sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4ixd | 1HV | Integrin alpha-L |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4ixd | 1HV | Integrin alpha-L | / | 1.000 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.610 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.572 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.565 | |
| 4rh1 | 0TT | Spore photoproduct lyase | / | 0.540 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.532 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.522 | |
| 4tzt | 468 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.518 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.517 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.516 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.515 | |
| 1efa | NPF | Lactose operon repressor | / | 0.510 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.509 | |
| 1n71 | COA | Aac(6')-Ii protein | / | 0.509 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.509 | |
| 2vss | ACO | Hydroxycinnamoyl-CoA hydratase-lyase | 4.1.2.41 | 0.507 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.506 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.506 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.505 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.504 | |
| 3up0 | D7S | aceDAF-12 | / | 0.504 | |
| 1hk4 | T44 | Serum albumin | / | 0.502 | |
| 1m78 | CLZ | Dihydrofolate reductase | 1.5.1.3 | 0.502 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.502 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.501 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.501 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.501 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.501 | |
| 5cb3 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.500 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.499 | |
| 3cse | N22 | Uncharacterized protein | / | 0.498 | |
| 3qlr | QLR | Dihydrofolate reductase | 1.5.1.3 | 0.498 | |
| 3sh2 | 5DR | Dihydrofolate reductase | 1.5.1.3 | 0.498 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.497 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.496 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.495 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.495 | |
| 1oj4 | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.494 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.494 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.494 | |
| 3up3 | XCA | aceDAF-12 | / | 0.494 | |
| 3x04 | GNP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.494 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.493 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.493 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.493 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.493 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.493 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.492 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.492 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.492 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.491 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.490 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.490 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.490 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.490 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.489 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.489 | |
| 2lbv | EB4 | Extracellular fatty acid-binding protein | / | 0.489 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.489 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.489 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.489 | |
| 4xrb | NDP | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.489 | |
| 1xmm | M7G | m7GpppX diphosphatase | 3.6.1.59 | 0.488 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.488 | |
| 4at4 | T6E | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.488 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.488 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.487 | |
| 3p9t | TCL | Repressor | / | 0.487 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.487 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.487 | |
| 2bik | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.486 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.486 | |
| 3gie | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.486 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.486 | |
| 3s41 | S41 | Glucokinase | 2.7.1.2 | 0.486 | |
| 4b1i | A8P | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.486 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.486 | |
| 4o4f | ATP | Kinase | / | 0.486 | |
| 2qk8 | MTX | Dihydrofolate reductase | / | 0.485 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.485 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.485 | |
| 1a4i | NDP | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.484 | |
| 3ar5 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.484 | |
| 4qx5 | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.484 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.483 | |
| 1zga | HMK | Isoflavone 4'-O-methyltransferase | / | 0.483 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.483 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.483 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.483 | |
| 4ie0 | PD2 | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.483 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.483 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.483 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.482 | |
| 1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.482 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.482 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.482 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.482 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.482 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.482 | |
| 3tky | N7I | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.482 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.482 | |
| 4tzk | 641 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.482 | |
| 4u0k | 744 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.482 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.481 | |
| 3fra | I2H | Dihydrofolate reductase | 1.5.1.3 | 0.481 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.481 | |
| 4l9q | 9TP | Serum albumin | / | 0.481 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.481 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.481 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.481 | |
| 1gs3 | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.480 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.480 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.480 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.480 | |
| 2io6 | 330 | Wee1-like protein kinase | 2.7.10.2 | 0.480 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.480 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.480 | |
| 3dg8 | RJ6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.480 | |
| 3zlm | ANP | Adenosine monophosphate-protein transferase NmFic | 2.7.7.n1 | 0.480 | |
| 4azw | ATP | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.480 | |
| 4tx9 | AMZ | Phosphoribosyl isomerase A | / | 0.480 | |
| 1mzn | BM6 | Retinoic acid receptor RXR-alpha | / | 0.479 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.479 | |
| 2b37 | 8PS | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.479 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.479 | |
| 2pl0 | STI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.479 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.479 | |
| 3keq | NAD | Redox-sensing transcriptional repressor Rex | / | 0.479 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.479 | |
| 5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.479 | |
| 2bxm | IMN | Serum albumin | / | 0.478 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.478 | |
| 3jwc | EKB | Dihydrofolate reductase | / | 0.478 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.478 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.477 | |
| 1dli | UDX | UDP-glucose 6-dehydrogenase | / | 0.477 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.477 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.477 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.477 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.477 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.477 | |
| 3hbb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.477 | |
| 3hz1 | 42C | Heat shock protein HSP 90-alpha | / | 0.477 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.477 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.477 | |
| 4awt | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.477 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.477 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.477 | |
| 1jom | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.476 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.476 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.476 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.476 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.476 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.476 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.476 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.476 | |
| 4ixe | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.476 | |
| 4kwh | NAP | Reductase homolog | / | 0.476 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.476 | |
| 1vrq | FON | Subunit alpha of sarocosine oxidase | / | 0.475 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.475 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.475 | |
| 2gou | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.475 | |
| 2oiq | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.475 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.475 | |
| 2yvw | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.475 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.475 | |
| 3q2m | CKI | Spectinomycin phosphotransferase | / | 0.475 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.474 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.474 | |
| 2gqa | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.474 | |
| 2rdn | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.474 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.474 | |
| 3bsy | ACO | UDP-N-acetylbacillosamine N-acetyltransferase | 2.3.1.203 | 0.474 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.474 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.474 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.474 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.474 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.474 | |
| 4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.474 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.474 | |
| 1f8g | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.473 | |
| 1osv | CHC | Bile acid receptor | / | 0.473 | |
| 1upa | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.473 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.473 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.473 | |
| 3ele | PLP | Aminotransferase | / | 0.473 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.473 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.473 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.473 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.473 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.473 | |
| 4trj | 665 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.473 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.473 | |
| 1e2n | RCA | Thymidine kinase | / | 0.472 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.472 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.472 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.472 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.472 | |
| 2fpc | SCG | Strictosidine synthase | 4.3.3.2 | 0.472 | |
| 2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.472 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.472 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.472 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.472 | |
| 3thr | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.472 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.472 | |
| 4eil | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.472 | |
| 4ej1 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 4yx6 | FMN | Omega-3 polyunsaturated fatty acid synthase subunit PfaD | / | 0.472 | |
| 1f5f | DHT | Sex hormone-binding globulin | / | 0.471 | |
| 1gpe | FAD | Glucose oxidase | 1.1.3.4 | 0.471 | |
| 1l8q | ADP | Chromosomal replication initiator protein DnaA | / | 0.471 | |
| 1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.471 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.471 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.471 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.471 | |
| 2a4n | COA | Aac(6')-Ii protein | / | 0.471 | |
| 3neg | PYV | Abscisic acid receptor PYL1 | / | 0.471 | |
| 3reo | EUG | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.471 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.471 | |
| 3vg9 | ZMA | Adenosine receptor A2a | / | 0.471 | |
| 4ckc | SAH | mRNA-capping enzyme catalytic subunit | 2.1.1.56 | 0.471 | |
| 4kug | NAD | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.471 | |
| 4m8e | 29V | Retinoic acid receptor RXR-alpha | / | 0.471 | |
| 4wuo | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.471 | |
| 4xym | COA | Acyl-CoA synthetase (NDP forming) | / | 0.471 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.470 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.470 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.470 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.470 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.470 | |
| 4fr1 | 0V2 | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.470 | |
| 4h6u | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.470 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.469 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.469 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.469 | |
| 2npn | SAM | Putative cobalamin synthesis related protein | / | 0.469 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.469 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.469 | |
| 2xkf | BX1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.469 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.469 | |
| 3jw5 | TOP | Dihydrofolate reductase | / | 0.469 | |
| 3lq2 | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.469 | |
| 3qlw | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.469 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.469 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.469 | |
| 4h6k | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.469 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.469 | |
| 4wh3 | ATP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.469 | |
| 7cat | NDP | Catalase | 1.11.1.6 | 0.469 | |
| 1d2s | DHT | Sex hormone-binding globulin | / | 0.468 | |
| 1i00 | D16 | Thymidylate synthase | 2.1.1.45 | 0.468 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.468 | |
| 2blc | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.468 | |
| 2xvw | 9NR | Serum albumin | / | 0.468 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.468 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.468 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.468 | |
| 3oap | REA | Retinoic acid receptor RXR-alpha | / | 0.468 | |
| 4pkw | GM6 | Lethal factor | 3.4.24.83 | 0.468 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.468 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 1kt3 | RTL | Retinol-binding protein 4 | / | 0.467 | |
| 1ne4 | RP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.467 | |
| 1qnf | HDF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.467 | |
| 2ji9 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.467 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.467 | |
| 3hz1 | 37D | Heat shock protein HSP 90-alpha | / | 0.467 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.467 | |
| 3zsh | 469 | Mitogen-activated protein kinase 14 | / | 0.467 | |
| 4oae | CLM | Uncharacterized protein | / | 0.467 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.467 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1eio | GCH | Gastrotropin | / | 0.466 | |
| 1mvc | BM6 | Retinoic acid receptor RXR-alpha | / | 0.466 | |
| 1o1v | TCH | Gastrotropin | / | 0.466 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.466 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.466 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.466 | |
| 1xls | REA | Retinoic acid receptor RXR-alpha | / | 0.466 | |
| 2b1z | 17M | Estrogen receptor | / | 0.466 | |
| 2c31 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.466 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.466 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.466 | |
| 2rab | NAD | Glutathione amide reductase | / | 0.466 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.466 | |
| 3d5q | T30 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.466 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.466 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.466 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.466 | |
| 4aws | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.466 | |
| 4b5o | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.466 | |
| 4c3y | FAD | 3-ketosteroid dehydrogenase | / | 0.466 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.466 | |
| 4gi4 | 0EX | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.466 | |
| 4iah | 1DX | Alr2278 protein | / | 0.466 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.466 | |
| 4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.466 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.466 | |
| 4u07 | ATP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.466 | |
| 5dn1 | AMZ | Phosphoribosyl isomerase A | 5.3.1.16 | 0.466 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.465 | |
| 1bzf | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 1hfp | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 1kw6 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.465 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.465 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.465 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.465 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.465 | |
| 2yat | EEU | Estrogen receptor | / | 0.465 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.465 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.465 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.465 | |
| 4eu4 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.465 | |
| 4xo7 | ASD | Aldo-keto reductase family 1 member C2 | / | 0.465 | |
| 1eir | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.464 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.464 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.464 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.464 | |
| 3e92 | G6A | Mitogen-activated protein kinase 14 | / | 0.464 | |
| 3fre | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.464 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.464 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.464 | |
| 3mje | NDP | AmphB | / | 0.464 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.464 | |
| 4ea1 | 3RX | Dehydrosqualene synthase | / | 0.464 | |
| 4je5 | PLP | Aromatic/aminoadipate aminotransferase 1 | 2.6.1.39 | 0.464 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.464 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.463 | |
| 1k74 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.463 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.463 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.463 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.463 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.463 | |
| 2ewa | SB2 | Mitogen-activated protein kinase 14 | / | 0.463 | |
| 2gqg | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.463 | |
| 2z2w | 770 | Wee1-like protein kinase | 2.7.10.2 | 0.463 | |
| 2zyn | BCD | Periplasmic binding protein | / | 0.463 | |
| 3b9l | AZZ | Serum albumin | / | 0.463 | |
| 3d75 | NBB | Pheromone-binding protein ASP1 | / | 0.463 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.463 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.463 | |
| 3qls | 55V | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 3t8x | T8X | T-cell surface glycoprotein CD1b | / | 0.463 | |
| 3wi2 | P98 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.463 | |
| 4az3 | S35 | Lysosomal protective protein | 3.4.16.5 | 0.463 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.462 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.462 | |
| 2b00 | GCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.462 | |
| 2blb | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.462 | |
| 2bxo | OPB | Serum albumin | / | 0.462 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.462 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.462 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.462 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.462 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.462 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.462 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.462 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.462 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.462 | |
| 4elb | 34S | Dihydrofolate reductase | / | 0.462 | |
| 4gh3 | 0EV | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.462 | |
| 4h6z | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.462 | |
| 4jbx | SK7 | Thymidine kinase | / | 0.462 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.462 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.462 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.462 | |
| 1i58 | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.461 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.461 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.461 | |
| 1r9o | FLP | Cytochrome P450 2C9 | / | 0.461 | |
| 1tlc | F89 | Thymidylate synthase | / | 0.461 | |
| 2cy2 | ACO | Probable acetyltransferase | / | 0.461 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.461 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.461 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.461 | |
| 2nsd | 4PI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.461 | |
| 3h1v | TK1 | Glucokinase | 2.7.1.2 | 0.461 | |
| 3pft | FMN | Flavin reductase | / | 0.461 | |
| 3sa1 | 6DR | Dihydrofolate reductase | / | 0.461 | |
| 3v2b | AR6 | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.461 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.461 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.461 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 4l1x | STR | Aldo-keto reductase family 1 member C2 | / | 0.461 | |
| 4lb2 | DM5 | Serum albumin | / | 0.461 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.461 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.460 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.460 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.460 | |
| 2bxq | IMN | Serum albumin | / | 0.460 | |
| 2ehu | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.460 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.460 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 2v3w | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.460 | |
| 2y88 | 2ER | Phosphoribosyl isomerase A | 5.3.1.16 | 0.460 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.460 | |
| 3fu9 | KIB | Laccase-1 | 1.10.3.2 | 0.460 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.460 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.460 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.460 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.460 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.460 | |
| 3qge | 26F | Genome polyprotein | 2.7.7.48 | 0.460 | |
| 3qly | 55V | Uncharacterized protein | / | 0.460 | |
| 3sgy | 06W | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 3uvv | REA | Retinoic acid receptor RXR-alpha | / | 0.460 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.460 | |
| 3zcn | ATP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.460 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.460 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.460 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.460 | |
| 4k4j | 1O8 | Retinoic acid receptor RXR-alpha | / | 0.460 | |
| 4qtn | NNR | Nicotinamide riboside transporter PnuC | / | 0.460 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.460 | |
| 4x5i | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 5i2h | AGI | O-methyltransferase family 2 | / | 0.460 | |
| 1lb9 | DNQ | Glutamate receptor 2 | / | 0.459 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1qkn | RAL | Estrogen receptor beta | / | 0.459 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.459 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.459 | |
| 2j0s | ANP | Eukaryotic initiation factor 4A-III | 3.6.4.13 | 0.459 | |
| 2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.459 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.459 | |
| 3htj | ET | EbrA repressor | / | 0.459 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.459 | |
| 3lu8 | IQX | Serum albumin | / | 0.459 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 4bkj | STI | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.459 | |
| 4kwi | 1TJ | Reductase homolog | / | 0.459 | |
| 4nm9 | FAD | Bifunctional protein PutA | / | 0.459 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.459 | |
| 4u7w | NDP | MxaA | / | 0.459 | |
| 5gcn | COA | HAT A1 | / | 0.459 | |
| 1gc5 | ADP | ADP-dependent glucokinase | 2.7.1.147 | 0.458 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.458 | |
| 1w83 | L11 | Mitogen-activated protein kinase 14 | / | 0.458 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.458 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.458 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.458 | |
| 2w3v | TOP | Dihydrofolate reductase | / | 0.458 | |
| 2wd8 | VGF | Pteridine reductase | / | 0.458 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 2z9d | FMN | FMN-dependent NADH-azoreductase | / | 0.458 | |
| 3dga | RJ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.458 | |
| 3ey4 | 352 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.458 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.458 | |
| 3lu7 | IPX | Serum albumin | / | 0.458 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.458 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.458 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.458 | |
| 4ag7 | COA | Glucosamine 6-phosphate N-acetyltransferase | / | 0.458 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.458 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.458 | |
| 4xz3 | COA | Acyl-CoA synthetase (NDP forming) | / | 0.458 | |
| 5fsx | ADP | Uncharacterized protein | / | 0.458 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.457 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1gwr | EST | Estrogen receptor | / | 0.457 | |
| 1ju6 | LYA | Thymidylate synthase | 2.1.1.45 | 0.457 | |
| 1kt6 | RTL | Retinol-binding protein 4 | / | 0.457 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.457 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.457 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.457 | |
| 2ea1 | GPG | Ribonuclease I | 3.1.27.6 | 0.457 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.457 | |
| 2owb | 626 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.457 | |
| 3ar7 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.457 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.457 | |
| 3fl8 | RAR | Dihydrofolate reductase | / | 0.457 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.457 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.457 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.457 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.457 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.457 | |
| 3zux | TCH | Transporter | / | 0.457 | |
| 4equ | G6I | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.457 | |
| 4okx | 198 | Androgen receptor | / | 0.457 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.457 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.456 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 1kce | CB3 | Thymidylate synthase | / | 0.456 | |
| 1m7a | MQU | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1ne6 | SP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.456 | |
| 1wpg | ADP | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.456 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 2bla | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.456 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.456 | |
| 2ejz | SAH | Diphthine synthase | / | 0.456 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.456 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.456 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.456 | |
| 2w9g | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.456 | |
| 3duf | R1T | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.456 | |
| 3duf | R1T | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.456 | |
| 3eek | 53S | Uncharacterized protein | / | 0.456 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.456 | |
| 3tqx | PLP | 2-amino-3-ketobutyrate coenzyme A ligase | / | 0.456 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.456 | |
| 4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.456 | |
| 4hxy | NDP | Plm1 | / | 0.456 | |
| 4v01 | 0LI | Fibroblast growth factor receptor 1 (Fms-related tyrosine kinase 2, Pfeiffer syndrome), isoform CRA_b | / | 0.456 | |
| 5c2t | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.456 | |
| 5fkn | TDC | Tetracycline repressor protein class D | / | 0.456 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.455 | |
| 1juj | LYA | Thymidylate synthase | 2.1.1.45 | 0.455 | |
| 1juv | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.455 | |
| 1svm | ATP | Large T antigen | 3.6.4 | 0.455 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.455 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.455 | |
| 2in6 | 839 | Wee1-like protein kinase | 2.7.10.2 | 0.455 | |
| 2pam | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.455 | |
| 2pnu | ENM | Androgen receptor | / | 0.455 | |
| 2ykc | YKC | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.455 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 4awo | 99B | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 4boe | CLR | Japanin | / | 0.455 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.455 | |
| 4eft | EFT | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 4if5 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.455 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.455 | |
| 4rqu | NAD | Alcohol dehydrogenase class-P | / | 0.455 | |
| 1al8 | DHP | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.454 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 1uhl | MEI | Retinoic acid receptor RXR-beta | / | 0.454 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.454 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.454 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 2pau | D5M | 5'-deoxynucleotidase YfbR | / | 0.454 | |
| 2xke | WI2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.454 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.454 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.454 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.454 | |
| 3ix8 | TX3 | Transcriptional activator protein LasR | / | 0.454 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.454 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.454 | |
| 3kr6 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.454 | |
| 3qlx | QLR | Uncharacterized protein | / | 0.454 | |
| 4b5p | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.454 | |
| 4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 0.454 | |
| 4egn | TWO | Cytochrome P450 | / | 0.454 | |
| 4ehy | ADP | Tetraacyldisaccharide 4'-kinase | / | 0.454 | |
| 4eqw | FAD | Coenzyme A disulfide reductase | / | 0.454 | |
| 4gev | CB3 | Thymidylate synthase | / | 0.454 | |
| 4hw2 | 19H | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.454 | |
| 4i13 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 4imo | PWZ | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.454 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.454 | |
| 4jq2 | SUZ | Aldo-keto reductase family 1 member C2 | / | 0.454 | |
| 4jva | 1OR | cAMP-dependent protein kinase type II-beta regulatory subunit | / | 0.454 | |
| 4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 4zzj | CNA | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.454 | |
| 5a9s | NAP | Putative dehydrogenase | / | 0.454 | |
| 5bn3 | ADP | V-type ATP synthase alpha chain | / | 0.454 | |
| 5bn3 | ADP | NEQ263 | / | 0.454 | |
| 5dp2 | NAP | CurF | / | 0.454 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.454 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.453 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.453 | |
| 1e1q | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.453 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 1fm9 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.453 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1zw9 | H64 | ATP-dependent molecular chaperone HSP82 | / | 0.453 | |
| 2acw | UPG | Glycosyltransferase | / | 0.453 | |
| 2g97 | DGB | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.453 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.453 | |
| 2ji9 | TPW | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.453 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.453 | |
| 3iqf | E4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.453 | |
| 3jwm | 5WB | Dihydrofolate reductase | / | 0.453 | |
| 3t37 | FAD | Pyridoxine 4-oxidase | / | 0.453 | |
| 3tm4 | SAM | Uncharacterized protein | / | 0.453 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.453 | |
| 4emy | PLP | Aminotransferase class I and II | / | 0.453 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.453 | |
| 4m11 | MXM | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.453 | |
| 4n57 | ADP | APH(2'')-Id | / | 0.453 | |
| 4rri | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.453 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.453 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.452 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.452 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.452 | |
| 1mdr | APG | Mandelate racemase | / | 0.452 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.452 | |
| 1syn | F89 | Thymidylate synthase | / | 0.452 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.452 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 2pmd | GNP | Translation initiation factor 2 subunit gamma | / | 0.452 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.452 | |
| 3w8w | FAD | Putative FAD-dependent oxygenase EncM | / | 0.452 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.452 | |
| 4elf | 35I | Dihydrofolate reductase | / | 0.452 | |
| 4g34 | 924 | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.452 | |
| 4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.452 | |
| 4k6i | 9RA | Retinoic acid receptor RXR-alpha | / | 0.452 | |
| 4lvb | 20N | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.452 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 4zm3 | PLP | Aminotransferase | / | 0.452 | |
| 5aqz | SGV | Heat shock 70 kDa protein 1A | / | 0.452 | |
| 1ahi | CHO | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.451 | |
| 1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 1lco | PPY | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.451 | |
| 1nlm | UD1 | UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase | / | 0.451 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 1z4i | UMP | 5'(3')-deoxyribonucleotidase, mitochondrial | 3.1.3 | 0.451 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 2bgl | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.451 | |
| 2chw | 039 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2iht | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.451 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.451 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.451 | |
| 3ac2 | KSE | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.451 | |
| 3csd | EMO | Putative ketoacyl reductase | 1.3.1 | 0.451 | |
| 3dg8 | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 3frf | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.451 | |
| 3hub | 469 | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.451 | |
| 3wsj | MK1 | Protease | / | 0.451 | |
| 4b1f | KRH | Glutamate racemase | / | 0.451 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 4c49 | HCY | Corticosteroid-binding globulin | / | 0.451 | |
| 4elb | 34R | Dihydrofolate reductase | / | 0.451 | |
| 4elg | 52J | Dihydrofolate reductase | / | 0.451 | |
| 4feu | 537 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.451 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.451 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4iae | 1DX | Alr2278 protein | / | 0.451 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.451 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4l2z | S7M | S-adenosylmethionine synthase | / | 0.451 | |
| 4lww | LWW | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.451 | |
| 4psw | COA | Histone acetyltransferase type B catalytic subunit | / | 0.451 | |
| 4yp6 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.451 | |
| 1cqs | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.450 | |
| 1dlj | UGA | UDP-glucose 6-dehydrogenase | / | 0.450 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1piw | NAP | NADP-dependent alcohol dehydrogenase 6 | 1.1.1.2 | 0.450 | |
| 1s3w | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.450 | |
| 1std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.450 | |
| 1tsd | F89 | Thymidylate synthase | / | 0.450 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 1zdw | FLV | Prenyltransferase | / | 0.450 | |
| 2b04 | CHO | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.450 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.450 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.450 | |
| 2rds | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.450 | |
| 2z1w | BDI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.450 | |
| 3aba | FLI | Cytochrome P450 | / | 0.450 | |
| 3clb | TMQ | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 3ogw | IMN | Lactoperoxidase | 1.11.1.7 | 0.450 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 3qdd | 94M | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.450 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.450 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.450 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 3x0a | 5GP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.450 | |
| 3zuy | TCH | Transporter | / | 0.450 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.450 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.450 | |
| 4hyf | 1AK | Tankyrase-2 | 2.4.2.30 | 0.450 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.450 | |
| 4okw | 198 | Androgen receptor | / | 0.450 | |
| 4xzj | NAD | Putative NAD(+)--arginine ADP-ribosyltransferase Vis | 2.4.2.31 | 0.450 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.450 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.449 | |
| 1k8y | 13P | Tryptophan synthase alpha chain | / | 0.449 | |
| 1mab | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.449 | |
| 1qzf | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.449 | |
| 1s4d | SAH | Uroporphyrinogen-III C-methyltransferase | 2.1.1.107 | 0.449 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1zxn | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.449 | |
| 2a19 | ANP | Interferon-induced, double-stranded RNA-activated protein kinase | 2.7.11.1 | 0.449 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.449 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2j9g | ADP | Biotin carboxylase | 6.3.4.14 | 0.449 | |
| 2psj | CEI | Renilla-luciferin 2-monooxygenase | 1.13.12.5 | 0.449 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.449 | |
| 2w3w | VG9 | Dihydrofolate reductase | / | 0.449 | |
| 3dh7 | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.449 | |
| 3djf | BC3 | Purine nucleoside phosphorylase | / | 0.449 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.449 | |
| 3i6r | J5Z | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.449 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3q5k | D1U | Heat shock protein 83-1 | / | 0.449 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.449 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.449 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.449 | |
| 4iqq | UMP | Thymidylate synthase | / | 0.449 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.449 | |
| 4l17 | DNQ | Glutamate receptor 2 | / | 0.449 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.449 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.449 | |
| 1axw | MTX | Thymidylate synthase | / | 0.448 | |
| 1dg5 | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1fvp | FMA | Non-fluorescent flavoprotein | / | 0.448 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.448 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.448 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.448 | |
| 1omo | NAD | Alanine dehydrogenase | / | 0.448 | |
| 1v08 | NTZ | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.448 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.448 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.448 | |
| 2gd2 | CAA | Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase ) | / | 0.448 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.448 | |
| 2qqf | A1R | NAD-dependent protein deacetylase HST2 | 3.5.1 | 0.448 | |
| 2rl1 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.448 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.448 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.448 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.448 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.448 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.448 | |
| 3sl6 | JN8 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 3toz | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.448 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.448 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.448 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.448 | |
| 4g8b | HL6 | Alpha/beta hydrolase fold protein | / | 0.448 | |
| 4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.448 | |
| 4jhz | 1KV | Beta-glucuronidase | 3.2.1.31 | 0.448 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.448 | |
| 4ug5 | H4B | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.448 | |
| 5iot | UMP | Flavin-dependent thymidylate synthase | 2.1.1.148 | 0.448 | |
| 5kf2 | COA | Predicted acetyltransferase | / | 0.448 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1ftl | DNQ | Glutamate receptor 2 | / | 0.447 | |
| 1i5a | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.447 | |
| 1o6r | R19 | Squalene--hopene cyclase | 4.2.1.129 | 0.447 | |
| 1q3g | UDA | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.447 | |
| 1tka | N3T | Transketolase 1 | 2.2.1.1 | 0.447 | |
| 1upb | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.447 | |
| 1xiu | REA | Retinoic acid receptor RXR | / | 0.447 | |
| 2bak | AQZ | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.447 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.447 | |
| 2op0 | 7PC | Enoyl-ACP reductase | / | 0.447 | |
| 2xf3 | J01 | Uncharacterized protein | / | 0.447 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.447 | |
| 3fr4 | F8A | Fatty acid-binding protein, adipocyte | / | 0.447 | |
| 3ld6 | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.447 | |
| 3lt2 | FT3 | Enoyl-ACP reductase | / | 0.447 | |
| 3ngl | NAP | Bifunctional protein FolD | / | 0.447 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3p8z | 36A | Genome polyprotein | 2.1.1.56 | 0.447 | |
| 3rpn | GTX | Glutathione S-transferase kappa 1 | 2.5.1.18 | 0.447 | |
| 4a9y | AQZ | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 4ddr | MMV | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 4ij1 | 17C | Anthranilate phosphoribosyltransferase | / | 0.447 | |
| 4iqq | D16 | Thymidylate synthase | / | 0.447 | |
| 4k9y | K9Y | Focal adhesion kinase 1 | 2.7.10.2 | 0.447 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 4ork | GDP | Bifunctional AAC/APH | 2.3.1 | 0.447 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.447 | |
| 4x5f | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 4zhi | ADP | Kinesin-like protein KIF11 | / | 0.447 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.447 | |
| 5jjs | SAH | Genome polyprotein | / | 0.447 | |
| 1b87 | ACO | Aac(6')-Ii protein | / | 0.446 | |
| 1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1guy | NAD | Malate dehydrogenase | / | 0.446 | |
| 1h74 | AGS | Homoserine kinase | 2.7.1.39 | 0.446 | |
| 1hk5 | T44 | Serum albumin | / | 0.446 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.446 | |
| 1kqn | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.446 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.446 | |
| 1m76 | CAA | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.446 | |
| 1w19 | T1P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
| 1zos | MTM | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | / | 0.446 | |
| 2avv | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.446 | |
| 2e98 | B29 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.446 | |
| 2gfs | PQB | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 2gq3 | COA | Malate synthase G | / | 0.446 | |
| 2od7 | A1R | NAD-dependent protein deacetylase HST2 | 3.5.1 | 0.446 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 2oz5 | 7XY | Uncharacterized protein | / | 0.446 | |
| 2pda | TPP | Pyruvate synthase | / | 0.446 | |
| 2qo4 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.446 | |
| 3eej | 53R | Uncharacterized protein | / | 0.446 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.446 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.446 | |
| 3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.446 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.446 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 3sa2 | 7DR | Dihydrofolate reductase | / | 0.446 | |
| 3v4t | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.446 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.446 | |
| 3x02 | 5GP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.446 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.446 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.446 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 4cav | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.446 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.446 | |
| 4gue | QCT | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.446 | |
| 4ku5 | DCC | 3-oxoacyl-[ACP] synthase III | / | 0.446 | |
| 4l8u | 9AZ | Serum albumin | / | 0.446 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 4mv3 | ACP | Biotin carboxylase | 6.3.4.14 | 0.446 | |
| 4okt | 198 | Androgen receptor | / | 0.446 | |
| 4qmy | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.446 | |
| 4x5j | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.446 | |
| 5ahk | TPP | Acetolactate synthase II, large subunit | / | 0.446 | |
| 3pwh | ZMA | Adenosine receptor A2a | / | 0.446 | |
| 1men | GAR | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.445 | |
| 1mjt | NAD | Nitric oxide synthase oxygenase | / | 0.445 | |
| 1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.445 | |
| 1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.445 | |
| 1q51 | CAA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.445 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.445 | |
| 1xds | DRA | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.445 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.445 | |
| 2azy | CHD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.445 | |
| 2bns | MST | Reaction center protein L chain | / | 0.445 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.445 | |
| 2ihv | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.445 | |
| 2pup | ADP | Methylthioribose kinase | 2.7.1.100 | 0.445 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.445 | |
| 2xvv | 9DN | Serum albumin | / | 0.445 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.445 | |
| 2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.445 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 3dej | RXC | Caspase-3 | 3.4.22.56 | 0.445 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 3fko | FKO | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.445 | |
| 3tgp | GNP | GTPase HRas | / | 0.445 | |
| 3u9e | COA | Lmo1369 protein | / | 0.445 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.445 | |
| 3zkp | ERB | Erythromycin C-12 hydroxylase | 1.14.13.154 | 0.445 | |
| 4fgh | 0U6 | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.445 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.445 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.445 | |
| 4gs4 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.445 | |
| 4k36 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.445 | |
| 4k9n | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.445 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 4mpr | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.445 | |
| 4oe4 | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.445 | |
| 5cp8 | TCU | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 5eso | TDP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.445 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1h8h | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.444 | |
| 1h8h | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.444 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.444 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.444 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.444 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 1ryw | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.444 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.444 | |
| 1t13 | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | / | 0.444 | |
| 1uym | PU3 | Heat shock protein HSP 90-beta | / | 0.444 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1w29 | TS1 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.444 | |
| 1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.444 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.444 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.444 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.444 | |
| 2bel | CBO | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 2bfo | NDP | Pteridine reductase 1 | 1.5.1.33 | 0.444 | |
| 2fa3 | ACO | Hydroxymethylglutaryl-CoA synthase | / | 0.444 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.444 | |
| 2w3a | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 2wqp | WQP | Polysialic acid capsule biosynthesis protein SiaC | / | 0.444 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.444 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 3ghh | 2NF | CD38 molecule | / | 0.444 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.444 | |
| 3ict | ADP | Coenzyme A disulfide reductase | / | 0.444 | |
| 3iqe | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.444 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.444 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.444 | |
| 3zhv | TDW | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.444 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.444 | |
| 4hai | I23 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.444 | |
| 4k7y | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.444 | |
| 4ktf | 1TM | Cytochrome P450 | / | 0.444 | |
| 4lch | 1WN | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.444 | |
| 4m8h | R4M | Retinoic acid receptor RXR-alpha | / | 0.444 | |
| 4pv5 | CBW | Lactoylglutathione lyase | 4.4.1.5 | 0.444 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.444 | |
| 4zqc | F6F | Tryptophan synthase alpha chain | / | 0.444 | |
| 5cho | FAD | Flavin reductase | / | 0.444 | |
| 5doz | NDP | JamJ | / | 0.444 | |
| 5g3s | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.444 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.444 | |
| 1dyh | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.443 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.443 | |
| 1mxf | MTX | Putative pteridine reductase 2 | / | 0.443 | |
| 1s36 | CEI | Obelin | / | 0.443 | |
| 1u2d | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.443 | |
| 1vgq | CAO | Formyl-CoA:oxalate CoA-transferase | / | 0.443 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.443 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.443 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.443 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.443 | |
| 2r2n | KYN | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.443 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.443 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.443 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.443 | |
| 3fnh | JPJ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.443 | |
| 3glu | LYS_VAL_MET | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.443 | |
| 3n39 | FMN | Protein NrdI | / | 0.443 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.443 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.443 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.443 | |
| 3zht | TD9 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.443 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.443 | |
| 4azm | T4B | Fatty acid-binding protein, epidermal | / | 0.443 | |
| 4eix | NIM | Phospholipase A2 VRV-PL-VIIIa | / | 0.443 | |
| 4epw | GDP | GTPase KRas | / | 0.443 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.443 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4iw8 | KN3 | Estrogen receptor | / | 0.443 | |
| 4j52 | 1J3 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.443 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.443 | |
| 4ea3 | 0NN | Nociceptin receptor | / | 0.443 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.442 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1lhu | EST | Sex hormone-binding globulin | / | 0.442 | |
| 1qax | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.442 | |
| 1sn0 | T44 | Transthyretin | / | 0.442 | |
| 1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.442 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.442 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.442 | |
| 2e99 | B08 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.442 | |
| 2j09 | FMN | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.442 | |
| 2mjp | ANP | dITP/XTP pyrophosphatase | 3.6.1.19 | 0.442 | |
| 2oo5 | TXD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.442 | |
| 2qx7 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.442 | |
| 2r6j | NDP | Eugenol synthase 1 | 1.1.1.318 | 0.442 | |
| 2vkv | TDC | Tetracycline repressor protein class D | / | 0.442 | |
| 2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.442 | |
| 2yej | ZZ3 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 2z1x | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.442 | |
| 2zym | ACX | Periplasmic binding protein | / | 0.442 | |
| 3d4b | DZD | NAD-dependent protein deacetylase | / | 0.442 | |
| 3dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3fy9 | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 3gwl | FAD | FAD-linked sulfhydryl oxidase | 1.8.3.2 | 0.442 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.442 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.442 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.442 | |
| 3saz | 043 | Malate synthase G | / | 0.442 | |
| 3t5i | SER_SER_CMT_FAR | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.442 | |
| 3um8 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.442 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 4bqh | 9VU | UDP-N-acetylglucosamine pyrophosphorylase, putative | / | 0.442 | |
| 4br0 | AU1 | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.442 | |
| 4el9 | AFE | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.442 | |
| 4fwf | FAD | Lysine-specific histone demethylase 1B | 1 | 0.442 | |
| 4idg | NAD | Putative UDP-glucose 4-epimerase | / | 0.442 | |
| 4kfq | KFQ | Glutamate receptor ionotropic, NMDA 1 | / | 0.442 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.442 | |
| 4kox | CLS | Uncharacterized protein | / | 0.442 | |
| 4o4e | ATP | Kinase | / | 0.442 | |
| 4o7u | THF | Thymidylate synthase | / | 0.442 | |
| 4oqy | NDP | (S)-imine reductase | / | 0.442 | |
| 4wx2 | F6F | Tryptophan synthase alpha chain | / | 0.442 | |
| 4wx2 | F6F | Tryptophan synthase beta chain | 4.2.1.20 | 0.442 | |
| 4zp0 | DXC | Multidrug transporter MdfA | / | 0.442 | |
| 5c4i | TPP | Oxalate oxidoreductase subunit alpha | / | 0.442 | |
| 5c4i | TPP | Oxalate oxidoreductase subunit beta | / | 0.442 | |
| 5c80 | URI | Uridine phosphorylase | / | 0.442 | |
| 7dfr | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1fm6 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.441 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 1rdt | L79 | Retinoic acid receptor RXR-alpha | / | 0.441 | |
| 1x8b | 824 | Wee1-like protein kinase | 2.7.10.2 | 0.441 | |
| 2b35 | TCL | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.441 | |
| 2fjm | 073 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.441 | |
| 2i0y | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.441 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 2qo6 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.441 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.441 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.441 | |
| 2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3be2 | RAJ | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.441 | |
| 3eon | 341 | Glutaryl-CoA dehydrogenase | / | 0.441 | |
| 3g8e | IS1 | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.441 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.441 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.441 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 3pdt | ADP | Myosin heavy chain kinase A | 2.7.11.7 | 0.441 | |
| 3qiz | QI2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.441 | |
| 3tdl | 11D | Serum albumin | / | 0.441 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 4bfs | ZVS | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.441 | |
| 4ixg | IXG | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4j49 | 1J1 | Uncharacterized protein | / | 0.441 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.441 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.441 | |
| 5cvc | PLP | Serine racemase | / | 0.441 | |
| 1ci7 | UMP | Thymidylate synthase | 2.1.1.45 | 0.440 | |
| 1dd6 | MCI | Metallo-beta-lactamase type 2 | / | 0.440 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.440 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 1gt5 | BZQ | Odorant-binding protein | / | 0.440 | |
| 1i5c | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.440 | |
| 1lbb | KAI | Glutamate receptor 2 | / | 0.440 | |
| 1mra | APG | Mandelate racemase | / | 0.440 | |
| 1ozq | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.440 | |
| 1ra3 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2amb | 17H | Androgen receptor | / | 0.440 | |
| 2bif | ANP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | 2.7.1.105 | 0.440 | |
| 2c9d | PHR | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.440 | |
| 2hma | SAM | tRNA-specific 2-thiouridylase MnmA | / | 0.440 | |
| 2ilt | NN1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.440 | |
| 2vb8 | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.440 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.440 | |
| 2y4m | GDX | Uncharacterized protein | / | 0.440 | |
| 2yej | XQK | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.440 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.440 | |
| 2zza | FOL | Dihydrofolate reductase | / | 0.440 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.440 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.440 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.440 | |
| 3cvu | FAD | RE11660p | / | 0.440 | |
| 3d74 | NBB | Pheromone-binding protein ASP1 | / | 0.440 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.440 | |
| 3dei | RXB | Caspase-3 | 3.4.22.56 | 0.440 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.440 | |
| 3hav | ATP | Aminoglycoside phosphotransferase | / | 0.440 | |
| 3huc | G97 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 3l03 | 4OH | Estrogen receptor | / | 0.440 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.440 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.440 | |
| 3qf9 | NM8 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 3qsa | TA7 | Anthranilate phosphoribosyltransferase | / | 0.440 | |
| 3stv | 3HO | Methylketone synthase I | / | 0.440 | |
| 3tfq | 07M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3vev | 0H4 | Glucokinase | 2.7.1.2 | 0.440 | |
| 3vjc | ZGA | Squalene synthase | 2.5.1.21 | 0.440 | |
| 4aox | FAD | Steroid monooxygenase | / | 0.440 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.440 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4iwv | 1J9 | Glucokinase | 2.7.1.2 | 0.440 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.440 | |
| 4jt8 | 1NR | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.440 | |
| 4kf1 | HT5 | Aryldialkylphosphatase | 3.1.8.1 | 0.440 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.440 | |
| 4lpk | GDP | GTPase KRas | / | 0.440 | |
| 4lt6 | 3AT | Poly(A) polymerase gamma | 2.7.7.19 | 0.440 | |
| 4r7u | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.440 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.440 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.440 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.440 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.440 | |
| 8cat | NDP | Catalase | 1.11.1.6 | 0.440 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.440 |