sc-PDB

List of CHEMBLId :

This value allows a number of roughly comparable measures of half-maximal response concentration/potency/affinity to be compared on a negative logarithmic scale (e.g., an IC50 measurement of 1nM would have a pChEMBL value of 9).

Uniprot Annotation

Name:	Focal adhesion kinase 1
ID:	FAK1_CHICK
AC:	Q00944
Organism:	Gallus gallus
Reign:	Eukaryota
TaxID:	9031
EC Number:	2.7.10.2

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Chains:

Chain Name:	Percentage of Residues within binding site
A	100 %

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Ligand binding site composition:

B-Factor:	28.099
Number of residues:	32
Including
Standard Amino Acids:	32
Non Standard Amino Acids:	0
Water Molecules:	0
Cofactors:
Metals:

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Cavity properties

Ligandability	Volume (Å3)
1.299	472.500

% Hydrophobic	% Polar
60.00	40.00
According to VolSite

HET Code:	BIJ
Formula:	C25H31ClN7O2
Molecular weight:	497.012 g/mol
DrugBank ID:	-
Buried Surface Area:	57.29 %
Polar Surface area:	89.55 Å2

Number of
H-Bond Acceptors:	4
H-Bond Donors:	4
Rings:	5
Aromatic rings:	2
Anionic atoms:	0
Cationic atoms:	3
Rule of Five Violation:	0
Rotatable Bonds:	5

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Mass center Coordinates

X	Y	Z
28.8043	23.7359	35.7015

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