Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1ltzHBIPhenylalanine-4-hydroxylase1.14.16.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1ltzHBIPhenylalanine-4-hydroxylase1.14.16.11.000
1lrmHBIPhenylalanine-4-hydroxylase1.14.16.10.498
3c34KAIGlutamate receptor ionotropic, kainate 1/0.474
3c36KAIGlutamate receptor ionotropic, kainate 1/0.466
3c35KAIGlutamate receptor ionotropic, kainate 1/0.465
1qzzSAMAclacinomycin 10-hydroxylase RdmB4.1.10.459
3h03UBPGlutamate receptor 2/0.452
1j8uH4BPhenylalanine-4-hydroxylase1.14.16.10.450
2cdcNAPGlucose 1-dehydrogenase/0.450
4pahLNRPhenylalanine-4-hydroxylase1.14.16.10.450
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.448
1dmwHBIPhenylalanine-4-hydroxylase1.14.16.10.447
2d2gDZZPhosphotriesterase/0.447
2nnqT4BFatty acid-binding protein, adipocyte/0.446
2zs8ADPPantothenate kinase2.7.1.330.445
2rcwAAIPoly [ADP-ribose] polymerase 12.4.2.300.444
3hxeBD8Geranylgeranyl transferase type-2 subunit beta2.5.1.600.443
3upyFOMOxidoreductase, putative/0.443
4dldTZGGlutamate receptor ionotropic, kainate 1/0.443
5pahLDPPhenylalanine-4-hydroxylase1.14.16.10.443
1z5uCMPClass B acid phosphatase/0.442
2z7gEH9Adenosine deaminase3.5.4.40.441
4h8i11WGlutamate receptor ionotropic, kainate 2/0.441
3hv3R49Mitogen-activated protein kinase 14/0.440
3q2jCKIAminoglycoside 3'-phosphotransferase2.7.1.950.440
4l17DNQGlutamate receptor 2/0.440
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.440