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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2rtqIMIStreptavidin

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2rtqIMIStreptavidin/1.000
2rtrIMIStreptavidin/0.810
2rtfBTNStreptavidin/0.695
3ry2BTNStreptavidin/0.693
2izgBTNStreptavidin/0.689
1lcwSHMStreptavidin/0.681
2y3fBTNStreptavidin/0.679
2izhBTNStreptavidin/0.674
4dneDTBStreptavidin/0.665
1srhMOBStreptavidin/0.664
4bx7B4FStreptavidin/0.664
1srfMTBStreptavidin/0.661
3wznBTNStreptavidin/0.657
1lczBH7Streptavidin/0.655
1srgMHBStreptavidin/0.647
2rtpIMIStreptavidin/0.646
2rtoIMIStreptavidin/0.645
1mk5BTNStreptavidin/0.644
1df8BTNStreptavidin/0.642
2izfBTNStreptavidin/0.641
2rtgBTNStreptavidin/0.640
1sriDMBStreptavidin/0.639
1srjNABStreptavidin/0.638
2fhnBNIAvidin-related protein 4/5/0.638
2rteBTNStreptavidin/0.636
4gdaBTNStreptavidin/0.636
2rtdBTNStreptavidin/0.635
3wyqBTNStreptavidin/0.633
1i9hBNIStreptavidin/0.629
2izlIMIStreptavidin/0.629
1rxhBNIStreptavidin/0.626
1swtBTNStreptavidin/0.626
1sreHABStreptavidin/0.625
1luqBTNStreptavidin/0.624
1stpBTNStreptavidin/0.618
1swpBTQStreptavidin/0.615
2rtnIMIStreptavidin/0.612
2iziBTNStreptavidin/0.610
2rtmIMIStreptavidin/0.608
2izjBTNStreptavidin/0.601
1sweBTNStreptavidin/0.597
1nqmBTNStreptavidin/0.595
1swnBTNStreptavidin/0.595
1swpBTNStreptavidin/0.589
1y52BTNAvidin-related protein 4/5/0.587
4bcsBTNAvidin-related protein 4/5/0.583
2c4iBTNAvidin/0.581
3rdqDTBStreptavidin/0.578
1mepBTNStreptavidin/0.577
2aviBTNAvidin/0.567
4z28BTNHoefavidin/0.564
1n9mBTNStreptavidin/0.561
1swrBTNStreptavidin/0.560
2fhlBNIAvidin-related protein 4/5/0.559
1n43BTNStreptavidin/0.558
1nc9IMIStreptavidin/0.558
1ndjBTNStreptavidin/0.556
2uywBTNAvd protein/0.556
1avdBTNAvidin/0.547
4yvbBTNStreptavidin/0.546
2rtiGLLStreptavidin/0.545
4gd9BTNStreptavidin/0.545
2zscBTNTamavidin2/0.544
3t2wBTNAvidin/streptavidin/0.535
4bj8BTNAvidin/0.533
3ew2BTNHypothetical conserved protein/0.528
2uz2BTNAvd protein/0.527
2izkGLLStreptavidin/0.520
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.519
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.517
4bb3KKAIsopenicillin N synthase1.21.3.10.515
2rtkGLLStreptavidin/0.512
3c3xNAPEugenol synthase 11.1.1.3180.510
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.509
2jgsBTNAvidin/0.509
3wypBSOStreptavidin/0.508
1nm6L86Prothrombin3.4.21.50.507
1swdBTNStreptavidin/0.507
3uk6ADPRuvB-like 23.6.4.120.502
4mryCEIObelin/0.501
3wtkTH4Acetylcholine-binding protein/0.499
2d32ANPGlutamate--cysteine ligase6.3.2.20.498
1nw6SFGModification methylase RsrI2.1.1.720.497
2bdyUNBProthrombin3.4.21.50.495
4a81DXCMajor pollen allergen Bet v 1-A/0.495
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.495
4dpy2P0Mevalonate diphosphate decarboxylase/0.494
4ggzBTNBll1558 protein/0.494
1fvpFMANon-fluorescent flavoprotein/0.493
2zfr46UProthrombin3.4.21.50.492
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.491
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.491
3pqbVGPPutative oxidoreductase/0.491
4q0kGA3Phytohormone-binding protein/0.491
1d9i00PProthrombin3.4.21.50.488
1pq944BOxysterols receptor LXR-beta/0.488
2zjwREFCasein kinase II subunit alpha2.7.11.10.488
5eccNAPDehydrofolate reductase type I/0.488
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.487
2fszOHTEstrogen receptor beta/0.486
1pqc444Oxysterols receptor LXR-beta/0.484
2yp0OVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.484
4a83DXCMajor pollen allergen Bet v 1-A/0.484
4c6zTLE3-oxoacyl-ACP synthase/0.484
4gyy12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.484
2bfqAR6[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.483
2tohHBITyrosine 3-monooxygenase1.14.16.20.483
4bquCLRJapanin/0.483
4ure1PSCyclohexanol dehydrogenase/0.483
1cjvFOKAdenylate cyclase type 2/0.482
1cjvFOKAdenylate cyclase type 5/0.482
1h36R88Squalene--hopene cyclase4.2.1.1290.482
1yc2NADNAD-dependent protein deacylase 2/0.482
1zdwFLVPrenyltransferase/0.482
2aqbTL63-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.482
2f4jVX6Tyrosine-protein kinase ABL12.7.10.20.482
3vhhVHHAvidin/0.482
4ax9N5NProthrombin3.4.21.50.482
1obnASVIsopenicillin N synthase1.21.3.10.481
1pd9CO4Dihydrofolate reductase1.5.1.30.481
1trgCB3Thymidylate synthase/0.481
3vgwNVZAvidin/0.481
1s3uTQDDihydrofolate reductase1.5.1.30.480
3atzFMNProstaglandin F2a synthase/0.480
3bw2FMNPutative 2-nitropropane dioxygenase/0.480
4twnB96Ephrin type-A receptor 32.7.10.10.480
1c4uIH1Prothrombin3.4.21.50.479
2cn0F25Prothrombin3.4.21.50.479
2w6mOA1Biotin carboxylase6.3.4.140.479
2xlsFADPutative flavin-containing monooxygenase/0.479
4l5b1UXDeoxycytidine kinase2.7.1.740.479
1dliUDXUDP-glucose 6-dehydrogenase/0.478
1m9nAMZBifunctional purine biosynthesis protein PURH2.1.2.30.478
1p8dCO1Oxysterols receptor LXR-beta/0.478
2rtlIMIStreptavidin/0.478
2zc922UProthrombin3.4.21.50.478
3d4bDZDNAD-dependent protein deacetylase/0.478
4psbGA3Cytokinin-specific binding protein/0.478
4rheFMNFlavin prenyltransferase UbiX/0.478
1ci7UMPThymidylate synthase2.1.1.450.477
1d4pBPPProthrombin3.4.21.50.477
1e7qNAPGDP-L-fucose synthase/0.477
2fjbSFDAdenylylsulfate reductase, subunit A (AprA)/0.477
3l0lHC3Nuclear receptor ROR-gamma/0.477
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.477
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.477
4orkGDPBifunctional AAC/APH2.3.10.477
1towCRZFatty acid-binding protein, adipocyte/0.476
2r2mI50Prothrombin3.4.21.50.476
2xveFADPutative flavin-containing monooxygenase/0.476
3c15FOKAdenylate cyclase type 2/0.476
3c15FOKAdenylate cyclase type 5/0.476
3d7zGK5Mitogen-activated protein kinase 14/0.476
3gwfFADCyclohexanone monooxygenase/0.476
3jpuTY4Transcriptional activator protein LasR/0.476
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.476
3qt62P0Mevalonate diphosphate decarboxylase/0.476
1d6w00RProthrombin3.4.21.50.475
1z71L17Prothrombin3.4.21.50.475
2a5c8DAAvidin/0.475
4aosFADSteroid monooxygenase/0.475
1lkeDOGBilin-binding protein/0.474
1mueCDDProthrombin3.4.21.50.474
1oc1ASVIsopenicillin N synthase1.21.3.10.474
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.474
2qvdBERBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.474
3d5qT30Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.474
1gj4132Prothrombin3.4.21.50.473
1nw5SAMModification methylase RsrI2.1.1.720.473
1qknRALEstrogen receptor beta/0.473
3biu10UProthrombin3.4.21.50.473
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.473
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.473
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.473
4uohADPNucleoside diphosphate kinase/0.473
4uyg73BBromodomain-containing protein 2/0.473
5iqdGNPBifunctional AAC/APH2.3.10.473
1axwMTXThymidylate synthase/0.472
1eq2ADQADP-L-glycero-D-manno-heptose-6-epimerase/0.472
2xlrFADPutative flavin-containing monooxygenase/0.472
2xvhFADPutative flavin-containing monooxygenase/0.472
3cr0809Wee1-like protein kinase2.7.10.20.472
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.472
3v49PK0Androgen receptor/0.472
4c73TLH3-oxoacyl-ACP synthase/0.472
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.472
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.472
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.471
2fzbTOLAldose reductase1.1.1.210.471
2oegUPGUDP-glucose pyrophosphorylase/0.471
2xszATPRuvB-like 23.6.4.120.471
3tm5SFGUncharacterized protein/0.471
4k9pTPPBenzoylformate decarboxylase4.1.1.70.471
4n3l2FNProthrombin3.4.21.50.471
4rvuNDPProbable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein)/0.471
3qakUKAAdenosine receptor A2a/0.471
1hb1OCVIsopenicillin N synthase1.21.3.10.470
1kt6RTLRetinol-binding protein 4/0.470
2hziJINTyrosine-protein kinase ABL12.7.10.20.470
2pa7TYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.470
2qw8NAPEugenol synthase 11.1.1.3180.470
2x9dITCTetracycline repressor protein class D/0.470
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.470
3v76FDAUncharacterized protein/0.470
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.470
4ap3FADSteroid monooxygenase/0.470
1i24UPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.469
1ot7CHCBile acid receptor/0.469
1s7gNADNAD-dependent protein deacylase 2/0.469
2aq7TL53-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.469
2xw19NVSerum albumin/0.469
2z3uCRRCytochrome P450/0.469
3qwc98PProthrombin3.4.21.50.469
4bfzZVZPantothenate kinase2.7.1.330.469
4qerSTLPhospholipase A2 VRV-PL-VIIIa/0.469
1kt7RTLRetinol-binding protein 4/0.468
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.468
1vzqSHYProthrombin3.4.21.50.468
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.468
3bhrTHGThymidylate synthase/0.468
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.468
3o6o94MHeat shock protein 83/0.468
3owyEQUSteroid Delta-isomerase5.3.3.10.468
3pn4BB2Peptide deformylase 1B, chloroplastic/mitochondrial3.5.1.880.468
3zkuHCVIsopenicillin N synthase1.21.3.10.468
3zkyWT4Isopenicillin N synthase1.21.3.10.468
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.468
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.468
4j6bPLOCytochrome P450 monooxygenase/0.468
4n3cUD1UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.468
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.468
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.467
2i0zFADNAD(FAD)-utilizing dehydrogenases/0.467
2rs1W84Genome polyprotein/0.467
3fhxPXLPyridoxal kinase2.7.1.350.467
3zeiAWHO-acetylserine sulfhydrylase/0.467
4dliIRGMitogen-activated protein kinase 14/0.467
4dymIYZActivin receptor type-12.7.11.300.467
4i4b1CV3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.467
4mo2FADUDP-galactopyranose mutase/0.467
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.466
2j9lATPH(+)/Cl(-) exchange transporter 5/0.466
2vcwZZAHematopoietic prostaglandin D synthase/0.466
3a25SAMtRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase/0.466
3aw9NADNAD-dependent epimerase/dehydratase/0.466
3h3sH15Collagen type IV alpha-3-binding protein/0.466
3q2jCKIAminoglycoside 3'-phosphotransferase2.7.1.950.466
3vweCOAAlpha-tubulin N-acetyltransferase 1/0.466
4avgSL6Polymerase acidic protein/0.466
4fam0SZAldo-keto reductase family 1 member C3/0.466
4u9yCOAAlpha-tubulin N-acetyltransferase 1/0.466
4x24TDI5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase/0.466
5fuwTHMThymidine kinase, putative/0.466
1d3dBZTProthrombin3.4.21.50.465
1diuBDMDihydrofolate reductase1.5.1.30.465
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.465
1jnrFADAdenylylsulfate reductase, subunit A (AprA)/0.465
1kt3RTLRetinol-binding protein 4/0.465
1rjkVDZVitamin D3 receptor/0.465
1xs7MMIBeta-secretase 13.4.23.460.465
1z7yAA5Cysteine synthase 12.5.1.470.465
2jb4A14Isopenicillin N synthase1.21.3.10.465
2w6qOA5Biotin carboxylase6.3.4.140.465
3elm24FCollagenase 33.4.240.465
3fznD7KBenzoylformate decarboxylase4.1.1.70.465
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.465
3qlsNDPDihydrofolate reductase1.5.1.30.465
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.465
4ez8DHFThymidylate synthase2.1.1.450.465
4mqt2CUMuscarinic acetylcholine receptor M2/0.465
1jnzFADAdenylylsulfate reductase, subunit A (AprA)/0.464
1nzq162Prothrombin3.4.21.50.464
1qjfACSIsopenicillin N synthase1.21.3.10.464
1upw444Oxysterols receptor LXR-beta/0.464
1ypeUIPProthrombin3.4.21.50.464
2fjaFADAdenylylsulfate reductase, subunit A (AprA)/0.464
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.464
2nsd4PIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.464
2wmdZZ0NmrA-like family domain-containing protein 1/0.464
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.464
3i5xANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.464
4pnmNU1Tankyrase-22.4.2.300.464
1dnaCB3Thymidylate synthase/0.463
1m78NDPDihydrofolate reductase1.5.1.30.463
1nc1MTH5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase3.2.2.90.463
1z6tADPApoptotic protease-activating factor 1/0.463
2az3CDPNucleoside diphosphate kinase/0.463
2bxtC2DProthrombin3.4.21.50.463
2p5yNADUDP-glucose 4-epimerase/0.463
2uupLK4UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.463
2x7hPFNProstaglandin reductase 310.463
3ansS38Bifunctional epoxide hydrolase 23.3.2.100.463
3arvSAUChitinase A/0.463
3kozZ97D-ornithine 4,5-aminomutase subunit beta/0.463
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.463
3uyk0CXProbable NDP-rhamnosyltransferase/0.463
4a2aATPCell division protein FtsA/0.463
4knzCB3Thymidylate synthase/0.463
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.463
4z24FADPutative GMC-type oxidoreductase R13510.463
1cdeGARPhosphoribosylglycinamide formyltransferase/0.462
1ikgREXD-alanyl-D-alanine carboxypeptidase3.4.16.40.462
1kceCB3Thymidylate synthase/0.462
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.462
1nbiSAMGlycine N-methyltransferase2.1.1.200.462
1ta6177Prothrombin3.4.21.50.462
1tsxUMPThymidylate synthase/0.462
1uhjCZBAequorin-2/0.462
2cf9348Prothrombin3.4.21.50.462
2ftoCB3Thymidylate synthase/0.462
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.462
2zhw12UProthrombin3.4.21.50.462
3bi6396Wee1-like protein kinase2.7.10.20.462
3eeiMTM5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase/0.462
3q44D50M1 family aminopeptidase3.4.110.462
3qlrNDPDihydrofolate reductase1.5.1.30.462
3rl45GPMetallophosphoesterase MPPED23.10.462
4ys22BAUncharacterized protein/0.462
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.462
1efvFADElectron transfer flavoprotein subunit alpha, mitochondrial/0.461
1iiuRTLRetinol-binding protein 4/0.461
1j9zFADNADPH--cytochrome P450 reductase/0.461
1kw8BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.461
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.461
1ly4COQDihydrofolate reductase1.5.1.30.461
1wsvTHHAminomethyltransferase, mitochondrial/0.461
2bn4FADNADPH--cytochrome P450 reductase/0.461
2bunFADAppA protein/0.461
2hamC33Vitamin D3 receptor/0.461
2o4jVD4Vitamin D3 receptor/0.461
2ydoADNAdenosine receptor A2a/0.461
2yk2YJXHeat shock protein HSP 90-alpha/0.461
3ehjACPSensor histidine kinase DesK2.7.13.30.461
3owuEQUSteroid Delta-isomerase5.3.3.10.461
3q71AR6Poly [ADP-ribose] polymerase 142.4.2.300.461
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.461
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.461
4j6dTESCytochrome P450 monooxygenase/0.461
1cjkFOKAdenylate cyclase type 2/0.460
1cjkFOKAdenylate cyclase type 5/0.460
1cjtFOKAdenylate cyclase type 2/0.460
1cjtFOKAdenylate cyclase type 5/0.460
1gky5GPGuanylate kinase2.7.4.80.460
1ie9VDXVitamin D3 receptor/0.460
1o2g696Prothrombin3.4.21.50.460
1tj2FADBifunctional protein PutA1.5.5.20.460
2c29NAPDihydroflavonol 4-reductase/0.460
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.460
2v57PRLTetR family transcriptional regulator/0.460
2w6oOA3Biotin carboxylase6.3.4.140.460
2zhf49UProthrombin3.4.21.50.460
3f63GTXGlutathione transferase GST1-4/0.460
3g5qFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.460
3lz6A0DCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.460
3p62FMNPentaerythritol tetranitrate reductase/0.460
3rbqGLY_ALA_GLY_ALA_DAOProtein unc-119 homolog A/0.460
3rupADPBiotin carboxylase6.3.4.140.460
3v4aPK1Androgen receptor/0.460
1efaNPFLactose operon repressor/0.459
1f4gTP4Thymidylate synthase/0.459
1piwNAPNADP-dependent alcohol dehydrogenase 61.1.1.20.459
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.459
2fjdSFDAdenylylsulfate reductase, subunit A (AprA)/0.459
2hb8MVDVitamin D3 receptor/0.459
2iyfERYOleandomycin glycosyltransferase2.4.10.459
2x7jTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.459
2y6fM9FIsopenicillin N synthase1.21.3.10.459
2ym1FADPhenylacetone monooxygenase1.14.13.920.459
3oewNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.459
3pe13NGCasein kinase II subunit alpha2.7.11.10.459
4g6hNAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.459
4hkfACOAlpha-tubulin N-acetyltransferase 1/0.459
4wuoNAD3-isopropylmalate dehydrogenase1.1.1.850.459
5iqbGNPBifunctional AAC/APH2.3.10.459
3emlZMAAdenosine receptor A2a/0.459
1afsTES3-alpha-hydroxysteroid dehydrogenase1.1.1.500.458
1disBDMDihydrofolate reductase1.5.1.30.458
1m67BOAGlycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal1.1.1.80.458
1m79MQ1Dihydrofolate reductase1.5.1.30.458
1mabADPATP synthase subunit beta, mitochondrial3.6.3.140.458
1nceCB3Thymidylate synthase/0.458
1p33MTXPteridine reductase 11.5.1.330.458
1pw6FRBInterleukin-2/0.458
1r2jFADFkbI/0.458
1tj0FADBifunctional protein PutA1.5.5.20.458
1vruAAPGag-Pol polyprotein2.7.7.490.458
1yplRA8Prothrombin3.4.21.50.458
2npfMOUElongation factor 2/0.458
2pl0STITyrosine-protein kinase Lck2.7.10.20.458
2qx7NAPEugenol synthase 11.1.1.3180.458
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1840.458
3a1l2CCCytochrome P450/0.458
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
3fr5I4AFatty acid-binding protein, adipocyte/0.458
3hv3R49Mitogen-activated protein kinase 14/0.458
3maaFKPAdenylate cyclase type 2/0.458
3maaFKPAdenylate cyclase type 5/0.458
3ol5SAWCamphor 5-monooxygenase1.14.15.10.458
3t8vBTJM1 family aminopeptidase3.4.110.458
3w8wFADPutative FAD-dependent oxygenase EncM/0.458
4at3LTIBDNF/NT-3 growth factors receptor2.7.10.10.458
4bakM67Prothrombin3.4.21.50.458
4fhbFOLDihydrofolate reductase1.5.1.30.458
1eioGCHGastrotropin/0.457
1g0nNDPTetrahydroxynaphthalene reductase1.1.1.2520.457
1qiqACCIsopenicillin N synthase1.21.3.10.457
1suiFRECaffeoyl-CoA O-methyltransferase2.1.1.1040.457
1ycgFMNNitric oxide reductase10.457
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.457
2kceD16Thymidylate synthase/0.457
2vmyFFOSerine hydroxymethyltransferase/0.457
2yphQQY2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.457
2zff53UProthrombin3.4.21.50.457
2zi224UProthrombin3.4.21.50.457
2znq401Peroxisome proliferator-activated receptor delta/0.457
3biz61EWee1-like protein kinase2.7.10.20.457
3g1oRF1HTH-type transcriptional regulator EthR/0.457
3gkjHC3Niemann-Pick C1 protein/0.457
3pz23PZGeranylgeranyl transferase type-2 subunit beta2.5.1.600.457
3uwlFOZThymidylate synthase/0.457
4bahMELProthrombin3.4.21.50.457
4dz5NAPAldo-keto reductase family 1 member C3/0.457
4gs4ACOAlpha-tubulin N-acetyltransferase 1/0.457
4rtmSAMDNA adenine methylase2.1.1.720.457
4rupH97Vitamin D3 receptor A/0.457
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.457
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.457
5hs1VORLanosterol 14-alpha demethylase/0.457
1bq1CB3Thymidylate synthase/0.456
1db1VDXVitamin D3 receptor/0.456
1xoqROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.456
1yqzCOACoenzyme A disulfide reductase/0.456
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.456
2gvdFKPAdenylate cyclase type 2/0.456
2gvdFKPAdenylate cyclase type 5/0.456
2r8pT6FTransketolase 1/0.456
2tscCB3Thymidylate synthase/0.456
2v3oI26Prothrombin3.4.21.50.456
2v5aLZLBiotin carboxylase6.3.4.140.456
2zhe13UProthrombin3.4.21.50.456
3bw4FMNPutative 2-nitropropane dioxygenase/0.456
3gdpFAD(R)-mandelonitrile lyase 24.1.2.100.456
3i1y33NBifunctional epoxide hydrolase 23.3.2.100.456
4avlTMPPolymerase acidic protein/0.456
4c2z646Glycylpeptide N-tetradecanoyltransferase 1/0.456
4ge1TSSBiogenic amine-binding protein/0.456
4hmbPZZPhospholipase A2 VRV-PL-VIIIa/0.456
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.456
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.456
4rtsSAMDNA adenine methylase2.1.1.720.456
4wdfA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.456
4xg1LLPDiaminopimelate decarboxylase/0.456
1dr4HBIDihydrofolate reductase1.5.1.30.455
1equEQIEstradiol 17-beta-dehydrogenase 11.1.1.620.455
1gj5130Prothrombin3.4.21.50.455
1wklATPNucleoside diphosphate kinase/0.455
1y0s331Peroxisome proliferator-activated receptor delta/0.455
2acwUPGGlycosyltransferase/0.455
2idkC2FGlycine N-methyltransferase2.1.1.200.455
3d84NDPDihydrofolate reductase1.5.1.30.455
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.455
3fhxPLPPyridoxal kinase2.7.1.350.455
3flwFLWMitogen-activated protein kinase 14/0.455
3qly55VUncharacterized protein/0.455
3utu1TSProthrombin3.4.21.50.455
3vtdTKDVitamin D3 receptor/0.455
4ap1FADSteroid monooxygenase/0.455
4v0s2HN3-dehydroquinate dehydratase4.2.1.100.455
7catNDPCatalase1.11.1.60.455
1bk0ACVIsopenicillin N synthase1.21.3.10.454
1booSAHModification methylase PvuII2.1.1.1130.454
1culFOKAdenylate cyclase type 2/0.454
1culFOKAdenylate cyclase type 5/0.454
1d3hA26Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.454
1dr3HBIDihydrofolate reductase1.5.1.30.454
1eg2MTAModification methylase RsrI2.1.1.720.454
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.454
1ia2TQ4Dihydrofolate reductase1.5.1.30.454
1p91SAM23S rRNA (guanine(745)-N(1))-methyltransferase/0.454
1r8qAFBCytohesin-2/0.454
1r8qAFBADP-ribosylation factor 1/0.454
1w7h3IPMitogen-activated protein kinase 14/0.454
1ychFMNNitric oxide reductase10.454
1zq5E04Aldo-keto reductase family 1 member C3/0.454
2fa3ACOHydroxymethylglutaryl-CoA synthase/0.454
2ofv242Tyrosine-protein kinase Lck2.7.10.20.454
2ozrGG1Collagenase 33.4.240.454
2wo7ASVIsopenicillin N synthase1.21.3.10.454
2zgx29UProthrombin3.4.21.50.454
3aosJH2Hemolymph juvenile hormone binding protein/0.454
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.454
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.454
3nmpPYVAbscisic acid receptor PYL2/0.454
3oct1N1Tyrosine-protein kinase BTK2.7.10.20.454
3pm9FADPutative oxidoreductase/0.454
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.454
3r0tFU9Casein kinase II subunit alpha2.7.11.10.454
3v0o4GWHisto-blood group ABO system transferase/0.454
4b5nFMNNAD(P)H:flavin oxidoreductase Sye4/0.454
4blcNDPCatalase1.11.1.60.454
4e5h0N8Polymerase acidic protein/0.454
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.454
4h8004TAldehyde dehydrogenase, dimeric NADP-preferring/0.454
4h9506UDihydrofolate reductase1.5.1.30.454
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.454
4xivADPChemotaxis protein CheA2.7.13.30.454
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
5fsxADPUncharacterized protein/0.454
5hwpCOAHydroxymethylglutaryl-CoA synthase/0.454
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.454
1ae8AZLProthrombin3.4.21.50.453
1db48INPhospholipase A2, membrane associated/0.453
1e26GPBDihydrofolate reductase1.5.1.30.453
1rkgVD1Vitamin D3 receptor/0.453
1zuaTOLAldo-keto reductase family 1 member B101.1.10.453
2b03TUDPhospholipase A2, major isoenzyme3.1.1.40.453
2j14GNIPeroxisome proliferator-activated receptor delta/0.453
2rr1W8RGenome polyprotein/0.453
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.453
3e92G6AMitogen-activated protein kinase 14/0.453
3l7dDK5Glycogen phosphorylase, muscle form2.4.1.10.453
3m0oFADMonomeric sarcosine oxidase1.5.3.10.453
3nytULPUDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.453
3qizQI2Botulinum neurotoxin type A3.4.24.690.453
3v97SAHRibosomal RNA large subunit methyltransferase K/L2.1.1.1730.453
3w2eNADNADH-cytochrome b5 reductase 31.6.2.20.453
4b63NAPL-ornithine N(5)-monooxygenase/0.453
4bb432WEphrin type-B receptor 42.7.10.10.453
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.453
4c72TLG3-oxoacyl-ACP synthase/0.453
4epxGDPGTPase KRas/0.453
1c4yIH3Prothrombin3.4.21.50.452
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.452
1lnmDTXBilin-binding protein/0.452
1qf5RPLAdenylosuccinate synthetase/0.452
1tysDHFThymidylate synthase/0.452
1uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.452
1x1cSAHC-20 methyltransferase/0.452
2aa71CAMineralocorticoid receptor/0.452
2aaxPDNMineralocorticoid receptor/0.452
3bk2U5PRibonuclease J/0.452
3dejRXCCaspase-33.4.22.560.452
3invNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.452
3jynNDPQuinone oxidoreductase/0.452
3sp9IL2Peroxisome proliferator-activated receptor delta/0.452
3vt45YIVitamin D3 receptor/0.452
4d9eLCSD-cysteine desulfhydrase/0.452
4eh8IRGMitogen-activated protein kinase 14/0.452
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
4i8vBHFCytochrome P450 1A11.14.14.10.452
4kf1HT5Aryldialkylphosphatase3.1.8.10.452
4lnbED5CaaX farnesyltransferase beta subunit Ram1/0.452
4n6hEJ4Delta-type opioid receptor/0.452
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.452
4okx198Androgen receptor/0.452
4rujVDXVitamin D3 receptor A/0.452
4xd1T3QQdtf/0.452
5esdTDP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.452
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.451
1rszDIHPurine nucleoside phosphorylase2.4.2.10.451
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.451
2bjsACVIsopenicillin N synthase1.21.3.10.451
2cd2FOLDihydrofolate reductase1.5.1.30.451
2fonFADAcyl-coenzyme A oxidase/0.451
2fziDH3Dihydrofolate reductase1.5.1.30.451
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.451
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.451
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.451
2r0pK2CPutative FAD-monooxygenase/0.451
2vqbFADPutative flavin-containing monooxygenase/0.451
2xlpFADPutative flavin-containing monooxygenase/0.451
2xvfFADPutative flavin-containing monooxygenase/0.451
2y6o1N1Ephrin type-A receptor 42.7.10.10.451
2ylpTESAndrogen receptor/0.451
2ylwFADPhenylacetone monooxygenase1.14.13.920.451
2z2w770Wee1-like protein kinase2.7.10.20.451
3bloQEIQueuine tRNA-ribosyltransferase2.4.2.290.451
3iej599Cathepsin S3.4.22.270.451
3juqAKDPhenazine biosynthesis protein A/B/0.451
3mg3ECHOrange carotenoid-binding protein/0.451
3nguADPNucleoside diphosphate kinase/0.451
3p9kCIYCaffeic acid O-methyltransferase/0.451
4ayy9MXProthrombin3.4.21.50.451
4d86ADPPoly [ADP-ribose] polymerase 142.4.2.300.451
4g1z0VPVitamin D3 receptor A/0.451
4h6zACOAlpha-tubulin N-acetyltransferase 1/0.451
4i0t1B6Tyrosine-protein kinase SYK2.7.10.20.451
4ia3BIVVitamin D3 receptor A/0.451
4nt3ZAWLactoperoxidase1.11.1.70.451
4uyf73BBromodomain-containing protein 2/0.451
4z3dNDPCarbonyl reductase [NADPH] 11.1.1.1840.451
5fdg0N8Polymerase acidic protein/0.451
4s0vSUVOrexin receptor type 2/0.451
1dcyI3NPhospholipase A2, membrane associated/0.450
1e92HBIPteridine reductase 11.5.1.330.450
1gc5ADPADP-dependent glucokinase2.7.1.1470.450
1hb3SCVIsopenicillin N synthase1.21.3.10.450
1kqoDNDNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.450
1me7MOAInosine-5'-monophosphate dehydrogenase/0.450
1mu6CDAProthrombin3.4.21.50.450
1s7nCOAAcetyl transferase/0.450
1txiTX5Vitamin D3 receptor/0.450
1uydPU8Heat shock protein HSP 90-alpha/0.450
1vf2GTXGlutathione S-transferase 32.5.1.180.450
1ypkCCRProthrombin3.4.21.50.450
2b1z17MEstrogen receptor/0.450
2c3p1TPPyruvate synthase/0.450
2hasC3OVitamin D3 receptor/0.450
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.450
2v2qNVG4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.450
2xvu9DNSerum albumin/0.450
3gmd2M3Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.450
3mb601ICasein kinase II subunit alpha2.7.11.10.450
3owaFADAcyl-CoA dehydrogenase/0.450
3p9tTCLRepressor/0.450
3q9oNADCholix toxin2.4.2.360.450
3rimTPPTransketolase2.2.1.10.450
3v2uATPProtein GAL3/0.450
3vfqAR6Poly [ADP-ribose] polymerase 142.4.2.300.450
3wthIM4Acetylcholine-binding protein/0.450
3zc3FADFerredoxin--NADP reductase1.18.1.20.450
4cmfPXGUncharacterized protein/0.450
4emdC5P4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.450
4h6rFDAProline dehydrogenase/0.450
4isk1JYThymidylate synthase/0.450
4kp71UQ1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.450
4m9aFDAAcyl-CoA dehydrogenase/0.450
4n8iCOAPutative 4-hydroxybutyrate coenzyme A transferase/0.450
4u07ATPAdenosine monophosphate-protein transferase FICD2.7.7.n10.450
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.450
5stdUNNScytalone dehydratase4.2.1.940.450
5d6lCAUBeta-2 adrenergic receptor/0.450
1amoFADNADPH--cytochrome P450 reductase/0.449
1b9iPXG3-amino-5-hydroxybenzoate synthase4.2.1.1440.449
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.449
1dmyAZMCarbonic anhydrase 5A, mitochondrial4.2.1.10.449
1fmjRTLRetinol dehydratase/0.449
1kphSAHCyclopropane mycolic acid synthase 12.1.1.790.449
1kquBR4Phospholipase A2, membrane associated/0.449
1lwxAZDNucleoside diphosphate kinase, cytosolic2.7.4.60.449
1opbRETRetinol-binding protein 2/0.449
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.449
1zdfUPGGlycogenin-12.4.1.1860.449
1zgi382Prothrombin3.4.21.50.449
2d29FADAcyl-CoA dehydrogenase/0.449
2fzhDH1Dihydrofolate reductase1.5.1.30.449
2hq9FADMll6688 protein/0.449
2jj2ANPATP synthase subunit beta, mitochondrial3.6.3.140.449
2pksG44Prothrombin3.4.21.50.449
2uuk897Prothrombin3.4.21.50.449
2vcmM11Isopenicillin N synthase1.21.3.10.449
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.449
2xejOKDGlutamate carboxypeptidase 23.4.17.210.449
2zrvFNRIsopentenyl-diphosphate delta-isomerase/0.449
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.449
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
3uovFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.449
3vf60H6Glucokinase2.7.1.20.449
4aoxFADSteroid monooxygenase/0.449
4b45GSPTubulin-like protein CetZ2/0.449
4b4vL34Bifunctional protein FolD/0.449
4bj9UHBTankyrase-22.4.2.300.449
4dc0NDPPutative ketoacyl reductase1.3.10.449
4hw219HInduced myeloid leukemia cell differentiation protein Mcl-1/0.449
4hy6FJ1Heat shock protein HSP 90-alpha/0.449
4jq3ZOMAldo-keto reductase family 1 member C2/0.449
4k4eK4ETankyrase-12.4.2.300.449
4qknJMSAlpha-ketoglutarate-dependent dioxygenase FTO/0.449
5a2yUTPMitochondrial poly(A) polymerase/0.449
1dljUGAUDP-glucose 6-dehydrogenase/0.448
1gheACOAcetyltransferase2.3.10.448
1mrqSTRAldo-keto reductase family 1 member C1/0.448
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.448
1yimCM4Estrogen receptor/0.448
2gdeSN3Prothrombin3.4.21.50.448
2pg0FADAcyl-CoA dehydrogenase/0.448
2qa2FADPolyketide oxygenase CabE/0.448
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.448
2yloTESAndrogen receptor/0.448
2yy8SAMtRNA (cytidine(56)-2'-O)-methyltransferase/0.448
2zfq45UProthrombin3.4.21.50.448
3cgyRDCVirulence sensor histidine kinase PhoQ2.7.13.30.448
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
3ey4352Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.448
3f3y4OABile salt sulfotransferase2.8.2.140.448
3jqpA2PFerredoxin--NADP reductase, apicoplast/0.448
3mb714ICasein kinase II subunit alpha2.7.11.10.448
3mdmFJZCholesterol 24-hydroxylase/0.448
3oibFDAPutative acyl-CoA dehydrogenase/0.448
3p74FMNPentaerythritol tetranitrate reductase/0.448
3uleC69Actin-related protein 3/0.448
4a6eASEAcetylserotonin O-methyltransferase2.1.1.40.448
4azwATPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.448
4bfvZVVPantothenate kinase2.7.1.330.448
4c717RD3-oxoacyl-ACP synthase/0.448
4gdcNDPUDP-galactopyranose mutase/0.448
4gevCB3Thymidylate synthase/0.448
4h8i11WGlutamate receptor ionotropic, kainate 2/0.448
4o9cCOAAcetyl-CoA acetyltransferase2.3.1.90.448
4olfHFGProline--tRNA ligase6.1.1.150.448
4z26FADPutative GMC-type oxidoreductase R13510.448
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.448
5eghPCEctonucleotide pyrophosphatase/phosphodiesterase family member 6/0.448
1bsvNDPGDP-L-fucose synthase/0.447
1d3pBT3Prothrombin3.4.21.50.447
1ejbINJ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.447
1ezfIN0Squalene synthase2.5.1.210.447
1ia1NDPDihydrofolate reductase1.5.1.30.447
1krrACOGalactoside O-acetyltransferase2.3.1.180.447
1lhvNOGSex hormone-binding globulin/0.447
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.447
1vgrCOAFormyl-CoA:oxalate CoA-transferase/0.447
1xu7CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.447
1zx1CB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.447
2a2dANPN-acetylgalactosamine kinase2.7.1.1570.447
2a94AP0L-lactate dehydrogenase1.1.1.270.447
2a9y26AAdenosine kinase2.7.1.200.447
2harOCCVitamin D3 receptor/0.447
2jlcTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.447
2rc6NAPFerredoxin--NADP reductase/0.447
2rqfJH3Hemolymph juvenile hormone binding protein/0.447
2x6tNAPADP-L-glycero-D-manno-heptose-6-epimerase/0.447
2xtbKRMAdenosine kinase, putative/0.447
2zpaADPtRNA(Met) cytidine acetyltransferase TmcA/0.447
3angDCCTranscriptional repressor, TetR family/0.447
3biy01KHistone acetyltransferase p300/0.447
3crzFADFerredoxin--NADP+ reductase/0.447
3h1jSMACytochrome b/0.447
3o4rNAPDehydrogenase/reductase SDR family member 41.1.1.1840.447
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.447
3ufgATPGlycine--tRNA ligase alpha subunit/0.447
4a4vYFDPeroxisome proliferator-activated receptor gamma/0.447
4bc7FADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.447
4bfsZVSPantothenate kinase2.7.1.330.447
4bvhOCZNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.447
4g8bHL6Alpha/beta hydrolase fold protein/0.447
4kw51W6Decaprenylphosphoryl-beta-D-ribose oxidase/0.447
1blzACVIsopenicillin N synthase1.21.3.10.446
1cd2FOLDihydrofolate reductase1.5.1.30.446
1f9aATPNicotinamide-nucleotide adenylyltransferase/0.446
1fxsNAPGDP-L-fucose synthase/0.446
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.446
1kw6BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.446
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.446
1tj1FADBifunctional protein PutA1.5.5.20.446
1w7iADPUnconventional myosin-Va/0.446
1wmaAB3Carbonyl reductase [NADPH] 11.1.1.1840.446
2bvs2CEProthrombin3.4.21.50.446
2ekpNAD2-deoxy-D-gluconate 3-dehydrogenase/0.446
2gzl2AA2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.446
2nyaMGDPeriplasmic nitrate reductase1.7.99.40.446
2oc4IMHPurine nucleoside phosphorylase2.4.2.10.446
2pakTYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.446
2vbdV10Isopenicillin N synthase1.21.3.10.446
2vo4GTB2,4-D inducible glutathione S-transferase/0.446
2wotZZGTGF-beta receptor type-12.7.11.300.446
2zg050UProthrombin3.4.21.50.446
2zva1N1Tyrosine-protein kinase Lyn2.7.10.20.446
3c1kT15Prothrombin3.4.21.50.446
3c35KAIGlutamate receptor ionotropic, kainate 1/0.446
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.446
3freTOPDihydrofolate reductase1.5.1.30.446
3gncQQQGlutaryl-CoA dehydrogenase/0.446
3gyf51PDihydrofolate reductase1.5.1.30.446
3iktNADRedox-sensing transcriptional repressor Rex/0.446
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3keqNADRedox-sensing transcriptional repressor Rex/0.446
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.446
3kpzZNEVitamin D3 receptor/0.446
3pe2E1BCasein kinase II subunit alpha2.7.11.10.446
3up3XCAaceDAF-12/0.446
3vri1KXHLA class I histocompatibility antigen, B-57 alpha chain/0.446
3vrtYS2Vitamin D3 receptor/0.446
4ckrDI1Epithelial discoidin domain-containing receptor 12.7.10.10.446
4ead0NPThymidine phosphorylase2.4.2.40.446
4j3lAJ5Tankyrase-22.4.2.300.446
4l8u9AZSerum albumin/0.446
4pkwGM6Lethal factor3.4.24.830.446
4pztSOPHistone acetyltransferase p300/0.446
4tjy3GNTankyrase-22.4.2.300.446
4wkbTDI5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase/0.446
4ww4ADPRuvB-like helicase/0.446
4yddMD1DMSO reductase family type II enzyme, molybdopterin subunit/0.446
5k2bZMAAdenosine receptor A2a/0.446
3sn6P0GBeta-2 adrenergic receptor/0.446
1a9sNOSPurine nucleoside phosphorylase2.4.2.10.445
1db56INPhospholipase A2, membrane associated/0.445
1i59ADPChemotaxis protein CheA2.7.13.30.445
1ie8KH1Vitamin D3 receptor/0.445
1jpaANPEphrin type-B receptor 22.7.10.10.445
1jtuLYBThymidylate synthase/0.445
1pu9COAHAT A1/0.445
1qorNDPQuinone oxidoreductase 1/0.445
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.445
1uhhCZPAequorin-2/0.445
1xm1GAHProthrombin3.4.21.50.445
1xu9CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.445
2aclL05Oxysterols receptor LXR-alpha/0.445
2anmCDOProthrombin3.4.21.50.445
2gjlFMNNitronate monooxygenase1.13.12.160.445
2hvdADPNucleoside diphosphate kinase A2.7.4.60.445
2q28ADPOxalyl-CoA decarboxylase4.1.1.80.445
2v59LZKBiotin carboxylase6.3.4.140.445
2vbpVB1Isopenicillin N synthase1.21.3.10.445
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.445
2y035FWBeta-1 adrenergic receptor/0.445
2yhuWHFPteridine reductase/0.445
2zf051UProthrombin3.4.21.50.445
3exnACOProbable acetyltransferase/0.445
3h3r14HCollagen type IV alpha-3-binding protein/0.445
3ho2N323-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.445
3hz5Z64Heat shock protein HSP 90-alpha/0.445
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.445
3tk3CPZCytochrome P450 2B41.14.14.10.445
3zhuTD8Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.445
4at0FADPossible succinate dehydrogenase/0.445
4b5pACOAlpha-tubulin N-acetyltransferase 1/0.445
4bmpFMNProtein NrdI/0.445
4ceqQCHIntegrase/0.445
4dtiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
4gts7TPGeranylgeranyl transferase type-2 subunit beta2.5.1.600.445
4hlg20BTankyrase-22.4.2.300.445
4hvs647Mast/stem cell growth factor receptor Kit2.7.10.10.445
4itfTFYVitamin D3 receptor/0.445
4jln18VDeoxycytidine kinase2.7.1.740.445
4m4821BSodium-dependent dopamine transporter/0.445
4mr61K0Bromodomain-containing protein 2/0.445
4okt198Androgen receptor/0.445
4oxyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
4q03GDPGTPase KRas/0.445
4rtpSAMDNA adenine methylase2.1.1.720.445
4ubuCOASteroid 3-ketoacyl-CoA thiolase/0.445
4wevSUZAldo-keto reductase family 1 member B101.1.10.445
4xt5NAPPossible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc/0.445
5ab6CAANonspecific lipid-transfer protein, putative/0.445
5kjcPFBAlcohol dehydrogenase E chain1.1.1.10.445
1c7oPPGHemolysin/0.444
1ix1BB2Peptide deformylase/0.444
1j3kWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.444
1ju2FAD(R)-mandelonitrile lyase 24.1.2.100.444
1jwtBLIProthrombin3.4.21.50.444
1kzjCB3Thymidylate synthase/0.444
1mvtDTMDihydrofolate reductase1.5.1.30.444
1nhkCMPNucleoside diphosphate kinase2.7.4.60.444
1pwyAC2Purine nucleoside phosphorylase2.4.2.10.444
1qzfCB3Bifunctional dihydrofolate reductase-thymidylate synthase/0.444
1rejB1LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
1vj3TABDihydrofolate reductase1.5.1.30.444
1vyrFMNPentaerythritol tetranitrate reductase/0.444
1w06W05Isopenicillin N synthase1.21.3.10.444
1ws1BB2Peptide deformylase 1/0.444
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.444
1zgv501Prothrombin3.4.21.50.444
1zprCB3Thymidylate synthase/0.444
2a1oCAMCamphor 5-monooxygenase1.14.15.10.444
2dy9ADPNucleoside diphosphate kinase2.7.4.60.444
2e9dB76Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.444
2g1pSAHDNA adenine methylase2.1.1.720.444
2o7pNAPRiboflavin biosynthesis protein RibD/0.444
2p83MR0Beta-secretase 13.4.23.460.444
2q9fC3SCholesterol 24-hydroxylase/0.444
2v3wTPPBenzoylformate decarboxylase4.1.1.70.444
2wggTLM3-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.444
2x6o2TCTetracycline repressor protein class D/0.444
2y60M8FIsopenicillin N synthase1.21.3.10.444
3akm11DFatty acid-binding protein, intestinal/0.444
3bl7DD1m7GpppX diphosphatase3.6.1.590.444
3czr3CZCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3ed1GA3Gibberellin receptor GID1/0.444
3h3qH13Collagen type IV alpha-3-binding protein/0.444
3hatGLY_VAL_ARG_RNGProthrombin3.4.21.50.444
3hy7097A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.444
3i0rRT3Gag-Pol polyprotein2.7.7.490.444
3i8p8403-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.444
3lfm3DTAlpha-ketoglutarate-dependent dioxygenase FTO/0.444
3sigAR6Uncharacterized protein/0.444
3tptADPSerine/threonine-protein kinase toxin HipA/0.444
3uq9TBNPutative adenosine kinase/0.444
4bqyFNTEgl nine homolog 1/0.444
4foxUMPThymidylate synthase ThyA/0.444
4fxy0W2Neurolysin, mitochondrial3.4.24.160.444
4hxyNDPPlm1/0.444
4iarERM5-hydroxytryptamine receptor 1B/0.444
4mv8ACPBiotin carboxylase6.3.4.140.444
4qaiFMNNADPH dehydrogenase/0.444
5d7q4I5NAD-dependent protein deacetylase sirtuin-23.5.10.444
1a5sFIPTryptophan synthase alpha chain/0.443
1drhNAPDihydrofolate reductase1.5.1.30.443
1f5fDHTSex hormone-binding globulin/0.443
1f8gNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.443
1h83FADPolyamine oxidase1.5.3.140.443
1k22MELProthrombin3.4.21.50.443
1klkPMDDihydrofolate reductase1.5.1.30.443
1l2tATPUncharacterized ABC transporter ATP-binding protein MJ0796/0.443
1m52P17Tyrosine-protein kinase ABL12.7.10.20.443
1mczRMNBenzoylformate decarboxylase4.1.1.70.443
1mvsDTMDihydrofolate reductase1.5.1.30.443
1pw1HELD-alanyl-D-alanine carboxypeptidase3.4.16.40.443
1szgFNSCytochrome b2, mitochondrial1.1.2.30.443
1xp8AGSProtein RecA/0.443
2bu9HFVIsopenicillin N synthase1.21.3.10.443
2cdaNAPGlucose 1-dehydrogenase/0.443
2f3mGTDGlutathione S-transferase Mu 12.5.1.180.443
2iviACWIsopenicillin N synthase1.21.3.10.443
2ow9SP6Collagenase 33.4.240.443
2z7gEH9Adenosine deaminase3.5.4.40.443
3ac2KSETyrosine-protein kinase Lck2.7.10.20.443
3invC50Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.443
3lkhLT6Genome polyprotein2.7.7.480.443
3mauEXTPutative sphingosine-1-phosphate lyase/0.443
3s55NADPutative short-chain dehydrogenase/reductase/0.443
4ddrMMVDihydrofolate reductase1.5.1.30.443
4dmgSAMUncharacterized protein/0.443
4fj0HHF17beta-hydroxysteroid dehydrogenase/0.443
4gki0JNAminoglycoside 3'-phosphotransferase AphA1-IAB/0.443
4jnc1LFBifunctional epoxide hydrolase 23.1.3.760.443
4jv81M1Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.443
4nh82LCHeat shock protein HSP 90-alpha/0.443
4rww2BALmo2692 protein/0.443
4u0sADPAdenosine monophosphate-protein transferase FICD2.7.7.n10.443
5agyGTBTau class glutathione S-transferase/0.443
1afeALZProthrombin3.4.21.50.442
1dg5TOPDihydrofolate reductase1.5.1.30.442
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.442
1n83CLRNuclear receptor ROR-alpha/0.442
1pydTDPPyruvate decarboxylase isozyme 1/0.442
1qtiGNTAcetylcholinesterase3.1.1.70.442
1ry0PG2Aldo-keto reductase family 1 member C3/0.442
1s3vTQDDihydrofolate reductase1.5.1.30.442
1t7rDHTAndrogen receptor/0.442
1tl7ONMAdenylate cyclase type 2/0.442
1tl7ONMAdenylate cyclase type 5/0.442
1wnz2VAIsoleucine--tRNA ligase6.1.1.50.442
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
1y5rC0RCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.442
1yinCM3Estrogen receptor/0.442
1yl7NAI4-hydroxy-tetrahydrodipicolinate reductase/0.442
2b04CHOPhospholipase A2, major isoenzyme3.1.1.40.442
2braFAD[F-actin]-methionine sulfoxide oxidase MICAL11.14.130.442
2cf8ESHProthrombin3.4.21.50.442
2d3aADPGlutamine synthetase root isozyme 36.3.1.20.442
2g44T3OEstrogen receptor/0.442
2itvANPEpidermal growth factor receptor2.7.10.10.442
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.442
2pogWSTEstrogen receptor/0.442
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.442
2w3mFOLDihydrofolate reductase1.5.1.30.442
2wgjVGHHepatocyte growth factor receptor2.7.10.10.442
3a783EVVitamin D3 receptor/0.442
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.442
3etdNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.442
3ghh2NFCD38 molecule/0.442
3m6pBB2Peptide deformylase 1B, chloroplastic/mitochondrial3.5.1.880.442
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
3vi5M4MHematopoietic prostaglandin D synthase/0.442
4ap7F47Hepatocyte growth factor receptor2.7.10.10.442
4baqM4ZProthrombin3.4.21.50.442
4eqsCOACoenzyme A disulfide reductase/0.442
4fflADPUncharacterized protein/0.442
4g3jVNTLanosterol 14-alpha-demethylase/0.442
4ho8THMGlucose-1-phosphate thymidylyltransferase/0.442
4iskUMPThymidylate synthase/0.442
4l435FIRibosomal protein S6 kinase beta-12.7.11.10.442
4ly91YYGlucokinase regulatory protein/0.442
4otyLURProstaglandin G/H synthase 21.14.99.10.442
4rtkSAHDNA adenine methylase2.1.1.720.442
4uugPXGBranched-chain amino acid aminotransferase, putative/0.442
4wudANPDNA gyrase subunit B/0.442
4yp6NAPNicotinamide-nucleotide adenylyltransferase2.7.7.10.442
5ejaTD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.442
5il2SAHN6-adenosine-methyltransferase 70 kDa subunit/0.442
4phu2YBFree fatty acid receptor 1/0.442
1crbRTLRetinol-binding protein 1/0.441
1dr5NAPDihydrofolate reductase1.5.1.30.441
1e7aPFLSerum albumin/0.441
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.441
1fmlRTLRetinol dehydratase/0.441
1gnwGTXGlutathione S-transferase F22.5.1.180.441
1iyzNDPProbable quinone oxidoreductase/0.441
1kw9BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.441
1ludTRRDihydrofolate reductase1.5.1.30.441
1qf4RPDAdenylosuccinate synthetase/0.441
1re0AFBADP-ribosylation factor 1/0.441
1re0AFBARF guanine-nucleotide exchange factor 1/0.441
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
1tduCB3Thymidylate synthase/0.441
1uy9PU6Heat shock protein HSP 90-alpha/0.441
1vcfFMNIsopentenyl-diphosphate delta-isomerase/0.441
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.441
1ygkRRCPyridoxal kinase2.7.1.350.441
2bfpH4BPteridine reductase 11.5.1.330.441
2c31TZDOxalyl-CoA decarboxylase4.1.1.80.441
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.441
2qqfA1RNAD-dependent protein deacetylase HST23.5.10.441
2tpsTPSThiamine-phosphate synthase/0.441
2v0uFMNNPH1-1/0.441
2vkeTACTetracycline repressor protein class D/0.441
2yozOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.441
2ywlFADThioredoxin reductase related protein/0.441
2zwaSAHtRNA wybutosine-synthesizing protein 42.1.1.2900.441
3bgxMEFThymidylate synthase/0.441
3cib314Beta-secretase 13.4.23.460.441
3dh7FMNIsopentenyl-diphosphate delta-isomerase/0.441
3fktSIIBeta-secretase 13.4.23.460.441
3ha5SFGHydroxymycolate synthase MmaA42.1.10.441
3kudGDPGTPase HRas/0.441
3n8yDIFProstaglandin G/H synthase 11.14.99.10.441
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3rq6APRADP-dependent (S)-NAD(P)H-hydrate dehydratase/0.441
3sfy3FYUncharacterized protein/0.441
3u9y09LTankyrase-22.4.2.300.441
3v3m0ENReplicase polyprotein 1a3.4.19.120.441
3w0gW07Vitamin D3 receptor/0.441
4bbyFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.441
4c1fX8ZMetallo-beta-lactamase type 2/0.441
4dvi2IWTankyrase-12.4.2.300.441
4eueNAITrans-2-enoyl-CoA reductase [NADH]/0.441
4i09CMPcAMP-activated global transcriptional regulator CRP/0.441
4j7xSASSepiapterin reductase1.1.1.1530.441
4jlm1NNDeoxycytidine kinase2.7.1.740.441
4lb2DM5Serum albumin/0.441
4mv1ADPBiotin carboxylase6.3.4.140.441
4rrkA3TProbable threonine--tRNA ligase 26.1.1.30.441
4wbdADPPutative cysteine ligase BshC/0.441
4x5gFOLDihydrofolate reductase1.5.1.30.441
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.441
5d1bTSNHistone deacetylase 83.5.1.980.441
5iqgGDPBifunctional AAC/APH2.3.10.441
5k2cZMAAdenosine receptor A2a/0.441
1dkfBMSRetinoic acid receptor alpha/0.440
1fduNAPEstradiol 17-beta-dehydrogenase 11.1.1.620.440
1i75NOJCyclomaltodextrin glucanotransferase2.4.1.190.440
1j7kATPHolliday junction ATP-dependent DNA helicase RuvB/0.440
1j8uH4BPhenylalanine-4-hydroxylase1.14.16.10.440
1kvkATPMevalonate kinase2.7.1.360.440
1n2vBDIQueuine tRNA-ribosyltransferase2.4.2.290.440
1ogxEQUSteroid Delta-isomerase5.3.3.10.440
1ppjANYCytochrome b/0.440
1tllFADNitric oxide synthase, brain1.14.13.390.440
1u1cBAUUridine phosphorylase2.4.2.30.440
1zrb062Prothrombin3.4.21.50.440
2bswCAOProbable acetyltransferase/0.440
2clhF19Tryptophan synthase alpha chain/0.440
2ihvTPPN(2)-(2-carboxyethyl)arginine synthase/0.440
2j83BATUlilysin3.4.240.440
2jddACOProbable acetyltransferase/0.440
2jh0701Prothrombin3.4.21.50.440
2jh6894Prothrombin3.4.21.50.440
2pioDHTAndrogen receptor/0.440
2po7CHDFerrochelatase, mitochondrial4.99.1.10.440
2v3hI25Prothrombin3.4.21.50.440
2z4bDC8Estrogen receptor beta/0.440
2zfp19UProthrombin3.4.21.50.440
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
3gluLYS_VAL_METNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.440
3nn6HNK6-hydroxy-L-nicotine oxidase/0.440
3o8gO8GHTH-type transcriptional regulator EthR/0.440
3o96IQORAC-alpha serine/threonine-protein kinase2.7.11.10.440
3um5CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.440
3wleNAD(R)-specific carbonyl reductase/0.440
3zoiM2WIsopenicillin N synthase1.21.3.10.440
4a802ANMajor pollen allergen Bet v 1-A/0.440
4bqwQNMEgl nine homolog 1/0.440
4dlbNADS-(hydroxymethyl)glutathione dehydrogenase/0.440
4dlvGNPGTPase HRas/0.440
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.440
4h6pFMNChromate reductase/0.440
4usqFADPyridine nucleotide-disulfide oxidoreductase/0.440
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.440
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.440
4y9lFADAcyl-CoA dehydrogenase family member 11/0.440
5aqzSGVHeat shock 70 kDa protein 1A/0.440
5c1mCLRMu-type opioid receptor/0.440
5cmx0G6Prothrombin3.4.21.50.440
4k5y1Q5Corticotropin-releasing factor receptor 1/0.440
4zj8SUVOrexin receptor type 1/0.440