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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1stoOMPOrotate phosphoribosyltransferase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1stoOMPOrotate phosphoribosyltransferase/1.000
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.520
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.517
4fhd0TTSpore photoproduct lyase/0.516
2hkoFADLysine-specific histone demethylase 1A10.515
3ungADPCRISPR system Cmr subunit Cmr2/0.514
1g8oU5PN-acetyllactosaminide alpha-1,3-galactosyltransferase/0.509
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.508
3lfzADPUncharacterized protein MJ1225/0.505
3tptADPSerine/threonine-protein kinase toxin HipA/0.500
4ap7F47Hepatocyte growth factor receptor2.7.10.10.499
1l8tADPAminoglycoside 3'-phosphotransferase2.7.1.950.497
2wgjVGHHepatocyte growth factor receptor2.7.10.10.497
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.494
4fhf0TTSpore photoproduct lyase/0.494
3bi2FADPolyamine oxidase FMS1/0.493
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.493
1z6lFADPolyamine oxidase FMS1/0.492
3l06SN0N-acetylornithine carbamoyltransferase2.1.3.90.492
4gg70J8Hepatocyte growth factor receptor2.7.10.10.492
3b5iSAHIndole-3-acetate O-methyltransferase 1/0.491
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.490
3biz61EWee1-like protein kinase2.7.10.20.490
3q2jCKIAminoglycoside 3'-phosphotransferase2.7.1.950.488
3bbfGDPNucleoside diphosphate kinase B2.7.4.60.487
3gcq1BUMitogen-activated protein kinase 14/0.487
4bfrJ82Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform2.7.1.1530.487
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.486
2puiADPMethylthioribose kinase2.7.1.1000.486
1e96GTPRas-related C3 botulinum toxin substrate 1/0.485
4a39GEMUncharacterized protein/0.485
4uy6SAHHistidine N-alpha-methyltransferase/0.485
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.484
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.484
4gdpFADPolyamine oxidase FMS1/0.483
4tx9AMZPhosphoribosyl isomerase A/0.483
5jtbZMAAdenosine receptor A2a/0.483
3emlZMAAdenosine receptor A2a/0.483
1ve3SAMUncharacterized protein/0.482
3kzoAN0N-acetylornithine carbamoyltransferase2.1.3.90.482
3zxzKRWHepatocyte growth factor receptor2.7.10.10.482
4gurFADLysine-specific histone demethylase 1B10.482
4rh10TTSpore photoproduct lyase/0.482
5k2aZMAAdenosine receptor A2a/0.482
3q6jKPC2-oxopropyl-CoM reductase, carboxylating1.8.1.50.481
4ai8DZAHypoxia-inducible factor 1-alpha inhibitor1.14.11.300.481
4qtuSAM18S rRNA (guanine(1575)-N(7))-methyltransferase/0.481
1nd52BFProstatic acid phosphatase3.1.3.20.480
1rzuADPGlycogen synthase 12.4.1.210.480
3iw4LW4Protein kinase C alpha type2.7.11.130.480
3n0yAPCAdenylate cyclase 2/0.480
3zc5W9ZHepatocyte growth factor receptor2.7.10.10.480
4pkwGM6Lethal factor3.4.24.830.480
1hfqMOTDihydrofolate reductase1.5.1.30.479
2ojg19AMitogen-activated protein kinase 12.7.11.240.479
4dlsGNPGTPase HRas/0.479
4gk3L87Ephrin type-A receptor 32.7.10.10.479
5k2cZMAAdenosine receptor A2a/0.479
4equG6ISerine/threonine-protein kinase 102.7.11.10.478
1f8gNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.477
1s3uTQDDihydrofolate reductase1.5.1.30.477
2ea4F79Methionine aminopeptidase 2/0.477
3nxvD2FDihydrofolate reductase1.5.1.30.477
4c6zTLE3-oxoacyl-ACP synthase/0.477
1kdkDHTSex hormone-binding globulin/0.476
2fm0M98cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.476
3cqeP91Wee1-like protein kinase2.7.10.20.476
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.476
4kq21S3Glycogen [starch] synthase isoform 22.4.1.110.476
5hpyGDPTransforming protein RhoA/0.476
1csnATPCasein kinase I homolog 12.7.11.10.475
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.475
2bfmTOPPteridine reductase 11.5.1.330.475
2qbr910Tyrosine-protein phosphatase non-receptor type 13.1.3.480.475
2y882ERPhosphoribosyl isomerase A5.3.1.160.475
4giy0WYQueuine tRNA-ribosyltransferase2.4.2.290.475
4gqkADPActin cross-linking toxin VgrG1/0.475
4kq2U5PGlycogen [starch] synthase isoform 22.4.1.110.475
1stdBFSScytalone dehydratase4.2.1.940.474
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.474
2bhiSFTCytotoxin 3/0.474
2j9lATPH(+)/Cl(-) exchange transporter 5/0.474
3cgyRDCVirulence sensor histidine kinase PhoQ2.7.13.30.474
3dhcCYKN-acyl homoserine lactonase AiiA3.1.1.810.474
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.474
3nn6HNK6-hydroxy-L-nicotine oxidase/0.474
3nxyD2HDihydrofolate reductase1.5.1.30.474
4aoi4K0Hepatocyte growth factor receptor2.7.10.10.474
4bgbADPPredicted molecular chaperone distantly related to HSP70-fold metalloproteases/0.474
4nm9FADBifunctional protein PutA/0.474
2bakAQZMitogen-activated protein kinase 14/0.473
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.473
2ovvPFHcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.473
2rgcGNPGTPase HRas/0.473
2wkyIBCGlutamate receptor ionotropic, kainate 1/0.473
3pghFLPProstaglandin G/H synthase 21.14.99.10.473
4a9yAQZMitogen-activated protein kinase 14/0.473
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.473
4f3gKAIGlutamate receptor 3/0.473
4lzwTHMUridine phosphorylase/0.473
2bt4CA23-dehydroquinate dehydratase4.2.1.100.472
2oscMUHAngiopoietin-1 receptor2.7.10.10.472
3qakUKAAdenosine receptor A2a/0.472
1ozqPRFQueuine tRNA-ribosyltransferase2.4.2.290.471
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.471
1vhnFMNtRNA-dihydrouridine synthase/0.471
1w2cANPInositol-trisphosphate 3-kinase A2.7.1.1270.471
2p2lGDPRas-related C3 botulinum toxin substrate 1/0.471
3g0cRUFDipeptidyl peptidase 4/0.471
3nxtD2EDihydrofolate reductase1.5.1.30.471
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.471
4gg50J3Hepatocyte growth factor receptor2.7.10.10.471
4uohADPNucleoside diphosphate kinase/0.471
5iua6DXAdenosine receptor A2a/0.471
1gpeFADGlucose oxidase1.1.3.40.470
3sl2ATPSensor histidine kinase WalK/0.470
3zbx6XEHepatocyte growth factor receptor2.7.10.10.470
5iu86DZAdenosine receptor A2a/0.470
1cqp803Integrin alpha-L/0.469
2b8jADNClass B acid phosphatase3.1.3.20.469
3c3eFO12-phospho-L-lactate transferase/0.469
3keqNADRedox-sensing transcriptional repressor Rex/0.469
3sgy06WDihydrofolate reductase1.5.1.30.469
3x03ANPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1490.469
4kc2WS2Histo-blood group ABO system transferase/0.469
4kd79DRDihydrofolate reductase1.5.1.30.469
4xbfFADLysine-specific histone demethylase 1A10.469
3uzaT4GAdenosine receptor A2a/0.469
1dr4HBIDihydrofolate reductase1.5.1.30.468
1ia9ANPTransient receptor potential cation channel subfamily M member 72.7.11.10.468
1mo9KPC2-oxopropyl-CoM reductase, carboxylating1.8.1.50.468
1n5vNOMActVA 6 protein/0.468
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.468
2acxANPG protein-coupled receptor kinase 62.7.11.160.468
2cjfRP43-dehydroquinate dehydratase4.2.1.100.468
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.468
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.468
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.468
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.468
3l034OHEstrogen receptor/0.468
3lcjCOAPhosphopantetheine adenylyltransferase/0.468
3qge26FGenome polyprotein2.7.7.480.468
4gh10WXQueuine tRNA-ribosyltransferase2.4.2.290.468
4hsuFADLysine-specific histone demethylase 1B10.468
4koxCLSUncharacterized protein/0.468
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.467
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.467
3h4vDVPPteridine reductase 11.5.1.330.467
4eb4D16Thymidylate synthase2.1.1.450.467
4h6pFMNChromate reductase/0.467
1fdkGLEPhospholipase A23.1.1.40.466
1rgsCMPcAMP-dependent protein kinase type I-alpha regulatory subunit/0.466
1u1f183Uridine phosphorylase2.4.2.30.466
2in6839Wee1-like protein kinase2.7.10.20.466
2potGUNQueuine tRNA-ribosyltransferase2.4.2.290.466
3b6pTMPThree-prime repair exonuclease 13.1.11.20.466
3djfBC3Purine nucleoside phosphorylase/0.466
3g7fUQ1Reaction center protein L chain/0.466
3negPYVAbscisic acid receptor PYL1/0.466
3p1799PProthrombin3.4.21.50.466
4bewACPSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.466
4j521J3Serine/threonine-protein kinase PLK12.7.11.210.466
4kttSAMS-adenosylmethionine synthase isoform type-22.5.1.60.466
4pl9ADPEthylene receptor 1/0.466
4rkfGNPRas-related protein Rab-3/0.466
5dgzL20Serine/threonine-protein kinase pim-12.7.11.10.466
5fd8A5APutative carboxypeptidase yocD/0.466
1crbRTLRetinol-binding protein 1/0.465
1k4hAPQQueuine tRNA-ribosyltransferase2.4.2.290.465
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
2v59LZKBiotin carboxylase6.3.4.140.465
2xlrNAPPutative flavin-containing monooxygenase/0.465
3d3p20AcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.465
3l05SN0N-acetylornithine carbamoyltransferase2.1.3.90.465
4fj0HHF17beta-hydroxysteroid dehydrogenase/0.465
4ndnSAMS-adenosylmethionine synthase isoform type-22.5.1.60.465
4nyjGNPGTPase HRas/0.465
1mznBM6Retinoic acid receptor RXR-alpha/0.464
1xddAAYIntegrin alpha-L/0.464
2nnqT4BFatty acid-binding protein, adipocyte/0.464
2olcADPMethylthioribose kinase2.7.1.1000.464
3k7mFAD6-hydroxy-L-nicotine oxidase/0.464
3rs7GNPGTPase HRas/0.464
3srsM23Dihydrofolate reductase1.5.1.30.464
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.464
4f1oACPProbable serine/threonine-protein kinase roco42.7.11.10.464
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.464
4gr9372Ribosyldihydronicotinamide dehydrogenase [quinone]/0.464
4tzt468Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.464
5dw50T1Succinyl-CoA:acetate CoA-transferase/0.464
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.463
2wkmPFYHepatocyte growth factor receptor2.7.10.10.463
3ae4FADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.463
3l8yGNPGTPase HRas/0.463
4eixNIMPhospholipase A2 VRV-PL-VIIIa/0.463
4gt8ADPSensor protein VraS2.7.13.30.463
4i1nFOLDihydrofolate reductase1.5.1.30.463
4obeGDPGTPase KRas/0.463
5k2bZMAAdenosine receptor A2a/0.463
1dtnAPGMandelate racemase/0.462
1efaNPFLactose operon repressor/0.462
1snuSTUTyrosine-protein kinase ITK/TSK2.7.10.20.462
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.462
2a19ANPInterferon-induced, double-stranded RNA-activated protein kinase2.7.11.10.462
2g1m4HGEgl nine homolog 1/0.462
2ghlLIBMitogen-activated protein kinase 14/0.462
2iyiFMNAppA, antirepressor of ppsR, sensor of blue light/0.462
2z2w770Wee1-like protein kinase2.7.10.20.462
3fufBESLeukotriene A-4 hydrolase3.3.2.60.462
3gc4AAQQueuine tRNA-ribosyltransferase2.4.2.290.462
3juqAJDPhenazine biosynthesis protein A/B/0.462
3lfeZ84Mitogen-activated protein kinase 14/0.462
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.462
3q9wEMOCasein kinase II subunit alpha2.7.11.10.462
4fweFADLysine-specific histone demethylase 1B10.462
1e26GPBDihydrofolate reductase1.5.1.30.461
1hfpMOTDihydrofolate reductase1.5.1.30.461
1k4gAIQQueuine tRNA-ribosyltransferase2.4.2.290.461
1kdmDHTSex hormone-binding globulin/0.461
1u1d181Uridine phosphorylase2.4.2.30.461
2b1z17MEstrogen receptor/0.461
2o8h227cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.461
2poqISDTrans-1,2-dihydrobenzene-1,2-diol dehydrogenase1.3.1.200.461
2xauADPPre-mRNA-splicing factor ATP-dependent RNA helicase PRP433.6.4.130.461
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
3iktNADRedox-sensing transcriptional repressor Rex/0.461
3qpnPFKcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.461
3qpoPFRcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.461
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.461
4gncASORegucalcin3.1.1.170.461
4kc1WS1Histo-blood group ABO system transferase/0.461
4kfj1R0Dihydrofolate reductase1.5.1.30.461
4l9wGNPGTPase HRas/0.461
5k2dZMAAdenosine receptor A2a/0.461
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
1ltzHBIPhenylalanine-4-hydroxylase1.14.16.10.460
1q9mROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.460
1s3wTQTDihydrofolate reductase1.5.1.30.460
1tkxGWBGag-Pol polyprotein2.7.7.490.460
1towCRZFatty acid-binding protein, adipocyte/0.460
1z2cGNPRho-related GTP-binding protein RhoC/0.460
2g78REACellular retinoic acid-binding protein 2/0.460
2xxvKAIGlutamate receptor ionotropic, kainate 2/0.460
3k47D09Dihydrofolate reductase1.5.1.30.460
3tfn2CJDehydrosqualene synthase/0.460
3tvxPNXcAMP-specific 3',5'-cyclic phosphodiesterase 4A3.1.4.530.460
3uhmRFNUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.460
4o4fATPKinase/0.460
1i2lDCSAminodeoxychorismate lyase4.1.3.380.459
1i59ANPChemotaxis protein CheA2.7.13.30.459
1iayAVG1-aminocyclopropane-1-carboxylate synthase 24.4.1.140.459
1kt3RTLRetinol-binding protein 4/0.459
1p33MTXPteridine reductase 11.5.1.330.459
1qzfFOLBifunctional dihydrofolate reductase-thymidylate synthase/0.459
1uwhBAXSerine/threonine-protein kinase B-raf2.7.11.10.459
1y5xE89Queuine tRNA-ribosyltransferase2.4.2.290.459
2h94FADLysine-specific histone demethylase 1A10.459
2j5xGSPADP-ribosylation factor 6/0.459
2jc6QPPCalcium/calmodulin-dependent protein kinase type 1D2.7.11.170.459
2ncdADPProtein claret segregational/0.459
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.459
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.459
3aivHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic3.2.1.1820.459
3dfrMTXDihydrofolate reductase1.5.1.30.459
3dntATPSerine/threonine-protein kinase toxin HipA/0.459
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
3lthUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.459
3o73O73Ribosyldihydronicotinamide dehydrogenase [quinone]/0.459
3pftFMNFlavin reductase/0.459
3sa27DRDihydrofolate reductase/0.459
3u8fFGMRibosome inactivating protein/0.459
3wnzADPAlanine--anticapsin ligase/0.459
4bvbOCZNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.459
4dlxGNPGTPase HRas/0.459
4dsbA8SAbscisic acid receptor PYL3/0.459
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.459
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
4gutFADLysine-specific histone demethylase 1B10.459
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.459
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.459
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.459
5c3aURMHisto-blood group ABO system transferase/0.459
1jcm137Tryptophan biosynthesis protein TrpCF4.1.1.480.458
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.458
2hruADPPhosphoribosylformylglycinamidine synthase subunit PurL/0.458
2rkuR78Serine/threonine-protein kinase PLK12.7.11.210.458
2wmrZYRSerine/threonine-protein kinase Chk12.7.11.10.458
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.458
3l04SN0N-acetylornithine carbamoyltransferase2.1.3.90.458
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.458
3to3ATPPetrobactin biosynthesis protein AsbB/0.458
4d9eLCSD-cysteine desulfhydrase/0.458
4f700STCyclin-dependent kinase 82.7.11.220.458
4jhz1KVBeta-glucuronidase3.2.1.310.458
5difGNPGTP-binding nuclear protein Ran/0.458
1og1TADT-cell ecto-ADP-ribosyltransferase 2/0.457
1x8b824Wee1-like protein kinase2.7.10.20.457
1yhoTRRDihydrofolate reductase1.5.1.30.457
2owb626Serine/threonine-protein kinase PLK12.7.11.210.457
2xvw9NRSerum albumin/0.457
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
3eigMTXDihydrofolate reductase1.5.1.30.457
3p79P79Mitogen-activated protein kinase 14/0.457
3q2mCKISpectinomycin phosphotransferase/0.457
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.457
3qfsNAPNADPH--cytochrome P450 reductase/0.457
3rl35GPMetallophosphoesterase MPPED23.10.457
4a4xJUPSerine/threonine-protein kinase Nek22.7.11.10.457
4dp3MMVBifunctional dihydrofolate reductase-thymidylate synthase/0.457
4fgj1PQRibosyldihydronicotinamide dehydrogenase [quinone]/0.457
2a9z26AAdenosine kinase2.7.1.200.456
2cjeDUNDUTPase/0.456
2e0nSAHPrecorrin-2 C20-methyltransferase/0.456
2ihtTPPN(2)-(2-carboxyethyl)arginine synthase/0.456
2opqHBQGag-Pol polyprotein2.7.7.490.456
2z1xPRFQueuine tRNA-ribosyltransferase2.4.2.290.456
3k4551PDihydrofolate reductase1.5.1.30.456
3nxoD2BDihydrofolate reductase1.5.1.30.456
3nytULPUDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.456
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.456
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.456
4dlzGNPGTPase HRas/0.456
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.456
4xq6FMNDihydroorotate dehydrogenase (quinone)/0.456
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.456
1bozPRDDihydrofolate reductase1.5.1.30.455
1synF89Thymidylate synthase/0.455
2c94TSF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.455
2h4k509Tyrosine-protein phosphatase non-receptor type 13.1.3.480.455
2itvANPEpidermal growth factor receptor2.7.10.10.455
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.455
2ov2GCPRas-related C3 botulinum toxin substrate 3/0.455
2rgxAP5Adenylate kinase/0.455
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.455
3be2RAJVascular endothelial growth factor receptor 22.7.10.10.455
3nbxADPATPase RavA3.6.30.455
3oimVZ5Carbonic anhydrase 24.2.1.10.455
3v0n4GWHisto-blood group ABO system transferase/0.455
3znrNU9Histone deacetylase 73.5.1.980.455
4b722FBBeta-secretase 13.4.23.460.455
4cryACOPanD regulatory factor/0.455
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.455
4lm4JPZcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.455
4nh82LCHeat shock protein HSP 90-alpha/0.455
5iubCLRAdenosine receptor A2a/0.455
1e94ANPATP-dependent protease ATPase subunit HslU/0.454
1g28FMNPHY3/0.454
1h83FADPolyamine oxidase1.5.3.140.454
1i5cADPChemotaxis protein CheA2.7.13.30.454
1kqgMGDFormate dehydrogenase, nitrate-inducible, major subunit1.1.5.60.454
1ludTRRDihydrofolate reductase1.5.1.30.454
1pxgPRFQueuine tRNA-ribosyltransferase2.4.2.290.454
1touB1VFatty acid-binding protein, adipocyte/0.454
1yw9A84Methionine aminopeptidase 2/0.454
2ag0TPPBenzaldehyde lyase/0.454
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
2pulACPMethylthioribose kinase2.7.1.1000.454
2vk8TPPPyruvate decarboxylase isozyme 1/0.454
2vr0HQOCytochrome c-type protein/0.454
3kqjUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.454
3nxrD2DDihydrofolate reductase1.5.1.30.454
3qfcNAPNADPH--cytochrome P450 reductase/0.454
3v0m5GWHisto-blood group ABO system transferase/0.454
3v4fGNPGTPase HRas/0.454
4k39SAMAnaerobic sulfatase-maturating enzyme1.8.980.454
4m10ICDProstaglandin G/H synthase 21.14.99.10.454
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.454
5bpfADPD-alanine--D-alanine ligase/0.454
1xpcAITEstrogen receptor/0.453
1zji2PG2-dehydro-3-deoxyphosphooctonate aldolase2.5.1.550.453
2aj8SC3Dipeptidyl peptidase 4/0.453
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.453
2c3dCOM2-oxopropyl-CoM reductase, carboxylating1.8.1.50.453
2ihuTP9N(2)-(2-carboxyethyl)arginine synthase/0.453
2itwITQEpidermal growth factor receptor2.7.10.10.453
2qe5617Polyprotein/0.453
2qhxFE1Pteridine reductase 11.5.1.330.453
2vczVC3Hematopoietic prostaglandin D synthase/0.453
3arpDEQChitinase A/0.453
3frfXCFDihydrofolate reductase1.5.1.30.453
3kr6UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.453
3qcmNXWReceptor-type tyrosine-protein phosphatase gamma3.1.3.480.453
3qgtCP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.453
3rs5GNPGTPase HRas/0.453
4fevPP1Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.453
4i6h1C8Serine/threonine-protein kinase PLK22.7.11.210.453
4ubfADPKinesin-like protein KIF2C/0.453
5h8tRTLRetinol-binding protein 1/0.453
5dhgDGVNociceptin receptor/0.453
1mdlRMNMandelate racemase/0.452
1zydATPeIF-2-alpha kinase GCN2/0.452
2bfpH4BPteridine reductase 11.5.1.330.452
2rgbGNPGTPase HRas/0.452
2wqoVGKSerine/threonine-protein kinase Nek22.7.11.10.452
2xkdT3MSerine/threonine-protein kinase Nek22.7.11.10.452
3a292T0Fructose-1,6-bisphosphatase 13.1.3.110.452
3d73NBBPheromone-binding protein ASP1/0.452
3fgoACPSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.452
3ix4TX1Transcriptional activator protein LasR/0.452
3mauPLRPutative sphingosine-1-phosphate lyase/0.452
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.452
3x065GPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1490.452
4cf7ADPAdenylate kinase/0.452
4gusFADLysine-specific histone demethylase 1B10.452
4hhdFMNPhototropin-12.7.11.10.452
4lb9EVPSerum albumin/0.452
1ftlDNQGlutamate receptor 2/0.451
1qoqIGPTryptophan synthase alpha chain/0.451
1qs2NADVip2Ac/0.451
1s6qTPBGag-Pol polyprotein2.7.7.490.451
1y6oMJIPhospholipase A2, major isoenzyme3.1.1.40.451
1zky689Estrogen receptor/0.451
2aqbTL63-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.451
2gzl2AA2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.451
2hxdDUPdCTP deaminase, dUMP-forming3.5.4.300.451
2ihvTPPN(2)-(2-carboxyethyl)arginine synthase/0.451
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.451
2qo9ANPEphrin type-A receptor 32.7.10.10.451
2v0uFMNNPH1-1/0.451
2vqjTFGHistone deacetylase 43.5.1.980.451
2wi72KLHeat shock protein HSP 90-alpha/0.451
2xnpWCXSerine/threonine-protein kinase Nek22.7.11.10.451
3aklADPSerine/threonine-protein kinase CtkA2.7.11.10.451
3b9lAZZSerum albumin/0.451
3dhbC6LN-acyl homoserine lactonase AiiA3.1.1.810.451
3gluLYS_VAL_METNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.451
3q7dNPXProstaglandin G/H synthase 21.14.99.10.451
3sbdGNPRas-related C3 botulinum toxin substrate 1/0.451
3srzUPGToxin A/0.451
3um5CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.451
4aovNAPIsocitrate dehydrogenase [NADP]/0.451
4c73TLH3-oxoacyl-ACP synthase/0.451
4f0fACPProbable serine/threonine-protein kinase roco42.7.11.10.451
4feu537Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.451
4go2TAPCytosolic 10-formyltetrahydrofolate dehydrogenase1.5.1.60.451
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.451
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.451
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.451
4oe4NADDelta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial1.2.1.880.451
4xivADPChemotaxis protein CheA2.7.13.30.451
1afsTES3-alpha-hydroxysteroid dehydrogenase1.1.1.500.450
1bmfADPATP synthase subunit alpha, mitochondrial/0.450
1bmfADPATP synthase subunit beta, mitochondrial3.6.3.140.450
1cq7PY5Aspartate aminotransferase2.6.1.10.450
1e7yNDPGlucose-6-phosphate 1-dehydrogenase/0.450
1o2eANNPhospholipase A23.1.1.40.450
1ove358Mitogen-activated protein kinase 14/0.450
1pnqNDPNAD(P) transhydrogenase subunit beta1.6.1.20.450
2bf7HBIPteridine reductase 11.5.1.330.450
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.450
2io6330Wee1-like protein kinase2.7.10.20.450
2isjFMN5,6-dimethylbenzimidazole synthase1.13.11.790.450
2rqfJH3Hemolymph juvenile hormone binding protein/0.450
2xkfBX1Serine/threonine-protein kinase Nek22.7.11.10.450
2xvv9DNSerum albumin/0.450
2zsiGA4Gibberellin receptor GID1A30.450
3bbpGTPRas-related protein Rab-6A/0.450
3bi6396Wee1-like protein kinase2.7.10.20.450
3cr0809Wee1-like protein kinase2.7.10.20.450
3fy9XCFDihydrofolate reductase1.5.1.30.450
3i8aN22Dihydrofolate reductase1.5.1.30.450
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
3k5eK5EKinesin-like protein KIF11/0.450
3ll9ADPIsopentenyl phosphate kinase/0.450
3oiwGNPGTPase HRas/0.450
3ozc4CTS-methyl-5'-thioadenosine phosphorylase/0.450
3phjDHKShikimate dehydrogenase (NADP(+))/0.450
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.450
4afeGGYSerine/threonine-protein kinase Nek22.7.11.10.450
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.450
4dxaGSPRas-related protein Rap-1b/0.450
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.450
4hu1V13Carbonic anhydrase 134.2.1.10.450
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.450
4o4eATPKinase/0.450
4zzjCNANAD-dependent protein deacetylase sirtuin-13.5.10.450
1cnfFADNitrate reductase [NADH]1.7.1.10.449
1cqsEQUSteroid Delta-isomerase5.3.3.10.449
1dlsMTXDihydrofolate reductase1.5.1.30.449
1hnvTBOGag-Pol polyprotein2.7.7.490.449
1mdrAPGMandelate racemase/0.449
1mp8ADPFocal adhesion kinase 12.7.10.20.449
1vruAAPGag-Pol polyprotein2.7.7.490.449
1x2hLPALipoate-protein ligase A6.3.1.200.449
1xowR18Androgen receptor/0.449
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.449
2cftPLPPyridoxal phosphate phosphatase/0.449
2fb35ADGTP 3',8-cyclase4.1.99.180.449
2j9gADPBiotin carboxylase6.3.4.140.449
3aiqHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic3.2.1.1820.449
3c72CX1Geranylgeranyl transferase type-2 subunit beta2.5.1.600.449
3njoPYVAbscisic acid receptor PYR1/0.449
4ap1NAPSteroid monooxygenase/0.449
4bwaN0BPyrrolysine--tRNA ligase/0.449
4deg0JJHepatocyte growth factor receptor2.7.10.10.449
4fflADPUncharacterized protein/0.449
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.449
4g8jTHMUridine phosphorylase/0.449
4i231C9Epidermal growth factor receptor2.7.10.10.449
4m4821BSodium-dependent dopamine transporter/0.449
4utkFNRXenobiotic reductase/0.449
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.449
5c8a5ADProbable transcriptional regulator/0.449
1l8qADPChromosomal replication initiator protein DnaA/0.448
1phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.448
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.448
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.448
2g44T3OEstrogen receptor/0.448
2hz0GINTyrosine-protein kinase ABL12.7.10.20.448
2ioaADPBifunctional glutathionylspermidine synthetase/amidase/0.448
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.448
2yg5FADPutrescine oxidase/0.448
3havATPAminoglycoside phosphotransferase/0.448
3junAJDPhenazine biosynthesis protein A/B/0.448
3x1zGNPRas-related protein Rap-1b/0.448
4b6r3DQ3-dehydroquinate dehydratase4.2.1.100.448
4ea2RWZDehydrosqualene synthase/0.448
4fgcPQ0NADPH-dependent 7-cyano-7-deazaguanine reductase1.7.1.130.448
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.448
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.448
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.448
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.448
4i4e1BQFocal adhesion kinase 12.7.10.20.448
4kouC04Uncharacterized protein/0.448
4mv4ACPBiotin carboxylase6.3.4.140.448
4q15HFGProline--tRNA ligase6.1.1.150.448
4qtnNNRNicotinamide riboside transporter PnuC/0.448
4uocNCNCinA-like protein/0.448
5je2SAHMethyl transferase/0.448
1ah3TOLAldose reductase1.1.1.210.447
1mdlSMNMandelate racemase/0.447
1n5sADLActVA 6 protein/0.447
1n71COAAac(6')-Ii protein/0.447
1ohkCOPDihydrofolate reductase1.5.1.30.447
1rdtL79Retinoic acid receptor RXR-alpha/0.447
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.447
2bfaCB3Pteridine reductase 11.5.1.330.447
2fa3ACOHydroxymethylglutaryl-CoA synthase/0.447
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.447
2rgeGNPGTPase HRas/0.447
2vagV25Dual specificity protein kinase CLK12.7.12.10.447
2x7jTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.447
2y0jAXCcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
3c36KAIGlutamate receptor ionotropic, kainate 1/0.447
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.447
3i5xANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.447
3nhyA7BRibosyldihydronicotinamide dehydrogenase [quinone]/0.447
3p0fBAUUridine phosphorylase 22.4.2.30.447
3pxkPXKFocal adhesion kinase 12.7.10.20.447
3rbaCODPhosphopantetheine adenylyltransferase/0.447
4aqlTXCGuanine deaminase3.5.4.30.447
4da6GA2Purine nucleoside phosphorylase DeoD-type2.4.2.10.447
4gu94GUFocal adhesion kinase 12.7.10.20.447
4i9z5BAcGMP-specific 3',5'-cyclic phosphodiesterase/0.447
4ig3T27Gag-Pol polyprotein2.7.7.490.447
4iv0SAMPhosphoethanolamine N-methyltransferase, putative/0.447
4j16NAPNAD(P) transhydrogenase subunit beta/0.447
4jva1ORcAMP-dependent protein kinase type II-beta regulatory subunit/0.447
4ph9IBPProstaglandin G/H synthase 21.14.99.10.447
4ypuSAMHistone-lysine N-methyltransferase ASH1L2.1.1.430.447
5aabVGHALK tyrosine kinase receptor2.7.10.10.447
5c3jUQ1Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial/0.447
5c3jUQ1Succinate dehydrogenase cytochrome b560/0.447
5c80URIUridine phosphorylase/0.447
5uviZMAAdenosine receptor A2a/0.447
1b9iPXG3-amino-5-hydroxybenzoate synthase4.2.1.1440.446
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.446
1e79ATPATP synthase subunit alpha, mitochondrial/0.446
1e79ATPATP synthase subunit beta, mitochondrial3.6.3.140.446
1i5aACPChemotaxis protein CheA2.7.13.30.446
1mvtDTMDihydrofolate reductase1.5.1.30.446
1pd8CO4Dihydrofolate reductase1.5.1.30.446
1tj0FADBifunctional protein PutA1.5.5.20.446
1trgCB3Thymidylate synthase/0.446
1tvcFDAMethane monooxygenase component C1.14.13.250.446
1u0wSTLChalcone synthase 22.3.1.740.446
1zy5ANPeIF-2-alpha kinase GCN2/0.446
2fjeFADAdenylylsulfate reductase, subunit A (AprA)/0.446
2ij7TPFMycocyclosin synthase1.14.21.90.446
2opsHBQGag-Pol polyprotein2.7.7.490.446
2w1eL0EAurora kinase A2.7.11.10.446
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.446
2z71PNVPenicillin acylase3.5.1.110.446
3g11P9C3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.446
3g5qFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.446
3nizADPCdc2-like CDK2/CDC28 like protein kinase/0.446
3nmvPYVAbscisic acid receptor PYL2/0.446
3tydXHPDihydropteroate synthase/0.446
4bdoKAIGlutamate receptor ionotropic, kainate 2/0.446
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.446
4e93GUITyrosine-protein kinase Fes/Fps2.7.10.20.446
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.446
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.446
4hw764MMacrophage colony-stimulating factor 1 receptor2.7.10.10.446
4ih71ERGenome polyprotein2.7.7.480.446
4iz02BIGenome polyprotein2.7.7.480.446
4lsjLSJGlucocorticoid receptor/0.446
4rr9A3SProbable threonine--tRNA ligase 26.1.1.30.446
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.446
1cd2FOLDihydrofolate reductase1.5.1.30.445
1giqNAIIota toxin component Ia/0.445
1kw6BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.445
1lb9DNQGlutamate receptor 2/0.445
1oynROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.445
1piwNAPNADP-dependent alcohol dehydrogenase 61.1.1.20.445
1w2dADPInositol-trisphosphate 3-kinase A2.7.1.1270.445
1yqj6NPMitogen-activated protein kinase 14/0.445
2fjdSFDAdenylylsulfate reductase, subunit A (AprA)/0.445
2j0vGDPRac-like GTP-binding protein ARAC7/0.445
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.445
2w3aTOPDihydrofolate reductase1.5.1.30.445
3ctj320Hepatocyte growth factor receptor2.7.10.10.445
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3flzFLZMitogen-activated protein kinase 14/0.445
3jq3ADPLombricine kinase/0.445
3l2kPXCEhpF/0.445
3lmhADPMyosin heavy chain kinase A2.7.11.70.445
3pg3DG7Mitogen-activated protein kinase 14/0.445
3pz3PZ3Geranylgeranyl transferase type-2 subunit beta2.5.1.600.445
3rps4B0Casein kinase II subunit alpha2.7.11.10.445
3sm0AEKQueuine tRNA-ribosyltransferase2.4.2.290.445
3vi5M4MHematopoietic prostaglandin D synthase/0.445
3zy6GFBGDP-fucose protein O-fucosyltransferase 12.4.1.2210.445
4gg90WWQueuine tRNA-ribosyltransferase2.4.2.290.445
4h6uACOAlpha-tubulin N-acetyltransferase 1/0.445
4h7zGUNQueuine tRNA-ribosyltransferase2.4.2.290.445
4jzr4JREgl nine homolog 1/0.445
4kxjP34Nucleoprotein/0.445
5fm7ADPRuvB-like helicase/0.445
5iqbGNPBifunctional AAC/APH2.3.10.445
4ug2NGIAdenosine receptor A2a/0.445
1e92HBIPteridine reductase 11.5.1.330.444
1lhuESTSex hormone-binding globulin/0.444
1q65BHBQueuine tRNA-ribosyltransferase2.4.2.290.444
2a2dANPN-acetylgalactosamine kinase2.7.1.1570.444
2b378PSEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.444
2clfF6FTryptophan synthase alpha chain/0.444
2e7zMGDAcetylene hydratase/0.444
2islFNR5,6-dimethylbenzimidazole synthase1.13.11.790.444
2r2nKYNKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.444
2uuoLK3UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.444
2x9vTMQPteridine reductase/0.444
2xnoED8Serine/threonine-protein kinase Nek22.7.11.10.444
2z7gEH9Adenosine deaminase3.5.4.40.444
2zshGA3Gibberellin receptor GID1A30.444
3c4wATPRhodopsin kinase/0.444
3itzP66Mitogen-activated protein kinase 14/0.444
3ix8TX3Transcriptional activator protein LasR/0.444
3jpuTY4Transcriptional activator protein LasR/0.444
3tl1JROPutative polyketide cyclase/0.444
4b6l9ZPSerine/threonine-protein kinase PLK32.7.11.210.444
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.444
4dm8REARetinoic acid receptor beta/0.444
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.444
4gu610NFocal adhesion kinase 12.7.10.20.444
4i41MIXSerine/threonine-protein kinase pim-12.7.11.10.444
4ixd1HVIntegrin alpha-L/0.444
4kak06UDihydrofolate reductase1.5.1.30.444
4m6l21VDihydrofolate reductase1.5.1.30.444
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.444
4xulGTPUncharacterized protein mg662/0.444
5b2zGNPGTPase HRas/0.444
5hbsRTLRetinol-binding protein 1/0.444
5ilwURIRibosome inactivating protein/0.444
1a8t061Metallo-beta-lactamase type 2/0.443
1fw0KAIGlutamate receptor 2/0.443
1i59ADPChemotaxis protein CheA2.7.13.30.443
1jf2CZHObelin/0.443
1knpFADL-aspartate oxidase1.4.3.160.443
1lhnAONSex hormone-binding globulin/0.443
1mraAPGMandelate racemase/0.443
1z6tADPApoptotic protease-activating factor 1/0.443
2bkzSBCCyclin-dependent kinase 22.7.11.220.443
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.443
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.443
2oj9BMIInsulin-like growth factor 1 receptor2.7.10.10.443
2pupADPMethylthioribose kinase2.7.1.1000.443
2q2zADPKinesin-like protein KIF11/0.443
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.443
2zjwREFCasein kinase II subunit alpha2.7.11.10.443
3bi5FADPolyamine oxidase FMS1/0.443
3dcv55ESerine/threonine-protein kinase pim-12.7.11.10.443
3eheNADUDP-glucose 4-epimerase (GalE-1)/0.443
3gep24HHypoxanthine-guanine phosphoribosyltransferase2.4.2.80.443
3imxB84Glucokinase2.7.1.20.443
3jq9AX1Pteridine reductase, putative/0.443
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
3ldfSAHUncharacterized protein/0.443
3nmpPYVAbscisic acid receptor PYL2/0.443
3ql3FOLDihydrofolate reductase1.5.1.30.443
4arbC57Acetylcholinesterase3.1.1.70.443
4c72TLG3-oxoacyl-ACP synthase/0.443
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.443
4euaCOASuccinyl-CoA:acetate CoA-transferase/0.443
4i13FOLDihydrofolate reductase1.5.1.30.443
4j97ACPFibroblast growth factor receptor 2/0.443
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.443
4l1xSTRAldo-keto reductase family 1 member C2/0.443
4l9y1VUL-malyl-CoA/beta-methylmalyl-CoA lyase4.1.3.240.443
4mitGTPRho-related protein racC/0.443
4o0mATPCircadian clock protein kinase KaiC2.7.11.10.443
5iqdGNPBifunctional AAC/APH2.3.10.443
3uzcT4EAdenosine receptor A2a/0.443
3reyXACAdenosine receptor A2a/0.443
1g9rUPFLgtC/0.442
1jtuLYBThymidylate synthase/0.442
1m78NDPDihydrofolate reductase1.5.1.30.442
1ne4RP1cAMP-dependent protein kinase type I-alpha regulatory subunit/0.442
1og4NAIT-cell ecto-ADP-ribosyltransferase 2/0.442
1oiuN76Cyclin-dependent kinase 22.7.11.220.442
1opbRETRetinol-binding protein 2/0.442
1qd1FONFormimidoyltransferase-cyclodeaminase2.1.2.50.442
1qk35GPHypoxanthine-guanine-xanthine phosphoribosyltransferase2.4.2.220.442
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.442
1rw8580TGF-beta receptor type-12.7.11.300.442
1wxjIPLTryptophan synthase alpha chain/0.442
1zisINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.442
2bxqIMNSerum albumin/0.442
2itxANPEpidermal growth factor receptor2.7.10.10.442
2ovhAS0Progesterone receptor/0.442
2x6o2TCTetracycline repressor protein class D/0.442
2yg3FADPutrescine oxidase/0.442
2ykbYKBHeat shock protein HSP 90-alpha/0.442
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.442
2zrfDTPProtein RecA/0.442
3c74ANUUridine phosphorylase2.4.2.30.442
3htjETEbrA repressor/0.442
3irn1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.442
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.442
3nuyJPZ3-phosphoinositide-dependent protein kinase 12.7.11.10.442
3nww3NWMitogen-activated protein kinase 14/0.442
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.442
3qvrFADGlucose oxidase1.1.3.40.442
3th5GNPRas-related C3 botulinum toxin substrate 1/0.442
3wfgWFGMineralocorticoid receptor/0.442
3zze6XPHepatocyte growth factor receptor2.7.10.10.442
4bb3KKAIsopenicillin N synthase1.21.3.10.442
4gd9BTNStreptavidin/0.442
4ix4ADPUncharacterized protein/0.442
4j6dTESCytochrome P450 monooxygenase/0.442
4k0bSAMS-adenosylmethionine synthase/0.442
4l8gGDPGTPase KRas/0.442
4oew5IOcGMP-specific 3',5'-cyclic phosphodiesterase/0.442
1ascNPLAspartate aminotransferase2.6.1.10.441
1dg7WRBDihydrofolate reductase1.5.1.30.441
1hpzAAPGag-Pol polyprotein2.7.7.490.441
1jtqLY3Thymidylate synthase/0.441
1lhwESMSex hormone-binding globulin/0.441
1ohoEQUSteroid Delta-isomerase5.3.3.10.441
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.441
1qjfACSIsopenicillin N synthase1.21.3.10.441
1rx02MCIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.441
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.441
1zrzBI1Protein kinase C iota type2.7.11.130.441
2a5kAZPReplicase polyprotein 1ab3.4.220.441
2bkuGTPGTP-binding nuclear protein Ran/0.441
2bxtC2DProthrombin3.4.21.50.441
2cd2FOLDihydrofolate reductase1.5.1.30.441
2ejzSAHDiphthine synthase/0.441
2idoTMPDNA polymerase III subunit epsilon2.7.7.70.441
2ipjFFAAldo-keto reductase family 1 member C2/0.441
2jdvL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
2uz1TPPBenzaldehyde lyase/0.441
2vcmM11Isopenicillin N synthase1.21.3.10.441
2wo7ASVIsopenicillin N synthase1.21.3.10.441
2xkeWI2Serine/threonine-protein kinase Nek22.7.11.10.441
2zevB71Geranylgeranyl pyrophosphate synthase/0.441
3a4pDFQHepatocyte growth factor receptor2.7.10.10.441
3axtSAMtRNA (guanine(26)-N(2)/guanine(27)-N(2))-dimethyltransferase/0.441
3c9tTPSThiamine-monophosphate kinase/0.441
3e6c3C4Cyclic nucleotide-binding protein/0.441
3evaSAHGenome polyprotein2.1.1.560.441
3ntaCOAFAD-dependent pyridine nucleotide-disulphide oxidoreductase/0.441
3nu03TUDihydrofolate reductase1.5.1.30.441
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.441
3qg2CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.441
3tleGSUMicrocin C7 self-immunity protein MccF/0.441
3tq8TOPDihydrofolate reductase/0.441
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.441
3uxe465Ribosyldihydronicotinamide dehydrogenase [quinone]/0.441
3vv8B02Beta-secretase 13.4.23.460.441
4b8lA0PAurora kinase B-A2.7.11.10.441
4bqyFNTEgl nine homolog 1/0.441
4fj1GEN17beta-hydroxysteroid dehydrogenase/0.441
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.441
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.441
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
4h0yNADIota toxin component Ia/0.441
4kko1REGag-Pol polyprotein2.7.7.490.441
4kp71UQ1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.441
4l17DNQGlutamate receptor 2/0.441
4p9dTMPDeoxycytidylate deaminase/0.441
4pb25UDNucleoside permease/0.441
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.441
4rr6A3SProbable threonine--tRNA ligase 26.1.1.30.441
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.441
4uakADPSerine/threonine-protein kinase MRCK beta2.7.11.10.441
5gcnCOAHAT A1/0.441
1cm8ANPMitogen-activated protein kinase 12/0.440
1db56INPhospholipase A2, membrane associated/0.440
1e1qADPATP synthase subunit beta, mitochondrial3.6.3.140.440
1exa394Retinoic acid receptor gamma/0.440
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.440
1olsTDP2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.440
1p0ePRFQueuine tRNA-ribosyltransferase2.4.2.290.440
1qv1CZHObelin/0.440
1r58AO5Methionine aminopeptidase 2/0.440
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.440
1u1gBBBUridine phosphorylase2.4.2.30.440
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.440
1z5cADPType 2 DNA topoisomerase 6 subunit B/0.440
2balPQAMitogen-activated protein kinase 14/0.440
2c5yMTWCyclin-dependent kinase 22.7.11.220.440
2c6tDT5Cyclin-dependent kinase 22.7.11.220.440
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.440
2fznFADBifunctional protein PutA1.5.5.20.440
2h00SAHU6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase/0.440
2h7jH7JCathepsin S3.4.22.270.440
2qmeGCPRas-related C3 botulinum toxin substrate 3/0.440
2vd0D27Hematopoietic prostaglandin D synthase/0.440
2w1gL0GAurora kinase A2.7.11.10.440
2wihP48Cyclin-dependent kinase 22.7.11.220.440
2xnmWGZSerine/threonine-protein kinase Nek22.7.11.10.440
2yy8SAMtRNA (cytidine(56)-2'-O)-methyltransferase/0.440
3a8wATPProtein kinase C iota type2.7.11.130.440
3bhtMFRCyclin-dependent kinase 22.7.11.220.440
3bloQEIQueuine tRNA-ribosyltransferase2.4.2.290.440
3c34KAIGlutamate receptor ionotropic, kainate 1/0.440
3ewkFADSensory box histidine kinase/response regulator/0.440
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
3hv3R49Mitogen-activated protein kinase 14/0.440
3l1cADPProtein claret segregational/0.440
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
3p2oNADBifunctional protein FolD/0.440
4at2ASDPossible succinate dehydrogenase/0.440
4awtFMNNADH:flavin oxidoreductase Sye1/0.440
4bb432WEphrin type-B receptor 42.7.10.10.440
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.440
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.440
4l091URTankyrase-22.4.2.300.440
4mv3ACPBiotin carboxylase6.3.4.140.440
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.440
4nmbFADBifunctional protein PutA/0.440
4uofDATNucleoside diphosphate kinase/0.440
4z87GDPInosine-5'-monophosphate dehydrogenase/0.440
4zfn5GPPurine phosphoribosyltransferase (GpT-2)/0.440
5bsrCOA4-coumarate--CoA ligase 26.2.1.120.440
5hwoHMGHydroxymethylglutaryl-CoA synthase/0.440