sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4yp6 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4yp6 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 1.000 | |
| 1m8k | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.560 | |
| 5kwv | ANP | Pantothenate synthetase | / | 0.543 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.538 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.516 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.516 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.514 | |
| 3isj | A8D | Pantothenate synthetase | 6.3.2.1 | 0.514 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.512 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.511 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.510 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.510 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.508 | |
| 4jic | FMN | GTN Reductase | / | 0.508 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.505 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.503 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.503 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.501 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.500 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.498 | |
| 3fhy | ATP | Pyridoxal kinase | 2.7.1.35 | 0.498 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.497 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.496 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.495 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.495 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.494 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.494 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.493 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.493 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.493 | |
| 1cjv | FOK | Adenylate cyclase type 2 | / | 0.492 | |
| 1cjv | FOK | Adenylate cyclase type 5 | / | 0.492 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.492 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.492 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.492 | |
| 1jed | ADP | Sulfate adenylyltransferase | / | 0.491 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.491 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.491 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.491 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.491 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.490 | |
| 1i5c | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.490 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.490 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.490 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.489 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.489 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.489 | |
| 1a5b | IGP | Tryptophan synthase alpha chain | / | 0.487 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.487 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.487 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.487 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.487 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.487 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.486 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.486 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.485 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.485 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.485 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.485 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.484 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.484 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.484 | |
| 3u9e | COA | Lmo1369 protein | / | 0.484 | |
| 5cfp | C2E | Stimulator of interferon genes protein | / | 0.484 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.483 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.483 | |
| 2pak | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.483 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.483 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.482 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.482 | |
| 4ge9 | 0L0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.482 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.481 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.481 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.481 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.481 | |
| 3v2u | ATP | Protein GAL3 | / | 0.481 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.481 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.480 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.480 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.480 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.480 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.480 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.480 | |
| 4ca6 | 3EF | Angiotensin-converting enzyme | 3.2.1 | 0.480 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.480 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.480 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.480 | |
| 1ja1 | FMN | NADPH--cytochrome P450 reductase | / | 0.479 | |
| 1wxj | IPL | Tryptophan synthase alpha chain | / | 0.479 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.479 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.479 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.479 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.479 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.479 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.478 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.478 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.478 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.478 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.478 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.478 | |
| 4j4n | D44 | Peptidylprolyl isomerase | / | 0.478 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.477 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.477 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.477 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.477 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.477 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.477 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.476 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.476 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.476 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.476 | |
| 3coy | 53H | Pantothenate synthetase | 6.3.2.1 | 0.476 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.476 | |
| 3g5m | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.476 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.476 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.476 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.476 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.476 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.476 | |
| 4qnw | FMN | Chanoclavine-I aldehyde reductase easA | / | 0.476 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.475 | |
| 3h1v | TK1 | Glucokinase | 2.7.1.2 | 0.475 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.475 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.474 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.474 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.474 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.474 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.474 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.474 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.474 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.473 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.473 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.473 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 2d3a | ADP | Glutamine synthetase root isozyme 3 | 6.3.1.2 | 0.473 | |
| 3rvh | HQ2 | Lysine-specific demethylase 4A | 1.14.11 | 0.473 | |
| 4loi | 1YC | Stimulator of interferon genes protein | / | 0.473 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.472 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.472 | |
| 2ii6 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.472 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.472 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.472 | |
| 4lut | DCS | Alanine racemase | / | 0.472 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.471 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.471 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.471 | |
| 1jzq | ILA | Isoleucine--tRNA ligase | 6.1.1.5 | 0.471 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.471 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.471 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.471 | |
| 2yd0 | BES | Endoplasmic reticulum aminopeptidase 1 | 3.4.11 | 0.471 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.471 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.471 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.471 | |
| 3rba | COD | Phosphopantetheine adenylyltransferase | / | 0.471 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.471 | |
| 5ah5 | LSS | Leucine--tRNA ligase | / | 0.471 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.471 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.471 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.470 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.470 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.470 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.470 | |
| 2gz7 | D3F | Orf1a polyprotein | / | 0.470 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.470 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.470 | |
| 3e8x | NAP | BH1520 protein | / | 0.470 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.470 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.470 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.470 | |
| 3qfr | FMN | NADPH--cytochrome P450 reductase | / | 0.470 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.470 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.470 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.470 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.469 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.469 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.469 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.469 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.469 | |
| 3h86 | AP5 | Adenylate kinase | / | 0.469 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.469 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.469 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.469 | |
| 1amo | FMN | NADPH--cytochrome P450 reductase | / | 0.468 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.468 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.468 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.468 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.468 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.468 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.468 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.468 | |
| 4gyy | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.468 | |
| 4yj2 | GTP | Tubulin alpha-1B chain | / | 0.468 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.468 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.468 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.467 | |
| 2gtb | AZP | Orf1ab polyprotein | / | 0.467 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.467 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.467 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.467 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.467 | |
| 1eio | GCH | Gastrotropin | / | 0.466 | |
| 1u0h | FOK | Adenylate cyclase type 2 | / | 0.466 | |
| 1u0h | FOK | Adenylate cyclase type 5 | / | 0.466 | |
| 1uxy | EPU | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.466 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.466 | |
| 2xq0 | BES | Leukotriene A-4 hydrolase homolog | 3.3.2.6 | 0.466 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.466 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.466 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.466 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.466 | |
| 5eio | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.466 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.465 | |
| 1nuq | NXX | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.465 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.465 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.465 | |
| 2h8x | FMN | XenA | / | 0.465 | |
| 3c15 | FOK | Adenylate cyclase type 2 | / | 0.465 | |
| 3c15 | FOK | Adenylate cyclase type 5 | / | 0.465 | |
| 3ojw | FMN | NADPH--cytochrome P450 reductase | / | 0.465 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.465 | |
| 5cho | FAD | Flavin reductase | / | 0.465 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.464 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.464 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.464 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.464 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.464 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.464 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.464 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.464 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.464 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.464 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.464 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.464 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.464 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.464 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.463 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.463 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 2iib | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.463 | |
| 2j09 | FMN | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.463 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.463 | |
| 3dv3 | MEK | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.463 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.463 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.463 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.463 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.463 | |
| 5ftf | ADP | TPR domain protein | / | 0.463 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.462 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 2an9 | GDP | Guanylate kinase | 2.7.4.8 | 0.462 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.462 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.462 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.462 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.462 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.462 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.462 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.462 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.462 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.462 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.462 | |
| 3kmx | G00 | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.462 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.462 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.461 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.461 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.461 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.461 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.461 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.461 | |
| 2dvo | ITT | dITP/XTP pyrophosphatase | 3.6.1.19 | 0.461 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.461 | |
| 2i7n | ACO | Pantothenate kinase 1 | 2.7.1.33 | 0.461 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.461 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.461 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.461 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.461 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.461 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 4g48 | PZB | Mycocyclosin synthase | 1.14.21.9 | 0.461 | |
| 4iq7 | 1G9 | Mycocyclosin synthase | 1.14.21.9 | 0.461 | |
| 5doz | NDP | JamJ | / | 0.461 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.460 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.460 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.460 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.460 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.460 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 3axk | NDP | Ribulose bisphosphate carboxylase large chain | 4.1.1.39 | 0.460 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.460 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 4h49 | L29 | Macrophage metalloelastase | 3.4.24.65 | 0.460 | |
| 4x7w | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.460 | |
| 4zwm | PLP | Ornithine aminotransferase, mitochondrial, putative | / | 0.460 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.459 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.459 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.459 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.459 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.459 | |
| 2hm1 | LIQ | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 2pck | SAH | Diphthine synthase | / | 0.459 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.459 | |
| 2wwj | Y28 | Lysine-specific demethylase 4A | / | 0.459 | |
| 3eku | CY9 | Actin-5C | / | 0.459 | |
| 3jzd | NAD | Maleylacetate reductase | / | 0.459 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 3l5l | FMN | Xenobiotic reductase | / | 0.459 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.459 | |
| 4id9 | NAD | Putative UDP-glucose 4-epimerase | / | 0.459 | |
| 1l7x | 700 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.458 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.458 | |
| 2bf4 | FMN | NADPH--cytochrome P450 reductase | / | 0.458 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.458 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.458 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.458 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.458 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.458 | |
| 4fse | 0VA | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 4hmv | WUB | Phenazine biosynthesis protein PhzG | 1.4 | 0.458 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.458 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.457 | |
| 1oxo | IK2 | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.457 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.457 | |
| 2g2z | COZ | Malonyl CoA-acyl carrier protein transacylase | 2.3.1.39 | 0.457 | |
| 2gmj | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.457 | |
| 2gou | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.457 | |
| 2ome | NAD | C-terminal-binding protein 2 | / | 0.457 | |
| 2xyt | TC9 | Soluble acetylcholine receptor | / | 0.457 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.457 | |
| 3ieu | GDP | GTPase Era | / | 0.457 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.457 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.457 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.457 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.457 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.457 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.457 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.457 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.457 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.457 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 2ex1 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.456 | |
| 2j07 | HDF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.456 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.456 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.456 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.456 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.456 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.456 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.456 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.456 | |
| 3kkz | SAM | Uncharacterized protein | / | 0.456 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.456 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.456 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.455 | |
| 1w76 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.455 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.455 | |
| 2eix | FAD | NADH-cytochrome b5 reductase | / | 0.455 | |
| 2o7o | DXT | Tetracycline repressor protein class D | / | 0.455 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 2p9d | SAH | Diphthine synthase | / | 0.455 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.455 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.455 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.455 | |
| 3kru | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.455 | |
| 3zhb | NAP | Putative dehydrogenase | / | 0.455 | |
| 3zhs | TD6 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.455 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.455 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.455 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.455 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.455 | |
| 4y7c | FAD | NADPH--cytochrome P450 reductase | / | 0.455 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.455 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.454 | |
| 1jcq | 739 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.454 | |
| 1jdt | MTA | Purine nucleoside phosphorylase | / | 0.454 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.454 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.454 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.454 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.454 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.454 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.454 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.454 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.454 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.454 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.454 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.454 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.454 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.454 | |
| 3t64 | DU3 | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.454 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.454 | |
| 3wag | TYD | Glycosyltransferase | / | 0.454 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 4ddh | MS0 | Pantothenate synthetase | 6.3.2.1 | 0.454 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 4ejv | LCL | Transcriptional regulator TcaR | / | 0.454 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.454 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.454 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.454 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.454 | |
| 5a1t | NAI | L-lactate dehydrogenase | / | 0.454 | |
| 5af7 | FAD | Acyl-CoA dehydrogenase | / | 0.454 | |
| 1al8 | DHP | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.453 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.453 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.453 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.453 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.453 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.453 | |
| 2q3r | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.453 | |
| 2vou | FAD | 2,6-dihydroxypyridine 3-monooxygenase | 1.14.13.10 | 0.453 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.453 | |
| 3hgr | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.453 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.453 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.453 | |
| 3keu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.453 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.453 | |
| 3wv7 | ADP | Hmd co-occurring protein HcgE | / | 0.453 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.453 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.453 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.453 | |
| 4lrl | TTP | HD domain protein | / | 0.453 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.453 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.453 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.453 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 1jkx | 138 | Phosphoribosylglycinamide formyltransferase | / | 0.452 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.452 | |
| 1pmn | 984 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.452 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.452 | |
| 1zga | HMK | Isoflavone 4'-O-methyltransferase | / | 0.452 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.452 | |
| 2bf4 | FAD | NADPH--cytochrome P450 reductase | / | 0.452 | |
| 2nn7 | M29 | Carbonic anhydrase 1 | 4.2.1.1 | 0.452 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.452 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 0.452 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.452 | |
| 3eks | CY9 | Actin-5C | / | 0.452 | |
| 3ixk | 929 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.452 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.452 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.452 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.452 | |
| 3veu | 0GO | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.452 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.452 | |
| 4gxs | 0YS | Glutamate receptor 2 | / | 0.452 | |
| 4jau | ADP | Sensor histidine kinase | / | 0.452 | |
| 4nau | AGS | Phosphopantetheine adenylyltransferase | / | 0.452 | |
| 4ubv | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.452 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.452 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.451 | |
| 1obb | NAD | Alpha-glucosidase | 3.2.1.20 | 0.451 | |
| 1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.451 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.451 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.451 | |
| 2owg | SAH | Diphthine synthase | / | 0.451 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.451 | |
| 3ksq | Z96 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.451 | |
| 3mk6 | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.451 | |
| 3n0c | FAD | Flavin-dependent thymidylate synthase | 2.1.1.148 | 0.451 | |
| 3n19 | FNR | Xenobiotic reductase | / | 0.451 | |
| 3oix | FMN | Dihydroorotate dehydrogenase | / | 0.451 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.451 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.451 | |
| 4dja | FAD | (6-4) photolyase | / | 0.451 | |
| 4djy | 0KR | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.451 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.451 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4l5a | TBN | S-methyl-5'-thioadenosine phosphorylase | / | 0.451 | |
| 4na4 | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.451 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.451 | |
| 4z4p | SAH | Histone-lysine N-methyltransferase 2D | 2.1.1.43 | 0.451 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.450 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.450 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.450 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.450 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.450 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.450 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.450 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 2d8a | NAD | L-threonine 3-dehydrogenase | / | 0.450 | |
| 2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.450 | |
| 2j83 | BAT | Ulilysin | 3.4.24 | 0.450 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.450 | |
| 2oz5 | 7XY | Uncharacterized protein | / | 0.450 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.450 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.450 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 3bl7 | DD1 | m7GpppX diphosphatase | 3.6.1.59 | 0.450 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.450 | |
| 3lnb | COA | N-acetyltransferase family protein | / | 0.450 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.450 | |
| 3vgl | ANP | Glucokinase | / | 0.450 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.450 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.450 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.450 | |
| 4gdc | NDP | UDP-galactopyranose mutase | / | 0.450 | |
| 4ktf | 1TM | Cytochrome P450 | / | 0.450 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 5c77 | SAH | Protein arginine N-methyltransferase SFM1 | / | 0.450 | |
| 1ci0 | FMN | Pyridoxamine 5'-phosphate oxidase | 1.4.3.5 | 0.449 | |
| 1hdo | NAP | Flavin reductase (NADPH) | / | 0.449 | |
| 1l2t | ATP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.449 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.449 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.449 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.449 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.449 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.449 | |
| 2fgk | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.449 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.449 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.449 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.449 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.449 | |
| 3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.449 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.449 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.449 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 4a6b | QG8 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 4g2g | TDH | Mycocyclosin synthase | 1.14.21.9 | 0.449 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.449 | |
| 4hms | FMN | Phenazine biosynthesis protein PhzG | 1.4 | 0.449 | |
| 4j75 | TYM | Tryptophan--tRNA ligase | / | 0.449 | |
| 4rww | 2BA | Lmo2692 protein | / | 0.449 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 1ege | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.448 | |
| 1i0s | FMN | Ferric-chelate reductase (NAD(P)H) | / | 0.448 | |
| 1iqr | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.448 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.448 | |
| 1ld8 | U49 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.448 | |
| 1qpl | 587 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.448 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.448 | |
| 2dgn | DOI | Adenylosuccinate synthetase isozyme 1 | / | 0.448 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.448 | |
| 2fxf | ACO | Diamine acetyltransferase 1 | / | 0.448 | |
| 2g20 | L1A | Renin | 3.4.23.15 | 0.448 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.448 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.448 | |
| 2pam | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.448 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.448 | |
| 2vtd | LKM | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.448 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3a3g | DLZ | Lumazine protein | / | 0.448 | |
| 3e32 | ED2 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.448 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.448 | |
| 3fcj | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.448 | |
| 3hlw | CE3 | Beta-lactamase | / | 0.448 | |
| 3kpb | SAM | Uncharacterized protein MJ0100 | / | 0.448 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.448 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.448 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.448 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.448 | |
| 4opu | FDA | Conserved Archaeal protein | / | 0.448 | |
| 4rvf | TYD | D-mycarose 3-C-methyltransferase | / | 0.448 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.448 | |
| 4yal | 2AM | NADPH--cytochrome P450 reductase | / | 0.448 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA2 | 3.6.3 | 0.448 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA1 | / | 0.448 | |
| 5hg0 | SAM | Pantothenate synthetase | / | 0.448 | |
| 3uon | QNB | Muscarinic acetylcholine receptor M2 | / | 0.448 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 1fml | RTL | Retinol dehydratase | / | 0.447 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.447 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 2aou | CQA | Histamine N-methyltransferase | 2.1.1.8 | 0.447 | |
| 2ay9 | 5PV | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.447 | |
| 2bxm | IMN | Serum albumin | / | 0.447 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.447 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.447 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.447 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.447 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2p6k | SAH | Diphthine synthase | / | 0.447 | |
| 2vqo | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.447 | |
| 2x91 | LPR | Angiotensin-converting enzyme | 3.4.15.1 | 0.447 | |
| 2xfi | XFI | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.447 | |
| 2y65 | ADP | Kinesin heavy chain | / | 0.447 | |
| 2zsd | COA | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 3c16 | FOK | Adenylate cyclase type 2 | / | 0.447 | |
| 3c16 | FOK | Adenylate cyclase type 5 | / | 0.447 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.447 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.447 | |
| 3vye | VYE | Renin | 3.4.23.15 | 0.447 | |
| 4b0q | GMF | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4ef4 | C2E | Stimulator of interferon genes protein | / | 0.447 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.447 | |
| 4gtp | 7TP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.447 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.447 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.447 | |
| 4qoe | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.447 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.447 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.447 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.447 | |
| 1c6y | MK1 | Protease | / | 0.446 | |
| 1jdv | ADN | Purine nucleoside phosphorylase | / | 0.446 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.446 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.446 | |
| 1rb3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.446 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.446 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.446 | |
| 2b8l | 5HA | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.446 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.446 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 2wzw | NDP | Nitroreductase NfnB | / | 0.446 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.446 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.446 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.446 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3h2s | NDP | Putative NADH-flavin reductase | / | 0.446 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.446 | |
| 3jyq | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.446 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.446 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.446 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4uth | FMN | Xenobiotic reductase | / | 0.446 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.446 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.446 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.446 | |
| 4djh | JDC | Kappa-type opioid receptor | / | 0.446 | |
| 1h61 | PDN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.445 | |
| 1ja0 | FAD | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.445 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.445 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.445 | |
| 1q83 | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.445 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2anb | 5GP | Guanylate kinase | 2.7.4.8 | 0.445 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.445 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.445 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.445 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.445 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.445 | |
| 2xb5 | I7T | Tetracycline repressor protein class D | / | 0.445 | |
| 2xfs | J01 | Uncharacterized protein | / | 0.445 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.445 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.445 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.445 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.445 | |
| 3tif | ADP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.445 | |
| 3uk6 | ADP | RuvB-like 2 | 3.6.4.12 | 0.445 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.445 | |
| 3zhu | TD8 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.445 | |
| 3zxs | FAD | Deoxyribodipyrimidine photolyase-related protein | / | 0.445 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.445 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.445 | |
| 4m5p | FMN | NADPH dehydrogenase | / | 0.445 | |
| 4rxp | DTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.445 | |
| 4yaw | 2AM | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.444 | |
| 1n2h | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.444 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.444 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.444 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.444 | |
| 2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.444 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.444 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.444 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.444 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.444 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.444 | |
| 2x19 | GTP | GTP-binding nuclear protein GSP1/CNR1 | / | 0.444 | |
| 2x8g | FAD | Thioredoxin glutathione reductase | / | 0.444 | |
| 2xtz | GSP | Guanine nucleotide-binding protein alpha-1 subunit | / | 0.444 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.444 | |
| 3ccc | 7AC | Dipeptidyl peptidase 4 | / | 0.444 | |
| 3gnv | XNZ | Genome polyprotein | 2.7.7.48 | 0.444 | |
| 3hyg | 099 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.444 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.444 | |
| 3mdd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.444 | |
| 4blr | UTP | NTPase P4 | / | 0.444 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.444 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.444 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.444 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.444 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.444 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.443 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.443 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.443 | |
| 1gqt | ACP | Ribokinase | / | 0.443 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1iki | REY | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.443 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.443 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.443 | |
| 1pag | FMP | Antiviral protein I | 3.2.2.22 | 0.443 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.443 | |
| 2b4r | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.443 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.443 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.443 | |
| 2ok7 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.443 | |
| 2uuv | FAD | Alkyldihydroxyacetonephosphate synthase | 2.5.1.26 | 0.443 | |
| 2uzf | CAA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.443 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2z1m | NDP | GDP-mannose 4,6-dehydratase | / | 0.443 | |
| 3b9l | AZZ | Serum albumin | / | 0.443 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3ivm | ZPR | Prolyl endopeptidase | / | 0.443 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.443 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.443 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4asu | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.443 | |
| 4e2d | FMN | Dehydrogenase | / | 0.443 | |
| 4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.443 | |
| 4i9n | 1E5 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.443 | |
| 4jbs | P52 | Endoplasmic reticulum aminopeptidase 2 | 3.4.11 | 0.443 | |
| 4jxr | ACO | Acetyltransferase | / | 0.443 | |
| 4ke0 | 1R8 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.443 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.443 | |
| 5ao1 | DG3 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.443 | |
| 5dp2 | NAP | CurF | / | 0.443 | |
| 1dgm | ADN | Adenosine kinase | 2.7.1.20 | 0.442 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.442 | |
| 1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1k4m | NAD | Nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.442 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.442 | |
| 1mbb | EEB | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.442 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1p31 | EPU | UDP-N-acetylmuramate--L-alanine ligase | 6.3.2.8 | 0.442 | |
| 1ppj | ANY | Cytochrome b | / | 0.442 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.442 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.442 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.442 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.442 | |
| 2g5c | NAD | Prephenate dehydrogenase | / | 0.442 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.442 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 2pj4 | 414 | Carboxypeptidase B | / | 0.442 | |
| 2r7p | ANP | Non-structural protein 2 | 3.6.4 | 0.442 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.442 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.442 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.442 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.442 | |
| 3s87 | ADP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.442 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.442 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.442 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.442 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.442 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.442 | |
| 4oe4 | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.442 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.442 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.442 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.442 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.442 | |
| 4x7v | MIV | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.442 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.442 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.441 | |
| 1lke | DOG | Bilin-binding protein | / | 0.441 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.441 | |
| 2clf | F6F | Tryptophan synthase alpha chain | / | 0.441 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.441 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.441 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2hu2 | NAD | C-terminal binding protein 1 | / | 0.441 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2irz | I02 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2owf | SAH | Diphthine synthase | / | 0.441 | |
| 2vqb | FAD | Putative flavin-containing monooxygenase | / | 0.441 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.441 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
| 3ixj | 586 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3n0b | FAD | Flavin-dependent thymidylate synthase | 2.1.1.148 | 0.441 | |
| 3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 3owa | FAD | Acyl-CoA dehydrogenase | / | 0.441 | |
| 3ox4 | NAD | Alcohol dehydrogenase 2 | 1.1.1.1 | 0.441 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.441 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.441 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4kug | NAD | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.441 | |
| 4mkh | AP5 | Adenylate kinase | / | 0.441 | |
| 4tqg | NDP | Putative dTDP-d-glucose 4 6-dehydratase | / | 0.441 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 4y7c | NAP | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 4zvn | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.441 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1gal | FAD | Glucose oxidase | 1.1.3.4 | 0.440 | |
| 1ja0 | FMN | NADPH--cytochrome P450 reductase | / | 0.440 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.440 | |
| 2b3v | ACO | Diamine acetyltransferase 1 | / | 0.440 | |
| 2bac | FAD | Putative aminooxidase | / | 0.440 | |
| 2c2a | ADP | Sensor histidine kinase | / | 0.440 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.440 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.440 | |
| 3mj4 | URM | UDP-galactopyranose mutase | / | 0.440 | |
| 3n14 | FMN | Xenobiotic reductase | / | 0.440 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.440 | |
| 3qfa | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.440 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.440 | |
| 3qgi | 33F | Genome polyprotein | 2.7.7.48 | 0.440 | |
| 3r95 | ACO | MccE protein | / | 0.440 | |
| 3ty3 | GGG | Homoisocitrate dehydrogenase | 1.1.1.87 | 0.440 | |
| 4b65 | FAD | L-ornithine N(5)-monooxygenase | / | 0.440 | |
| 4bqz | GNP | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.440 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.440 | |
| 4k36 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.440 | |
| 4lcg | 1WM | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.440 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 | |
| 5fl3 | ADP | Pili retraction protein PilT | / | 0.440 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.440 |