sc-PDB

List of CHEMBLId :

This value allows a number of roughly comparable measures of half-maximal response concentration/potency/affinity to be compared on a negative logarithmic scale (e.g., an IC50 measurement of 1nM would have a pChEMBL value of 9).

Uniprot Annotation

Name:	Tryptophan--tRNA ligase, cytoplasmic
ID:	SYWC_YEAST
AC:	Q12109
Organism:	Saccharomyces cerevisiae
Reign:	Eukaryota
TaxID:	559292
EC Number:	6.1.1.2

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Chains:

Chain Name:	Percentage of Residues within binding site
A	100 %

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Ligand binding site composition:

B-Factor:	71.974
Number of residues:	23
Including
Standard Amino Acids:	23
Non Standard Amino Acids:	0
Water Molecules:	0
Cofactors:
Metals:

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Cavity properties

Ligandability	Volume (Å3)
1.112	1326.375

% Hydrophobic	% Polar
33.08	66.92
According to VolSite

HET Code:	LTN
Formula:	C11H14N3O
Molecular weight:	204.248 g/mol
DrugBank ID:	DB04537
Buried Surface Area:	71.31 %
Polar Surface area:	86.52 Å2

Number of
H-Bond Acceptors:	1
H-Bond Donors:	3
Rings:	2
Aromatic rings:	2
Anionic atoms:	0
Cationic atoms:	1
Rule of Five Violation:	0
Rotatable Bonds:	3

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Mass center Coordinates

X	Y	Z
-96.6005	121.319	-13.5295

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