sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3ojg | HL4 | Phosphotriesterase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3ojg | HL4 | Phosphotriesterase | / | 1.000 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.584 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.550 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.544 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.537 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.523 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.519 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.519 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.518 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.516 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.514 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.513 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.510 | |
| 3djl | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.510 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.509 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.509 | |
| 4h7c | 10H | Aldo-keto reductase family 1 member C3 | / | 0.509 | |
| 1thz | 326 | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.508 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.505 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.505 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.503 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.503 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.503 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.503 | |
| 3o57 | ZG2 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.502 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.501 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.501 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.500 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.499 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.498 | |
| 4nqg | CZH | Mitrocomin | / | 0.496 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.495 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.494 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.494 | |
| 1zdw | FLV | Prenyltransferase | / | 0.494 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.494 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.494 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.494 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.493 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.492 | |
| 1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.491 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.491 | |
| 4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.491 | |
| 4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.491 | |
| 1el4 | CTZ | Obelin | / | 0.490 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.490 | |
| 3o76 | GTB | Glutathione S-transferase P 1 | 2.5.1.18 | 0.489 | |
| 3up3 | XCA | aceDAF-12 | / | 0.489 | |
| 4dlc | UMP | Deoxyuridine triphosphatase, putative | / | 0.489 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.489 | |
| 5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.489 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.488 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.488 | |
| 2x9g | LYA | Pteridine reductase | / | 0.488 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.488 | |
| 1rxj | BNI | Streptavidin | / | 0.487 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.487 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.487 | |
| 3arv | SAU | Chitinase A | / | 0.487 | |
| 3nyt | ULP | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.487 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.486 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.486 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.485 | |
| 2ckm | AA7 | Acetylcholinesterase | 3.1.1.7 | 0.485 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.485 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.485 | |
| 4kfj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.485 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.484 | |
| 2cbq | TH2 | Neocarzinostatin | / | 0.484 | |
| 2fje | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.484 | |
| 2nn7 | M29 | Carbonic anhydrase 1 | 4.2.1.1 | 0.484 | |
| 2wd8 | VGF | Pteridine reductase | / | 0.484 | |
| 3eon | 341 | Glutaryl-CoA dehydrogenase | / | 0.484 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.484 | |
| 3zhu | TD8 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.484 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.484 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.484 | |
| 1ml6 | GBX | Glutathione S-transferase A2 | 2.5.1.18 | 0.483 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.483 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.483 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.483 | |
| 3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.483 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.482 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.482 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.482 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.482 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.482 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.481 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.481 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.481 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.481 | |
| 3jqg | AX6 | Pteridine reductase, putative | / | 0.481 | |
| 3zhv | TDW | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.481 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.481 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.481 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.481 | |
| 1ej3 | CZH | Aequorin-2 | / | 0.480 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.480 | |
| 2fja | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.480 | |
| 2x9v | TMQ | Pteridine reductase | / | 0.480 | |
| 3g4l | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.480 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.480 | |
| 3p0e | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.480 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.480 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.480 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.480 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.480 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.480 | |
| 4iji | 99T | Glutathione S-transferase-like protein YibF | / | 0.480 | |
| 1dpm | EBP | Parathion hydrolase | 3.1.8.1 | 0.479 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.479 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.479 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.479 | |
| 1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.478 | |
| 1qv1 | CZH | Obelin | / | 0.478 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.478 | |
| 2cje | DUN | DUTPase | / | 0.478 | |
| 2fb3 | 5AD | GTP 3',8-cyclase | 4.1.99.18 | 0.478 | |
| 2in6 | 839 | Wee1-like protein kinase | 2.7.10.2 | 0.478 | |
| 1o6r | R19 | Squalene--hopene cyclase | 4.2.1.129 | 0.477 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.477 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.477 | |
| 2xtb | KRM | Adenosine kinase, putative | / | 0.477 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.477 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.477 | |
| 3r94 | FLR | Aldo-keto reductase family 1 member C3 | / | 0.477 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.477 | |
| 4e2y | JHZ | Methyltransferase | / | 0.477 | |
| 4n1f | CZH | Obelin | / | 0.477 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 1syn | F89 | Thymidylate synthase | / | 0.476 | |
| 2aj4 | ANP | Galactokinase | 2.7.1.6 | 0.476 | |
| 2dg9 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.476 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.476 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.476 | |
| 3n0y | APC | Adenylate cyclase 2 | / | 0.476 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.476 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.476 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.476 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.475 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.475 | |
| 4az3 | S35 | Lysosomal protective protein | 3.4.16.5 | 0.475 | |
| 4b6u | M7G | Eukaryotic translation initiation factor 4E type 3 | / | 0.475 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.475 | |
| 4boe | CLR | Japanin | / | 0.475 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.475 | |
| 4iwv | 1J9 | Glucokinase | 2.7.1.2 | 0.475 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.474 | |
| 1mxf | MTX | Putative pteridine reductase 2 | / | 0.474 | |
| 1v08 | NTZ | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.474 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.474 | |
| 2rds | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.474 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.474 | |
| 4dsb | A8S | Abscisic acid receptor PYL3 | / | 0.474 | |
| 4lb2 | DM5 | Serum albumin | / | 0.474 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.473 | |
| 1rvv | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.473 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.473 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.473 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.473 | |
| 4fj2 | QSO | 17beta-hydroxysteroid dehydrogenase | / | 0.473 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.472 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.472 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.472 | |
| 3occ | DIH | Purine nucleoside phosphorylase DeoD-type | / | 0.472 | |
| 3qwi | CUE | 17beta-hydroxysteroid dehydrogenase | / | 0.472 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.472 | |
| 4bfs | ZVS | Pantothenate kinase | 2.7.1.33 | 0.472 | |
| 4kc4 | WS3 | Histo-blood group ABO system transferase | / | 0.472 | |
| 4phl | PIL | Phosphodiesterase | / | 0.472 | |
| 1e2n | RCA | Thymidine kinase | / | 0.471 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.471 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.471 | |
| 1qv0 | CZH | Obelin | / | 0.471 | |
| 1ve3 | SAM | Uncharacterized protein | / | 0.471 | |
| 2c7q | SAH | Modification methylase HhaI | 2.1.1.37 | 0.471 | |
| 2c9d | PHR | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.471 | |
| 2fxu | BID | Actin, alpha skeletal muscle | / | 0.471 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.471 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.471 | |
| 3eej | 53R | Uncharacterized protein | / | 0.471 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.471 | |
| 3r8g | IZP | Aldo-keto reductase family 1 member C3 | / | 0.471 | |
| 1dls | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 1std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.470 | |
| 2b3v | ACO | Diamine acetyltransferase 1 | / | 0.470 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.470 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.470 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.470 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.470 | |
| 1kyz | FER | Caffeic acid 3-O-methyltransferase | 2.1.1.68 | 0.469 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.469 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.469 | |
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.469 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.469 | |
| 3ogk | OGK | Coronatine-insensitive protein 1 | / | 0.469 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.469 | |
| 3zhs | TD6 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.469 | |
| 4ixd | 1HV | Integrin alpha-L | / | 0.469 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.469 | |
| 1nqx | RLP | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.468 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.468 | |
| 2fxf | ACO | Diamine acetyltransferase 1 | / | 0.468 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.468 | |
| 3hgg | CHD | CmeR | / | 0.468 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.468 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.468 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.467 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.467 | |
| 1zua | TOL | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.467 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.467 | |
| 3nzp | PLP | Arginine decarboxylase | / | 0.467 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.467 | |
| 4dbu | BT9 | Aldo-keto reductase family 1 member C3 | / | 0.467 | |
| 4iae | 1DX | Alr2278 protein | / | 0.467 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.466 | |
| 1qsn | COA | HAT A1 | / | 0.466 | |
| 1uhh | CZP | Aequorin-2 | / | 0.466 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 2on6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.466 | |
| 3af3 | GCP | Pantothenate kinase | 2.7.1.33 | 0.466 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.466 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.466 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.465 | |
| 1y6o | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.465 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.465 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.465 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.465 | |
| 3l05 | SN0 | N-acetylornithine carbamoyltransferase | 2.1.3.9 | 0.465 | |
| 3zsh | 469 | Mitogen-activated protein kinase 14 | / | 0.465 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.465 | |
| 4ia0 | 5BB | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.465 | |
| 4rh1 | 0TT | Spore photoproduct lyase | / | 0.465 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.464 | |
| 1r8q | AFB | Cytohesin-2 | / | 0.464 | |
| 1r8q | AFB | ADP-ribosylation factor 1 | / | 0.464 | |
| 1w19 | T1P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.464 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.464 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.464 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.464 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.464 | |
| 3mla | JJZ | Probable nicotinate-nucleotide adenylyltransferase | / | 0.464 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.464 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.464 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.464 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.464 | |
| 4jq2 | SUZ | Aldo-keto reductase family 1 member C2 | / | 0.464 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.464 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.463 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.463 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.463 | |
| 2gqg | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.463 | |
| 2hct | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.463 | |
| 2pdl | TOL | Aldose reductase | 1.1.1.21 | 0.463 | |
| 2yhu | WHF | Pteridine reductase | / | 0.463 | |
| 2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.463 | |
| 3fko | FKO | Mitogen-activated protein kinase 14 | / | 0.463 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.463 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.463 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.463 | |
| 3pz2 | 3PZ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.463 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.463 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.463 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.463 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.463 | |
| 4yp6 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.463 | |
| 4zgs | NAD | Putative D-lactate dehydrogenase | / | 0.463 | |
| 1akc | PPE | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.462 | |
| 1dgh | NDP | Catalase | 1.11.1.6 | 0.462 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.462 | |
| 1l8q | ADP | Chromosomal replication initiator protein DnaA | / | 0.462 | |
| 1t90 | NAD | Malonate-semialdehyde dehydrogenase | 1.2.1.27 | 0.462 | |
| 2vrb | NAP | Triphenylmethane reductase | / | 0.462 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.462 | |
| 2zsd | COA | Pantothenate kinase | 2.7.1.33 | 0.462 | |
| 3eem | 53V | Uncharacterized protein | / | 0.462 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 3keq | NAD | Redox-sensing transcriptional repressor Rex | / | 0.462 | |
| 3myt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.462 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.462 | |
| 3sl6 | JN8 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.462 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.462 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.462 | |
| 4azw | ATP | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.462 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.462 | |
| 4ehy | ADP | Tetraacyldisaccharide 4'-kinase | / | 0.462 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.462 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.462 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.462 | |
| 4x81 | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.462 | |
| 5bt4 | 2LO | Bromodomain-containing protein 4 | / | 0.462 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.461 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.461 | |
| 1nbm | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.461 | |
| 1r5h | AO2 | Methionine aminopeptidase 2 | / | 0.461 | |
| 1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.461 | |
| 2b82 | ADN | Class B acid phosphatase | 3.1.3.2 | 0.461 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.461 | |
| 2pl0 | STI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.461 | |
| 2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.461 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.461 | |
| 3vg9 | ZMA | Adenosine receptor A2a | / | 0.461 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.461 | |
| 4kc1 | WS1 | Histo-blood group ABO system transferase | / | 0.461 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.461 | |
| 1fml | RTL | Retinol dehydratase | / | 0.460 | |
| 1l2t | ATP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.460 | |
| 1xdk | REA | Retinoic acid receptor beta | / | 0.460 | |
| 2avx | HTF | Regulatory protein SdiA | / | 0.460 | |
| 2vi5 | Y19 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.460 | |
| 3cas | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.460 | |
| 3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.460 | |
| 3p9t | TCL | Repressor | / | 0.460 | |
| 3uyk | 0CX | Probable NDP-rhamnosyltransferase | / | 0.460 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.460 | |
| 4fa3 | 0SL | Aldo-keto reductase family 1 member C3 | / | 0.460 | |
| 4gtv | 7TR | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.460 | |
| 4n82 | FMN | Ribonucleotide reductase (NrdI family protein), putative | / | 0.460 | |
| 5hwp | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.460 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.460 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.459 | |
| 1y6r | MTM | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | 3.2.2.9 | 0.459 | |
| 2xkf | BX1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.459 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.459 | |
| 3n19 | FNR | Xenobiotic reductase | / | 0.459 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 3sl8 | JN7 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.459 | |
| 3wtk | TH4 | Acetylcholine-binding protein | / | 0.459 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.459 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.459 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.459 | |
| 4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.459 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.459 | |
| 1jra | FAD | FAD-linked sulfhydryl oxidase ERV2 | 1.8.3.2 | 0.458 | |
| 1kwc | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.458 | |
| 1lke | DOG | Bilin-binding protein | / | 0.458 | |
| 1nzy | BCA | 4-chlorobenzoyl coenzyme A dehalogenase | 3.8.1.7 | 0.458 | |
| 1pl6 | 572 | Sorbitol dehydrogenase | 1.1.1.14 | 0.458 | |
| 1rp4 | FAD | Endoplasmic oxidoreductin-1 | 1.8.4 | 0.458 | |
| 1rq1 | FAD | Endoplasmic oxidoreductin-1 | 1.8.4 | 0.458 | |
| 1vkg | CRI | Histone deacetylase 8 | 3.5.1.98 | 0.458 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.458 | |
| 2e48 | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.458 | |
| 2g8n | F83 | Phenylethanolamine N-methyltransferase | 2.1.1.28 | 0.458 | |
| 2get | COK | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.458 | |
| 3ezp | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.458 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.458 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.458 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.458 | |
| 3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.458 | |
| 3nxr | D2D | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 3rba | COD | Phosphopantetheine adenylyltransferase | / | 0.458 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.458 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.458 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.458 | |
| 4wev | SUZ | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.458 | |
| 4xbj | IN5 | Alanine racemase, biosynthetic | / | 0.458 | |
| 1c7o | PPG | Hemolysin | / | 0.457 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 1jf2 | CZH | Obelin | / | 0.457 | |
| 1o2e | ANN | Phospholipase A2 | 3.1.1.4 | 0.457 | |
| 1ycg | FMN | Nitric oxide reductase | 1 | 0.457 | |
| 2bf4 | FMN | NADPH--cytochrome P450 reductase | / | 0.457 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.457 | |
| 2d06 | EST | Sulfotransferase 1A1 | 2.8.2.1 | 0.457 | |
| 2xyt | TC9 | Soluble acetylcholine receptor | / | 0.457 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3r58 | NPS | Aldo-keto reductase family 1 member C3 | / | 0.457 | |
| 4ajg | F07 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.457 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.457 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.457 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.457 | |
| 4fj0 | HHF | 17beta-hydroxysteroid dehydrogenase | / | 0.457 | |
| 4hmn | 16J | Aldo-keto reductase family 1 member C3 | / | 0.457 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.457 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.457 | |
| 1g8o | U5P | N-acetyllactosaminide alpha-1,3-galactosyltransferase | / | 0.456 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.456 | |
| 2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.456 | |
| 2flh | ZEA | Cytokinin-specific binding protein | / | 0.456 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.456 | |
| 2jj8 | AZZ | Deoxynucleoside kinase | / | 0.456 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.456 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 2vqo | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.456 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.456 | |
| 3ntz | 3TZ | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
| 3zia | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.456 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.456 | |
| 4drn | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.456 | |
| 4jsr | 1NQ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.456 | |
| 4zzj | CNA | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.456 | |
| 1al8 | DHP | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.455 | |
| 1n3s | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.455 | |
| 1rkw | PNT | HTH-type transcriptional regulator QacR | / | 0.455 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.455 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 2bn4 | FAD | NADPH--cytochrome P450 reductase | / | 0.455 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.455 | |
| 2h44 | 7CA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.455 | |
| 2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.455 | |
| 3l06 | SN0 | N-acetylornithine carbamoyltransferase | 2.1.3.9 | 0.455 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.455 | |
| 3mp3 | HGG | Hydroxymethylglutaryl-CoA lyase, mitochondrial | 4.1.3.4 | 0.455 | |
| 3pn1 | IVH | DNA ligase | / | 0.455 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.455 | |
| 3seq | NXX | Glutamine-dependent NAD(+) synthetase | 6.3.5.1 | 0.455 | |
| 3zht | TD9 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.455 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.455 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.455 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.455 | |
| 4gn6 | TYL | Lactoperoxidase | 1.11.1.7 | 0.455 | |
| 4i9z | 5BA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.455 | |
| 4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.455 | |
| 4oex | 5EO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.455 | |
| 5d1b | TSN | Histone deacetylase 8 | 3.5.1.98 | 0.455 | |
| 5mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.455 | |
| 7dfr | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 4u15 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.455 | |
| 1n5v | NOM | ActVA 6 protein | / | 0.454 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.454 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.454 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.454 | |
| 2aou | CQA | Histamine N-methyltransferase | 2.1.1.8 | 0.454 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 2jiz | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.454 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.454 | |
| 3acy | 702 | Dehydrosqualene synthase | / | 0.454 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.454 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.454 | |
| 4c1f | X8Z | Metallo-beta-lactamase type 2 | / | 0.454 | |
| 4ej1 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.454 | |
| 4gd9 | BTN | Streptavidin | / | 0.454 | |
| 4jt9 | 1NS | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.454 | |
| 4kfq | KFQ | Glutamate receptor ionotropic, NMDA 1 | / | 0.454 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.454 | |
| 4o9c | COA | Acetyl-CoA acetyltransferase | 2.3.1.9 | 0.454 | |
| 4oma | LCS | Methionine gamma-lyase | / | 0.454 | |
| 1hfr | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1kyy | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.453 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.453 | |
| 1n71 | COA | Aac(6')-Ii protein | / | 0.453 | |
| 1ogx | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.453 | |
| 1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.453 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 3clx | X22 | E3 ubiquitin-protein ligase XIAP | 6.3.2 | 0.453 | |
| 3e6e | DCS | Alanine racemase | / | 0.453 | |
| 3nn6 | HNK | 6-hydroxy-L-nicotine oxidase | / | 0.453 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.453 | |
| 3pz3 | PZ3 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.453 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.453 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 4ddr | MMV | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 4eft | EFT | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 4mv3 | ACP | Biotin carboxylase | 6.3.4.14 | 0.453 | |
| 4n1g | CEI | Obelin | / | 0.453 | |
| 4trj | 665 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.453 | |
| 4x7w | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.453 | |
| 4yjd | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.453 | |
| 1jf0 | CZH | Obelin | / | 0.452 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.452 | |
| 2b0q | ADP | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.452 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.452 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.452 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.452 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.452 | |
| 2std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.452 | |
| 2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.452 | |
| 2xwe | AMF | Glucosylceramidase | 3.2.1.45 | 0.452 | |
| 3c1o | NAP | Eugenol synthase | / | 0.452 | |
| 3g72 | A6T | Renin | 3.4.23.15 | 0.452 | |
| 3hwx | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.452 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.452 | |
| 3v35 | NTI | Aldose reductase | 1.1.1.21 | 0.452 | |
| 3vjc | ZGA | Squalene synthase | 2.5.1.21 | 0.452 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 4gtt | 7TQ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.452 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.452 | |
| 4m48 | 21B | Sodium-dependent dopamine transporter | / | 0.452 | |
| 4xoq | F42 | Coenzyme F420:L-glutamate ligase | / | 0.452 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1kmv | LII | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.451 | |
| 1odj | GMP | Purine nucleoside phosphorylase | / | 0.451 | |
| 1pz1 | NAP | General stress protein 69 | / | 0.451 | |
| 1s36 | CEI | Obelin | / | 0.451 | |
| 1skm | SAH | Modification methylase HhaI | 2.1.1.37 | 0.451 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 2ohh | FMN | Type A flavoprotein FprA | 1 | 0.451 | |
| 2p1t | 3TN | Retinoic acid receptor RXR-alpha | / | 0.451 | |
| 2pam | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.451 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.451 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.451 | |
| 3fnh | JPJ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 3hyw | DCQ | Sulfide-quinone reductase | / | 0.451 | |
| 3jq7 | DX2 | Pteridine reductase, putative | / | 0.451 | |
| 3s41 | S41 | Glucokinase | 2.7.1.2 | 0.451 | |
| 3tfn | 2CJ | Dehydrosqualene synthase | / | 0.451 | |
| 4dk7 | 0KS | Oxysterols receptor LXR-beta | / | 0.451 | |
| 4jtr | IBP | Aldo-keto reductase family 1 member C2 | / | 0.451 | |
| 4nbi | D3Y | D-tyrosyl-tRNA(Tyr) deacylase | / | 0.451 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.451 | |
| 4y17 | LAE | Transcriptional regulator of ftsQAZ gene cluster | / | 0.451 | |
| 1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.450 | |
| 2c42 | TPP | Pyruvate synthase | / | 0.450 | |
| 2g0g | SP0 | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.450 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.450 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.450 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.450 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.450 | |
| 3i5x | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.450 | |
| 3ix8 | TX3 | Transcriptional activator protein LasR | / | 0.450 | |
| 3ksl | SZH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.450 | |
| 3r43 | ID8 | Aldo-keto reductase family 1 member C3 | / | 0.450 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.450 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.450 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
| 4kzl | 20D | Tankyrase-2 | 2.4.2.30 | 0.450 | |
| 4rv9 | SAH | D-mycarose 3-C-methyltransferase | / | 0.450 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.450 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.450 | |
| 1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 2a4x | BLM | Mitomycin-binding protein | / | 0.449 | |
| 2i9k | SAH | Modification methylase HhaI | 2.1.1.37 | 0.449 | |
| 2j83 | BAT | Ulilysin | 3.4.24 | 0.449 | |
| 2ji6 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.449 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.449 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.449 | |
| 2z7g | EH9 | Adenosine deaminase | 3.5.4.4 | 0.449 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.449 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.449 | |
| 3f6s | FMN | Flavodoxin | / | 0.449 | |
| 3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.449 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.449 | |
| 3ou2 | SAH | SAM-dependent methyltransferase | / | 0.449 | |
| 3thr | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.449 | |
| 3zlm | ANP | Adenosine monophosphate-protein transferase NmFic | 2.7.7.n1 | 0.449 | |
| 4eh8 | IRG | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 4gtp | 7TP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.449 | |
| 4mrx | CZH | Obelin | / | 0.449 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.449 | |
| 1dgg | NDP | Catalase | 1.11.1.6 | 0.448 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.448 | |
| 1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.448 | |
| 1wxj | IPL | Tryptophan synthase alpha chain | / | 0.448 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.448 | |
| 2fhj | H4Z | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.448 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 2z1q | FAD | Acyl-CoA dehydrogenase | / | 0.448 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.448 | |
| 3dlc | SAM | SAM (And some other nucleotide) binding motif:Generic methyltransferase | / | 0.448 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3qpg | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.448 | |
| 3r6p | A8S | Abscisic acid receptor PYL10 | / | 0.448 | |
| 3r7m | SUZ | Aldo-keto reductase family 1 member C3 | / | 0.448 | |
| 3rvi | RVI | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 4jhi | EMU | Nodulin-13 | / | 0.448 | |
| 4qij | 1HA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.448 | |
| 4xo7 | ASD | Aldo-keto reductase family 1 member C2 | / | 0.448 | |
| 1ahg | TYR_PLP | Aspartate aminotransferase | 2.6.1.1 | 0.447 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1eio | GCH | Gastrotropin | / | 0.447 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 1u0w | STL | Chalcone synthase 2 | 2.3.1.74 | 0.447 | |
| 2c92 | TP6 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.447 | |
| 2j5s | KTA | Alr4455 protein | / | 0.447 | |
| 2onz | TMJ | Phenylethanolamine N-methyltransferase | 2.1.1.28 | 0.447 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.447 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 2wky | IBC | Glutamate receptor ionotropic, kainate 1 | / | 0.447 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.447 | |
| 3aba | FLI | Cytochrome P450 | / | 0.447 | |
| 3c49 | KU8 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.447 | |
| 3c72 | CX1 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.447 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.447 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.447 | |
| 3kek | 3EK | Collagenase 3 | 3.4.24 | 0.447 | |
| 3lnb | COA | N-acetyltransferase family protein | / | 0.447 | |
| 3qfr | FMN | NADPH--cytochrome P450 reductase | / | 0.447 | |
| 3qj5 | 022 | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.447 | |
| 5d0r | B1T | Adenylate cyclase type 10 | / | 0.447 | |
| 1eno | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.446 | |
| 1ivr | CBA | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.446 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.446 | |
| 1p33 | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.446 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.446 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.446 | |
| 2bkt | RPF | Renin | 3.4.23.15 | 0.446 | |
| 2cmf | F11 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 2ejz | SAH | Diphthine synthase | / | 0.446 | |
| 2hq9 | FAD | Mll6688 protein | / | 0.446 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.446 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.446 | |
| 2psj | CEI | Renilla-luciferin 2-monooxygenase | 1.13.12.5 | 0.446 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.446 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 2z4z | SC0 | Geranylgeranyl pyrophosphate synthase | / | 0.446 | |
| 3cqe | P91 | Wee1-like protein kinase | 2.7.10.2 | 0.446 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.446 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.446 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.446 | |
| 3m6p | BB2 | Peptide deformylase 1B, chloroplastic/mitochondrial | 3.5.1.88 | 0.446 | |
| 3ndj | JHZ | Methyltransferase | / | 0.446 | |
| 3o0i | P54 | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.446 | |
| 3ug8 | IMN | Aldo-keto reductase family 1 member C3 | / | 0.446 | |
| 4bew | ACP | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.446 | |
| 4hkk | AGI | Tankyrase-2 | 2.4.2.30 | 0.446 | |
| 4i42 | 1HA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.446 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.446 | |
| 4l0t | 1V0 | Tankyrase-2 | 2.4.2.30 | 0.446 | |
| 4li6 | 1XO | Tankyrase-1 | 2.4.2.30 | 0.446 | |
| 4mxe | ACO | N-acetyltransferase ESCO1 | 2.3.1 | 0.446 | |
| 4v0s | 2HN | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.446 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.446 | |
| 4zol | GTP | Tubulin alpha-1B chain | / | 0.446 | |
| 1dli | UDX | UDP-glucose 6-dehydrogenase | / | 0.445 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.445 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1ohj | COP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.445 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.445 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.445 | |
| 2clm | F6F | Tryptophan synthase alpha chain | / | 0.445 | |
| 2nsd | 4PI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 2xf3 | J01 | Uncharacterized protein | / | 0.445 | |
| 2xk4 | OL2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.445 | |
| 2y0j | AXC | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 3d2p | COA | Amino-acid acetyltransferase | / | 0.445 | |
| 3ghw | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.445 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 4bkj | STI | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.445 | |
| 4c49 | HCY | Corticosteroid-binding globulin | / | 0.445 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.445 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.445 | |
| 4few | PP2 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.445 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.445 | |
| 4jv4 | 1OR | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.445 | |
| 4lng | JAN | CaaX farnesyltransferase beta subunit Ram1 | / | 0.445 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.445 | |
| 4pzr | COA | Histone acetyltransferase p300 | / | 0.445 | |
| 4rr7 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.445 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.445 | |
| 1ah3 | TOL | Aldose reductase | 1.1.1.21 | 0.444 | |
| 1frb | ZST | Aldose reductase-related protein 2 | / | 0.444 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.444 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2f2s | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.444 | |
| 2o6h | INI | 6,7-dimethyl-8-ribityllumazine synthase 1 | 2.5.1.78 | 0.444 | |
| 2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 2oaz | I96 | Methionine aminopeptidase 2 | / | 0.444 | |
| 2z2d | HSI | Macrophage metalloelastase | 3.4.24.65 | 0.444 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.444 | |
| 2zcj | SAH | Modification methylase HhaI | 2.1.1.37 | 0.444 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.444 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.444 | |
| 3c36 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.444 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.444 | |
| 3csd | EMO | Putative ketoacyl reductase | 1.3.1 | 0.444 | |
| 3cui | X4S | Exoglucanase/xylanase | 3.2.1.91 | 0.444 | |
| 3ele | PLP | Aminotransferase | / | 0.444 | |
| 3euf | BAU | Uridine phosphorylase 1 | / | 0.444 | |
| 3hxf | BD9 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.444 | |
| 3lm4 | HPX | Catechol 2,3-dioxygenase | / | 0.444 | |
| 3mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.444 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3t0k | DCQ | Sulfide-quinone reductase | / | 0.444 | |
| 3vil | SA0 | Beta-glucosidase | / | 0.444 | |
| 4a6e | ASE | Acetylserotonin O-methyltransferase | 2.1.1.4 | 0.444 | |
| 4j7g | TRH | PCZA361.3 | / | 0.444 | |
| 4j7x | SAS | Sepiapterin reductase | 1.1.1.153 | 0.444 | |
| 4jau | ADP | Sensor histidine kinase | / | 0.444 | |
| 4kc2 | WS2 | Histo-blood group ABO system transferase | / | 0.444 | |
| 4qx5 | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.444 | |
| 10mh | SAH | Modification methylase HhaI | 2.1.1.37 | 0.443 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1e2j | THM | Thymidine kinase | / | 0.443 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1pke | 2FD | Purine nucleoside phosphorylase DeoD-type | / | 0.443 | |
| 1pwu | GM6 | Lethal factor | 3.4.24.83 | 0.443 | |
| 1s1r | NAP | Aldo-keto reductase family 1 member C3 | / | 0.443 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.443 | |
| 1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.443 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.443 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.443 | |
| 2e94 | 364 | Geranylgeranyl pyrophosphate synthase | / | 0.443 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.443 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.443 | |
| 2pa7 | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.443 | |
| 2toh | HBI | Tyrosine 3-monooxygenase | 1.14.16.2 | 0.443 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.443 | |
| 2v95 | HCY | Corticosteroid-binding globulin | / | 0.443 | |
| 2vax | CSC | Acetyl-CoA--deacetylcephalosporin C acetyltransferase | 2.3.1.175 | 0.443 | |
| 2xke | WI2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.443 | |
| 2zyn | BCD | Periplasmic binding protein | / | 0.443 | |
| 3m31 | FAD | Endoplasmic oxidoreductin-1 | 1.8.4 | 0.443 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.443 | |
| 4lcw | 1VY | Major histocompatibility complex class I-related gene protein | / | 0.443 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 4pnr | G18 | Tankyrase-2 | 2.4.2.30 | 0.443 | |
| 4qbj | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.443 | |
| 4rtb | SAM | Putative thiazole biosynthesis protein ThiH | / | 0.443 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.443 | |
| 5c1g | GDU | Histo-blood group ABO system transferase | / | 0.443 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.443 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1osv | CHC | Bile acid receptor | / | 0.442 | |
| 1re0 | AFB | ADP-ribosylation factor 1 | / | 0.442 | |
| 1re0 | AFB | ARF guanine-nucleotide exchange factor 1 | / | 0.442 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.442 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.442 | |
| 1ypj | UIB | Prothrombin | 3.4.21.5 | 0.442 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.442 | |
| 2fl2 | ADP | Kinesin-like protein KIF11 | / | 0.442 | |
| 2oiq | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.442 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
| 2uxi | G50 | HTH-type transcriptional regulator TtgR | / | 0.442 | |
| 2ykv | IK2 | Beta-transaminase | / | 0.442 | |
| 3ba6 | AN2 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.442 | |
| 3bmq | AX5 | Pteridine reductase | / | 0.442 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.442 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3d4b | DZD | NAD-dependent protein deacetylase | / | 0.442 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3e92 | G6A | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.442 | |
| 3hl7 | I46 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3hub | 469 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3iog | SDF | Metallo-beta-lactamase type 2 | / | 0.442 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3neg | PYV | Abscisic acid receptor PYL1 | / | 0.442 | |
| 3pg3 | DG7 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 3tfy | COA | N-alpha-acetyltransferase 50 | 2.3.1 | 0.442 | |
| 3zsg | T75 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.442 | |
| 4cb5 | 93G | Polymerase basic protein 2 | / | 0.442 | |
| 4cf7 | ADP | Adenylate kinase | / | 0.442 | |
| 5dbj | FAD | FADH2-dependent halogenase PltA | / | 0.442 | |
| 1bzf | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1cq8 | PY6 | Aspartate aminotransferase | 2.6.1.1 | 0.441 | |
| 1iep | STI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.441 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.441 | |
| 1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.441 | |
| 1w29 | TS0 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.441 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.441 | |
| 1y5x | E89 | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.441 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.441 | |
| 2ct8 | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.441 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.441 | |
| 2ipj | FFA | Aldo-keto reductase family 1 member C2 | / | 0.441 | |
| 2isc | 223 | Purine nucleoside phosphorylase, putative | / | 0.441 | |
| 2obx | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | 2.5.1.78 | 0.441 | |
| 2v74 | SAH | Histone-arginine methyltransferase CARM1 | / | 0.441 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.441 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 3af4 | GCP | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 3ar5 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.441 | |
| 3fkn | FKN | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.441 | |
| 3len | ZST | Aldose reductase | 1.1.1.21 | 0.441 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.441 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3tqb | FOL | Dihydrofolate reductase | / | 0.441 | |
| 3wi2 | P98 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 4awp | 99A | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 4br0 | AU1 | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.441 | |
| 4eix | NIM | Phospholipase A2 VRV-PL-VIIIa | / | 0.441 | |
| 4iyg | 1HU | Strictosidine synthase | 4.3.3.2 | 0.441 | |
| 4j7u | YTZ | Sepiapterin reductase | 1.1.1.153 | 0.441 | |
| 4jtq | FLP | Aldo-keto reductase family 1 member C2 | / | 0.441 | |
| 4la7 | A1O | Abscisic acid receptor PYL2 | / | 0.441 | |
| 4mm7 | 29J | Na(+):neurotransmitter symporter (Snf family) | / | 0.441 | |
| 7mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.441 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.440 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.440 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.440 | |
| 1k4h | APQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.440 | |
| 1mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.440 | |
| 1p91 | SAM | 23S rRNA (guanine(745)-N(1))-methyltransferase | / | 0.440 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2dv0 | ZST | Aldose reductase | 1.1.1.21 | 0.440 | |
| 2io6 | 330 | Wee1-like protein kinase | 2.7.10.2 | 0.440 | |
| 2o12 | FMN | Chorismate synthase | / | 0.440 | |
| 2pda | TPP | Pyruvate synthase | / | 0.440 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 3dge | ADP | Sensor histidine kinase | / | 0.440 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.440 | |
| 3juq | AKD | Phenazine biosynthesis protein A/B | / | 0.440 | |
| 3o3j | BB4 | Peptide deformylase 1B, chloroplastic/mitochondrial | 3.5.1.88 | 0.440 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.440 | |
| 3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3t88 | S0N | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.440 | |
| 3tfq | 07M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4afe | GGY | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.440 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.440 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.440 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4qtu | SAM | 18S rRNA (guanine(1575)-N(7))-methyltransferase | / | 0.440 | |
| 4tzt | 468 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 5c7h | NDP | Putative oxidoreductase | / | 0.440 | |
| 5dp2 | NAP | CurF | / | 0.440 |