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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4m2rBZ1Carbonic anhydrase 24.2.1.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
4m2rBZ1Carbonic anhydrase 24.2.1.11.000
4kap1QVCarbonic anhydrase 24.2.1.10.881
3dc3AZMCarbonic anhydrase 24.2.1.10.879
4m2vBZ1Carbonic anhydrase 24.2.1.10.826
3qykIE2Carbonic anhydrase 24.2.1.10.825
3m5eJDRCarbonic anhydrase 24.2.1.10.814
1bn4AL9Carbonic anhydrase 24.2.1.10.806
3dcsMZMCarbonic anhydrase 24.2.1.10.805
1bntAL2Carbonic anhydrase 24.2.1.10.768
1g52F2BCarbonic anhydrase 24.2.1.10.765
3f4xKLTCarbonic anhydrase 24.2.1.10.764
3mhlJ71Carbonic anhydrase 24.2.1.10.762
3t84SG6Carbonic anhydrase 24.2.1.10.761
1g1dFSBCarbonic anhydrase 24.2.1.10.752
1g4oBSBCarbonic anhydrase 24.2.1.10.751
1kwrSG2Carbonic anhydrase 24.2.1.10.750
1if7SBRCarbonic anhydrase 24.2.1.10.749
4bf6X0QCarbonic anhydrase 24.2.1.10.749
1bn1AL5Carbonic anhydrase 24.2.1.10.748
1bnwTPDCarbonic anhydrase 24.2.1.10.739
1bnqAL4Carbonic anhydrase 24.2.1.10.738
1g45FSBCarbonic anhydrase 24.2.1.10.738
4iwz1GOCarbonic anhydrase 24.2.1.10.737
3d9zD9ZCarbonic anhydrase 24.2.1.10.735
1a42BZUCarbonic anhydrase 24.2.1.10.734
3m2nJ74Carbonic anhydrase 24.2.1.10.730
1i91INQCarbonic anhydrase 24.2.1.10.726
4k13ETSCarbonic anhydrase 24.2.1.10.722
2x7tWZBCarbonic anhydrase 24.2.1.10.720
3t82SG4Carbonic anhydrase 24.2.1.10.720
2h15B19Carbonic anhydrase 24.2.1.10.718
3kigDA4Carbonic anhydrase 24.2.1.10.718
1bnnAL1Carbonic anhydrase 24.2.1.10.715
3hkuTORCarbonic anhydrase 24.2.1.10.715
4itoMPXCarbonic anhydrase 24.2.1.10.714
5fltVJJCarbonic anhydrase 24.2.1.10.714
2eu3FF3Carbonic anhydrase 24.2.1.10.713
3n4bWWZCarbonic anhydrase 24.2.1.10.711
1cilETSCarbonic anhydrase 24.2.1.10.710
2wejFB2Carbonic anhydrase 24.2.1.10.706
1if5FBTCarbonic anhydrase 24.2.1.10.705
3oysOYSCarbonic anhydrase 24.2.1.10.703
3eft3BSCarbonic anhydrase 24.2.1.10.702
3po6DT9Carbonic anhydrase 24.2.1.10.701
3sbiE90Carbonic anhydrase 24.2.1.10.695
4itp1GDCarbonic anhydrase 24.2.1.10.695
1kwqSG1Carbonic anhydrase 24.2.1.10.693
3dazMZMCarbonic anhydrase 24.2.1.10.693
4ilx1EZCarbonic anhydrase 24.2.1.10.691
3m98E02Carbonic anhydrase 24.2.1.10.690
3b4fTUOCarbonic anhydrase 24.2.1.10.687
1i9mINWCarbonic anhydrase 24.2.1.10.685
3k2fNKXCarbonic anhydrase 24.2.1.10.684
1if6FBUCarbonic anhydrase 24.2.1.10.683
3nb5R21Carbonic anhydrase 24.2.1.10.683
3mhcARZCarbonic anhydrase 24.2.1.10.682
2h4nAZMCarbonic anhydrase 24.2.1.10.681
3dbuD8WCarbonic anhydrase 24.2.1.10.678
3mhoJ43Carbonic anhydrase 24.2.1.10.678
3mzcS6ICarbonic anhydrase 24.2.1.10.677
3n0nP9BCarbonic anhydrase 24.2.1.10.677
2wehFB1Carbonic anhydrase 24.2.1.10.674
3m67E36Carbonic anhydrase 24.2.1.10.673
4k0tD9ZCarbonic anhydrase 24.2.1.10.673
1g4jFFBCarbonic anhydrase 24.2.1.10.668
3ni5C1HCarbonic anhydrase 24.2.1.10.667
3m40J45Carbonic anhydrase 24.2.1.10.666
1bn3AL6Carbonic anhydrase 24.2.1.10.665
3l14I7BCarbonic anhydrase 24.2.1.10.662
3m2yBE0Carbonic anhydrase 24.2.1.10.662
3n2pAYXCarbonic anhydrase 24.2.1.10.662
3s9tE49Carbonic anhydrase 24.2.1.10.662
4bf19FKCarbonic anhydrase 24.2.1.10.659
1bnmAL8Carbonic anhydrase 24.2.1.10.657
3mnaDWHCarbonic anhydrase 24.2.1.10.656
1g54FFBCarbonic anhydrase 24.2.1.10.655
1if4FBSCarbonic anhydrase 24.2.1.10.655
3betCTFCarbonic anhydrase 24.2.1.10.651
1oklMNSCarbonic anhydrase 24.2.1.10.650
1i9nIOACarbonic anhydrase 24.2.1.10.648
1zsbAZMCarbonic anhydrase 24.2.1.10.648
1if8SBSCarbonic anhydrase 24.2.1.10.647
4kniE1ECarbonic anhydrase 24.2.1.10.645
2x7uWZACarbonic anhydrase 24.2.1.10.644
3saxE50Carbonic anhydrase 24.2.1.10.644
3t85SG7Carbonic anhydrase 24.2.1.10.643
3igpDT7Carbonic anhydrase 24.2.1.10.642
3ffpLC1Carbonic anhydrase 24.2.1.10.640
4n16CHDCarbonic anhydrase 24.2.1.10.638
3mdzEZLCarbonic anhydrase 74.2.1.10.637
1ttm667Carbonic anhydrase 24.2.1.10.636
3s8xE59Carbonic anhydrase 24.2.1.10.631
3sbhE65Carbonic anhydrase 24.2.1.10.631
3mhiJ90Carbonic anhydrase 24.2.1.10.630
1xpz4TZCarbonic anhydrase 24.2.1.10.625
3ml2SU0Carbonic anhydrase 24.2.1.10.625
3dcwEZLCarbonic anhydrase 24.2.1.10.623
3d8wD8WCarbonic anhydrase 24.2.1.10.621
3oyqOYQCarbonic anhydrase 24.2.1.10.620
1i90INMCarbonic anhydrase 24.2.1.10.618
4pxxCHDCarbonic anhydrase 24.2.1.10.618
2weoFBWCarbonic anhydrase 24.2.1.10.617
1i8zINLCarbonic anhydrase 24.2.1.10.615
2wd2MS5Carbonic anhydrase 24.2.1.10.615
1i9qIOFCarbonic anhydrase 24.2.1.10.611
1oq5CELCarbonic anhydrase 24.2.1.10.611
3m96E38Carbonic anhydrase 24.2.1.10.611
1jd0AZMCarbonic anhydrase 124.2.1.10.607
1ydaAZMCarbonic anhydrase 24.2.1.10.606
1i9pIOECarbonic anhydrase 24.2.1.10.605
3mmfD9HCarbonic anhydrase 24.2.1.10.605
4x5sAZMCarbonic anhydrase (Carbonate dehydratase)/0.605
3myqE27Carbonic anhydrase 24.2.1.10.604
4kp8E1GCarbonic anhydrase 124.2.1.10.604
4mo82VQCarbonic anhydrase 24.2.1.10.603
1cnyEG3Carbonic anhydrase 24.2.1.10.601
3oy0OY0Carbonic anhydrase 24.2.1.10.601
1xq04TRCarbonic anhydrase 24.2.1.10.599
1cnxEG2Carbonic anhydrase 24.2.1.10.598
3dccD9ZCarbonic anhydrase 24.2.1.10.598
3zncBZ1Carbonic anhydrase 44.2.1.10.598
1bnuAL3Carbonic anhydrase 24.2.1.10.597
4knjE1FCarbonic anhydrase 24.2.1.10.594
3f7bAG5Carbonic anhydrase 44.2.1.10.591
3f7uAG4Carbonic anhydrase 44.2.1.10.591
3oimVZ5Carbonic anhydrase 24.2.1.10.591
1bnvAL7Carbonic anhydrase 24.2.1.10.590
4dz7D02Carbonic anhydrase 24.2.1.10.590
2powI7CCarbonic anhydrase 24.2.1.10.588
3n3jWWVCarbonic anhydrase 24.2.1.10.588
4ht2V50Carbonic anhydrase 124.2.1.10.588
3oikWZBCarbonic anhydrase 24.2.1.10.586
3fw3ETSCarbonic anhydrase 44.2.1.10.584
2wegFBVCarbonic anhydrase 24.2.1.10.581
4uovAZMCarbonate dehydratase/0.581
1oknSTBCarbonic anhydrase 24.2.1.10.579
4kp5E1FCarbonic anhydrase 124.2.1.10.575
3dd82C7Carbonic anhydrase 24.2.1.10.574
3p5lIT5Carbonic anhydrase 24.2.1.10.573
3bl1BL1Carbonic anhydrase 24.2.1.10.572
4lu3AZMCarbonic anhydrase 144.2.1.10.565
3dd0EZLCarbonic anhydrase 24.2.1.10.561
1okmSABCarbonic anhydrase 24.2.1.10.553
1rj6AZMCarbonic anhydrase 144.2.1.10.552
4k0zMZMCarbonic anhydrase 24.2.1.10.551
3v2jAZMCarbonic anhydrase 24.2.1.10.543
1cnwEG1Carbonic anhydrase 24.2.1.10.542
2q1qOSPCarbonic anhydrase 24.2.1.10.538
3h3r14HCollagen type IV alpha-3-binding protein/0.522
3rz8RZ8Carbonic anhydrase 24.2.1.10.521
3zbsOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.515
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.510
4iae1DXAlr2278 protein/0.510
3h3t16HCollagen type IV alpha-3-binding protein/0.509
2y1tDUDSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.508
3f03FMNPentaerythritol tetranitrate reductase/0.508
1dmyAZMCarbonic anhydrase 5A, mitochondrial4.2.1.10.507
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.506
1vyrFMNPentaerythritol tetranitrate reductase/0.505
3h3qH13Collagen type IV alpha-3-binding protein/0.505
1i7pFADNADH-cytochrome b5 reductase 31.6.2.20.504
1kbiFMNCytochrome b2, mitochondrial1.1.2.30.504
3elbC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.504
3lxeTORCarbonic anhydrase 14.2.1.10.504
3p74FMNPentaerythritol tetranitrate reductase/0.504
7stdCRPScytalone dehydratase4.2.1.940.504
1h50FMNPentaerythritol tetranitrate reductase/0.503
1uxjNADMalate dehydrogenase/0.502
2abbFMNPentaerythritol tetranitrate reductase/0.502
3apwDP0Alpha-1-acid glycoprotein 2/0.502
3p62FMNPentaerythritol tetranitrate reductase/0.502
1foaUD1Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase2.4.1.1010.501
4knmE1ECarbonic anhydrase 134.2.1.10.501
1xe65FPPlasmepsin-23.4.23.390.500
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.500
1o9bNAIQuinate/shikimate dehydrogenase/0.497
1w6hTITPlasmepsin-23.4.23.390.497
2rqfJH3Hemolymph juvenile hormone binding protein/0.497
2zvcSAHPrecorrin-3 C17-methyltransferase/0.497
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.497
1icqFMN12-oxophytodienoate reductase 11.3.1.420.495
3up4FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.495
2dxdANPNucleoside diphosphate kinase2.7.4.60.494
1ndhFADNADH-cytochrome b5 reductase 31.6.2.20.493
3ixp834Ecdysone receptor/0.493
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.492
2d29FADAcyl-CoA dehydrogenase/0.491
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.489
2zvbSAHPrecorrin-3 C17-methyltransferase/0.489
4bfzZVZPantothenate kinase2.7.1.330.489
1h51FMNPentaerythritol tetranitrate reductase/0.488
2yozOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.488
3i0pNADMalate dehydrogenase, putative/0.488
3zs7ATPPyridoxine/pyridoxal/pyridoxamine kinase/0.488
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.487
3qvpFADGlucose oxidase1.1.3.40.487
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.486
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.486
4jqh1MFAlr2278 protein/0.486
2fxuBIDActin, alpha skeletal muscle/0.485
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.485
3l6jZ90Alr2278 protein/0.485
3qvrFADGlucose oxidase1.1.3.40.484
4du82P0Mevalonate diphosphate decarboxylase/0.484
4n1gCEIObelin/0.484
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.483
4iah1DXAlr2278 protein/0.483
1y9dTPPPyruvate oxidase1.2.3.30.482
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.482
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.482
3nmpPYVAbscisic acid receptor PYL2/0.482
4a802ANMajor pollen allergen Bet v 1-A/0.482
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.482
6stdMS2Scytalone dehydratase4.2.1.940.482
3mddFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.481
1n4sCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.480
1rneC60Renin3.4.23.150.480
2i65NADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.480
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.480
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.480
3lpkZ76Beta-secretase 13.4.23.460.480
4a862ANMajor pollen allergen Bet v 1-A/0.480
4gddNAIUDP-galactopyranose mutase/0.480
1kp2ATPArgininosuccinate synthase6.3.4.50.479
2g1n1IGRenin3.4.23.150.479
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.479
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.479
3g70A5TRenin3.4.23.150.479
3qt62P0Mevalonate diphosphate decarboxylase/0.479
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.479
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.479
3gfbNADL-threonine 3-dehydrogenase/0.478
1kbjFMNCytochrome b2, mitochondrial1.1.2.30.477
1w34FADFerredoxin--NADP reductase1.18.1.20.477
2i7pACOPantothenate kinase 32.7.1.330.477
3aezGDPPantothenate kinase2.7.1.330.477
1iayAVG1-aminocyclopropane-1-carboxylate synthase 24.4.1.140.476
1nvtNAPShikimate dehydrogenase (NADP(+))/0.476
1xseNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.476
2j3qTFLAcetylcholinesterase3.1.1.70.476
2xtnGTPGTPase IMAP family member 2/0.476
2x06NADL-sulfolactate dehydrogenase/0.475
3gkaFMNN-ethylmaleimide reductase/0.475
4fxy0W2Neurolysin, mitochondrial3.4.24.160.475
4xrbNDPPossible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc/0.475
1akbPPDAspartate aminotransferase, mitochondrial2.6.1.10.474
1bwsNDPGDP-L-fucose synthase/0.474
1c9wNAPAldose reductase-related protein 2/0.474
1drhNAPDihydrofolate reductase1.5.1.30.474
1kfbIGPTryptophan synthase alpha chain/0.474
1r58AO5Methionine aminopeptidase 2/0.474
3akn11DFatty acid-binding protein, intestinal/0.474
3t3q9PLCytochrome P450 2A61.14.130.474
4a8v2ANMajor pollen allergen Bet v 1-J/0.474
4dptAGSMevalonate diphosphate decarboxylase/0.474
4ef4C2EStimulator of interferon genes protein/0.474
4zlaBESCytosol aminopeptidase3.4.11.10.474
1q6iFK5FKBP-type peptidyl-prolyl cis-trans isomerase FkpA5.2.1.80.473
1qrpHH0Pepsin A-43.4.23.10.473
1szfFMNCytochrome b2, mitochondrial1.1.2.30.473
1uxyEPUUDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.473
3kjgADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.473
3p67FMNPentaerythritol tetranitrate reductase/0.473
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.473
4q71FADBifunctional protein PutA/0.473
1b8vNADMalate dehydrogenase/0.472
1kkq471Peroxisome proliferator-activated receptor alpha/0.472
1r5gAO1Methionine aminopeptidase 2/0.472
2hs8FMN12-oxophytodienoate reductase 31.3.1.420.472
3a0tADPSensor histidine kinase/0.472
3cotSTR3-oxo-5-beta-steroid 4-dehydrogenase/0.472
3fhxPLPPyridoxal kinase2.7.1.350.472
3gwfNAPCyclohexanone monooxygenase/0.472
3ziuLSSLeucyl-tRNA synthetase/0.472
4jicFMNGTN Reductase/0.472
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.472
4ycoFMNtRNA-dihydrouridine(16) synthase/0.472
4yj2GTPTubulin alpha-1B chain/0.472
1icpFMN12-oxophytodienoate reductase 11.3.1.420.471
1xddAAYIntegrin alpha-L/0.471
2wqpWQPPolysialic acid capsule biosynthesis protein SiaC/0.471
2zbaZBATrichothecene 3-O-acetyltransferase/0.471
3junAJDPhenazine biosynthesis protein A/B/0.471
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.471
4zj8SUVOrexin receptor type 1/0.471
1ju2FAD(R)-mandelonitrile lyase 24.1.2.100.470
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.470
1q84TZ4Acetylcholinesterase3.1.1.70.470
1rszDIHPurine nucleoside phosphorylase2.4.2.10.470
1towCRZFatty acid-binding protein, adipocyte/0.470
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.470
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.470
3p84FMNPentaerythritol tetranitrate reductase/0.470
3wczNAPAldo-keto reductase AKR2E4/0.470
4buuF38Tankyrase-22.4.2.300.470
4fmxCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.470
4fryNADPutative signal-transduction protein with CBS domains/0.470
4m83ERYOleandomycin glycosyltransferase2.4.10.470
4w5kPLPAspartate aminotransferase, mitochondrial/0.470
1bdmNAXMalate dehydrogenase/0.469
1h63FMNPentaerythritol tetranitrate reductase/0.469
1x1dSAHC-20 methyltransferase/0.469
1xe55FEPlasmepsin-23.4.23.390.469
3giyFMN(S)-mandelate dehydrogenase1.1.99.310.469
3m1vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.469
3m1vCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.469
3uzxAOX3-oxo-5-beta-steroid 4-dehydrogenase/0.469
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.469
5dw60T1Succinyl-CoA:acetate CoA-transferase/0.469
1qpf858Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.468
1xz85GPBifunctional protein PyrR2.4.2.90.468
2q3rFMN12-oxophytodienoate reductase 11.3.1.420.468
3iqhTYR_ASP_ILECysteine synthase2.5.1.470.468
4a83DXCMajor pollen allergen Bet v 1-A/0.468
4dbc3QPAspartate aminotransferase2.6.1.10.468
4dbzNDPPutative ketoacyl reductase1.3.10.468
4tlzNAPKtzI/0.468
4tmbFMNOld yellow enzyme/0.468
1culFOKAdenylate cyclase type 2/0.467
1culFOKAdenylate cyclase type 5/0.467
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.467
2cy0NAPShikimate dehydrogenase (NADP(+))/0.467
2dvlFADAcyl-CoA dehydrogenase/0.467
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.467
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.467
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.467
3hgrFMN12-oxophytodienoate reductase 11.3.1.420.467
3lpiZ74Beta-secretase 13.4.23.460.467
3otwCOAPhosphopantetheine adenylyltransferase/0.467
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.467
4i6gFADCryptochrome-2/0.467
4q0kGA3Phytohormone-binding protein/0.467
5a0112VO-glycosyltransferase/0.467
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.466
1qy8RDIEndoplasmin/0.466
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.466
1txtCAAHMG-CoA synthase/0.466
2fk8SAMHydroxymycolate synthase MmaA42.1.10.466
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.466
2qimZEAClass 10 plant pathogenesis-related protein/0.466
3b6pTMPThree-prime repair exonuclease 13.1.11.20.466
3e6yCW114-3-3-like protein C/0.466
3ekuCY9Actin-5C/0.466
3k8q22APurine nucleoside phosphorylase2.4.2.10.466
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.466
1j49NADD-lactate dehydrogenase1.1.1.280.465
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.465
1vbiNADMalate/L-lactate dehydrogenase family protein/0.465
1vjiFMN12-oxophytodienoate reductase 11.3.1.420.465
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.465
2e77FMNLactate oxidase/0.465
2g247IGRenin3.4.23.150.465
3bhtMFRCyclin-dependent kinase 22.7.11.220.465
3nl6TPSUncharacterized protein/0.465
3pghFLPProstaglandin G/H synthase 21.14.99.10.465
3qw4U5POrotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative/0.465
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.465
4bfvZVVPantothenate kinase2.7.1.330.465
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.465
4ycpFMNtRNA-dihydrouridine(16) synthase/0.465
5e5h0T1Succinyl-CoA:acetate CoA-transferase/0.465
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.464
1h60STRPentaerythritol tetranitrate reductase/0.464
1szgFNSCytochrome b2, mitochondrial1.1.2.30.464
1typFADTrypanothione reductase1.8.1.120.464
1wxjIPLTryptophan synthase alpha chain/0.464
2a9y26AAdenosine kinase2.7.1.200.464
2g1s4IGRenin3.4.23.150.464
2g8yNADHydroxycarboxylate dehydrogenase B/0.464
2ozuACOHistone acetyltransferase KAT6A/0.464
3cosNADAlcohol dehydrogenase 41.1.1.10.464
3imgBZ3Pantothenate synthetase6.3.2.10.464
3p80P80Pentaerythritol tetranitrate reductase/0.464
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.464
3vydVYDRenin3.4.23.150.464
4hn1TYDdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.464
1bl4AP1Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.463
1bmdNADMalate dehydrogenase/0.463
1i59ANPChemotaxis protein CheA2.7.13.30.463
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.463
1zw9H64ATP-dependent molecular chaperone HSP82/0.463
2g1y5IGRenin3.4.23.150.463
2g25TDKPyruvate dehydrogenase E1 component1.2.4.10.463
2gvdFKPAdenylate cyclase type 2/0.463
2gvdFKPAdenylate cyclase type 5/0.463
2pobGW4Peroxisome proliferator-activated receptor gamma/0.463
2zr9DTPProtein RecA/0.463
3h3fNAIL-lactate dehydrogenase A chain1.1.1.270.463
3jusBCDLanosterol 14-alpha demethylase1.14.13.700.463
3ld6BCDLanosterol 14-alpha demethylase1.14.13.700.463
3p82FMNPentaerythritol tetranitrate reductase/0.463
4loh1SYStimulator of interferon genes protein/0.463
1akcPPEAspartate aminotransferase, mitochondrial2.6.1.10.462
1icsFMN12-oxophytodienoate reductase 11.3.1.420.462
1psa0ZLPepsin A3.4.23.10.462
1rx8NAPDihydrofolate reductase1.5.1.30.462
1tojHCIAspartate aminotransferase2.6.1.10.462
2cekN8TAcetylcholinesterase3.1.1.70.462
2g1r3IGRenin3.4.23.150.462
3bgsDIHPurine nucleoside phosphorylase2.4.2.10.462
3cwqADPParA family chromosome partitioning protein/0.462
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.462
3t4eNADQuinate/shikimate dehydrogenase/0.462
3tdaPN0Cytochrome P450 2D6/0.462
5einNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.462
1fm4DXCMajor pollen allergen Bet v 1-L/0.461
1ia1NDPDihydrofolate reductase1.5.1.30.461
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.461
2dc1NADProbable L-aspartate dehydrogenase/0.461
2ea2F77Methionine aminopeptidase 2/0.461
2idkC2FGlycine N-methyltransferase2.1.1.200.461
2il2LIXRenin3.4.23.150.461
2iviACWIsopenicillin N synthase1.21.3.10.461
2jk6FADTrypanothione reductase/0.461
2q1tNADPutative nucleotide sugar epimerase/ dehydratase/0.461
3tjzGNPADP-ribosylation factor 1/0.461
3zbzOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.461
4e2bFMNDehydrogenase/0.461
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
4ke11R6Beta-secretase 13.4.23.460.461
4p9dTMPDeoxycytidylate deaminase/0.461
4u7wNDPMxaA/0.461
1adfTADAlcohol dehydrogenase E chain1.1.1.10.460
1p0pBCHCholinesterase3.1.1.80.460
1qpl587Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.460
1xs7MMIBeta-secretase 13.4.23.460.460
1xvaSAMGlycine N-methyltransferase2.1.1.200.460
2b4tAESGlyceraldehyde-3-phosphate dehydrogenase/0.460
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.460
2oc9IMHPurine nucleoside phosphorylase2.4.2.10.460
2pncCLUPrimary amine oxidase, liver isozyme/0.460
3in6FMNUncharacterized protein/0.460
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.460
3pdqKC6Lysine-specific demethylase 4A1.14.110.460
3pfdFDAAcyl-CoA dehydrogenase FadE25/0.460
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.460
4i1iNADMalate dehydrogenase/0.460
4rp8ASCAscorbate-specific PTS system EIIC component/0.460
4ryvZEAProtein LlR18A/0.460
4tmcFMNOld yellow enzyme/0.460
4tyqAP5Adenylate kinase/0.460
4xr9NADCalS8/0.460
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.459
1mxfMTXPutative pteridine reductase 2/0.459
1uxkNADMalate dehydrogenase/0.459
1yqsBSAD-alanyl-D-alanine carboxypeptidase3.4.16.40.459
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.459
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
2znq401Peroxisome proliferator-activated receptor delta/0.459
3b2sB2STrichothecene 3-O-acetyltransferase/0.459
3h3cP1EProtein-tyrosine kinase 2-beta2.7.10.20.459
4cj4S3GIntegrase/0.459
4qxaGTPRas-related protein Rab-9A/0.459
1bil0IURenin3.4.23.150.458
1fxfMJIPhospholipase A2, major isoenzyme3.1.1.40.458
1obbNADAlpha-glucosidase3.2.1.200.458
1rfuADPPyridoxal kinase2.7.1.350.458
2a94AP0L-lactate dehydrogenase1.1.1.270.458
2iyfERYOleandomycin glycosyltransferase2.4.10.458
2oapANPType II secretion system protein (GspE-2)/0.458
2wi5ZZ5Heat shock protein HSP 90-alpha/0.458
3atzFMNProstaglandin F2a synthase/0.458
3b4yF42F420-dependent glucose-6-phosphate dehydrogenase/0.458
3h3sH15Collagen type IV alpha-3-binding protein/0.458
3lqfNADGalactitol dehydrogenase/0.458
3mjrAC2Deoxycytidine kinase2.7.1.740.458
3sqwANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.458
3t3r9PLCytochrome P450 2A61.14.130.458
4a6rTA8Probable aminotransferase/0.458
4drjRAPSerine/threonine-protein kinase mTOR2.7.11.10.458
4drjRAPPeptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.458
4e2wJHZMethyltransferase/0.458
4lzwTHMUridine phosphorylase/0.458
1a8pFADFerredoxin--NADP reductase/0.457
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.457
1me6IVSPlasmepsin-23.4.23.390.457
1rd7FOLDihydrofolate reductase1.5.1.30.457
1t2cNAIL-lactate dehydrogenase1.1.1.270.457
2dvoITTdITP/XTP pyrophosphatase3.6.1.190.457
2vkvTDCTetracycline repressor protein class D/0.457
3phiNDPShikimate dehydrogenase (NADP(+))/0.457
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
3s3vTOPDihydrofolate reductase1.5.1.30.457
3v2uATPProtein GAL3/0.457
4fcr0TMHeat shock protein HSP 90-alpha/0.457
4wdgA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.457
4x7wMVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.457
1eiiRTLRetinol-binding protein 2/0.456
1febFADTrypanothione reductase1.8.1.120.456
1fx9MJIPhospholipase A2, major isoenzyme3.1.1.40.456
1g1aNADdTDP-glucose 4,6-dehydratase/0.456
1h62ANBPentaerythritol tetranitrate reductase/0.456
1lc3NADBiliverdin reductase A1.3.1.240.456
2cftPLPPyridoxal phosphate phosphatase/0.456
2dsgSAHDiphthine synthase/0.456
2ewvADPTwitching motility protein PilT/0.456
2fy4COACholine O-acetyltransferase2.3.1.60.456
2rlcCHDCholoylglycine hydrolase3.5.1.240.456
2v2zADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.456
2zsaADPPantothenate kinase2.7.1.330.456
3af1GDPPantothenate kinase2.7.1.330.456
3juqAJDPhenazine biosynthesis protein A/B/0.456
3m2vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.456
3opxU5PSuppressor of disruption of TFIIS/0.456
3rpeFADPutative modulator of drug activity/0.456
3vswR31Renin3.4.23.150.456
4e2xTYDMethyltransferase/0.456
4fvqATPTyrosine-protein kinase JAK2/0.456
4mr92BXGamma-aminobutyric acid type B receptor subunit 1/0.456
4rww2BALmo2692 protein/0.456
4y35F90Endothiapepsin3.4.23.220.456
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.455
1fkbRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.455
1u1f183Uridine phosphorylase2.4.2.30.455
2b4rAESGlyceraldehyde-3-phosphate dehydrogenase/0.455
2tprFADTrypanothione reductase1.8.1.120.455
3dgqEAAGlutathione S-transferase P2.5.1.180.455
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.455
3o6o94MHeat shock protein 83/0.455
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.455
3p8iFMNPentaerythritol tetranitrate reductase/0.455
3td7FADProbable FAD-linked sulfhydryl oxidase R5961.8.3.20.455
4a81DXCMajor pollen allergen Bet v 1-A/0.455
4bfxZVXPantothenate kinase2.7.1.330.455
4gtv7TRGeranylgeranyl transferase type-2 subunit beta2.5.1.600.455
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.455
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.455
4jtqNAPAldo-keto reductase family 1 member C2/0.455
4k6fNAPPutative Acetoacetyl-CoA reductase/0.455
4mkhAP5Adenylate kinase/0.455
4rnuFMNNADPH dehydrogenase 11.6.99.10.455
4xba5GPAprataxin-like protein30.455
4zwpM44Xaa-Pro dipeptidase3.4.13.90.455
5er0FADUncharacterized NAD(FAD)-dependent dehydrogenase/0.455
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.454
1pq944BOxysterols receptor LXR-beta/0.454
1q45FMN12-oxophytodienoate reductase 31.3.1.420.454
1sq5ADPPantothenate kinase2.7.1.330.454
1udaUFGUDP-glucose 4-epimerase5.1.3.20.454
1x1bSAHC-20 methyltransferase/0.454
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.454
2g21L1BRenin3.4.23.150.454
2ldbNADL-lactate dehydrogenase1.1.1.270.454
2w9hTOPDihydrofolate reductase1.5.1.30.454
3dg8NDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.454
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.454
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.454
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.454
3lzwNAPFerredoxin--NADP reductase 21.18.1.20.454
3o03NAPDehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase)/0.454
3owaFADAcyl-CoA dehydrogenase/0.454
3pl8FADPyranose 2-oxidase/0.454
3sqxANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.454
4bftZVTPantothenate kinase2.7.1.330.454
4bfwZVWPantothenate kinase2.7.1.330.454
4f5dC2EStimulator of interferon genes protein/0.454
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.454
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.454
1ahgTYR_PLPAspartate aminotransferase2.6.1.10.453
1e2nRCAThymidine kinase/0.453
1h22E10Acetylcholinesterase3.1.1.70.453
1qy5NECEndoplasmin/0.453
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
2hs6FMN12-oxophytodienoate reductase 31.3.1.420.453
2hu2NADC-terminal binding protein 1/0.453
2npxNADNADH peroxidase1.11.1.10.453
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.453
2q46NAPUncharacterized protein At5g02240/0.453
2qbuSAHPrecorrin-2 methyltransferase/0.453
2vatCOAAcetyl-CoA--deacetylcephalosporin C acetyltransferase2.3.1.1750.453
3bj8COADiamine acetyltransferase 1/0.453
3bxoUPPdTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose/0.453
3jyqNADQuinate/shikimate dehydrogenase (NAD(+))/0.453
3sp6IL2Peroxisome proliferator-activated receptor alpha/0.453
4ey6GNTAcetylcholinesterase3.1.1.70.453
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.453
5bnw12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.453
1a9zUPGUDP-glucose 4-epimerase5.1.3.20.452
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.452
1rx8FOLDihydrofolate reductase1.5.1.30.452
1stdBFSScytalone dehydratase4.2.1.940.452
2bxfDZPSerum albumin/0.452
2g226IGRenin3.4.23.150.452
2he5NDPAldo-keto reductase family 1 member C211.1.10.452
2hizLIJBeta-secretase 13.4.23.460.452
2qc8ADPGlutamine synthetase6.3.1.20.452
2qo5CHDFatty acid-binding protein 10-A, liver basic/0.452
2rc4ACOHistone acetyltransferase KAT6A/0.452
2stdCRPScytalone dehydratase4.2.1.940.452
2vyqFADFerredoxin--NADP reductase1.18.1.20.452
3c1oNAPEugenol synthase/0.452
3eksCY9Actin-5C/0.452
3lu1UD2UDP-N-acetylglucosamine 4-epimerase/0.452
3own3OXRenin3.4.23.150.452
4ctjSAMGenome polyprotein/0.452
4i1nFOLDihydrofolate reductase1.5.1.30.452
4m4922YL-lactate dehydrogenase A chain1.1.1.270.452
4pzsACOHistone acetyltransferase p300/0.452
4y6uUPGGlucosyl-3-phosphoglycerate synthase2.4.1.2660.452
5cyoGDPSeptin-9/0.452
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.451
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.451
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.451
1rc4DDFDihydrofolate reductase1.5.1.30.451
1rx1NAPDihydrofolate reductase1.5.1.30.451
1rydNDPGlucose--fructose oxidoreductase1.1.99.280.451
2ab8MTPAdenosine kinase2.7.1.200.451
2rghFADAlpha-Glycerophosphate Oxidase/0.451
3enkUPGUDP-glucose 4-epimerase/0.451
3gviADPMalate dehydrogenase/0.451
3p0fBAUUridine phosphorylase 22.4.2.30.451
3uzzTES3-oxo-5-beta-steroid 4-dehydrogenase/0.451
3zeiAWHO-acetylserine sulfhydrylase/0.451
4bk2FADProbable salicylate monooxygenase/0.451
4but31FTankyrase-22.4.2.300.451
4de2DN3Beta-lactamase/0.451
4g74FADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.451
4ha9NDP2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase1.1.1.3020.451
4jiq1L5GTN Reductase/0.451
4k8s1QTBeta-secretase 13.4.23.460.451
4mdhNADMalate dehydrogenase, cytoplasmic1.1.1.370.451
3uonQNBMuscarinic acetylcholine receptor M2/0.451
1esvLARActin, alpha skeletal muscle/0.450
1kw9BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.450
1o6qR17Squalene--hopene cyclase4.2.1.1290.450
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.450
2i4qUA4Renin3.4.23.150.450
2q85973UDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.450
2rds1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.450
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.450
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
3hgoFMN12-oxophytodienoate reductase 31.3.1.420.450
3m2uCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.450
3qfaFADThioredoxin reductase 1, cytoplasmic1.8.1.90.450
3sxjSAMPutative methyltransferase/0.450
3t2vKKJPeptidoglycan recognition protein 1/0.450
3uxvGUNNADPH-dependent 7-cyano-7-deazaguanine reductase/0.450
4e31JHZMethyltransferase/0.450
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.449
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.449
1h2bNAJNAD-dependent alcohol dehydrogenase/0.449
1mj9COAHistone acetyltransferase ESA1/0.449
1npdNADQuinate/shikimate dehydrogenase/0.449
1pqc444Oxysterols receptor LXR-beta/0.449
2abjPLPBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.449
2xfiXFIBeta-secretase 13.4.23.460.449
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.449
3c3xNAPEugenol synthase 11.1.1.3180.449
3fr4F8AFatty acid-binding protein, adipocyte/0.449
3g72A6TRenin3.4.23.150.449
3gqvNAPEnoyl reductase LovC10.449
3nsh957Beta-secretase 13.4.23.460.449
3qj0QI3Botulinum neurotoxin type A3.4.24.690.449
3vyfVYFRenin3.4.23.150.449
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.449
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.449
4el5D1MGlycogen phosphorylase, muscle form2.4.1.10.449
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.449
4i0i957Beta-secretase 13.4.23.460.449
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.449
4kbyC2EStimulator of interferon genes protein/0.449
4lh71X8DNA ligase/0.449
4loi1YCStimulator of interferon genes protein/0.449
4m0f1YKAcetylcholinesterase3.1.1.70.449
5e7oMD1DMSO reductase family type II enzyme, molybdopterin subunit/0.449
5fwnNAPPutative dehydrogenase/0.449
1fwkADPHomoserine kinase2.7.1.390.448
1gveNAPAflatoxin B1 aldehyde reductase member 310.448
1h74AGSHomoserine kinase2.7.1.390.448
1lf2R37Plasmepsin-23.4.23.390.448
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.448
1tqf32PBeta-secretase 13.4.23.460.448
1ur5NADMalate dehydrogenase/0.448
1wuaAP8Actin, alpha skeletal muscle/0.448
2bjfDXCCholoylglycine hydrolase3.5.1.240.448
2e15SAHDiphthine synthase/0.448
2gv8NDPThiol-specific monooxygenase1.14.130.448
2hfuMEVMevalonate kinase/0.448
2p8hMY9Beta-secretase 13.4.23.460.448
2xlpFADPutative flavin-containing monooxygenase/0.448
2z1qFADAcyl-CoA dehydrogenase/0.448
3b1dPLSBetaC-S lyase/0.448
3cukFADD-amino-acid oxidase1.4.3.30.448
3dzkNMNADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.448
3fsjD7KBenzoylformate decarboxylase4.1.1.70.448
3oesGNPGTPase RhebL1/0.448
3pce3HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.448
3pce3HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.448
3qftFADNADPH--cytochrome P450 reductase/0.448
3ty3GGGHomoisocitrate dehydrogenase1.1.1.870.448
4c49HCYCorticosteroid-binding globulin/0.448
4eqkMGTPolymerase basic protein 2/0.448
4fhj0TZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4m6jNDPDihydrofolate reductase1.5.1.30.448
1bim0QBRenin3.4.23.150.447
1k7l544Peroxisome proliferator-activated receptor alpha/0.447
1kh3ANPArgininosuccinate synthase/0.447
1kqwRTLCellular retinol-binding protein type II/0.447
1tehNADAlcohol dehydrogenase class-31.1.1.10.447
1yw8A75Methionine aminopeptidase 2/0.447
1zp4FAD5,10-methylenetetrahydrofolate reductase1.5.1.200.447
2bu9HFVIsopenicillin N synthase1.21.3.10.447
2bxqIMNSerum albumin/0.447
2ejvNADL-threonine 3-dehydrogenase/0.447
2f3rG5PGuanylate kinase2.7.4.80.447
2fdpFRPBeta-secretase 13.4.23.460.447
2hk9NAPShikimate dehydrogenase (NADP(+))/0.447
2vizVG4Beta-secretase 13.4.23.460.447
2whqHI6Acetylcholinesterase3.1.1.70.447
3br3ETHTH-type transcriptional regulator QacR/0.447
3dufR1TPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.447
3dufR1TPyruvate dehydrogenase E1 component subunit beta1.2.4.10.447
3ixj586Beta-secretase 13.4.23.460.447
3kruFMNNADH:flavin oxidoreductase/NADH oxidase/0.447
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.447
4f5yC2EStimulator of interferon genes protein/0.447
4f9gC2EStimulator of interferon genes protein/0.447
4hmvWUBPhenazine biosynthesis protein PhzG1.40.447
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.447
5c1gGDUHisto-blood group ABO system transferase/0.447
1fmlRTLRetinol dehydratase/0.446
1gw2FERPeroxidase C1A1.11.1.70.446
1ooqFMNOxygen-insensitive NAD(P)H nitroreductase/0.446
2cndFADNitrate reductase [NADH]1.7.1.10.446
2ea4F79Methionine aminopeptidase 2/0.446
2g0bNLTLong-chain N-acyl amino acid synthase/0.446
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.446
2ohvNHLGlutamate racemase/0.446
2vkmBSDBeta-secretase 13.4.23.460.446
3d84NDPDihydrofolate reductase1.5.1.30.446
3fhxPXLPyridoxal kinase2.7.1.350.446
3gf4UPGUDP-galactopyranose mutase5.4.99.90.446
3iu8T03Methionine aminopeptidase 2/0.446
3rn8RN8Glutamate receptor 2/0.446
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.446
4hbgNDP3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.446
4tqgNDPPutative dTDP-d-glucose 4 6-dehydratase/0.446
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
5hwoHMGHydroxymethylglutaryl-CoA synthase/0.446
1ja0FADNADPH--cytochrome P450 reductase/0.445
1y6oMJIPhospholipase A2, major isoenzyme3.1.1.40.445
2b8v3BNBeta-secretase 13.4.23.460.445
2fvlNAPAldo-keto reductase family 1 member C41.1.1.2250.445
2pamTYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.445
2rhgIGPTryptophan synthase alpha chain/0.445
2xpc051UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.445
3bnkFMNFlavoredoxin/0.445
3c27DKKProthrombin3.4.21.50.445
3cavCI23-oxo-5-beta-steroid 4-dehydrogenase/0.445
3fr5I4AFatty acid-binding protein, adipocyte/0.445
3gvhNADMalate dehydrogenase/0.445
3hy7097A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.445
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3phjDHKShikimate dehydrogenase (NADP(+))/0.445
3qpg3QPAspartate aminotransferase2.6.1.10.445
3toh079Gag-Pol polyprotein2.7.7.490.445
3w6hAZMCarbonic anhydrase 14.2.1.10.445
3w77FMNFMN-dependent NADH-azoreductase/0.445
3whaWHAHeat shock protein HSP 90-alpha/0.445
3zt3ZT4Integrase/0.445
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.445
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.445
4i13FOLDihydrofolate reductase1.5.1.30.445
4xbaGMPAprataxin-like protein30.445
1mbbEEBUDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.444
1msmJE2Gag-Pol polyprotein3.4.23.160.444
1nzfUPGDNA beta-glucosyltransferase/0.444
1qxoFMNChorismate synthase/0.444
1vi2NADQuinate/shikimate dehydrogenase/0.444
1yw7A41Methionine aminopeptidase 2/0.444
2abaSTRPentaerythritol tetranitrate reductase/0.444
2b0qADPAminoglycoside 3'-phosphotransferase2.7.1.950.444
2bb3SAHCobalamin biosynthesis precorrin-6Y methylase (CbiE)/0.444
2fj1CTCTetracycline repressor protein class D/0.444
2g263LGRenin3.4.23.150.444
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.444
2hxzH7JCathepsin S3.4.22.270.444
2jgsBTNAvidin/0.444
2jkvNAP6-phosphogluconate dehydrogenase, decarboxylating1.1.1.440.444
2onmADPAldehyde dehydrogenase, mitochondrial1.2.1.30.444
2r2mI50Prothrombin3.4.21.50.444
2zs8ADPPantothenate kinase2.7.1.330.444
3atyFMNProstaglandin F2a synthase/0.444
3b70NAPEnoyl reductase LovC10.444
3cic316Beta-secretase 13.4.23.460.444
3e8xNAPBH1520 protein/0.444
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.444
3fapARDPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.444
3fapARDSerine/threonine-protein kinase mTOR2.7.11.10.444
3fazNOSPurine nucleoside phosphorylase/0.444
3gwdNAPCyclohexanone monooxygenase/0.444
3i0aDBHNeutrophil gelatinase-associated lipocalin/0.444
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3ou2SAHSAM-dependent methyltransferase/0.444
3pftFMNFlavin reductase/0.444
3ppr4CSGlycine betaine/carnitine/choline-binding protein OpuCC/0.444
3s87ADPRibonucleoside-diphosphate reductase large chain 11.17.4.10.444
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.444
3stdMQ0Scytalone dehydratase4.2.1.940.444
3u57DH8Raucaffricine-O-beta-D-glucosidase3.2.1.1250.444
3v0o4GWHisto-blood group ABO system transferase/0.444
4a99FADTetX family tetracycline inactivation enzyme/0.444
4an4DUDPutative glycosyl transferase/0.444
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4brgGNPEctonucleoside triphosphate diphosphohydrolase I/0.444
4e2dFMNDehydrogenase/0.444
4fse0VABeta-secretase 13.4.23.460.444
4giu636Anthranilate phosphoribosyltransferase/0.444
4gukP2GNeuronal calcium sensor 1/0.444
4k28NADShikimate dehydrogenase family protein/0.444
4lhtCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.444
4lnbED5CaaX farnesyltransferase beta subunit Ram1/0.444
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.444
4v2gITCTetracycline repressor protein class D/0.444
4wdfA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.444
1guyNADMalate dehydrogenase/0.443
1obnASVIsopenicillin N synthase1.21.3.10.443
1og4NAIT-cell ecto-ADP-ribosyltransferase 2/0.443
1rftPXMPyridoxal kinase2.7.1.350.443
1rkwPNTHTH-type transcriptional regulator QacR/0.443
1rzuADPGlycogen synthase 12.4.1.210.443
1umkFADNADH-cytochrome b5 reductase 31.6.2.20.443
1zp3FAD5,10-methylenetetrahydrofolate reductase1.5.1.200.443
1zrqFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.443
2c29NAPDihydroflavonol 4-reductase/0.443
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
2op18PCEnoyl-ACP reductase/0.443
3ai3NDPNADPH-sorbose reductase/0.443
3dvaTPWPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.443
3dvaTPWPyruvate dehydrogenase E1 component subunit beta1.2.4.10.443
3fr28CAFatty acid-binding protein, adipocyte/0.443
3hlwCE3Beta-lactamase/0.443
3rykTYDdTDP-4-dehydrorhamnose 3,5-epimerase/0.443
3t88S0N1,4-dihydroxy-2-naphthoyl-CoA synthase/0.443
3tozNADShikimate dehydrogenase (NADP(+))/0.443
4bb3KKAIsopenicillin N synthase1.21.3.10.443
4gllNADUDP-glucuronic acid decarboxylase 14.1.1.350.443
4jayNAPUDP-N-acetylenolpyruvoylglucosamine reductase/0.443
4jsr1NQNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.443
4pnrG18Tankyrase-22.4.2.300.443
4rrrA3TThreonine--tRNA ligase6.1.1.30.443
4tlzFADKtzI/0.443
9gssGTXGlutathione S-transferase P2.5.1.180.443
1galFADGlucose oxidase1.1.3.40.442
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.442
1r5hAO2Methionine aminopeptidase 2/0.442
1rkhVD2Vitamin D3 receptor/0.442
1tl7FOKAdenylate cyclase type 2/0.442
1tl7FOKAdenylate cyclase type 5/0.442
1zdwFLVPrenyltransferase/0.442
2a9z26AAdenosine kinase2.7.1.200.442
2anb5GPGuanylate kinase2.7.4.80.442
2dv4SAHDiphthine synthase/0.442
2ev9NAPShikimate dehydrogenase (NADP(+))/0.442
2fonFADAcyl-coenzyme A oxidase/0.442
2fr1NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.442
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.442
2iypNAP6-phosphogluconate dehydrogenase, decarboxylating1.1.1.440.442
2r2lPB9Protein farnesyltransferase subunit beta2.5.1.580.442
2rcyNAPPyrroline-5-carboxylate reductase/0.442
2vwqNAPGlucose 1-dehydrogenase/0.442
3h2sNDPPutative NADH-flavin reductase/0.442
3ha3SAHHydroxymycolate synthase MmaA42.1.10.442
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.442
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.442
3px3T3QdTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase2.1.1.2350.442
3rlr3RRHeat shock protein HSP 90-alpha/0.442
3to3ATPPetrobactin biosynthesis protein AsbB/0.442
3tr05GPGuanylate kinase/0.442
3up5FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.442
3zhyFM61-deoxy-D-xylulose 5-phosphate reductoisomerase/0.442
3zvmADPBifunctional polynucleotide phosphatase/kinase2.7.1.780.442
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.442
4j4nD44Peptidylprolyl isomerase/0.442
4jxxATPGlutamine--tRNA ligase6.1.1.180.442
4oqyNDP(S)-imine reductase/0.442
4oztP1AEcdysone receptor, putative/0.442
4rnwFMNNADPH dehydrogenase 11.6.99.10.442
4tjy3GNTankyrase-22.4.2.300.442
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.442
4yp12BAStimulator of interferon genes protein/0.442
1e81M91Endothiapepsin3.4.23.220.441
1gpeFADGlucose oxidase1.1.3.40.441
1h6cNDPGlucose--fructose oxidoreductase1.1.99.280.441
1ikgREXD-alanyl-D-alanine carboxypeptidase3.4.16.40.441
1ju9NADAlcohol dehydrogenase E chain1.1.1.10.441
1kw0H4BPhenylalanine-4-hydroxylase1.14.16.10.441
1t7o152Carnitine O-acetyltransferase2.3.1.70.441
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.441
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.441
2bl4NADLactaldehyde reductase1.1.1.770.441
2c12FADNitroalkane oxidase1.7.3.10.441
2e7zMGDAcetylene hydratase/0.441
2eleSAHDiphthine synthase/0.441
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.441
2iqgF2IBeta-secretase 13.4.23.460.441
2oazI96Methionine aminopeptidase 2/0.441
2wu4HBPAcetylcholinesterase3.1.1.70.441
2x8hFADThioredoxin glutathione reductase/0.441
2xhrC0PHeat shock protein HSP 90-alpha/0.441
2xugTZ4Acetylcholinesterase3.1.1.70.441
2xuiTZ5Acetylcholinesterase3.1.1.70.441
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.441
3dszLIZNeutrophil gelatinase-associated lipocalin/0.441
3ei8PL5LL-diaminopimelate aminotransferase, chloroplastic/0.441
3gjwGJWPoly [ADP-ribose] polymerase 12.4.2.300.441
3h86AP5Adenylate kinase/0.441
3q43D66M1 family aminopeptidase3.4.110.441
3t7x4SHEndothiapepsin3.4.23.220.441
3tqxPLP2-amino-3-ketobutyrate coenzyme A ligase/0.441
3tydXHPDihydropteroate synthase/0.441
3vilSA0Beta-glucosidase/0.441
3wycNAPMeso-diaminopimelate D-dehydrogenase1.4.1.160.441
4a3uFMNNADH:flavin oxidoreductase/NADH oxidase/0.441
4c1eMCOBeta-lactamase class B VIM-2/0.441
4cfaWOPIntegrase/0.441
4e32DWNMethyltransferase/0.441
4ef9FMNDihydroorotate dehydrogenase (fumarate)/0.441
4hyvPEPPyruvate kinase 12.7.1.400.441
4i8x6P3L-lactate dehydrogenase A chain1.1.1.270.441
4isg1FYGlucokinase2.7.1.20.441
4prxADPDNA gyrase subunit B/0.441
4rr7A3SProbable threonine--tRNA ligase 26.1.1.30.441
4tuvCPZCytochrome P450 1191.140.441
4y57F63Endothiapepsin3.4.23.220.441
1ebdFADDihydrolipoyl dehydrogenase1.8.1.40.440
1g4tFTPThiamine-phosphate synthase/0.440
1i24UPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.440
1kt8ILPBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.440
1lf3EH5Plasmepsin-23.4.23.390.440
1nqw5YL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.440
1rdwLARActin, alpha skeletal muscle/0.440
1rz0FADPhenol 2-hydroxylase component B/0.440
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.440
2jb4A14Isopenicillin N synthase1.21.3.10.440
2p5uNADUDP-glucose 4-epimerase/0.440
2wzwNDPNitroreductase NfnB/0.440
2xupTZ5Acetylcholinesterase3.1.1.70.440
2yj4ATPCopper-transporting ATPase/0.440
2ym2FADPhenylacetone monooxygenase1.14.13.920.440
2z3lPHE_ARG_TYR_LEU_GLYLeucyl/phenylalanyl-tRNA--protein transferase2.3.2.60.440
3fp0FP015-O-acetyltransferase/0.440
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.440
3mvm39PMitogen-activated protein kinase 14/0.440
3smkCW714-3-3 protein sigma/0.440
3tfuPL8Adenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.440
3vdqNAD3-hydroxybutyrate dehydrogenase/0.440
4elf35IDihydrofolate reductase/0.440
4ho4THMGlucose-1-phosphate thymidylyltransferase/0.440
4i521HA1,4-dihydroxy-2-naphthoyl-CoA synthase/0.440
4iacACPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
4ipw1G7Mycocyclosin synthase1.14.21.90.440
4layI63Peptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.440
4ockANPN-acetylhexosamine 1-kinase2.7.1.1620.440
4rrhA3SProbable threonine--tRNA ligase 26.1.1.30.440
4x7uZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.440