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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4a7cE46Serine/threonine-protein kinase pim-12.7.11.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4a7cE46Serine/threonine-protein kinase pim-12.7.11.11.000
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.687
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.672
5dgzL20Serine/threonine-protein kinase pim-12.7.11.10.668
2xizXIZSerine/threonine-protein kinase pim-12.7.11.10.663
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.661
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.660
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.658
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.655
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.654
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.650
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.645
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.643
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.640
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.636
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.635
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.632
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.632
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.632
3dcv55ESerine/threonine-protein kinase pim-12.7.11.10.630
2bilBI1Serine/threonine-protein kinase pim-12.7.11.10.629
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.625
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.624
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.623
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.622
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.621
4i41MIXSerine/threonine-protein kinase pim-12.7.11.10.619
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.618
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.617
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.616
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.616
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.616
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.612
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.606
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.596
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.595
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.591
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.585
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.585
3umw596Serine/threonine-protein kinase pim-12.7.11.10.585
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.584
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.580
2xiyXIYSerine/threonine-protein kinase pim-12.7.11.10.578
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.577
2xj2985Serine/threonine-protein kinase pim-12.7.11.10.575
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.568
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.566
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.560
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.558
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.556
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.549
3iw4LW4Protein kinase C alpha type2.7.11.130.543
4wboANWRhodopsin kinase/0.543
2jedLG8Protein kinase C theta type2.7.11.130.536
4gw83RASerine/threonine-protein kinase pim-12.7.11.10.531
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.529
4i22IREEpidermal growth factor receptor2.7.10.10.529
3nga3NGCasein kinase II subunit alpha2.7.11.10.526
3du8553Glycogen synthase kinase-3 beta2.7.11.260.525
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.525
4c02TAKActivin receptor type-12.7.11.300.524
1q1rFADPutidaredoxin reductase1.18.1.50.522
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.521
1xjdSTUProtein kinase C theta type2.7.11.130.521
3oom507Activin receptor type-12.7.11.300.520
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.517
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.515
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.515
3vf9477Tyrosine-protein kinase SYK2.7.10.20.515
3q9xEMOCasein kinase II subunit alpha2.7.11.10.514
5cvhADPCasein kinase II subunit alpha2.7.11.10.513
1zys199Serine/threonine-protein kinase Chk12.7.11.10.511
2chlDKICasein kinase I isoform gamma-32.7.11.10.511
4grb0XGCasein kinase II subunit alpha2.7.11.10.511
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.510
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.510
4yuqKS1Calmodulin-like domain protein kinase/0.510
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.509
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.508
4othDRNSerine/threonine-protein kinase N1/0.508
3et7349Protein-tyrosine kinase 2-beta2.7.10.20.507
4dymIYZActivin receptor type-12.7.11.300.507
2itpAEEEpidermal growth factor receptor2.7.10.10.506
4gg70J8Hepatocyte growth factor receptor2.7.10.10.506
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.504
3mtfA3FActivin receptor type-12.7.11.300.504
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.504
5av2KMPDeath-associated protein kinase 12.7.11.10.504
1u54ACPActivated CDC42 kinase 1/0.503
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.503
2itqITQEpidermal growth factor receptor2.7.10.10.503
2ittAEEEpidermal growth factor receptor2.7.10.10.503
3a4pDFQHepatocyte growth factor receptor2.7.10.10.503
4jq8KJ8Epidermal growth factor receptor2.7.10.10.503
3u4uLNHCasein kinase II subunit alpha2.7.11.10.502
4bchT7ZCyclin-dependent kinase 92.7.11.220.502
3pe2E1BCasein kinase II subunit alpha2.7.11.10.501
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.501
3uyt0CKCasein kinase I isoform delta2.7.11.10.501
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.500
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.500
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.500
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.499
4g170VNCasein kinase I isoform gamma-32.7.11.10.499
5auwQUEDeath-associated protein kinase 12.7.11.10.499
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.498
4bgg844Activin receptor type-12.7.11.300.498
2j0k4STFocal adhesion kinase 12.7.10.20.497
4hni16WCasein kinase I isoform epsilon2.7.11.10.497
1klkPMDDihydrofolate reductase1.5.1.30.496
2hog710Serine/threonine-protein kinase Chk12.7.11.10.496
3bqr4RBDeath-associated protein kinase 3/0.496
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.495
1wvxBD4Death-associated protein kinase 12.7.11.10.495
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.495
2wihP48Cyclin-dependent kinase 22.7.11.220.495
2bujSTUSerine/threonine-protein kinase 16/0.494
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.494
5auxKMPDeath-associated protein kinase 12.7.11.10.494
1h1s4SPCyclin-dependent kinase 22.7.11.220.493
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.493
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.493
3blrCPBCyclin-dependent kinase 92.7.11.220.493
3fzr3JZProtein-tyrosine kinase 2-beta2.7.10.20.493
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.493
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.493
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.492
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.492
2x1nX1NCyclin-dependent kinase 22.7.11.220.492
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.492
4neuQ1AReceptor-interacting serine/threonine-protein kinase 12.7.11.10.492
1d2sDHTSex hormone-binding globulin/0.491
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.491
3sheI85MAP kinase-activated protein kinase 32.7.11.10.491
3zze6XPHepatocyte growth factor receptor2.7.10.10.491
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.491
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.491
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.491
4jrvKJVEpidermal growth factor receptor2.7.10.10.491
1n4hREANuclear receptor ROR-beta/0.490
1s3wTQTDihydrofolate reductase1.5.1.30.490
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.490
2etm7PYFocal adhesion kinase 12.7.10.20.490
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.490
4foc0UUALK tyrosine kinase receptor2.7.10.10.490
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.489
1og5SWFCytochrome P450 2C9/0.489
2ckeIQUDeath-associated protein kinase 2/0.489
2uxpCLMHTH-type transcriptional regulator TtgR/0.489
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.489
3at4CCKCasein kinase II subunit alpha2.7.11.10.489
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.489
4b7tCWTGlycogen synthase kinase-3 beta2.7.11.260.489
4gg50J3Hepatocyte growth factor receptor2.7.10.10.489
4i4e1BQFocal adhesion kinase 12.7.10.20.489
4wa9AXITyrosine-protein kinase ABL12.7.10.20.489
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.488
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.488
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.488
3gc9B45Mitogen-activated protein kinase 112.7.11.240.488
3vetADPnebramycin 5' synthase6.1.2.20.488
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.488
4gu610NFocal adhesion kinase 12.7.10.20.488
5av3KMPDeath-associated protein kinase 12.7.11.10.488
5cu6ATPCasein kinase II subunit alpha2.7.11.10.488
2vagV25Dual specificity protein kinase CLK12.7.12.10.487
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.487
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.487
4kbk1QGCasein kinase I isoform delta2.7.11.10.487
5auvAGIDeath-associated protein kinase 12.7.11.10.487
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.486
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.486
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.486
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.486
4hnf16WCasein kinase I isoform delta2.7.11.10.486
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.485
2j5xGSPADP-ribosylation factor 6/0.485
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.485
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.485
4fob0USALK tyrosine kinase receptor2.7.10.10.485
4fz60VGTyrosine-protein kinase SYK2.7.10.20.485
4gmy0X5Tyrosine-protein kinase JAK2/0.485
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.485
1m17AQ4Epidermal growth factor receptor2.7.10.10.484
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.484
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.484
3l9nL9NcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.484
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.484
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.483
3c1xCKKHepatocyte growth factor receptor2.7.10.10.483
3sd0TSKGlycogen synthase kinase-3 beta2.7.11.260.483
3vt9YI4Vitamin D3 receptor/0.483
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.483
4g160VMCasein kinase I isoform gamma-32.7.11.10.483
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.483
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.483
5f0a1FBcGMP-dependent protein kinase, putative/0.483
1e9hINRCyclin-dependent kinase 22.7.11.220.482
2wkmPFYHepatocyte growth factor receptor2.7.10.10.482
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.482
4o0wADNAurora kinase A2.7.11.10.482
1t1rIMB1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.481
3kf7L9GMitogen-activated protein kinase 14/0.481
3q3b55EGlycogen synthase kinase-3 beta2.7.11.260.481
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.481
4iarERM5-hydroxytryptamine receptor 1B/0.481
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.481
1fpqSAMIsoliquiritigenin 2'-O-methyltransferase/0.480
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.480
2iw84SPCyclin-dependent kinase 22.7.11.220.480
2jkoBIJFocal adhesion kinase 12.7.10.20.480
3fzpAGSProtein-tyrosine kinase 2-beta2.7.10.20.480
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.480
1bxoPP7Penicillopepsin-13.4.23.200.479
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.479
1eh4IC1Casein kinase I homolog 12.7.11.10.479
1ouk084Mitogen-activated protein kinase 14/0.479
1rt4UC1Gag-Pol polyprotein2.7.7.490.479
2xikJ60Serine/threonine-protein kinase 252.7.11.10.479
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.479
3gubGUBDeath-associated protein kinase 12.7.11.10.479
3k47D09Dihydrofolate reductase1.5.1.30.479
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.479
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.479
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.479
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.479
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.479
4h9506UDihydrofolate reductase1.5.1.30.479
1ywrLI9Mitogen-activated protein kinase 14/0.478
1zrzBI1Protein kinase C iota type2.7.11.130.478
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.478
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.478
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.478
3igoANPCalmodulin-domain protein kinase 1, putative/0.478
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.478
3r3b4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.478
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.478
4eon1ROCyclin-dependent kinase 22.7.11.220.478
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.478
4nb6444Nuclear receptor ROR-gamma/0.478
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.478
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.477
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.477
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.477
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.477
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.477
2xyuQ9GEphrin type-A receptor 42.7.10.10.477
2zjwREFCasein kinase II subunit alpha2.7.11.10.477
3qlxQLRUncharacterized protein/0.477
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.477
4jq7KJQEpidermal growth factor receptor2.7.10.10.477
4l455FIRibosomal protein S6 kinase beta-12.7.11.10.477
4nc3ERM5-hydroxytryptamine receptor 2B/0.477
4qmzB49Serine/threonine-protein kinase 242.7.11.10.477
4riyADPEpidermal growth factor receptor2.7.10.10.477
1zgaHMKIsoflavone 4'-O-methyltransferase/0.476
2cchATPCyclin-dependent kinase 22.7.11.220.476
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.476
3r324CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.476
3th8TH9Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.476
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.476
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.476
4gub0Y4Casein kinase II subunit alpha2.7.11.10.476
2gr1FADFerredoxin reductase/0.475
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.475
3cquCQURAC-alpha serine/threonine-protein kinase2.7.11.10.475
3efwAK8Aurora kinase A2.7.11.10.475
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.475
4bcoT6QCyclin-dependent kinase 22.7.11.220.475
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.475
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.475
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.475
1bygSTUTyrosine-protein kinase CSK/0.474
1i7iAZ2Peroxisome proliferator-activated receptor gamma/0.474
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.474
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.474
2q9fC3SCholesterol 24-hydroxylase/0.474
3ictFADCoenzyme A disulfide reductase/0.474
4eh9IRGMitogen-activated protein kinase 14/0.474
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.474
4ienCOAPutative acyl-CoA hydrolase/0.474
4tzt468Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.474
1bozPRDDihydrofolate reductase1.5.1.30.473
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.473
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.473
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.473
3ddqRRCCyclin-dependent kinase 22.7.11.220.473
3eek53SUncharacterized protein/0.473
3t8oATPRhodopsin kinase/0.473
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.473
4hgt15GCasein kinase I isoform delta2.7.11.10.473
4jqeANPCasein kinase II subunit alpha2.7.11.10.473
4tzk641Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.473
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.472
2pywADPMethylthioribose kinase2.7.1.1000.472
3ddpRC8Cyclin-dependent kinase 22.7.11.220.472
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.472
3irn1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.472
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.472
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.472
3owl19ECasein kinase II subunit alpha2.7.11.10.472
3r0tFU9Casein kinase II subunit alpha2.7.11.10.472
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.472
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.472
4bqpVMYEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.472
4h9814QUncharacterized protein/0.472
4i0t1B6Tyrosine-protein kinase SYK2.7.10.20.472
4ixgIXGDihydrofolate reductase1.5.1.30.472
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.472
4jwr1MYE3 ubiquitin-protein ligase Mdm26.3.20.472
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.472
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.472
4pv5CBWLactoylglutathione lyase4.4.1.50.472
5bmvVLBTubulin alpha-1B chain/0.472
5bmvVLBTubulin beta chain/0.472
1fp2HMOIsoflavone-7-O-methyltransferase 82.1.1.1500.471
1jklANPDeath-associated protein kinase 12.7.11.10.471
1qiwDPDCalmodulin/0.471
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.471
2i0ePDSProtein kinase C beta type2.7.11.130.471
3a62STURibosomal protein S6 kinase beta-12.7.11.10.471
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.471
3rg9WRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.471
4c4jX21Dual specificity protein kinase TTK2.7.12.10.471
4erwSTUCyclin-dependent kinase 22.7.11.220.471
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.471
4jr3KJREpidermal growth factor receptor2.7.10.10.471
4k8aK8AFocal adhesion kinase 12.7.10.20.471
1m7aMQUDihydrofolate reductase1.5.1.30.470
1qxlFR8Adenosine deaminase3.5.4.40.470
1revTB9Gag-Pol polyprotein2.7.7.490.470
1s9qOHTEstrogen-related receptor gamma/0.470
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.470
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.470
4e730NRMitogen-activated protein kinase 82.7.11.240.470
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.470
4ib4ERM5-hydroxytryptamine receptor 2B/0.470
4qmySTUSerine/threonine-protein kinase 242.7.11.10.470
5cshATPCasein kinase II subunit alpha2.7.11.10.470
3uzcT4EAdenosine receptor A2a/0.470
1bvrTHTEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.469
1dz6CAMCamphor 5-monooxygenase1.14.15.10.469
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.469
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.469
2b55D31Cyclin-dependent kinase 22.7.11.220.469
2w1fL0FAurora kinase A2.7.11.10.469
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.469
3c50ADPRhodopsin kinase/0.469
3i8aN22Dihydrofolate reductase1.5.1.30.469
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.469
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.469
3tea4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.469
3zep1NXTyrosine-protein kinase JAK32.7.10.20.469
3zh8C58Protein kinase C iota type2.7.11.130.469
4bcqTJFCyclin-dependent kinase 22.7.11.220.469
4ixfIXFDihydrofolate reductase1.5.1.30.469
3emlZMAAdenosine receptor A2a/0.469
1lhvNOGSex hormone-binding globulin/0.468
2bzsCB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.468
2j0j4STFocal adhesion kinase 12.7.10.20.468
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.468
3le62BZCyclin-dependent kinase 22.7.11.220.468
3s7a684Dihydrofolate reductase1.5.1.30.468
4kb81QNCasein kinase I isoform delta2.7.11.10.468
4wkqIREEpidermal growth factor receptor2.7.10.10.468
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.467
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.467
1u4dDBQActivated CDC42 kinase 1/0.467
1x2hLPALipoate-protein ligase A6.3.1.200.467
2c475IDCasein kinase I isoform gamma-2/0.467
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.467
2yfeYFEPeroxisome proliferator-activated receptor gamma/0.467
2zva1N1Tyrosine-protein kinase Lyn2.7.10.20.467
3rni21ZCyclin-dependent kinase 22.7.11.220.467
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.467
3um61CYBifunctional dihydrofolate reductase-thymidylate synthase/0.467
3wowANPCasein kinase II subunit alpha2.7.11.10.467
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.467
4ek610KCyclin-dependent kinase 22.7.11.220.467
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.467
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.467
4hnc0UTMandelate racemase/0.467
4hyu1BKMitogen-activated protein kinase 82.7.11.240.467
4iaq2GM5-hydroxytryptamine receptor 1B/0.467
5av4GENDeath-associated protein kinase 12.7.11.10.467
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.466
1enyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.466
1h1r6CPCyclin-dependent kinase 22.7.11.220.466
1ouy094Mitogen-activated protein kinase 14/0.466
1tqmANPRIO-type serine/threonine-protein kinase Rio22.7.11.10.466
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.466
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.466
2duv371Cyclin-dependent kinase 22.7.11.220.466
2x6dX6DAurora kinase A2.7.11.10.466
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.466
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.466
3pm0BHFCytochrome P450 1B1/0.466
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.466
3vsoEK1Peroxisome proliferator-activated receptor gamma/0.466
4c4h7RODual specificity protein kinase TTK2.7.12.10.466
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.466
4k9yK9YFocal adhesion kinase 12.7.10.20.466
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.466
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.466
1hfpMOTDihydrofolate reductase1.5.1.30.465
1l2jETCEstrogen receptor beta/0.465
1oiuN76Cyclin-dependent kinase 22.7.11.220.465
1oiyN41Cyclin-dependent kinase 22.7.11.220.465
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.465
1uyrD1LAcetyl-CoA carboxylase/0.465
2a0cCK9Cyclin-dependent kinase 22.7.11.220.465
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.465
2g2hP16Tyrosine-protein kinase ABL12.7.10.20.465
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.465
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.465
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.465
2z7gEH9Adenosine deaminase3.5.4.40.465
3dgaRJ1Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.465
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
3zrkZRKGlycogen synthase kinase-3 beta2.7.11.260.465
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.465
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.465
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.465
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.465
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.465
5ai5BSUBifunctional epoxide hydrolase 23.1.3.760.465
5cvfATPCasein kinase II subunit alpha2.7.11.10.465
1phgMYTCamphor 5-monooxygenase1.14.15.10.464
2b52D42Cyclin-dependent kinase 22.7.11.220.464
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.464
2ijmADPFocal adhesion kinase 12.7.10.20.464
2olcADPMethylthioribose kinase2.7.1.1000.464
2puiADPMethylthioribose kinase2.7.1.1000.464
2qblCAMCamphor 5-monooxygenase1.14.15.10.464
2qmzLDPRibosyldihydronicotinamide dehydrogenase [quinone]/0.464
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.464
3a60STURibosomal protein S6 kinase beta-12.7.11.10.464
3cv9VDXVitamin D3 dihydroxylase/0.464
3och2MXDihydrofolate reductase1.5.1.30.464
3owk18ECasein kinase II subunit alpha2.7.11.10.464
3sgx0FWDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.464
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.464
4eor4SPCyclin-dependent kinase 22.7.11.220.464
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.464
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.464
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.464
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.464
4nh82LCHeat shock protein HSP 90-alpha/0.464
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.464
5e8wSTUTGF-beta receptor type-12.7.11.300.464
1mb9ATPCarboxyethyl-arginine beta-lactam-synthase6.3.3.40.463
2aqiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.463
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.463
2csnCKICasein kinase I homolog 12.7.11.10.463
2izuP01Casein kinase I isoform gamma-32.7.11.10.463
2vzmNRBCytochrome P450 monooxygenase PikC/0.463
3bu5ATPInsulin receptor2.7.10.10.463
3f883HTGlycogen synthase kinase-3 beta2.7.11.260.463
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.463
3nglNAPBifunctional protein FolD/0.463
3qa2XNAKetohexokinase/0.463
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.463
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.463
4em9TCEPeroxisome proliferator-activated receptor gamma/0.463
4fex0TOAminoglycoside 3'-phosphotransferase AphA1-IAB/0.463
4fhj0TZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
4kak06UDihydrofolate reductase1.5.1.30.463
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.463
4pkl1GHUncharacterized protein/0.463
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.463
4ubsDIFPentalenic acid synthase1.14.15.110.463
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.463
5auzGENDeath-associated protein kinase 12.7.11.10.463
1dkfBMSRetinoic acid receptor alpha/0.462
1q4t4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.462
1zhwHC2Oxysterol-binding protein homolog 4/0.462
2c7xNRBCytochrome P450 monooxygenase PikC/0.462
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
2j0lANPFocal adhesion kinase 12.7.10.20.462
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.462
2z97CAMCamphor 5-monooxygenase1.14.15.10.462
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
3m8qDJZGag-Pol polyprotein2.7.7.490.462
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.462
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.462
3r3f4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.462
3srwQ27Dihydrofolate reductase1.5.1.30.462
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.462
4deg0JJHepatocyte growth factor receptor2.7.10.10.462
4ejh0QACytochrome P450 2A131.14.14.10.462
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.462
4ic7ANPMitogen-activated protein kinase 72.7.11.240.462
4o0sADNAurora kinase A2.7.11.10.462
5cccDDFDihydrofolate reductase1.5.1.30.462
1lhwESMSex hormone-binding globulin/0.461
1rt5UC2Gag-Pol polyprotein2.7.7.490.461
1rx3MTXDihydrofolate reductase1.5.1.30.461
1rx5DDFDihydrofolate reductase1.5.1.30.461
2izt23DCasein kinase I isoform gamma-32.7.11.10.461
2x7f824TRAF2 and NCK-interacting protein kinase2.7.11.10.461
3axwTIDCasein kinase II subunit alpha2.7.11.10.461
3c4xATPRhodopsin kinase/0.461
3el8PD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.461
3gxlQIGTGF-beta receptor type-12.7.11.300.461
3i81EBIInsulin-like growth factor 1 receptor2.7.10.10.461
3ibeL64Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.461
3pre3REPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
3q9zTXQCasein kinase II subunit alpha2.7.11.10.461
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.461
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.461
3qfxCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.461
3qgtCP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.461
3qtzX42Cyclin-dependent kinase 22.7.11.220.461
3rpo24ZCyclin-dependent kinase 22.7.11.220.461
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.461
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.461
4f7l0SOCyclin-dependent kinase 82.7.11.220.461
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.461
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.461
4gfg0XFTyrosine-protein kinase SYK2.7.10.20.461
4ix6ADPUncharacterized protein/0.461
4jbpYPHAurora kinase A2.7.11.10.461
5auuLU2Death-associated protein kinase 12.7.11.10.461
5dt4ATPAurora kinase A2.7.11.10.461
1lp4ANPCasein kinase II subunit alpha2.7.11.10.460
1uuoBRFDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.460
1zaoATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.460
1zidZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.460
2bheBRYCyclin-dependent kinase 22.7.11.220.460
2izsBRQCasein kinase I isoform gamma-32.7.11.10.460
2pmnK51Protein kinase 7/0.460
2uzlC94Cyclin-dependent kinase 22.7.11.220.460
2wpa889Cyclin-dependent kinase 22.7.11.220.460
2xh9J01Uncharacterized protein/0.460
2y4mGDXUncharacterized protein/0.460
3cinNADMyo-inositol-1-phosphate synthase-related protein/0.460
3gwfFADCyclohexanone monooxygenase/0.460
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.460
3opdHIEHeat shock protein 83/0.460
3poz03PEpidermal growth factor receptor2.7.10.10.460
3r354CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.460
3vewADPnebramycin 5' synthase6.1.2.20.460
3vt7VDXVitamin D3 receptor/0.460
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.460
4bdiHAUSerine/threonine-protein kinase Chk22.7.11.10.460
4c62XWWTyrosine-protein kinase JAK2/0.460
4f1sF1SPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
4fyn0VETyrosine-protein kinase SYK2.7.10.20.460
4hvg19QTyrosine-protein kinase JAK32.7.10.20.460
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.460
4jv81M1Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.460
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.460
4l98LRGPeroxisome proliferator-activated receptor gamma/0.460
5e8xSTUTGF-beta receptor type-12.7.11.300.460
1aoeGW3Dihydrofolate reductase1.5.1.30.459
1kl2FONSerine hydroxymethyltransferase/0.459
1ludTRRDihydrofolate reductase1.5.1.30.459
1tl1H18Gag-Pol polyprotein2.7.7.490.459
1tsxUMPThymidylate synthase/0.459
2acxANPG protein-coupled receptor kinase 62.7.11.160.459
2jkqVG8Focal adhesion kinase 12.7.10.20.459
2p33J07Mitogen-activated protein kinase 102.7.11.240.459
2vrbNAPTriphenylmethane reductase/0.459
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.459
2zmd537Dual specificity protein kinase TTK2.7.12.10.459
3c7qXINVascular endothelial growth factor receptor 22.7.10.10.459
3fi3JK2Mitogen-activated protein kinase 102.7.11.240.459
3mtlFEFCyclin-dependent kinase 162.7.11.220.459
3oqkS52Renin3.4.23.150.459
3rpv26ZCyclin-dependent kinase 22.7.11.220.459
3zxtACPDeath-associated protein kinase 12.7.11.10.459
4anmWULCasein kinase II subunit alpha2.7.11.10.459
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.459
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.459
4erkOLOMitogen-activated protein kinase 12.7.11.240.459
4g8zTOPDihydrofolate reductase1.5.1.30.459
4ig3T27Gag-Pol polyprotein2.7.7.490.459
4mcv29KProto-oncogene tyrosine-protein kinase Src2.7.10.20.459
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.459
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.459
1aq1STUCyclin-dependent kinase 22.7.11.220.458
1g5sI17Cyclin-dependent kinase 22.7.11.220.458
1jioDEB6-deoxyerythronolide B hydroxylase/0.458
1oguST8Cyclin-dependent kinase 22.7.11.220.458
1s1wUC1Gag-Pol polyprotein2.7.7.490.458
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.458
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.458
2cn8DBQSerine/threonine-protein kinase Chk22.7.11.10.458
2fzhDH1Dihydrofolate reductase1.5.1.30.458
2i40BLZCyclin-dependent kinase 22.7.11.220.458
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.458
3eyaTDPPyruvate dehydrogenase [ubiquinone]1.2.5.10.458
3gu6ADPDeath-associated protein kinase 12.7.11.10.458
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.458
3qg2CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.458
3ua506XCytochrome P450 2B61.14.130.458
4bi1ZO6Dual specificity protein kinase TTK2.7.12.10.458
4brxKGWFocal adhesion kinase 12.7.10.20.458
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
4ejgNCTCytochrome P450 2A131.14.14.10.458
4h9614QDihydrofolate reductase1.5.1.30.458
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
5dn3ATPAurora kinase A2.7.11.10.458
5drdATPAurora kinase A2.7.11.10.458
1bwsNDPGDP-L-fucose synthase/0.457
1cqp803Integrin alpha-L/0.457
1h1q2A6Cyclin-dependent kinase 22.7.11.220.457
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.457
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.457
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.457
1rx8NAPDihydrofolate reductase1.5.1.30.457
2dfdNADMalate dehydrogenase, mitochondrial1.1.1.370.457
2izrBRKCasein kinase I isoform gamma-32.7.11.10.457
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.457
2wgjVGHHepatocyte growth factor receptor2.7.10.10.457
2xnbY8LCyclin-dependent kinase 22.7.11.220.457
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.457
3anlNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.457
3bhy7CPDeath-associated protein kinase 3/0.457
3eem53VUncharacterized protein/0.457
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.457
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.457
3p23ADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.457
3zbx6XEHepatocyte growth factor receptor2.7.10.10.457
4deaNHIAurora kinase A2.7.11.10.457
4dp3MMVBifunctional dihydrofolate reductase-thymidylate synthase/0.457
4dscA8SAbscisic acid receptor PYL3/0.457
4e6a0O9Mitogen-activated protein kinase 14/0.457
4ewqMWLMitogen-activated protein kinase 14/0.457
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.457
4ful0VUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4hfmNAP2-alkenal reductase (NADP(+)-dependent)/0.457
4j1rI5RGlycogen synthase kinase-3 beta2.7.11.260.457
4yx6FMNOmega-3 polyunsaturated fatty acid synthase subunit PfaD/0.457
1kkq471Peroxisome proliferator-activated receptor alpha/0.456
1mq4ADPAurora kinase A2.7.11.10.456
1oi9N20Cyclin-dependent kinase 22.7.11.220.456
1pkdUCNCyclin-dependent kinase 22.7.11.220.456
1ppm0P1Penicillopepsin-13.4.23.200.456
1q4u4CA4-hydroxybenzoyl-CoA thioesterase3.1.2.230.456
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.456
2acwUPGGlycosyltransferase/0.456
2gpvOHTEstrogen-related receptor gamma/0.456
2hnzPC0Gag-Pol polyprotein2.7.7.490.456
2j4z626Aurora kinase A2.7.11.10.456
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.456
2r64740Cyclin-dependent kinase 22.7.11.220.456
2xb7GUIALK tyrosine kinase receptor2.7.10.10.456
3at3ATKCasein kinase II subunit alpha2.7.11.10.456
3bhtMFRCyclin-dependent kinase 22.7.11.220.456
3eej53RUncharacterized protein/0.456
3qaiXNNKetohexokinase/0.456
3qlrQLRDihydrofolate reductase1.5.1.30.456
3r336MEDihydrofolate reductase1.5.1.30.456
3tm0ANPAminoglycoside 3'-phosphotransferase2.7.1.950.456
3upyFOMOxidoreductase, putative/0.456
3uvp048Mitogen-activated protein kinase 14/0.456
4dgo0JWCasein kinase II subunit alpha2.7.11.10.456
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.456
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.456
4g1qT27Gag-Pol polyprotein2.7.7.490.456
4gu94GUFocal adhesion kinase 12.7.10.20.456
4ie5MD6Alpha-ketoglutarate-dependent dioxygenase FTO/0.456
1k749CRRetinoic acid receptor RXR-alpha/0.455
2bkkADPAminoglycoside 3'-phosphotransferase2.7.1.950.455
2ghmLICMitogen-activated protein kinase 14/0.455
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.455
2idzZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
2of2547Tyrosine-protein kinase Lck2.7.10.20.455
2pulACPMethylthioribose kinase2.7.1.1000.455
2pvjP44Casein kinase II subunit alpha2.7.11.10.455
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.455
2wxvWXVCyclin-dependent kinase 22.7.11.220.455
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.455
3a7hATPSerine/threonine-protein kinase 242.7.11.10.455
3fmjFMJMitogen-activated protein kinase 14/0.455
3fwjCAMCamphor 5-monooxygenase1.14.15.10.455
3gbk2PQPeroxisome proliferator-activated receptor gamma/0.455
3mdvCL6Cholesterol 24-hydroxylase/0.455
3nhwZXZRibosyldihydronicotinamide dehydrogenase [quinone]/0.455
3pj8404Cyclin-dependent kinase 22.7.11.220.455
3uxyNADShort-chain dehydrogenase/reductase SDR/0.455
3vg9ZMAAdenosine receptor A2a/0.455
3vrwYS5Vitamin D3 receptor/0.455
4a95NHWGlycylpeptide N-tetradecanoyltransferase/0.455
4acm7YGCyclin-dependent kinase 22.7.11.220.455
4azwATPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.455
4dgnLU2Casein kinase II subunit alpha2.7.11.10.455
4f4p0SBTyrosine-protein kinase SYK2.7.10.20.455
4haiI23Bifunctional epoxide hydrolase 23.1.3.760.455
4l0qNADAlcohol dehydrogenase class-3/0.455
4l4cCAMCamphor 5-monooxygenase1.14.15.10.455
4xumIMNPeroxisome proliferator-activated receptor gamma/0.455
4yduADPtRNA N6-adenosine threonylcarbamoyltransferase/0.455
1d3gBREDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.454
1e7aPFLSerum albumin/0.454
1f4gTP4Thymidylate synthase/0.454
1m2qMNXCasein kinase II subunit alpha2.7.11.10.454
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.454
1sj0E4DEstrogen receptor/0.454
2a4zBYMPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
2b1pAIZMitogen-activated protein kinase 102.7.11.240.454
2vgoAD5Aurora kinase B-A2.7.11.10.454
2vn0TDZCytochrome P450 2C8/0.454
2vtrLZBCyclin-dependent kinase 22.7.11.220.454
2x4f16XMyosin light chain kinase family member 42.7.11.10.454
2x7gPVBSRSF protein kinase 22.7.11.10.454
2xvw9NRSerum albumin/0.454
2znnS44Peroxisome proliferator-activated receptor alpha/0.454
3ar7TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.454
3ggfGVDSerine/threonine-protein kinase 26/0.454
3h18PMSEsterase/lipase/0.454
3lctADPALK tyrosine kinase receptor2.7.10.10.454
3otuBI43-phosphoinositide-dependent protein kinase 12.7.11.10.454
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.454
4bcpT3CCyclin-dependent kinase 22.7.11.220.454
4eevL1XHepatocyte growth factor receptor2.7.10.10.454
4ez50RSCyclin-dependent kinase 62.7.11.220.454
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.454
4otpADPSerine/threonine-protein kinase RIO12.7.11.10.454
1f28UMPThymidylate synthase2.1.1.450.453
1ir3ANPInsulin receptor2.7.10.10.453
1tktH12Gag-Pol polyprotein2.7.7.490.453
1v79FR7Adenosine deaminase3.5.4.40.453
2bj4OHTEstrogen receptor/0.453
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.453
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.453
2wedPP6Penicillopepsin-13.4.23.200.453
2x20PIDPeridinin-chlorophyll a-binding protein 1, chloroplastic/0.453
2y6o1N1Ephrin type-A receptor 42.7.10.10.453
3bejMUFBile acid receptor/0.453
3gieACPSensor histidine kinase DesK2.7.13.30.453
3hllI45Mitogen-activated protein kinase 14/0.453
3kjsDQ1Bifunctional dihydrofolate reductase-thymidylate synthase/0.453
3kytHC2Nuclear receptor ROR-gamma/0.453
3w0sANPHygromycin-B 4-O-kinase2.7.1.1630.453
3w16P9JAurora kinase A2.7.11.10.453
3w2sW2REpidermal growth factor receptor2.7.10.10.453
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.453
3zrmZRMGlycogen synthase kinase-3 beta2.7.11.260.453
4bhzZ0BDual specificity protein kinase TTK2.7.12.10.453
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.453
4gk2L66Ephrin type-A receptor 32.7.10.10.453
4j6i1JVPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4l435FIRibosomal protein S6 kinase beta-12.7.11.10.453
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.453
1a27ESTEstradiol 17-beta-dehydrogenase 11.1.1.620.452
1ia1TQ3Dihydrofolate reductase1.5.1.30.452
1iwiCAMCamphor 5-monooxygenase1.14.15.10.452
1j3kWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.452
1m2rMNYCasein kinase II subunit alpha2.7.11.10.452
1nq7ARLNuclear receptor ROR-beta/0.452
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.452
1ppjANYCytochrome b/0.452
1t86CAMCamphor 5-monooxygenase1.14.15.10.452
1y56ATPUncharacterized protein/0.452
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.452
2btrU73Cyclin-dependent kinase 22.7.11.220.452
2iw94SPCyclin-dependent kinase 22.7.11.220.452
2ovmAS0Progesterone receptor/0.452
2qo4CHDFatty acid-binding protein 10-A, liver basic/0.452
2vu3LZECyclin-dependent kinase 22.7.11.220.452
2wotZZGTGF-beta receptor type-12.7.11.300.452
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.452
2ydoADNAdenosine receptor A2a/0.452
2yejXQKHeat shock protein HSP 90-alpha/0.452
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.452
2zdu446Mitogen-activated protein kinase 102.7.11.240.452
3adaNADSubunit alpha of sarocosine oxidase/0.452
3b9lAZZSerum albumin/0.452
3bfb9ODPheromone-binding protein ASP1/0.452
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.452
3icrCOACoenzyme A disulfide reductase/0.452
3megT27Gag-Pol polyprotein2.7.7.490.452
3nr4PYVAbscisic acid receptor PYL2/0.452
3pxkPXKFocal adhesion kinase 12.7.10.20.452
3qzgX67Cyclin-dependent kinase 22.7.11.220.452
3s2pPMUCyclin-dependent kinase 22.7.11.220.452
3unj0BXCyclin-dependent kinase 22.7.11.220.452
3vt5YI2Vitamin D3 receptor/0.452
3vt8YI3Vitamin D3 receptor/0.452
3vvpBNUUncharacterized protein/0.452
4c4f7CEDual specificity protein kinase TTK2.7.12.10.452
4fto3HKSerine/threonine-protein kinase Chk12.7.11.10.452
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
4iui1GQEstrogen receptor/0.452
4o4fATPKinase/0.452
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.452
1d3hA26Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.451
1hpzAAPGag-Pol polyprotein2.7.7.490.451
1j3iWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.451
1unlRRCCyclin-dependent-like kinase 52.7.11.10.451
2bxmIMNSerum albumin/0.451
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.451
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.451
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.451
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.451
2qe4JJ3Estrogen receptor/0.451
2w4jADPDeath-associated protein kinase 12.7.11.10.451
2y7jB49Phosphorylase b kinase gamma catalytic chain, liver/testis isoform2.7.11.190.451
2yn8STUEphrin type-B receptor 42.7.10.10.451
2z2w770Wee1-like protein kinase2.7.10.20.451
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.451
3be9P04Casein kinase II subunit alpha2.7.11.10.451
3emg685Tyrosine-protein kinase SYK2.7.10.20.451
3ez2ADPPlasmid partition protein A/0.451
3glmCOOGlutaconyl-CoA decarboxylase alpha subunit/0.451
3h4vNAPPteridine reductase 11.5.1.330.451
3koo24DBifunctional epoxide hydrolase 23.3.2.100.451
3mpaSB2Mitogen-activated protein kinase 14/0.451
3n8zFLPProstaglandin G/H synthase 11.14.99.10.451
3nxtD2EDihydrofolate reductase1.5.1.30.451
3r374CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.451
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.451
3sw719KCyclin-dependent kinase 22.7.11.220.451
3tkuM77Serine/threonine-protein kinase MRCK beta2.7.11.10.451
3tucFPWTyrosine-protein kinase SYK2.7.10.20.451
3vspEK8Peroxisome proliferator-activated receptor gamma/0.451
4at3LTIBDNF/NT-3 growth factors receptor2.7.10.10.451
4c4g7RODual specificity protein kinase TTK2.7.12.10.451
4jv618FRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.451
4kd79DRDihydrofolate reductase1.5.1.30.451
4nfn2KCTau-tubulin kinase 12.7.11.10.451
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.451
5k2aZMAAdenosine receptor A2a/0.451
1e7qNAPGDP-L-fucose synthase/0.450
1wvySTUDeath-associated protein kinase 12.7.11.10.450
2fziDH3Dihydrofolate reductase1.5.1.30.450
2q6sPLBPeroxisome proliferator-activated receptor gamma/0.450
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.450
2xa4AZ5Tyrosine-protein kinase JAK2/0.450
2xvv9DNSerum albumin/0.450
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.450
3dmjGWEPol protein/0.450
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.450
3gphOIDCytochrome P450 2E11.14.130.450
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
3kljFADNADH-rubredoxin oxidoreductase1.18.1.10.450
3l8p0CEAngiopoietin-1 receptor2.7.10.10.450
3lltANPProtein serine/threonine kinase-1/0.450
3qtxX43Cyclin-dependent kinase 22.7.11.220.450
3r34COA4-hydroxybenzoyl-CoA thioesterase3.1.2.230.450
3s1dZIRCytokinin dehydrogenase 11.5.99.120.450
3sp9IL2Peroxisome proliferator-activated receptor delta/0.450
3v3vMYUMitogen-activated protein kinase 82.7.11.240.450
3vf80JETyrosine-protein kinase SYK2.7.10.20.450
3vid4TTVascular endothelial growth factor receptor 22.7.10.10.450
3vs0VS0Tyrosine-protein kinase HCK2.7.10.20.450
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4ap1NAPSteroid monooxygenase/0.450
4b7sQLECytochrome P450 monooxygenase PikC/0.450
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.450
4fnyI3KALK tyrosine kinase receptor2.7.10.10.450
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.450
4h4xFADBiphenyl dioxygenase ferredoxin reductase subunit/0.450
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.450
4kbc1QJCasein kinase I isoform delta2.7.11.10.450
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.450
5aaaVGHALK tyrosine kinase receptor2.7.10.10.450
5aabVGHALK tyrosine kinase receptor2.7.10.10.450
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.450
5dosATPAurora kinase A2.7.11.10.450
1ad5ANPTyrosine-protein kinase HCK2.7.10.20.449
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.449
1m78CLZDihydrofolate reductase1.5.1.30.449
1owmFADDeoxyribodipyrimidine photo-lyase4.1.99.30.449
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.449
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.449
1rx8FOLDihydrofolate reductase1.5.1.30.449
1v35NAIEnoyl-ACP reductase/0.449
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.449
2bkzSBCCyclin-dependent kinase 22.7.11.220.449
2btsU32Cyclin-dependent kinase 22.7.11.220.449
2dwbANPAurora kinase A2.7.11.10.449
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
2wueKEK4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.449
3eljGS7Mitogen-activated protein kinase 82.7.11.240.449
3iggEFQCyclin-dependent kinase 22.7.11.220.449
3is9AC7Gag-Pol polyprotein2.7.7.490.449
3lijANPCalcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands/0.449
3owj1ELCasein kinase II subunit alpha2.7.11.10.449
3pvwQRXBeta-adrenergic receptor kinase 12.7.11.150.449
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.449
3qruX19Cyclin-dependent kinase 22.7.11.220.449
3vf2ADPnebramycin 5' synthase6.1.2.20.449
3vtdTKDVitamin D3 receptor/0.449
4c57FEFCyclin-G-associated kinase2.7.11.10.449
4dquNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
4fsyHK7Serine/threonine-protein kinase Chk12.7.11.10.449
4fz70VHTyrosine-protein kinase SYK2.7.10.20.449
4jbqVX6Aurora kinase A2.7.11.10.449
4oj4DIFPeroxisome proliferator-activated receptor gamma/0.449
4ylhYE1(3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase/0.449
5dr9SKEAurora kinase A2.7.11.10.449
1dayGNPCasein kinase II subunit alpha2.7.11.10.448
1dz4CAMCamphor 5-monooxygenase1.14.15.10.448
1hk5T44Serum albumin/0.448
1hnvTBOGag-Pol polyprotein2.7.7.490.448
1ndzFR5Adenosine deaminase3.5.4.40.448
1oirHDYCyclin-dependent kinase 22.7.11.220.448
1p4fDRGDeath-associated protein kinase 12.7.11.10.448
1t87CAMCamphor 5-monooxygenase1.14.15.10.448
1tvrTB9Gag-Pol polyprotein2.7.7.490.448
2balPQAMitogen-activated protein kinase 14/0.448
2j0m4STFocal adhesion kinase 12.7.10.20.448
2jn3JN3Fatty acid-binding protein, liver/0.448
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.448
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.448
3amyAGICasein kinase II subunit alpha2.7.11.10.448
3cseN22Uncharacterized protein/0.448
3d7tSTUTyrosine-protein kinase CSK/0.448
3ekx1UNGag-Pol polyprotein3.4.23.160.448
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.448
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.448
3hz142CHeat shock protein HSP 90-alpha/0.448
3jsuKA5Bifunctional dihydrofolate reductase-thymidylate synthase/0.448
3mvhWFERAC-alpha serine/threonine-protein kinase2.7.11.10.448
3qj5022Alcohol dehydrogenase class-31.1.1.10.448
3r1sX73Cyclin-dependent kinase 22.7.11.220.448
3sqq99ZCyclin-dependent kinase 22.7.11.220.448
3um5CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.448
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.448
3vquO22Dual specificity protein kinase TTK2.7.12.10.448
4a86H35Major pollen allergen Bet v 1-A/0.448
4bddZ0OSerine/threonine-protein kinase Chk22.7.11.10.448
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.448
4d4sBI9Focal adhesion kinase 12.7.10.20.448
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.448
4egnTWOCytochrome P450/0.448
4enhFVXCholesterol 24-hydroxylase/0.448
4fv4EK7Mitogen-activated protein kinase 12.7.11.240.448
4hys1BJMitogen-activated protein kinase 82.7.11.240.448
4i2pG73Gag-Pol polyprotein2.7.7.490.448
4i3wNADAldehyde dehydrogenase (NAD+)/0.448
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.448
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.448
4kwi1TJReductase homolog/0.448
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.448
4uyaAGSMitogen-activated protein kinase kinase kinase 212.7.11.250.448
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.448
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.448
5d7pAR6NAD-dependent protein deacetylase sirtuin-23.5.10.448
1ia4TQ6Dihydrofolate reductase1.5.1.30.447
1oecAA2Fibroblast growth factor receptor 2/0.447
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.447
1vjy460TGF-beta receptor type-12.7.11.300.447
2blcCP7Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.447
2fvdLIACyclin-dependent kinase 22.7.11.220.447
2hw2RFPRifampin ADP-ribosyl transferase/0.447
2j7t274Serine/threonine-protein kinase 102.7.11.10.447
2w3vTOPDihydrofolate reductase/0.447
2xp2VGHALK tyrosine kinase receptor2.7.10.10.447
2y9qANPMitogen-activated protein kinase 12.7.11.240.447
2yboSAHMethyltransferase/0.447
2yejZZ3Heat shock protein HSP 90-alpha/0.447
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.447
2zdt46CMitogen-activated protein kinase 102.7.11.240.447
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.447
3cd2MTXDihydrofolate reductase1.5.1.30.447
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.447
3cz09ODPheromone-binding protein ASP1/0.447
3dpd41APhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
3i0rRT3Gag-Pol polyprotein2.7.7.490.447
3icsCOACoenzyme A disulfide reductase/0.447
3ictADPCoenzyme A disulfide reductase/0.447
3ielU5PRibonuclease TTHA02523.10.447
3mfuANPPeripheral plasma membrane protein CASK2.7.11.10.447
3pp1IZGDual specificity mitogen-activated protein kinase kinase 12.7.12.20.447
3rps4B0Casein kinase II subunit alpha2.7.11.10.447
3srrQ20Dihydrofolate reductase1.5.1.30.447
3sruQ26Dihydrofolate reductase1.5.1.30.447
4aoi4K0Hepatocyte growth factor receptor2.7.10.10.447
4bcmT7ZCyclin-dependent kinase 22.7.11.220.447
4cnkFADL-amino acid oxidase/0.447
4cp4CAMCamphor 5-monooxygenase1.14.15.10.447
4f630S7Fibroblast growth factor receptor 1/0.447
4fx360KCyclin-dependent kinase 22.7.11.220.447
4ifvT27Gag-Pol polyprotein2.7.7.490.447
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.447
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.447
4k4j1O8Retinoic acid receptor RXR-alpha/0.447
4l4aCAMCamphor 5-monooxygenase1.14.15.10.447
4lvg20ONicotinamide phosphoribosyltransferase2.4.2.120.447
4o4eATPKinase/0.447
4okt198Androgen receptor/0.447
4qpmADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.447
3reyXACAdenosine receptor A2a/0.447
1cd2FOLDihydrofolate reductase1.5.1.30.446
1kb9SMACytochrome b/0.446
1zeoC01Peroxisome proliferator-activated receptor gamma/0.446
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.446
2cdaNAPGlucose 1-dehydrogenase/0.446
2fxdDR7Pol polyprotein/0.446
2hwrDRDPeroxisome proliferator-activated receptor gamma/0.446
2ie0ZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.446
2p7zOHTEstrogen-related receptor gamma/0.446
2po7CHDFerrochelatase, mitochondrial4.99.1.10.446
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.446
2w05FRTCyclin-dependent kinase 22.7.11.220.446
2x9fX9FEphrin type-B receptor 42.7.10.10.446
3a7jADPSerine/threonine-protein kinase 242.7.11.10.446
3ar4TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.446
3gd3FADApoptosis-inducing factor 1, mitochondrial1.1.10.446
3gu5ANPDeath-associated protein kinase 12.7.11.10.446
3okxSAMS-adenosyl-L-methionine-binding protein RPA0152/0.446
3qyw6PBMitogen-activated protein kinase 12.7.11.240.446
3ttjJBIMitogen-activated protein kinase 102.7.11.240.446
3um81CYBifunctional dihydrofolate reductase-thymidylate synthase/0.446
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.446
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.446
4ap7F47Hepatocyte growth factor receptor2.7.10.10.446
4bwaN0BPyrrolysine--tRNA ligase/0.446
4dtaADNAPH(2'')-Id/0.446
4ek1CAMCamphor 5-monooxygenase1.14.15.10.446
4eos1ROCyclin-dependent kinase 22.7.11.220.446
4ho3TTPGlucose-1-phosphate thymidylyltransferase/0.446
4j6cSTRCytochrome P450 monooxygenase/0.446
4kfj1R0Dihydrofolate reductase1.5.1.30.446
4mvfSTUCalcium-dependent protein kinase 22.7.11.10.446
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.446
4rrqA3SThreonine--tRNA ligase6.1.1.30.446
4xwtU5PRibonuclease J/0.446
5uviZMAAdenosine receptor A2a/0.446
1ckpPVBCyclin-dependent kinase 22.7.11.220.445
1csnATPCasein kinase I homolog 12.7.11.10.445
1dyrTOPDihydrofolate reductase1.5.1.30.445
1ndeMONEstrogen receptor beta/0.445
1ownFADDeoxyribodipyrimidine photo-lyase4.1.99.30.445
1wrlTFPTroponin C, slow skeletal and cardiac muscles/0.445
1zyjBI5Mitogen-activated protein kinase 14/0.445
2h96893Mitogen-activated protein kinase 82.7.11.240.445
2itnANPEpidermal growth factor receptor2.7.10.10.445
2jkkBI9Focal adhesion kinase 12.7.10.20.445
2om9AJAPeroxisome proliferator-activated receptor gamma/0.445
2pmoHMDProtein kinase 7/0.445
2prh238Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.445
2pvhP19Casein kinase II subunit alpha2.7.11.10.445
2pwlACPFibroblast growth factor receptor 2/0.445
2q59240Peroxisome proliferator-activated receptor gamma/0.445
2r3lSCWCyclin-dependent kinase 22.7.11.220.445
2r5tANPSerine/threonine-protein kinase Sgk12.7.11.10.445
2uzeC95Cyclin-dependent kinase 22.7.11.220.445
2wmrZYRSerine/threonine-protein kinase Chk12.7.11.10.445
2wouZZFTGF-beta receptor type-12.7.11.300.445
2y46MIVMycinamicin IV hydroxylase/epoxidase/0.445
2yfxVGHALK tyrosine kinase receptor2.7.10.10.445
3b2tM33Fibroblast growth factor receptor 2/0.445
3jw3TOPDihydrofolate reductase/0.445
3kgaLX9MAP kinase-activated protein kinase 22.7.11.10.445
3lfqA28Cyclin-dependent kinase 22.7.11.220.445
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.445
3qm4PN0Cytochrome P450 2D6/0.445
3qqgX06Cyclin-dependent kinase 22.7.11.220.445
3r9dX6BCyclin-dependent kinase 22.7.11.220.445
3tk3CPZCytochrome P450 2B41.14.14.10.445
3tnwF18Cyclin-dependent kinase 22.7.11.220.445
3w2o03PEpidermal growth factor receptor2.7.10.10.445
4a2jAS0Progesterone receptor/0.445
4bdeCWSSerine/threonine-protein kinase Chk22.7.11.10.445
4cfnJYMCyclin-dependent kinase 22.7.11.220.445
4ek816KCyclin-dependent kinase 22.7.11.220.445
4fks46KCyclin-dependent kinase 22.7.11.220.445
4fkw62KCyclin-dependent kinase 22.7.11.220.445
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.445
4jia1K3Tyrosine-protein kinase JAK2/0.445
4jvmXDIEstrogen sulfotransferase2.8.2.40.445
4nmbFADBifunctional protein PutA/0.445
4o701QKBromodomain-containing protein 4/0.445
4oaeCLMUncharacterized protein/0.445
4ok1198Androgen receptor/0.445
4ysjADPCalmodulin-like domain protein kinase/0.445
5aacVGHALK tyrosine kinase receptor2.7.10.10.445
5av047XDeath-associated protein kinase 12.7.11.10.445
1ezvSMACytochrome b/0.444
1g4sTPSThiamine-phosphate synthase/0.444
1r6g442Thyroid hormone receptor beta/0.444
1r9oFLPCytochrome P450 2C9/0.444
1rd4L08Integrin alpha-L/0.444
1s6qTPBGag-Pol polyprotein2.7.7.490.444
1sn0T44Transthyretin/0.444
1tkzH16Gag-Pol polyprotein2.7.7.490.444
1y6bAAXVascular endothelial growth factor receptor 22.7.10.10.444
2b5j3ACGag-Pol polyprotein2.7.7.490.444
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.444
2fzkCTPAspartate carbamoyltransferase regulatory chain/0.444
2i4tUA2Purine nucleoside phosphorylase, putative/0.444
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.444
2ijmATPFocal adhesion kinase 12.7.10.20.444
2qo9ANPEphrin type-A receptor 32.7.10.10.444
2w1gL0GAurora kinase A2.7.11.10.444
2w3aTOPDihydrofolate reductase1.5.1.30.444
2xngA0HAurora kinase A2.7.11.10.444
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.444
3d7kD7KBenzaldehyde lyase/0.444
3ddw055Glycogen phosphorylase, liver form2.4.1.10.444
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.444
3e5aVX6Aurora kinase A2.7.11.10.444
3gobHXXDdmC/0.444
3inwJZBHeat shock protein HSP 90-alpha/0.444
3new3NEMitogen-activated protein kinase 14/0.444
3oibFDAPutative acyl-CoA dehydrogenase/0.444
3orkAGSSerine/threonine protein kinase/0.444
3qqkX02Cyclin-dependent kinase 22.7.11.220.444
3rk708ZCyclin-dependent kinase 22.7.11.220.444
3uk6ADPRuvB-like 23.6.4.120.444
3uxe465Ribosyldihydronicotinamide dehydrogenase [quinone]/0.444
3zewSTUEphrin type-B receptor 42.7.10.10.444
3zvvXAZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4anqVGHALK tyrosine kinase receptor2.7.10.10.444
4b2wBZ0Glucose-1-phosphate thymidylyltransferase/0.444
4c35NU3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
4e0u0MVCyclic dipeptide N-prenyltransferase/0.444
4ez30S0Cyclin-dependent kinase 22.7.11.220.444
4fl1ANPTyrosine-protein kinase SYK2.7.10.20.444
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.444
4kba1QMCasein kinase I isoform delta2.7.11.10.444
4ryvZEAProtein LlR18A/0.444
4xivACPChemotaxis protein CheA2.7.13.30.444
5ap57RODual specificity protein kinase TTK2.7.12.10.444
5kghACOPredicted acetyltransferase/0.444
1bl6SB6Mitogen-activated protein kinase 14/0.443
1fvt106Cyclin-dependent kinase 22.7.11.220.443
1gih1PUCyclin-dependent kinase 22.7.11.220.443
1h1pCMGCyclin-dependent kinase 22.7.11.220.443
1icqOPD12-oxophytodienoate reductase 11.3.1.420.443
1iidNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.443
1ikvEFZGag-Pol polyprotein2.7.7.490.443
1lrhNLAAuxin-binding protein 1/0.443
1pxmCK5Cyclin-dependent kinase 22.7.11.220.443
1y4lSVRBasic phospholipase A2 homolog 2/0.443
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.443
2cig1DGDihydrofolate reductase1.5.1.30.443
2excJNKMitogen-activated protein kinase 102.7.11.240.443
2fpcSCGStrictosidine synthase4.3.3.20.443
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.443
2iebZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
2rqfJH3Hemolymph juvenile hormone binding protein/0.443
2vg7NNIGag-Pol polyprotein2.7.7.490.443
2vr1ATFBiotin carboxylase6.3.4.140.443
2wi72KLHeat shock protein HSP 90-alpha/0.443
2xvdAS6Ephrin type-B receptor 42.7.10.10.443
2y4lGDPUncharacterized protein/0.443
2y98MIVMycinamicin IV hydroxylase/epoxidase/0.443
2zbaZBATrichothecene 3-O-acetyltransferase/0.443
3ar6TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.443
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.443
3cxhSMACytochrome b/0.443
3d78NBBPheromone-binding protein ASP1/0.443
3eel53TUncharacterized protein/0.443
3g5mFADRibosyldihydronicotinamide dehydrogenase [quinone]/0.443
3iro2CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.443
3l0lHC3Nuclear receptor ROR-gamma/0.443
3qlhT27Gag-Pol polyprotein2.7.7.490.443
3r71X86Cyclin-dependent kinase 22.7.11.220.443
3w2rW2REpidermal growth factor receptor2.7.10.10.443
3w32W32Epidermal growth factor receptor2.7.10.10.443
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.443
4c3rACPAurora kinase A2.7.11.10.443
4eok4SPCyclin-dependent kinase 22.7.11.220.443
4fkt48KCyclin-dependent kinase 22.7.11.220.443
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.443
4hgs15GCasein kinase I isoform gamma-32.7.11.10.443
4kkyCAMCamphor 5-monooxygenase1.14.15.10.443
4pkhADPActin, alpha skeletal muscle/0.443
4qo9627Serine/threonine-protein kinase 242.7.11.10.443
1ay0TPPTransketolase 12.2.1.10.442
1diuBDMDihydrofolate reductase1.5.1.30.442
1urwI1PCyclin-dependent kinase 22.7.11.220.442
1vj3TABDihydrofolate reductase1.5.1.30.442
1xl2189Gag-Pol polyprotein3.4.23.160.442
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.442
1yolS03Proto-oncogene tyrosine-protein kinase Src2.7.10.20.442
2aclREARetinoic acid receptor RXR-alpha/0.442
2b0m201Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.442
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.442
2oyfIACBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.442
2pujHPZ2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase3.7.1.80.442
2qkrIXMCdc2-like CDK2/CDC28 like protein kinase/0.442
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.442
3dfcANPDeath-associated protein kinase 12.7.11.10.442
3frdDHFDihydrofolate reductase1.5.1.30.442
3h0sB38Acetyl-CoA carboxylase/0.442
3hz137DHeat shock protein HSP 90-alpha/0.442
3ia4MTXDihydrofolate reductase/0.442
3jwm5WBDihydrofolate reductase/0.442
3lakKR1Gag-Pol polyprotein2.7.7.490.442
3pe6ZYHMonoglyceride lipase/0.442
3r7yZ04Cyclin-dependent kinase 22.7.11.220.442
3rk909ZCyclin-dependent kinase 22.7.11.220.442
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.442
3vjhJ35Peroxisome proliferator-activated receptor gamma/0.442
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.442
3wmxNADNAD dependent epimerase/dehydratase/0.442
3zc5W9ZHepatocyte growth factor receptor2.7.10.10.442
3zonIK1Non-receptor tyrosine-protein kinase TYK22.7.10.20.442
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4bdbODOSerine/threonine-protein kinase Chk22.7.11.10.442
4cdmFO1Deoxyribodipyrimidine photolyase/0.442
4fkg4CKCyclin-dependent kinase 22.7.11.220.442
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.442
4ie6UN9Alpha-ketoglutarate-dependent dioxygenase FTO/0.442
4iwd1JCHepatocyte growth factor receptor2.7.10.10.442
4klrCHDFerrochelatase, mitochondrial4.99.1.10.442
4lfiGNPCasein kinase II subunit alpha2.7.11.10.442
4mxyDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.442
4mxzDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.442
4nka2K7Fibroblast growth factor receptor 1/0.442
4oavACP2-5A-dependent ribonuclease3.1.260.442
4xlvACPInsulin receptor2.7.10.10.442
5cp4CAMCamphor 5-monooxygenase1.14.15.10.442
5kgpACOPredicted acetyltransferase/0.442
5k2bZMAAdenosine receptor A2a/0.442
1gii1PUCyclin-dependent kinase 22.7.11.220.441
1iyzNDPProbable quinone oxidoreductase/0.441
1jomFFODihydrofolate reductase1.5.1.30.441
1likADNAdenosine kinase2.7.1.200.441
1pjkANPCasein kinase II subunit alpha2.7.11.10.441
1pmn984Mitogen-activated protein kinase 102.7.11.240.441
1py5PY1TGF-beta receptor type-12.7.11.300.441
1r2jFADFkbI/0.441
1t88CAMCamphor 5-monooxygenase1.14.15.10.441
1yinCM3Estrogen receptor/0.441
1zhzERGOxysterol-binding protein homolog 4/0.441
2gtk208Peroxisome proliferator-activated receptor gamma/0.441
2hmaSAMtRNA-specific 2-thiouridylase MnmA/0.441
2jfgUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.441
2ovhAS0Progesterone receptor/0.441
2pvlP55Casein kinase II subunit alpha2.7.11.10.441
2q8sL92Peroxisome proliferator-activated receptor gamma/0.441
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.441
2z7lS91Mitogen-activated protein kinase 12.7.11.240.441
3ag9A02cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
3cgoJNOMitogen-activated protein kinase 102.7.11.240.441
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.441
3em6017Gag-Pol polyprotein3.4.23.160.441
3f82353Hepatocyte growth factor receptor2.7.10.10.441
3nc9TR3Ketohexokinase/0.441
3nux3NVCyclin-dependent kinase 62.7.11.220.441
3nwxKVSGag-Pol polyprotein3.4.23.160.441
3oeyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
3p3e3P3UDP-3-O-acyl-N-acetylglucosamine deacetylase/0.441
3qfvNM7Serine/threonine-protein kinase MRCK beta2.7.11.10.441
3qly55VUncharacterized protein/0.441
3qx4X4BCyclin-dependent kinase 22.7.11.220.441
3r3c4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.441
3s1cZIRCytokinin dehydrogenase 11.5.99.120.441
3s79ASDAromatase1.14.14.140.441
3t2zFADSulfide-quinone reductase/0.441
3uli1N3Cyclin-dependent kinase 22.7.11.220.441
3zdu38RCyclin-dependent kinase-like 32.7.11.220.441
3zk5Z18Cytochrome P450 monooxygenase PikC/0.441
4a4wYFBPeroxisome proliferator-activated receptor gamma/0.441
4b99R4LMitogen-activated protein kinase 72.7.11.240.441
4cd0AWJALK tyrosine kinase receptor2.7.10.10.441
4fkpLS5Cyclin-dependent kinase 22.7.11.220.441
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.441
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.441
4ia7BIVVitamin D3 receptor A/0.441
4l4bCAMCamphor 5-monooxygenase1.14.15.10.441
4r20AERCytochrome P450 family 17 polypeptide 2/0.441
4ri1ACOUDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase2.3.1.2020.441
4ykgNADAlkyl hydroperoxide reductase subunit F1.8.10.441
5cp8TCUEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
5d7pOCZNAD-dependent protein deacetylase sirtuin-23.5.10.441
5k2dZMAAdenosine receptor A2a/0.441
1ai9NDPDihydrofolate reductase1.5.1.30.440
1dajMOTDihydrofolate reductase1.5.1.30.440
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
1f4fTP3Thymidylate synthase/0.440
1fm69CRRetinoic acid receptor RXR-alpha/0.440
1g3mPCQEstrogen sulfotransferase2.8.2.40.440
1jipKTN6-deoxyerythronolide B hydroxylase/0.440
1jscFADAcetolactate synthase catalytic subunit, mitochondrial2.2.1.60.440
1knuYPAPeroxisome proliferator-activated receptor gamma/0.440
1q4xG24Thyroid hormone receptor beta/0.440
1zx1CB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.440
2ay3MPPAromatic-amino-acid aminotransferase2.6.1.570.440
2c5nCK8Cyclin-dependent kinase 22.7.11.220.440
2f2cAP9Cyclin-dependent kinase 62.7.11.220.440
2harOCCVitamin D3 receptor/0.440
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.440
2p1u4TNRetinoic acid receptor RXR-alpha/0.440
2pmlANPUncharacterized protein/0.440
2pvnP63Casein kinase II subunit alpha2.7.11.10.440
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.440
2qjpANJCytochrome b/0.440
2w3wVG9Dihydrofolate reductase/0.440
2wecPP5Penicillopepsin-13.4.23.200.440
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.440
2zb45OPProstaglandin reductase 21.3.1.480.440
3ctj320Hepatocyte growth factor receptor2.7.10.10.440
3d0bSNXHeat shock protein HSP 90-alpha/0.440
3f5p741Insulin-like growth factor 1 receptor2.7.10.10.440
3ldgSAHUncharacterized protein/0.440
3lu6IMXSerum albumin/0.440
3meeT27Gag-Pol polyprotein2.7.7.490.440
3negPYVAbscisic acid receptor PYL1/0.440
3ox34X4Ribosyldihydronicotinamide dehydrogenase [quinone]/0.440
3r6pA8SAbscisic acid receptor PYL10/0.440
3unk0BYCyclin-dependent kinase 22.7.11.220.440
3zxzKRWHepatocyte growth factor receptor2.7.10.10.440
4a51DQ8Kinesin-like protein KIF11/0.440
4an35Y0Dual specificity mitogen-activated protein kinase kinase 12.7.12.20.440
4eoi1ROCyclin-dependent kinase 22.7.11.220.440
4f640S8Fibroblast growth factor receptor 1/0.440
4f700STCyclin-dependent kinase 82.7.11.220.440
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.440
4g73FADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.440
4gk4L90Ephrin type-A receptor 32.7.10.10.440
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.440
4l9kEHFSerum albumin/0.440
4o0uADNAurora kinase A2.7.11.10.440
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.440
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.440
5bp9SAHPutative methyltransferase protein/0.440
5fbhTCRExtracellular calcium-sensing receptor/0.440
2ycxP32Beta-1 adrenergic receptor/0.440