sc-PDB

List of CHEMBLId :

This value allows a number of roughly comparable measures of half-maximal response concentration/potency/affinity to be compared on a negative logarithmic scale (e.g., an IC50 measurement of 1nM would have a pChEMBL value of 9).

Uniprot Annotation

Name:	Focal adhesion kinase 1
ID:	FAK1_CHICK
AC:	Q00944
Organism:	Gallus gallus
Reign:	Eukaryota
TaxID:	9031
EC Number:	2.7.10.2

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Chains:

Chain Name:	Percentage of Residues within binding site
A	100 %

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Ligand binding site composition:

B-Factor:	32.365
Number of residues:	33
Including
Standard Amino Acids:	33
Non Standard Amino Acids:	0
Water Molecules:	0
Cofactors:
Metals:

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Cavity properties

Ligandability	Volume (Å3)
1.091	475.875

% Hydrophobic	% Polar
52.48	47.52
According to VolSite

HET Code:	VG8
Formula:	C30H37ClN7O2
Molecular weight:	563.113 g/mol
DrugBank ID:	-
Buried Surface Area:	55.11 %
Polar Surface area:	87.06 Å2

Number of
H-Bond Acceptors:	7
H-Bond Donors:	3
Rings:	6
Aromatic rings:	3
Anionic atoms:	0
Cationic atoms:	1
Rule of Five Violation:	1
Rotatable Bonds:	7

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Mass center Coordinates

X	Y	Z
10.3929	1.01395	26.6241

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