sc-PDB

List of CHEMBLId :

This value allows a number of roughly comparable measures of half-maximal response concentration/potency/affinity to be compared on a negative logarithmic scale (e.g., an IC50 measurement of 1nM would have a pChEMBL value of 9).

Uniprot Annotation

Name:	Phenylalanine-4-hydroxylase
ID:	PH4H_CHRVO
AC:	P30967
Organism:	Chromobacterium violaceum
Reign:	Bacteria
TaxID:	243365
EC Number:	1.14.16.1

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Chains:

Chain Name:	Percentage of Residues within binding site
A	100 %

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Ligand binding site composition:

B-Factor:	18.772
Number of residues:	26
Including
Standard Amino Acids:	25
Non Standard Amino Acids:	1
Water Molecules:	0
Cofactors:
Metals:	FE

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Cavity properties

Ligandability	Volume (Å3)
0.241	344.250

% Hydrophobic	% Polar
50.98	49.02
According to VolSite

HET Code:	HBI
Formula:	C9H13N5O3
Molecular weight:	239.231 g/mol
DrugBank ID:	DB04400
Buried Surface Area:	62.82 %
Polar Surface area:	132.33 Å2

Number of
H-Bond Acceptors:	7
H-Bond Donors:	5
Rings:	2
Aromatic rings:	0
Anionic atoms:	0
Cationic atoms:	0
Rule of Five Violation:	0
Rotatable Bonds:	2

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Mass center Coordinates

X	Y	Z
-16.1684	11.0303	26.7459

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