scPDB - 2e1m entry

Protein Data Bank Entry:

PDB ID : 2e1m

Resolution :2.800 Å

Experimental Method : X-ray

Deposition Date : 2006-10-26

Activity from ChEMBL: What is pChEMBL ?

	Min	Mean	Median	Standard Deviation	Max	Count
pChEMBL:

List of CHEMBLId :

Binding Site :

Uniprot Annotation

Name:	L-glutamate oxidase
ID:	Q8L3C7_9ACTN
AC:	Q8L3C7
Organism:	Streptomyces sp. X-119-6
Reign:	Bacteria
TaxID:	196112
EC Number:	/

Chains:

Chain Name:	Percentage of Residues within binding site
A	48 %
B	13 %
C	39 %

Ligand binding site composition:

B-Factor:	24.427
Number of residues:	67
Including
Standard Amino Acids:	67
Non Standard Amino Acids:	0
Water Molecules:	0
Cofactors:
Metals:

Cavity properties

Ligandability	Volume (Å3)
0.507	560.250

% Hydrophobic	% Polar
50.00	50.00
According to VolSite

Ligand :

HET Code:	FAD
Formula:	C27H31N9O15P2
Molecular weight:	783.534 g/mol
DrugBank ID:	DB03147
Buried Surface Area:	78.3 %
Polar Surface area:	381.7 Å2

Number of
H-Bond Acceptors:	22
H-Bond Donors:	7
Rings:	6
Aromatic rings:	3
Anionic atoms:	2
Cationic atoms:	0
Rule of Five Violation:	3
Rotatable Bonds:	13

Mass center Coordinates

X	Y	Z
13.1664	54.3137	85.2206

Binding mode :

What is Poseview ?

2D View
3D View

Image generated by PoseView

Protein

Binding Site

Ligand

Interaction pattern

hydrophobic (CA)

aromatic (CZ)

hydrogen bond acceptor (O)

hydrogen bond acceptor/donor (OG)

hydrogen bond donor (N)

positively ionized (NZ)

negatively ionized (OD1)

metal (ZN)

Legend:

Represent the protein/ligand binding mode, centered on the ligand
Dashed lines represents hydrogen bonds and metal interactions
Green residue labels for amino acids with hydrophobic contacts (green lines) to the ligand

Image generated using PoseView by BioSolveIT

Ligand	Protein		Interaction
Atom	Atom	Residue	Distance (Å)	Angle (°)	Type
C4'	CG2	ILE- 68	4.16	0	Hydrophobic	false
O1P	N	ALA- 69	2.84	155.2	H-Bond (Protein Donor)	false
O3B	OE2	GLU- 88	3.02	168.09	H-Bond (Ligand Donor)	false
O2B	OE1	GLU- 88	2.73	158.15	H-Bond (Ligand Donor)	false
N3A	N	ALA- 89	2.9	152.45	H-Bond (Protein Donor)	false
O1A	N	ARG- 97	2.98	161.21	H-Bond (Protein Donor)	false
O2A	NE	ARG- 97	2.71	160.44	H-Bond (Protein Donor)	false
O2A	NH2	ARG- 97	3.21	130.78	H-Bond (Protein Donor)	false
O3P	NH2	ARG- 97	3.17	123.46	H-Bond (Protein Donor)	false
O2A	CZ	ARG- 97	3.38	0	Ionic (Protein Cationic)	false
C8M	CG	ARG- 97	4.1	0	Hydrophobic	false
C9	CB	ARG- 97	4.37	0	Hydrophobic	false
C3'	CB	ARG- 97	4.36	0	Hydrophobic	false
C9A	CB	ALA- 122	4.28	0	Hydrophobic	false
C2'	CB	ALA- 122	4.47	0	Hydrophobic	false
O4	N	MET- 123	3	167.42	H-Bond (Protein Donor)	false
N3	O	ARG- 124	2.78	163.01	H-Bond (Ligand Donor)	false
O4	N	ARG- 124	2.93	162.89	H-Bond (Protein Donor)	false
N6A	O	MET- 354	3.14	172.37	H-Bond (Ligand Donor)	false
N1A	N	MET- 354	2.82	153.63	H-Bond (Protein Donor)	false
C1B	CG2	ILE- 405	4.07	0	Hydrophobic	false
N7A	OG	SER- 409	2.85	159.49	H-Bond (Protein Donor)	false
C7M	CD	LYS- 437	4.11	0	Hydrophobic	false
C7M	CE1	TYR- 562	4.27	0	Hydrophobic	false
C7M	CE2	TRP- 608	4.48	0	Hydrophobic	false
C8M	CD2	TRP- 608	3.74	0	Hydrophobic	false
C2B	CB	TYR- 613	3.88	0	Hydrophobic	false
C8M	CG	GLU- 617	3.24	0	Hydrophobic	false
C7	CG	GLU- 617	4.1	0	Hydrophobic	false
C8	CG	GLU- 617	3.53	0	Hydrophobic	false
O2P	N	GLU- 645	2.83	140.37	H-Bond (Protein Donor)	false
C5'	CB	GLU- 645	3.41	0	Hydrophobic	false
O2	N	ILE- 654	3.04	164.27	H-Bond (Protein Donor)	false
C2'	CG1	ILE- 654	3.9	0	Hydrophobic	false
C4'	CG1	ILE- 654	4.48	0	Hydrophobic	false
C5'	CB	ALA- 657	4.15	0	Hydrophobic	false