Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1h74 | AGS | Homoserine kinase | 2.7.1.39 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1h74 | AGS | Homoserine kinase | 2.7.1.39 | 1.000 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.572 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.560 | |
| 1h72 | ANP | Homoserine kinase | 2.7.1.39 | 0.523 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.510 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.509 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.499 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.499 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.499 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.498 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.498 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.498 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.496 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.495 | |
| 3zuy | TCH | Transporter | / | 0.493 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.492 | |
| 2hma | SAM | tRNA-specific 2-thiouridylase MnmA | / | 0.492 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.491 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.490 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.490 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.489 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.489 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.489 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.488 | |
| 4awp | 99A | Heat shock protein HSP 90-alpha | / | 0.488 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.488 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.488 | |
| 3gob | HXX | DdmC | / | 0.486 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.486 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.485 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.485 | |
| 2ohv | NHL | Glutamate racemase | / | 0.485 | |
| 3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.485 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.484 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.483 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.483 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.482 | |
| 4ceq | QCH | Integrase | / | 0.482 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.481 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.481 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.481 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.481 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.481 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.480 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.479 | |
| 3tz3 | B36 | Acetyl-CoA carboxylase | / | 0.479 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.479 | |
| 5itz | LOC | Tubulin beta-2B chain | / | 0.479 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.478 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.478 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.478 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.478 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.478 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.478 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.478 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.478 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.477 | |
| 3cgc | COA | Coenzyme A disulfide reductase | / | 0.477 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.477 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.476 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.476 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.476 | |
| 4hnc | 0UT | Mandelate racemase | / | 0.476 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.475 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.475 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.475 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.475 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.475 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.475 | |
| 3k2h | LYA | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.475 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.475 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.475 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.475 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.474 | |
| 1m75 | CAA | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.474 | |
| 2ii6 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.474 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.474 | |
| 5bsg | NAP | Pyrroline-5-carboxylate reductase | / | 0.474 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.473 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.473 | |
| 2y8q | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.473 | |
| 3kxw | 1ZZ | Saframycin Mx1 synthetase B | / | 0.473 | |
| 3mkn | DNB | Pyrimidine-specific ribonucleoside hydrolase RihB | / | 0.473 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.472 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.472 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.472 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.472 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.472 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.472 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.472 | |
| 3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.472 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.472 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.472 | |
| 1a59 | COA | 2-methylcitrate synthase | / | 0.471 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.471 | |
| 1boo | SAH | Modification methylase PvuII | 2.1.1.113 | 0.471 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.471 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.471 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.471 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 3wv7 | ADP | Hmd co-occurring protein HcgE | / | 0.471 | |
| 4nxu | ADP | Mitochondrial dynamics protein MID51 | / | 0.471 | |
| 5a3b | APR | SIR2 family protein | / | 0.471 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.470 | |
| 1zgy | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.470 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.470 | |
| 2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.470 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.470 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.470 | |
| 1fcb | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.469 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.469 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.469 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.469 | |
| 3tvu | B37 | Acetyl-CoA carboxylase | / | 0.469 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.469 | |
| 4dx7 | DM2 | Multidrug efflux pump subunit AcrB | / | 0.469 | |
| 4lrz | ADP | PEP-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL | 2.7 | 0.469 | |
| 5cyo | GDP | Septin-9 | / | 0.469 | |
| 1i5c | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.468 | |
| 1k8y | 13P | Tryptophan synthase alpha chain | / | 0.468 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.468 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.468 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.468 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.468 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.468 | |
| 1fm6 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.467 | |
| 1i9m | INW | Carbonic anhydrase 2 | 4.2.1.1 | 0.467 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.467 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.467 | |
| 2v9j | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.467 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.467 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.467 | |
| 3wyc | NAP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.467 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.467 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.467 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.467 | |
| 1b8u | NAD | Malate dehydrogenase | / | 0.466 | |
| 1dyh | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.466 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.466 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.466 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.466 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.466 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.466 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.466 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.466 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.466 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 4loi | 1YC | Stimulator of interferon genes protein | / | 0.466 | |
| 1ep1 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.465 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.465 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.465 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.465 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.465 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.465 | |
| 3bc3 | OPT | Cathepsin L1 | 3.4.22.15 | 0.465 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.465 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.465 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.465 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.465 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 4h6k | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.465 | |
| 4k9o | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.465 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.464 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.464 | |
| 1ra3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 3ete | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.464 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.464 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.464 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.463 | |
| 1nqo | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.463 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.463 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.463 | |
| 2iea | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.463 | |
| 3cz7 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.463 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.463 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.463 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.463 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.463 | |
| 4ebf | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.463 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.463 | |
| 4xcv | NDP | Probable hydroxyacid dehydrogenase protein | / | 0.463 | |
| 4yry | FAD | Glutamate synthase, beta subunit | / | 0.463 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 1f0y | CAA | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.462 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.462 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.462 | |
| 2b4r | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.462 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.462 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.462 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.462 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.462 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.462 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.462 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.462 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.462 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.462 | |
| 5il2 | SAH | N6-adenosine-methyltransferase 70 kDa subunit | / | 0.462 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.461 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.461 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.461 | |
| 2aa0 | MTP | Adenosine kinase | 2.7.1.20 | 0.461 | |
| 3b2e | ADP | ATPase GET3 | / | 0.461 | |
| 3gvi | ADP | Malate dehydrogenase | / | 0.461 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.461 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 3vjo | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.461 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 4nvk | 2NY | Peroxidase | / | 0.461 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.461 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.460 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 1j0x | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.460 | |
| 1jkx | 138 | Phosphoribosylglycinamide formyltransferase | / | 0.460 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.460 | |
| 2gs7 | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.460 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.460 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 3a3g | DLZ | Lumazine protein | / | 0.460 | |
| 3cis | ATP | Universal stress protein Rv2623 | / | 0.460 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.460 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.460 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.460 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.460 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.460 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.459 | |
| 1guf | NDP | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.459 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.459 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.459 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.459 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.459 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.459 | |
| 4i02 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.459 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.459 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.458 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.458 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.458 | |
| 1njf | AGS | DNA polymerase III subunit tau | 2.7.7.7 | 0.458 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.458 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 2vou | FAD | 2,6-dihydroxypyridine 3-monooxygenase | 1.14.13.10 | 0.458 | |
| 2vrb | NAP | Triphenylmethane reductase | / | 0.458 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.458 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 3tnl | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.458 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.458 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 4g6g | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.458 | |
| 4l8u | 9AZ | Serum albumin | / | 0.458 | |
| 4qi9 | MTX | Dihydrofolate reductase | / | 0.458 | |
| 1d7l | RFL | p-hydroxybenzoate hydroxylase | / | 0.457 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1qr6 | NAD | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.457 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.457 | |
| 2dgn | DOI | Adenylosuccinate synthetase isozyme 1 | / | 0.457 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.457 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 3jyq | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.457 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.457 | |
| 3pw8 | ACO | 1,2-phenylacetyl-CoA epoxidase, subunit A | 1.14.13.149 | 0.457 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.457 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.457 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.457 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.457 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.457 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.457 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.457 | |
| 1a5b | IGP | Tryptophan synthase alpha chain | / | 0.456 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.456 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.456 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.456 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.456 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.456 | |
| 2g2z | COZ | Malonyl CoA-acyl carrier protein transacylase | 2.3.1.39 | 0.456 | |
| 2itw | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.456 | |
| 2wuf | KEM | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.456 | |
| 2y8l | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.456 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 3cgb | COA | Coenzyme A disulfide reductase | / | 0.456 | |
| 3cge | COA | Coenzyme A disulfide reductase | / | 0.456 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.456 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.456 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.456 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.456 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.456 | |
| 4dpw | AGS | Mevalonate diphosphate decarboxylase | / | 0.456 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.456 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.456 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.456 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.456 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.456 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.455 | |
| 1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.455 | |
| 1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.455 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.455 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.455 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.455 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3duf | R1T | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.455 | |
| 3duf | R1T | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.455 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.455 | |
| 3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.455 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.455 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.455 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.455 | |
| 4gdc | NDP | UDP-galactopyranose mutase | / | 0.455 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.455 | |
| 4l4x | NDP | AmphI | / | 0.455 | |
| 5cwa | 0GA | Anthranilate synthase component 1 | 4.1.3.27 | 0.455 | |
| 5fwn | NAP | Putative dehydrogenase | / | 0.455 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1dyi | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.454 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.454 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.454 | |
| 1xdp | ATP | Polyphosphate kinase | / | 0.454 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.454 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.454 | |
| 2nmt | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.454 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.454 | |
| 3bgx | TMP | Thymidylate synthase | / | 0.454 | |
| 3cop | ADP | Glycogen synthase | 2.4.1.21 | 0.454 | |
| 3ez2 | ADP | Plasmid partition protein A | / | 0.454 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.454 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 3q71 | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.454 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.454 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.454 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.454 | |
| 3vwd | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.454 | |
| 4xxv | NAD | 3-isopropylmalate dehydrogenase | / | 0.454 | |
| 6gsu | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.454 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.453 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.453 | |
| 1zdw | FLV | Prenyltransferase | / | 0.453 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 2e9d | B76 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.453 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.453 | |
| 2itn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.453 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.453 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.453 | |
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 | / | 0.453 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.453 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.453 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.453 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 3t1t | GDP | Probable gliding protein mglA | / | 0.453 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.453 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.453 | |
| 4kz0 | 1UJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 4nxx | GDP | Mitochondrial dynamics protein MID51 | / | 0.453 | |
| 4o0r | X4Z | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.453 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.453 | |
| 5ez7 | FAD | Probable FAD-dependent oxidoreductase PA4991 | / | 0.453 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.452 | |
| 1nlm | UD1 | UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase | / | 0.452 | |
| 1pow | FAD | Pyruvate oxidase | 1.2.3.3 | 0.452 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.452 | |
| 1qy5 | NEC | Endoplasmin | / | 0.452 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.452 | |
| 1zmc | NAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.452 | |
| 2bri | ANP | Uridylate kinase | 2.7.4.22 | 0.452 | |
| 2d8a | NAD | L-threonine 3-dehydrogenase | / | 0.452 | |
| 2h3w | COA | Carnitine O-acetyltransferase | 2.3.1.7 | 0.452 | |
| 2onm | ADP | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.452 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.452 | |
| 2p9g | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.452 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.452 | |
| 3e8x | NAP | BH1520 protein | / | 0.452 | |
| 3elj | GS7 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.452 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.452 | |
| 3ik6 | HCZ | Glutamate receptor 2 | / | 0.452 | |
| 3koy | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.452 | |
| 3rf7 | NAD | Iron-containing alcohol dehydrogenase | / | 0.452 | |
| 3w33 | W19 | Epidermal growth factor receptor | 2.7.10.1 | 0.452 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 4h0x | NAD | Iota toxin component Ia | / | 0.452 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.452 | |
| 4jb1 | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.452 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.452 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.452 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.451 | |
| 1i9c | 5AD | Glutamate mutase epsilon subunit | / | 0.451 | |
| 1j21 | ATP | Argininosuccinate synthase | / | 0.451 | |
| 1kfc | IPL | Tryptophan synthase alpha chain | / | 0.451 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.451 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.451 | |
| 1u1i | NAD | Myo-inositol-1-phosphate synthase (Ino1) | / | 0.451 | |
| 1uu9 | BI3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.451 | |
| 2daa | DCS | D-alanine aminotransferase | 2.6.1.21 | 0.451 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.451 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.451 | |
| 2xh9 | J01 | Uncharacterized protein | / | 0.451 | |
| 2xpw | OTC | Tetracycline repressor protein class D | / | 0.451 | |
| 2ylx | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.451 | |
| 3a3b | RBF | Lumazine protein | / | 0.451 | |
| 3akz | GSU | Glutamate--tRNA ligase 2 | / | 0.451 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.451 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.451 | |
| 4f7i | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.451 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.451 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.451 | |
| 5kjc | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.451 | |
| 1c6y | MK1 | Protease | / | 0.450 | |
| 1hf3 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.450 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.450 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.450 | |
| 1vza | UMP | Thymidylate synthase | / | 0.450 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.450 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.450 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.450 | |
| 2oah | QIN | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 2q3r | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.450 | |
| 2y3r | TIR | TamL | / | 0.450 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.450 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.450 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 3t4n | ADP | 5'-AMP-activated protein kinase subunit gamma | / | 0.450 | |
| 3uqd | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.450 | |
| 3w1t | WRO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.450 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.450 | |
| 4eua | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.450 | |
| 4ku5 | DCC | 3-oxoacyl-[ACP] synthase III | / | 0.450 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.450 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.450 | |
| 4u0z | APC | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.450 | |
| 5kjc | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.450 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.449 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.449 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.449 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 1kvu | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.449 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.449 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.449 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.449 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.449 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.449 | |
| 2yj4 | ATP | Copper-transporting ATPase | / | 0.449 | |
| 3cf0 | ADP | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.449 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.449 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.449 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.449 | |
| 3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.449 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3qyw | 6PB | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.449 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.449 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.449 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.449 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.449 | |
| 1bmd | NAD | Malate dehydrogenase | / | 0.448 | |
| 1c9k | 5GP | Bifunctional adenosylcobalamin biosynthesis protein CobU | / | 0.448 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.448 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.448 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.448 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1omo | NAD | Alanine dehydrogenase | / | 0.448 | |
| 1rb3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.448 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 2c4j | GSO | Glutathione S-transferase Mu 2 | 2.5.1.18 | 0.448 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.448 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.448 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.448 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.448 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.448 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.448 | |
| 2ql6 | ADP | Nicotinamide riboside kinase 1 | / | 0.448 | |
| 2v2v | V12 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.448 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.448 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.448 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.448 | |
| 3ey9 | TDP | Pyruvate dehydrogenase [ubiquinone] | 1.2.5.1 | 0.448 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.448 | |
| 3px3 | T3Q | dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase | 2.1.1.235 | 0.448 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.448 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.448 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.448 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.448 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.448 | |
| 3w32 | W32 | Epidermal growth factor receptor | 2.7.10.1 | 0.448 | |
| 3zhq | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.448 | |
| 4b2g | V1N | Uncharacterized protein | / | 0.448 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.448 | |
| 4ien | COA | Putative acyl-CoA hydrolase | / | 0.448 | |
| 5aga | ANP | DNA polymerase theta | / | 0.448 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.447 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.447 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1i59 | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.447 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.447 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 1udc | UFM | UDP-glucose 4-epimerase | 5.1.3.2 | 0.447 | |
| 1zrq | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.447 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.447 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.447 | |
| 2bal | PQA | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.447 | |
| 2x3n | FAD | Probable FAD-dependent monooxygenase | / | 0.447 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.447 | |
| 2z54 | AB1 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.447 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.447 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.447 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.447 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.447 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.447 | |
| 3n6u | TSU | HTH-type transcriptional regulator TsaR | / | 0.447 | |
| 3nut | SAH | Precorrin-3 methylase | / | 0.447 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3ty3 | GGG | Homoisocitrate dehydrogenase | 1.1.1.87 | 0.447 | |
| 3ut5 | LOC | Tubulin beta chain | / | 0.447 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.447 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.447 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 4azy | 7F3 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.447 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.447 | |
| 4h1m | 0YJ | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.447 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.447 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.447 | |
| 4zlg | LGC | Putative b-glycan phosphorylase | / | 0.447 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.447 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.446 | |
| 1cbq | RE9 | Cellular retinoic acid-binding protein 2 | / | 0.446 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1dxy | NAD | D-2-hydroxyisocaproate dehydrogenase | 1.1.1 | 0.446 | |
| 1e3l | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.446 | |
| 1heu | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 1s20 | NAD | 2,3-diketo-L-gulonate reductase | 1.1.1.130 | 0.446 | |
| 2a7r | 5GP | GMP reductase 2 | / | 0.446 | |
| 2aa3 | AP0 | L-lactate dehydrogenase | / | 0.446 | |
| 2d4v | NAD | Isocitrate dehydrogenase [NADP] | / | 0.446 | |
| 2ejz | SAH | Diphthine synthase | / | 0.446 | |
| 2f3m | GTD | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.446 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.446 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.446 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.446 | |
| 2irz | I02 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 2nni | MTK | Cytochrome P450 2C8 | / | 0.446 | |
| 2y3r | TRK | TamL | / | 0.446 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3ggc | H26 | Hypoxanthine-guanine phosphoribosyltransferase | 2.4.2.8 | 0.446 | |
| 3gwd | NAP | Cyclohexanone monooxygenase | / | 0.446 | |
| 3muo | ZPR | Prolyl endopeptidase | / | 0.446 | |
| 3uku | C69 | Actin-related protein 3 | / | 0.446 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.446 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.446 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 4eqx | FAD | Coenzyme A disulfide reductase | / | 0.446 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.446 | |
| 4hjf | C2E | GGDEF family protein | / | 0.446 | |
| 4lx9 | ACO | N-alpha-acetyltransferase | 2.3.1 | 0.446 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.446 | |
| 1csc | CMC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.445 | |
| 1j4j | ACO | Acetyltransferase | 2.3.1 | 0.445 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.445 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.445 | |
| 1svl | ADP | Large T antigen | 3.6.4 | 0.445 | |
| 1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.445 | |
| 2dpx | GDP | GTP-binding protein RAD | / | 0.445 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.445 | |
| 2y4g | TIR | TamL | / | 0.445 | |
| 3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.445 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.445 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.445 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4d9e | LCS | D-cysteine desulfhydrase | / | 0.445 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.445 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.445 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.445 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.445 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.445 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.445 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.445 | |
| 5b0o | ADP | Flagellum-specific ATP synthase | 3.6.3.14 | 0.445 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1bdm | NAX | Malate dehydrogenase | / | 0.444 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 1daa | PLP | D-alanine aminotransferase | 2.6.1.21 | 0.444 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.444 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.444 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.444 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.444 | |
| 1llq | NAD | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.444 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.444 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.444 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.444 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.444 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.444 | |
| 2ath | 3EA | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.444 | |
| 2ji5 | UTP | Uridylate kinase | 2.7.4.22 | 0.444 | |
| 2qc8 | ADP | Glutamine synthetase | 6.3.1.2 | 0.444 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.444 | |
| 2rg6 | 287 | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 2wf4 | ZY4 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.444 | |
| 3kpb | SAM | Uncharacterized protein MJ0100 | / | 0.444 | |
| 3lpg | Z78 | Beta-glucuronidase | 3.2.1.31 | 0.444 | |
| 3vfq | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.444 | |
| 3vgl | ANP | Glucokinase | / | 0.444 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3zsx | N44 | Integrase | / | 0.444 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
| 4cr8 | NAD | N-acylmannosamine 1-dehydrogenase | 1.1.1.233 | 0.444 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.444 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.444 | |
| 4g48 | PZB | Mycocyclosin synthase | 1.14.21.9 | 0.444 | |
| 4g6h | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.444 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.444 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.444 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.444 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.444 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.443 | |
| 1fml | RTL | Retinol dehydratase | / | 0.443 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.443 | |
| 1ig1 | ANP | Death-associated protein kinase 1 | 2.7.11.1 | 0.443 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.443 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.443 | |
| 1z0a | GDP | Ras-related protein Rab-2A | / | 0.443 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.443 | |
| 2gqt | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.443 | |
| 2vij | C44 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 2xab | VHD | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 3a14 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.443 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.443 | |
| 3cgd | NAD | Coenzyme A disulfide reductase | / | 0.443 | |
| 3dds | 26B | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.443 | |
| 3dgh | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.443 | |
| 3gu8 | 3GU | Death-associated protein kinase 1 | 2.7.11.1 | 0.443 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.443 | |
| 3ksd | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1 | / | 0.443 | |
| 3n0t | OPY | Dipeptidyl peptidase 2 | 3.4.14.2 | 0.443 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.443 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.443 | |
| 4cgd | 8P3 | Integrase | / | 0.443 | |
| 4e4q | RRH | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.443 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.443 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4iaw | LIZ | Neutrophil gelatinase-associated lipocalin | / | 0.443 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.443 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.443 | |
| 4nxw | ADP | Mitochondrial dynamics protein MID51 | / | 0.443 | |
| 4ock | ANP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.443 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.443 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.443 | |
| 5a9s | NAP | Putative dehydrogenase | / | 0.443 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.443 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.442 | |
| 1f20 | NAP | Nitric oxide synthase, brain | 1.14.13.39 | 0.442 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 1iid | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.442 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.442 | |
| 1jum | BER | HTH-type transcriptional regulator QacR | / | 0.442 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1phh | FAD | p-hydroxybenzoate hydroxylase | / | 0.442 | |
| 2b8l | 5HA | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 2cd8 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.442 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2e9z | UTP | Genome polyprotein | / | 0.442 | |
| 2gqw | FAD | Ferredoxin reductase | / | 0.442 | |
| 2oor | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.442 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.442 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.442 | |
| 2wf1 | ZY1 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 3dbv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.442 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.442 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.442 | |
| 3o15 | 3NM | Thiamine-phosphate synthase | / | 0.442 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.442 | |
| 3tza | TZG | Glutamate receptor 2 | / | 0.442 | |
| 3u4c | NDP | NADPH-dependent reductase BacG | / | 0.442 | |
| 3u9e | COA | Lmo1369 protein | / | 0.442 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.442 | |
| 3zhr | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.442 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 4b72 | 2FB | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.442 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.442 | |
| 4kgm | ATP | Uncharacterized protein | / | 0.442 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 4kqr | VPP | Peptidoglycan D,D-transpeptidase FtsI | / | 0.442 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.442 | |
| 4m55 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.442 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.442 | |
| 4n9i | PCG | Catabolite expression activator | / | 0.442 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 4qq3 | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.442 | |
| 5c77 | SAH | Protein arginine N-methyltransferase SFM1 | / | 0.442 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.442 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.441 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1hnc | GDN | Glutathione S-transferase Mu 2 | 2.5.1.18 | 0.441 | |
| 1k0j | FAD | p-hydroxybenzoate hydroxylase | / | 0.441 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.441 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.441 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1tl7 | ONM | Adenylate cyclase type 2 | / | 0.441 | |
| 1tl7 | ONM | Adenylate cyclase type 5 | / | 0.441 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.441 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.441 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.441 | |
| 2g76 | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.441 | |
| 2gmj | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.441 | |
| 2ntr | L00 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2nua | COA | Succinate--CoA ligase [ADP-forming] subunit alpha | 6.2.1.5 | 0.441 | |
| 2v2q | NVG | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.441 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.441 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.441 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.441 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.441 | |
| 3fpj | SAM | Uncharacterized protein | / | 0.441 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.441 | |
| 3gnq | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.441 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.441 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.441 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.441 | |
| 3o15 | IFP | Thiamine-phosphate synthase | / | 0.441 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 3rfx | NAD | Uronate dehydrogenase | / | 0.441 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.441 | |
| 3w0n | ANP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.441 | |
| 3w55 | 1FM | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.441 | |
| 3wfj | NAD | 2-dehydropantoate 2-reductase | / | 0.441 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.441 | |
| 4b00 | I6X | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4fiz | CUE | 17beta-hydroxysteroid dehydrogenase | / | 0.441 | |
| 4h4u | NDP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.441 | |
| 4h8n | NDP | NADPH-dependent conjugated polyketone reductase C2 | / | 0.441 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.441 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.441 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.441 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.441 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.441 | |
| 4u07 | ATP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.441 | |
| 4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.441 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.441 | |
| 1bwa | XV6 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1gad | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.440 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.440 | |
| 1lny | IMO | Adenylosuccinate synthetase isozyme 1 | / | 0.440 | |
| 1lol | XMP | Orotidine 5'-phosphate decarboxylase | 4.1.1.23 | 0.440 | |
| 1lua | NAP | Bifunctional protein MdtA | 1.5.1.5 | 0.440 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.440 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2fsv | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.440 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 2udp | UPP | UDP-glucose 4-epimerase | 5.1.3.2 | 0.440 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.440 | |
| 2wue | KEK | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.440 | |
| 2y05 | RAL | Prostaglandin reductase 1 | / | 0.440 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.440 | |
| 3csd | EMO | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
| 3gst | GPR | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.440 | |
| 3h86 | AP5 | Adenylate kinase | / | 0.440 | |
| 3iup | NDP | Possible NADH oxidoreductase | / | 0.440 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.440 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.440 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.440 | |
| 3t8w | DGZ | M17 leucyl aminopeptidase | / | 0.440 | |
| 3tif | ADP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.440 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.440 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4az3 | S35 | Lysosomal protective protein | 3.4.16.5 | 0.440 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 4do0 | DZA | Histone lysine demethylase PHF8 | 1.14.11.27 | 0.440 | |
| 4jin | 1L7 | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.440 | |
| 4ke0 | 1R8 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4xey | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.440 | |
| 4yek | THM | Thymidine phosphorylase | / | 0.440 |