sc-PDB

List of CHEMBLId :

This value allows a number of roughly comparable measures of half-maximal response concentration/potency/affinity to be compared on a negative logarithmic scale (e.g., an IC50 measurement of 1nM would have a pChEMBL value of 9).

Uniprot Annotation

Name:	DNA polymerase III subunit epsilon
ID:	DPO3E_ECOLI
AC:	P03007
Organism:	Escherichia coli
Reign:	Bacteria
TaxID:	83333
EC Number:	2.7.7.7

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Chains:

Chain Name:	Percentage of Residues within binding site
A	4 %
C	96 %

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Ligand binding site composition:

B-Factor:	24.285
Number of residues:	30
Including
Standard Amino Acids:	24
Non Standard Amino Acids:	2
Water Molecules:	4
Cofactors:
Metals:	MN MN

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Cavity properties

Ligandability	Volume (Å3)
0.523	556.875

% Hydrophobic	% Polar
45.45	54.55
According to VolSite

HET Code:	TMP
Formula:	C10H13N2O8P
Molecular weight:	320.193 g/mol
DrugBank ID:	-
Buried Surface Area:	53.89 %
Polar Surface area:	161.1 Å2

Number of
H-Bond Acceptors:	8
H-Bond Donors:	2
Rings:	2
Aromatic rings:	0
Anionic atoms:	2
Cationic atoms:	0
Rule of Five Violation:	0
Rotatable Bonds:	4

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Mass center Coordinates

X	Y	Z
19.2027	56.5053	8.85524

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