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.446 | |
| 1t9c | 1SM | Acetolactate synthase catalytic subunit, mitochondrial | 2.2.1.6 | 0.446 | |
| 1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.446 | |
| 1uhj | CZB | Aequorin-2 | / | 0.446 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.446 | |
| 1z89 | 62P | Aldose reductase | 1.1.1.21 | 0.446 | |
| 2fai | 459 | Estrogen receptor | / | 0.446 | |
| 2i8c | ADP | D-alanine--D-alanine ligase | / | 0.446 | |
| 2pun | ACP | Methylthioribose kinase | 2.7.1.100 | 0.446 | |
| 2x9g | LYA | Pteridine reductase | / | 0.446 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.446 | |
| 2zce | PYL | Pyrrolysine--tRNA ligase | / | 0.446 | |
| 3d75 | NBB | Pheromone-binding protein ASP1 | / | 0.446 | |
| 3dko | IHZ | Ephrin type-A receptor 7 | 2.7.10.1 | 0.446 | |
| 3ds6 | A17 | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 3hf6 | LX0 | Tryptophan 5-hydroxylase 1 | 1.14.16.4 | 0.446 | |
| 3hqd | ANP | Kinesin-like protein KIF11 | / | 0.446 | |
| 3nwl | NDP | Catalase | 1.11.1.6 | 0.446 | |
| 3nxr | D2D | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3pnf | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.446 | |
| 3uwl | FOZ | Thymidylate synthase | / | 0.446 | |
| 4agw | NG7 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.446 | |
| 4cav | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.446 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.446 | |
| 4cx5 | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.446 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.446 | |
| 4elb | 34R | Dihydrofolate reductase | / | 0.446 | |
| 4fu0 | ADP | D-alanine--D-alanine ligase | / | 0.446 | |
| 4g34 | 924 | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.446 | |
| 4kyh | ZST | Lactoylglutathione lyase | 4.4.1.5 | 0.446 | |
| 4msg | 2C6 | Tankyrase-1 | 2.4.2.30 | 0.446 | |
| 4rtb | SAM | Putative thiazole biosynthesis protein ThiH | / | 0.446 | |
| 4s1i | PLP | Pyridoxal kinase, putative | / | 0.446 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.446 | |
| 6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.446 | |
| 1aqx | GTD | Glutathione S-transferase P | 2.5.1.18 | 0.445 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1kdm | DHT | Sex hormone-binding globulin | / | 0.445 | |
| 1mj3 | HXC | Enoyl-CoA hydratase, mitochondrial | 4.2.1.17 | 0.445 | |
| 1q63 | AIQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.445 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1sl9 | CZH | Obelin | / | 0.445 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.445 | |
| 1wdk | ACO | 3-ketoacyl-CoA thiolase | / | 0.445 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.445 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.445 | |
| 2bfa | CB3 | Pteridine reductase 1 | 1.5.1.33 | 0.445 | |
| 2bil | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 2chw | 039 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 2ilt | NN1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 2jdd | ACO | Probable acetyltransferase | / | 0.445 | |
| 2nsd | 4PI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 2rcw | AAI | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.445 | |
| 2w8y | 486 | Progesterone receptor | / | 0.445 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.445 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.445 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.445 | |
| 3bhr | THG | Thymidylate synthase | / | 0.445 | |
| 3d2d | REN | Reticuline oxidase | 1.21.3.3 | 0.445 | |
| 3d3e | D3E | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 3fgo | ACP | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.445 | |
| 3gki | CLR | Niemann-Pick C1 protein | / | 0.445 | |
| 3hy4 | N5G | 5-formyltetrahydrofolate cyclo-ligase | 6.3.3.2 | 0.445 | |
| 3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.445 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.445 | |
| 3qp8 | HL0 | Transcriptional activator, LuxR/UhpA family of regulators | / | 0.445 | |
| 3qri | 919 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.445 | |
| 3qwi | CUE | 17beta-hydroxysteroid dehydrogenase | / | 0.445 | |
| 3rth | RTH | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3u8f | FGM | Ribosome inactivating protein | / | 0.445 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.445 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.445 | |
| 4a99 | MIY | TetX family tetracycline inactivation enzyme | / | 0.445 | |
| 4bb2 | STR | Corticosteroid-binding globulin | / | 0.445 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 4c8b | 0LI | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.445 | |
| 4gg9 | 0WW | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.445 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.445 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.445 | |
| 4lga | A2O | Abscisic acid receptor PYL2 | / | 0.445 | |
| 4oma | LCS | Methionine gamma-lyase | / | 0.445 | |
| 1a8t | 061 | Metallo-beta-lactamase type 2 | / | 0.444 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.444 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.444 | |
| 1i05 | LTL | Major urinary protein 6 | / | 0.444 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 1rb2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1rti | HEF | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 1u1j | C2F | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 1 | 2.1.1.14 | 0.444 | |
| 1u9e | 397 | Estrogen receptor beta | / | 0.444 | |
| 1yy4 | 4NA | Estrogen receptor beta | / | 0.444 | |
| 1zzq | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.444 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.444 | |
| 2oiq | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.444 | |
| 2piw | DHT | Androgen receptor | / | 0.444 | |
| 2w3a | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 2xk6 | EQH | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.444 | |
| 2ycw | CAU | Beta-1 adrenergic receptor | / | 0.444 | |
| 2yiu | SMA | Cytochrome b | / | 0.444 | |
| 3bzu | A21 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.444 | |
| 3eei | MTM | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | / | 0.444 | |
| 3ge7 | AFQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.444 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.444 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3pnf | 8BX | Nitric oxide synthase, brain | 1.14.13.39 | 0.444 | |
| 3ql3 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 4ajw | VWN | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 2.7.1.153 | 0.444 | |
| 4bdr | KAI | Glutamate receptor ionotropic, kainate 2 | / | 0.444 | |
| 4c2z | 646 | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.444 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4h4o | 506 | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.444 | |
| 1ah3 | TOL | Aldose reductase | 1.1.1.21 | 0.443 | |
| 1df7 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1dg5 | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1dna | CB3 | Thymidylate synthase | / | 0.443 | |
| 1g60 | SAM | Modification methylase MboII | 2.1.1.72 | 0.443 | |
| 1ia1 | TQ3 | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1n4s | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.443 | |
| 1nc1 | MTH | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | 3.2.2.9 | 0.443 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.443 | |
| 1pke | 2FD | Purine nucleoside phosphorylase DeoD-type | / | 0.443 | |
| 1qv1 | CZH | Obelin | / | 0.443 | |
| 1r00 | SAH | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.443 | |
| 1r35 | H4B | Nitric oxide synthase, inducible | 1.14.13.39 | 0.443 | |
| 1xdu | SFG | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.443 | |
| 1y6r | MTM | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | 3.2.2.9 | 0.443 | |
| 1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.443 | |
| 2b00 | GCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.443 | |
| 2bu5 | TF1 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.443 | |
| 2gpv | OHT | Estrogen-related receptor gamma | / | 0.443 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.443 | |
| 2qei | CXX | Na(+):neurotransmitter symporter (Snf family) | / | 0.443 | |
| 2tsc | CB3 | Thymidylate synthase | / | 0.443 | |
| 2uxh | QUE | HTH-type transcriptional regulator TtgR | / | 0.443 | |
| 2ykc | YKC | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 3bjh | NBB | Odorant binding protein ASP1 | / | 0.443 | |
| 3c36 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.443 | |
| 3cz0 | 9OD | Pheromone-binding protein ASP1 | / | 0.443 | |
| 3fko | FKO | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3gg2 | UGA | Sugar dehydrogenase, UDP-glucose/GDP-mannose dehydrogenase family | / | 0.443 | |
| 3p0e | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.443 | |
| 3pdt | ADP | Myosin heavy chain kinase A | 2.7.11.7 | 0.443 | |
| 3phc | IM5 | Purine nucleoside phosphorylase | / | 0.443 | |
| 3rtm | RTM | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.443 | |
| 4ajg | F07 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4hyf | 1AK | Tankyrase-2 | 2.4.2.30 | 0.443 | |
| 4isg | 1FY | Glucokinase | 2.7.1.2 | 0.443 | |
| 4kvg | GTP | Ras-related protein Rap-1A | / | 0.443 | |
| 4man | 1Y1 | Apoptosis regulator Bcl-2 | / | 0.443 | |
| 4mfb | 29T | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 4myq | 19T | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.443 | |
| 4n1g | CEI | Obelin | / | 0.443 | |
| 4nqg | CZH | Mitrocomin | / | 0.443 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.443 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.443 | |
| 5doz | NDP | JamJ | / | 0.443 | |
| 1c1b | GCA | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.442 | |
| 1hlk | 113 | Metallo-beta-lactamase type 2 | / | 0.442 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.442 | |
| 1m78 | CLZ | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1m9k | 7NI | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.442 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.442 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.442 | |
| 1ra2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1wet | GUN | HTH-type transcriptional repressor PurR | / | 0.442 | |
| 1zpr | CB3 | Thymidylate synthase | / | 0.442 | |
| 1zzl | TZY | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 2a4n | COA | Aac(6')-Ii protein | / | 0.442 | |
| 2pui | ADP | Methylthioribose kinase | 2.7.1.100 | 0.442 | |
| 2wks | CB6 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.442 | |
| 2xlp | NAP | Putative flavin-containing monooxygenase | / | 0.442 | |
| 3acy | 702 | Dehydrosqualene synthase | / | 0.442 | |
| 3d78 | NBB | Pheromone-binding protein ASP1 | / | 0.442 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 3gb4 | D3M | DdmC | / | 0.442 | |
| 3i6r | J5Z | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.442 | |
| 3n62 | XFJ | Nitric oxide synthase, brain | 1.14.13.39 | 0.442 | |
| 3nlw | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.442 | |
| 3ou6 | SAM | SAM-dependent methyltransferase | / | 0.442 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.442 | |
| 3png | 8CX | Nitric oxide synthase, brain | 1.14.13.39 | 0.442 | |
| 3ql6 | NIM | Lactoperoxidase | 1.11.1.7 | 0.442 | |
| 3qlz | QLZ | Uncharacterized protein | / | 0.442 | |
| 3vjc | ZGA | Squalene synthase | 2.5.1.21 | 0.442 | |
| 3vo2 | FAD | Ferredoxin--NADP reductase | / | 0.442 | |
| 3zc3 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.442 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 4ag9 | COA | Glucosamine 6-phosphate N-acetyltransferase | / | 0.442 | |
| 4djv | 0KM | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4eux | HW1 | Nitric oxide synthase, brain | 1.14.13.39 | 0.442 | |
| 4fj2 | QSO | 17beta-hydroxysteroid dehydrogenase | / | 0.442 | |
| 4hfn | CIY | 2-alkenal reductase (NADP(+)-dependent) | / | 0.442 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
| 4nwi | CTN | 7-methylguanosine phosphate-specific 5'-nucleotidase | / | 0.442 | |
| 4oe4 | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.442 | |
| 4rrh | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.442 | |
| 4uof | DAT | Nucleoside diphosphate kinase | / | 0.442 | |
| 5ahk | FAD | Acetolactate synthase II, large subunit | / | 0.442 | |
| 5gcn | COA | HAT A1 | / | 0.442 | |
| 1f28 | F89 | Thymidylate synthase | 2.1.1.45 | 0.441 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.441 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.441 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
| 1lhu | EST | Sex hormone-binding globulin | / | 0.441 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 1tkt | H12 | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 1tl3 | H20 | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 1w2d | ADP | Inositol-trisphosphate 3-kinase A | 2.7.1.127 | 0.441 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 2e41 | BTX | 235aa long hypothetical biotin--[acetyl-CoA-carboxylase] ligase | / | 0.441 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 2gsq | GBI | Glutathione S-transferase | 2.5.1.18 | 0.441 | |
| 2iut | AGS | DNA translocase FtsK | / | 0.441 | |
| 2qk8 | MTX | Dihydrofolate reductase | / | 0.441 | |
| 2za0 | MGI | Lactoylglutathione lyase | 4.4.1.5 | 0.441 | |
| 3aba | FLI | Cytochrome P450 | / | 0.441 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.441 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.441 | |
| 3c1o | NAP | Eugenol synthase | / | 0.441 | |
| 3c4h | DRL | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.441 | |
| 3caq | NDP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 3gan | SVR | Protein RDM1 | / | 0.441 | |
| 3ght | LDT | Aldose reductase | 1.1.1.21 | 0.441 | |
| 3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.441 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.441 | |
| 3qbw | ADP | Anhydro-N-acetylmuramic acid kinase | / | 0.441 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.441 | |
| 3rl4 | 5GP | Metallophosphoesterase MPPED2 | 3.1 | 0.441 | |
| 3sa2 | 7DR | Dihydrofolate reductase | / | 0.441 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.441 | |
| 4bqu | CLR | Japanin | / | 0.441 | |
| 4ise | 1FW | Glucokinase | 2.7.1.2 | 0.441 | |
| 4iyg | 1HU | Strictosidine synthase | 4.3.3.2 | 0.441 | |
| 4k4j | 1O8 | Retinoic acid receptor RXR-alpha | / | 0.441 | |
| 4kw5 | 1W6 | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.441 | |
| 4nx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4ubt | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.441 | |
| 5bn3 | ADP | V-type ATP synthase alpha chain | / | 0.441 | |
| 5bn3 | ADP | NEQ263 | / | 0.441 | |
| 5jr3 | 4MU | Carminomycin 4-O-methyltransferase DnrK | 2.1.1.292 | 0.441 | |
| 1dlj | UGA | UDP-glucose 6-dehydrogenase | / | 0.440 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.440 | |
| 1lb9 | DNQ | Glutamate receptor 2 | / | 0.440 | |
| 1mc5 | AHE | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.440 | |
| 1n5v | NOM | ActVA 6 protein | / | 0.440 | |
| 1q4w | DQU | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.440 | |
| 1rs6 | DP2 | Nitric oxide synthase, brain | 1.14.13.39 | 0.440 | |
| 1z2c | GNP | Rho-related GTP-binding protein RhoC | / | 0.440 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 2v57 | PRL | TetR family transcriptional regulator | / | 0.440 | |
| 2vbv | FMN | Riboflavin kinase | 2.7.1.161 | 0.440 | |
| 2vqj | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.440 | |
| 2xkf | BX1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.440 | |
| 2yat | EEU | Estrogen receptor | / | 0.440 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.440 | |
| 3dtc | VIN | Mitogen-activated protein kinase kinase kinase 9 | 2.7.11.25 | 0.440 | |
| 3hpq | AP5 | Adenylate kinase | / | 0.440 | |
| 3i8a | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3lmh | ADP | Myosin heavy chain kinase A | 2.7.11.7 | 0.440 | |
| 3n5x | XFK | Nitric oxide synthase, brain | 1.14.13.39 | 0.440 | |
| 3ntd | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.440 | |
| 3qlx | QLR | Uncharacterized protein | / | 0.440 | |
| 3rqm | X2E | Nitric oxide synthase, brain | 1.14.13.39 | 0.440 | |
| 3sgl | SAM | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.440 | |
| 3t9i | 3T9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4bfs | ZVS | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4bmz | MTA | Aminodeoxyfutalosine nucleosidase | / | 0.440 | |
| 4da8 | BG2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.440 | |
| 4dp3 | MMV | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.440 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.440 | |
| 4ft4 | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.440 | |
| 4ivq | I43 | Thymidine kinase | / | 0.440 | |
| 4ksp | 1SU | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.440 | |
| 4rh1 | 0TT | Spore photoproduct lyase | / | 0.440 | |
| 4ydq | HFG | Proline--tRNA ligase | 6.1.1.15 | 0.440 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.440 | |
| 2rh1 | CAU | Beta-2 adrenergic receptor | / | 0.440 |