sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.000 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.658 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.539 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.525 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.524 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.524 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.522 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.521 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.520 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.519 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.518 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.517 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.516 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.516 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.516 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.513 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.513 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.512 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.511 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.507 | |
| 2ilv | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.506 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.504 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.504 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.503 | |
| 2cnd | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.503 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.502 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.501 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.501 | |
| 1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.500 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.500 | |
| 3axk | NDP | Ribulose bisphosphate carboxylase large chain | 4.1.1.39 | 0.500 | |
| 3wyc | NAP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.500 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.499 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.499 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.499 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.496 | |
| 3sxj | SAM | Putative methyltransferase | / | 0.496 | |
| 4yj2 | GTP | Tubulin alpha-1B chain | / | 0.496 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.495 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.495 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.495 | |
| 1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.494 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.494 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.494 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.494 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.493 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.493 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.492 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.492 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.492 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.492 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.492 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.491 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.491 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.491 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.491 | |
| 3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.491 | |
| 4fdu | IHS | Putative multiple inositol polyphosphate histidine phosphatase 1 | / | 0.491 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.490 | |
| 1rkw | PNT | HTH-type transcriptional regulator QacR | / | 0.489 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.489 | |
| 2a5h | SAM | L-lysine 2,3-aminomutase | 5.4.3.2 | 0.489 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.489 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.489 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.489 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.488 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.488 | |
| 1szf | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.487 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.487 | |
| 2iib | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.487 | |
| 3a3g | DLZ | Lumazine protein | / | 0.487 | |
| 3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.487 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.486 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.486 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.486 | |
| 2ex1 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.486 | |
| 3toz | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.486 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.485 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.485 | |
| 1umk | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.485 | |
| 4e2d | FMN | Dehydrogenase | / | 0.485 | |
| 4loi | 1YC | Stimulator of interferon genes protein | / | 0.485 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.484 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.484 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.484 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.484 | |
| 4i1c | 1BE | Beta-secretase 1 | 3.4.23.46 | 0.484 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.483 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.483 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.483 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.483 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.483 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.483 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.482 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.482 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.482 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.481 | |
| 2f3f | AXF | Beta-secretase 1 | 3.4.23.46 | 0.481 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.481 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.481 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.481 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.481 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.481 | |
| 1sa5 | BMV | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.480 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.480 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.480 | |
| 4dd8 | BAT | Disintegrin and metalloproteinase domain-containing protein 8 | 3.4.24 | 0.480 | |
| 4zwm | PLP | Ornithine aminotransferase, mitochondrial, putative | / | 0.480 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.480 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.479 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.479 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.479 | |
| 4rvd | SAM | D-mycarose 3-C-methyltransferase | / | 0.479 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.479 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.478 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.478 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.478 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.478 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.478 | |
| 4hyv | PEP | Pyruvate kinase 1 | 2.7.1.40 | 0.478 | |
| 5ao1 | DG3 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.478 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.477 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.477 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.477 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.477 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.477 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.476 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.476 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.476 | |
| 2i3g | NAP | N-acetyl-gamma-glutamyl-phosphate reductase | 1.2.1.38 | 0.476 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.476 | |
| 2vou | FAD | 2,6-dihydroxypyridine 3-monooxygenase | 1.14.13.10 | 0.476 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.476 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.476 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.476 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.476 | |
| 4djh | JDC | Kappa-type opioid receptor | / | 0.476 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.475 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.475 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.475 | |
| 1z44 | FMN | NADPH dehydrogenase | / | 0.475 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.475 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.475 | |
| 3veu | 0GO | Beta-secretase 1 | 3.4.23.46 | 0.475 | |
| 4f5y | C2E | Stimulator of interferon genes protein | / | 0.475 | |
| 4lut | DCS | Alanine racemase | / | 0.475 | |
| 1lrj | UD1 | UDP-glucose 4-epimerase | 5.1.3.2 | 0.474 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.474 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.474 | |
| 2wzw | NDP | Nitroreductase NfnB | / | 0.474 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.474 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.474 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.474 | |
| 4gdc | NDP | UDP-galactopyranose mutase | / | 0.474 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.474 | |
| 1iki | REY | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.473 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.473 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.473 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.473 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.473 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.473 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.472 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.472 | |
| 2cb3 | MLD | Peptidoglycan-recognition protein LE | / | 0.472 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.472 | |
| 2q14 | ADP | Phosphohydrolase | / | 0.472 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.472 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.472 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.472 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.471 | |
| 2a87 | FAD | Thioredoxin reductase | 1.8.1.9 | 0.471 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.471 | |
| 3enk | UPG | UDP-glucose 4-epimerase | / | 0.471 | |
| 3jyq | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.471 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.471 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.471 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.471 | |
| 4yp6 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.471 | |
| 5kwv | ANP | Pantothenate synthetase | / | 0.471 | |
| 5d5b | CAU | Beta-2 adrenergic receptor | / | 0.471 | |
| 5d6l | CAU | Beta-2 adrenergic receptor | / | 0.471 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.470 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.470 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.470 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.470 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.470 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.470 | |
| 4i9n | 1E5 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.470 | |
| 5ftf | ADP | TPR domain protein | / | 0.470 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.469 | |
| 3o0o | 5AD | Vitamin B12-dependent ribonucleotide reductase | / | 0.469 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.469 | |
| 3qfb | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.469 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.469 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.469 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.468 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.468 | |
| 2daa | DCS | D-alanine aminotransferase | 2.6.1.21 | 0.468 | |
| 3kxw | 1ZZ | Saframycin Mx1 synthetase B | / | 0.468 | |
| 4jic | FMN | GTN Reductase | / | 0.468 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.468 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.468 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.468 | |
| 5eio | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.468 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.467 | |
| 1daa | PLP | D-alanine aminotransferase | 2.6.1.21 | 0.467 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.467 | |
| 2gz7 | D3F | Orf1a polyprotein | / | 0.467 | |
| 3ut5 | LOC | Tubulin beta chain | / | 0.467 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.467 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.466 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.466 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.466 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.466 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.466 | |
| 3l5l | FMN | Xenobiotic reductase | / | 0.466 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.466 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.466 | |
| 3wqu | ATP | Cell division protein FtsA | / | 0.466 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.466 | |
| 4ddy | DN6 | Beta-lactamase | / | 0.466 | |
| 4j1k | 1HG | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
| 5d5a | CAU | Beta-2 adrenergic receptor | / | 0.466 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.465 | |
| 1kbi | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.465 | |
| 1q6t | 600 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.465 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.465 | |
| 2anb | 5GP | Guanylate kinase | 2.7.4.8 | 0.465 | |
| 3dm5 | GDP | Signal recognition particle 54 kDa protein | / | 0.465 | |
| 3hlw | CE3 | Beta-lactamase | / | 0.465 | |
| 3n19 | FNR | Xenobiotic reductase | / | 0.465 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.465 | |
| 4lxk | 1YT | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 4tmb | FMN | Old yellow enzyme | / | 0.465 | |
| 4xrb | NDP | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.465 | |
| 5cho | FAD | Flavin reductase | / | 0.465 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.464 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.464 | |
| 1ld8 | U49 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.464 | |
| 1mbb | EEB | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.464 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.464 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.464 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 2xy3 | DUP | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.464 | |
| 3kpb | SAM | Uncharacterized protein MJ0100 | / | 0.464 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.464 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.464 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.464 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.464 | |
| 3vsx | R32 | Renin | 3.4.23.15 | 0.464 | |
| 4brg | GNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.464 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.464 | |
| 4j4n | D44 | Peptidylprolyl isomerase | / | 0.464 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.463 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.463 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.463 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.463 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.463 | |
| 3int | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.463 | |
| 3p0j | TYE | Putative tyrosyl-tRNA synthetase | / | 0.463 | |
| 3p80 | P80 | Pentaerythritol tetranitrate reductase | / | 0.463 | |
| 4c13 | UML | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase | / | 0.463 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.463 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.463 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.463 | |
| 1d0l | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.462 | |
| 1hzz | NAP | NAD(P) transhydrogenase subunit beta | 1.6.1.2 | 0.462 | |
| 1jue | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.462 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.462 | |
| 1ra3 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.462 | |
| 2g20 | L1A | Renin | 3.4.23.15 | 0.462 | |
| 2wwj | Y28 | Lysine-specific demethylase 4A | / | 0.462 | |
| 2ylr | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.462 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.462 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.462 | |
| 3o7b | SAH | Ribosomal RNA small subunit methyltransferase Nep1 | / | 0.462 | |
| 3ty3 | GGG | Homoisocitrate dehydrogenase | 1.1.1.87 | 0.462 | |
| 4c49 | HCY | Corticosteroid-binding globulin | / | 0.462 | |
| 4f9g | C2E | Stimulator of interferon genes protein | / | 0.462 | |
| 4k9h | 1QU | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.461 | |
| 1jzq | ILA | Isoleucine--tRNA ligase | 6.1.1.5 | 0.461 | |
| 1n7h | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.461 | |
| 2ewv | ADP | Twitching motility protein PilT | / | 0.461 | |
| 2ii6 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.461 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.461 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 2yd0 | BES | Endoplasmic reticulum aminopeptidase 1 | 3.4.11 | 0.461 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.461 | |
| 3hl4 | CDC | Choline-phosphate cytidylyltransferase A | / | 0.461 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.461 | |
| 3kkz | SAM | Uncharacterized protein | / | 0.461 | |
| 3u9e | COA | Lmo1369 protein | / | 0.461 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 4pgh | SAM | Caffeic acid O-methyltransferase | / | 0.461 | |
| 5c41 | ACP | Ribokinase | / | 0.461 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.460 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.460 | |
| 1vhz | APR | ADP compounds hydrolase NudE | 3.6.1 | 0.460 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.460 | |
| 2dvo | ITT | dITP/XTP pyrophosphatase | 3.6.1.19 | 0.460 | |
| 2gtb | AZP | Orf1ab polyprotein | / | 0.460 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.460 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.460 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.460 | |
| 3ag6 | PAJ | Pantothenate synthetase | / | 0.460 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.460 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.460 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 3nut | SAH | Precorrin-3 methylase | / | 0.460 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.460 | |
| 3wag | TYD | Glycosyltransferase | / | 0.460 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.460 | |
| 4ef4 | C2E | Stimulator of interferon genes protein | / | 0.460 | |
| 4ewo | 996 | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 4ikz | AFS | Di-tripeptide ABC transporter (Permease) | / | 0.460 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.460 | |
| 5czy | SAM | Eukaryotic huntingtin interacting protein B | / | 0.460 | |
| 5itz | LOC | Tubulin beta-2B chain | / | 0.460 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.459 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.459 | |
| 1hzj | UD1 | UDP-glucose 4-epimerase | / | 0.459 | |
| 1ja0 | NAP | NADPH--cytochrome P450 reductase | / | 0.459 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.459 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.459 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.459 | |
| 2hpv | FMN | FMN-dependent NADH-azoreductase | 1.7 | 0.459 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.459 | |
| 3k5f | AYH | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.459 | |
| 3mo0 | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.459 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.459 | |
| 3t0i | SAH | Putative methyltransferase | / | 0.459 | |
| 4b00 | I6X | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 4b65 | FAD | L-ornithine N(5)-monooxygenase | / | 0.459 | |
| 4bqz | GNP | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.459 | |
| 4exg | 916 | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 4fuj | 1U9 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.459 | |
| 4nv1 | TYD | Formyl transferase | / | 0.459 | |
| 1c9k | 5GP | Bifunctional adenosylcobalamin biosynthesis protein CobU | / | 0.458 | |
| 1eyy | NAP | NADP-dependent fatty aldehyde dehydrogenase | 1.2.1.4 | 0.458 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.458 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.458 | |
| 1uxy | EPU | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.458 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.458 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.458 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.458 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.458 | |
| 2wez | ZYE | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.458 | |
| 3ad9 | FAD | Subunit beta of sarcosine oxidase | / | 0.458 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.458 | |
| 4a0r | DTB | Bifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial | 6.3.3.3 | 0.458 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.458 | |
| 4bk2 | FAD | Probable salicylate monooxygenase | / | 0.458 | |
| 4iv6 | FDA | Isovaleryl-CoA dehydrogenase | / | 0.458 | |
| 4j0t | 6T9 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.458 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.457 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.457 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.457 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 3b4p | 3B4 | Phenazine biosynthesis protein A/B | / | 0.457 | |
| 3bbr | BHY | Glutamate receptor 2 | / | 0.457 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 3kru | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.457 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.457 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.457 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.457 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.457 | |
| 4z26 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.457 | |
| 1d0m | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.456 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.456 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.456 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.456 | |
| 1v0j | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.456 | |
| 1xdp | ATP | Polyphosphate kinase | / | 0.456 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.456 | |
| 2po3 | T4K | 4-dehydrase | / | 0.456 | |
| 2r2l | PB9 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.456 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.456 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.456 | |
| 3ksq | Z96 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.456 | |
| 3nxq | RX4 | Angiotensin-converting enzyme | 3.2.1 | 0.456 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.456 | |
| 4b0q | GMF | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 4bf9 | FMN | tRNA-dihydrouridine(16) synthase | / | 0.456 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.456 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.456 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.456 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.455 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.455 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.455 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.455 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 2vij | C44 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.455 | |
| 2z3l | PHE_ARG_TYR_LEU_GLY | Leucyl/phenylalanyl-tRNA--protein transferase | 2.3.2.6 | 0.455 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.455 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.455 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.455 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.455 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.455 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.455 | |
| 4m5p | FMN | NADPH dehydrogenase | / | 0.455 | |
| 4rvf | TYD | D-mycarose 3-C-methyltransferase | / | 0.455 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.455 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1e1k | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.454 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.454 | |
| 1r6t | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.454 | |
| 1rz0 | FAD | Phenol 2-hydroxylase component B | / | 0.454 | |
| 1ty9 | FMN | Phenazine biosynthesis protein PhzG | 1.4 | 0.454 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.454 | |
| 2ejz | SAH | Diphthine synthase | / | 0.454 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.454 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.454 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.454 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.454 | |
| 3d3x | ARG_ILE_MET_GLU_NH2 | Type E botulinum toxin | / | 0.454 | |
| 3ivx | FG6 | Pantothenate synthetase | 6.3.2.1 | 0.454 | |
| 3q8u | ADP | Nucleoside diphosphate kinase | / | 0.454 | |
| 3v2u | ATP | Protein GAL3 | / | 0.454 | |
| 3vg1 | 0GT | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4blr | UTP | NTPase P4 | / | 0.454 | |
| 4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.454 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 4dri | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.454 | |
| 4dri | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.454 | |
| 4fkz | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.454 | |
| 4gtp | 7TP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.454 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.454 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.454 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.454 | |
| 4x7w | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.454 | |
| 1a5b | IGP | Tryptophan synthase alpha chain | / | 0.453 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.453 | |
| 1h6c | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.453 | |
| 1ja1 | FMN | NADPH--cytochrome P450 reductase | / | 0.453 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.453 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.453 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.453 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.453 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.453 | |
| 2gs9 | SAH | Uncharacterized protein | / | 0.453 | |
| 2jl1 | NAP | Triphenylmethane reductase | / | 0.453 | |
| 2qc8 | ADP | Glutamine synthetase | 6.3.1.2 | 0.453 | |
| 2wf4 | ZY4 | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 0.453 | |
| 3dzi | RGT | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.453 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.453 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.453 | |
| 3tdj | 3TJ | Glutamate receptor 2 | / | 0.453 | |
| 4bxk | 1IU | Angiotensin-converting enzyme | 3.2.1 | 0.453 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.453 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.453 | |
| 4i10 | 1BS | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.453 | |
| 4rnv | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.453 | |
| 4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.453 | |
| 5ah5 | LSS | Leucine--tRNA ligase | / | 0.453 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.452 | |
| 1i5c | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.452 | |
| 1obb | NAD | Alpha-glucosidase | 3.2.1.20 | 0.452 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.452 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.452 | |
| 2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.452 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.452 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.452 | |
| 2qs4 | LY5 | Glutamate receptor ionotropic, kainate 1 | / | 0.452 | |
| 2r8o | T5X | Transketolase 1 | / | 0.452 | |
| 2vkm | BSD | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.452 | |
| 3lzw | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.452 | |
| 3ojw | FMN | NADPH--cytochrome P450 reductase | / | 0.452 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3wid | NAP | Glucose 1-dehydrogenase | / | 0.452 | |
| 4b1c | 1B1 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4e2b | FMN | Dehydrogenase | / | 0.452 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.452 | |
| 4gd4 | 0WS | Lysine-specific demethylase 4A | 1.14.11 | 0.452 | |
| 4jay | NAP | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.452 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.452 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.451 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.451 | |
| 1fcb | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.451 | |
| 1gpu | THD | Transketolase 1 | 2.2.1.1 | 0.451 | |
| 1kvu | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.451 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.451 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 1typ | FAD | Trypanothione reductase | 1.8.1.12 | 0.451 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.451 | |
| 1yqs | BSA | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.451 | |
| 1zrq | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.451 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.451 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.451 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.451 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 2ohv | NHL | Glutamate racemase | / | 0.451 | |
| 2wvl | GDD | Mannosyl-3-phosphogylcerate synthase | / | 0.451 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.451 | |
| 3ckq | UPG | Glucosyl-3-phosphoglycerate synthase | 2.4.1.266 | 0.451 | |
| 3i25 | MV7 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 3ixk | 929 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 3pmy | 41L | Endothiapepsin | 3.4.23.22 | 0.451 | |
| 3pw8 | ACO | 1,2-phenylacetyl-CoA epoxidase, subunit A | 1.14.13.149 | 0.451 | |
| 3px3 | T3Q | dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase | 2.1.1.235 | 0.451 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.451 | |
| 3skg | PB8 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.451 | |
| 4b05 | 32D | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.451 | |
| 4gav | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.451 | |
| 4lol | 1YE | Stimulator of interferon genes protein | / | 0.451 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.451 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.450 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.450 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1n4q | LYS_CYS_VAL_ILE_LEU | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.450 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.450 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.450 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.450 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.450 | |
| 3e32 | ED2 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.450 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.450 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.450 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.450 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.450 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3tjl | FMN | NADPH dehydrogenase | / | 0.450 | |
| 3w1q | YRO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.450 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 4e2x | TYD | Methyltransferase | / | 0.450 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.450 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.450 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.450 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.449 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1owe | 675 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.449 | |
| 1ra3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.449 | |
| 2hu2 | NAD | C-terminal binding protein 1 | / | 0.449 | |
| 2q3r | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.449 | |
| 2r8p | T6F | Transketolase 1 | / | 0.449 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.449 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.449 | |
| 3i12 | ADP | D-alanine--D-alanine ligase A | 6.3.2.4 | 0.449 | |
| 3l9h | EMQ | Kinesin-like protein KIF11 | / | 0.449 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.449 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.449 | |
| 4de1 | 0J6 | Beta-lactamase | / | 0.449 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.449 | |
| 4hmw | FMN | Pyridoxamine 5'-phosphate oxidase | / | 0.449 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.449 | |
| 4rnw | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.449 | |
| 4xbj | IN5 | Alanine racemase, biosynthetic | / | 0.449 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1cne | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.448 | |
| 1dj2 | GDP | Adenylosuccinate synthetase, chloroplastic | / | 0.448 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.448 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.448 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.448 | |
| 1i6k | TYM | Tryptophan--tRNA ligase | 6.1.1.2 | 0.448 | |
| 1n77 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.448 | |
| 1v5y | 4HC | Major NAD(P)H-flavin oxidoreductase | 1.6.99 | 0.448 | |
| 1z48 | FMN | NADPH dehydrogenase | / | 0.448 | |
| 2f3e | AXQ | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 2ha8 | SAH | Probable methyltransferase TARBP1 | / | 0.448 | |
| 2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.448 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2wzw | FMN | Nitroreductase NfnB | / | 0.448 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.448 | |
| 3cb2 | GDP | Tubulin gamma-1 chain | / | 0.448 | |
| 3dm6 | 757 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.448 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.448 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.448 | |
| 3m4p | 4AD | Asparaginyl-tRNA synthetase, putative | / | 0.448 | |
| 3nd6 | ATP | Phosphopantetheine adenylyltransferase | / | 0.448 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.448 | |
| 3t4n | ADP | 5'-AMP-activated protein kinase subunit gamma | / | 0.448 | |
| 3uku | C69 | Actin-related protein 3 | / | 0.448 | |
| 3vaq | ADN | Putative adenosine kinase | / | 0.448 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.448 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.448 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4qly | FMN | Enone reductase CLA-ER | / | 0.448 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.447 | |
| 1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1fxu | GU7 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.447 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.447 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1l7x | 700 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.447 | |
| 1ld7 | U66 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.447 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.447 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.447 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.447 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.447 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.447 | |
| 2fdp | FRP | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 2gna | GDU | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.447 | |
| 2gou | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.447 | |
| 2irz | I02 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.447 | |
| 3fsj | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.447 | |
| 3gvi | ADP | Malate dehydrogenase | / | 0.447 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.447 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.447 | |
| 3mtw | M3R | Xaa-Pro dipeptidase, putative | / | 0.447 | |
| 3opx | U5P | Suppressor of disruption of TFIIS | / | 0.447 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.447 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 4e2y | JHZ | Methyltransferase | / | 0.447 | |
| 4fse | 0VA | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.447 | |
| 4k8s | 1QT | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.447 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.447 | |
| 4wzh | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.447 | |
| 5a01 | 12V | O-glycosyltransferase | / | 0.447 | |
| 5dw5 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.447 | |
| 1c6y | MK1 | Protease | / | 0.446 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.446 | |
| 1n2h | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.446 | |
| 1ra8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.446 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.446 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.446 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.446 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 2ge3 | ACO | Probable acetyltransferase | / | 0.446 | |
| 2vj6 | VG5 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3b9x | NOS | Pyrimidine-specific ribonucleoside hydrolase RihB | 3.2.2.8 | 0.446 | |
| 3c8a | ARG_ARG_GLY_LEU_NH2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.446 | |
| 3cow | 52H | Pantothenate synthetase | 6.3.2.1 | 0.446 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.446 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.446 | |
| 3n14 | FMN | Xenobiotic reductase | / | 0.446 | |
| 3ukf | GDU | UDP-galactopyranose mutase | / | 0.446 | |
| 3vjk | M51 | Dipeptidyl peptidase 4 | / | 0.446 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.446 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.446 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.446 | |
| 4ccq | FAD | Thioredoxin reductase | / | 0.446 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.446 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.446 | |
| 4eud | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.446 | |
| 4iaw | LIZ | Neutrophil gelatinase-associated lipocalin | / | 0.446 | |
| 4j75 | TYM | Tryptophan--tRNA ligase | / | 0.446 | |
| 4kuh | CAA | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.446 | |
| 4l7j | 1W2 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4qxp | 1YE | Stimulator of interferon genes protein | / | 0.446 | |
| 4qxq | 1YE | Stimulator of interferon genes protein | / | 0.446 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.446 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.446 | |
| 1bwk | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.445 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.445 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.445 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.445 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.445 | |
| 1mmk | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.445 | |
| 1rct | NOS | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.445 | |
| 2djx | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.445 | |
| 2fre | FMN | NAD(P)H-flavin oxidoreductase | / | 0.445 | |
| 2rgj | FAD | Flavin-containing monooxygenase | / | 0.445 | |
| 3coy | 53H | Pantothenate synthetase | 6.3.2.1 | 0.445 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.445 | |
| 3r96 | ACO | MccE protein | / | 0.445 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.445 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.445 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.445 | |
| 4usr | FAD | Monooxygenase | / | 0.445 | |
| 4wpu | GDP | Phosphoenolpyruvate carboxykinase [GTP] | / | 0.445 | |
| 4xr9 | NAD | CalS8 | / | 0.445 | |
| 3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.445 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.444 | |
| 1f8g | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.444 | |
| 1h61 | PDN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 1hon | GNH | Adenylosuccinate synthetase | / | 0.444 | |
| 1knp | FAD | L-aspartate oxidase | 1.4.3.16 | 0.444 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 1nfy | RTR | Coagulation factor X | 3.4.21.6 | 0.444 | |
| 1nly | AGS | Cag alpha | / | 0.444 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.444 | |
| 2d3a | ADP | Glutamine synthetase root isozyme 3 | 6.3.1.2 | 0.444 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.444 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.444 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.444 | |
| 2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2viy | VG3 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2xyt | TC9 | Soluble acetylcholine receptor | / | 0.444 | |
| 2yqs | UD1 | UDP-N-acetylglucosamine pyrophosphorylase | 2.7.7.23 | 0.444 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.444 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3djg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.444 | |
| 3dv3 | MEK | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.444 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.444 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.444 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.444 | |
| 3ukl | FAD | UDP-galactopyranose mutase | / | 0.444 | |
| 3w23 | 3RO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.444 | |
| 3zcs | CAW | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.444 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4ke0 | 1R8 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4rel | KMP | Glycosyltransferase | / | 0.444 | |
| 4yer | ADP | Antibiotic ABC transporter, ATP-binding protein, putative | / | 0.444 | |
| 5aga | ANP | DNA polymerase theta | / | 0.444 | |
| 1a59 | COA | 2-methylcitrate synthase | / | 0.443 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.443 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 1jdt | MTA | Purine nucleoside phosphorylase | / | 0.443 | |
| 1lc3 | NAD | Biliverdin reductase A | 1.3.1.24 | 0.443 | |
| 1v45 | 3DG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 2b4r | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.443 | |
| 2bf4 | FAD | NADPH--cytochrome P450 reductase | / | 0.443 | |
| 2e1z | B4P | Propionate kinase | / | 0.443 | |
| 2q9c | GNP | Signal recognition particle receptor FtsY | / | 0.443 | |
| 2v2z | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.443 | |
| 2vf3 | GVS | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.443 | |
| 2viz | VG4 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 2xnv | VU3 | Soluble acetylcholine receptor | / | 0.443 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.443 | |
| 2z3n | PHE_ARG_TYR_LEU_GLY | Leucyl/phenylalanyl-tRNA--protein transferase | 2.3.2.6 | 0.443 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.443 | |
| 3c7d | NAD | Octopine dehydrogenase | / | 0.443 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.443 | |
| 3dsz | LIZ | Neutrophil gelatinase-associated lipocalin | / | 0.443 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.443 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.443 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.443 | |
| 3jv7 | NAD | Secondary alcohol dehydrogenase | / | 0.443 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 3pft | FMN | Flavin reductase | / | 0.443 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.443 | |
| 3s87 | ADP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.443 | |
| 3vjl | W94 | Dipeptidyl peptidase 4 | / | 0.443 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.443 | |
| 3wsw | NAD | L-lactate dehydrogenase | / | 0.443 | |
| 3wwm | ADP | [LysW]-aminoadipate kinase | / | 0.443 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.443 | |
| 4g2r | H1L | Probable propionyl-CoA carboxylase beta chain 6 | 6.4.1.3 | 0.443 | |
| 4gsu | DWZ | L,D-transpeptidase 2 | 2.3.2 | 0.443 | |
| 4i13 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.443 | |
| 4u3j | GTP | Tubulin beta chain | / | 0.443 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.443 | |
| 4z0p | NDP | NAD-dependent dehydrogenase | / | 0.443 | |
| 5cku | FAD | L-ornithine N(5)-monooxygenase | / | 0.443 | |
| 5fwn | NAP | Putative dehydrogenase | / | 0.443 | |
| 1esv | LAR | Actin, alpha skeletal muscle | / | 0.442 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 1kbj | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.442 | |
| 1l5s | 700 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.442 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.442 | |
| 1s63 | 778 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.442 | |
| 1wbt | WBT | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.442 | |
| 2fs4 | PZ1 | Renin | 3.4.23.15 | 0.442 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.442 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 2pb2 | PLP | Acetylornithine/succinyldiaminopimelate aminotransferase | 2.6.1.11 | 0.442 | |
| 2q96 | A18 | Methionine aminopeptidase | / | 0.442 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.442 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.442 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.442 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.442 | |
| 3muo | ZPR | Prolyl endopeptidase | / | 0.442 | |
| 3ppr | 4CS | Glycine betaine/carnitine/choline-binding protein OpuCC | / | 0.442 | |
| 3ua8 | 08W | Glutamate receptor 2 | / | 0.442 | |
| 3vf3 | 0GS | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.442 | |
| 4bzb | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.442 | |
| 4d0l | 093 | Phosphatidylinositol 4-kinase beta | 2.7.1.67 | 0.442 | |
| 4de0 | 0JB | Beta-lactamase | / | 0.442 | |
| 4gid | 0GH | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4nes | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.442 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.442 | |
| 4qfy | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.442 | |
| 4rv9 | SAH | D-mycarose 3-C-methyltransferase | / | 0.442 | |
| 5a9s | NAP | Putative dehydrogenase | / | 0.442 | |
| 1a9c | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.441 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.441 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 1il0 | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.441 | |
| 1nj6 | A5A | Proline--tRNA ligase | / | 0.441 | |
| 1od1 | 0QS | Endothiapepsin | 3.4.23.22 | 0.441 | |
| 1ppj | ANY | Cytochrome b | / | 0.441 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.441 | |
| 1sa4 | JAN | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.441 | |
| 1snf | UMP | Deoxyuridine 5'-triphosphate nucleotidohydrolase | 3.6.1.23 | 0.441 | |
| 1vf3 | GDN | Glutathione S-transferase 3 | 2.5.1.18 | 0.441 | |
| 2a7r | 5GP | GMP reductase 2 | / | 0.441 | |
| 2b8v | 3BN | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.441 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.441 | |
| 2gqg | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.441 | |
| 2j07 | HDF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.441 | |
| 2wf1 | ZY1 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2wp9 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.441 | |
| 2wp9 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.441 | |
| 2yj4 | ATP | Copper-transporting ATPase | / | 0.441 | |
| 2zbw | FAD | Ferredoxin--NADP reductase | / | 0.441 | |
| 2zff | 53U | Prothrombin | 3.4.21.5 | 0.441 | |
| 3af3 | GCP | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.441 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
| 3ioe | A7D | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
| 3ivg | FG5 | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
| 3mdd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.441 | |
| 3oix | FMN | Dihydroorotate dehydrogenase | / | 0.441 | |
| 3r2f | PB0 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3tnl | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.441 | |
| 3wv7 | ADP | Hmd co-occurring protein HcgE | / | 0.441 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.441 | |
| 4yaw | 2AM | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 1b8u | NAD | Malate dehydrogenase | / | 0.440 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.440 | |
| 1kw0 | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.440 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.440 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.440 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.440 | |
| 1ywg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.440 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.440 | |
| 2ck3 | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.440 | |
| 2ck3 | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.440 | |
| 2fon | FAD | Acyl-coenzyme A oxidase | / | 0.440 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.440 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.440 | |
| 2gh5 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.440 | |
| 2iea | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.440 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.440 | |
| 2zdv | 37U | Prothrombin | 3.4.21.5 | 0.440 | |
| 3giy | FMN | (S)-mandelate dehydrogenase | 1.1.99.31 | 0.440 | |
| 3iqg | ASN_TRP_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.440 | |
| 3mx5 | UTP | Nucleoprotein | / | 0.440 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.440 | |
| 4b1e | 6T6 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4brd | ANP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.440 | |
| 4de2 | DN3 | Beta-lactamase | / | 0.440 | |
| 4dro | 0MD | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.440 | |
| 4fpy | 0V8 | Sialidase B | 3.2.1.18 | 0.440 | |
| 4fsl | 0VB | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4hmx | FMN | Pyridoxamine 5'-phosphate oxidase | / | 0.440 | |
| 4j7h | TRH | PCZA361.3 | / | 0.440 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.440 | |
| 4lrz | ADP | PEP-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL | 2.7 | 0.440 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.440 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.440 | |
| 4zea | IMI | Endothiapepsin | 3.4.23.22 | 0.440 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 8dfr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 |