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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3qgzADNHistidine triad nucleotide-binding protein 13

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
3qgzADNHistidine triad nucleotide-binding protein 131.000
1rzy5ASHistidine triad nucleotide-binding protein 130.746
4eqeKAAHistidine triad nucleotide-binding protein 130.635
4eqgA5AHistidine triad nucleotide-binding protein 130.622
5i2fBS5Histidine triad nucleotide-binding protein 130.606
3oxk5GPHistidine triad nucleotide-binding protein30.601
1av5AP2Histidine triad nucleotide-binding protein 130.592
3n1t5GPPurine nucleoside phosphoramidase/0.565
4egu5GPPutative histidine triad (HIT) protein/0.531
3gkjHC3Niemann-Pick C1 protein/0.511
1uydPU8Heat shock protein HSP 90-alpha/0.504
4rrdA3TProbable threonine--tRNA ligase 26.1.1.30.501
2x6o2TCTetracycline repressor protein class D/0.499
1mvsDTMDihydrofolate reductase1.5.1.30.497
3anmNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.495
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.495
4demYS4Farnesyl pyrophosphate synthase2.5.1.100.494
3djlFADPutative acyl-CoA dehydrogenase AidB1.3.990.493
3h3qH13Collagen type IV alpha-3-binding protein/0.493
4l2xYL2Farnesyl pyrophosphate synthase2.5.1.100.493
2z3uCRRCytochrome P450/0.492
3ndjJHZMethyltransferase/0.491
2rehFADNitroalkane oxidase1.7.3.10.490
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.490
1ie9VDXVitamin D3 receptor/0.489
2pg0FADAcyl-CoA dehydrogenase/0.489
3nmhPYVAbscisic acid receptor PYL2/0.489
4xe606UDihydrofolate reductase1.5.1.30.489
2ykcYKCHeat shock protein HSP 90-alpha/0.488
4fweFADLysine-specific histone demethylase 1B10.488
5g53NECAdenosine receptor A2a/0.488
1s0zEB1Vitamin D3 receptor/0.487
2ykjYKJHeat shock protein HSP 90-alpha/0.486
5il2SAHN6-adenosine-methyltransferase 70 kDa subunit/0.486
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.485
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.485
2wn6NDPADP-ribosyltransferase enzymatic component/0.484
3tp0FO5HTH-type transcriptional regulator EthR/0.484
1qs2NADVip2Ac/0.483
3a783EVVitamin D3 receptor/0.483
3m7rVDXVitamin D3 receptor/0.483
3sfeFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.483
1o6qR17Squalene--hopene cyclase4.2.1.1290.482
1uy7PU4Heat shock protein HSP 90-alpha/0.482
3cgtBCDCyclomaltodextrin glucanotransferase2.4.1.190.482
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.482
4ky404JBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.482
1db1VDXVitamin D3 receptor/0.481
2wo7ASVIsopenicillin N synthase1.21.3.10.481
2ydoADNAdenosine receptor A2a/0.481
2zlcVDXVitamin D3 receptor/0.481
1buxPPSNucleoside diphosphate kinase, cytosolic2.7.4.60.480
1dnaCB3Thymidylate synthase/0.480
1trgCB3Thymidylate synthase/0.480
2i65NADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.480
3up0D7SaceDAF-12/0.480
3wthIM4Acetylcholine-binding protein/0.480
3zc5W9ZHepatocyte growth factor receptor2.7.10.10.480
4klaCHDFerrochelatase, mitochondrial4.99.1.10.480
4nh82LCHeat shock protein HSP 90-alpha/0.480
1uyePU9Heat shock protein HSP 90-alpha/0.479
2wi72KLHeat shock protein HSP 90-alpha/0.479
3ar4TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.479
3dlcSAMSAM (And some other nucleotide) binding motif:Generic methyltransferase/0.479
3h4vNAPPteridine reductase 11.5.1.330.479
3o8gO8GHTH-type transcriptional regulator EthR/0.479
4kp71UQ1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.479
1ie8KH1Vitamin D3 receptor/0.478
2ghtSER_PRO_THR_PRO_SEPCarboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 13.1.3.160.478
3ar6TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.478
3o0iP54Heat shock protein HSP 90-alpha/0.478
4fdnFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.478
4rr6A3SProbable threonine--tRNA ligase 26.1.1.30.478
1nqmBTNStreptavidin/0.477
1uyhPU0Heat shock protein HSP 90-alpha/0.477
1zgaHMKIsoflavone 4'-O-methyltransferase/0.477
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.477
3vtdTKDVitamin D3 receptor/0.477
1hrvSDZGenome polyprotein/0.476
1it7GUNtRNA-guanine(15) transglycosylase2.4.2.480.476
1uyfPU1Heat shock protein HSP 90-alpha/0.476
2bn4FADNADPH--cytochrome P450 reductase/0.476
2harOCCVitamin D3 receptor/0.476
2ojg19AMitogen-activated protein kinase 12.7.11.240.476
2qo4CHDFatty acid-binding protein 10-A, liver basic/0.476
2vbpVB1Isopenicillin N synthase1.21.3.10.476
2xtbKRMAdenosine kinase, putative/0.476
3b5iSAHIndole-3-acetate O-methyltransferase 1/0.476
4e32DWNMethyltransferase/0.476
4frs0V6Beta-secretase 13.4.23.460.476
4gh10WXQueuine tRNA-ribosyltransferase2.4.2.290.476
4gkt0O1Queuine tRNA-ribosyltransferase2.4.2.290.476
4i1nFOLDihydrofolate reductase1.5.1.30.476
3lm4HPXCatechol 2,3-dioxygenase/0.475
3ms5REEGamma-butyrobetaine dioxygenase1.14.11.10.475
3q0uLL3HTH-type transcriptional regulator EthR/0.475
4ap0ADPKinesin-like protein KIF11/0.475
4bb6HD1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.475
4c35NU3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.475
4g2i0VQVitamin D3 receptor/0.475
4imfSI3N-acetylneuraminate lyase/0.475
4q0a4OAVitamin D3 receptor A/0.475
1h35R01Squalene--hopene cyclase4.2.1.1290.474
1hvyD16Thymidylate synthase2.1.1.450.474
1jomFFODihydrofolate reductase1.5.1.30.474
1tl3H20Gag-Pol polyprotein2.7.7.490.474
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.474
2zxbZXBAlpha-L-fucosidase, putative/0.474
4rr7A3SProbable threonine--tRNA ligase 26.1.1.30.474
4rrmA3TProbable threonine--tRNA ligase 26.1.1.30.474
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.474
4uhrNGIAdenosine receptor A2a/0.474
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.473
2uywBTNAvd protein/0.473
2zl9VDAVitamin D3 receptor/0.473
3bw4FMNPutative 2-nitropropane dioxygenase/0.473
3juoAJDPhenazine biosynthesis protein A/B/0.473
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.473
4ifvT27Gag-Pol polyprotein2.7.7.490.473
1rkhVD2Vitamin D3 receptor/0.472
1uy8PU5Heat shock protein HSP 90-alpha/0.472
2hamC33Vitamin D3 receptor/0.472
3oogYTPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.472
4b78KGGBeta-secretase 13.4.23.460.472
4fps0UXQueuine tRNA-ribosyltransferase2.4.2.290.472
5fitAP2Bis(5'-adenosyl)-triphosphatase3.6.1.290.472
1l8aTDPPyruvate dehydrogenase E1 component1.2.4.10.471
1s19MC9Vitamin D3 receptor/0.471
2bbqPFGThymidylate synthase/0.471
2hb8MVDVitamin D3 receptor/0.471
3hf6LX0Tryptophan 5-hydroxylase 11.14.16.40.471
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.471
4az0S61Lysosomal protective protein3.4.16.50.471
4dscA8SAbscisic acid receptor PYL3/0.471
4fqsLYAThymidylate synthase ThyA/0.471
4h5cYS4Farnesyl pyrophosphate synthase2.5.1.100.471
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.471
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.471
1rt7UC4Gag-Pol polyprotein2.7.7.490.470
2hb7O1CVitamin D3 receptor/0.470
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.470
3kpzZNEVitamin D3 receptor/0.470
3q0vLL4HTH-type transcriptional regulator EthR/0.470
3q8uADPNucleoside diphosphate kinase/0.470
3vt5YI2Vitamin D3 receptor/0.470
1q19SSCCarbapenam-3-carboxylate synthase6.3.3.60.469
1tlcF89Thymidylate synthase/0.469
1uuoBRFDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.469
2hr8SAHDiphthine synthase/0.469
2p83MR0Beta-secretase 13.4.23.460.469
2pa7TYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.469
2ph835ABeta-secretase 13.4.23.460.469
2q28ADPOxalyl-CoA decarboxylase4.1.1.80.469
3fktSIIBeta-secretase 13.4.23.460.469
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.469
3vt3VDXVitamin D3 receptor/0.469
4gevCB3Thymidylate synthase/0.469
4ia3BIVVitamin D3 receptor A/0.469
4jv81M1Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.469
1c1c612Gag-Pol polyprotein2.7.7.490.468
1rjkVDZVitamin D3 receptor/0.468
1uykPUXHeat shock protein HSP 90-alpha/0.468
1z6tADPApoptotic protease-activating factor 1/0.468
2hq9FADMll6688 protein/0.468
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.468
2z7gEH9Adenosine deaminase3.5.4.40.468
3gluLYS_VAL_METNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.468
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.468
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.468
3zy3GDPGDP-fucose protein O-fucosyltransferase 12.4.1.2210.468
4gi40EXQueuine tRNA-ribosyltransferase2.4.2.290.468
4x7uZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.468
1uy9PU6Heat shock protein HSP 90-alpha/0.467
3cz7ACOHistone acetyltransferase RTT1092.3.1.480.467
3dzl3OCPhenazine biosynthesis protein A/B/0.467
3oq13OQCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.467
3vg9ZMAAdenosine receptor A2a/0.467
3w0hW12Vitamin D3 receptor/0.467
3w5rLOAVitamin D3 receptor/0.467
4g1y0VOVitamin D3 receptor A/0.467
4h3j10WBeta-secretase 13.4.23.460.467
5ej9TPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.467
5f2kSAHUncharacterized protein/0.467
5hwpCOAHydroxymethylglutaryl-CoA synthase/0.467
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.467
1ja0NAPNADPH--cytochrome P450 reductase/0.466
1mabADPATP synthase subunit beta, mitochondrial3.6.3.140.466
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.466
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.466
3dr1C5DVitamin D3 receptor A/0.466
4a6rTA8Probable aminotransferase/0.466
4deg0JJHepatocyte growth factor receptor2.7.10.10.466
4dw60MNHTH-type transcriptional regulator EthR/0.466
4i6gFADCryptochrome-2/0.466
4relKMPGlycosyltransferase/0.466
1dnpFADDeoxyribodipyrimidine photo-lyase4.1.99.30.465
1rk3VDXVitamin D3 receptor/0.465
1uyiPUZHeat shock protein HSP 90-alpha/0.465
1zw9H64ATP-dependent molecular chaperone HSP82/0.465
2fjaFADAdenylylsulfate reductase, subunit A (AprA)/0.465
2h55DZ8Heat shock protein HSP 90-alpha/0.465
2yjxYJXHeat shock protein HSP 90-alpha/0.465
3h2sNDPPutative NADH-flavin reductase/0.465
3occDIHPurine nucleoside phosphorylase DeoD-type/0.465
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.465
3zxzKRWHepatocyte growth factor receptor2.7.10.10.465
4cd2FOLDihydrofolate reductase1.5.1.30.465
4iteTEYVitamin D3 receptor/0.465
4l17DNQGlutamate receptor 2/0.465
4q15HFGProline--tRNA ligase6.1.1.150.465
4uqsINENitric oxide synthase oxygenase1.14.13.1650.465
2hc4VDXVitamin D3 receptor A/0.464
2ykeYKEHeat shock protein HSP 90-alpha/0.464
3gb4D3MDdmC/0.464
4hfr14MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.464
4phlPILPhosphodiesterase/0.464
1j3kWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.463
1q9mROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.463
2ftoCB3Thymidylate synthase/0.463
2zu9GDPMannosyl-3-phosphoglycerate synthase2.4.1.2170.463
3a8wATPProtein kinase C iota type2.7.11.130.463
3l0lHC3Nuclear receptor ROR-gamma/0.463
3nj0PYVAbscisic acid receptor PYL2/0.463
4a9mP9MBromodomain-containing protein 2/0.463
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.463
4wevSUZAldo-keto reductase family 1 member B101.1.10.463
5bp9SAHPutative methyltransferase protein/0.463
5cwa0GAAnthranilate synthase component 14.1.3.270.463
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.462
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.462
1fvpFMANon-fluorescent flavoprotein/0.462
1pvdTPPPyruvate decarboxylase isozyme 1/0.462
1q4wDQUQueuine tRNA-ribosyltransferase2.4.2.290.462
1txiTX5Vitamin D3 receptor/0.462
1uy6PU3Heat shock protein HSP 90-alpha/0.462
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.462
2bx8AZQSerum albumin/0.462
2fwzH71Heat shock protein HSP 90-alpha/0.462
2hveADPNucleoside diphosphate kinase A2.7.4.60.462
2xdrNDPNAD/NADP-dependent betaine aldehyde dehydrogenase/0.462
2ykiYKIHeat shock protein HSP 90-alpha/0.462
3g1lRF2HTH-type transcriptional regulator EthR/0.462
3hz5Z64Heat shock protein HSP 90-alpha/0.462
3kt8LTNTryptophan--tRNA ligase, cytoplasmic6.1.1.20.462
3nmpPYVAbscisic acid receptor PYL2/0.462
3w0yDS4Vitamin D3 receptor/0.462
3x2fNAIAdenosylhomocysteinase/0.462
3zh8C58Protein kinase C iota type2.7.11.130.462
4cavMYAGlycylpeptide N-tetradecanoyltransferase2.3.1.970.462
4g20484Vitamin D3 receptor A/0.462
4gutFADLysine-specific histone demethylase 1B10.462
5a2yUTPMitochondrial poly(A) polymerase/0.462
1nc1MTH5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase3.2.2.90.461
1uycPU7Heat shock protein HSP 90-alpha/0.461
1xduSFGAclacinomycin 10-hydroxylase RdmB4.1.10.461
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.461
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.461
2fk8SAMHydroxymycolate synthase MmaA42.1.10.461
2hasC3OVitamin D3 receptor/0.461
2iltNN1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.461
2isc223Purine nucleoside phosphorylase, putative/0.461
2pncCLUPrimary amine oxidase, liver isozyme/0.461
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.461
2yk2YJWHeat shock protein HSP 90-alpha/0.461
3aiqHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic3.2.1.1820.461
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.461
3lpkZ76Beta-secretase 13.4.23.460.461
3q43D66M1 family aminopeptidase3.4.110.461
3qp8HL0Transcriptional activator, LuxR/UhpA family of regulators/0.461
3vi5M4MHematopoietic prostaglandin D synthase/0.461
3vt7VDXVitamin D3 receptor/0.461
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4awq592Heat shock protein HSP 90-alpha/0.461
4bbyFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.461
4dan2FAPurine nucleoside phosphorylase DeoD-type2.4.2.10.461
4y1bNAPAntE/0.461
1pq944BOxysterols receptor LXR-beta/0.460
1ychFMNNitric oxide reductase10.460
2jblSMAReaction center protein L chain/0.460
2o7pNAPRiboflavin biosynthesis protein RibD/0.460
2wueKEK4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.460
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.460
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.460
3czr3CZCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.460
3fowIMHPurine nucleoside phosphorylase/0.460
3jwcEKBDihydrofolate reductase/0.460
4c6uTLG3-oxoacyl-ACP synthase/0.460
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.460
4qms1N1Serine/threonine-protein kinase 242.7.11.10.460
4u0sADPAdenosine monophosphate-protein transferase FICD2.7.7.n10.460
5kf9ACOPredicted acetyltransferase/0.460
1aiqCB3Thymidylate synthase/0.459
1bwlFMNNADPH dehydrogenase 11.6.99.10.459
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.459
1tezFADDeoxyribodipyrimidine photo-lyase4.1.99.30.459
1wklATPNucleoside diphosphate kinase/0.459
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.459
2eglSAHDiphthine synthase/0.459
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.459
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
2y05RALProstaglandin reductase 1/0.459
3c3eFO12-phospho-L-lactate transferase/0.459
3qm4PN0Cytochrome P450 2D6/0.459
3s7a684Dihydrofolate reductase1.5.1.30.459
3uaxNOSPurine nucleoside phosphorylase DeoD-type/0.459
3w5tLHPVitamin D3 receptor/0.459
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.459
4gki0JNAminoglycoside 3'-phosphotransferase AphA1-IAB/0.459
4h0xNADIota toxin component Ia/0.459
4rrxLURProstaglandin G/H synthase 21.14.99.10.459
1efzPRFQueuine tRNA-ribosyltransferase2.4.2.290.458
1nbiSAMGlycine N-methyltransferase2.1.1.200.458
1nq7ARLNuclear receptor ROR-beta/0.458
1o5rFR9Adenosine deaminase3.5.4.40.458
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.458
2cjpVPREpoxide hydrolase/0.458
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.458
2yeiXQIHeat shock protein HSP 90-alpha/0.458
3g1mRF3HTH-type transcriptional regulator EthR/0.458
3hf8ML0Tryptophan 5-hydroxylase 11.14.16.40.458
3jzfJZKBiotin carboxylase6.3.4.140.458
3of3DIHPurine nucleoside phosphorylase DeoD-type 1/0.458
3qppPFWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.458
4bb5HD2Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.458
4fex0TOAminoglycoside 3'-phosphotransferase AphA1-IAB/0.458
4kfbT27Gag-Pol polyprotein2.7.7.490.458
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
4l8u9AZSerum albumin/0.458
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.458
4n5nNAPAcetoacetyl-CoA reductase1.1.1.360.458
4rr9A3SProbable threonine--tRNA ligase 26.1.1.30.458
4ruoBIVVitamin D3 receptor A/0.458
4tqqUQ1Reaction center protein L chain/0.458
1j3jCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.457
1rgsCMPcAMP-dependent protein kinase type I-alpha regulatory subunit/0.457
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.457
2yp0OVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.457
3bgrT27Gag-Pol polyprotein2.7.7.490.457
3ft8MOJHeat shock protein HSP 90-alpha/0.457
3h1vTK1Glucokinase2.7.1.20.457
3kmyD8YBeta-secretase 13.4.23.460.457
3nx2FERFerulic acid decarboxylase/0.457
3o8hO8HHTH-type transcriptional regulator EthR/0.457
3w0gW07Vitamin D3 receptor/0.457
4gh30EVQueuine tRNA-ribosyltransferase2.4.2.290.457
4qi9MTXDihydrofolate reductase/0.457
4zj8SUVOrexin receptor type 1/0.457
2b00GCHPhospholipase A2, major isoenzyme3.1.1.40.456
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.456
2cleF6FTryptophan synthase alpha chain/0.456
2dvlFADAcyl-CoA dehydrogenase/0.456
2h94FADLysine-specific histone demethylase 1A10.456
2jfz003Glutamate racemase/0.456
2pakTYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.456
2ykbYKBHeat shock protein HSP 90-alpha/0.456
3ar5TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.456
3qpnPFKcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.456
3um61CYBifunctional dihydrofolate reductase-thymidylate synthase/0.456
3vt8YI3Vitamin D3 receptor/0.456
3w5q3KLVitamin D3 receptor/0.456
4az3S35Lysosomal protective protein3.4.16.50.456
4gg90WWQueuine tRNA-ribosyltransferase2.4.2.290.456
4iqqD16Thymidylate synthase/0.456
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.456
4pd6URINucleoside permease/0.456
4uyf73BBromodomain-containing protein 2/0.456
1jwtBLIProthrombin3.4.21.50.455
1kl2FONSerine hydroxymethyltransferase/0.455
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.455
1rc4DDFDihydrofolate reductase1.5.1.30.455
1s6qTPBGag-Pol polyprotein2.7.7.490.455
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.455
2b04CHOPhospholipase A2, major isoenzyme3.1.1.40.455
2bifANP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 42.7.1.1050.455
2ekaSAHDiphthine synthase/0.455
2zd1T27Gag-Pol polyprotein2.7.7.490.455
3hz142CHeat shock protein HSP 90-alpha/0.455
3q3cNADNAD-dependent L-serine dehydrogenase/0.455
3sh25DRDihydrofolate reductase1.5.1.30.455
3stw2TDMethylketone synthase I/0.455
3um81CYBifunctional dihydrofolate reductase-thymidylate synthase/0.455
3w0iO11Vitamin D3 receptor/0.455
3zovWZVBeta-secretase 13.4.23.460.455
4dpi0N1Beta-secretase 13.4.23.460.455
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.455
4jqh1MFAlr2278 protein/0.455
4nx6FOLDihydrofolate reductase1.5.1.30.455
5i2hAGIO-methyltransferase family 2/0.455
1eqbFFOSerine hydroxymethyltransferase2.1.2.10.454
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.454
1krv147Galactoside O-acetyltransferase2.3.1.180.454
1owmFADDeoxyribodipyrimidine photo-lyase4.1.99.30.454
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
2acwUPGGlycosyltransferase/0.454
2fa3ACOHydroxymethylglutaryl-CoA synthase/0.454
2ieaTDPPyruvate dehydrogenase E1 component1.2.4.10.454
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.454
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.454
2rgxAP5Adenylate kinase/0.454
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.454
2y6fM9FIsopenicillin N synthase1.21.3.10.454
2zfnACOHistone acetyltransferase RTT1092.3.1.480.454
3a0iAJIGlucokinase2.7.1.20.454
3c3dFO12-phospho-L-lactate transferase/0.454
3cjtSAHRibosomal protein L11 methyltransferase2.1.10.454
3dzkNMNADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.454
3e2sFADBifunctional protein PutA1.5.5.20.454
3jynNDPQuinone oxidoreductase/0.454
3o6o94MHeat shock protein 83/0.454
3tm5SFGUncharacterized protein/0.454
3w0jT08Vitamin D3 receptor/0.454
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.454
4e2yJHZMethyltransferase/0.454
4g1d0VKVitamin D3 receptor A/0.454
4g1z0VPVitamin D3 receptor A/0.454
4gkh0J9Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.454
4itfTFYVitamin D3 receptor/0.454
4v2gCTCTetracycline repressor protein class D/0.454
4x81MVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.454
5ab7MLCNonspecific lipid-transfer protein, putative/0.454
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.454
7dfrFOLDihydrofolate reductase1.5.1.30.454
1dfoFFOSerine hydroxymethyltransferase2.1.2.10.453
1diaL24C-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.453
1dlsMTXDihydrofolate reductase1.5.1.30.453
1fmlRTLRetinol dehydratase/0.453
1iiuRTLRetinol-binding protein 4/0.453
1ju6LYAThymidylate synthase2.1.1.450.453
1nceCB3Thymidylate synthase/0.453
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.453
1x2hLPALipoate-protein ligase A6.3.1.200.453
2gd0MRSProbable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )/0.453
2zlaVDBVitamin D3 receptor/0.453
3ddw055Glycogen phosphorylase, liver form2.4.1.10.453
3o4rNAPDehydrogenase/reductase SDR family member 41.1.1.1840.453
3tvxPNXcAMP-specific 3',5'-cyclic phosphodiesterase 4A3.1.4.530.453
4azwATPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.453
4bb3KKAIsopenicillin N synthase1.21.3.10.453
4c2z646Glycylpeptide N-tetradecanoyltransferase 1/0.453
4fm80UQBeta-secretase 13.4.23.460.453
4h3g10QBeta-secretase 13.4.23.460.453
4h5eYS4Farnesyl pyrophosphate synthase2.5.1.100.453
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.453
4rupH97Vitamin D3 receptor A/0.453
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.453
5cmx0G6Prothrombin3.4.21.50.453
1bq1CB3Thymidylate synthase/0.452
1dgfNDPCatalase1.11.1.60.452
1opbRETRetinol-binding protein 2/0.452
1rd4L08Integrin alpha-L/0.452
1t4u81AProthrombin3.4.21.50.452
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.452
2kceD16Thymidylate synthase/0.452
2o4jVD4Vitamin D3 receptor/0.452
2xlpNAPPutative flavin-containing monooxygenase/0.452
3adaNADSubunit alpha of sarocosine oxidase/0.452
3ebiBEYM1 family aminopeptidase3.4.110.452
3fznD7KBenzoylformate decarboxylase4.1.1.70.452
3nuyJPZ3-phosphoinositide-dependent protein kinase 12.7.11.10.452
3pyy3YYTyrosine-protein kinase ABL12.7.10.20.452
3q2mCKISpectinomycin phosphotransferase/0.452
3uic09TEnoyl-[acyl-carrier-protein] reductase [NADH]/0.452
3uxyNADShort-chain dehydrogenase/reductase SDR/0.452
3vt65YIVitamin D3 receptor/0.452
3vtcTK3Vitamin D3 receptor/0.452
3w5p4OAVitamin D3 receptor/0.452
4b3aTACTetracycline repressor protein class D/0.452
4ckrDI1Epithelial discoidin domain-containing receptor 12.7.10.10.452
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.452
4hmbPZZPhospholipase A2 VRV-PL-VIIIa/0.452
4ia1BIVVitamin D3 receptor A/0.452
4rr8A3SProbable threonine--tRNA ligase 26.1.1.30.452
5d7pOCZNAD-dependent protein deacetylase sirtuin-23.5.10.452
5hwoHMGHydroxymethylglutaryl-CoA synthase/0.452
1klmSPPGag-Pol polyprotein2.7.7.490.451
1m9k7NINitric oxide synthase, endothelial1.14.13.390.451
1owlFADDeoxyribodipyrimidine photo-lyase4.1.99.30.451
1synF89Thymidylate synthase/0.451
1umlFR4Adenosine deaminase3.5.4.40.451
2bbf344Queuine tRNA-ribosyltransferase2.4.2.290.451
2czfXMPOrotidine 5'-phosphate decarboxylase4.1.1.230.451
2dw4FADLysine-specific histone demethylase 1A10.451
2fmn4HF5,10-methylenetetrahydrofolate reductase1.5.1.200.451
2yk2YJXHeat shock protein HSP 90-alpha/0.451
3aglA03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
3c3eGDP2-phospho-L-lactate transferase/0.451
3dm6757Beta-secretase 13.4.23.460.451
3inxJZCHeat shock protein HSP 90-alpha/0.451
3itzP66Mitogen-activated protein kinase 14/0.451
3jw5TOPDihydrofolate reductase/0.451
3qlhT27Gag-Pol polyprotein2.7.7.490.451
3sqyQ11Dihydrofolate reductase1.5.1.30.451
3w0c6DSVitamin D3 receptor/0.451
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.451
3w5hFADNADH-cytochrome b5 reductase 31.6.2.20.451
4c1fX8ZMetallo-beta-lactamase type 2/0.451
4hy6FJ1Heat shock protein HSP 90-alpha/0.451
4iarERM5-hydroxytryptamine receptor 1B/0.451
4zqcF6FTryptophan synthase alpha chain/0.451
5fkkTDCTetracycline repressor protein class D/0.451
1g3mPCQEstrogen sulfotransferase2.8.2.40.450
1kmvLIIDihydrofolate reductase1.5.1.30.450
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.450
1rg7MTXDihydrofolate reductase1.5.1.30.450
1xpqFADPolyamine oxidase FMS1/0.450
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
2egsSAHDiphthine synthase/0.450
2i4tUA2Purine nucleoside phosphorylase, putative/0.450
2prh238Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.450
3cgdCOACoenzyme A disulfide reductase/0.450
3hmvHBTcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.450
3hub469Mitogen-activated protein kinase 14/0.450
3imxB84Glucokinase2.7.1.20.450
3k3iI46Mitogen-activated protein kinase 14/0.450
3mnrSD1Heat shock protein HSP 90-alpha/0.450
3srsM23Dihydrofolate reductase1.5.1.30.450
3uf6CODLmo1369 protein/0.450
3vtbTKAVitamin D3 receptor/0.450
4c49HCYCorticosteroid-binding globulin/0.450
4dpeNGHStromelysin-13.4.24.170.450
4fr10V2Queuine tRNA-ribosyltransferase2.4.2.290.450
4frkDWDBeta-secretase 13.4.23.460.450
4fsa0V3Queuine tRNA-ribosyltransferase2.4.2.290.450
4fwnAQPPropionate kinase/0.450
4gueQCTRibosomal protein S6 kinase alpha-32.7.11.10.450
4hl2ZZ7Metallo-beta-lactamase type 2/0.450
4l4xNDPAmphI/0.450
4pmjNAPPutative oxidoreductase/0.450
5c8d5ADProbable transcriptional regulator/0.450
1dxrMSTReaction center protein L chain/0.449
1h83FADPolyamine oxidase1.5.3.140.449
1jtqLY3Thymidylate synthase/0.449
1rszDIHPurine nucleoside phosphorylase2.4.2.10.449
1svlADPLarge T antigen3.6.40.449
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.449
2aazCB3Thymidylate synthase2.1.1.450.449
2bf7HBIPteridine reductase 11.5.1.330.449
2bujSTUSerine/threonine-protein kinase 16/0.449
2cjfRP43-dehydroquinate dehydratase4.2.1.100.449
2g2hP16Tyrosine-protein kinase ABL12.7.10.20.449
2hbhXE4Vitamin D3 receptor A/0.449
2io6330Wee1-like protein kinase2.7.10.20.449
2op18PCEnoyl-ACP reductase/0.449
2pmlANPUncharacterized protein/0.449
2r0pK2CPutative FAD-monooxygenase/0.449
2r7nADP5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase/0.449
2rkuR78Serine/threonine-protein kinase PLK12.7.11.210.449
2rtkGLLStreptavidin/0.449
2vcmM11Isopenicillin N synthase1.21.3.10.449
2zevB71Geranylgeranyl pyrophosphate synthase/0.449
3cgeCOACoenzyme A disulfide reductase/0.449
3ju8NADN-succinylglutamate 5-semialdehyde dehydrogenase1.2.1.710.449
3vruYS3Vitamin D3 receptor/0.449
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.449
4b5oACOAlpha-tubulin N-acetyltransferase 1/0.449
4bfuZVUPantothenate kinase2.7.1.330.449
4bfzZVZPantothenate kinase2.7.1.330.449
4e2xTYDMethyltransferase/0.449
4ea2RWZDehydrosqualene synthase/0.449
4heu15JcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.449
4i9i1DYTankyrase-12.4.2.300.449
4ia2BIVVitamin D3 receptor A/0.449
4jvj1MVFarnesyl pyrophosphate synthase2.5.1.100.449
4rraA3TProbable threonine--tRNA ligase 26.1.1.30.449
4rvuNDPProbable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein)/0.449
4tzt468Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
4ug91EWNitric oxide synthase oxygenase1.14.13.1650.449
4uy6SAHHistidine N-alpha-methyltransferase/0.449
5d7oAR6NAD-dependent protein deacetylase sirtuin-23.5.10.449
5fm7ADPRuvB-like helicase/0.449
3sn6P0GBeta-2 adrenergic receptor/0.449
1c1bGCAGag-Pol polyprotein2.7.7.490.448
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.448
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.448
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.448
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.448
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.448
2j9lATPH(+)/Cl(-) exchange transporter 5/0.448
2ji7ADPOxalyl-CoA decarboxylase4.1.1.80.448
2qxxTTPdCTP deaminase3.5.4.130.448
2uv0OHNTranscriptional activator protein LasR/0.448
2vtdLKMUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.448
2xkeWI2Serine/threonine-protein kinase Nek22.7.11.10.448
3oroAGSSerine/threonine protein kinase/0.448
3ou7SAMSAM-dependent methyltransferase/0.448
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.448
3v0o4GWHisto-blood group ABO system transferase/0.448
4a83DXCMajor pollen allergen Bet v 1-A/0.448
4fhh0U3Vitamin D3 receptor A/0.448
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4iaq2GM5-hydroxytryptamine receptor 1B/0.448
4kf1HT5Aryldialkylphosphatase3.1.8.10.448
4knzCB3Thymidylate synthase/0.448
4l9q9TPSerum albumin/0.448
4mryCEIObelin/0.448
4ubvCOASteroid 3-ketoacyl-CoA thiolase/0.448
4ykgNADAlkyl hydroperoxide reductase subunit F1.8.10.448
4z1fH71Heat shock protein 75 kDa, mitochondrial/0.448
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.448
5ai5BSUBifunctional epoxide hydrolase 23.1.3.760.448
5jr34MUCarminomycin 4-O-methyltransferase DnrK2.1.1.2920.448
1d8fSPIStromelysin-13.4.24.170.447
1fkxPRHAdenosine deaminase3.5.4.40.447
1fw0KAIGlutamate receptor 2/0.447
1poxFADPyruvate oxidase1.2.3.30.447
1q63AIQQueuine tRNA-ribosyltransferase2.4.2.290.447
1s3uTQDDihydrofolate reductase1.5.1.30.447
1s4eADPGalactokinase/0.447
1w7kADPDihydrofolate synthase/folylpolyglutamate synthase6.3.2.120.447
1x8b824Wee1-like protein kinase2.7.10.20.447
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.447
2cduADPNADH oxidase/0.447
2ewpTXFEstrogen-related receptor gamma/0.447
2hcdBIVVitamin D3 receptor A/0.447
2hwrDRDPeroxisome proliferator-activated receptor gamma/0.447
2iwuNP5ATP-dependent molecular chaperone HSP82/0.447
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.447
2ol4JPNEnoyl-ACP reductase/0.447
2ovyPFJcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.447
2v5zSAGAmine oxidase [flavin-containing] B1.4.3.40.447
2x7hPFNProstaglandin reductase 310.447
2xiyXIYSerine/threonine-protein kinase pim-12.7.11.10.447
3bw3FMNPutative 2-nitropropane dioxygenase/0.447
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.447
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.447
3hz137DHeat shock protein HSP 90-alpha/0.447
3lz6A0DCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.447
3reoSAH(Iso)eugenol O-methyltransferase2.1.1.1460.447
3up3XCAaceDAF-12/0.447
3zze6XPHepatocyte growth factor receptor2.7.10.10.447
4cj4S3GIntegrase/0.447
4g34924Eukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.447
4ii5ADPCyclin-dependent kinase 22.7.11.220.447
4rujVDXVitamin D3 receptor A/0.447
5uviZMAAdenosine receptor A2a/0.447
1cgkNARChalcone synthase 22.3.1.740.446
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.446
1flmFMNFMN-binding protein/0.446
1g93UPGN-acetyllactosaminide alpha-1,3-galactosyltransferase/0.446
1jtuLYBThymidylate synthase/0.446
1osvCHCBile acid receptor/0.446
1rq1FADEndoplasmic oxidoreductin-11.8.40.446
1trkTPPTransketolase 12.2.1.10.446
1ux0THUCytidine deaminase3.5.4.50.446
1uymPU3Heat shock protein HSP 90-beta/0.446
1w19T1P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.446
2fhjMFNFormylmethanofuran--tetrahydromethanopterin formyltransferase2.3.1.1010.446
2qo9ANPEphrin type-A receptor 32.7.10.10.446
2vd5BI8Myotonin-protein kinase2.7.11.10.446
2zynBCDPeriplasmic binding protein/0.446
3a1l2CCCytochrome P450/0.446
3cid318Beta-secretase 13.4.23.460.446
3exo5MSBeta-secretase 13.4.23.460.446
3fhxPLPPyridoxal kinase2.7.1.350.446
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.446
3qh23NMThiazole tautomerase/0.446
3sm0AEKQueuine tRNA-ribosyltransferase2.4.2.290.446
3udq09EBeta-secretase 13.4.23.460.446
3ujlA8SAbscisic acid receptor PYL2/0.446
3vrwYS5Vitamin D3 receptor/0.446
4at0FADPossible succinate dehydrogenase/0.446
4b70WM9Beta-secretase 13.4.23.460.446
4f0rMTA5-methylthioadenosine/S-adenosylhomocysteine deaminase/0.446
4fhi0S4Vitamin D3 receptor A/0.446
4oztP1AEcdysone receptor, putative/0.446
4qerSTLPhospholipase A2 VRV-PL-VIIIa/0.446
4u8iFDAUDP-galactopyranose mutase/0.446
4uofDATNucleoside diphosphate kinase/0.446
5aqzSGVHeat shock 70 kDa protein 1A/0.446
5c7hNDPPutative oxidoreductase/0.446
5iqaGNPBifunctional AAC/APH2.3.10.446
1ek2CDUBifunctional epoxide hydrolase 2/0.445
1h36R88Squalene--hopene cyclase4.2.1.1290.445
1icpFMN12-oxophytodienoate reductase 11.3.1.420.445
1jlcFTCGag-Pol polyprotein2.7.7.490.445
1nzq162Prothrombin3.4.21.50.445
1tdrMTXDihydrofolate reductase1.5.1.30.445
1v08NTZ4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic3.2.1.1820.445
1v7aFRCAdenosine deaminase3.5.4.40.445
1w29TS06,7-dimethyl-8-ribityllumazine synthase2.5.1.780.445
1x8lOXRRetinol dehydratase/0.445
1xdkREARetinoic acid receptor beta/0.445
1ygjRMCPyridoxal kinase2.7.1.350.445
1zprCB3Thymidylate synthase/0.445
2clfF6FTryptophan synthase alpha chain/0.445
2ix5FADAcyl-coenzyme A oxidase 4, peroxisomal1.3.3.60.445
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.445
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.445
2ofv242Tyrosine-protein kinase Lck2.7.10.20.445
2vfzUPFN-acetyllactosaminide alpha-1,3-galactosyltransferase/0.445
2wkyIBCGlutamate receptor ionotropic, kainate 1/0.445
2x21PIDPeridinin-chlorophyll a-binding protein 1, chloroplastic/0.445
2yfeYFEPeroxisome proliferator-activated receptor gamma/0.445
2z2w770Wee1-like protein kinase2.7.10.20.445
3ansS38Bifunctional epoxide hydrolase 23.3.2.100.445
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.445
3hxeBD8Geranylgeranyl transferase type-2 subunit beta2.5.1.600.445
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.445
3kytHC2Nuclear receptor ROR-gamma/0.445
3mb714ICasein kinase II subunit alpha2.7.11.10.445
3vw8DF6Hepatocyte growth factor receptor2.7.10.10.445
3w0aDS5Vitamin D3 receptor/0.445
3zkuHCVIsopenicillin N synthase1.21.3.10.445
4aacAAVMitogen-activated protein kinase 14/0.445
4aqlTXCGuanine deaminase3.5.4.30.445
4hvs647Mast/stem cell growth factor receptor Kit2.7.10.10.445
4i8vBHFCytochrome P450 1A11.14.14.10.445
4iwv1J9Glucokinase2.7.1.20.445
4j0p1H8Beta-secretase 13.4.23.460.445
4m4821BSodium-dependent dopamine transporter/0.445
4rrgA3TThreonine--tRNA ligase6.1.1.30.445
4xivACPChemotaxis protein CheA2.7.13.30.445
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.445
4n4wSNTSmoothened homolog/0.445
1f28F89Thymidylate synthase2.1.1.450.444
1f4gTP4Thymidylate synthase/0.444
1j3iWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.444
1qv1CZHObelin/0.444
1typNAPTrypanothione reductase1.8.1.120.444
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.444
1w1rZEACytokinin dehydrogenase 11.5.99.120.444
1xzqFONtRNA modification GTPase MnmE3.6.50.444
1y5xE89Queuine tRNA-ribosyltransferase2.4.2.290.444
1zdwFLVPrenyltransferase/0.444
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.444
2fwyH64Heat shock protein HSP 90-alpha/0.444
2iyiFMNAppA, antirepressor of ppsR, sensor of blue light/0.444
2jc6QPPCalcium/calmodulin-dependent protein kinase type 1D2.7.11.170.444
2jfhLK1UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.444
2mokFMNFlavodoxin 1/0.444
2pchSAHDiphthine synthase/0.444
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.444
2po7CHDFerrochelatase, mitochondrial4.99.1.10.444
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.444
2xiq5ADMethylmalonyl-CoA mutase, mitochondrial/0.444
3c1xCKKHepatocyte growth factor receptor2.7.10.10.444
3f4bTCLEnoyl-acyl carrier protein reductase/0.444
3gkiCLRNiemann-Pick C1 protein/0.444
3hl7I46Mitogen-activated protein kinase 14/0.444
3ixj586Beta-secretase 13.4.23.460.444
3llaACPMyosin heavy chain kinase A2.7.11.70.444
3qgd26SGenome polyprotein2.7.7.480.444
3r8gIZPAldo-keto reductase family 1 member C3/0.444
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.444
3vgwNVZAvidin/0.444
3vt45YIVitamin D3 receptor/0.444
3zswZSWIntegrase/0.444
4b7754MBeta-secretase 13.4.23.460.444
4bb2STRCorticosteroid-binding globulin/0.444
4bdrKAIGlutamate receptor ionotropic, kainate 2/0.444
4caxMYAGlycylpeptide N-tetradecanoyltransferase2.3.1.970.444
4ia7BIVVitamin D3 receptor A/0.444
4k4eK4ETankyrase-12.4.2.300.444
4muw2F4cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
4q8pCKRQueuine tRNA-ribosyltransferase2.4.2.290.444
4r81FMNPredicted NADH dehydrogenase/0.444
4x7vMIVMycinamicin III 3''-O-methyltransferase2.1.1.2370.444
5ab6CAANonspecific lipid-transfer protein, putative/0.444
5dv2C5PCCR4-NOT transcription complex subunit 6-like3.1.13.40.444
5kf8ACOPredicted acetyltransferase/0.444
5jtbZMAAdenosine receptor A2a/0.444
1blzACVIsopenicillin N synthase1.21.3.10.443
1ci7CB3Thymidylate synthase2.1.1.450.443
1dyrTOPDihydrofolate reductase1.5.1.30.443
1kt6RTLRetinol-binding protein 4/0.443
1n5sADLActVA 6 protein/0.443
1nbhSAMGlycine N-methyltransferase2.1.1.200.443
1ndzFR5Adenosine deaminase3.5.4.40.443
1ozqPRFQueuine tRNA-ribosyltransferase2.4.2.290.443
1t0iFMNNAD(P)H-dependent FMN reductase LOT6/0.443
1txtCAAHMG-CoA synthase/0.443
1z5uCMPClass B acid phosphatase/0.443
1zq5E04Aldo-keto reductase family 1 member C3/0.443
2b4rNADGlyceraldehyde-3-phosphate dehydrogenase/0.443
2bxaC1FSerum albumin/0.443
2bxqIMNSerum albumin/0.443
2c29NAPDihydroflavonol 4-reductase/0.443
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.443
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.443
2ftoTMPThymidylate synthase/0.443
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.443
2op07PCEnoyl-ACP reductase/0.443
2p6dSAHDiphthine synthase/0.443
2v00V15Endothiapepsin3.4.23.220.443
2vkeTACTetracycline repressor protein class D/0.443
3axwTIDCasein kinase II subunit alpha2.7.11.10.443
3cib314Beta-secretase 13.4.23.460.443
3dndLL2cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
3h0bB35Beta-secretase 13.4.23.460.443
3h3r14HCollagen type IV alpha-3-binding protein/0.443
3ntdFADFAD-dependent pyridine nucleotide-disulphide oxidoreductase/0.443
3um5CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.443
3vrvYSDVitamin D3 receptor/0.443
3zkyWT4Isopenicillin N synthase1.21.3.10.443
3zxhE41Collagenase 33.4.240.443
4awo99BHeat shock protein HSP 90-alpha/0.443
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.443
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.443
4eftEFTHeat shock protein HSP 90-alpha/0.443
4eilFOLBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.443
4ekl0RFRAC-alpha serine/threonine-protein kinase2.7.11.10.443
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.443
4fklCK2Cyclin-dependent kinase 22.7.11.220.443
4fw05KJNitric oxide synthase, brain1.14.13.390.443
4go2TAPCytosolic 10-formyltetrahydrofolate dehydrogenase1.5.1.60.443
4h1m0YJProtein-tyrosine kinase 2-beta2.7.10.20.443
4hkfACOAlpha-tubulin N-acetyltransferase 1/0.443
4hnc0UTMandelate racemase/0.443
4k9nTZDBenzoylformate decarboxylase4.1.1.70.443
4mm729JNa(+):neurotransmitter symporter (Snf family)/0.443
4mm9FVXNa(+):neurotransmitter symporter (Snf family)/0.443
4o95245Cytokinin dehydrogenase 4/0.443
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.443
5jr3SAHCarminomycin 4-O-methyltransferase DnrK2.1.1.2920.443
1a80NDP2,5-diketo-D-gluconic acid reductase A1.1.1.3460.442
1crbRTLRetinol-binding protein 1/0.442
1hwlADP3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.442
1jjeBYSBeta-lactamase/0.442
1me7RVPInosine-5'-monophosphate dehydrogenase/0.442
1nzdUPGDNA beta-glucosyltransferase/0.442
1rftPXMPyridoxal kinase2.7.1.350.442
1tj1FADBifunctional protein PutA1.5.5.20.442
1ve3SAMUncharacterized protein/0.442
1yq7RISFarnesyl pyrophosphate synthase2.5.1.100.442
1zz1SHHHistone deacetylase-like amidohydrolase3.5.10.442
2a8gGNGAvidin/0.442
2aibERGBeta-elicitin cinnamomin/0.442
2bgjFADNADPH:ferredoxin reductase/0.442
2rhrEMOPutative ketoacyl reductase1.3.10.442
2tctCTCTetracycline repressor protein class D/0.442
2uuk897Prothrombin3.4.21.50.442
2vbdV10Isopenicillin N synthase1.21.3.10.442
2x7jTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.442
2xpuTDCTetracycline repressor protein class D/0.442
2ym2NAPPhenylacetone monooxygenase1.14.13.920.442
3fknFKNMitogen-activated protein kinase 14/0.442
3fne8PCEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.442
3jsuKA5Bifunctional dihydrofolate reductase-thymidylate synthase/0.442
3n6mGTPGenome polyprotein/0.442
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
3sfi3SFHTH-type transcriptional regulator EthR/0.442
3zhyFM61-deoxy-D-xylulose 5-phosphate reductoisomerase/0.442
3zsh469Mitogen-activated protein kinase 14/0.442
4a51ADPKinesin-like protein KIF11/0.442
4a87NARMajor pollen allergen Bet v 1-A/0.442
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
4cgiNZLIntegrase/0.442
4dvi2IWTankyrase-12.4.2.300.442
4feu537Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.442
4jk3NADUncharacterized protein/0.442
4jlm1NNDeoxycytidine kinase2.7.1.740.442
4l23X6KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.442
4lc71WPBeta-secretase 13.4.23.460.442
4n3r2GUTankyrase-12.4.2.300.442
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.442
4xba5GPAprataxin-like protein30.442
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.442
5k2aZMAAdenosine receptor A2a/0.442
1bk0ACVIsopenicillin N synthase1.21.3.10.441
1bucFADAcyl-CoA dehydrogenase, short-chain specific1.3.8.10.441
1bx6BA1cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
1d3dBZTProthrombin3.4.21.50.441
1j8uH4BPhenylalanine-4-hydroxylase1.14.16.10.441
1mfzGDXGDP-mannose 6-dehydrogenase1.1.1.1320.441
1ndyFR3Adenosine deaminase3.5.4.40.441
1ne6SP1cAMP-dependent protein kinase type I-alpha regulatory subunit/0.441
1ppjANYCytochrome b/0.441
1rx2FOLDihydrofolate reductase1.5.1.30.441
1sriDMBStreptavidin/0.441
1tw2ERTCarminomycin 4-O-methyltransferase DnrK2.1.1.2920.441
1uzeEALAngiotensin-converting enzyme3.2.10.441
2az3CDPNucleoside diphosphate kinase/0.441
2eleSAHDiphthine synthase/0.441
2evcFC3Methionine aminopeptidase/0.441
2fhlBNIAvidin-related protein 4/5/0.441
2fpcSCGStrictosidine synthase4.3.3.20.441
2gs9SAHUncharacterized protein/0.441
2hctNMNADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.441
2ociTYCValacyclovir hydrolase3.10.441
2vmyFFOSerine hydroxymethyltransferase/0.441
2w3mFOLDihydrofolate reductase1.5.1.30.441
2wyaHMGHydroxymethylglutaryl-CoA synthase, mitochondrial2.3.3.100.441
2x1hX1HProstaglandin reductase 310.441
3apwDP0Alpha-1-acid glycoprotein 2/0.441
3dmjGWEPol protein/0.441
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.441
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.441
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
3h3t16HCollagen type IV alpha-3-binding protein/0.441
3nu03TUDihydrofolate reductase1.5.1.30.441
3pe2E1BCasein kinase II subunit alpha2.7.11.10.441
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.441
3v4aPK1Androgen receptor/0.441
3w0uHPWLactoylglutathione lyase4.4.1.50.441
3zy5GFBGDP-fucose protein O-fucosyltransferase 12.4.1.2210.441
4a6bQG8Gag-Pol polyprotein3.4.23.160.441
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.441
4c5bADPD-alanine--D-alanine ligase B6.3.2.40.441
4edy9PQHematopoietic prostaglandin D synthase/0.441
4g2h0VQVitamin D3 receptor A/0.441
4geb0LDKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.441
4iq71G9Mycocyclosin synthase1.14.21.90.441
4jvlESTEstrogen sulfotransferase2.8.2.40.441
4k0bSAMS-adenosylmethionine synthase/0.441
4pl9ADPEthylene receptor 1/0.441
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.441
4wx2F6FTryptophan synthase alpha chain/0.441
4wx2F6FTryptophan synthase beta chain4.2.1.200.441
4z07PCGcGMP-dependent protein kinase 12.7.11.120.441
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.441
3uzcT4EAdenosine receptor A2a/0.441
1bxrANPCarbamoyl-phosphate synthase large chain/0.440
1khrCOAStreptogramin A acetyltransferase2.3.10.440
1oc1ASVIsopenicillin N synthase1.21.3.10.440
1orkATCTetracycline repressor protein class D/0.440
1oynROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
1qorNDPQuinone oxidoreductase 1/0.440
1tvcFDAMethane monooxygenase component C1.14.13.250.440
1xf0ASDAldo-keto reductase family 1 member C3/0.440
2a4xBLMMitomycin-binding protein/0.440
2bglNAJSecoisolariciresinol dehydrogenase1.1.1.3310.440
2iko7IGRenin3.4.23.150.440
2wnbC5PCMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 12.4.99.40.440
2y53NAP3,4-dehydroadipyl-CoA semialdehyde dehydrogenase/0.440
3aivHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic3.2.1.1820.440
3anlSYC1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.440
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
3naxMP73-phosphoinositide-dependent protein kinase 12.7.11.10.440
3nugNADPyridoxal 4-dehydrogenase1.1.1.1070.440
3oibFDAPutative acyl-CoA dehydrogenase/0.440
3tx1FADUDP-N-acetylenolpyruvoylglucosamine reductase/0.440
3u8w09JMitogen-activated protein kinase 14/0.440
3wb40B3Beta-secretase 13.4.23.460.440
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
4bwaN0BPyrrolysine--tRNA ligase/0.440
4do30LAFatty-acid amide hydrolase 13.5.1.990.440
4fwjFADLysine-specific histone demethylase 1B10.440
4gdpFADPolyamine oxidase FMS1/0.440
4gtv7TRGeranylgeranyl transferase type-2 subunit beta2.5.1.600.440
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.440
4jp91M5Beta-secretase 13.4.23.460.440
4jvnYUGEstrogen sulfotransferase2.8.2.40.440
4m6kFOLDihydrofolate reductase1.5.1.30.440
4v010LIFibroblast growth factor receptor 1 (Fms-related tyrosine kinase 2, Pfeiffer syndrome), isoform CRA_b/0.440
4x28FDAAcyl-CoA dehydrogenase FadE26/0.440
4x28FDAAcyl-CoA dehydrogenase FadE27/0.440
5c4fUPGHisto-blood group ABO system transferase/0.440
5cvcPLPSerine racemase/0.440
5fbhTCRExtracellular calcium-sensing receptor/0.440