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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2yi5YI5Heat shock protein HSP 90-alpha

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
2yi5YI5Heat shock protein HSP 90-alpha/1.000
1u0zRDCEndoplasmin/0.651
3hhu819Heat shock protein HSP 90-alpha/0.639
2breKJ2ATP-dependent molecular chaperone HSP82/0.630
3ekoPYUHeat shock protein HSP 90-alpha/0.629
2qg0A94Heat shock protein HSP 90-alpha/0.624
2bz5AB4Heat shock protein HSP 90-alpha/0.623
3ekrPY9Heat shock protein HSP 90-alpha/0.622
3k99PFTHeat shock protein HSP 90-alpha/0.620
1yc14BCHeat shock protein HSP 90-alpha/0.617
3r4pFU7Heat shock protein HSP 90-alpha/0.617
2iwxM1SATP-dependent molecular chaperone HSP82/0.613
1bgqRDCATP-dependent molecular chaperone HSP82/0.612
2yegXQGHeat shock protein HSP 90-alpha/0.609
3r4nFU5Heat shock protein HSP 90-alpha/0.609
2hg1N5OEndoplasmin/0.608
4fcr0TMHeat shock protein HSP 90-alpha/0.608
2qfoA13Heat shock protein HSP 90-alpha/0.606
3rlr3RRHeat shock protein HSP 90-alpha/0.605
3rlq3RQHeat shock protein HSP 90-alpha/0.604
2fypRDEEndoplasmin/0.601
3b28B2XHeat shock protein HSP 90-alpha/0.596
1qy8RDIEndoplasmin/0.591
3k974CDHeat shock protein HSP 90-alpha/0.591
2bt0CT5Heat shock protein HSP 90-alpha/0.590
2gfdRDAEndoplasmin/0.587
1u0yPA7Endoplasmin/0.586
1yszNECEndoplasmin/0.584
2wepADPATP-dependent molecular chaperone HSP82/0.582
2werRDCATP-dependent molecular chaperone HSP82/0.582
2qfoA51Heat shock protein HSP 90-alpha/0.581
2xabVHDHeat shock protein HSP 90-alpha/0.580
2xhrC0PHeat shock protein HSP 90-alpha/0.580
4bqjXKLHeat shock protein HSP 90-alpha/0.579
4ce17FKATP-dependent molecular chaperone HSP82/0.578
2xx213CATP-dependent molecular chaperone HSP82/0.577
3vhaVHAHeat shock protein HSP 90-alpha/0.577
2xx413IATP-dependent molecular chaperone HSP82/0.576
1am1ADPATP-dependent molecular chaperone HSP82/0.574
2wi6ZZ6Heat shock protein HSP 90-alpha/0.572
4ce2BO5ATP-dependent molecular chaperone HSP82/0.572
2byh2D7Heat shock protein HSP 90-alpha/0.571
2xk2ADPHeat shock protein HSP 90-alpha/0.570
3k981RCHeat shock protein HSP 90-alpha/0.569
1qy5NECEndoplasmin/0.567
1u2oNECEndoplasmin/0.567
2gqpPA7Endoplasmin/0.567
3hekBD0Heat shock protein HSP 90-alpha/0.567
1yc34BCHeat shock protein HSP 90-alpha/0.565
2iwuNP5ATP-dependent molecular chaperone HSP82/0.563
2brcCT5ATP-dependent molecular chaperone HSP82/0.562
3whaWHAHeat shock protein HSP 90-alpha/0.560
1uydPU8Heat shock protein HSP 90-alpha/0.557
4xcjADPHeat shock cognate 90 kDa protein/0.555
3hz5Z64Heat shock protein HSP 90-alpha/0.554
4jqlVJ6Heat shock protein HSP 90-alpha/0.553
3hz142CHeat shock protein HSP 90-alpha/0.552
1uymPU3Heat shock protein HSP 90-beta/0.551
2yefANPHeat shock protein HSP 90-alpha/0.550
2fxsRDAATP-dependent molecular chaperone HSP82/0.547
3iedAN2HSP90/0.547
3r4oFU3Heat shock protein HSP 90-alpha/0.547
2cgfP2NATP-dependent molecular chaperone HSP82/0.546
2vw5BC6ATP-dependent molecular chaperone HSP82/0.544
2xd6XD6ATP-dependent molecular chaperone HSP82/0.542
4xc0ACPHeat shock cognate 90 kDa protein/0.541
1yt0ADPEndoplasmin/0.540
3pehIBDEndoplasmin homolog, putative/0.540
1y4sADPChaperone protein HtpG/0.539
3hyz42CHeat shock protein HSP 90-alpha/0.539
2byi2DDHeat shock protein HSP 90-alpha/0.537
3c11GDMATP-dependent molecular chaperone HSP82/0.536
3t10ACPHeat shock protein HSP 90-alpha/0.534
4ce3L4VATP-dependent molecular chaperone HSP82/0.534
1osfKOSHeat shock protein HSP 90-alpha/0.533
4egiB2JHeat shock protein HSP 90-alpha/0.533
1uy7PU4Heat shock protein HSP 90-alpha/0.532
4gqtADPHeat shock protein 90/0.532
5f5rANPHeat shock protein 75 kDa, mitochondrial/0.532
3t1kANPHeat shock protein HSP 90-alpha/0.531
4eftEFTHeat shock protein HSP 90-alpha/0.530
3t2sAGSHeat shock protein HSP 90-alpha/0.529
2yee2ECHeat shock protein HSP 90-alpha/0.528
1yetGDMHeat shock protein HSP 90-alpha/0.527
3pejBC2Endoplasmin homolog, putative/0.516
4dbzNDPPutative ketoacyl reductase1.3.10.515
1uycPU7Heat shock protein HSP 90-alpha/0.512
3d0bSNXHeat shock protein HSP 90-alpha/0.512
2xjxXJXHeat shock protein HSP 90-alpha/0.510
2exlGDMEndoplasmin/0.509
2bu8ADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.508
2yeiXQIHeat shock protein HSP 90-alpha/0.506
1byqADPHeat shock protein HSP 90-alpha/0.505
2b378PSEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.505
1xddAAYIntegrin alpha-L/0.503
1bwsNDPGDP-L-fucose synthase/0.502
2xcmADPCytosolic heat shock protein 90/0.501
1amwADPATP-dependent molecular chaperone HSP82/0.500
2o1uANPEndoplasmin/0.500
3t0zATPHeat shock protein HSP 90-alpha/0.499
2q8iRDC[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial2.7.11.20.496
2xhtC0YHeat shock protein HSP 90-alpha/0.496
3so9017Pol protein/0.496
4egkRDCHeat shock protein HSP 90-alpha/0.496
4xclAGSHeat shock cognate 90 kDa protein/0.493
4xdmGDMHeat shock cognate 90 kDa protein/0.493
2yejXQKHeat shock protein HSP 90-alpha/0.491
4ew3DXZTrifunctional purine biosynthetic protein adenosine-32.1.2.20.490
4e4qRRHPeroxisome proliferator-activated receptor gamma/0.489
2wi5ZZ5Heat shock protein HSP 90-alpha/0.488
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.488
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.486
2yejZZ3Heat shock protein HSP 90-alpha/0.486
2iwsNP4ATP-dependent molecular chaperone HSP82/0.485
4as94QSATP-dependent molecular chaperone HSP82/0.485
1lf2R37Plasmepsin-23.4.23.390.484
1rd4L08Integrin alpha-L/0.484
2z0ySAMRibosomal RNA small subunit methyltransferase E/0.484
3eigMTXDihydrofolate reductase1.5.1.30.484
4asf62UATP-dependent molecular chaperone HSP82/0.484
4oztP1AEcdysone receptor, putative/0.484
1ohhANPATP synthase subunit alpha, mitochondrial/0.483
1ohhANPATP synthase subunit beta, mitochondrial3.6.3.140.483
3n7uNADFormate dehydrogenase, chloroplastic/mitochondrial/0.483
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.482
3l0lHC3Nuclear receptor ROR-gamma/0.481
4asg814ATP-dependent molecular chaperone HSP82/0.481
1rx8NAPDihydrofolate reductase1.5.1.30.480
1xe55FEPlasmepsin-23.4.23.390.480
2vwqNAPGlucose 1-dehydrogenase/0.480
3mjrAC2Deoxycytidine kinase2.7.1.740.480
4l6gCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.480
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.479
3invNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.479
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.478
3fpzAHZThiamine thiazole synthase/0.478
3o9bK2APol polyprotein/0.478
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.478
1h74AGSHomoserine kinase2.7.1.390.477
1pdhFASp-hydroxybenzoate hydroxylase/0.477
2zdxP4A[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial2.7.11.20.477
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.477
1cqp803Integrin alpha-L/0.476
2xx513NATP-dependent molecular chaperone HSP82/0.476
2ykiYKIHeat shock protein HSP 90-alpha/0.476
3gfbNADL-threonine 3-dehydrogenase/0.476
4nh82LCHeat shock protein HSP 90-alpha/0.476
4q0kGA3Phytohormone-binding protein/0.476
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.475
3pt6SAHDNA (cytosine-5)-methyltransferase 12.1.1.370.475
3r83Z14Cyclin-dependent kinase 22.7.11.220.475
4z1fH71Heat shock protein 75 kDa, mitochondrial/0.475
2ignFADPyranose 2-oxidase/0.474
2npxNADNADH peroxidase1.11.1.10.474
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.474
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.474
3toh079Gag-Pol polyprotein2.7.7.490.474
5fwnNAPPutative dehydrogenase/0.474
1nhhANPDNA mismatch repair protein MutL/0.473
4e9aQAPPeptide deformylase/0.473
4jauADPSensor histidine kinase/0.473
4lxhC1EAlpha/beta hydrolase fold/0.473
1diuBDMDihydrofolate reductase1.5.1.30.472
1ep1FMNDihydroorotate dehydrogenase B (NAD(+)), catalytic subunit1.3.1.140.472
1vikBAYGag-Pol polyprotein/0.472
2bfqAR6[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.472
2nniMTKCytochrome P450 2C8/0.472
2vbdV10Isopenicillin N synthase1.21.3.10.472
2vwcBC2ATP-dependent molecular chaperone HSP82/0.472
3aw9NADNAD-dependent epimerase/dehydratase/0.472
3beoUD1UDP-N-acetylglucosamine 2-epimerase/0.472
3bvb017Gag-Pol polyprotein3.4.23.160.472
3cyxROCGag-Pol polyprotein3.4.23.160.472
5eccNAPDehydrofolate reductase type I/0.472
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.471
1xe65FPPlasmepsin-23.4.23.390.471
2esaGDMEndoplasmin/0.471
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.471
3lsmSFDPyranose 2-oxidase/0.471
3o9dK19Pol polyprotein/0.471
4hbgNDP3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.471
4k28NADShikimate dehydrogenase family protein/0.471
4oj4DIFPeroxisome proliferator-activated receptor gamma/0.471
5cccDDFDihydrofolate reductase1.5.1.30.471
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.470
1qrpHH0Pepsin A-43.4.23.10.470
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.470
2qhzMZ2Gag-Pol polyprotein/0.470
3dckKVIProtease/0.470
4an4DUDPutative glycosyl transferase/0.470
4fv7E94Mitogen-activated protein kinase 12.7.11.240.470
5a88ADPRiboflavin biosynthesis protein RibF2.7.1.260.470
2v2zCDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.469
3dv3MEKDual specificity mitogen-activated protein kinase kinase 12.7.12.20.469
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.469
1dnpFADDeoxyribodipyrimidine photo-lyase4.1.99.30.468
1n49RITGag-Pol polyprotein3.4.23.160.468
1qbt146Gag-Pol polyprotein3.4.23.160.468
2bu2ATP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.468
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.468
2hw2RFPRifampin ADP-ribosyl transferase/0.468
1r2jFADFkbI/0.467
2briANPUridylate kinase2.7.4.220.467
3d1xROCGag-Pol polyprotein3.4.23.160.467
3hx4ANPCalmodulin-domain protein kinase 1/0.467
3zkdANPDNA gyrase subunit B/0.467
1e79ATPATP synthase subunit alpha, mitochondrial/0.466
1e79ATPATP synthase subunit beta, mitochondrial3.6.3.140.466
3o0iP54Heat shock protein HSP 90-alpha/0.466
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.466
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.466
4l8u9AZSerum albumin/0.466
4njvRITProtease/0.466
1hvlA76Gag-Pol polyprotein/0.465
1me8RVPInosine-5'-monophosphate dehydrogenase/0.465
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.465
1qo8FADFumarate reductase flavoprotein subunit/0.465
2hfuMEVMevalonate kinase/0.465
2y99NADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase1.3.1.560.465
3gggNADPrephenate dehydrogenase/0.465
3gwfFADCyclohexanone monooxygenase/0.465
3lpjZ75Beta-secretase 13.4.23.460.465
3lzu017Gag-Pol polyprotein3.4.23.160.465
3mxdK53Gag-Pol polyprotein3.4.23.160.465
3nxxNDPDihydrofolate reductase1.5.1.30.465
3upf0BUPolyprotein/0.465
3v3m0ENReplicase polyprotein 1a3.4.19.120.465
4a862ANMajor pollen allergen Bet v 1-A/0.465
4rnuFMNNADPH dehydrogenase 11.6.99.10.465
1ay0TPPTransketolase 12.2.1.10.464
1gqtACPRibokinase/0.464
1h74ADPHomoserine kinase2.7.1.390.464
1i59ANPChemotaxis protein CheA2.7.13.30.464
1mtrPI6Gag-Pol polyprotein3.4.23.160.464
2c27ACOMycothiol acetyltransferase2.3.1.1890.464
2ew5Y12Peptide deformylase/0.464
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.464
2hchN5AEndoplasmin/0.464
3atyFMNProstaglandin F2a synthase/0.464
3gqvNAPEnoyl reductase LovC10.464
4ie6UN9Alpha-ketoglutarate-dependent dioxygenase FTO/0.464
1m75CAAHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.463
2pncCLUPrimary amine oxidase, liver isozyme/0.463
3b2eADPATPase GET3/0.463
3lxpIZANon-receptor tyrosine-protein kinase TYK22.7.10.20.463
3tscNADUncharacterized protein/0.463
4a8v2ANMajor pollen allergen Bet v 1-J/0.463
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
4ienCOAPutative acyl-CoA hydrolase/0.463
4q1y017Gag-Pol polyprotein3.4.23.160.463
5a9sNAPPutative dehydrogenase/0.463
1bdlIM1Gag-Pol polyprotein3.4.23.160.462
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.462
1dirNADDihydropteridine reductase1.5.1.340.462
1i5zCMPcAMP-activated global transcriptional regulator CRP/0.462
1kp2ATPArgininosuccinate synthase6.3.4.50.462
2a94AP0L-lactate dehydrogenase1.1.1.270.462
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.462
2g8yNADHydroxycarboxylate dehydrogenase B/0.462
2p9cNAID-3-phosphoglycerate dehydrogenase1.1.1.950.462
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.462
2wbdRO5Fructose-1,6-bisphosphatase 13.1.3.110.462
2xtnGTPGTPase IMAP family member 2/0.462
3b70NAPEnoyl reductase LovC10.462
3cgcCOACoenzyme A disulfide reductase/0.462
3lsiFADPyranose 2-oxidase/0.462
3pj8404Cyclin-dependent kinase 22.7.11.220.462
3s56ROCProtease/0.462
3uoyNAP2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.462
4gk3L87Ephrin type-A receptor 32.7.10.10.462
4hxyNDPPlm1/0.462
4m11MXMProstaglandin G/H synthase 21.14.99.10.462
4m4922YL-lactate dehydrogenase A chain1.1.1.270.462
4o71CPBBromodomain-containing protein 4/0.462
5c77SAHProtein arginine N-methyltransferase SFM1/0.462
1a72PADAlcohol dehydrogenase E chain1.1.1.10.461
1adfTADAlcohol dehydrogenase E chain1.1.1.10.461
1dyiFOLDihydrofolate reductase1.5.1.30.461
1fgc2NCGag-Pol polyprotein3.4.23.160.461
1x1bSAHC-20 methyltransferase/0.461
1z1rHBHGag-Pol polyprotein3.4.23.160.461
2hkjRDCType 2 DNA topoisomerase 6 subunit B/0.461
3lzs017Gag-Pol polyprotein3.4.23.160.461
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.461
3o9iA61Gag-Pol polyprotein/0.461
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.461
4kp71UQ1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.461
4oaeCLMUncharacterized protein/0.461
1drfFOLDihydrofolate reductase1.5.1.30.460
1f5fDHTSex hormone-binding globulin/0.460
1hbvGANGag-Pol polyprotein/0.460
1qiqACCIsopenicillin N synthase1.21.3.10.460
1vsvNADGlyceraldehyde-3-phosphate dehydrogenase/0.460
1w0kADPATP synthase subunit alpha, mitochondrial/0.460
1w0kADPATP synthase subunit beta, mitochondrial3.6.3.140.460
2bfrADP[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.460
2eauCZASarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.460
2ejzSAHDiphthine synthase/0.460
2he5NDPAldo-keto reductase family 1 member C211.1.10.460
2rcyNAPPyrroline-5-carboxylate reductase/0.460
2w6zL21Biotin carboxylase6.3.4.140.460
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.460
3fhxPLPPyridoxal kinase2.7.1.350.460
3sa6F71Protease/0.460
3u8k09PAcetylcholine-binding protein/0.460
4fc7NAPPeroxisomal 2,4-dienoyl-CoA reductase1.3.1.340.460
4mgiCMPRap guanine nucleotide exchange factor 4/0.460
4xj3GTPCyclic GMP-AMP synthase/0.460
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.460
1eyqNARChalcone--flavonone isomerase 15.5.1.60.459
1hvkA79Gag-Pol polyprotein/0.459
1jm6ADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.459
1zdwFLVPrenyltransferase/0.459
2b53D23Cyclin-dependent kinase 22.7.11.220.459
2b7aIZATyrosine-protein kinase JAK2/0.459
2e0nSAHPrecorrin-2 C20-methyltransferase/0.459
2pckSAHDiphthine synthase/0.459
2vcmM11Isopenicillin N synthase1.21.3.10.459
2wugHPK4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.459
2z97CAMCamphor 5-monooxygenase1.14.15.10.459
2zjwREFCasein kinase II subunit alpha2.7.11.10.459
3ha5SFGHydroxymycolate synthase MmaA42.1.10.459
3imgBZ3Pantothenate synthetase6.3.2.10.459
3kgaLX9MAP kinase-activated protein kinase 22.7.11.10.459
3qlrNDPDihydrofolate reductase1.5.1.30.459
3rdqDTBStreptavidin/0.459
4nd4NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.459
1ahiCHO7-alpha-hydroxysteroid dehydrogenase1.1.1.1590.458
1blzACVIsopenicillin N synthase1.21.3.10.458
1dyhDZFDihydrofolate reductase1.5.1.30.458
1kqgMGDFormate dehydrogenase, nitrate-inducible, major subunit1.1.5.60.458
1lf3EH5Plasmepsin-23.4.23.390.458
1orrNADCDP-paratose 2-epimerase/0.458
1rdwLARActin, alpha skeletal muscle/0.458
1yrdCAMCamphor 5-monooxygenase1.14.15.10.458
2jh6894Prothrombin3.4.21.50.458
2owkSAHDiphthine synthase/0.458
2p9gNAID-3-phosphoglycerate dehydrogenase1.1.1.950.458
2wd8VGFPteridine reductase/0.458
2x0iNAIMalate dehydrogenase/0.458
2znq401Peroxisome proliferator-activated receptor delta/0.458
3cgeNDPCoenzyme A disulfide reductase/0.458
3el01UNGag-Pol polyprotein3.4.23.160.458
3hbbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.458
3qlsNDPDihydrofolate reductase1.5.1.30.458
4a61ANPPlasmid segregation protein ParM/0.458
4l4bCAMCamphor 5-monooxygenase1.14.15.10.458
4mihFADPyranose 2-oxidase1.1.3.100.458
1e3eNAIAlcohol dehydrogenase 41.1.1.10.457
1rb3MTXDihydrofolate reductase1.5.1.30.457
1y7lASN_LEU_ASN_ILECysteine synthase2.5.1.470.457
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.457
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.457
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.457
3cid318Beta-secretase 13.4.23.460.457
3d2rADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial2.7.11.20.457
3fklFKLMitogen-activated protein kinase 14/0.457
3ii43IIDihydrolipoyl dehydrogenase1.8.1.40.457
3o9gF53Gag-Pol polyprotein/0.457
3oct1N1Tyrosine-protein kinase BTK2.7.10.20.457
3orfNADDihydropteridine reductase1.5.1.340.457
3r4b74TGag-Pol polyprotein/0.457
3sa4F72Protease/0.457
3t3r9PLCytochrome P450 2A61.14.130.457
4a31MYAGlycylpeptide N-tetradecanoyltransferase/0.457
4b4dFADFerredoxin-NADP reductase/0.457
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.457
4dc0NDPPutative ketoacyl reductase1.3.10.457
4e2dFMNDehydrogenase/0.457
4r20AERCytochrome P450 family 17 polypeptide 2/0.457
4uyf73BBromodomain-containing protein 2/0.457
1b6kPI5Gag-Pol polyprotein3.4.23.160.456
1gadNADGlyceraldehyde-3-phosphate dehydrogenase A/0.456
1h50FMNPentaerythritol tetranitrate reductase/0.456
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.456
1j0xNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.456
1kfcIPLTryptophan synthase alpha chain/0.456
1t2bCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.456
1yt9OISGag-Pol polyprotein/0.456
1zsf0ZSGag-Pol polyprotein3.4.23.160.456
2e15SAHDiphthine synthase/0.456
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.456
2pb6SAHDiphthine synthase/0.456
2tpsTPSThiamine-phosphate synthase/0.456
2vzzSCAPutative succinyl-CoA transferase Rv0802c2.8.30.456
3bg7FADPyranose 2-oxidase/0.456
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.456
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.456
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4gmy0X5Tyrosine-protein kinase JAK2/0.456
4klaCHDFerrochelatase, mitochondrial4.99.1.10.456
4nmbFADBifunctional protein PutA/0.456
1d4pBPPProthrombin3.4.21.50.455
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.455
1idb0DOGag-Pol polyprotein/0.455
1j3jNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.455
1pq944BOxysterols receptor LXR-beta/0.455
1z59ADPType 2 DNA topoisomerase 6 subunit B/0.455
2a1tFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.455
2a4fAAUV-1 protease/0.455
2gcqDOIAdenylosuccinate synthetase/0.455
2ibzUQ6Cytochrome b/0.455
2ozuACOHistone acetyltransferase KAT6A/0.455
2p5fSAHDiphthine synthase/0.455
2qbmCAMCamphor 5-monooxygenase1.14.15.10.455
3a20FMNFMN-binding protein/0.455
3ekv478Gag-Pol polyprotein3.4.23.160.455
3eyhIZATyrosine-protein kinase JAK1/0.455
3tog079Gag-Pol polyprotein2.7.7.490.455
4fncHMUG/T mismatch-specific thymine DNA glycosylase3.2.2.290.455
4g2gTDHMycocyclosin synthase1.14.21.90.455
4hj6FMNLOV protein/0.455
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.455
4j1tNADNAD/NADP transhydrogenase alpha subunit 1/0.455
4yp6NAPNicotinamide-nucleotide adenylyltransferase2.7.7.10.455
1b8uNADMalate dehydrogenase/0.454
1bwaXV6Gag-Pol polyprotein3.4.23.160.454
1d3pBT3Prothrombin3.4.21.50.454
1dhiMTXDihydrofolate reductase1.5.1.30.454
1draMTXDihydrofolate reductase1.5.1.30.454
1m76CAAHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.454
1qvrANPChaperone protein ClpB/0.454
1zrzBI1Protein kinase C iota type2.7.11.130.454
2anmCDOProthrombin3.4.21.50.454
2cjpVPREpoxide hydrolase/0.454
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.454
2dteNAIGlucose 1-dehydrogenase related protein/0.454
2qi6MZ8Gag-Pol polyprotein/0.454
2vbpVB1Isopenicillin N synthase1.21.3.10.454
2vcj2EQHeat shock protein HSP 90-alpha/0.454
2xfsJ01Uncharacterized protein/0.454
2xgs44PUncharacterized protein/0.454
2y60M8FIsopenicillin N synthase1.21.3.10.454
2zawCAMCamphor 5-monooxygenase1.14.15.10.454
3fl8RARDihydrofolate reductase/0.454
3oxv478Gag-Pol polyprotein3.4.23.160.454
3qwbNDPProbable quinone oxidoreductase1.6.5.50.454
4abkAR6Poly [ADP-ribose] polymerase 142.4.2.300.454
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.454
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.454
4g67SAHUncharacterized ACR, COG1565 superfamily/0.454
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.454
1c3eNHRPhosphoribosylglycinamide formyltransferase/0.453
1c3eGARPhosphoribosylglycinamide formyltransferase/0.453
1f0yCAAHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.453
1fwkADPHomoserine kinase2.7.1.390.453
1hwr216Gag-Pol polyprotein3.4.23.160.453
1mjbACOHistone acetyltransferase ESA1/0.453
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.453
1w4xFADPhenylacetone monooxygenase1.14.13.920.453
1xny191Propionyl-CoA carboxylase complex B subunit/0.453
2bunFADAppA protein/0.453
2hc0AB2Protease/0.453
2qi0MZ3Gag-Pol polyprotein/0.453
2rhrEMOPutative ketoacyl reductase1.3.10.453
2uwd2GGHeat shock protein HSP 90-alpha/0.453
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.453
2zbaZBATrichothecene 3-O-acetyltransferase/0.453
3kb1ADPIron-sulfur cluster carrier protein/0.453
3zbrNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.453
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.453
4elb34RDihydrofolate reductase/0.453
1bdmNAXMalate dehydrogenase/0.452
1cydNDPCarbonyl reductase [NADPH] 21.1.1.1840.452
1lsoNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.452
1p84UQ6Cytochrome b/0.452
1tslA15Thymidylate synthase/0.452
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.452
2givACOHistone acetyltransferase KAT8/0.452
2gtnLIEMitogen-activated protein kinase 14/0.452
2z0x5CAUncharacterized protein/0.452
3a6rFMNFMN-binding protein/0.452
3b2sB2STrichothecene 3-O-acetyltransferase/0.452
3clbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.452
3junAKDPhenazine biosynthesis protein A/B/0.452
3k4cFADPyranose 2-oxidase/0.452
3lpkZ76Beta-secretase 13.4.23.460.452
3sacAF8Protease/0.452
3sw1FMNSensory box protein/0.452
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.452
3vfqAR6Poly [ADP-ribose] polymerase 142.4.2.300.452
3vt8YI3Vitamin D3 receptor/0.452
3zv64HBCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase1.3.1.560.452
4bqg50QHeat shock protein HSP 90-alpha/0.452
4djqM86Pol polyprotein/0.452
4dqb017Gag-Pol polyprotein/0.452
4eph0RKCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.452
1dz6CAMCamphor 5-monooxygenase1.14.15.10.451
1g1aNADdTDP-glucose 4,6-dehydratase/0.451
1g6kNADGlucose 1-dehydrogenase1.1.1.470.451
1guyNADMalate dehydrogenase/0.451
1hfqMOTDihydrofolate reductase1.5.1.30.451
1hviA77Protease/0.451
1hxwRITGag-Pol polyprotein/0.451
1sivPSIGag-Pol polyprotein/0.451
1t3r017Gag-Pol polyprotein3.4.23.160.451
1xdyMTEProtein-methionine-sulfoxide reductase catalytic subunit MsrP/0.451
2a7r5GPGMP reductase 2/0.451
2c29NAPDihydroflavonol 4-reductase/0.451
2cgpCMPcAMP-activated global transcriptional regulator CRP/0.451
2hutSAHDiphthine synthase/0.451
2nnpROCProtease/0.451
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.451
2pfgDDDCarbonyl reductase [NADPH] 11.1.1.1840.451
2qllPLPGlycogen phosphorylase, liver form2.4.1.10.451
2xlrFADPutative flavin-containing monooxygenase/0.451
3cic316Beta-secretase 13.4.23.460.451
3d1z017Gag-Pol polyprotein3.4.23.160.451
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3f1kNAPUncharacterized oxidoreductase YciK10.451
3gi4K60Gag-Pol polyprotein/0.451
3gobHXXDdmC/0.451
3h06VBPGlutamate receptor 2/0.451
3h86AP5Adenylate kinase/0.451
3hllI45Mitogen-activated protein kinase 14/0.451
3lqfNADGalactitol dehydrogenase/0.451
3p7nFMNLight-activated DNA-binding protein EL222/0.451
3rbqGLY_ALA_GLY_ALA_DAOProtein unc-119 homolog A/0.451
3t37FADPyridoxine 4-oxidase/0.451
4anmWULCasein kinase II subunit alpha2.7.11.10.451
4awq592Heat shock protein HSP 90-alpha/0.451
4bqh9VUUDP-N-acetylglucosamine pyrophosphorylase, putative/0.451
4dieC5PCytidylate kinase/0.451
4dpuAGSMevalonate diphosphate decarboxylase/0.451
4dqh017Gag-Pol polyprotein/0.451
4gah0ETAcyl-coenzyme A thioesterase THEM43.1.2.20.451
4jtqNAPAldo-keto reductase family 1 member C2/0.451
4lhtCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.451
4qtuSAM18S rRNA (guanine(1575)-N(7))-methyltransferase/0.451
1dhrNADDihydropteridine reductase1.5.1.340.450
1drhNAPDihydrofolate reductase1.5.1.30.450
1fp2HMOIsoflavone-7-O-methyltransferase 82.1.1.1500.450
1h63FMNPentaerythritol tetranitrate reductase/0.450
1i7gAZ2Peroxisome proliferator-activated receptor alpha/0.450
1j49NADD-lactate dehydrogenase1.1.1.280.450
1jioDEB6-deoxyerythronolide B hydroxylase/0.450
1kszPGSAdenylosuccinate synthetase/0.450
1m78NDPDihydrofolate reductase1.5.1.30.450
1pjcNADAlanine dehydrogenase/0.450
1tcwIM1Gag-Pol polyprotein/0.450
1td2PXLPyridoxal kinase PdxY/0.450
1uyhPU0Heat shock protein HSP 90-alpha/0.450
1xnyBTNPropionyl-CoA carboxylase complex B subunit/0.450
1zemNADXylitol dehydrogenase/0.450
2h9iEADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
2j14GNIPeroxisome proliferator-activated receptor delta/0.450
2psuMUUProtease/0.450
2pym1UNGag-Pol polyprotein3.4.23.160.450
2wi72KLHeat shock protein HSP 90-alpha/0.450
2wsiFADFAD synthase2.7.7.20.450
2y0mACOHistone acetyltransferase KAT8/0.450
2yozOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.450
2z54AB1Gag-Pol polyprotein3.4.23.160.450
2znnS44Peroxisome proliferator-activated receptor alpha/0.450
3a1l2CCCytochrome P450/0.450
3c3eGDP2-phospho-L-lactate transferase/0.450
3d4pNADL-lactate dehydrogenase 11.1.1.270.450
3fwjCAMCamphor 5-monooxygenase1.14.15.10.450
3gviADPMalate dehydrogenase/0.450
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.450
3imgBZ2Pantothenate synthetase6.3.2.10.450
3kf03TLGag-Pol polyprotein/0.450
3lpiZ74Beta-secretase 13.4.23.460.450
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.450
3ndcSAHPrecorrin-4 C(11)-methyltransferase2.1.1.1330.450
3nglNAPBifunctional protein FolD/0.450
3nugNADPyridoxal 4-dehydrogenase1.1.1.1070.450
3o99K13Pol polyprotein/0.450
3pwrROCGag-Pol polyprotein3.4.23.160.450
3r6sCMPCRP-like cAMP-activated global transcriptional regulator/0.450
3sgx0FWDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.450
3uqdATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.450
4bc7FADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.450
4e8yIHAD-beta-D-heptose 7-phosphate kinase/0.450
4ele31IDihydrofolate reductase/0.450
4h9814QUncharacterized protein/0.450
4hdpG52Gag-Pol polyprotein3.4.23.160.450
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.450
4wecNADShort chain dehydrogenase/0.450
4xr9NADCalS8/0.450
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.450
5d3qGDPDynamin-13.6.5.50.450
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.450
1b2lNDCAlcohol dehydrogenase1.1.1.10.449
1ddsMTXDihydrofolate reductase1.5.1.30.449
1jqiFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial/0.449
1mg5NAIAlcohol dehydrogenase1.1.1.10.449
1o9bNAIQuinate/shikimate dehydrogenase/0.449
1qbrXV6Gag-Pol polyprotein3.4.23.160.449
2fdd385Pol protein/0.449
2hmaSAMtRNA-specific 2-thiouridylase MnmA/0.449
2hs1017Protease/0.449
2q5kAB1Protease/0.449
2ym1FADPhenylacetone monooxygenase1.14.13.920.449
3bva2NCGag-Pol polyprotein3.4.23.160.449
3ec0GRLGag-Pol polyprotein3.4.23.470.449
3nbwTR4Ketohexokinase/0.449
3pldF90Endothiapepsin3.4.23.220.449
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.449
4ajbTAPIsocitrate dehydrogenase [NADP]1.1.1.420.449
4c58824Cyclin-G-associated kinase2.7.11.10.449
4du82P0Mevalonate diphosphate decarboxylase/0.449
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
4ew2DXYTrifunctional purine biosynthetic protein adenosine-32.1.2.20.449
4gllNADUDP-glucuronic acid decarboxylase 14.1.1.350.449
4ia7BIVVitamin D3 receptor A/0.449
4l4aCAMCamphor 5-monooxygenase1.14.15.10.449
4mkhAP5Adenylate kinase/0.449
1a8g2Z4Gag-Pol polyprotein3.4.23.160.448
1ez4NADL-lactate dehydrogenase1.1.1.270.448
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.448
1fej2NCGag-Pol polyprotein3.4.23.160.448
1g2aBB2Peptide deformylase3.5.1.880.448
1odw0E8Gag-Pol polyprotein3.4.23.160.448
1p8dCO1Oxysterols receptor LXR-beta/0.448
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.448
2gjlFMNNitronate monooxygenase1.13.12.160.448
2ien017Gag-Pol polyprotein3.4.23.160.448
2vttLZDCyclin-dependent kinase 22.7.11.220.448
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.448
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.448
3aidARQGag-Pol polyprotein3.4.23.160.448
3cd57HI3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.448
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
3el1DR7Gag-Pol polyprotein3.4.23.160.448
3kn03TOBeta-secretase 13.4.23.460.448
3ndwRITGag-Pol polyprotein3.4.23.160.448
3o6o94MHeat shock protein 83/0.448
3o9fK2DGag-Pol polyprotein/0.448
3pbzF02Endothiapepsin3.4.23.220.448
3udq09EBeta-secretase 13.4.23.460.448
3v2uATPProtein GAL3/0.448
4dmmNAP3-oxoacyl-[acyl-carrier-protein] reductase/0.448
4dtiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
4eji0QACytochrome P450 2A131.14.14.10.448
4f650S9Fibroblast growth factor receptor 1/0.448
4g74FADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.448
4mv8ACPBiotin carboxylase6.3.4.140.448
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.448
4o63NADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.448
5hsaFASAlcohol oxidase 11.1.3.130.448
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.447
1kbjFMNCytochrome b2, mitochondrial1.1.2.30.447
1mesDMPGag-Pol polyprotein3.4.23.160.447
1ohr1UNV-1 PROTEASE protein/0.447
1zw9H64ATP-dependent molecular chaperone HSP82/0.447
2daaDCSD-alanine aminotransferase2.6.1.210.447
2dgnDOIAdenylosuccinate synthetase isozyme 1/0.447
2e0aANP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial2.7.11.20.447
2e8uIPEGeranylgeranyl pyrophosphate synthase/0.447
2emrSAHDiphthine synthase/0.447
2ew6Y13Peptide deformylase/0.447
2gblATPCircadian clock protein kinase KaiC2.7.11.10.447
2jlcTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.447
2q3kMUWGag-Pol polyprotein/0.447
2zreAGSProtein RecA/0.447
3busSAHDemethylrebeccamycin-D-glucose O-methyltransferase/0.447
3h3t16HCollagen type IV alpha-3-binding protein/0.447
3hy7097A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.447
3ixp834Ecdysone receptor/0.447
3lshFADPyranose 2-oxidase/0.447
3opxU5PSuppressor of disruption of TFIIS/0.447
3pwm017Gag-Pol polyprotein3.4.23.160.447
3vrwYS5Vitamin D3 receptor/0.447
3w0gW07Vitamin D3 receptor/0.447
4a81DXCMajor pollen allergen Bet v 1-A/0.447
4a87NARMajor pollen allergen Bet v 1-A/0.447
4efuEFUHeat shock protein HSP 90-alpha/0.447
4hdbG52Gag-Pol polyprotein3.4.23.160.447
4hla017Gag-Pol polyprotein3.4.23.160.447
4l4dCAMCamphor 5-monooxygenase1.14.15.10.447
4mokFADPyranose 2-oxidase/0.447
4nbwNADShort-chain dehydrogenase/reductase SDR/0.447
4pneSAHMethyltransferase-like protein/0.447
4q1w017Gag-Pol polyprotein3.4.23.160.447
4q71FADBifunctional protein PutA/0.447
4qi4FADCellobiose dehydrogenase/0.447
4wucANPDNA gyrase subunit B/0.447
5irnADPNucleotide binding oligomerization domain containing 2/0.447
1eh4IC1Casein kinase I homolog 12.7.11.10.446
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.446
1me6IVSPlasmepsin-23.4.23.390.446
1qr6NADNAD-dependent malic enzyme, mitochondrial1.1.1.380.446
1rneC60Renin3.4.23.150.446
1s60COAAminoglycoside N(6')-acetyltransferase type 1/0.446
1tqf32PBeta-secretase 13.4.23.460.446
1y9dTPPPyruvate oxidase1.2.3.30.446
2cvwGDPRibonucleoside-diphosphate reductase large chain 11.17.4.10.446
2g5cNADPrephenate dehydrogenase/0.446
2pciSAHDiphthine synthase/0.446
2q631UNGag-Pol polyprotein3.4.23.160.446
2qo4CHDFatty acid-binding protein 10-A, liver basic/0.446
2w06FRVCyclin-dependent kinase 22.7.11.220.446
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.446
2xjjL81Heat shock protein HSP 90-alpha/0.446
3a3bRBFLumazine protein/0.446
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3ekp478Gag-Pol polyprotein3.4.23.160.446
3eksCY9Actin-5C/0.446
3ekyDR7Gag-Pol polyprotein3.4.23.160.446
3elySAHMethyltransferase/0.446
3h3r14HCollagen type IV alpha-3-binding protein/0.446
3in6FMNUncharacterized protein/0.446
3iqiASN_GLU_ASN_ILECysteine synthase2.5.1.470.446
3oafOAGDihydrofolate reductase1.5.1.30.446
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.446
3pgqGY3Acetyl-CoA carboxylase/0.446
3qbwADPAnhydro-N-acetylmuramic acid kinase/0.446
3sa9A68Protease/0.446
3vvpBNUUncharacterized protein/0.446
3zuyTCHTransporter/0.446
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.446
4bfvZVVPantothenate kinase2.7.1.330.446
4e5yNDPGDP-L-fucose synthase1.1.1.2710.446
4fod0UVALK tyrosine kinase receptor2.7.10.10.446
4g9kFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.446
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.446
4hfp15UProthrombin3.4.21.50.446
4hjfC2EGGDEF family protein/0.446
4i13FOLDihydrofolate reductase1.5.1.30.446
4i6gFADCryptochrome-2/0.446
4kl9NDPDihydrofolate reductase1.5.1.30.446
4njoNADD-3-phosphoglycerate dehydrogenase, putative/0.446
4rlsNAIL-lactate dehydrogenase A chain1.1.1.270.446
5ej9TPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.446
1b6mPI6Gag-Pol polyprotein3.4.23.160.445
1bmdNADMalate dehydrogenase/0.445
1dd6MCIMetallo-beta-lactamase type 2/0.445
1e1mNAPNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.445
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
1g4tFTPThiamine-phosphate synthase/0.445
1i59ADPChemotaxis protein CheA2.7.13.30.445
1i5bANPChemotaxis protein CheA2.7.13.30.445
1i5cADPChemotaxis protein CheA2.7.13.30.445
1izhQ50Protease/0.445
1lrjUD1UDP-glucose 4-epimerase5.1.3.20.445
1menGARTrifunctional purine biosynthetic protein adenosine-32.1.2.20.445
1n77ATPGlutamate--tRNA ligase6.1.1.170.445
1nhtPGSAdenylosuccinate synthetase/0.445
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.445
1zsk421Coagulation factor XI3.4.21.270.445
2avsMK1Gag-Pol polyprotein3.4.23.160.445
2cx8SAHRibosomal RNA small subunit methyltransferase E/0.445
2dsiSAHDiphthine synthase/0.445
2eldSAHDiphthine synthase/0.445
2gzwCMPcAMP-activated global transcriptional regulator CRP/0.445
2huqSAHDiphthine synthase/0.445
2owuSAHDiphthine synthase/0.445
2qd7065Gag-Pol polyprotein3.4.23.160.445
2w3bNDPDihydrofolate reductase1.5.1.30.445
2wi4ZZ4Heat shock protein HSP 90-alpha/0.445
2xfjVG5Beta-secretase 13.4.23.460.445
3cukFADD-amino-acid oxidase1.4.3.30.445
3d1yROCGag-Pol polyprotein3.4.23.160.445
3d7kD7KBenzaldehyde lyase/0.445
3ecg065Gag-Pol polyprotein3.4.23.470.445
3ekt017Gag-Pol polyprotein3.4.23.160.445
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.445
3giyFMN(S)-mandelate dehydrogenase1.1.99.310.445
3i2l2NCProtease/0.445
3mxeK54Gag-Pol polyprotein3.4.23.160.445
3njuANNAcidic phospholipase A2 33.1.1.40.445
3pllF06Endothiapepsin3.4.23.220.445
3qihFG7Gag-Pol polyprotein3.4.23.160.445
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.445
3rvg17PTyrosine-protein kinase JAK2/0.445
3sa8K83Protease/0.445
3sqq99ZCyclin-dependent kinase 22.7.11.220.445
3ua808WGlutamate receptor 2/0.445
3v1yNADGlyceraldehyde-3-phosphate dehydrogenase 1, cytosolic1.2.1.120.445
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.445
4a6nFADTetX family tetracycline inactivation enzyme/0.445
4a83DXCMajor pollen allergen Bet v 1-A/0.445
4ceqQCHIntegrase/0.445
4eu8COASuccinyl-CoA:acetate CoA-transferase/0.445
4fmxCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.445
4h1vGNPDynamin-1-like protein3.6.5.50.445
4jqeANPCasein kinase II subunit alpha2.7.11.10.445
4tuvCPZCytochrome P450 1191.140.445
4yswFADXanthine dehydrogenase/oxidase/0.445
5byuCOAThioesterase/0.445
5jjsSAHGenome polyprotein/0.445
1d7lRFLp-hydroxybenzoate hydroxylase/0.444
1difA85Gag-Pol polyprotein/0.444
1dr3TAPDihydrofolate reductase1.5.1.30.444
1e1kNAPNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.444
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.444
1hrvSDZGenome polyprotein/0.444
1ia4TQ6Dihydrofolate reductase1.5.1.30.444
1k6vXN2Gag-Pol polyprotein3.4.23.160.444
1lonIMOAdenylosuccinate synthetase isozyme 1/0.444
1o2g696Prothrombin3.4.21.50.444
2ath3EAPeroxisome proliferator-activated receptor gamma/0.444
2avm2NCGag-Pol polyprotein3.4.23.160.444
2c2aADPSensor histidine kinase/0.444
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.444
2gqwFADFerredoxin reductase/0.444
2i0zFADNAD(FAD)-utilizing dehydrogenases/0.444
2j5bTYETyrosine--tRNA ligase6.1.1.10.444
2j7pGNPSignal recognition particle protein/0.444
2j7pGNPSignal recognition particle receptor FtsY/0.444
2jkoBIJFocal adhesion kinase 12.7.10.20.444
2qg2A91Heat shock protein HSP 90-alpha/0.444
2rlcCHDCholoylglycine hydrolase3.5.1.240.444
2rqfJH3Hemolymph juvenile hormone binding protein/0.444
2wi1ZZ2Heat shock protein HSP 90-alpha/0.444
2zuiCAMCamphor 5-monooxygenase1.14.15.10.444
3bxrDRRGag-Pol polyprotein3.4.23.160.444
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.444
3mjeNDPAmphB/0.444
3ndxRITGag-Pol polyprotein3.4.23.160.444
3o9hK2EGag-Pol polyprotein/0.444
3pe2E1BCasein kinase II subunit alpha2.7.11.10.444
3r7eX88Cyclin-dependent kinase 22.7.11.220.444
3u8n09SAcetylcholine-binding protein/0.444
3ufnROCGag-Pol polyprotein/0.444
3unk0BYCyclin-dependent kinase 22.7.11.220.444
3uylTYDProbable NDP-rhamnosyltransferase/0.444
3vf9477Tyrosine-protein kinase SYK2.7.10.20.444
3zdgXRXAcetylcholine-binding protein/0.444
3zkbANPDNA gyrase subunit B/0.444
4e93GUITyrosine-protein kinase Fes/Fps2.7.10.20.444
4ewo996Beta-secretase 13.4.23.460.444
4fxy0W2Neurolysin, mitochondrial3.4.24.160.444
4g95OAGDihydrofolate reductase1.5.1.30.444
4j16NADNAD/NADP transhydrogenase alpha subunit 1/0.444
4jin1L7RIO-type serine/threonine-protein kinase Rio12.7.11.10.444
4kba1QMCasein kinase I isoform delta2.7.11.10.444
4ly91YYGlucokinase regulatory protein/0.444
4nh92LCEndoplasmin/0.444
4uirFADOleate hydratase4.2.1.530.444
4y9lFADAcyl-CoA dehydrogenase family member 11/0.444
4yekTHMThymidine phosphorylase/0.444
5bsfNADPyrroline-5-carboxylate reductase/0.444
5c41ACPRibokinase/0.444
5cp4CAMCamphor 5-monooxygenase1.14.15.10.444
1c6zROCProtease/0.443
1d0lBLGMembrane-bound lytic murein transglycosylase B4.2.2.n10.443
1hb1OCVIsopenicillin N synthase1.21.3.10.443
1i6kTYMTryptophan--tRNA ligase6.1.1.20.443
1k2c0Q4Gag-Pol polyprotein3.4.23.160.443
1mvsDTMDihydrofolate reductase1.5.1.30.443
1proA88Gag-Pol polyprotein/0.443
1py5PY1TGF-beta receptor type-12.7.11.300.443
1qltFADVanillyl-alcohol oxidase1.1.3.380.443
1zc3GNPRas-related protein Ral-A/0.443
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.443
2bx8AZQSerum albumin/0.443
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.443
2i7pACOPantothenate kinase 32.7.1.330.443
2po7CHDFerrochelatase, mitochondrial4.99.1.10.443
2q54MU1Protease/0.443
2q59240Peroxisome proliferator-activated receptor gamma/0.443
2qboCAMCamphor 5-monooxygenase1.14.15.10.443
2qnpQN2Gag-Pol polyprotein3.4.23.160.443
2wo7ASVIsopenicillin N synthase1.21.3.10.443
2y9qANPMitogen-activated protein kinase 12.7.11.240.443
2z3uCRRCytochrome P450/0.443
2ze2T27Gag-Pol polyprotein2.7.7.490.443
3a4vNADNDP-sugar epimerase/0.443
3cgdNADCoenzyme A disulfide reductase/0.443
3cnjFADCholesterol oxidase1.1.3.60.443
3eej53RUncharacterized protein/0.443
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.443
3imeBZ2Pantothenate synthetase6.3.2.10.443
3iodA6DPantothenate synthetase6.3.2.10.443
3m2rCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.443
3m2rCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.443
3nu6478Gag-Pol polyprotein3.4.23.160.443
3q43D66M1 family aminopeptidase3.4.110.443
3ql8X01Cyclin-dependent kinase 22.7.11.220.443
3rypCMPcAMP-activated global transcriptional regulator CRP/0.443
3saa77FProtease/0.443
3sp6IL2Peroxisome proliferator-activated receptor alpha/0.443
3zhqTPPMultifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.443
4bqpNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.443
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.443
4eki0QKHistone-lysine N-methyltransferase, H3 lysine-79 specific2.1.1.430.443
4eop1ROCyclin-dependent kinase 22.7.11.220.443
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.443
4giu636Anthranilate phosphoribosyltransferase/0.443
4hdfG52Gag-Pol polyprotein3.4.23.160.443
4i5cC5ITyrosine-protein kinase JAK1/0.443
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4l4xNDPAmphI/0.443
4mr61K0Bromodomain-containing protein 2/0.443
4p9dTMPDeoxycytidylate deaminase/0.443
5fknTDCTetracycline repressor protein class D/0.443
1ai9NDPDihydrofolate reductase1.5.1.30.442
1beuIPLTryptophan synthase alpha chain/0.442
1fff0Q4Gag-Pol polyprotein3.4.23.160.442
1gky5GPGuanylate kinase2.7.4.80.442
1h51FMNPentaerythritol tetranitrate reductase/0.442
1hpxKNIGag-Pol polyprotein/0.442
1ie3NADMalate dehydrogenase/0.442
1k8y13PTryptophan synthase alpha chain/0.442
1ml6GBXGlutathione S-transferase A22.5.1.180.442
1qjfACSIsopenicillin N synthase1.21.3.10.442
1tdrMTXDihydrofolate reductase1.5.1.30.442
1z1hHBBGag-Pol polyprotein3.4.23.160.442
2a5kAZPReplicase polyprotein 1ab3.4.220.442
2beiACODiamine acetyltransferase 22.3.1.570.442
2ou2ACOHistone acetyltransferase KAT5/0.442
2rkfAB1Pol protein/0.442
2vci2GJHeat shock protein HSP 90-alpha/0.442
2vutNADNitrogen metabolite repression protein nmrA/0.442
3a9wNADNDP-sugar epimerase/0.442
3b895GP16S rRNA methylase/0.442
3b9lAZZSerum albumin/0.442
3cib314Beta-secretase 13.4.23.460.442
3djkG55Gag-Pol polyprotein3.4.23.160.442
3eldSFGMethyltransferase/0.442
3em3478Gag-Pol polyprotein3.4.23.160.442
3is2FADVivid PAS protein VVD/0.442
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3jzfJZKBiotin carboxylase6.3.4.140.442
3k0fATPCircadian clock protein kinase KaiC2.7.11.10.442
3p3zP3ZPutative cytochrome P450/0.442
3r7uX96Cyclin-dependent kinase 22.7.11.220.442
3sa5A69Protease/0.442
3sp9IL2Peroxisome proliferator-activated receptor delta/0.442
3tk3CPZCytochrome P450 2B41.14.14.10.442
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.442
4awo99BHeat shock protein HSP 90-alpha/0.442
4g73NAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.442
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
4h4qFADBiphenyl dioxygenase ferredoxin reductase subunit/0.442
4jva1ORcAMP-dependent protein kinase type II-beta regulatory subunit/0.442
4njsG08Protease/0.442
4oqyNDP(S)-imine reductase/0.442
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.442
1cbqRE9Cellular retinoic acid-binding protein 2/0.441
1e7qNAPGDP-L-fucose synthase/0.441
1gj5130Prothrombin3.4.21.50.441
1hiiC20Gag-Pol polyprotein/0.441
1hosPHPGag-Pol polyprotein/0.441
1i6xCMPcAMP-activated global transcriptional regulator CRP/0.441
1kquBR4Phospholipase A2, membrane associated/0.441
1nvtNAPShikimate dehydrogenase (NADP(+))/0.441
1svmATPLarge T antigen3.6.40.441
1zz2B11Mitogen-activated protein kinase 14/0.441
2cchATPCyclin-dependent kinase 22.7.11.220.441
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.441
2cy0NAPShikimate dehydrogenase (NADP(+))/0.441
2dshSAHDiphthine synthase/0.441
2favAPRNonstructural polyprotein pp1a/0.441
2fleAIProtease/0.441
2ifaFMNUncharacterized protein/0.441
2jn3JN3Fatty acid-binding protein, liver/0.441
2q2vNADBeta-D-hydroxybutyrate dehydrogenase/0.441
2uxoTACHTH-type transcriptional regulator TtgR/0.441
2vwhNAPGlucose 1-dehydrogenase/0.441
2w9hTOPDihydrofolate reductase1.5.1.30.441
2znpK55Peroxisome proliferator-activated receptor delta/0.441
3cgfJNFMitogen-activated protein kinase 102.7.11.240.441
3d574HYThyroid hormone receptor beta/0.441
3dafFEG5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.441
3eel53TUncharacterized protein/0.441
3eyaTDPPyruvate dehydrogenase [ubiquinone]1.2.5.10.441
3ha3SAHHydroxymycolate synthase MmaA42.1.10.441
3jvwDMPGag-Pol polyprotein3.4.23.160.441
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3mknDNBPyrimidine-specific ribonucleoside hydrolase RihB/0.441
3mp3HGGHydroxymethylglutaryl-CoA lyase, mitochondrial4.1.3.40.441
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.441
3oxw017Gag-Pol polyprotein3.4.23.160.441
3pgpACOUncharacterized protein/0.441
3qvpFADGlucose oxidase1.1.3.40.441
3rasNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.441
3slkNDPPolyketide synthase extender module 2/0.441
3toxNAPPutative oxidoreductase/0.441
3vaqADNPutative adenosine kinase/0.441
3wv9FEGHmd co-occurring protein HcgE/0.441
3zvvXAZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4djr0KJPol polyprotein/0.441
4eu5COASuccinyl-CoA:acetate CoA-transferase/0.441
4j54G52Gag-Pol polyprotein3.4.23.160.441
4m5pFMNNADPH dehydrogenase/0.441
4ntcFADThioredoxin reductase gliT/0.441
4rf2NAPNADPH dependent R-specific alcohol dehydrogenase/0.441
4x7zZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.441
1fvpFMANon-fluorescent flavoprotein/0.440
1jkx138Phosphoribosylglycinamide formyltransferase/0.440
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.440
1llzFMNFerredoxin-dependent glutamate synthase 21.4.7.10.440
1lquNDPNADPH-ferredoxin reductase FprA1.18.1.20.440
1mjaCOAHistone acetyltransferase ESA1/0.440
1ni4TPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.440
1ni4TPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.440
1pqc444Oxysterols receptor LXR-beta/0.440
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.440
1rq1FADEndoplasmic oxidoreductin-11.8.40.440
1rrmAPRLactaldehyde reductase1.1.1.770.440
1rx1NAPDihydrofolate reductase1.5.1.30.440
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.440
1tl7FOKAdenylate cyclase type 2/0.440
1tl7FOKAdenylate cyclase type 5/0.440
1udaUFGUDP-glucose 4-epimerase5.1.3.20.440
1uy8PU5Heat shock protein HSP 90-alpha/0.440
1wzeNADMalate dehydrogenase/0.440
1x2hLPALipoate-protein ligase A6.3.1.200.440
1yc443PHeat shock protein HSP 90-alpha/0.440
1zsr0ZTGag-Pol polyprotein3.4.23.160.440
2ab8ACPAdenosine kinase2.7.1.200.440
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
2fhnBNIAvidin-related protein 4/5/0.440
2fj1CTCTetracycline repressor protein class D/0.440
2fk8SAMHydroxymycolate synthase MmaA42.1.10.440
2itnANPEpidermal growth factor receptor2.7.10.10.440
2pg0FADAcyl-CoA dehydrogenase/0.440
2qhyMZ1Gag-Pol polyprotein/0.440
2webPP4Penicillopepsin-13.4.23.200.440
2wotZZGTGF-beta receptor type-12.7.11.300.440
2yk2YJWHeat shock protein HSP 90-alpha/0.440
2yk2YJXHeat shock protein HSP 90-alpha/0.440
3ac1KZITyrosine-protein kinase Lck2.7.10.20.440
3eljGS7Mitogen-activated protein kinase 82.7.11.240.440
3fln3FNMitogen-activated protein kinase 14/0.440
3hk1B64Fatty acid-binding protein, adipocyte/0.440
3iaeD7KBenzaldehyde lyase/0.440
3kfr3TLGag-Pol polyprotein/0.440
3mteSAM16S rRNA (adenine(1408)-N(1))-methyltransferase2.1.1.1800.440
3p62FMNPentaerythritol tetranitrate reductase/0.440
3pdqKC6Lysine-specific demethylase 4A1.14.110.440
3pxyJWSCyclin-dependent kinase 22.7.11.220.440
3qihNI7Gag-Pol polyprotein3.4.23.160.440
3qqkX02Cyclin-dependent kinase 22.7.11.220.440
3r9uFADThioredoxin reductase/0.440
3t7x4SHEndothiapepsin3.4.23.220.440
3tozNADShikimate dehydrogenase (NADP(+))/0.440
4a32MYAGlycylpeptide N-tetradecanoyltransferase/0.440
4aacAAVMitogen-activated protein kinase 14/0.440
4df2FMNNADPH dehydrogenase/0.440
4e4m0NHTyrosine-protein kinase JAK2/0.440
4g1z0VPVitamin D3 receptor A/0.440
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.440
4hmsFMNPhenazine biosynthesis protein PhzG1.40.440
4iv6FDAIsovaleryl-CoA dehydrogenase/0.440
4l4cCAMCamphor 5-monooxygenase1.14.15.10.440
4l7f1V5Mitogen-activated protein kinase 82.7.11.240.440
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.440
4nd2A3DLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.440
4tmcFMNOld yellow enzyme/0.440
4ux9ANPMitogen-activated protein kinase 82.7.11.240.440
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.440
4xybNDPFormate dehydrogenase/0.440
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.440
5d3fFSC14-3-3 protein zeta/delta/0.440
5jtbZMAAdenosine receptor A2a/0.440