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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4hzt0ZABeta-secretase 13.4.23.46

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
4hzt0ZABeta-secretase 13.4.23.461.000
4i111CHBeta-secretase 13.4.23.460.623
4i0f1BFBeta-secretase 13.4.23.460.553
4i0z1BBBeta-secretase 13.4.23.460.548
3bugAEHBeta-secretase 13.4.23.460.541
1e79ATPATP synthase subunit alpha, mitochondrial/0.535
1e79ATPATP synthase subunit beta, mitochondrial3.6.3.140.535
4ke11R6Beta-secretase 13.4.23.460.521
4b0532DBeta-secretase 13.4.23.460.512
4i121BCBeta-secretase 13.4.23.460.511
1j78VDYVitamin D-binding protein/0.509
2nr4FMNConserved protein/0.506
3bgsDIHPurine nucleoside phosphorylase2.4.2.10.504
1dduDDUThymidylate synthase/0.503
4dju0KKBeta-secretase 13.4.23.460.502
1dduCB3Thymidylate synthase/0.501
1e1qANPATP synthase subunit alpha, mitochondrial/0.501
1e1qANPATP synthase subunit beta, mitochondrial3.6.3.140.501
1j9zFADNADPH--cytochrome P450 reductase/0.501
2poqISDTrans-1,2-dihydrobenzene-1,2-diol dehydrogenase1.3.1.200.500
3fr5I4AFatty acid-binding protein, adipocyte/0.500
3hl4CDCCholine-phosphate cytidylyltransferase A/0.498
2rlcCHDCholoylglycine hydrolase3.5.1.240.497
3wqmB29Diterpene synthase3.1.7.80.497
4kbyC2EStimulator of interferon genes protein/0.497
2g1n1IGRenin3.4.23.150.496
5dv2C5PCCR4-NOT transcription complex subunit 6-like3.1.13.40.496
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.495
3qi1C6ABeta-secretase 13.4.23.460.495
4b64NAPL-ornithine N(5)-monooxygenase/0.495
4j1c1HOBeta-secretase 13.4.23.460.495
2hxdDUPdCTP deaminase, dUMP-forming3.5.4.300.494
2e07SAHDiphthine synthase/0.493
2e0nSAHPrecorrin-2 C20-methyltransferase/0.493
3swcSAHHistone-lysine N-methyltransferase EHMT1/0.493
4j0v1H7Beta-secretase 13.4.23.460.493
2rkuR78Serine/threonine-protein kinase PLK12.7.11.210.492
1cnfFADNitrate reductase [NADH]1.7.1.10.491
4b4vL34Bifunctional protein FolD/0.490
1ikiREYD-alanyl-D-alanine carboxypeptidase3.4.16.40.489
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.489
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.489
1pf7IMHPurine nucleoside phosphorylase2.4.2.10.488
3bgxTMPThymidylate synthase/0.488
3gf4U5PUDP-galactopyranose mutase5.4.99.90.488
4ise1FWGlucokinase2.7.1.20.488
4j0t6T9Beta-secretase 13.4.23.460.488
5cc9DDFDihydrofolate reductase1.5.1.30.488
3vw7VPXProteinase-activated receptor 1/0.488
1vceSAHDiphthine synthase/0.487
2a2cADPN-acetylgalactosamine kinase2.7.1.1570.487
2yoj8Y6Genome polyprotein2.7.7.480.487
3l5dBDVBeta-secretase 13.4.23.460.487
3q9bB3NAcetylpolyamine amidohydrolase/0.487
3ufl508Beta-secretase 13.4.23.460.487
4i0h1BLBeta-secretase 13.4.23.460.487
1mu6CDAProthrombin3.4.21.50.486
1rzuADPGlycogen synthase 12.4.1.210.486
2dxwSAHDiphthine synthase/0.486
4j1k1HGBeta-secretase 13.4.23.460.486
1f4fTP3Thymidylate synthase/0.485
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.485
2j08IRFDeoxyribodipyrimidine photo-lyase4.1.99.30.485
2rqfJH3Hemolymph juvenile hormone binding protein/0.485
2va7C27Beta-secretase 13.4.23.460.485
2zff53UProthrombin3.4.21.50.485
4ax9N5NProthrombin3.4.21.50.485
4b4w9L9Bifunctional protein FolD/0.485
4j1f1HLBeta-secretase 13.4.23.460.485
4lc71WPBeta-secretase 13.4.23.460.485
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.484
2bb3SAHCobalamin biosynthesis precorrin-6Y methylase (CbiE)/0.484
2emrSAHDiphthine synthase/0.484
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.484
4eb4UMPThymidylate synthase2.1.1.450.484
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.483
1gky5GPGuanylate kinase2.7.4.80.482
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.482
2vyqFADFerredoxin--NADP reductase1.18.1.20.482
3k5fAYHBeta-secretase 13.4.23.460.482
3zhoFMNNAD(P)H dehydrogenase (quinone)/0.482
2ejzSAHDiphthine synthase/0.481
2ohjFMNType A flavoprotein FprA10.481
4b66NAPL-ornithine N(5)-monooxygenase/0.481
1an5CB3Thymidylate synthase/0.480
2y1tDUDSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.480
3bgxMEFThymidylate synthase/0.480
3iktNADRedox-sensing transcriptional repressor Rex/0.480
4fm80UQBeta-secretase 13.4.23.460.480
1gj5130Prothrombin3.4.21.50.479
1nm6L86Prothrombin3.4.21.50.479
1touB1VFatty acid-binding protein, adipocyte/0.479
2iu8UD1UDP-3-O-acylglucosamine N-acyltransferase2.3.10.479
2xjc5GPCytosolic purine 5'-nucleotidase3.1.3.50.479
4lxm1YUBeta-secretase 13.4.23.460.479
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.479
3t7qRB4Endothiapepsin3.4.23.220.478
4bekXK0Beta-secretase 13.4.23.460.478
2a5kAZPReplicase polyprotein 1ab3.4.220.477
2e1mFADL-glutamate oxidase/0.477
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.477
2i65NADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.477
2j09FMNDeoxyribodipyrimidine photo-lyase4.1.99.30.477
3f03FMNPentaerythritol tetranitrate reductase/0.477
3kmxG00Beta-secretase 13.4.23.460.477
4i0j842Beta-secretase 13.4.23.460.477
1z71L17Prothrombin3.4.21.50.476
2el0SAHDiphthine synthase/0.476
2pcaSAHDiphthine synthase/0.476
2pncCLUPrimary amine oxidase, liver isozyme/0.476
4j521J3Serine/threonine-protein kinase PLK12.7.11.210.476
1culFOKAdenylate cyclase type 2/0.475
1culFOKAdenylate cyclase type 5/0.475
1dirNADDihydropteridine reductase1.5.1.340.475
1pwyAC2Purine nucleoside phosphorylase2.4.2.10.475
1t4u81AProthrombin3.4.21.50.475
1w0kADPATP synthase subunit alpha, mitochondrial/0.475
1w0kADPATP synthase subunit beta, mitochondrial3.6.3.140.475
1xm1GAHProthrombin3.4.21.50.475
2zgb21UProthrombin3.4.21.50.475
1t7o152Carnitine O-acetyltransferase2.3.1.70.474
1txtCAAHMG-CoA synthase/0.474
2vj6VG5Beta-secretase 13.4.23.460.474
3uph0C1Genome polyprotein2.7.7.480.474
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.474
1b2lNDCAlcohol dehydrogenase1.1.1.10.473
1cs4FOKAdenylate cyclase type 2/0.473
1cs4FOKAdenylate cyclase type 5/0.473
1rkwPNTHTH-type transcriptional regulator QacR/0.473
1yw7A41Methionine aminopeptidase 2/0.473
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.473
2emuSAHDiphthine synthase/0.473
2g1o2IGRenin3.4.23.150.473
2zdv37UProthrombin3.4.21.50.473
2zvbSAHPrecorrin-3 C17-methyltransferase/0.473
3fhxPXLPyridoxal kinase2.7.1.350.473
3fsjD7KBenzoylformate decarboxylase4.1.1.70.473
3qj0QI3Botulinum neurotoxin type A3.4.24.690.473
4i6h1C8Serine/threonine-protein kinase PLK22.7.11.210.473
1n8wCOAMalate synthase G/0.472
1rctNOSPurine nucleoside phosphorylase2.4.2.10.472
2gv8NDPThiol-specific monooxygenase1.14.130.472
2rfiSAHHistone-lysine N-methyltransferase EHMT1/0.472
2vetUMPThymidylate synthase/0.472
2yac937Serine/threonine-protein kinase PLK12.7.11.210.472
2z6rSAHDiphthine synthase/0.472
3qgi33FGenome polyprotein2.7.7.480.472
1rz1NADPhenol 2-hydroxylase component B/0.471
1toiHCIAspartate aminotransferase2.6.1.10.471
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.471
2nnqT4BFatty acid-binding protein, adipocyte/0.471
3dv5BAVBeta-secretase 13.4.23.460.471
3hkuTORCarbonic anhydrase 24.2.1.10.471
3zlq6T9Beta-secretase 23.4.23.450.471
4lrrCF9Thymidylate synthase/0.471
1bwkFMNNADPH dehydrogenase 11.6.99.10.470
1fwmCB3Thymidylate synthase/0.470
1iayAVG1-aminocyclopropane-1-carboxylate synthase 24.4.1.140.470
1lvu9PPPurine nucleoside phosphorylase2.4.2.10.470
1ri1GTGmRNA cap guanine-N7 methyltransferase2.1.1.560.470
1wm1PTBProline iminopeptidase3.4.11.50.470
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.470
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.470
3eheNADUDP-glucose 4-epimerase (GalE-1)/0.470
3fr4F8AFatty acid-binding protein, adipocyte/0.470
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.470
3jyqNADQuinate/shikimate dehydrogenase (NAD(+))/0.470
5jj0SAMHistone-lysine N-methyltransferase EHMT2/0.470
1akcPPEAspartate aminotransferase, mitochondrial2.6.1.10.469
1d6w00RProthrombin3.4.21.50.469
1w51L01Beta-secretase 13.4.23.460.469
2rd2QSIGlutamine--tRNA ligase6.1.1.180.469
2rehFADNitroalkane oxidase1.7.3.10.469
3exo5MSBeta-secretase 13.4.23.460.469
3mj4URMUDP-galactopyranose mutase/0.469
3phjDHKShikimate dehydrogenase (NADP(+))/0.469
4bftZVTPantothenate kinase2.7.1.330.469
1tojHCIAspartate aminotransferase2.6.1.10.468
1v2hGUNPurine nucleoside phosphorylase2.4.2.10.468
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.468
2v3oI26Prothrombin3.4.21.50.468
3c1kT15Prothrombin3.4.21.50.468
3hk1B64Fatty acid-binding protein, adipocyte/0.468
3vydVYDRenin3.4.23.150.468
4bb3KKAIsopenicillin N synthase1.21.3.10.468
4j1e1HMBeta-secretase 13.4.23.460.468
5choFADFlavin reductase/0.468
1d3dBZTProthrombin3.4.21.50.467
1jomFFODihydrofolate reductase1.5.1.30.467
2cekN8TAcetylcholinesterase3.1.1.70.467
2e8qSAHDiphthine synthase/0.467
2p9dSAHDiphthine synthase/0.467
2vf0F89Thymidylate synthase/0.467
2zc922UProthrombin3.4.21.50.467
3uzzASD3-oxo-5-beta-steroid 4-dehydrogenase/0.467
3zmg6Z0Beta-secretase 13.4.23.460.467
4dq1UMPThymidylate synthase/0.467
4egnTWOCytochrome P450/0.467
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.467
4j0y1H6Beta-secretase 13.4.23.460.467
2ed5SAHDiphthine synthase/0.466
2fhjH4ZFormylmethanofuran--tetrahydromethanopterin formyltransferase2.3.1.1010.466
2p5uNADUDP-glucose 4-epimerase/0.466
3biu10UProthrombin3.4.21.50.466
3d4bDZDNAD-dependent protein deacetylase/0.466
3n4l842Beta-secretase 13.4.23.460.466
3vyeVYERenin3.4.23.150.466
4mr92BXGamma-aminobutyric acid type B receptor subunit 1/0.466
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.466
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.466
4xq6FMNDihydroorotate dehydrogenase (quinone)/0.466
1f20FADNitric oxide synthase, brain1.14.13.390.465
1foaUD1Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase2.4.1.1010.465
1lv89PPPurine nucleoside phosphorylase2.4.2.10.465
1o9bNAIQuinate/shikimate dehydrogenase/0.465
1x2bSTXProline iminopeptidase3.4.11.50.465
1yryMSGPurine nucleoside phosphorylase2.4.2.10.465
2a2xNA9Prothrombin3.4.21.50.465
2jh0701Prothrombin3.4.21.50.465
2zf051UProthrombin3.4.21.50.465
2zhe13UProthrombin3.4.21.50.465
3a3yOBNSodium/potassium-transporting ATPase subunit alpha/0.465
3hnaSAHHistone-lysine N-methyltransferase EHMT1/0.465
3kmyD8YBeta-secretase 13.4.23.460.465
3t7sSAMUncharacterized protein/0.465
3zv7NHGAcetylcholinesterase3.1.1.70.465
4l7j1W2Beta-secretase 13.4.23.460.465
4o9cCOAAcetyl-CoA acetyltransferase2.3.1.90.465
4xymCOAAcyl-CoA synthetase (NDP forming)/0.465
1p0pBCHCholinesterase3.1.1.80.464
1tduDURThymidylate synthase/0.464
1yqsBSAD-alanyl-D-alanine carboxypeptidase3.4.16.40.464
2jgsBTNAvidin/0.464
2xvhFADPutative flavin-containing monooxygenase/0.464
3bhlTHGThymidylate synthase/0.464
3h3qH13Collagen type IV alpha-3-binding protein/0.464
3qwc98PProthrombin3.4.21.50.464
3zhqTPPMultifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.464
4isf1FXGlucokinase2.7.1.20.464
4qaiFMNNADPH dehydrogenase/0.464
4s1iPLPPyridoxal kinase, putative/0.464
1ae8AZLProthrombin3.4.21.50.463
1ee9NADMethylenetetrahydrofolate dehydrogenase [NAD(+)]1.5.1.150.463
1h22E10Acetylcholinesterase3.1.1.70.463
1vjtNADAlpha-glucosidase, putative/0.463
1zdwFLVPrenyltransferase/0.463
1zgv501Prothrombin3.4.21.50.463
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.463
2ek4SAHDiphthine synthase/0.463
2ohr8IPBeta-secretase 13.4.23.460.463
2owfSAHDiphthine synthase/0.463
2zsiGA4Gibberellin receptor GID1A30.463
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.463
3akzGSUGlutamate--tRNA ligase 2/0.463
3c27DKKProthrombin3.4.21.50.463
3e78TPPHigh affinity transport system protein p37/0.463
3vf30GSBeta-secretase 13.4.23.460.463
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.463
4dvi2IWTankyrase-12.4.2.300.463
4j0p1H8Beta-secretase 13.4.23.460.463
4lxb7R9Prothrombin3.4.21.50.463
1afeALZProthrombin3.4.21.50.462
1d4pBPPProthrombin3.4.21.50.462
1lc3NADBiliverdin reductase A1.3.1.240.462
1ta6177Prothrombin3.4.21.50.462
1v3q2DIPurine nucleoside phosphorylase2.4.2.10.462
1ypjUIBProthrombin3.4.21.50.462
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.462
2o8jSAHHistone-lysine N-methyltransferase EHMT2/0.462
2pksG44Prothrombin3.4.21.50.462
2zrvFNRIsopentenyl-diphosphate delta-isomerase/0.462
3fznD7KBenzoylformate decarboxylase4.1.1.70.462
3keqNADRedox-sensing transcriptional repressor Rex/0.462
3ntrNADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.462
3p8iFMNPentaerythritol tetranitrate reductase/0.462
4acxS8ZBeta-secretase 13.4.23.460.462
4imfSI3N-acetylneuraminate lyase/0.462
4p9dTMPDeoxycytidylate deaminase/0.462
4u163C0Muscarinic acetylcholine receptor M3/0.462
1cjuFOKAdenylate cyclase type 2/0.461
1cjuFOKAdenylate cyclase type 5/0.461
1fkhSBXPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.461
1fw0KAIGlutamate receptor 2/0.461
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.461
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.461
2wzySQXSoluble acetylcholine receptor/0.461
3c0zSHHHistone deacetylase 73.5.1.980.461
3e51N35Genome polyprotein2.7.7.480.461
3ibqATPPyridoxal kinase/0.461
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.461
3pn1IVHDNA ligase/0.461
3zovWZVBeta-secretase 13.4.23.460.461
4bfvZVVPantothenate kinase2.7.1.330.461
4uugPXGBranched-chain amino acid aminotransferase, putative/0.461
1gj4132Prothrombin3.4.21.50.460
1po7TZDBenzoylformate decarboxylase4.1.1.70.460
1rftPXMPyridoxal kinase2.7.1.350.460
1sezOMNProtoporphyrinogen oxidase, mitochondrial1.3.3.40.460
1umaIN2Prothrombin3.4.21.50.460
2ed3SAHDiphthine synthase/0.460
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.460
2uuk897Prothrombin3.4.21.50.460
2zjnF1NBeta-secretase 13.4.23.460.460
3bj8COADiamine acetyltransferase 1/0.460
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.460
3er93ATPoly(A) polymerase catalytic subunit2.7.7.190.460
3fhxPLPPyridoxal kinase2.7.1.350.460
3o5rFK5Peptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.460
3p62FMNPentaerythritol tetranitrate reductase/0.460
3rq6APRADP-dependent (S)-NAD(P)H-hydrate dehydratase/0.460
4b1c1B1Beta-secretase 13.4.23.460.460
4b68NAPL-ornithine N(5)-monooxygenase/0.460
4b78KGGBeta-secretase 13.4.23.460.460
4bfwZVWPantothenate kinase2.7.1.330.460
4eu4COASuccinyl-CoA:acetate CoA-transferase/0.460
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.460
5esoTDP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.460
1a9cGTPGTP cyclohydrolase 13.5.4.160.459
1e63FADFerredoxin--NADP reductase1.18.1.20.459
1h8hATPATP synthase subunit alpha, mitochondrial/0.459
1h8hATPATP synthase subunit beta, mitochondrial3.6.3.140.459
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.459
1zxnADPDNA topoisomerase 2-alpha5.99.1.30.459
2dv3SAHDiphthine synthase/0.459
2dv4SAHDiphthine synthase/0.459
2hizLIJBeta-secretase 13.4.23.460.459
2v3hI25Prothrombin3.4.21.50.459
2zryFNRIsopentenyl-diphosphate delta-isomerase/0.459
3a0tADPSensor histidine kinase/0.459
3gluLYS_VAL_METNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.459
3p0fBAUUridine phosphorylase 22.4.2.30.459
3stdMQ0Scytalone dehydratase4.2.1.940.459
3vjlW94Dipeptidyl peptidase 4/0.459
3zknWZVBeta-secretase 23.4.23.450.459
4a3uFMNNADH:flavin oxidoreductase/NADH oxidase/0.459
4df2FMNNADPH dehydrogenase/0.459
4e2xTYDMethyltransferase/0.459
4f3gKAIGlutamate receptor 3/0.459
4m52M52Dihydrolipoyl dehydrogenase1.8.1.40.459
1gtrATPGlutamine--tRNA ligase6.1.1.180.458
1h51FMNPentaerythritol tetranitrate reductase/0.458
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.458
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.458
1w34FADFerredoxin--NADP reductase1.18.1.20.458
2pchSAHDiphthine synthase/0.458
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.458
2va6H24Beta-secretase 13.4.23.460.458
2xukTZ5Acetylcholinesterase3.1.1.70.458
2zhw12UProthrombin3.4.21.50.458
3fp0FP015-O-acetyltransferase/0.458
4cloNAPPteridine reductase/0.458
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.458
4lsjLSJGlucocorticoid receptor/0.458
4n3l2FNProthrombin3.4.21.50.458
4q71FADBifunctional protein PutA/0.458
5f59SAHHistone-lysine N-methyltransferase 2C2.1.1.430.458
1a26CNAPoly [ADP-ribose] polymerase 12.4.2.300.457
1o0d163Prothrombin3.4.21.50.457
1t2cNAIL-lactate dehydrogenase1.1.1.270.457
2r2nKYNKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.457
2xupTZ5Acetylcholinesterase3.1.1.70.457
2y60M8FIsopenicillin N synthase1.21.3.10.457
2zgx29UProthrombin3.4.21.50.457
3bxoUPPdTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose/0.457
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
3i6iNDPPutative leucoanthocyanidin reductase 1/0.457
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
3mytEQUSteroid Delta-isomerase5.3.3.10.457
3ske054Genome polyprotein2.7.7.480.457
3vf60H6Glucokinase2.7.1.20.457
3wv9FEGHmd co-occurring protein HcgE/0.457
4e2bFMNDehydrogenase/0.457
4j0z1H5Beta-secretase 13.4.23.460.457
4jxxATPGlutamine--tRNA ligase6.1.1.180.457
4knzCB3Thymidylate synthase/0.457
4o7uTHFThymidylate synthase/0.457
1og4NAIT-cell ecto-ADP-ribosyltransferase 2/0.456
1t4v14AProthrombin3.4.21.50.456
1umcTDP2-oxoisovalerate dehydrogenase subunit alpha1.2.4.40.456
1umcTDP2-oxoisovalerate dehydrogenase subunit beta1.2.4.40.456
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.456
2gtbAZPOrf1ab polyprotein/0.456
2owuSAHDiphthine synthase/0.456
2v13C40Renin3.4.23.150.456
3co93MSGenome polyprotein2.7.7.480.456
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.456
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.456
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.456
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.456
4b67NAPL-ornithine N(5)-monooxygenase/0.456
4bfuZVUPantothenate kinase2.7.1.330.456
4c49HCYCorticosteroid-binding globulin/0.456
4fuiUI3Urokinase-type plasminogen activator3.4.21.730.456
4ho6UTPGlucose-1-phosphate thymidylyltransferase/0.456
4ih71ERGenome polyprotein2.7.7.480.456
4q0kGA3Phytohormone-binding protein/0.456
1euyQSIGlutamine--tRNA ligase6.1.1.180.455
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.455
1kt8ILPBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.455
1pr4MTPPurine nucleoside phosphorylase DeoD-type/0.455
1q45FMN12-oxophytodienoate reductase 31.3.1.420.455
1qtiGNTAcetylcholinesterase3.1.1.70.455
1zgbA1EAcetylcholinesterase3.1.1.70.455
2a2dANPN-acetylgalactosamine kinase2.7.1.1570.455
2e4nSAHDiphthine synthase/0.455
2egbSAHDiphthine synthase/0.455
2eldSAHDiphthine synthase/0.455
2ga2A19Methionine aminopeptidase 2/0.455
2i4qUA4Renin3.4.23.150.455
2q153MRBeta-secretase 13.4.23.460.455
2zrxFMNIsopentenyl-diphosphate delta-isomerase/0.455
3c15FOKAdenylate cyclase type 2/0.455
3c15FOKAdenylate cyclase type 5/0.455
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.455
3h5sH5SGenome polyprotein2.7.7.480.455
3sqwANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.455
4ewo996Beta-secretase 13.4.23.460.455
4frkDWDBeta-secretase 13.4.23.460.455
4i1c1BEBeta-secretase 13.4.23.460.455
4l7g1W0Beta-secretase 13.4.23.460.455
4stdBFSScytalone dehydratase4.2.1.940.455
5stdUNNScytalone dehydratase4.2.1.940.455
1ex75GPGuanylate kinase2.7.4.80.454
1g6kNADGlucose 1-dehydrogenase1.1.1.470.454
1o2g696Prothrombin3.4.21.50.454
1qx4FADNADH-cytochrome b5 reductase 31.6.2.20.454
1ypmRA4Prothrombin3.4.21.50.454
2abjCBCBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.454
2ek7SAHDiphthine synthase/0.454
2g1y5IGRenin3.4.23.150.454
2r97FMNNAD(P)H dehydrogenase (quinone)/0.454
2vq7FADPutative flavin-containing monooxygenase/0.454
3mo0SAHHistone-lysine N-methyltransferase EHMT1/0.454
3qvrFADGlucose oxidase1.1.3.40.454
3w6hAZMCarbonic anhydrase 14.2.1.10.454
4drm0MCPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.454
4fa30SLAldo-keto reductase family 1 member C3/0.454
4fhd0TTSpore photoproduct lyase/0.454
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.454
4isg1FYGlucokinase2.7.1.20.454
4uy6SAHHistidine N-alpha-methyltransferase/0.454
5fi8ORODihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.454
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
1cjkFOKAdenylate cyclase type 2/0.453
1cjkFOKAdenylate cyclase type 5/0.453
1h60STRPentaerythritol tetranitrate reductase/0.453
1icsFMN12-oxophytodienoate reductase 11.3.1.420.453
1jf0CZHObelin/0.453
1votHUPAcetylcholinesterase3.1.1.70.453
1x2eATXProline iminopeptidase3.4.11.50.453
2e17SAHDiphthine synthase/0.453
2egsSAHDiphthine synthase/0.453
2nvdITBAldose reductase1.1.1.210.453
2zfp19UProthrombin3.4.21.50.453
3nmpPYVAbscisic acid receptor PYL2/0.453
3ojxFADNADPH--cytochrome P450 reductase/0.453
3rtnRTNBeta-secretase 13.4.23.460.453
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.453
3w0tHPULactoylglutathione lyase4.4.1.50.453
4bewACPSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.453
4f6w0SSCyclin-dependent kinase 82.7.11.220.453
4gg1TZDBenzoylformate decarboxylase4.1.1.70.453
4k8s1QTBeta-secretase 13.4.23.460.453
5dp2NAPCurF/0.453
5kgpACOPredicted acetyltransferase/0.453
1akbPPDAspartate aminotransferase, mitochondrial2.6.1.10.452
1b8oIMHPurine nucleoside phosphorylase2.4.2.10.452
1bcuPRLProthrombin3.4.21.50.452
1dr4HBIDihydrofolate reductase1.5.1.30.452
1dtnAPGMandelate racemase/0.452
1h50FMNPentaerythritol tetranitrate reductase/0.452
1kw6BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.452
1mzcBNEProtein farnesyltransferase subunit beta2.5.1.580.452
1npdNADQuinate/shikimate dehydrogenase/0.452
1nqw5YL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.452
1oyaFMNNADPH dehydrogenase 11.6.99.10.452
1qoqIGPTryptophan synthase alpha chain/0.452
1umkFADNADH-cytochrome b5 reductase 31.6.2.20.452
2p6iSAHDiphthine synthase/0.452
2pckSAHDiphthine synthase/0.452
2xviFADPutative flavin-containing monooxygenase/0.452
2znk31UProthrombin3.4.21.50.452
3c16FOKAdenylate cyclase type 2/0.452
3c16FOKAdenylate cyclase type 5/0.452
3eksCY9Actin-5C/0.452
3k8q22APurine nucleoside phosphorylase2.4.2.10.452
3n0hTOPDihydrofolate reductase1.5.1.30.452
3nn6HNK6-hydroxy-L-nicotine oxidase/0.452
3skgPB8Beta-secretase 13.4.23.460.452
3zc3FADFerredoxin--NADP reductase1.18.1.20.452
4bjcRPBTankyrase-22.4.2.300.452
4boeCLRJapanin/0.452
4bqzGNPEctonucleoside triphosphate diphosphohydrolase 2/0.452
4djw0KPBeta-secretase 13.4.23.460.452
4dus0MPBeta-secretase 13.4.23.460.452
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.452
4psbGA3Cytokinin-specific binding protein/0.452
5jinSAMHistone-lysine N-methyltransferase EHMT2/0.452
6stdMS2Scytalone dehydratase4.2.1.940.452
1eveE20Acetylcholinesterase3.1.1.70.451
1fkfFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.451
1fxvPNNPenicillin G acylase3.5.1.110.451
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.451
1v453DGPurine nucleoside phosphorylase2.4.2.10.451
1v48HA1Purine nucleoside phosphorylase2.4.2.10.451
2f99AKVAklanonic acid methyl ester cyclase AcmA5.5.1.230.451
2huqSAHDiphthine synthase/0.451
2oc9IMHPurine nucleoside phosphorylase2.4.2.10.451
2pdlTOLAldose reductase1.1.1.210.451
2uuoLK3UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.451
2v7qATPATP synthase subunit alpha, mitochondrial/0.451
2v7qATPATP synthase subunit beta, mitochondrial3.6.3.140.451
3dcsMZMCarbonic anhydrase 24.2.1.10.451
3dhcCYKN-acyl homoserine lactonase AiiA3.1.1.810.451
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3n71SFGHistone-lysine N-methyltransferase Smyd1/0.451
3p67FMNPentaerythritol tetranitrate reductase/0.451
3po6DT9Carbonic anhydrase 24.2.1.10.451
4a7b3W5Collagenase 33.4.240.451
4ba5PXGProbable aminotransferase/0.451
4bfd8T3Beta-secretase 13.4.23.460.451
4bfxZVXPantothenate kinase2.7.1.330.451
4briUNPEctonucleoside triphosphate diphosphohydrolase I/0.451
4bv9NDPKetimine reductase mu-crystallin1.5.1.250.451
4f9gC2EStimulator of interferon genes protein/0.451
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.451
4yfy1YJVioF/0.451
5ej9TPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.451
7stdCRPScytalone dehydratase4.2.1.940.451
1bwlFMNNADPH dehydrogenase 11.6.99.10.450
1ndzFR5Adenosine deaminase3.5.4.40.450
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.450
2cbqTH2Neocarzinostatin/0.450
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.450
2fs4PZ1Renin3.4.23.150.450
2fvc888Polyprotein/0.450
2hk9NAPShikimate dehydrogenase (NADP(+))/0.450
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.450
2hxzH7JCathepsin S3.4.22.270.450
2ji9ADPOxalyl-CoA decarboxylase4.1.1.80.450
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.450
2xysSY9Soluble acetylcholine receptor/0.450
3br3ETHTH-type transcriptional regulator QacR/0.450
3eq02TSProthrombin3.4.21.50.450
3fpdSAHHistone-lysine N-methyltransferase EHMT1/0.450
3ihzFK5Peptidylprolyl isomerase/0.450
3klbFMNUncharacterized protein/0.450
3vsxR32Renin3.4.23.150.450
3zraORBProgesterone receptor/0.450
4lxk1YTBeta-secretase 13.4.23.460.450
4lzwTHMUridine phosphorylase/0.450
4nv14TGFormyl transferase/0.450
4relKMPGlycosyltransferase/0.450
4u3jGTPTubulin beta chain/0.450
4yp12BAStimulator of interferon genes protein/0.450
5a88ADPRiboflavin biosynthesis protein RibF2.7.1.260.450
5ex0SAHHistone-lysine N-methyltransferase SMYD32.1.1.430.450
1a4wQWEProthrombin3.4.21.50.449
1f8gNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.449
1ghv120Prothrombin3.4.21.50.449
1gvrTNLPentaerythritol tetranitrate reductase/0.449
1mczTDPBenzoylformate decarboxylase4.1.1.70.449
1s0xC3SNuclear receptor ROR-alpha/0.449
1tllFMNNitric oxide synthase, brain1.14.13.390.449
1x1cSAHC-20 methyltransferase/0.449
1yw8A75Methionine aminopeptidase 2/0.449
2dv7SAHDiphthine synthase/0.449
2dxdANPNucleoside diphosphate kinase2.7.4.60.449
2eh4SAHDiphthine synthase/0.449
2ek3SAHDiphthine synthase/0.449
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.449
2ipjFFAAldo-keto reductase family 1 member C2/0.449
2iviACWIsopenicillin N synthase1.21.3.10.449
2jh5895Prothrombin3.4.21.50.449
2pb6SAHDiphthine synthase/0.449
2w6zL21Biotin carboxylase6.3.4.140.449
2zda32UProthrombin3.4.21.50.449
2zshGA3Gibberellin receptor GID1A30.449
3lpiZ74Beta-secretase 13.4.23.460.449
3ndcSAHPrecorrin-4 C(11)-methyltransferase2.1.1.1330.449
3v2jAZMCarbonic anhydrase 24.2.1.10.449
3v4tUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.449
3vv8B02Beta-secretase 13.4.23.460.449
4b1e6T6Beta-secretase 13.4.23.460.449
4kap1QVCarbonic anhydrase 24.2.1.10.449
4mlp2CXCryptochrome-2/0.449
4n4v2GYTankyrase-12.4.2.300.449
4nbh9CATerminal oxygenase component of carbazole/0.449
4r1fADPDNA topoisomerase 2-alpha5.99.1.30.449
4rp8ASCAscorbate-specific PTS system EIIC component/0.449
5d4uSAMUncharacterized protein MJ0489/0.449
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.449
1bl4AP1Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.448
1enpNADEnoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic1.3.1.90.448
1fncFDAFerredoxin--NADP reductase, chloroplastic1.18.1.20.448
1qgzFADFerredoxin--NADP reductase1.18.1.20.448
1qs2NADVip2Ac/0.448
1tl7FOKAdenylate cyclase type 2/0.448
1tl7FOKAdenylate cyclase type 5/0.448
1towCRZFatty acid-binding protein, adipocyte/0.448
1x27ASP_TYR_VAL_HIS_PTRTyrosine-protein kinase Lck2.7.10.20.448
2cy0NAPShikimate dehydrogenase (NADP(+))/0.448
2ekaSAHDiphthine synthase/0.448
2g20L1ARenin3.4.23.150.448
2huxSAHDiphthine synthase/0.448
2npfMOUElongation factor 2/0.448
2q94A04Methionine aminopeptidase/0.448
2vn1FK5Peptidylprolyl isomerase/0.448
2xujTZ5Acetylcholinesterase3.1.1.70.448
2xuoTZ4Acetylcholinesterase3.1.1.70.448
2zcvNDPQuinone oxidoreductase 21.6.5.20.448
2zg050UProthrombin3.4.21.50.448
3c1oNAPEugenol synthase/0.448
3ccbB2YDipeptidyl peptidase 4/0.448
3fr28CAFatty acid-binding protein, adipocyte/0.448
3junAJDPhenazine biosynthesis protein A/B/0.448
3q70RITCandidapepsin-23.4.23.240.448
3veu0GOBeta-secretase 13.4.23.460.448
4drjRAPSerine/threonine-protein kinase mTOR2.7.11.10.448
4drjRAPPeptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.448
4eilUMPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.448
4gts7TPGeranylgeranyl transferase type-2 subunit beta2.5.1.600.448
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.448
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.448
4layI63Peptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.448
4m0cFMNFMN-dependent NADH-azoreductase 1/0.448
4ure1PSCyclohexanol dehydrogenase/0.448
4wxfPLGSerine hydroxymethyltransferase/0.448
1fmjRTLRetinol dehydratase/0.447
1g63FMNEpidermin decarboxylase4.1.10.447
1jdzFMBPurine nucleoside phosphorylase/0.447
1je1GMPPurine nucleoside phosphorylase/0.447
1kw9BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.447
1lnmDTXBilin-binding protein/0.447
1tilATPAnti-sigma F factor/0.447
1trkTPPTransketolase 12.2.1.10.447
1ulbGUNPurine nucleoside phosphorylase2.4.2.10.447
1w87FADFerredoxin--NADP reductase1.18.1.20.447
1wxjIPLTryptophan synthase alpha chain/0.447
1xe65FPPlasmepsin-23.4.23.390.447
2e08SAHDiphthine synthase/0.447
2e16SAHDiphthine synthase/0.447
2j07HDFDeoxyribodipyrimidine photo-lyase4.1.99.30.447
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
2owvSAHDiphthine synthase/0.447
2pcgSAHDiphthine synthase/0.447
2pcmSAHDiphthine synthase/0.447
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.447
2wf3ZY3Beta-secretase 13.4.23.460.447
2zfq45UProthrombin3.4.21.50.447
2zfr46UProthrombin3.4.21.50.447
2zhf49UProthrombin3.4.21.50.447
2zi224UProthrombin3.4.21.50.447
3ixk929Beta-secretase 13.4.23.460.447
3ojiPYVAbscisic acid receptor PYL3/0.447
3r1rATPRibonucleoside-diphosphate reductase 1 subunit alpha1.17.4.10.447
3tqxPLP2-amino-3-ketobutyrate coenzyme A ligase/0.447
3wd9QPCcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.447
4b7754MBeta-secretase 13.4.23.460.447
4jicFMNGTN Reductase/0.447
4js1CTNBeta-galactoside alpha-2,6-sialyltransferase 12.4.99.10.447
4yp6NAPNicotinamide-nucleotide adenylyltransferase2.7.7.10.447
1cneFADNitrate reductase [NADH]1.7.1.10.446
1d3pBT3Prothrombin3.4.21.50.446
1dmwHBIPhenylalanine-4-hydroxylase1.14.16.10.446
1dr3HBIDihydrofolate reductase1.5.1.30.446
1e7qNAPGDP-L-fucose synthase/0.446
1lbbKAIGlutamate receptor 2/0.446
1m2hAPRNAD-dependent protein deacylase 1/0.446
1n5vNOMActVA 6 protein/0.446
1nvtNAPShikimate dehydrogenase (NADP(+))/0.446
1ta2176Prothrombin3.4.21.50.446
1wl4COAAcetyl-CoA acetyltransferase, cytosolic2.3.1.90.446
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.446
2dekSAHDiphthine synthase/0.446
2dsgSAHDiphthine synthase/0.446
2eh5SAHDiphthine synthase/0.446
2h21SAMRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic2.1.1.1270.446
2jlaTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.446
2owgSAHDiphthine synthase/0.446
2q96A18Methionine aminopeptidase/0.446
2r2mI50Prothrombin3.4.21.50.446
2wo7ASVIsopenicillin N synthase1.21.3.10.446
2wzwNDPNitroreductase NfnB/0.446
3bsa1PDGenome polyprotein2.7.7.480.446
3c14FOKAdenylate cyclase type 2/0.446
3c14FOKAdenylate cyclase type 5/0.446
3c7dNADOctopine dehydrogenase/0.446
3cotSTR3-oxo-5-beta-steroid 4-dehydrogenase/0.446
3dgaUMPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.446
3dsrADPV-type ATP synthase beta chain/0.446
3h7rNAPAldo-keto reductase family 4 member C8/0.446
3hgoFMN12-oxophytodienoate reductase 31.3.1.420.446
3lxeTORCarbonic anhydrase 14.2.1.10.446
3u9y09LTankyrase-22.4.2.300.446
3vswR31Renin3.4.23.150.446
4bfzZVZPantothenate kinase2.7.1.330.446
4i101BSBeta-secretase 13.4.23.460.446
4i6gFADCryptochrome-2/0.446
4lxa1YSBeta-secretase 13.4.23.460.446
4mvcCDCCholine-phosphate cytidylyltransferase A/0.446
1a9p9DIPurine nucleoside phosphorylase2.4.2.10.445
1b8nIMGPurine nucleoside phosphorylase2.4.2.10.445
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.445
1ny2ARG_PRO_PRO_GLYProthrombin3.4.21.50.445
1o76CAMCamphor 5-monooxygenase1.14.15.10.445
1p4aPCPPur operon repressor/0.445
1q84TZ4Acetylcholinesterase3.1.1.70.445
1w1wAGSStructural maintenance of chromosomes protein 1/0.445
2a9z26AAdenosine kinase2.7.1.200.445
2bdyUNBProthrombin3.4.21.50.445
2c42TPPPyruvate synthase/0.445
2ckmAA7Acetylcholinesterase3.1.1.70.445
2p6lSAHDiphthine synthase/0.445
2pnuENMAndrogen receptor/0.445
2uxoTACHTH-type transcriptional regulator TtgR/0.445
2w6pOA4Biotin carboxylase6.3.4.140.445
2xlpFADPutative flavin-containing monooxygenase/0.445
2ziq26UProthrombin3.4.21.50.445
3dd0EZLCarbonic anhydrase 24.2.1.10.445
3fgoACPSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.445
3gnvXNZGenome polyprotein2.7.7.480.445
3v0p4GWHisto-blood group ABO system transferase/0.445
4dc0NDPPutative ketoacyl reductase1.3.10.445
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.445
4fqsLYAThymidylate synthase ThyA/0.445
4j49NAIUncharacterized protein/0.445
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.445
4jiq1L5GTN Reductase/0.445
4l7h1W1Beta-secretase 13.4.23.460.445
4lutDCSAlanine racemase/0.445
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.444
1cjtFOKAdenylate cyclase type 2/0.444
1cjtFOKAdenylate cyclase type 5/0.444
1fkbRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.444
1giqNAIIota toxin component Ia/0.444
1obnASVIsopenicillin N synthase1.21.3.10.444
1psa0ZLPepsin A3.4.23.10.444
1s3uTQDDihydrofolate reductase1.5.1.30.444
1tduCB3Thymidylate synthase/0.444
1wngSAHDiphthine synthase/0.444
1ypgUIRProthrombin3.4.21.50.444
2gvdFKPAdenylate cyclase type 2/0.444
2gvdFKPAdenylate cyclase type 5/0.444
2tprFADTrypanothione reductase1.8.1.120.444
2vd4P21Bifunctional protein GlmU/0.444
2wmdZZ0NmrA-like family domain-containing protein 1/0.444
3ce0P34Poly [ADP-ribose] polymerase 32.4.2.300.444
3dvaTPWPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.444
3dvaTPWPyruvate dehydrogenase E1 component subunit beta1.2.4.10.444
3f8wADNPurine nucleoside phosphorylase/0.444
3i0pNADMalate dehydrogenase, putative/0.444
3imxB84Glucokinase2.7.1.20.444
3l3lL3LPoly [ADP-ribose] polymerase 12.4.2.300.444
3n3bFMNProtein NrdI/0.444
3nxrD2DDihydrofolate reductase1.5.1.30.444
3oafOAGDihydrofolate reductase1.5.1.30.444
3orfNADDihydropteridine reductase1.5.1.340.444
3ox279XRibosyldihydronicotinamide dehydrogenase [quinone]/0.444
3rq8AP5ADP-dependent (S)-NAD(P)H-hydrate dehydratase/0.444
3s55NADPutative short-chain dehydrogenase/reductase/0.444
3zoiM2WIsopenicillin N synthase1.21.3.10.444
4cd2FOLDihydrofolate reductase1.5.1.30.444
4de2DN3Beta-lactamase/0.444
4i1nFOLDihydrofolate reductase1.5.1.30.444
4o6fSAHN-lysine methyltransferase SMYD2/0.444
1bzfTMQDihydrofolate reductase1.5.1.30.443
1cjvFOKAdenylate cyclase type 2/0.443
1cjvFOKAdenylate cyclase type 5/0.443
1cqp803Integrin alpha-L/0.443
1dr3TAPDihydrofolate reductase1.5.1.30.443
1dx6GNTAcetylcholinesterase3.1.1.70.443
1e64FADFerredoxin--NADP reductase1.18.1.20.443
1e6vCOMMethyl-coenzyme M reductase I subunit alpha/0.443
1e6vCOMMethyl coenzyme M reductase, beta subunit/0.443
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.443
1g28FMNPHY3/0.443
1if7SBRCarbonic anhydrase 24.2.1.10.443
1mq0BRDCytidine deaminase3.5.4.50.443
1pq6965Oxysterols receptor LXR-beta/0.443
1suoCPZCytochrome P450 2B41.14.14.10.443
1tqf32PBeta-secretase 13.4.23.460.443
1w19T5P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.443
2e8sSAHDiphthine synthase/0.443
2h4nAZMCarbonic anhydrase 24.2.1.10.443
2lfoGCHFatty acid-binding protein, liver/0.443
2pdaTPPPyruvate synthase/0.443
2qiqCYVReplicase polyprotein 1ab/0.443
2vtdLKMUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.443
3c3xNAPEugenol synthase 11.1.1.3180.443
3cavCI23-oxo-5-beta-steroid 4-dehydrogenase/0.443
3cuiX4SExoglucanase/xylanase3.2.1.910.443
3imeBZ2Pantothenate synthetase6.3.2.10.443
3lzwNAPFerredoxin--NADP reductase 21.18.1.20.443
3nxtD2EDihydrofolate reductase1.5.1.30.443
3zdnFADMonoamine oxidase N1.4.3.40.443
4b63NAPL-ornithine N(5)-monooxygenase/0.443
4bamMM9Prothrombin3.4.21.50.443
4ead0NPThymidine phosphorylase2.4.2.40.443
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
4gddNAIUDP-galactopyranose mutase/0.443
4jubTPPBenzoylformate decarboxylase4.1.1.70.443
4mt92D6Tankyrase-12.4.2.300.443
4n5nNAPAcetoacetyl-CoA reductase1.1.1.360.443
4zvnFADRibosyldihydronicotinamide dehydrogenase [quinone]/0.443
4u140HKMuscarinic acetylcholine receptor M3/0.443
1ao8MTXDihydrofolate reductase1.5.1.30.442
1dhfFOLDihydrofolate reductase1.5.1.30.442
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.442
1n3sGTPGTP cyclohydrolase 13.5.4.160.442
1nj5P5AProline--tRNA ligase/0.442
1pq944BOxysterols receptor LXR-beta/0.442
1pvgANPDNA topoisomerase 25.99.1.30.442
1qrsATPGlutamine--tRNA ligase6.1.1.180.442
1u65CP0Acetylcholinesterase3.1.1.70.442
1zrb062Prothrombin3.4.21.50.442
2a9y26AAdenosine kinase2.7.1.200.442
2ea2F77Methionine aminopeptidase 2/0.442
2eglSAHDiphthine synthase/0.442
2ha6SCKAcetylcholinesterase3.1.1.70.442
2qe2452Polyprotein/0.442
2xnpWCXSerine/threonine-protein kinase Nek22.7.11.10.442
3ed1GA3Gibberellin receptor GID1/0.442
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.442
3geyP34Poly [ADP-ribose] polymerase 152.4.2.300.442
3h3t16HCollagen type IV alpha-3-binding protein/0.442
3hatGLY_VAL_ARG_RNGProthrombin3.4.21.50.442
3ipkPMSSurface protein adhesin/0.442
3p74FMNPentaerythritol tetranitrate reductase/0.442
3p80P80Pentaerythritol tetranitrate reductase/0.442
3rbqGLY_ALA_GLY_ALA_DAOProtein unc-119 homolog A/0.442
3vkjFNRIsopentenyl-diphosphate delta-isomerase/0.442
4arbC57Acetylcholinesterase3.1.1.70.442
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.442
4dch4DCGlucokinase2.7.1.20.442
4dk70KSOxysterols receptor LXR-beta/0.442
4dro0MDPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.442
4du6GTPGTP cyclohydrolase 1/0.442
4hyf1AKTankyrase-22.4.2.300.442
4jpc1M6Beta-secretase 13.4.23.460.442
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.442
4rvdSAMD-mycarose 3-C-methyltransferase/0.442
4zqcF6FTryptophan synthase alpha chain/0.442
5c1d12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.442
1bjkFADFerredoxin--NADP reductase1.18.1.20.441
1hb1OCVIsopenicillin N synthase1.21.3.10.441
1ivsVAAValine--tRNA ligase6.1.1.90.441
1nzq162Prothrombin3.4.21.50.441
1pu9COAHAT A1/0.441
1qsnCOAHAT A1/0.441
1rx7FOLDihydrofolate reductase1.5.1.30.441
1upw444Oxysterols receptor LXR-beta/0.441
1w4lGL8Acetylcholinesterase3.1.1.70.441
1xvtCOAL-carnitine CoA-transferase/0.441
2cjeDUNDUTPase/0.441
2g0bNLTLong-chain N-acyl amino acid synthase/0.441
2gnaGDUUDP-N-acetylglucosamine 4,6-dehydratase (inverting)4.2.1.1150.441
2weaPP6Penicillopepsin-13.4.23.200.441
2yd0BESEndoplasmic reticulum aminopeptidase 13.4.110.441
2zhq27UProthrombin3.4.21.50.441
3a26MTAtRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase/0.441
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.441
3ekuCY9Actin-5C/0.441
3fpkFADFerredoxin-NADP reductase/0.441
3nxvD2FDihydrofolate reductase1.5.1.30.441
3qizQI2Botulinum neurotoxin type A3.4.24.690.441
3s3vTOPDihydrofolate reductase1.5.1.30.441
3sbhE65Carbonic anhydrase 24.2.1.10.441
3tg4SAMN-lysine methyltransferase SMYD2/0.441
4b68FADL-ornithine N(5)-monooxygenase/0.441
4b6l9ZPSerine/threonine-protein kinase PLK32.7.11.210.441
4djx0KQBeta-secretase 13.4.23.460.441
4eu8COASuccinyl-CoA:acetate CoA-transferase/0.441
4ey6GNTAcetylcholinesterase3.1.1.70.441
4frjDWBBeta-secretase 13.4.23.460.441
4i13FOLDihydrofolate reductase1.5.1.30.441
4jtrIZPAldo-keto reductase family 1 member C2/0.441
4loi1YCStimulator of interferon genes protein/0.441
5ah5LSSLeucine--tRNA ligase/0.441
1bk0ACVIsopenicillin N synthase1.21.3.10.440
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.440
1kqnNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.440
1mu8CDBProthrombin3.4.21.50.440
1x27ASP_ASP_TYR_VAL_PTRTyrosine-protein kinase Lck2.7.10.20.440
1xvvCCQL-carnitine CoA-transferase/0.440
1zgi382Prothrombin3.4.21.50.440
2abaSTRPentaerythritol tetranitrate reductase/0.440
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2e7rSAHDiphthine synthase/0.440
2gfxPMN3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.440
2he5NDPAldo-keto reductase family 1 member C211.1.10.440
2xncFADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.440
3a20FMNFMN-binding protein/0.440
3dc3AZMCarbonic anhydrase 24.2.1.10.440
3i0aDBHNeutrophil gelatinase-associated lipocalin/0.440
3ivcFG4Pantothenate synthetase6.3.2.10.440
3juqAJDPhenazine biosynthesis protein A/B/0.440
3l3mA92Poly [ADP-ribose] polymerase 12.4.2.300.440
3o7bSAHRibosomal RNA small subunit methyltransferase Nep1/0.440
3oikWZBCarbonic anhydrase 24.2.1.10.440
3s41S41Glucokinase2.7.1.20.440
3swqEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.440
3t94MTAS-methyl-5'-thioadenosine phosphorylase/0.440
4awtFMNNADH:flavin oxidoreductase Sye1/0.440
4ef4C2EStimulator of interferon genes protein/0.440
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.440
4h3j10WBeta-secretase 13.4.23.460.440
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.440
4k9oTPPBenzoylformate decarboxylase4.1.1.70.440
4ke01R8Beta-secretase 13.4.23.460.440
4qohSTLRibosyldihydronicotinamide dehydrogenase [quinone]/0.440
4zzjCNANAD-dependent protein deacetylase sirtuin-13.5.10.440
5a4wQCTGlutathione S-transferase F22.5.1.180.440
8catNDPCatalase1.11.1.60.440