sc-PDB

List of CHEMBLId :

This value allows a number of roughly comparable measures of half-maximal response concentration/potency/affinity to be compared on a negative logarithmic scale (e.g., an IC50 measurement of 1nM would have a pChEMBL value of 9).

Uniprot Annotation

Name:	Orotidine 5'-phosphate decarboxylase
ID:	PYRF_PYRHO
AC:	O58462
Organism:	Pyrococcus horikoshii
Reign:	Archaea
TaxID:	70601
EC Number:	4.1.1.23

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Chains:

Chain Name:	Percentage of Residues within binding site
A	18 %
B	82 %

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Ligand binding site composition:

B-Factor:	24.443
Number of residues:	33
Including
Standard Amino Acids:	28
Non Standard Amino Acids:	0
Water Molecules:	5
Cofactors:
Metals:

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Cavity properties

Ligandability	Volume (Å3)
0.498	597.375

% Hydrophobic	% Polar
40.11	59.89
According to VolSite

HET Code:	XMP
Formula:	C10H11N4O9P
Molecular weight:	362.190 g/mol
DrugBank ID:	DB02309
Buried Surface Area:	57.07 %
Polar Surface area:	207.94 Å2

Number of
H-Bond Acceptors:	10
H-Bond Donors:	4
Rings:	3
Aromatic rings:	1
Anionic atoms:	2
Cationic atoms:	0
Rule of Five Violation:	1
Rotatable Bonds:	4

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Mass center Coordinates

X	Y	Z
-3.66212	-9.90487	30.1668

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