sc-PDB

List of CHEMBLId :

This value allows a number of roughly comparable measures of half-maximal response concentration/potency/affinity to be compared on a negative logarithmic scale (e.g., an IC50 measurement of 1nM would have a pChEMBL value of 9).

Uniprot Annotation

Name:	Glutamate receptor 2
ID:	GRIA2_HUMAN
AC:	P42262
Organism:	Homo sapiens
Reign:	Eukaryota
TaxID:	9606
EC Number:	/

---

Chains:

Chain Name:	Percentage of Residues within binding site
A	50 %
C	50 %

---

Ligand binding site composition:

B-Factor:	18.055
Number of residues:	39
Including
Standard Amino Acids:	36
Non Standard Amino Acids:	0
Water Molecules:	3
Cofactors:
Metals:

---

Cavity properties

Ligandability	Volume (Å3)
0.842	425.250

% Hydrophobic	% Polar
36.51	63.49
According to VolSite

HET Code:	RN8
Formula:	C22H14N2O4S2
Molecular weight:	434.488 g/mol
DrugBank ID:	-
Buried Surface Area:	65.74 %
Polar Surface area:	184.32 Å2

Number of
H-Bond Acceptors:	6
H-Bond Donors:	0
Rings:	3
Aromatic rings:	3
Anionic atoms:	2
Cationic atoms:	0
Rule of Five Violation:	0
Rotatable Bonds:	6

---

Mass center Coordinates

X	Y	Z
61.1059	26.2088	43.1824

• 2D View
• 3D View